Annotation Cluster 1,Enrichment Score: 37.120989489115935,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
SP_PIR_KEYWORDS,ribosome,37,32.45614035,4.83E-63,"RPL18, RPL19, RPLP2, RPL36, RPS2, RPS25, RPL30, RPS29, RPL31, RPLP0, RPLP1, RPL8, RPL3, RPL5, RPL11, RPL4, RPS20, RPS21, RPS24, RPL35A, RPS9, RPL27, RPS6, RPS4X, RPS5, RPS8, RPL29, RPS18, RPS19, RPL23, RPS16, RPS14, RPS12, RPS13, RPL37A, RPS11, UBB",113,73,19235,86.27651837,1.16E-60,1.16E-60,6.24E-60
GOTERM_BP_FAT,GO:0006414~translational elongation,42,36.84210526,6.44E-62,"RPL18, RPL19, RPL35, RPLP2, RPL36, RPL38, RPS2, RPS25, RPL30, RPS29, RPL31, RPLP0, RPLP1, RPL8, RPL3, RPL5, RPL11, RPL4, RPS20, RPS21, RPS24, RPL35A, EEF1A1, RPL27, RPS9, EEF2, RPS6, RPS4X, RPS5, RPS8, RPL29, RPS18, RPS19, RPL23, RPS16, RPL41, RPS14, RPS12, RPS13, RPL37A, RPS11, UBB",110,101,13528,51.1409541,5.87E-59,5.87E-59,1.00E-58
GOTERM_CC_FAT,GO:0022626~cytosolic ribosome,37,32.45614035,2.23E-55,"RPL18, RPL19, RPL35, RPLP2, RPL36, RPL38, RPS2, RPS25, RPL30, RPS29, RPL31, RPLP0, RPLP1, RPL8, RPL3, RPL5, RPL11, RPL4, RPS20, RPS21, FTL, RPS24, RPS9, RPS6, RPS4X, RPS5, RPS8, RPL29, RPS18, RPS19, RPS16, RPL41, RPS14, RPS12, RPS13, RPS11, UBB",108,81,12782,54.06195702,3.99E-53,3.99E-53,2.74E-52
SP_PIR_KEYWORDS,ribosomal protein,40,35.0877193,7.50E-51,"RPL18, RPL19, RPL35, RPLP2, RPL36, RPL38, RPS2, RPS25, RPL30, RPS29, RPL31, RPLP0, RPLP1, RPL8, RPL3, RPL5, RPL11, RPL4, RPS20, RPS21, RPS24, RPL35A, RPS9, RPL27, RPS6, RPS4X, RPS5, RPS8, RPL29, RPS18, RPS19, RPL23, RPS16, RPL41, RPS14, RPS12, RPS13, RPL37A, RPS11, UBB",113,188,19235,36.21728488,1.80E-48,9.00E-49,9.68E-48
KEGG_PATHWAY,hsa03010:Ribosome,38,33.33333333,5.05E-48,"RPL18, RPL19, RPL35, RPLP2, RPL36, RPL38, RPS2, RPS25, RPL30, RPS29, RPL31, RPLP0, RPLP1, RPL8, RPL3, RPL5, RPL11, RPL4, RPS20, RPS21, RPS24, RPL35A, RPS9, RPL27, RPS6, RPS4X, RPS5, RPS8, RPL29, RPS18, RPS19, RPL23, RPS16, RPL41, RPS12, RPS13, RPL37A, RPS11",78,87,5085,28.47480106,2.98E-46,2.98E-46,5.04E-45
GOTERM_CC_FAT,GO:0033279~ribosomal subunit,37,32.45614035,1.10E-46,"RPL18, RPL19, RPL35, RPLP2, RPL36, RPL38, RPS2, RPS25, RPL30, RPS29, RPL31, RPLP0, RPLP1, RPL8, RPL3, RPL5, RPL11, RPL4, RPS20, RPS21, FTL, RPS24, RPS9, RPS6, RPS4X, RPS5, RPS8, RPL29, RPS18, RPS19, RPS16, RPL41, RPS14, RPS12, RPS13, RPS11, UBB",108,128,12782,34.21108218,1.96E-44,9.81E-45,1.35E-43
GOTERM_MF_FAT,GO:0003735~structural constituent of ribosome,39,34.21052632,5.84E-46,"RPL18, RPL19, RPL35, RPLP2, RPL36, RPL38, RPS2, RPL30, RPS29, RPL31, RPLP0, RPLP1, RPL8, RPL3, RPL5, RPL11, RPL4, RPS20, RPS21, RPS24, RPL35A, RPS9, RPL27, RPS6, RPS4X, RPS5, RPS8, RPL29, RPS18, RPS19, RPL23, RPS16, RPL41, RPS14, RPS12, RPS13, RPL37A, RPS11, UBB",106,168,12983,28.43311995,1.11E-43,1.11E-43,7.26E-43
SP_PIR_KEYWORDS,protein biosynthesis,37,32.45614035,1.93E-45,"RPL18, RPL19, RPLP2, RPL36, RPS2, RPS25, RPL30, RPS29, RPL31, RPLP0, RPLP1, RPL8, RPL3, RPL5, RPL11, RPS20, RPS21, RPS24, RPL35A, EEF1A1, RPS9, RPL27, EEF2, RPS6, RPS4X, RPS5, RPS8, RPL29, RPS18, RPS19, RPL23, RPS16, RPS14, RPS12, RPS13, RPS11, UBB",113,188,19235,33.50098851,4.64E-43,1.55E-43,2.50E-42
GOTERM_MF_FAT,GO:0005198~structural molecule activity,56,49.12280702,2.15E-44,"RPL18, RPL19, RPLP2, RPS2, ACTG1, RPLP0, RPLP1, RPL11, TUBA1A, TUBA1B, RPL35A, RPS4X, RPS18, BGN, RPS19, RPL41, RPS16, RPS14, COL1A2, RPS12, RPS13, RPS11, UBB, MYL6, VIM, RPL35, RPL36, RPL38, TPM2, TPM1, TPM4, MYL9, RPL30, TUBB, RPS29, ARPC2, RPL31, RPL8, RPL3, COL6A2, RPL5, RPL4, RPS20, RPS21, RPS24, ACTB, COL4A2, COL4A1, RPL27, RPS9, RPS6, RPS5, RPS8, RPL29, RPL23, RPL37A",106,634,12983,10.81852271,4.10E-42,2.05E-42,2.67E-41
GOTERM_CC_FAT,GO:0005840~ribosome,41,35.96491228,3.89E-44,"RPL18, RPL19, RPL35, RPLP2, RPL36, RPL38, RPS2, RPS25, RPL30, RPS29, RPL31, RPLP0, RPLP1, RPL8, RPL3, RPL5, RPL11, RPL4, RPS20, RPS21, FTL, RPS24, RPL35A, RPL27, RPS9, RPS6, RPS4X, RPS5, RPS8, RPL29, RPS18, RPS19, RPL23, RPS16, RPL41, RPS14, RPS12, RPS13, RPL37A, RPS11, UBB",108,215,12782,22.56942291,6.96E-42,2.32E-42,4.78E-41
SP_PIR_KEYWORDS,ribonucleoprotein,40,35.0877193,1.10E-43,"RPL18, RPL19, RPL35, RPLP2, RPL36, RPL38, RPS2, RPS25, RPL30, RPS29, RPL31, RPLP0, RPLP1, RPL8, RPL3, RPL5, RPL11, RPL4, RPS20, RPS21, RPS24, RPL35A, RPS9, RPL27, RPS6, RPS4X, RPS5, RPS8, RPL29, RPS18, RPS19, RPL23, RPS16, RPL41, RPS14, RPS12, RPS13, RPL37A, RPS11, UBB",113,279,19235,24.4044787,2.64E-41,6.60E-42,1.42E-40
GOTERM_CC_FAT,GO:0044445~cytosolic part,37,32.45614035,1.19E-43,"RPL18, RPL19, RPL35, RPLP2, RPL36, RPL38, RPS2, RPS25, RPL30, RPS29, RPL31, RPLP0, RPLP1, RPL8, RPL3, RPL5, RPL11, RPL4, RPS20, RPS21, FTL, RPS24, RPS9, RPS6, RPS4X, RPS5, RPS8, RPL29, RPS18, RPS19, RPS16, RPL41, RPS14, RPS12, RPS13, RPS11, UBB",108,152,12782,28.80933236,2.14E-41,5.34E-42,1.47E-40
GOTERM_BP_FAT,GO:0006412~translation,42,36.84210526,2.71E-38,"RPL18, RPL19, RPL35, RPLP2, RPL36, RPL38, RPS2, RPS25, RPL30, RPS29, RPL31, RPLP0, RPLP1, RPL8, RPL3, RPL5, RPL11, RPL4, RPS20, RPS21, RPS24, RPL35A, EEF1A1, RPL27, RPS9, EEF2, RPS6, RPS4X, RPS5, RPS8, RPL29, RPS18, RPS19, RPL23, RPS16, RPL41, RPS14, RPS12, RPS13, RPL37A, RPS11, UBB",110,331,13528,15.6049437,2.47E-35,1.24E-35,4.23E-35
SP_PIR_KEYWORDS,acetylation,74,64.9122807,3.18E-36,"RPL18, S100A6, RPL19, UCHL1, RPLP2, RPS2, ACTG1, RPLP0, RPLP1, TPT1, RPL11, FTL, RPL35A, EEF2, TMSB10, RPS4X, RPS18, RPS19, RPS16, TAGLN, PKM2, CFL1, RPS12, HSPB1, RPS13, TMSB4X, RPS11, UBB, PTMS, GSTP1, MYL6, ALDOA, VIM, RPL35, RPL36, RPL38, TAGLN2, CALR, TPM2, TPM1, ITGB1, TPM4, MIF, MYL9, RPS25, PFN1, TUBB, RPL30, RPS29, ARPC2, RPL31, RPL8, RPL3, RPL5, RPL4, RPS20, RPS21, GAPDH, RPS24, ACTB, EEF1A1, LGALS1, S100A11, RPL27, RPS9, MYL12A, ANXA5, RPS6, RPS5, RPL29, ANXA2, MT2A, GNB2L1, CALM2",113,2635,19235,4.78040671,7.63E-34,1.53E-34,4.11E-33
GOTERM_CC_FAT,GO:0030529~ribonucleoprotein complex,44,38.59649123,2.65E-32,"RPL18, RPL19, RPL35, RPLP2, RPL36, RPL38, CALR, RPS2, RPS25, RPL30, RPS29, RPL31, RPLP0, RPLP1, RPL8, RPL3, RPL5, RPL11, RPL4, RPS20, RPS21, FTL, RPS24, ACTB, RPL35A, RPL27, RPS9, EEF2, RPS6, RPS4X, RPS5, RPS8, RPL29, RPS18, RPS19, RPL23, RPS16, RPL41, RPS14, RPS12, RPS13, RPL37A, RPS11, UBB",108,515,12782,10.11161453,4.74E-30,9.49E-31,3.26E-29
GOTERM_CC_FAT,GO:0022627~cytosolic small ribosomal subunit,20,17.54385965,7.18E-30,"RPS9, RPS2, RPS6, RPS4X, RPS5, RPS8, RPS25, RPS18, RPS19, RPS29, RPS16, RPS14, RPS12, RPS13, UBB, RPS11, RPS20, RPS21, FTL, RPS24",108,40,12782,59.17592593,1.28E-27,2.14E-28,8.83E-27
GOTERM_CC_FAT,GO:0015935~small ribosomal subunit,20,17.54385965,2.86E-25,"RPS9, RPS2, RPS6, RPS4X, RPS5, RPS8, RPS25, RPS18, RPS19, RPS29, RPS16, RPS14, RPS12, RPS13, UBB, RPS11, RPS20, RPS21, FTL, RPS24",108,63,12782,37.57201646,5.11E-23,7.31E-24,3.52E-22
GOTERM_CC_FAT,GO:0022625~cytosolic large ribosomal subunit,17,14.9122807,3.43E-24,"RPL18, RPL19, RPL35, RPLP2, RPL36, RPL38, RPL29, RPL30, RPL41, RPL31, RPLP0, RPLP1, RPL8, RPL3, RPL5, RPL11, RPL4",108,38,12782,52.94688109,6.13E-22,7.67E-23,4.22E-21
GOTERM_CC_FAT,GO:0005829~cytosol,52,45.61403509,9.27E-23,"RPL18, RPL19, UCHL1, RPLP2, RPS2, ACTG1, RPLP0, RPLP1, RPL11, TUBA1A, FTL, RPL35A, RPS4X, RPS18, RPS19, RPL41, RPS16, PKM2, RPS14, RPS12, RPS13, RPS11, UBB, PTMS, VIM, RPL35, RPL36, RPL38, CALR, RPS25, RPL30, TUBB, RPS29, RPL31, RPL8, RPL3, RPL5, RPL4, RPS20, RPS21, RPS24, ACTB, EEF1A1, RPS9, RPL27, RPS6, RPS5, RPS8, RPL29, RPL23, RPL37A, CALM2",108,1330,12782,4.627290448,1.66E-20,1.84E-21,1.14E-19
GOTERM_CC_FAT,GO:0015934~large ribosomal subunit,17,14.9122807,1.41E-19,"RPL18, RPL19, RPL35, RPLP2, RPL36, RPL38, RPL29, RPL30, RPL41, RPL31, RPLP0, RPLP1, RPL8, RPL3, RPL5, RPL11, RPL4",108,67,12782,30.02957435,2.52E-17,2.52E-18,1.73E-16
GOTERM_CC_FAT,GO:0043228~non-membrane-bounded organelle,63,55.26315789,9.68E-18,"RPL18, RPL19, UCHL1, RPLP2, RPS2, ACTG1, RPLP0, RPLP1, TPT1, RPL11, TUBA1A, TUBA1B, FTL, RPL35A, TMSB10, RPS4X, RPS18, RPS19, RPL41, RPS16, RPS14, CFL1, RPS12, HSPB1, RPS13, TMSB4X, RPS11, UBB, ALDOA, MYL6, VIM, RPL35, RPL36, RPL38, TPM2, TPM1, TPM4, MYL9, RPS25, PFN1, RPL30, TUBB, RPS29, ARPC2, RPL31, RPL8, RPL3, RPL5, RPL4, RPS20, RPS21, RPS24, ACTB, RPL27, RPS9, MYL12A, RPS6, RPS5, RPS8, RPL29, RPL23, RPL37A, CALM2",108,2596,12782,2.872175141,1.73E-15,1.58E-16,1.19E-14
GOTERM_CC_FAT,GO:0043232~intracellular non-membrane-bounded organelle,63,55.26315789,9.68E-18,"RPL18, RPL19, UCHL1, RPLP2, RPS2, ACTG1, RPLP0, RPLP1, TPT1, RPL11, TUBA1A, TUBA1B, FTL, RPL35A, TMSB10, RPS4X, RPS18, RPS19, RPL41, RPS16, RPS14, CFL1, RPS12, HSPB1, RPS13, TMSB4X, RPS11, UBB, ALDOA, MYL6, VIM, RPL35, RPL36, RPL38, TPM2, TPM1, TPM4, MYL9, RPS25, PFN1, RPL30, TUBB, RPS29, ARPC2, RPL31, RPL8, RPL3, RPL5, RPL4, RPS20, RPS21, RPS24, ACTB, RPL27, RPS9, MYL12A, RPS6, RPS5, RPS8, RPL29, RPL23, RPL37A, CALM2",108,2596,12782,2.872175141,1.73E-15,1.58E-16,1.19E-14
GOTERM_MF_FAT,GO:0003723~RNA binding,30,26.31578947,2.36E-13,"RPL18, RPL19, RPL35, RPLP2, RPL38, RPS2, CALR, RPS25, RPL30, RPL31, RPLP0, RPL8, RPLP1, RPL3, RPL5, RPL11, RPL4, RPS20, RPL35A, RPS9, RPS4X, RPS5, RPL29, RPS18, RPS19, RPS16, RPL41, RPS14, RPS13, RPS11",106,718,12983,5.117596048,4.52E-11,1.51E-11,2.94E-10
,,,,,,,,,,,,
Annotation Cluster 2,Enrichment Score: 5.939024681557921,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
SP_PIR_KEYWORDS,rrna-binding,7,6.140350877,4.00E-10,"RPS18, RPL8, RPS9, RPL5, RPL11, RPS11, RPS4X",113,17,19235,70.09109839,9.60E-08,1.37E-08,5.16E-07
GOTERM_MF_FAT,GO:0019843~rRNA binding,7,6.140350877,9.90E-08,"RPS18, RPL8, RPS9, RPL5, RPL11, RPS11, RPS4X",106,29,12983,29.56441119,1.89E-05,4.73E-06,1.23E-04
SP_PIR_KEYWORDS,rna-binding,8,7.01754386,0.038507683,"RPL35A, RPS18, RPL8, RPS9, RPL5, RPL11, RPS11, RPS4X",113,540,19235,2.521796132,0.999919277,0.205359598,39.761631
,,,,,,,,,,,,
Annotation Cluster 3,Enrichment Score: 4.155872758534239,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
SP_PIR_KEYWORDS,diamond-blackfan anemia,5,4.385964912,3.76E-08,"RPL35A, RPS19, RPL5, RPL11, RPS24",113,7,19235,121.5865992,9.03E-06,1.00E-06,4.85E-05
GOTERM_BP_FAT,GO:0042274~ribosomal small subunit biogenesis,5,4.385964912,1.26E-06,"RPS19, RPS16, RPS14, RPS6, RPS24",110,11,13528,55.90082645,0.001148492,3.83E-04,0.001967419
GOTERM_BP_FAT,GO:0042254~ribosome biogenesis,9,7.894736842,6.17E-06,"RPL35A, RPS19, RPS16, RPS14, RPLP0, RPL5, RPL11, RPS6, RPS24",110,122,13528,9.07242921,0.005612062,0.001405978,0.009634891
GOTERM_BP_FAT,GO:0006364~rRNA processing,8,7.01754386,9.06E-06,"RPL35A, RPS19, RPS16, RPS14, RPL5, RPL11, RPS6, RPS24",110,92,13528,10.69407115,0.008229052,0.001651255,0.014146074
GOTERM_BP_FAT,GO:0016072~rRNA metabolic process,8,7.01754386,1.20E-05,"RPL35A, RPS19, RPS16, RPS14, RPL5, RPL11, RPS6, RPS24",110,96,13528,10.24848485,0.010889922,0.001823278,0.018744909
GOTERM_BP_FAT,GO:0022613~ribonucleoprotein complex biogenesis,9,7.894736842,1.02E-04,"RPL35A, RPS19, RPS16, RPS14, RPLP0, RPL5, RPL11, RPS6, RPS24",110,180,13528,6.149090909,0.088658492,0.010262267,0.158819009
GOTERM_BP_FAT,GO:0034470~ncRNA processing,8,7.01754386,7.84E-04,"RPL35A, RPS19, RPS16, RPS14, RPL5, RPL11, RPS6, RPS24",110,187,13528,5.261254254,0.510956287,0.053536941,1.217187438
GOTERM_BP_FAT,GO:0034660~ncRNA metabolic process,8,7.01754386,0.002573785,"RPL35A, RPS19, RPS16, RPS14, RPL5, RPL11, RPS6, RPS24",110,230,13528,4.277628458,0.904661129,0.129122522,3.944044247
GOTERM_BP_FAT,GO:0042273~ribosomal large subunit biogenesis,3,2.631578947,0.002775207,"RPL35A, RPL5, RPL11",110,10,13528,36.89454545,0.920699242,0.124880768,4.246477366
GOTERM_BP_FAT,GO:0006396~RNA processing,8,7.01754386,0.152322735,"RPL35A, RPS19, RPS16, RPS14, RPL5, RPL11, RPS6, RPS24",110,547,13528,1.798637195,1,0.80566717,92.42504333
,,,,,,,,,,,,
Annotation Cluster 4,Enrichment Score: 3.516242834356398,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
SP_PIR_KEYWORDS,extracellular matrix,14,12.28070175,1.54E-09,"COL4A2, COL4A1, LGALS1, POSTN, SPARC, CALR, MMP1, ANXA2, BGN, CTGF, TGFBI, COL1A2, COL6A2, COL6A1",113,241,19235,9.888370727,3.69E-07,4.61E-08,1.99E-06
GOTERM_CC_FAT,GO:0005578~proteinaceous extracellular matrix,17,14.9122807,9.06E-09,"COL4A2, COL4A1, LGALS1, POSTN, SPARC, MMP14, CALR, MMP1, ANXA2, TIMP1, ANXA2P2, BGN, CTGF, TGFBI, COL1A2, COL6A2, COL6A1",108,320,12782,6.28744213,1.62E-06,1.35E-07,1.11E-05
GOTERM_CC_FAT,GO:0031012~extracellular matrix,17,14.9122807,2.62E-08,"COL4A2, COL4A1, LGALS1, POSTN, SPARC, MMP14, CALR, MMP1, ANXA2, TIMP1, ANXA2P2, BGN, CTGF, TGFBI, COL1A2, COL6A2, COL6A1",108,345,12782,5.831830381,4.68E-06,3.60E-07,3.22E-05
GOTERM_CC_FAT,GO:0044421~extracellular region part,25,21.92982456,9.43E-07,"ALDOA, CCL2, IGFBP7, FSTL1, POSTN, CALR, MMP1, TIMP1, MIF, CTGF, TGFBI, TPT1, COL6A2, COL6A1, COL4A2, COL4A1, PSAP, LGALS1, SPARC, MMP14, ANXA2, ANXA2P2, BGN, COL1A2, IGFBP2",108,960,12782,3.082079475,1.69E-04,1.21E-05,0.001160499
GOTERM_BP_FAT,GO:0030198~extracellular matrix organization,8,7.01754386,2.03E-05,"COL4A2, TGFBI, COL1A2, COL6A2, POSTN, SERPINH1, ANXA2P2, ANXA2",110,104,13528,9.46013986,0.018342345,0.00264117,0.031690096
GOTERM_BP_FAT,GO:0043062~extracellular structure organization,8,7.01754386,3.45E-04,"COL4A2, TGFBI, COL1A2, COL6A2, POSTN, SERPINH1, ANXA2P2, ANXA2",110,163,13528,6.035917457,0.269974056,0.028201535,0.53730012
GOTERM_CC_FAT,GO:0044420~extracellular matrix part,7,6.140350877,4.41E-04,"COL4A2, COL4A1, COL1A2, COL6A1, SPARC, ANXA2P2, ANXA2",108,117,12782,7.080880025,0.075879331,0.003937857,0.541045307
SP_PIR_KEYWORDS,Secreted,22,19.29824561,6.80E-04,"COL4A2, CCL2, COL4A1, LGALS1, IGFBP7, POSTN, FSTL1, SPARC, CALR, MMP1, MIF, B2M, TIMP1, ANXA2, BGN, CTGF, TGFBI, SERPINE1, COL1A2, COL6A2, COL6A1, IGFBP2",113,1689,19235,2.217209743,0.150724856,0.006263841,0.874786438
GOTERM_CC_FAT,GO:0005576~extracellular region,30,26.31578947,0.001773558,"ALDOA, CCL2, IGFBP7, FSTL1, POSTN, CALR, MMP1, MIF, TIMP1, B2M, CTGF, TGFBI, SERPINE1, TPT1, COL6A2, COL6A1, P4HB, COL4A2, COL4A1, PSAP, LGALS1, SPARC, MMP14, ANXA2, ANXA2P2, BGN, COL1A2, GNAS, IGFBP2, CALM2",108,2010,12782,1.76644555,0.272214319,0.01433932,2.160794766
SP_PIR_KEYWORDS,signal,27,23.68421053,0.052336241,"CCL2, TNFRSF12A, IGFBP7, FSTL1, POSTN, CALR, SERPINH1, ITGB1, MMP1, TIMP1, B2M, CTGF, TGFBI, SERPINE1, COL6A2, COL6A1, P4HB, COL4A2, BSG, COL4A1, PSAP, SPARC, MMP14, BGN, PPIB, COL1A2, IGFBP2",113,3250,19235,1.414145677,0.999997505,0.259204622,50.03509119
UP_SEQ_FEATURE,signal peptide,27,23.68421053,0.055832409,"CCL2, TNFRSF12A, IGFBP7, FSTL1, POSTN, CALR, SERPINH1, ITGB1, MMP1, TIMP1, B2M, CTGF, TGFBI, SERPINE1, COL6A2, COL6A1, P4HB, COL4A2, BSG, COL4A1, PSAP, SPARC, MMP14, BGN, PPIB, COL1A2, IGFBP2",113,3250,19113,1.40517631,0.999999998,0.841764987,54.46779623
UP_SEQ_FEATURE,disulfide bond,22,19.29824561,0.144175939,"P4HB, BSG, COL4A2, CCL2, COL4A1, TNFRSF12A, PSAP, IGFBP7, S100A11, POSTN, FSTL1, SPARC, CALR, MMP14, ITGB1, MMP1, B2M, TIMP1, BGN, CTGF, TGFBI, IGFBP2",113,2819,19113,1.320012431,1,0.98974402,88.14057581
SP_PIR_KEYWORDS,disulfide bond,22,19.29824561,0.178068688,"P4HB, BSG, COL4A2, CCL2, COL4A1, TNFRSF12A, PSAP, IGFBP7, S100A11, POSTN, FSTL1, SPARC, CALR, MMP14, ITGB1, MMP1, B2M, TIMP1, BGN, CTGF, TGFBI, IGFBP2",113,2924,19235,1.280734356,1,0.624873601,92.04317445
SP_PIR_KEYWORDS,glycoprotein,29,25.43859649,0.29118706,"IER3, CCL2, IGFBP7, UCHL1, FSTL1, POSTN, CALR, CD151, SERPINH1, ITGB1, MMP1, TIMP1, B2M, CTGF, SERPINE1, COL6A2, COL6A1, BSG, COL4A2, COL4A1, PSAP, SPARC, MMP14, CD63, BGN, PPIB, COL1A2, GNAS, IGFBP2",113,4318,19235,1.14321814,1,0.789543603,98.82310528
UP_SEQ_FEATURE,glycosylation site:N-linked (GlcNAc...),24,21.05263158,0.644929508,"IER3, BSG, COL4A2, CCL2, COL4A1, PSAP, IGFBP7, POSTN, FSTL1, SPARC, CALR, CD63, CD151, SERPINH1, ITGB1, MMP1, TIMP1, BGN, PPIB, CTGF, SERPINE1, COL1A2, COL6A2, COL6A1",113,4129,19113,0.98314319,1,1,99.99993051
,,,,,,,,,,,,
Annotation Cluster 5,Enrichment Score: 3.0880040254164363,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
SP_PIR_KEYWORDS,collagen,7,6.140350877,1.94E-05,"COL4A2, COL4A1, COL1A2, COL6A2, COL6A1, MMP1, TIMP1",113,95,19235,12.54261761,0.004651816,3.88E-04,0.025073269
SP_PIR_KEYWORDS,triple helix,5,4.385964912,3.04E-05,"COL4A2, COL4A1, COL1A2, COL6A2, COL6A1",113,31,19235,27.45503854,0.007259251,5.20E-04,0.039175865
SP_PIR_KEYWORDS,hydroxylysine,5,4.385964912,3.04E-05,"COL4A2, COL4A1, COL1A2, COL6A2, COL6A1",113,31,19235,27.45503854,0.007259251,5.20E-04,0.039175865
SP_PIR_KEYWORDS,hydroxyproline,5,4.385964912,6.20E-05,"COL4A2, COL4A1, COL1A2, COL6A2, COL6A1",113,37,19235,23.00287013,0.014776827,9.30E-04,0.080032578
SP_PIR_KEYWORDS,cell binding,4,3.50877193,8.31E-05,"COL4A2, COL4A1, COL6A2, COL6A1",113,15,19235,45.39233038,0.019745674,0.001172443,0.107199626
UP_SEQ_FEATURE,region of interest:Triple-helical region,4,3.50877193,3.18E-04,"COL4A2, COL4A1, COL6A2, COL6A1",113,23,19113,29.4159292,0.106350776,0.054669781,0.435252867
GOTERM_CC_FAT,GO:0044420~extracellular matrix part,7,6.140350877,4.41E-04,"COL4A2, COL4A1, COL1A2, COL6A1, SPARC, ANXA2P2, ANXA2",108,117,12782,7.080880025,0.075879331,0.003937857,0.541045307
SP_PIR_KEYWORDS,trimer,4,3.50877193,4.53E-04,"COL4A1, COL1A2, COL6A2, COL6A1",113,26,19235,26.18788291,0.103077633,0.004932611,0.583356213
SP_PIR_KEYWORDS,hydroxylation,5,4.385964912,7.84E-04,"COL4A2, COL4A1, COL1A2, COL6A2, COL6A1",113,71,19235,11.98741119,0.171557061,0.006946403,1.007096683
INTERPRO,IPR008160:Collagen triple helix repeat,5,4.385964912,0.002392044,"COL4A2, COL4A1, COL1A2, COL6A2, COL6A1",112,84,16659,8.853635204,0.474933665,0.14875702,3.09804424
SP_PIR_KEYWORDS,pyroglutamic acid,4,3.50877193,0.002431425,"CCL2, COL1A2, COL6A2, COL6A1",113,46,19235,14.80184686,0.442477583,0.018670365,3.093328977
GOTERM_CC_FAT,GO:0005581~collagen,4,3.50877193,0.003072384,"COL4A2, COL4A1, COL1A2, COL6A1",108,35,12782,13.52592593,0.423513477,0.022688787,3.71590378
KEGG_PATHWAY,hsa04510:Focal adhesion,10,8.771929825,0.003084545,"ACTG1, ACTB, COL4A2, COL4A1, COL1A2, COL6A2, COL6A1, MYL12A, ITGB1, MYL9",78,201,5085,3.243398393,0.166623187,0.044544745,3.037833582
GOTERM_MF_FAT,GO:0048407~platelet-derived growth factor binding,3,2.631578947,0.003397727,"COL4A1, COL1A2, COL6A1",106,11,12983,33.40394511,0.47799125,0.052731385,4.145399501
GOTERM_MF_FAT,GO:0005201~extracellular matrix structural constituent,5,4.385964912,0.005163143,"COL4A2, BGN, COL4A1, COL1A2, COL6A2",106,86,12983,7.120996051,0.627945512,0.068186412,6.236344955
KEGG_PATHWAY,hsa04512:ECM-receptor interaction,6,5.263157895,0.008501071,"COL4A2, COL4A1, COL1A2, COL6A2, COL6A1, ITGB1",78,84,5085,4.656593407,0.395713756,0.09583323,8.172014858
SP_PIR_KEYWORDS,coiled coil,10,8.771929825,0.84367981,"COL4A2, COL4A1, VIM, COL1A2, COL6A2, COL6A1, GNAS, TPM2, TPM1, TPM4",113,2019,19235,0.843096775,1,0.999402882,100
,,,,,,,,,,,,
Annotation Cluster 6,Enrichment Score: 2.9027259495069004,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_CC_FAT,GO:0042383~sarcolemma,8,7.01754386,1.36E-06,"BSG, BGN, COL6A2, COL6A1, GNAS, ITGB1, ANXA2P2, ANXA2",108,67,12782,14.1315644,2.43E-04,1.62E-05,0.001674127
GOTERM_CC_FAT,GO:0042470~melanosome,7,6.140350877,9.89E-05,"P4HB, BSG, PPIB, MMP14, ITGB1, ANXA2P2, ANXA2",108,89,12782,9.308572618,0.017550041,0.001040979,0.121651544
GOTERM_CC_FAT,GO:0048770~pigment granule,7,6.140350877,9.89E-05,"P4HB, BSG, PPIB, MMP14, ITGB1, ANXA2P2, ANXA2",108,89,12782,9.308572618,0.017550041,0.001040979,0.121651544
GOTERM_CC_FAT,GO:0031982~vesicle,13,11.40350877,0.010123412,"ALDOA, P4HB, BSG, BGN, PPIB, GNAS, SPARC, IGFBP2, MMP14, ITGB1, ANXA2P2, TIMP1, ANXA2",108,670,12782,2.296379215,0.838188849,0.057059817,11.76917618
GOTERM_CC_FAT,GO:0031988~membrane-bounded vesicle,11,9.649122807,0.020526816,"ALDOA, P4HB, BSG, BGN, PPIB, SPARC, MMP14, ITGB1, ANXA2P2, TIMP1, ANXA2",108,568,12782,2.2920253,0.97558445,0.100640495,22.52633193
GOTERM_CC_FAT,GO:0016023~cytoplasmic membrane-bounded vesicle,10,8.771929825,0.040888295,"P4HB, BSG, BGN, PPIB, SPARC, MMP14, ITGB1, ANXA2P2, TIMP1, ANXA2",108,550,12782,2.151851852,0.99943169,0.174372335,40.17511768
GOTERM_CC_FAT,GO:0031410~cytoplasmic vesicle,11,9.649122807,0.042414207,"P4HB, BSG, BGN, PPIB, SPARC, MMP14, IGFBP2, ITGB1, ANXA2P2, TIMP1, ANXA2",108,642,12782,2.027835468,0.999572627,0.176297885,41.33591886
,,,,,,,,,,,,
Annotation Cluster 7,Enrichment Score: 2.8542622071516095,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_CC_FAT,GO:0044420~extracellular matrix part,7,6.140350877,4.41E-04,"COL4A2, COL4A1, COL1A2, COL6A1, SPARC, ANXA2P2, ANXA2",108,117,12782,7.080880025,0.075879331,0.003937857,0.541045307
SP_PIR_KEYWORDS,basement membrane,4,3.50877193,0.001507689,"COL4A2, COL4A1, SPARC, ANXA2",113,39,19235,17.45858861,0.303799998,0.011998052,1.928675376
GOTERM_CC_FAT,GO:0005604~basement membrane,5,4.385964912,0.004118168,"COL4A2, COL4A1, SPARC, ANXA2P2, ANXA2",108,78,12782,7.58665717,0.522253041,0.028010756,4.951500581
,,,,,,,,,,,,
Annotation Cluster 8,Enrichment Score: 2.7435706737621337,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
SP_PIR_KEYWORDS,muscle protein,7,6.140350877,1.32E-06,"MYL6, TAGLN, MYL12A, TPM2, TPM1, TPM4, MYL9",113,60,19235,19.85914454,3.17E-04,3.17E-05,0.001703752
INTERPRO,IPR000533:Tropomyosin,3,2.631578947,2.62E-04,"TPM2, TPM1, TPM4",112,4,16659,111.5558036,0.067984352,0.034590425,0.343338945
GOTERM_MF_FAT,GO:0008307~structural constituent of muscle,5,4.385964912,3.57E-04,"MYL6, TPM2, TPM1, TPM4, MYL9",106,42,12983,14.58108715,0.065920389,0.009694645,0.443145494
GOTERM_CC_FAT,GO:0005862~muscle thin filament tropomyosin,3,2.631578947,4.12E-04,"TPM2, TPM1, TPM4",108,4,12782,88.76388889,0.071110092,0.003874845,0.50584167
PIR_SUPERFAMILY,PIRSF002327:tropomyosin,3,2.631578947,0.001024865,"TPM2, TPM1, TPM4",99,4,7396,56.03030303,0.096531192,0.096531192,1.129534867
GOTERM_CC_FAT,GO:0044449~contractile fiber part,6,5.263157895,0.002567807,"ALDOA, HSPB1, TPM2, TPM1, TPM4, MYL9",108,113,12782,6.284169125,0.368860678,0.019811071,3.114482395
GOTERM_CC_FAT,GO:0043292~contractile fiber,6,5.263157895,0.003450521,"ALDOA, HSPB1, TPM2, TPM1, TPM4, MYL9",108,121,12782,5.868686869,0.461361901,0.024444722,4.164367295
GOTERM_CC_FAT,GO:0005865~striated muscle thin filament,3,2.631578947,0.006789292,"TPM2, TPM1, TPM4",108,15,12782,23.67037037,0.704600781,0.042616258,8.041619494
KEGG_PATHWAY,hsa05410:Hypertrophic cardiomyopathy (HCM),6,5.263157895,0.008927541,"ACTG1, ACTB, TPM2, TPM1, ITGB1, TPM4",78,85,5085,4.601809955,0.410859262,0.084405499,8.565669731
GOTERM_CC_FAT,GO:0030017~sarcomere,5,4.385964912,0.009185484,"ALDOA, HSPB1, TPM2, TPM1, TPM4",108,98,12782,6.038359788,0.808295389,0.055366829,10.7348583
GOTERM_CC_FAT,GO:0030016~myofibril,5,4.385964912,0.014027763,"ALDOA, HSPB1, TPM2, TPM1, TPM4",108,111,12782,5.331164498,0.920241161,0.075981666,15.95755324
KEGG_PATHWAY,hsa04260:Cardiac muscle contraction,3,2.631578947,0.331500273,"TPM2, TPM1, TPM4",78,78,5085,2.50739645,1,0.79485315,98.20736543
,,,,,,,,,,,,
Annotation Cluster 9,Enrichment Score: 2.40750661552049,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
UP_SEQ_FEATURE,cross-link:Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin),9,7.894736842,2.26E-05,"PFN1, TUBB, GNAS, UBB, RPS20, TPM1, TUBA1B, CALM2, RPL29",113,199,19113,7.64961978,0.007951575,0.007951575,0.030965526
SP_PIR_KEYWORDS,isopeptide bond,9,7.894736842,5.60E-04,"PFN1, TUBB, GNAS, UBB, RPS20, TPM1, TUBA1B, CALM2, RPL29",113,319,19235,4.802480095,0.125742126,0.005360775,0.720106413
SP_PIR_KEYWORDS,ubl conjugation,9,7.894736842,0.021610291,"PFN1, TUBB, GNAS, UBB, RPS20, TPM1, TUBA1B, CALM2, RPL29",113,588,19235,2.605427127,0.99471737,0.132128532,24.57209076
GOTERM_BP_FAT,GO:0044093~positive regulation of molecular function,4,3.50877193,0.856851317,"GNAS, UBB, TPM1, CALM2",110,586,13528,0.839466336,1,0.99990689,100
,,,,,,,,,,,,
Annotation Cluster 10,Enrichment Score: 2.273178924337568,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
SP_PIR_KEYWORDS,muscle protein,7,6.140350877,1.32E-06,"MYL6, TAGLN, MYL12A, TPM2, TPM1, TPM4, MYL9",113,60,19235,19.85914454,3.17E-04,3.17E-05,0.001703752
GOTERM_CC_FAT,GO:0015629~actin cytoskeleton,11,9.649122807,8.42E-05,"MYL6, ACTG1, ALDOA, PFN1, ARPC2, CFL1, MYL12A, TPM2, TPM1, TPM4, MYL9",108,269,12782,4.839666804,0.014958099,9.42E-04,0.103558238
SP_PIR_KEYWORDS,actin-binding,9,7.894736842,9.95E-05,"PFN1, TAGLN, ARPC2, CFL1, TMSB4X, TMSB10, TPM2, TPM1, TPM4",113,247,19235,6.202393322,0.02359246,0.001255801,0.128321473
GOTERM_BP_FAT,GO:0030029~actin filament-based process,10,8.771929825,1.41E-04,"MYL6, ACTG1, ALDOA, PFN1, CFL1, TMSB4X, TMSB10, CALR, TPM1, ITGB1",110,241,13528,5.102980008,0.120850534,0.012797443,0.220273406
GOTERM_BP_FAT,GO:0030036~actin cytoskeleton organization,9,7.894736842,4.79E-04,"ACTG1, ALDOA, PFN1, CFL1, TMSB4X, TMSB10, CALR, TPM1, ITGB1",110,226,13528,4.897506034,0.353876564,0.03574265,0.744986751
GOTERM_MF_FAT,GO:0008092~cytoskeletal protein binding,13,11.40350877,7.53E-04,"ALDOA, TMSB10, TPM2, TPM1, TPM4, ANXA2, ANXA2P2, PFN1, TAGLN, ARPC2, CFL1, TMSB4X, CALM2",106,504,12983,3.15923555,0.133957505,0.017817029,0.932304035
SP_PIR_KEYWORDS,cytoskeleton,12,10.52631579,0.001210315,"ACTG1, ACTB, PFN1, ARPC2, CFL1, HSPB1, TMSB4X, TMSB10, TPM2, TPM1, CALM2, TPM4",113,636,19235,3.211721489,0.25222379,0.009972409,1.551005921
GOTERM_MF_FAT,GO:0003779~actin binding,10,8.771929825,0.001289707,"ALDOA, PFN1, TAGLN, ARPC2, CFL1, TMSB4X, TMSB10, TPM2, TPM1, TPM4",106,326,12983,3.757089941,0.218463204,0.027016462,1.592539006
GOTERM_BP_FAT,GO:0007010~cytoskeleton organization,11,9.649122807,0.002706332,"ACTG1, ALDOA, PFN1, TUBB, CFL1, TMSB4X, TMSB10, CALR, TPM1, ITGB1, TUBA1B",110,436,13528,3.102752294,0.915543633,0.128297149,4.143161736
GOTERM_BP_FAT,GO:0032956~regulation of actin cytoskeleton organization,5,4.385964912,0.005761288,"ARPC2, CFL1, TMSB4X, TMSB10, TPM1",110,89,13528,6.909090909,0.994853761,0.212996226,8.626785653
GOTERM_BP_FAT,GO:0044087~regulation of cellular component biogenesis,6,5.263157895,0.005796998,"ARPC2, TMSB4X, TMSB10, UBB, MMP14, TPM1",110,142,13528,5.196414853,0.995019601,0.2058893,8.678014444
GOTERM_BP_FAT,GO:0032970~regulation of actin filament-based process,5,4.385964912,0.006473297,"ARPC2, CFL1, TMSB4X, TMSB10, TPM1",110,92,13528,6.683794466,0.99732241,0.210940478,9.643177306
GOTERM_CC_FAT,GO:0005856~cytoskeleton,21,18.42105263,0.010030755,"MYL6, ACTB, ALDOA, VIM, TMSB10, MYL12A, TPM2, TPM1, TPM4, MYL9, ACTG1, PFN1, TUBB, ARPC2, CFL1, TPT1, HSPB1, TMSB4X, TUBA1A, TUBA1B, CALM2",108,1381,12782,1.799702309,0.835454952,0.058378946,11.66748911
GOTERM_BP_FAT,GO:0008064~regulation of actin polymerization or depolymerization,4,3.50877193,0.013055259,"ARPC2, CFL1, TMSB4X, TMSB10",110,61,13528,8.06438152,0.999993762,0.297067293,18.5506821
GOTERM_BP_FAT,GO:0030832~regulation of actin filament length,4,3.50877193,0.014239672,"ARPC2, CFL1, TMSB4X, TMSB10",110,63,13528,7.808369408,0.999997913,0.29778217,20.06358805
GOTERM_BP_FAT,GO:0051130~positive regulation of cellular component organization,6,5.263157895,0.015504172,"TNFRSF12A, ARPC2, CFL1, CD63, CALR, TPM1",110,181,13528,4.076745354,0.999999353,0.299712346,21.64973924
GOTERM_BP_FAT,GO:0051493~regulation of cytoskeleton organization,5,4.385964912,0.024174142,"ARPC2, CFL1, TMSB4X, TMSB10, TPM1",110,136,13528,4.521390374,1,0.391006874,31.75705784
GOTERM_CC_FAT,GO:0044430~cytoskeletal part,15,13.15789474,0.027272661,"MYL6, VIM, MYL12A, TPM2, TPM1, TPM4, MYL9, TUBB, ARPC2, CFL1, TPT1, HSPB1, TUBA1A, TUBA1B, CALM2",108,952,12782,1.864787582,0.992913842,0.128456255,28.84286168
GOTERM_BP_FAT,GO:0051495~positive regulation of cytoskeleton organization,3,2.631578947,0.050885098,"ARPC2, CFL1, TPM1",110,45,13528,8.198787879,1,0.586057892,55.75624126
GOTERM_BP_FAT,GO:0030833~regulation of actin filament polymerization,3,2.631578947,0.070232434,"ARPC2, TMSB4X, TMSB10",110,54,13528,6.832323232,1,0.669409199,67.92307504
GOTERM_BP_FAT,GO:0033043~regulation of organelle organization,5,4.385964912,0.098199831,"ARPC2, CFL1, TMSB4X, TMSB10, TPM1",110,217,13528,2.833682447,1,0.739893324,80.0893576
GOTERM_BP_FAT,GO:0032271~regulation of protein polymerization,3,2.631578947,0.104110109,"ARPC2, TMSB4X, TMSB10",110,68,13528,5.425668449,1,0.737326429,82.03214267
GOTERM_BP_FAT,GO:0010638~positive regulation of organelle organization,3,2.631578947,0.144198887,"ARPC2, CFL1, TPM1",110,83,13528,4.445125958,1,0.800869963,91.20858335
GOTERM_BP_FAT,GO:0043254~regulation of protein complex assembly,3,2.631578947,0.163868815,"ARPC2, TMSB4X, TMSB10",110,90,13528,4.099393939,1,0.823844374,93.88522548
GOTERM_BP_FAT,GO:0032535~regulation of cellular component size,5,4.385964912,0.17512538,"TNFRSF12A, ARPC2, CFL1, TMSB4X, TMSB10",110,271,13528,2.269037236,1,0.836365733,95.05156342
,,,,,,,,,,,,
Annotation Cluster 11,Enrichment Score: 2.1604540605716855,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
SP_PIR_KEYWORDS,calcium binding,8,7.01754386,2.35E-06,"S100A6, S100A11, MYL12A, SPARC, ANXA5, CALR, CALM2, ANXA2",113,103,19235,13.2210671,5.64E-04,5.12E-05,0.00303192
SP_PIR_KEYWORDS,EF hand,5,4.385964912,4.13E-04,"S100A6, S100A11, MYL12A, SPARC, CALM2",113,60,19235,14.18510324,0.094427686,0.004712108,0.532025798
UP_SEQ_FEATURE,domain:EF-hand 2,7,6.140350877,7.13E-04,"MYL6, S100A6, S100A11, FSTL1, MYL12A, CALM2, MYL9",113,182,19113,6.505445882,0.222573414,0.080497045,0.971937176
UP_SEQ_FEATURE,domain:EF-hand 1,7,6.140350877,7.13E-04,"MYL6, S100A6, S100A11, FSTL1, MYL12A, CALM2, MYL9",113,182,19113,6.505445882,0.222573414,0.080497045,0.971937176
INTERPRO,IPR018248:EF hand,6,5.263157895,0.001774022,"MYL6, S100A6, S100A11, MYL12A, CALM2, MYL9",112,130,16659,6.864972527,0.379751962,0.147184406,2.306227804
SP_PIR_KEYWORDS,calcium,13,11.40350877,0.002489994,"S100A6, S100A11, SPARC, MYL12A, CALR, ANXA5, MMP14, MMP1, TPM4, MYL9, ANXA2, TPT1, CALM2",113,803,19235,2.755761029,0.450278703,0.018524518,3.166741613
INTERPRO,IPR018249:EF-HAND 2,7,6.140350877,0.003171429,"MYL6, S100A6, S100A11, FSTL1, MYL12A, CALM2, MYL9",112,215,16659,4.842732558,0.574491372,0.157089092,4.088147329
SMART,SM00054:EFh,5,4.385964912,0.00452283,"MYL6, FSTL1, MYL12A, CALM2, MYL9",44,143,9079,7.214717101,0.154413071,0.080441993,3.988606125
INTERPRO,IPR011992:EF-Hand type,7,6.140350877,0.004991767,"MYL6, S100A6, S100A11, MYL12A, SPARC, CALM2, MYL9",112,236,16659,4.411811441,0.73975919,0.174946331,6.364344399
GOTERM_MF_FAT,GO:0005509~calcium ion binding,16,14.03508772,0.006925268,"MYL6, S100A6, S100A11, FSTL1, SPARC, MYL12A, MMP14, CALR, ANXA5, MMP1, TPM4, ANXA2, MYL9, ANXA2P2, TPT1, CALM2",106,919,12983,2.132424498,0.734814993,0.075107803,8.281491334
INTERPRO,IPR018247:EF-HAND 1,6,5.263157895,0.015075648,"S100A6, S100A11, MYL12A, SPARC, CALM2, MYL9",112,217,16659,4.112656353,0.983197518,0.288599029,18.09507816
INTERPRO,IPR002048:Calcium-binding EF-hand,5,4.385964912,0.015369999,"MYL6, FSTL1, MYL12A, CALM2, MYL9",112,143,16659,5.200736763,0.984495622,0.274221364,18.41614698
UP_SEQ_FEATURE,domain:EF-hand 3,4,3.50877193,0.017855806,"MYL6, MYL12A, CALM2, MYL9",113,94,19113,7.197514592,0.998270723,0.548421694,21.8647854
SP_PIR_KEYWORDS,myosin,3,2.631578947,0.035601404,"MYL6, MYL12A, MYL9",113,51,19235,10.01301406,0.999833438,0.195475238,37.36865746
PIR_SUPERFAMILY,PIRSF002350:calmodulin,3,2.631578947,0.039700205,"MYL12A, CALM2, MYL9",99,24,7396,9.338383838,0.981875052,0.737320859,36.15939491
GOTERM_CC_FAT,GO:0016459~myosin complex,3,2.631578947,0.102883261,"MYL6, MYL12A, MYL9",108,65,12782,5.462393162,0.999999996,0.357044381,73.71195909
SP_PIR_KEYWORDS,motor protein,3,2.631578947,0.179431055,"MYL6, MYL12A, MYL9",113,132,19235,3.868664521,1,0.620388683,92.21173635
KEGG_PATHWAY,hsa04270:Vascular smooth muscle contraction,4,3.50877193,0.240131896,"MYL6, GNAS, CALM2, MYL9",78,112,5085,2.328296703,0.999999908,0.740803247,93.55722675
GOTERM_MF_FAT,GO:0003774~motor activity,3,2.631578947,0.319155379,"MYL6, MYL12A, MYL9",106,142,12983,2.587629551,1,0.862543033,99.16205744
,,,,,,,,,,,,
Annotation Cluster 12,Enrichment Score: 2.105640010463022,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_BP_FAT,GO:0006916~anti-apoptosis,8,7.01754386,0.001377302,"IER3, CCL2, CFL1, TPT1, HSPB1, UBB, ANXA5, GSTP1",110,206,13528,4.775992939,0.715483755,0.080382689,2.12903228
GOTERM_BP_FAT,GO:0043066~negative regulation of apoptosis,9,7.894736842,0.007806563,"IER3, CCL2, CFL1, TPT1, HSPB1, UBB, ANXA5, GSTP1, MIF",110,354,13528,3.126656394,0.999213188,0.225291615,11.518013
GOTERM_BP_FAT,GO:0043069~negative regulation of programmed cell death,9,7.894736842,0.008460764,"IER3, CCL2, CFL1, TPT1, HSPB1, UBB, ANXA5, GSTP1, MIF",110,359,13528,3.083109648,0.999568846,0.234486495,12.42457362
GOTERM_BP_FAT,GO:0060548~negative regulation of cell death,9,7.894736842,0.008596407,"IER3, CCL2, CFL1, TPT1, HSPB1, UBB, ANXA5, GSTP1, MIF",110,360,13528,3.074545455,0.99961942,0.230843262,12.61145074
GOTERM_BP_FAT,GO:0042981~regulation of apoptosis,14,12.28070175,0.012483507,"IER3, TUBB, CCL2, LGALS1, CFL1, TPT1, HSPB1, RPL11, UBB, RPS6, ANXA5, CALR, GSTP1, MIF",110,804,13528,2.141474446,0.999989421,0.293314974,17.81080352
GOTERM_BP_FAT,GO:0043067~regulation of programmed cell death,14,12.28070175,0.013469863,"IER3, TUBB, CCL2, LGALS1, CFL1, TPT1, HSPB1, RPL11, UBB, RPS6, ANXA5, CALR, GSTP1, MIF",110,812,13528,2.120376176,0.999995747,0.29768373,19.08329762
GOTERM_BP_FAT,GO:0010941~regulation of cell death,14,12.28070175,0.013854941,"IER3, TUBB, CCL2, LGALS1, CFL1, TPT1, HSPB1, RPL11, UBB, RPS6, ANXA5, CALR, GSTP1, MIF",110,815,13528,2.11257111,0.999997021,0.297736094,19.57506165
,,,,,,,,,,,,
Annotation Cluster 13,Enrichment Score: 1.9367198574829299,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_MF_FAT,GO:0030246~carbohydrate binding,10,8.771929825,0.002267516,"ALDOA, BSG, BGN, CCL2, CTGF, LGALS1, FSTL1, POSTN, CALR, RPL29",106,354,12983,3.459918985,0.351820294,0.038650283,2.784362486
GOTERM_MF_FAT,GO:0005539~glycosaminoglycan binding,6,5.263157895,0.005536268,"BGN, CCL2, CTGF, FSTL1, POSTN, RPL29",106,140,12983,5.249191375,0.653670668,0.06825025,6.672866377
SP_PIR_KEYWORDS,heparin-binding,4,3.50877193,0.006459253,"CTGF, FSTL1, POSTN, RPL29",113,65,19235,10.47515317,0.788863216,0.043462885,8.024064904
GOTERM_MF_FAT,GO:0001871~pattern binding,6,5.263157895,0.008216274,"BGN, CCL2, CTGF, FSTL1, POSTN, RPL29",106,154,12983,4.771992159,0.79315607,0.083821377,9.753724625
GOTERM_MF_FAT,GO:0030247~polysaccharide binding,6,5.263157895,0.008216274,"BGN, CCL2, CTGF, FSTL1, POSTN, RPL29",106,154,12983,4.771992159,0.79315607,0.083821377,9.753724625
GOTERM_MF_FAT,GO:0008201~heparin binding,5,4.385964912,0.009687099,"CCL2, CTGF, FSTL1, POSTN, RPL29",106,103,12983,5.945686023,0.844211503,0.093220147,11.40451961
GOTERM_BP_FAT,GO:0007167~enzyme linked receptor protein signaling pathway,4,3.50877193,0.522959075,"CCL2, CTGF, COL1A2, FSTL1",110,342,13528,1.438383838,1,0.984498015,99.99904299
,,,,,,,,,,,,
Annotation Cluster 14,Enrichment Score: 1.915035593594391,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_MF_FAT,GO:0019838~growth factor binding,7,6.140350877,2.04E-04,"COL4A1, CTGF, IGFBP7, COL1A2, COL6A1, RPS2, IGFBP2",106,105,12983,8.165408805,0.038239656,0.006477262,0.253611225
SMART,SM00121:IB,3,2.631578947,0.003943912,"CTGF, IGFBP7, IGFBP2",44,20,9079,30.95113636,0.136026564,0.136026564,3.486087486
UP_SEQ_FEATURE,domain:IGFBP N-terminal,3,2.631578947,0.006035579,"CTGF, IGFBP7, IGFBP2",113,20,19113,25.37123894,0.881993433,0.299645867,7.955912866
INTERPRO,"IPR000867:Insulin-like growth factor-binding protein, IGFBP",3,2.631578947,0.007729777,"CTGF, IGFBP7, IGFBP2",112,20,16659,22.31116071,0.875989363,0.229660145,9.694182489
GOTERM_MF_FAT,GO:0005520~insulin-like growth factor binding,3,2.631578947,0.017218958,"CTGF, IGFBP7, IGFBP2",106,25,12983,14.69773585,0.963755413,0.146128474,19.43125349
GOTERM_BP_FAT,GO:0001558~regulation of cell growth,4,3.50877193,0.205870585,"TNFRSF12A, CTGF, IGFBP7, IGFBP2",110,194,13528,2.535707591,1,0.867528164,97.26544571
GOTERM_BP_FAT,GO:0040008~regulation of growth,5,4.385964912,0.295434519,"TNFRSF12A, CTGF, IGFBP7, UBB, IGFBP2",110,341,13528,1.803252466,1,0.928590762,99.57789554
,,,,,,,,,,,,
Annotation Cluster 15,Enrichment Score: 1.8934690881506302,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_CC_FAT,GO:0001726~ruffle,6,5.263157895,2.39E-04,"S100A6, TNFRSF12A, S100A11, GNAS, TPM1, ITGB1",108,67,12782,10.5986733,0.041936641,0.002377246,0.294095645
GOTERM_CC_FAT,GO:0031252~cell leading edge,7,6.140350877,0.001051322,"S100A6, TNFRSF12A, ARPC2, S100A11, GNAS, TPM1, ITGB1",108,138,12782,6.003354804,0.171621996,0.008925911,1.286098465
GOTERM_CC_FAT,GO:0042995~cell projection,10,8.771929825,0.129292807,"ACTB, S100A6, TNFRSF12A, ARPC2, VIM, UCHL1, S100A11, GNAS, TPM1, ITGB1",108,697,12782,1.698017961,1,0.416522429,81.80026429
GOTERM_MF_FAT,GO:0046983~protein dimerization activity,4,3.50877193,0.820077797,"S100A6, LGALS1, S100A11, ITGB1",106,542,12983,0.903919794,1,0.99941603,99.99999995
,,,,,,,,,,,,
Annotation Cluster 16,Enrichment Score: 1.8146504211396504,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
SP_PIR_KEYWORDS,methylated amino acid,3,2.631578947,0.005961859,"ACTG1, ACTB, CALM2",113,20,19235,25.53318584,0.761915219,0.041331235,7.42795516
GOTERM_BP_FAT,GO:0010035~response to inorganic substance,7,6.140350877,0.006262217,"ACTG1, ACTB, BSG, SERPINE1, IGFBP2, TPM1, CALM2",110,205,13528,4.199379157,0.996749995,0.212358664,9.342968956
GOTERM_BP_FAT,GO:0010038~response to metal ion,5,4.385964912,0.020365033,"ACTG1, ACTB, BSG, IGFBP2, CALM2",110,129,13528,4.766737139,0.999999993,0.360313499,27.47692352
GOTERM_BP_FAT,GO:0051592~response to calcium ion,3,2.631578947,0.072510918,"ACTG1, ACTB, CALM2",110,55,13528,6.708099174,1,0.669536815,69.1287301
,,,,,,,,,,,,
Annotation Cluster 17,Enrichment Score: 1.6741962114053153,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_BP_FAT,GO:0001568~blood vessel development,7,6.140350877,0.014292538,"BGN, TNFRSF12A, CTGF, COL1A2, MMP14, ANXA2P2, ANXA2",110,245,13528,3.513766234,0.999998013,0.292130732,20.13050012
GOTERM_BP_FAT,GO:0001944~vasculature development,7,6.140350877,0.01592742,"BGN, TNFRSF12A, CTGF, COL1A2, MMP14, ANXA2P2, ANXA2",110,251,13528,3.429771822,0.999999563,0.300325278,22.17403494
GOTERM_BP_FAT,GO:0048514~blood vessel morphogenesis,6,5.263157895,0.027898622,"BGN, TNFRSF12A, CTGF, MMP14, ANXA2P2, ANXA2",110,211,13528,3.497113313,1,0.429352001,35.71253142
GOTERM_BP_FAT,GO:0001525~angiogenesis,5,4.385964912,0.031650285,"TNFRSF12A, CTGF, MMP14, ANXA2P2, ANXA2",110,148,13528,4.154791155,1,0.457234349,39.47915213
,,,,,,,,,,,,
Annotation Cluster 18,Enrichment Score: 1.661169857855445,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_CC_FAT,GO:0005730~nucleolus,14,12.28070175,0.005445878,"UCHL1, RPL35, RPS9, RPL36, RPS2, RPS6, RPS25, RPS19, RPL23, RPS14, RPL3, RPS13, RPL11, RPL5",108,698,12782,2.373819378,0.623740458,0.035555334,6.499204513
GOTERM_CC_FAT,GO:0043233~organelle lumen,25,21.92982456,0.014412178,"ACTB, P4HB, PSAP, UCHL1, RPL35, RPL36, RPS9, SPARC, RPS6, CALR, RPS2, SERPINH1, TIMP1, RPS25, RPS19, RPL23, PPIB, RPS14, CFL1, RPL3, RPS13, RPL5, RPL11, UBB, CALM2",108,1820,12782,1.625712251,0.925618691,0.075723452,16.35989498
GOTERM_CC_FAT,GO:0031974~membrane-enclosed lumen,25,21.92982456,0.018007143,"ACTB, P4HB, PSAP, UCHL1, RPL35, RPL36, RPS9, SPARC, RPS6, CALR, RPS2, SERPINH1, TIMP1, RPS25, RPS19, RPL23, PPIB, RPS14, CFL1, RPL3, RPS13, RPL5, RPL11, UBB, CALM2",108,1856,12782,1.594179039,0.961328518,0.091232743,20.03776746
GOTERM_CC_FAT,GO:0070013~intracellular organelle lumen,23,20.1754386,0.036893134,"ACTB, P4HB, PSAP, UCHL1, RPL35, RPS9, RPL36, RPS2, RPS6, CALR, SERPINH1, RPS25, RPS19, PPIB, RPL23, RPS14, CFL1, RPL3, RPS13, RPL5, RPL11, UBB, CALM2",108,1779,12782,1.530125122,0.998803998,0.162281311,37.03520895
GOTERM_CC_FAT,GO:0031981~nuclear lumen,18,15.78947368,0.094833734,"ACTB, UCHL1, RPL35, RPS9, RPL36, RPS2, RPS6, RPS25, RPS19, RPL23, RPS14, CFL1, RPL3, RPS13, RPL5, RPL11, UBB, CALM2",108,1450,12782,1.469195402,0.999999982,0.339505479,70.65742601
,,,,,,,,,,,,
Annotation Cluster 19,Enrichment Score: 1.5882632596315507,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
SMART,SM00280:KAZAL,3,2.631578947,0.019878022,"IGFBP7, FSTL1, SPARC",44,46,9079,13.45701581,0.524265413,0.219352616,16.49684065
UP_SEQ_FEATURE,domain:Kazal-like,3,2.631578947,0.022965654,"IGFBP7, FSTL1, SPARC",113,40,19113,12.68561947,0.999725735,0.597986029,27.25154291
INTERPRO,"IPR002350:Proteinase inhibitor I1, Kazal",3,2.631578947,0.037649415,"IGFBP7, FSTL1, SPARC",112,46,16659,9.700504658,0.99996714,0.497529264,39.60649963
,,,,,,,,,,,,
Annotation Cluster 20,Enrichment Score: 1.5179769170187563,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
KEGG_PATHWAY,hsa05414:Dilated cardiomyopathy,7,6.140350877,0.002515777,"ACTG1, ACTB, GNAS, TPM2, TPM1, ITGB1, TPM4",78,92,5085,4.960284281,0.138101603,0.048332238,2.484004241
GOTERM_BP_FAT,GO:0045214~sarcomere organization,3,2.631578947,0.004027707,"ACTG1, TPM1, ITGB1",110,12,13528,30.74545455,0.974794327,0.168092739,6.107178408
KEGG_PATHWAY,hsa05410:Hypertrophic cardiomyopathy (HCM),6,5.263157895,0.008927541,"ACTG1, ACTB, TPM2, TPM1, ITGB1, TPM4",78,85,5085,4.601809955,0.410859262,0.084405499,8.565669731
GOTERM_BP_FAT,GO:0030239~myofibril assembly,3,2.631578947,0.01222484,"ACTG1, TPM1, ITGB1",110,21,13528,17.56883117,0.999986567,0.295702951,17.47401184
GOTERM_BP_FAT,GO:0031032~actomyosin structure organization,3,2.631578947,0.02121579,"ACTG1, TPM1, ITGB1",110,28,13528,13.17662338,0.999999997,0.36543399,28.45412035
GOTERM_BP_FAT,GO:0010927~cellular component assembly involved in morphogenesis,3,2.631578947,0.033921352,"ACTG1, TPM1, ITGB1",110,36,13528,10.24848485,1,0.47392378,41.65783644
GOTERM_BP_FAT,GO:0032989~cellular component morphogenesis,8,7.01754386,0.041355898,"ACTG1, ACTB, S100A6, UCHL1, CFL1, UBB, TPM1, ITGB1",110,397,13528,2.478223036,1,0.537159811,48.28746864
GOTERM_BP_FAT,GO:0055002~striated muscle cell development,3,2.631578947,0.065748881,"ACTG1, TPM1, ITGB1",110,52,13528,7.095104895,1,0.656785211,65.42084583
GOTERM_BP_FAT,GO:0042692~muscle cell differentiation,4,3.50877193,0.074173495,"ACTG1, LGALS1, TPM1, ITGB1",110,121,13528,4.065514651,1,0.672300138,69.9815681
GOTERM_BP_FAT,GO:0055001~muscle cell development,3,2.631578947,0.074813166,"ACTG1, TPM1, ITGB1",110,56,13528,6.588311688,1,0.669805696,70.3037806
GOTERM_BP_FAT,GO:0051146~striated muscle cell differentiation,3,2.631578947,0.158198576,"ACTG1, TPM1, ITGB1",110,88,13528,4.192561983,1,0.815255247,93.20465259
KEGG_PATHWAY,hsa05412:Arrhythmogenic right ventricular cardiomyopathy (ARVC),3,2.631578947,0.320320236,"ACTG1, ACTB, ITGB1",78,76,5085,2.573380567,1,0.826651657,97.88446258
,,,,,,,,,,,,
Annotation Cluster 21,Enrichment Score: 1.4900007277767384,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_BP_FAT,GO:0050819~negative regulation of coagulation,4,3.50877193,0.001155942,"SERPINE1, ANXA5, ANXA2P2, ANXA2",110,26,13528,18.92027972,0.651748128,0.072576483,1.789741361
GOTERM_BP_FAT,GO:0042730~fibrinolysis,3,2.631578947,0.004027707,"SERPINE1, ANXA2P2, ANXA2",110,12,13528,30.74545455,0.974794327,0.168092739,6.107178408
GOTERM_MF_FAT,GO:0004859~phospholipase inhibitor activity,3,2.631578947,0.004055823,"ANXA5, ANXA2P2, ANXA2",106,12,12983,30.62028302,0.53986598,0.057962857,4.929805435
GOTERM_BP_FAT,GO:0050818~regulation of coagulation,4,3.50877193,0.004342235,"SERPINE1, ANXA5, ANXA2P2, ANXA2",110,41,13528,11.99822616,0.981102797,0.172203299,6.569092679
GOTERM_MF_FAT,GO:0055102~lipase inhibitor activity,3,2.631578947,0.006351273,"ANXA5, ANXA2P2, ANXA2",106,15,12983,24.49622642,0.703871496,0.073239504,7.619854155
GOTERM_BP_FAT,GO:0030195~negative regulation of blood coagulation,3,2.631578947,0.01457494,"SERPINE1, ANXA2P2, ANXA2",110,23,13528,16.04110672,0.99999847,0.290601291,20.48704159
GOTERM_MF_FAT,GO:0005544~calcium-dependent phospholipid binding,3,2.631578947,0.018556595,"ANXA5, ANXA2P2, ANXA2",106,26,12983,14.13243832,0.972057528,0.150084649,20.78479124
GOTERM_MF_FAT,GO:0004857~enzyme inhibitor activity,7,6.140350877,0.022259236,"OAZ1, SERPINE1, ANXA5, SERPINH1, ANXA2P2, TIMP1, ANXA2",106,270,12983,3.175436758,0.986425279,0.164017625,24.42315079
GOTERM_BP_FAT,GO:0030193~regulation of blood coagulation,3,2.631578947,0.033921352,"SERPINE1, ANXA2P2, ANXA2",110,36,13528,10.24848485,1,0.47392378,41.65783644
GOTERM_BP_FAT,GO:0050878~regulation of body fluid levels,4,3.50877193,0.105280636,"SERPINE1, ANXA5, ANXA2P2, ANXA2",110,141,13528,3.488845906,1,0.736826569,82.39522095
GOTERM_BP_FAT,GO:0051241~negative regulation of multicellular organismal process,4,3.50877193,0.146220744,"SERPINE1, ANXA5, ANXA2P2, ANXA2",110,164,13528,2.999556541,1,0.802082025,91.52735028
GOTERM_MF_FAT,GO:0019899~enzyme binding,7,6.140350877,0.248528808,"ACTB, PFN1, VIM, SERPINE1, GNB2L1, ANXA2P2, ANXA2",106,523,12983,1.639326816,1,0.780393086,97.1396343
GOTERM_BP_FAT,GO:0032101~regulation of response to external stimulus,3,2.631578947,0.367452825,"SERPINE1, ANXA2P2, ANXA2",110,159,13528,2.320411664,1,0.951528814,99.92161496
GOTERM_MF_FAT,GO:0005543~phospholipid binding,3,2.631578947,0.420584763,"ANXA5, ANXA2P2, ANXA2",106,177,12983,2.075951391,1,0.926162526,99.88734974
GOTERM_MF_FAT,GO:0008289~lipid binding,4,3.50877193,0.710336308,"PSAP, ANXA5, ANXA2P2, ANXA2",106,450,12983,1.088721174,1,0.996428101,99.99997976
,,,,,,,,,,,,
Annotation Cluster 22,Enrichment Score: 1.4482419522060055,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
KEGG_PATHWAY,hsa04510:Focal adhesion,10,8.771929825,0.003084545,"ACTG1, ACTB, COL4A2, COL4A1, COL1A2, COL6A2, COL6A1, MYL12A, ITGB1, MYL9",78,201,5085,3.243398393,0.166623187,0.044544745,3.037833582
KEGG_PATHWAY,hsa04810:Regulation of actin cytoskeleton,9,7.894736842,0.015331044,"ACTG1, ACTB, PFN1, ARPC2, CFL1, TMSB4X, MYL12A, ITGB1, MYL9",78,215,5085,2.728980322,0.598093979,0.122097352,14.2966931
KEGG_PATHWAY,hsa04670:Leukocyte transendothelial migration,5,4.385964912,0.102815534,"ACTG1, ACTB, MYL12A, ITGB1, MYL9",78,118,5085,2.762385919,0.998340325,0.550734703,66.15570902
KEGG_PATHWAY,hsa04530:Tight junction,4,3.50877193,0.331291793,"ACTG1, ACTB, MYL12A, MYL9",78,134,5085,1.946039036,1,0.816558613,98.20177496
,,,,,,,,,,,,
Annotation Cluster 23,Enrichment Score: 1.277741887578586,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
SP_PIR_KEYWORDS,cell adhesion,8,7.01754386,0.011765454,"TNFRSF12A, CTGF, IGFBP7, TGFBI, COL6A2, COL6A1, POSTN, ITGB1",113,422,19235,3.226942918,0.94160071,0.07586899,14.16668731
GOTERM_BP_FAT,GO:0007155~cell adhesion,10,8.771929825,0.111348617,"CCL2, TNFRSF12A, CTGF, IGFBP7, TGFBI, COL6A2, COL6A1, POSTN, CD151, ITGB1",110,700,13528,1.756883117,1,0.739661617,84.1698784
GOTERM_BP_FAT,GO:0022610~biological adhesion,10,8.771929825,0.112067792,"CCL2, TNFRSF12A, CTGF, IGFBP7, TGFBI, COL6A2, COL6A1, POSTN, CD151, ITGB1",110,701,13528,1.754376864,1,0.733386119,84.36873501
,,,,,,,,,,,,
Annotation Cluster 24,Enrichment Score: 1.2167651489012508,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_BP_FAT,GO:0001501~skeletal system development,7,6.140350877,0.044125494,"CTGF, COL1A2, GNAS, POSTN, SPARC, MMP14, ANXA2",110,319,13528,2.698660587,1,0.55380819,50.57164021
GOTERM_BP_FAT,GO:0001503~ossification,4,3.50877193,0.065784488,"CTGF, GNAS, SPARC, MMP14",110,115,13528,4.277628458,1,0.650713427,65.4414183
GOTERM_BP_FAT,GO:0060348~bone development,4,3.50877193,0.077071085,"CTGF, GNAS, SPARC, MMP14",110,123,13528,3.999408721,1,0.675448373,71.41543733
,,,,,,,,,,,,
Annotation Cluster 25,Enrichment Score: 1.2152839341440456,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
SP_PIR_KEYWORDS,actin binding,5,4.385964912,8.47E-05,"PFN1, TAGLN, CFL1, TPM1, ANXA2",113,40,19235,21.27765487,0.020120112,0.001128545,0.109252132
GOTERM_BP_FAT,GO:0048729~tissue morphogenesis,4,3.50877193,0.177309192,"PFN1, CFL1, COL1A2, TPM1",110,180,13528,2.732929293,1,0.837377049,95.25221027
GOTERM_BP_FAT,GO:0043009~chordate embryonic development,5,4.385964912,0.277396518,"PFN1, CFL1, GNAS, TPM1, ITGB1",110,331,13528,1.857731392,1,0.920540838,99.37361274
GOTERM_BP_FAT,GO:0009792~embryonic development ending in birth or egg hatching,5,4.385964912,0.282789065,"PFN1, CFL1, GNAS, TPM1, ITGB1",110,334,13528,1.841045182,1,0.921711627,99.44275299
GOTERM_BP_FAT,GO:0048598~embryonic morphogenesis,3,2.631578947,0.71199772,"PFN1, CFL1, GNAS",110,307,13528,1.201776725,1,0.998477068,99.99999964
,,,,,,,,,,,,
Annotation Cluster 26,Enrichment Score: 1.135743871379696,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_BP_FAT,GO:0006928~cell motion,15,13.15789474,2.70E-05,"ACTB, CCL2, TNFRSF12A, VIM, MMP14, TPM1, ITGB1, TPM4, ACTG1, TUBB, CTGF, ARPC2, CFL1, HSPB1, UBB",110,475,13528,3.883636364,0.024339134,0.00307529,0.042177113
GOTERM_BP_FAT,GO:0016477~cell migration,6,5.263157895,0.072283661,"CCL2, TNFRSF12A, CTGF, CFL1, MMP14, ITGB1",110,276,13528,2.673517787,1,0.67429036,69.01040997
GOTERM_BP_FAT,GO:0048870~cell motility,6,5.263157895,0.102188569,"CCL2, TNFRSF12A, CTGF, CFL1, MMP14, ITGB1",110,307,13528,2.40355345,1,0.735126588,81.42087846
GOTERM_BP_FAT,GO:0051674~localization of cell,6,5.263157895,0.102188569,"CCL2, TNFRSF12A, CTGF, CFL1, MMP14, ITGB1",110,307,13528,2.40355345,1,0.735126588,81.42087846
GOTERM_BP_FAT,GO:0031589~cell-substrate adhesion,3,2.631578947,0.186885975,"TNFRSF12A, CTGF, ITGB1",110,98,13528,3.764749536,1,0.851302288,96.04551011
GOTERM_BP_FAT,GO:0035295~tube development,4,3.50877193,0.26128526,"PFN1, CTGF, CFL1, MMP14",110,220,13528,2.236033058,1,0.911322362,99.11615671
GOTERM_BP_FAT,GO:0048609~reproductive process in a multicellular organism,3,2.631578947,0.907683252,"CCL2, MMP14, ITGB1",110,487,13528,0.757588202,1,0.999986331,100
GOTERM_BP_FAT,GO:0032504~multicellular organism reproduction,3,2.631578947,0.907683252,"CCL2, MMP14, ITGB1",110,487,13528,0.757588202,1,0.999986331,100
,,,,,,,,,,,,
Annotation Cluster 27,Enrichment Score: 1.0873690249877905,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_MF_FAT,GO:0005200~structural constituent of cytoskeleton,7,6.140350877,2.88E-05,"ACTG1, ACTB, TUBB, ARPC2, VIM, TPM1, TUBA1B",106,74,12983,11.58605303,0.005477469,0.001097902,0.035765236
KEGG_PATHWAY,hsa05130:Pathogenic Escherichia coli infection,7,6.140350877,1.95E-04,"ACTG1, ACTB, TUBB, ARPC2, TUBA1A, ITGB1, TUBA1B",78,57,5085,8.006072874,0.01141797,0.005725375,0.194173534
SP_PIR_KEYWORDS,methylation,8,7.01754386,5.41E-04,"ACTG1, ACTB, EEF1A1, TUBB, GAPDH, TUBA1B, CALM2, RPL29",113,242,19235,5.627148395,0.121693868,0.00539208,0.6954363
INTERPRO,"IPR018316:Tubulin/FtsZ, 2-layer sandwich domain",3,2.631578947,0.009316731,"TUBB, TUBA1A, TUBA1B",112,22,16659,20.28287338,0.919375161,0.244043962,11.57372782
INTERPRO,"IPR017975:Tubulin, conserved site",3,2.631578947,0.010159976,"TUBB, TUBA1A, TUBA1B",112,23,16659,19.40100932,0.935880843,0.24020089,12.55767517
INTERPRO,IPR000217:Tubulin,3,2.631578947,0.011035774,"TUBB, TUBA1A, TUBA1B",112,24,16659,18.59263393,0.949466828,0.237669451,13.56889092
INTERPRO,"IPR003008:Tubulin/FtsZ, GTPase domain",3,2.631578947,0.011035774,"TUBB, TUBA1A, TUBA1B",112,24,16659,18.59263393,0.949466828,0.237669451,13.56889092
GOTERM_MF_FAT,GO:0003924~GTPase activity,6,5.263157895,0.02824413,"EEF1A1, TUBB, EEF2, GNAS, TUBA1A, TUBA1B",106,211,12983,3.482875794,0.995798349,0.196590804,29.98058855
UP_SEQ_FEATURE,nucleotide phosphate-binding region:GTP,6,5.263157895,0.029878207,"EEF1A1, TUBB, EEF2, GNAS, TUBA1A, TUBA1B",113,295,19113,3.440167992,0.99997763,0.657258251,33.99194452
PIR_SUPERFAMILY,PIRSF002306:tubulin,3,2.631578947,0.033797848,"TUBB, TUBA1A, TUBA1B",99,22,7396,10.18732782,0.966754563,0.817666687,31.67521521
SP_PIR_KEYWORDS,gtp-binding,6,5.263157895,0.043385294,"EEF1A1, TUBB, EEF2, GNAS, TUBA1A, TUBA1B",113,329,19235,3.104338704,0.999976183,0.22388511,43.5890292
SP_PIR_KEYWORDS,GTP binding,3,2.631578947,0.058167359,"EEF1A1, EEF2, GNAS",113,67,19235,7.62184652,0.999999433,0.273570842,53.86121989
GOTERM_BP_FAT,GO:0051258~protein polymerization,3,2.631578947,0.05921524,"TUBB, TUBA1A, TUBA1B",110,49,13528,7.529499072,1,0.62994168,61.44569182
GOTERM_BP_FAT,GO:0007018~microtubule-based movement,4,3.50877193,0.063091748,"TUBB, UCHL1, TUBA1A, TUBA1B",110,113,13528,4.353338697,1,0.647504949,63.85290076
GOTERM_BP_FAT,GO:0043623~cellular protein complex assembly,4,3.50877193,0.142471602,"TUBB, TUBA1A, CALR, TUBA1B",110,162,13528,3.036588103,1,0.800354166,90.92740292
KEGG_PATHWAY,hsa04540:Gap junction,4,3.50877193,0.151415871,"TUBB, GNAS, TUBA1A, TUBA1B",78,89,5085,2.929991357,0.999937913,0.659156131,80.59293351
GOTERM_MF_FAT,GO:0005525~GTP binding,6,5.263157895,0.18301384,"EEF1A1, TUBB, EEF2, GNAS, TUBA1A, TUBA1B",106,372,12983,1.97550213,1,0.735863846,91.90900623
GOTERM_MF_FAT,GO:0019001~guanyl nucleotide binding,6,5.263157895,0.196933158,"EEF1A1, TUBB, EEF2, GNAS, TUBA1A, TUBA1B",106,382,12983,1.923787415,1,0.741090768,93.46619127
GOTERM_MF_FAT,GO:0032561~guanyl ribonucleotide binding,6,5.263157895,0.196933158,"EEF1A1, TUBB, EEF2, GNAS, TUBA1A, TUBA1B",106,382,12983,1.923787415,1,0.741090768,93.46619127
GOTERM_BP_FAT,GO:0034622~cellular macromolecular complex assembly,5,4.385964912,0.254254153,"TUBB, RPS14, TUBA1A, CALR, TUBA1B",110,318,13528,1.933676387,1,0.908267033,98.97526127
GOTERM_BP_FAT,GO:0034621~cellular macromolecular complex subunit organization,5,4.385964912,0.324593825,"TUBB, RPS14, TUBA1A, CALR, TUBA1B",110,357,13528,1.722434428,1,0.93761727,99.7818269
GOTERM_BP_FAT,GO:0007017~microtubule-based process,4,3.50877193,0.333858037,"TUBB, UCHL1, TUBA1A, TUBA1B",110,253,13528,1.944376572,1,0.942156683,99.82414942
GOTERM_BP_FAT,GO:0006461~protein complex assembly,6,5.263157895,0.384894475,"TUBB, TUBA1A, ANXA5, CALR, TUBA1B, MIF",110,505,13528,1.461170117,1,0.956857209,99.94934458
GOTERM_BP_FAT,GO:0070271~protein complex biogenesis,6,5.263157895,0.384894475,"TUBB, TUBA1A, ANXA5, CALR, TUBA1B, MIF",110,505,13528,1.461170117,1,0.956857209,99.94934458
SP_PIR_KEYWORDS,microtubule,3,2.631578947,0.390123188,"TUBB, TUBA1A, TUBA1B",113,231,19235,2.210665441,1,0.884422124,99.83095069
GOTERM_CC_FAT,GO:0005874~microtubule,4,3.50877193,0.403434607,"TUBB, TUBA1A, TUBA1B, CALM2",108,274,12782,1.727764261,1,0.825290375,99.8265226
GOTERM_BP_FAT,GO:0065003~macromolecular complex assembly,7,6.140350877,0.448395141,"TUBB, RPS14, TUBA1A, ANXA5, CALR, TUBA1B, MIF",110,665,13528,1.294545455,1,0.974421778,99.99075856
GOTERM_BP_FAT,GO:0043933~macromolecular complex subunit organization,7,6.140350877,0.51220723,"TUBB, RPS14, TUBA1A, ANXA5, CALR, TUBA1B, MIF",110,710,13528,1.212496799,1,0.984134742,99.99864463
GOTERM_CC_FAT,GO:0015630~microtubule cytoskeleton,5,4.385964912,0.680410078,"TUBB, HSPB1, TUBA1A, TUBA1B, CALM2",108,549,12782,1.077885718,1,0.968595942,99.99991992
SP_PIR_KEYWORDS,nucleotide-binding,9,7.894736842,0.775880243,"ACTG1, ACTB, EEF1A1, TUBB, PKM2, EEF2, GNAS, TUBA1A, TUBA1B",113,1686,19235,0.9086543,1,0.998158467,99.99999959
GOTERM_MF_FAT,GO:0032553~ribonucleotide binding,9,7.894736842,0.986545962,"ACTG1, ACTB, EEF1A1, TUBB, PKM2, EEF2, GNAS, TUBA1A, TUBA1B",106,1836,12983,0.600397706,1,0.999999975,100
GOTERM_MF_FAT,GO:0032555~purine ribonucleotide binding,9,7.894736842,0.986545962,"ACTG1, ACTB, EEF1A1, TUBB, PKM2, EEF2, GNAS, TUBA1A, TUBA1B",106,1836,12983,0.600397706,1,0.999999975,100
GOTERM_MF_FAT,GO:0017076~purine nucleotide binding,9,7.894736842,0.991408716,"ACTG1, ACTB, EEF1A1, TUBB, PKM2, EEF2, GNAS, TUBA1A, TUBA1B",106,1918,12983,0.574728983,1,0.999999994,100
GOTERM_MF_FAT,GO:0000166~nucleotide binding,11,9.649122807,0.991634591,"ACTG1, ACTB, EEF1A1, TUBB, PKM2, EEF2, GNAS, TUBA1A, GAPDH, TUBA1B, RPS24",106,2245,12983,0.600130269,1,0.999999992,100
,,,,,,,,,,,,
Annotation Cluster 28,Enrichment Score: 0.9951379164789087,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_BP_FAT,GO:0034101~erythrocyte homeostasis,4,3.50877193,0.007163976,"RPS19, RPS14, RPS24, TIMP1",110,49,13528,10.0393321,0.998579948,0.222906571,10.61900162
GOTERM_BP_FAT,GO:0030218~erythrocyte differentiation,3,2.631578947,0.046893935,"RPS19, RPS14, TIMP1",110,43,13528,8.58012685,1,0.569305506,52.760217
GOTERM_BP_FAT,GO:0048872~homeostasis of number of cells,4,3.50877193,0.046906707,"RPS19, RPS14, RPS24, TIMP1",110,100,13528,4.919272727,1,0.562506464,52.77010044
GOTERM_BP_FAT,GO:0030099~myeloid cell differentiation,3,2.631578947,0.172441184,"RPS19, RPS14, TIMP1",110,93,13528,3.967155425,1,0.837494095,94.79406836
GOTERM_BP_FAT,GO:0030097~hemopoiesis,4,3.50877193,0.296323046,"RPS19, RPS14, ITGB1, TIMP1",110,236,13528,2.084437596,1,0.927714187,99.58613106
GOTERM_BP_FAT,GO:0048534~hemopoietic or lymphoid organ development,4,3.50877193,0.349319417,"RPS19, RPS14, ITGB1, TIMP1",110,260,13528,1.892027972,1,0.946323135,99.87813027
GOTERM_BP_FAT,GO:0002520~immune system development,4,3.50877193,0.384502933,"RPS19, RPS14, ITGB1, TIMP1",110,276,13528,1.782345191,1,0.957639813,99.94883876
,,,,,,,,,,,,
Annotation Cluster 29,Enrichment Score: 0.9643647871216278,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_BP_FAT,GO:0032989~cellular component morphogenesis,8,7.01754386,0.041355898,"ACTG1, ACTB, S100A6, UCHL1, CFL1, UBB, TPM1, ITGB1",110,397,13528,2.478223036,1,0.537159811,48.28746864
GOTERM_CC_FAT,GO:0030863~cortical cytoskeleton,3,2.631578947,0.063312363,"ACTG1, ACTB, CFL1",108,49,12782,7.246031746,0.999991769,0.243272195,55.28586728
GOTERM_CC_FAT,GO:0044448~cell cortex part,3,2.631578947,0.153195261,"ACTG1, ACTB, CFL1",108,83,12782,4.277777778,1,0.469162185,87.07890296
GOTERM_CC_FAT,GO:0005938~cell cortex,3,2.631578947,0.346154149,"ACTG1, ACTB, CFL1",108,146,12782,2.431887367,1,0.774910758,99.46391247
,,,,,,,,,,,,
Annotation Cluster 30,Enrichment Score: 0.879448172091426,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
KEGG_PATHWAY,hsa04512:ECM-receptor interaction,6,5.263157895,0.008501071,"COL4A2, COL4A1, COL1A2, COL6A2, COL6A1, ITGB1",78,84,5085,4.656593407,0.395713756,0.09583323,8.172014858
KEGG_PATHWAY,hsa05222:Small cell lung cancer,3,2.631578947,0.36471951,"COL4A2, COL4A1, ITGB1",78,84,5085,2.328296703,1,0.8123125,98.92242275
KEGG_PATHWAY,hsa05200:Pathways in cancer,5,4.385964912,0.741690693,"COL4A2, COL4A1, ITGB1, MMP1, GSTP1",78,328,5085,0.993785178,1,0.988166159,99.99986519
,,,,,,,,,,,,
Annotation Cluster 31,Enrichment Score: 0.8634617920536498,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_MF_FAT,GO:0004857~enzyme inhibitor activity,7,6.140350877,0.022259236,"OAZ1, SERPINE1, ANXA5, SERPINH1, ANXA2P2, TIMP1, ANXA2",106,270,12983,3.175436758,0.986425279,0.164017625,24.42315079
GOTERM_MF_FAT,GO:0004866~endopeptidase inhibitor activity,3,2.631578947,0.3280674,"SERPINE1, SERPINH1, TIMP1",106,145,12983,2.534092388,1,0.864454688,99.28873378
GOTERM_MF_FAT,GO:0030414~peptidase inhibitor activity,3,2.631578947,0.351674831,"SERPINE1, SERPINH1, TIMP1",106,153,12983,2.401590825,1,0.880252156,99.54415961
,,,,,,,,,,,,
Annotation Cluster 32,Enrichment Score: 0.8605983444457701,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
UP_SEQ_FEATURE,short sequence motif:Prevents secretion from ER,4,3.50877193,0.005017367,"P4HB, PPIB, CALR, SERPINH1",113,59,19113,11.46722664,0.830616311,0.29890912,6.656270458
GOTERM_CC_FAT,GO:0005788~endoplasmic reticulum lumen,4,3.50877193,0.029440556,"P4HB, PPIB, CALR, SERPINH1",108,80,12782,5.917592593,0.995247053,0.134603337,30.77002828
INTERPRO,"IPR000886:Endoplasmic reticulum, targeting sequence",3,2.631578947,0.036166769,"P4HB, CALR, SERPINH1",112,45,16659,9.916071429,0.999950282,0.507271303,38.3723306
SP_PIR_KEYWORDS,Chaperone,3,2.631578947,0.234620077,"P4HB, CALR, SERPINH1",113,158,19235,3.232048841,1,0.715855579,96.82938419
GOTERM_MF_FAT,GO:0051082~unfolded protein binding,3,2.631578947,0.238296954,"PPIB, CALR, SERPINH1",106,115,12983,3.195159967,1,0.773594155,96.61559217
GOTERM_CC_FAT,GO:0044432~endoplasmic reticulum part,4,3.50877193,0.55888713,"P4HB, PPIB, CALR, SERPINH1",108,347,12782,1.364286477,1,0.9200153,99.99577506
SP_PIR_KEYWORDS,endoplasmic reticulum,4,3.50877193,0.789610649,"P4HB, PPIB, CALR, SERPINH1",113,713,19235,0.954957862,1,0.998237219,99.99999982
GOTERM_CC_FAT,GO:0005783~endoplasmic reticulum,4,3.50877193,0.989147038,"P4HB, PPIB, CALR, SERPINH1",108,960,12782,0.493132716,1,0.999990524,100
,,,,,,,,,,,,
Annotation Cluster 33,Enrichment Score: 0.8258336785276674,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_BP_FAT,GO:0007565~female pregnancy,5,4.385964912,0.011984531,"BSG, IGFBP7, GNAS, IGFBP2, RPL29",110,110,13528,5.590082645,0.99998323,0.29862103,17.15996528
GOTERM_BP_FAT,GO:0010033~response to organic substance,12,10.52631579,0.030603634,"BSG, CCL2, IGFBP7, CFL1, COL6A2, HSPB1, GNAS, MMP14, ANXA5, IGFBP2, SERPINH1, B2M",110,721,13528,2.046854117,1,0.452896526,38.44965203
GOTERM_BP_FAT,GO:0009612~response to mechanical stimulus,3,2.631578947,0.074813166,"CCL2, MMP14, IGFBP2",110,56,13528,6.588311688,1,0.669805696,70.3037806
GOTERM_BP_FAT,GO:0033273~response to vitamin,3,2.631578947,0.09903097,"CCL2, IGFBP7, IGFBP2",110,66,13528,5.590082645,1,0.733114531,80.3739642
GOTERM_BP_FAT,GO:0009719~response to endogenous stimulus,7,6.140350877,0.108770372,"BSG, CCL2, IGFBP7, CFL1, GNAS, MMP14, IGFBP2",110,405,13528,2.125611672,1,0.739826416,83.43734715
GOTERM_BP_FAT,GO:0051384~response to glucocorticoid stimulus,3,2.631578947,0.130485814,"CCL2, IGFBP7, IGFBP2",110,78,13528,4.73006993,1,0.776912925,88.73175482
GOTERM_BP_FAT,GO:0031960~response to corticosteroid stimulus,3,2.631578947,0.149766884,"CCL2, IGFBP7, IGFBP2",110,85,13528,4.340534759,1,0.803287685,92.06045946
GOTERM_BP_FAT,GO:0009725~response to hormone stimulus,6,5.263157895,0.174449949,"BSG, CCL2, IGFBP7, GNAS, MMP14, IGFBP2",110,367,13528,2.010601932,1,0.838168752,94.98791612
GOTERM_BP_FAT,GO:0048545~response to steroid hormone stimulus,4,3.50877193,0.201724454,"CCL2, IGFBP7, MMP14, IGFBP2",110,192,13528,2.562121212,1,0.866607582,97.03381223
GOTERM_BP_FAT,GO:0009991~response to extracellular stimulus,4,3.50877193,0.26128526,"CCL2, RPS19, IGFBP7, IGFBP2",110,220,13528,2.236033058,1,0.911322362,99.11615671
GOTERM_BP_FAT,GO:0032870~cellular response to hormone stimulus,3,2.631578947,0.29078823,"IGFBP7, GNAS, IGFBP2",110,133,13528,2.774025974,1,0.926566014,99.53227381
GOTERM_BP_FAT,GO:0007584~response to nutrient,3,2.631578947,0.311634468,"CCL2, IGFBP7, IGFBP2",110,140,13528,2.635324675,1,0.93585161,99.70645015
GOTERM_BP_FAT,GO:0009628~response to abiotic stimulus,5,4.385964912,0.344770471,"CCL2, IGFBP7, HSPB1, MMP14, IGFBP2",110,368,13528,1.670948617,1,0.944921293,99.8641254
GOTERM_BP_FAT,GO:0031667~response to nutrient levels,3,2.631578947,0.473112996,"CCL2, IGFBP7, IGFBP2",110,197,13528,1.872819566,1,0.976388824,99.99548297
GOTERM_BP_FAT,GO:0042493~response to drug,3,2.631578947,0.52191583,"CCL2, GNAS, IGFBP2",110,216,13528,1.708080808,1,0.984705981,99.99900978
,,,,,,,,,,,,
Annotation Cluster 34,Enrichment Score: 0.8098433321726589,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_BP_FAT,GO:0009408~response to heat,3,2.631578947,0.074813166,"CCL2, IGFBP7, HSPB1",110,56,13528,6.588311688,1,0.669805696,70.3037806
GOTERM_BP_FAT,GO:0009266~response to temperature stimulus,3,2.631578947,0.144198887,"CCL2, IGFBP7, HSPB1",110,83,13528,4.445125958,1,0.800869963,91.20858335
GOTERM_BP_FAT,GO:0009628~response to abiotic stimulus,5,4.385964912,0.344770471,"CCL2, IGFBP7, HSPB1, MMP14, IGFBP2",110,368,13528,1.670948617,1,0.944921293,99.8641254
,,,,,,,,,,,,
Annotation Cluster 35,Enrichment Score: 0.7866487012724063,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
SP_PIR_KEYWORDS,glycolysis,3,2.631578947,0.027116049,"ALDOA, PKM2, GAPDH",113,44,19235,11.60599356,0.998636518,0.155636459,29.87095823
GOTERM_BP_FAT,GO:0006096~glycolysis,3,2.631578947,0.054993773,"ALDOA, PKM2, GAPDH",110,47,13528,7.849903288,1,0.608562737,58.65404496
GOTERM_BP_FAT,GO:0006007~glucose catabolic process,3,2.631578947,0.079486869,"ALDOA, PKM2, GAPDH",110,58,13528,6.361128527,1,0.681609697,72.56161756
GOTERM_BP_FAT,GO:0019320~hexose catabolic process,3,2.631578947,0.106676115,"ALDOA, PKM2, GAPDH",110,69,13528,5.347035573,1,0.737129216,82.81910105
GOTERM_BP_FAT,GO:0046365~monosaccharide catabolic process,3,2.631578947,0.111858799,"ALDOA, PKM2, GAPDH",110,71,13528,5.196414853,1,0.737006099,84.31118951
GOTERM_BP_FAT,GO:0046164~alcohol catabolic process,3,2.631578947,0.138676714,"ALDOA, PKM2, GAPDH",110,81,13528,4.554882155,1,0.794666389,90.27981465
GOTERM_BP_FAT,GO:0044275~cellular carbohydrate catabolic process,3,2.631578947,0.149766884,"ALDOA, PKM2, GAPDH",110,85,13528,4.340534759,1,0.803287685,92.06045946
GOTERM_BP_FAT,GO:0016052~carbohydrate catabolic process,3,2.631578947,0.219193107,"ALDOA, PKM2, GAPDH",110,109,13528,3.384820684,1,0.883409075,97.90029024
KEGG_PATHWAY,hsa00010:Glycolysis / Gluconeogenesis,3,2.631578947,0.23014641,"ALDOA, PKM2, GAPDH",78,60,5085,3.259615385,0.999999801,0.754113568,92.66007351
GOTERM_BP_FAT,GO:0006006~glucose metabolic process,3,2.631578947,0.349982275,"ALDOA, PKM2, GAPDH",110,153,13528,2.4114082,1,0.945523928,99.88005441
GOTERM_BP_FAT,GO:0019318~hexose metabolic process,3,2.631578947,0.459787356,"ALDOA, PKM2, GAPDH",110,192,13528,1.921590909,1,0.975146448,99.9933285
GOTERM_BP_FAT,GO:0006091~generation of precursor metabolites and energy,4,3.50877193,0.463886231,"ALDOA, PKM2, GNAS, GAPDH",110,313,13528,1.571652629,1,0.975669046,99.99407655
GOTERM_BP_FAT,GO:0005996~monosaccharide metabolic process,3,2.631578947,0.536697073,"ALDOA, PKM2, GAPDH",110,222,13528,1.661916462,1,0.986495324,99.99939359
,,,,,,,,,,,,
Annotation Cluster 36,Enrichment Score: 0.7397034825901025,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_BP_FAT,GO:0007517~muscle organ development,5,4.385964912,0.090876579,"MYL6, TAGLN, TAGLN2, TPM1, ITGB1",110,211,13528,2.914261094,1,0.721349806,77.40925599
GOTERM_BP_FAT,GO:0014706~striated muscle tissue development,3,2.631578947,0.248952146,"MYL6, TPM1, ITGB1",110,119,13528,3.100381971,1,0.904839175,98.85539862
GOTERM_BP_FAT,GO:0060537~muscle tissue development,3,2.631578947,0.26688349,"MYL6, TPM1, ITGB1",110,125,13528,2.951563636,1,0.914736478,99.2151444
,,,,,,,,,,,,
Annotation Cluster 37,Enrichment Score: 0.7027518486701435,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_BP_FAT,GO:0042592~homeostatic process,14,12.28070175,0.007289176,"ALDOA, P4HB, CCL2, RPS6, CALR, TIMP1, RPS19, RPS14, MT2A, SERPINE1, TPT1, SH3BGRL3, RPS24, FTL",110,751,13528,2.292603801,0.99873423,0.218948264,10.79482972
GOTERM_BP_FAT,GO:0019725~cellular homeostasis,8,7.01754386,0.082292736,"ALDOA, P4HB, CCL2, MT2A, TPT1, SH3BGRL3, CALR, FTL",110,466,13528,2.111275849,1,0.689307063,73.838842
GOTERM_BP_FAT,"GO:0030005~cellular di-, tri-valent inorganic cation homeostasis",5,4.385964912,0.11099805,"CCL2, MT2A, TPT1, CALR, FTL",110,227,13528,2.708850621,1,0.742890927,84.07208842
GOTERM_BP_FAT,"GO:0055066~di-, tri-valent inorganic cation homeostasis",5,4.385964912,0.127286072,"CCL2, MT2A, TPT1, CALR, FTL",110,239,13528,2.572841385,1,0.77194592,88.06659057
GOTERM_BP_FAT,GO:0030003~cellular cation homeostasis,5,4.385964912,0.148966312,"CCL2, MT2A, TPT1, CALR, FTL",110,254,13528,2.420901933,1,0.804958474,91.94292449
GOTERM_BP_FAT,GO:0055080~cation homeostasis,5,4.385964912,0.199423321,"CCL2, MT2A, TPT1, CALR, FTL",110,286,13528,2.150031786,1,0.868466988,96.89745531
GOTERM_BP_FAT,GO:0048878~chemical homeostasis,7,6.140350877,0.231393562,"CCL2, MT2A, SERPINE1, TPT1, RPS6, CALR, FTL",110,512,13528,1.681392045,1,0.893875982,98.35803333
GOTERM_BP_FAT,GO:0006873~cellular ion homeostasis,5,4.385964912,0.355795949,"CCL2, MT2A, TPT1, CALR, FTL",110,374,13528,1.644141954,1,0.947599705,99.89575343
GOTERM_BP_FAT,GO:0055082~cellular chemical homeostasis,5,4.385964912,0.366824053,"CCL2, MT2A, TPT1, CALR, FTL",110,380,13528,1.618181818,1,0.952273342,99.92038947
GOTERM_BP_FAT,GO:0050801~ion homeostasis,5,4.385964912,0.419893182,"CCL2, MT2A, TPT1, CALR, FTL",110,409,13528,1.50344521,1,0.968972761,99.97970562
GOTERM_BP_FAT,GO:0006874~cellular calcium ion homeostasis,3,2.631578947,0.435326872,"CCL2, TPT1, CALR",110,183,13528,2.01609538,1,0.971843283,99.98667949
GOTERM_BP_FAT,GO:0055074~calcium ion homeostasis,3,2.631578947,0.44898964,"CCL2, TPT1, CALR",110,188,13528,1.962475822,1,0.973957103,99.99091286
GOTERM_BP_FAT,GO:0006875~cellular metal ion homeostasis,3,2.631578947,0.470463388,"CCL2, TPT1, CALR",110,196,13528,1.882374768,1,0.976831893,99.99511496
GOTERM_BP_FAT,GO:0055065~metal ion homeostasis,3,2.631578947,0.494023283,"CCL2, TPT1, CALR",110,205,13528,1.799733925,1,0.980887444,99.9975998
,,,,,,,,,,,,
Annotation Cluster 38,Enrichment Score: 0.6990233087982098,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_BP_FAT,GO:0006417~regulation of translation,4,3.50877193,0.09869502,"HSPB1, RPS4X, CALR, RPS5",110,137,13528,3.59071002,1,0.736776467,80.2593867
GOTERM_BP_FAT,GO:0010608~posttranscriptional regulation of gene expression,4,3.50877193,0.241831727,"HSPB1, RPS4X, CALR, RPS5",110,211,13528,2.331408875,1,0.901371565,98.67370222
GOTERM_BP_FAT,GO:0032268~regulation of cellular protein metabolic process,6,5.263157895,0.335059207,"HSPB1, UBB, RPS4X, CALR, RPS5, TIMP1",110,474,13528,1.556731876,1,0.941622587,99.82903579
,,,,,,,,,,,,
Annotation Cluster 39,Enrichment Score: 0.6857726285040945,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_MF_FAT,GO:0017016~Ras GTPase binding,3,2.631578947,0.167675193,"PFN1, ANXA2P2, ANXA2",106,91,12983,4.037839519,1,0.714054483,89.8026055
GOTERM_MF_FAT,GO:0031267~small GTPase binding,3,2.631578947,0.196728135,"PFN1, ANXA2P2, ANXA2",106,101,12983,3.638053428,1,0.752091393,93.44541095
GOTERM_MF_FAT,GO:0051020~GTPase binding,3,2.631578947,0.220392829,"PFN1, ANXA2P2, ANXA2",106,109,12983,3.371040332,1,0.753057098,95.48146046
GOTERM_MF_FAT,GO:0019899~enzyme binding,7,6.140350877,0.248528808,"ACTB, PFN1, VIM, SERPINE1, GNB2L1, ANXA2P2, ANXA2",106,523,12983,1.639326816,1,0.780393086,97.1396343
,,,,,,,,,,,,
Annotation Cluster 40,Enrichment Score: 0.5677109899889279,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_BP_FAT,GO:0032989~cellular component morphogenesis,8,7.01754386,0.041355898,"ACTG1, ACTB, S100A6, UCHL1, CFL1, UBB, TPM1, ITGB1",110,397,13528,2.478223036,1,0.537159811,48.28746864
GOTERM_BP_FAT,GO:0007409~axonogenesis,4,3.50877193,0.203794995,"ACTB, S100A6, UCHL1, UBB",110,193,13528,2.548845973,1,0.867065416,97.15169111
GOTERM_BP_FAT,GO:0048667~cell morphogenesis involved in neuron differentiation,4,3.50877193,0.237542549,"ACTB, S100A6, UCHL1, UBB",110,209,13528,2.353719008,1,0.89875437,98.5515756
GOTERM_BP_FAT,GO:0048812~neuron projection morphogenesis,4,3.50877193,0.246134071,"ACTB, S100A6, UCHL1, UBB",110,213,13528,2.309517712,1,0.903914762,98.78646922
GOTERM_BP_FAT,GO:0000904~cell morphogenesis involved in differentiation,4,3.50877193,0.313969952,"ACTB, S100A6, UCHL1, UBB",110,244,13528,2.01609538,1,0.936032476,99.72162149
GOTERM_BP_FAT,GO:0048858~cell projection morphogenesis,4,3.50877193,0.316178801,"ACTB, S100A6, UCHL1, UBB",110,245,13528,2.007866419,1,0.936129763,99.73529213
GOTERM_BP_FAT,GO:0000902~cell morphogenesis,5,4.385964912,0.322763486,"ACTB, S100A6, UCHL1, CFL1, UBB",110,356,13528,1.727272727,1,0.937766374,99.77241003
GOTERM_BP_FAT,GO:0031175~neuron projection development,4,3.50877193,0.340486806,"ACTB, S100A6, UCHL1, UBB",110,256,13528,1.921590909,1,0.94363641,99.84957266
GOTERM_BP_FAT,GO:0032990~cell part morphogenesis,4,3.50877193,0.340486806,"ACTB, S100A6, UCHL1, UBB",110,256,13528,1.921590909,1,0.94363641,99.84957266
GOTERM_BP_FAT,GO:0030030~cell projection organization,5,4.385964912,0.344770471,"ACTB, S100A6, UCHL1, UBB, TPM1",110,368,13528,1.670948617,1,0.944921293,99.8641254
GOTERM_BP_FAT,GO:0030182~neuron differentiation,5,4.385964912,0.471945984,"ACTB, S100A6, TUBB, UCHL1, UBB",110,438,13528,1.403902034,1,0.976650629,99.9953242
GOTERM_BP_FAT,GO:0048666~neuron development,4,3.50877193,0.51700631,"ACTB, S100A6, UCHL1, UBB",110,339,13528,1.451112899,1,0.98461364,99.99883852
,,,,,,,,,,,,
Annotation Cluster 41,Enrichment Score: 0.5321953551438519,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
SP_PIR_KEYWORDS,calcium,13,11.40350877,0.002489994,"S100A6, S100A11, SPARC, MYL12A, CALR, ANXA5, MMP14, MMP1, TPM4, MYL9, ANXA2, TPT1, CALM2",113,803,19235,2.755761029,0.450278703,0.018524518,3.166741613
GOTERM_MF_FAT,GO:0005509~calcium ion binding,16,14.03508772,0.006925268,"MYL6, S100A6, S100A11, FSTL1, SPARC, MYL12A, MMP14, CALR, ANXA5, MMP1, TPM4, ANXA2, MYL9, ANXA2P2, TPT1, CALM2",106,919,12983,2.132424498,0.734814993,0.075107803,8.281491334
SP_PIR_KEYWORDS,metal-binding,12,10.52631579,0.969071182,"S100A6, RPS29, PKM2, MT2A, RPL37A, UBB, MMP14, CALR, TPM4, MMP1, TIMP1, FTL",113,2972,19235,0.687299753,1,0.999998851,100
SP_PIR_KEYWORDS,zinc,8,7.01754386,0.976771887,"RPS29, MT2A, RPL37A, UBB, MMP14, CALR, MMP1, TIMP1",113,2189,19235,0.622096807,1,0.999999527,100
GOTERM_MF_FAT,GO:0046872~metal ion binding,22,19.29824561,0.997721784,"MYL6, S100A6, S100A11, FSTL1, SPARC, MYL12A, ANXA5, MMP14, CALR, MMP1, TPM4, ANXA2P2, ANXA2, MYL9, RPS29, PKM2, MT2A, TPT1, RPL37A, UBB, CALM2, FTL",106,4140,12983,0.650865919,1,1,100
GOTERM_MF_FAT,GO:0043169~cation binding,22,19.29824561,0.998136157,"MYL6, S100A6, S100A11, FSTL1, SPARC, MYL12A, ANXA5, MMP14, CALR, MMP1, TPM4, ANXA2P2, ANXA2, MYL9, RPS29, PKM2, MT2A, TPT1, RPL37A, UBB, CALM2, FTL",106,4179,12983,0.644791794,1,1,100
GOTERM_MF_FAT,GO:0043167~ion binding,22,19.29824561,0.998654143,"MYL6, S100A6, S100A11, FSTL1, SPARC, MYL12A, ANXA5, MMP14, CALR, MMP1, TPM4, ANXA2P2, ANXA2, MYL9, RPS29, PKM2, MT2A, TPT1, RPL37A, UBB, CALM2, FTL",106,4241,12983,0.635365458,1,1,100
GOTERM_MF_FAT,GO:0008270~zinc ion binding,8,7.01754386,0.999752176,"S100A6, RPS29, MT2A, RPL37A, UBB, MMP14, CALR, MMP1",106,2311,12983,0.423993534,1,1,100
GOTERM_MF_FAT,GO:0046914~transition metal ion binding,10,8.771929825,0.999887963,"S100A6, RPS29, MT2A, RPL37A, UBB, SPARC, MMP14, CALR, MMP1, FTL",106,2785,12983,0.439788625,1,1,100
,,,,,,,,,,,,
Annotation Cluster 42,Enrichment Score: 0.359002737636536,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_MF_FAT,GO:0003729~mRNA binding,5,4.385964912,0.001981678,"RPS14, RPL35, RPS13, CALR, RPS5",106,66,12983,9.278873642,0.315369507,0.037178845,2.437343096
GOTERM_BP_FAT,GO:0010605~negative regulation of macromolecule metabolic process,6,5.263157895,0.711691831,"RPS14, S100A11, RPS13, UBB, CALR, TIMP1",110,734,13528,1.005300966,1,0.998524615,99.99999963
GOTERM_BP_FAT,"GO:0045934~negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process",4,3.50877193,0.786480168,"RPS14, S100A11, RPS13, CALR",110,512,13528,0.960795455,1,0.999581922,100
GOTERM_BP_FAT,GO:0051253~negative regulation of RNA metabolic process,3,2.631578947,0.793367285,"RPS14, RPS13, CALR",110,362,13528,1.019186339,1,0.999629771,100
GOTERM_BP_FAT,GO:0051172~negative regulation of nitrogen compound metabolic process,4,3.50877193,0.794177017,"RPS14, S100A11, RPS13, CALR",110,519,13528,0.947836749,1,0.999620926,100
GOTERM_BP_FAT,GO:0010558~negative regulation of macromolecule biosynthetic process,3,2.631578947,0.93851707,"RPS14, S100A11, CALR",110,547,13528,0.674488948,1,0.999997688,100
GOTERM_BP_FAT,GO:0031327~negative regulation of cellular biosynthetic process,3,2.631578947,0.944166316,"RPS14, S100A11, CALR",110,561,13528,0.657656782,1,0.999998419,100
GOTERM_BP_FAT,GO:0009890~negative regulation of biosynthetic process,3,2.631578947,0.948615834,"RPS14, S100A11, CALR",110,573,13528,0.643883865,1,0.999998765,100
GOTERM_BP_FAT,GO:0051252~regulation of RNA metabolic process,4,3.50877193,0.999976702,"PFN1, RPS14, RPS13, CALR",110,1813,13528,0.2713333,1,1,100
,,,,,,,,,,,,
Annotation Cluster 43,Enrichment Score: 0.31683411612400986,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_CC_FAT,GO:0009986~cell surface,6,5.263157895,0.167123724,"P4HB, BGN, TNFRSF12A, HSPB1, CALR, ITGB1",108,348,12782,2.04054917,1,0.487285412,89.46434079
GOTERM_CC_FAT,GO:0000267~cell fraction,11,9.649122807,0.421576846,"ACTG1, ACTB, P4HB, SERPINE1, HSPB1, GNAS, PTMS, CALR, CD151, ITGB1, ANXA2",108,1083,12782,1.202096372,1,0.831648216,99.8813713
GOTERM_CC_FAT,GO:0005626~insoluble fraction,6,5.263157895,0.839434013,"P4HB, HSPB1, GNAS, CALR, CD151, ITGB1",108,839,12782,0.846377963,1,0.994910854,99.99999998
GOTERM_CC_FAT,GO:0005624~membrane fraction,5,4.385964912,0.913612681,"P4HB, GNAS, CALR, CD151, ITGB1",108,809,12782,0.731470036,1,0.998821996,100
,,,,,,,,,,,,
Annotation Cluster 44,Enrichment Score: 0.15335681739380738,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_BP_FAT,GO:0043065~positive regulation of apoptosis,4,3.50877193,0.678111081,"TUBB, RPL11, UBB, RPS6",110,430,13528,1.144016913,1,0.997950989,99.99999794
GOTERM_BP_FAT,GO:0043068~positive regulation of programmed cell death,4,3.50877193,0.682691755,"TUBB, RPL11, UBB, RPS6",110,433,13528,1.136090699,1,0.998033219,99.99999836
GOTERM_BP_FAT,GO:0010942~positive regulation of cell death,4,3.50877193,0.685718971,"TUBB, RPL11, UBB, RPS6",110,435,13528,1.130867294,1,0.998062228,99.99999858
GOTERM_BP_FAT,GO:0006917~induction of apoptosis,3,2.631578947,0.733336428,"TUBB, RPL11, UBB",110,320,13528,1.152954545,1,0.998897817,99.99999989
GOTERM_BP_FAT,GO:0012502~induction of programmed cell death,3,2.631578947,0.734921564,"TUBB, RPL11, UBB",110,321,13528,1.149362787,1,0.998889282,99.9999999
,,,,,,,,,,,,
Annotation Cluster 45,Enrichment Score: 0.14873830458354112,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_BP_FAT,GO:0046907~intracellular transport,8,7.01754386,0.278649483,"MYL6, RPL23, UCHL1, GNAS, RPL11, CALR, TPM1, FTL",110,657,13528,1.497495503,1,0.919898699,99.39035855
GOTERM_BP_FAT,GO:0006605~protein targeting,3,2.631578947,0.519422264,"RPL23, RPL11, CALR",110,215,13528,1.71602537,1,0.984651965,99.99892599
GOTERM_BP_FAT,GO:0006886~intracellular protein transport,3,2.631578947,0.808202774,"RPL23, RPL11, CALR",110,374,13528,0.986485173,1,0.999708522,100
GOTERM_BP_FAT,GO:0008104~protein localization,6,5.263157895,0.846608844,"RPL23, TMSB4X, GNAS, RPL11, TMSB10, CALR",110,882,13528,0.836611008,1,0.99988773,100
GOTERM_BP_FAT,GO:0034613~cellular protein localization,3,2.631578947,0.848193063,"RPL23, RPL11, CALR",110,411,13528,0.897677505,1,0.999887951,100
GOTERM_BP_FAT,GO:0070727~cellular macromolecule localization,3,2.631578947,0.851082307,"RPL23, RPL11, CALR",110,414,13528,0.891172596,1,0.999892813,100
GOTERM_BP_FAT,GO:0015031~protein transport,4,3.50877193,0.949358354,"RPL23, GNAS, RPL11, CALR",110,762,13528,0.645573849,1,0.999998762,100
GOTERM_BP_FAT,GO:0045184~establishment of protein localization,4,3.50877193,0.951513971,"RPL23, GNAS, RPL11, CALR",110,769,13528,0.639697364,1,0.999998913,100
,,,,,,,,,,,,
Annotation Cluster 46,Enrichment Score: 0.1274661148667562,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_BP_FAT,GO:0008219~cell death,6,5.263157895,0.694356826,"IER3, TNFRSF12A, LGALS1, PKM2, HSPB1, UBB",110,719,13528,1.026273865,1,0.998203288,99.99999908
GOTERM_BP_FAT,GO:0016265~death,6,5.263157895,0.700211283,"IER3, TNFRSF12A, LGALS1, PKM2, HSPB1, UBB",110,724,13528,1.019186339,1,0.998254421,99.99999932
GOTERM_BP_FAT,GO:0012501~programmed cell death,5,4.385964912,0.731544088,"IER3, TNFRSF12A, LGALS1, PKM2, UBB",110,611,13528,1.006397857,1,0.998902199,99.99999988
GOTERM_BP_FAT,GO:0006915~apoptosis,4,3.50877193,0.86912696,"IER3, TNFRSF12A, LGALS1, UBB",110,602,13528,0.817154938,1,0.999936168,100
,,,,,,,,,,,,
Annotation Cluster 47,Enrichment Score: 0.11256240207312497,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_CC_FAT,GO:0000139~Golgi membrane,3,2.631578947,0.463172486,"BSG, GNAS, B2M",108,186,12782,1.908900836,1,0.858229336,99.95264777
GOTERM_CC_FAT,GO:0044431~Golgi apparatus part,3,2.631578947,0.709474649,"BSG, GNAS, B2M",108,294,12782,1.207671958,1,0.974967799,99.99997523
GOTERM_CC_FAT,GO:0012505~endomembrane system,5,4.385964912,0.899631549,"S100A6, BSG, GNAS, TAGLN2, B2M",108,782,12782,0.756725395,1,0.998543641,100
GOTERM_CC_FAT,GO:0005794~Golgi apparatus,5,4.385964912,0.939771761,"BSG, ARPC2, PSAP, GNAS, B2M",108,872,12782,0.678623004,1,0.999450379,100
GOTERM_CC_FAT,GO:0031090~organelle membrane,5,4.385964912,0.984966108,"BSG, GNAS, CD63, TAGLN2, B2M",108,1096,12782,0.539926331,1,0.999981338,100
,,,,,,,,,,,,
Annotation Cluster 48,Enrichment Score: 0.1020497866510477,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_BP_FAT,GO:0032268~regulation of cellular protein metabolic process,6,5.263157895,0.335059207,"HSPB1, UBB, RPS4X, CALR, RPS5, TIMP1",110,474,13528,1.556731876,1,0.941622587,99.82903579
GOTERM_BP_FAT,GO:0010557~positive regulation of macromolecule biosynthetic process,3,2.631578947,0.970949657,"UBB, RPS4X, CALR",110,654,13528,0.564136781,1,0.999999885,100
GOTERM_BP_FAT,GO:0031328~positive regulation of cellular biosynthetic process,3,2.631578947,0.976742495,"UBB, RPS4X, CALR",110,685,13528,0.538606503,1,0.999999954,100
GOTERM_BP_FAT,GO:0009891~positive regulation of biosynthetic process,3,2.631578947,0.978362426,"UBB, RPS4X, CALR",110,695,13528,0.530856769,1,0.999999964,100
GOTERM_BP_FAT,GO:0010604~positive regulation of macromolecule metabolic process,3,2.631578947,0.993465865,"UBB, RPS4X, CALR",110,857,13528,0.430508115,1,1,100
,,,,,,,,,,,,
Annotation Cluster 49,Enrichment Score: 0.09744984945218829,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_BP_FAT,GO:0007049~cell cycle,6,5.263157895,0.756571674,"S100A6, TUBB, UBB, CALR, ITGB1, CALM2",110,776,13528,0.950890347,1,0.999222058,99.99999997
GOTERM_BP_FAT,GO:0000278~mitotic cell cycle,3,2.631578947,0.803364975,"TUBB, UBB, ITGB1",110,370,13528,0.997149877,1,0.999684489,100
GOTERM_BP_FAT,GO:0022402~cell cycle process,4,3.50877193,0.839242524,"TUBB, UBB, CALR, ITGB1",110,565,13528,0.870667739,1,0.999865571,100
,,,,,,,,,,,,
Annotation Cluster 50,Enrichment Score: 0.08315629093288333,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_MF_FAT,GO:0004175~endopeptidase activity,4,3.50877193,0.588393848,"UCHL1, SERPINE1, MMP14, MMP1",106,375,12983,1.306465409,1,0.984002592,99.99839905
SP_PIR_KEYWORDS,Protease,3,2.631578947,0.776773327,"UCHL1, MMP14, MMP1",113,484,19235,1.055090324,1,0.997980907,99.99999961
GOTERM_MF_FAT,"GO:0070011~peptidase activity, acting on L-amino acid peptides",4,3.50877193,0.826784688,"UCHL1, SERPINE1, MMP14, MMP1",106,549,12983,0.892394405,1,0.999413562,99.99999997
GOTERM_MF_FAT,GO:0008233~peptidase activity,4,3.50877193,0.849039104,"UCHL1, SERPINE1, MMP14, MMP1",106,574,12983,0.853527053,1,0.999610504,99.99999999
GOTERM_BP_FAT,GO:0006508~proteolysis,4,3.50877193,0.992613462,"UCHL1, UBB, MMP14, MMP1",110,1054,13528,0.466724168,1,1,100
SP_PIR_KEYWORDS,hydrolase,4,3.50877193,0.995404381,"UCHL1, MMP14, GAPDH, MMP1",113,1555,19235,0.437868139,1,0.999999998,100
,,,,,,,,,,,,
Annotation Cluster 51,Enrichment Score: 0.0018810754285662863,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_BP_FAT,GO:0006357~regulation of transcription from RNA polymerase II promoter,3,2.631578947,0.982850422,"PFN1, RPS14, CALR",110,727,13528,0.507490309,1,0.999999986,100
GOTERM_BP_FAT,GO:0051252~regulation of RNA metabolic process,4,3.50877193,0.999976702,"PFN1, RPS14, RPS13, CALR",110,1813,13528,0.2713333,1,1,100
GOTERM_BP_FAT,"GO:0006355~regulation of transcription, DNA-dependent",3,2.631578947,0.999996315,"PFN1, RPS14, CALR",110,1773,13528,0.208091063,1,1,100
GOTERM_BP_FAT,GO:0045449~regulation of transcription,4,3.50877193,0.999999974,"PFN1, RPS14, UBB, CALR",110,2601,13528,0.189130055,1,1,100
,,,,,,,,,,,,
Annotation Cluster 52,Enrichment Score: 4.999151074841068E-4,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_CC_FAT,GO:0044459~plasma membrane part,11,9.649122807,0.992995347,"TUBB, ARPC2, GNAS, MMP14, CD63, CALR, IGFBP2, CD151, TPM1, ITGB1, B2M",108,2203,12782,0.590953414,1,0.999996302,100
GOTERM_CC_FAT,GO:0005887~integral to plasma membrane,4,3.50877193,0.99796626,"MMP14, CD63, CD151, ITGB1",108,1188,12782,0.398491084,1,0.999999797,100
GOTERM_CC_FAT,GO:0031226~intrinsic to plasma membrane,4,3.50877193,0.998343821,"MMP14, CD63, CD151, ITGB1",108,1215,12782,0.389635726,1,0.999999848,100
UP_SEQ_FEATURE,topological domain:Extracellular,7,6.140350877,0.99923829,"IER3, BSG, TNFRSF12A, MMP14, CD63, CD151, ITGB1",113,2719,19113,0.435450956,1,1,100
UP_SEQ_FEATURE,topological domain:Cytoplasmic,7,6.140350877,0.999973786,"IER3, BSG, TNFRSF12A, MMP14, CD63, CD151, ITGB1",113,3374,19113,0.350916168,1,1,100
SP_PIR_KEYWORDS,membrane,14,12.28070175,0.999999938,"IER3, P4HB, S100A6, BSG, TNFRSF12A, CD63, MMP14, CD151, ITGB1, OST4, COL6A2, GNAS, GNB2L1, GAPDH",113,6256,19235,0.380929883,1,1,100
UP_SEQ_FEATURE,transmembrane region,8,7.01754386,0.999999984,"IER3, BSG, TNFRSF12A, OST4, MMP14, CD63, CD151, ITGB1",113,4911,19113,0.275531,1,1,100
SP_PIR_KEYWORDS,transmembrane,8,7.01754386,0.999999987,"IER3, BSG, TNFRSF12A, OST4, MMP14, CD63, CD151, ITGB1",113,4973,19235,0.273832679,1,1,100
GOTERM_CC_FAT,GO:0016021~integral to membrane,9,7.894736842,1,"IER3, BSG, TNFRSF12A, PSAP, OST4, MMP14, CD63, CD151, ITGB1",108,5297,12782,0.201088667,1,1,100
GOTERM_CC_FAT,GO:0031224~intrinsic to membrane,10,8.771929825,1,"IER3, BSG, TNFRSF12A, PSAP, OST4, GNAS, MMP14, CD63, CD151, ITGB1",108,5485,12782,0.215773659,1,1,100
,,,,,,,,,,,,
Annotation Cluster 53,Enrichment Score: 2.3099279028253913E-4,,,,,,,,,,,
Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
SP_PIR_KEYWORDS,atp-binding,3,2.631578947,0.9969396,"ACTG1, ACTB, PKM2",113,1326,19235,0.385115925,1,0.999999999,100
GOTERM_MF_FAT,GO:0005524~ATP binding,3,2.631578947,0.999956997,"ACTG1, ACTB, PKM2",106,1477,12983,0.248776842,1,1,100
GOTERM_MF_FAT,GO:0032559~adenyl ribonucleotide binding,3,2.631578947,0.999963696,"ACTG1, ACTB, PKM2",106,1497,12983,0.24545317,1,1,100
GOTERM_MF_FAT,GO:0030554~adenyl nucleotide binding,3,2.631578947,0.999981645,"ACTG1, ACTB, PKM2",106,1577,12983,0.233001519,1,1,100
GOTERM_MF_FAT,GO:0001883~purine nucleoside binding,3,2.631578947,0.999985062,"ACTG1, ACTB, PKM2",106,1601,12983,0.22950868,1,1,100
GOTERM_MF_FAT,GO:0001882~nucleoside binding,3,2.631578947,0.999986412,"ACTG1, ACTB, PKM2",106,1612,12983,0.227942553,1,1,100