Identification of enzymes to fill pathway holes in CRIB

Nodes used in Bayesian network: SAME-GENE DIRECTON ADJACENT SSCORE EVALS ALN RANK

Summary Statistics:

Number of pathways analyzed: 96

Number of pathway holes: 209

One or more candidates have been identified for 61 holes.

List of Pathways

xyloglucan degradation II (exoglucanase)

Total # of reactions in pathway = 6

Present reactions: 3

Reaction Protein(s)
RXN-12398 (# # #)
RXN-12399 (# # #)
RXN-12400 (# # #)

Missing reactions: 3

3.2.1.120-RXN
RXN-12397
RXN-12402

Evidence for , EC# EC-3.2.1.1203.2.1.120-RXN

no BLAST hits found

Evidence for , EC# EC-3.2.1.155RXN-12397

no BLAST hits found

Evidence for isoprimeverose α-xylosidase, EC# EC-3.2.1.177RXN-12402

no BLAST hits found

xanthine and xanthosine salvage

Total # of reactions in pathway = 2

Present reactions: 1

Reaction Protein(s)
XANTHOSINEPHOSPHORY-RXN (#)

Missing reactions: 1

XANPRIBOSYLTRAN-RXN

Evidence for , EC# EC-2.4.2.22XANPRIBOSYLTRAN-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

valine degradation II

Total # of reactions in pathway = 3

Present reactions: 1

Reaction Protein(s)
RXN-7657 (#)

Missing reactions: 2

BRANCHED-CHAINAMINOTRANSFERVAL-RXN
RXN-7643

Evidence for Valine transaminase, EC# EC-2.6.1.42BRANCHED-CHAINAMINOTRANSFERVAL-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-4.1.1.72RXN-7643

no BLAST hits found

urate biosynthesis/inosine 5'-phosphate degradation

Total # of reactions in pathway = 4

Present reactions: 3

Reaction Protein(s)
IMP-DEHYDROG-RXN (#)
XMPXAN-RXN (#)
XANTHOSINEPHOSPHORY-RXN (#)

Missing reactions: 1

RXN0-901

Evidence for , EC# EC-1.17.1.4RXN0-901

no BLAST hits found

UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)

Total # of reactions in pathway = 8

Present reactions: 7

Reaction Protein(s)
UDPNACETYLGLUCOSAMENOLPYRTRANS-RXN (#)
UDPNACETYLMURAMATEDEHYDROG-RXN (#)
UDP-NACMUR-ALA-LIG-RXN (#)
UDP-NACMURALA-GLU-LIG-RXN (#)
GLUTRACE-RXN (#)
DALADALALIG-RXN (#)
6.3.2.10-RXN (#)

Missing reactions: 1

6.3.2.7-RXN

Evidence for , EC# EC-6.3.2.76.3.2.7-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

tyrosine degradation III

Total # of reactions in pathway = 4

Present reactions: 1

Reaction Protein(s)
RXN3O-4113 (#)

Missing reactions: 3

TYRAMINOTRANS-RXN
4.1.1.80-RXN
RXN3O-4157

Evidence for Tyrosine transaminase, EC# EC-2.6.1.57TYRAMINOTRANS-RXN

no BLAST hits found

Evidence for , EC# EC-4.1.1.804.1.1.80-RXN

no BLAST hits found

Evidence for , EC# EC-2.6.1.58RXN3O-4157

no BLAST hits found

tryptophan degradation IV (via indole-3-lactate)

Total # of reactions in pathway = 2

Present reactions: 1

Reaction Protein(s)
TRYPTOPHAN-AMINOTRANSFERASE-RXN (#)

Missing reactions: 1

INDOLELACTATE-DEHYDROGENASE-RXN

Evidence for , EC# EC-1.1.1.110INDOLELACTATE-DEHYDROGENASE-RXN

no BLAST hits found

tRNA processing pathway I

Total # of reactions in pathway = 10

Present reactions: 6

Reaction Protein(s)
RXN0-6478 (# #)
RXN0-6479 (# # #)
RXN0-4222 (#)
RXN0-6480 (# # #)
3.1.26.5-RXN (# # #)
RXN0-6485 (# #)

Missing reactions: 4

RXN0-6482
RXN0-6484
RXN0-6483
RXN0-6481

Evidence for , EC# EC-2.7.7.56RXN0-6482

no BLAST hits found

Evidence for , EC# EC-3.1.13.5RXN0-6484

no BLAST hits found

Evidence for , EC# EC-3.1.13.5RXN0-6483

no BLAST hits found

Evidence for , EC# EC-2.7.7.56RXN0-6481

no BLAST hits found

threonine degradation I

Total # of reactions in pathway = 4

Present reactions: 2

Reaction Protein(s)
THREDEHYD-RXN (# #)
PTAALT-RXN (#)

Missing reactions: 2

KETOBUTFORMLY-RXN
PROPKIN-RXN

Evidence for 2-ketobutyrate formate-lyase, EC# EC-2.3.1KETOBUTFORMLY-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-2.7.2.15PROPKIN-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

threonine biosynthesis from homoserine

Total # of reactions in pathway = 2

Present reactions: 1

Reaction Protein(s)
HOMOSERKIN-RXN (#)

Missing reactions: 1

THRESYN-RXN

Evidence for , EC# EC-4.2.3.1THRESYN-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

thiazole biosynthesis II (Bacillus)

Total # of reactions in pathway = 7

Present reactions: 5

Reaction Protein(s)
THIAZOLSYN2-RXN NIL
DXS-RXN (#)
RXN-9789 NIL
RXN-12621 NIL
RXN0-308 (# # # # #)

Missing reactions: 2

RXN-12609
RXN-12614

Evidence for , EC# EC-5.3.99.10RXN-12609

no BLAST hits found

Evidence for glycine oxidaseRXN-12614

no BLAST hits found

thiazole biosynthesis I (E. coli)

Total # of reactions in pathway = 6

Present reactions: 5

Reaction Protein(s)
THIAZOLSYN2-RXN NIL
DXS-RXN (#)
RXN-9787 (# # # # #)
RXN-9788 NIL
RXN-9789 NIL

Missing reactions: 1

RXN-11319

Evidence for , EC# EC-4.1.99.19RXN-11319

no BLAST hits found

thiamin diphosphate biosynthesis IV (eukaryotes)

Total # of reactions in pathway = 3

Present reactions: 2

Reaction Protein(s)
RXNQT-4191 (#)
THIAMIN-PYROPHOSPHOKINASE-RXN (# #)

Missing reactions: 1

THI-P-SYN-RXN

Evidence for , EC# EC-2.5.1.3THI-P-SYN-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

thiamin diphosphate biosynthesis III (Staphylococcus)

Total # of reactions in pathway = 3

Present reactions: 2

Reaction Protein(s)
RXNQT-4191 (#)
THIAMIN-PYROPHOSPHOKINASE-RXN (# #)

Missing reactions: 1

RXN-12610

Evidence for thiamine-phosphate diphosphorylase, EC# EC-2.5.1.3RXN-12610

no BLAST hits found

tetrahydrofolate biosynthesis

Total # of reactions in pathway = 3

Present reactions: 1

Reaction Protein(s)
H2PTEROATESYNTH-RXN (#)

Missing reactions: 2

DIHYDROFOLATESYNTH-RXN
DIHYDROFOLATEREDUCT-RXN

Evidence for , EC# EC-6.3.2.12DIHYDROFOLATESYNTH-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-1.5.1.3DIHYDROFOLATEREDUCT-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

superpathway of heme biosynthesis from uroporphyrinogen-III

Total # of reactions in pathway = 5

Present reactions: 4

Reaction Protein(s)
PROTOPORGENOXI-RXN (#)
PROTOHEMEFERROCHELAT-RXN (#)
RXN0-1461 (#)
HEMESYN2-PWY NIL

Missing reactions: 1

UROGENDECARBOX-RXN

Evidence for , EC# EC-4.1.1.37UROGENDECARBOX-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

superpathway of 5-aminoimidazole ribonucleotide biosynthesis

Total # of reactions in pathway = 6

Present reactions: 5

Reaction Protein(s)
PRPPAMIDOTRANS-RXN (#)
GLYRIBONUCSYN-RXN (#)
FGAMSYN-RXN (#)
AIRS-RXN (#)
PWY-6121 NIL

Missing reactions: 1

GARTRANSFORMYL2-RXN

Evidence for , EC# EC-2.1.2GARTRANSFORMYL2-RXN

no BLAST hits found

superoxide radicals degradation

Total # of reactions in pathway = 2

Present reactions: 1

Reaction Protein(s)
SUPEROX-DISMUT-RXN (# #)

Missing reactions: 1

CATAL-RXN

Evidence for , EC# EC-1.11.1.6CATAL-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

sucrose degradation IV

Total # of reactions in pathway = 4

Present reactions: 1

Reaction Protein(s)
SUCROSE-PHOSPHORYLASE-RXN (#)

Missing reactions: 3

FRUCTOKINASE-RXN
PHOSPHOGLUCMUT-RXN
PGLUCISOM-RXN

Evidence for fructokinase, EC# EC-2.7.1.4FRUCTOKINASE-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-5.4.2.2PHOSPHOGLUCMUT-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for glucose-6-phosphate isomerase, EC# EC-5.3.1.9PGLUCISOM-RXN

no BLAST hits found

sucrose degradation I

Total # of reactions in pathway = 2

Present reactions: 1

Reaction Protein(s)
3.2.1.26-RXN (# #)

Missing reactions: 1

FRUCTOKINASE-RXN

Evidence for fructokinase, EC# EC-2.7.1.4FRUCTOKINASE-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

sucrose biosynthesis

Total # of reactions in pathway = 9

Present reactions: 5

Reaction Protein(s)
GLUC1PURIDYLTRANS-RXN (# #)
PHOSGLYPHOS-RXN (#)
GAPOXNPHOSPHN-RXN (#)
F16ALDOLASE-RXN (#)
F16BDEPHOS-RXN (# #)

Missing reactions: 4

PHOSPHOGLUCMUT-RXN
SUCROSE-PHOSPHATE-SYNTHASE-RXN
SUCROSE-PHOSPHATASE-RXN
PGLUCISOM-RXN

Evidence for , EC# EC-5.4.2.2PHOSPHOGLUCMUT-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-2.4.1.14SUCROSE-PHOSPHATE-SYNTHASE-RXN

no BLAST hits found

Evidence for , EC# EC-3.1.3.24SUCROSE-PHOSPHATASE-RXN

no BLAST hits found

Evidence for glucose-6-phosphate isomerase, EC# EC-5.3.1.9PGLUCISOM-RXN

no BLAST hits found

starch degradation III

Total # of reactions in pathway = 4

Present reactions: 2

Reaction Protein(s)
CYCLOMALTODEXTRINASE-RXN (#)
RXN-12171 (# #)

Missing reactions: 2

PHOSPHOGLUCMUT-RXN
RXN-12181

Evidence for , EC# EC-5.4.2.2PHOSPHOGLUCMUT-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for cyclodextrin glucanotransferase, EC# EC-2.4.1.19RXN-12181

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

starch biosynthesis

Total # of reactions in pathway = 5

Present reactions: 3

Reaction Protein(s)
GLUC1PADENYLTRANS-RXN (#)
GLYCOGENSYN-RXN (#)
RXN-7710 (#)

Missing reactions: 2

PGLUCISOM-RXN
PHOSPHOGLUCMUT-RXN

Evidence for glucose-6-phosphate isomerase, EC# EC-5.3.1.9PGLUCISOM-RXN

no BLAST hits found

Evidence for , EC# EC-5.4.2.2PHOSPHOGLUCMUT-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

stachyose degradation

Total # of reactions in pathway = 8

Present reactions: 5

Reaction Protein(s)
UDPGLUCEPIM-RXN (# #)
RXN-11501 (# # #)
GALACTURIDYLYLTRANS-RXN (# #)
GLUC1PURIDYLTRANS-RXN (# #)
GALACTOKIN-RXN (#)

Missing reactions: 3

UTPHEXPURIDYLYLTRANS-RXN
RXN-11502
RXN-11505

Evidence for , EC# EC-2.7.7.10UTPHEXPURIDYLYLTRANS-RXN

no BLAST hits found

Evidence for , EC# EC-3.2.1RXN-11502

no BLAST hits found

Evidence for RXN-11505

no BLAST hits found

serine biosynthesis

Total # of reactions in pathway = 3

Present reactions: 2

Reaction Protein(s)
PGLYCDEHYDROG-RXN (#)
RXN0-5114 (#)

Missing reactions: 1

PSERTRANSAM-RXN

Evidence for , EC# EC-2.6.1.52PSERTRANSAM-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

seleno-amino acid biosynthesis

Total # of reactions in pathway = 5

Present reactions: 3

Reaction Protein(s)
RXN-12726 (#)
RXN-12729 (#)
SERINE-O-ACETTRAN-RXN (#)

Missing reactions: 2

RXN-12728
RXN-12730

Evidence for , EC# EC-2.5.1RXN-12728

no BLAST hits found

Evidence for , EC# EC-2.1.1.14RXN-12730

salvage pathways of pyrimidine deoxyribonucleotides

Total # of reactions in pathway = 5

Present reactions: 3

Reaction Protein(s)
DURIDKI-RXN (#)
THYM-PHOSPH-RXN (#)
THYKI-RXN (#)

Missing reactions: 2

CYTIDEAM-RXN
URA-PHOSPH-RXN

Evidence for , EC# EC-3.5.4.14CYTIDEAM-RXN

no BLAST hits found

Evidence for URA-PHOSPH-RXN

no BLAST hits found

respiration (anaerobic)

Total # of reactions in pathway = 13

Present reactions: 4

Reaction Protein(s)
PEPDEPHOS-RXN (#)
PYRUVDEH-RXN (#)
PYRUVFORMLY-RXN (#)
2PGADEHYDRAT-RXN (#)

Missing reactions: 9

CITSYN-RXN
ACONITATEDEHYDR-RXN
ACONITATEHYDR-RXN
PEPCARBOX-RXN
FUMHYDR-RXN
FHLMULTI-RXN
R601-RXN
ISOCITDEH-RXN
MALATE-DEH-RXN

Evidence for , EC# EC-2.3.3.1CITSYN-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-4.2.1.3ACONITATEDEHYDR-RXN

no BLAST hits found

Evidence for , EC# EC-4.2.1.3ACONITATEHYDR-RXN

no BLAST hits found

Evidence for , EC# EC-4.1.1.31PEPCARBOX-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-4.2.1.2FUMHYDR-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for FHLMULTI-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-1.3.5.4R601-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-1.1.1.42ISOCITDEH-RXN

no BLAST hits found

Evidence for , EC# EC-1.1.1.37MALATE-DEH-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

queuosine biosynthesis

Total # of reactions in pathway = 4

Present reactions: 1

Reaction Protein(s)
RXN0-1342 (#)

Missing reactions: 3

RXN0-4022
RXN0-1321
RXN-12104

Evidence for , EC# EC-1.7.1.13RXN0-4022

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-2.4.2.29RXN0-1321

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for RXN-12104

no BLAST hits found

pyruvate fermentation to butanoate

Total # of reactions in pathway = 7

Present reactions: 4

Reaction Protein(s)
PHOSPHATE-BUTYRYLTRANSFERASE-RXN (#)
BUTYRATE-KINASE-RXN (#)
PYRUFLAVREDUCT-RXN NIL
BUTYRYL-COA-DEHYDROGENASE-RXN NIL

Missing reactions: 3

ACETYL-COA-ACETYLTRANSFER-RXN
RXN-11662
RXN-11667

Evidence for , EC# EC-2.3.1.9ACETYL-COA-ACETYLTRANSFER-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-1.1.1.35RXN-11662

no BLAST hits found

Evidence for (S)-3-hydroxybutanoyl-CoA dehydrogenase, EC# EC-4.2.1RXN-11667

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

pyrimidine ribonucleotides interconversion

Total # of reactions in pathway = 11

Present reactions: 4

Reaction Protein(s)
2.7.4.22-RXN (#)
RXN-12196 (# # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # #)
RXN-12195 (# # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # # #)
CMPKI-RXN (#)

Missing reactions: 7

UDPKIN-RXN
CTPSYN-RXN
CDPKIN-RXN
RXN-12200
RXN-12199
RXN-12198
RXN-12197

Evidence for , EC# EC-2.7.4.6UDPKIN-RXN

no BLAST hits found

Evidence for , EC# EC-6.3.4.2CTPSYN-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-2.7.4.6CDPKIN-RXN

no BLAST hits found

Evidence for , EC# EC-3.6.1.5RXN-12200

no BLAST hits found

Evidence for , EC# EC-3.6.1.5RXN-12199

no BLAST hits found

Evidence for , EC# EC-3.6.1.6RXN-12198

Evidence for , EC# EC-3.6.1.6RXN-12197

pyrimidine ribonucleosides degradation II

Total # of reactions in pathway = 2

Present reactions: 1

Reaction Protein(s)
CYTIDEAM2-RXN (# #)

Missing reactions: 1

URIDINE-NUCLEOSIDASE-RXN

Evidence for , EC# EC-3.2.2.3URIDINE-NUCLEOSIDASE-RXN

no BLAST hits found

pyrimidine ribonucleosides degradation I

Total # of reactions in pathway = 3

Present reactions: 2

Reaction Protein(s)
CYTIDEAM2-RXN (# #)
PPENTOMUT-RXN (#)

Missing reactions: 1

URPHOS-RXN

Evidence for , EC# EC-2.4.2.3URPHOS-RXN

no BLAST hits found

pyrimidine deoxyribonucleotides de novo biosynthesis II

Total # of reactions in pathway = 14

Present reactions: 9

Reaction Protein(s)
RXN-8850 (#)
DTMPKI-RXN (#)
DUTP-PYROP-RXN (#)
UDPREDUCT-RXN NIL
CDPREDUCT-RXN NIL
RXN0-723 NIL
RXN0-724 NIL
RIBONUCLEOSIDE-DIP-REDUCTII-RXN NIL
RXN0-722 NIL

Missing reactions: 5

DTDPKIN-RXN
DUDPKIN-RXN
DCTP-DEAM-RXN
DCDPKIN-RXN
RXN-11556

Evidence for , EC# EC-2.7.4.6DTDPKIN-RXN

no BLAST hits found

Evidence for , EC# EC-2.7.4.6DUDPKIN-RXN

no BLAST hits found

Evidence for , EC# EC-3.5.4.13DCTP-DEAM-RXN

no BLAST hits found

Evidence for , EC# EC-2.7.4.6DCDPKIN-RXN

no BLAST hits found

Evidence for CDP reductase, EC# EC-1.17.4RXN-11556

no BLAST hits found

pyrimidine deoxyribonucleosides degradation

Total # of reactions in pathway = 6

Present reactions: 4

Reaction Protein(s)
THYM-PHOSPH-RXN (#)
D-PPENTOMUT-RXN (#)
DEOXYRIBOSE-P-ALD-RXN (# #)
ACETALD-DEHYDROG-RXN (# #)

Missing reactions: 2

CYTIDEAM-RXN
URA-PHOSPH-RXN

Evidence for , EC# EC-3.5.4.14CYTIDEAM-RXN

no BLAST hits found

Evidence for URA-PHOSPH-RXN

no BLAST hits found

purine ribonucleosides degradation to ribose-1-phosphate

Total # of reactions in pathway = 6

Present reactions: 2

Reaction Protein(s)
XANTHOSINEPHOSPHORY-RXN (#)
PPENTOMUT-RXN (#)

Missing reactions: 4

ADENPHOSPHOR-RXN
ADENODEAMIN-RXN
INOPHOSPHOR-RXN
RXN0-5199

Evidence for adenosine phosphorylase, EC# EC-2.4.2.1ADENPHOSPHOR-RXN

no BLAST hits found

Evidence for , EC# EC-3.5.4.4ADENODEAMIN-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for inosine phosphorylase, EC# EC-2.4.2.1INOPHOSPHOR-RXN

no BLAST hits found

Evidence for guanosine phosphorylase, EC# EC-2.4.2.1RXN0-5199

no BLAST hits found

purine nucleotides degradation IV (anaerobic)

Total # of reactions in pathway = 22

Present reactions: 9

Reaction Protein(s)
4.3.1.4-RXN (# # #)
METHENYLTHFCYCLOHYDRO-RXN (# # #)
FORMATETHFLIG-RXN (#)
METHYLENETHFDEHYDROG-NADP-RXN (# #)
GLYOHMETRANS-RXN (#)
4.3.1.17-RXN (# #)
PYRUFLAVREDUCT-RXN NIL
PHOSACETYLTRANS-RXN (#)
ACETATEKIN-RXN (#)

Missing reactions: 13

GUANINE-DEAMINASE-RXN
R127-RXN
R128-RXN
R62-RXN
R13-RXN
R63-RXN
GLYCINE-FORMIMINOTRANSFERASE-RXN
1.2.1.2-RXN
RXN0-901
RXN-8752
RXN-8751
RXN-8754
RXN-8753

Evidence for , EC# EC-3.5.4.3GUANINE-DEAMINASE-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for R127-RXN

Evidence for R128-RXN

Evidence for R62-RXN

Evidence for , EC# EC-3.5.4.8R13-RXN

Evidence for , EC# EC-3.5.2R63-RXN

Evidence for , EC# EC-2.1.2.4GLYCINE-FORMIMINOTRANSFERASE-RXN

no BLAST hits found

Evidence for , EC# EC-1.2.1.21.2.1.2-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-1.17.1.4RXN0-901

no BLAST hits found

Evidence for RXN-8752

Evidence for RXN-8751

Evidence for RXN-8754

Evidence for RXN-8753

purine nucleotides degradation III (anaerobic)

Total # of reactions in pathway = 17

Present reactions: 5

Reaction Protein(s)
4.3.1.4-RXN (# # #)
METHENYLTHFCYCLOHYDRO-RXN (# # #)
FORMATETHFLIG-RXN (#)
RXN-7566 (#)
ACETATEKIN-RXN (#)

Missing reactions: 12

GUANINE-DEAMINASE-RXN
R127-RXN
R128-RXN
R62-RXN
R13-RXN
R63-RXN
GLYCINE-FORMIMINOTRANSFERASE-RXN
1.2.1.2-RXN
RXN0-901
RXN-8752
RXN-8755
RXN-7682

Evidence for , EC# EC-3.5.4.3GUANINE-DEAMINASE-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for R127-RXN

Evidence for R128-RXN

Evidence for R62-RXN

Evidence for , EC# EC-3.5.4.8R13-RXN

Evidence for , EC# EC-3.5.2R63-RXN

Evidence for , EC# EC-2.1.2.4GLYCINE-FORMIMINOTRANSFERASE-RXN

no BLAST hits found

Evidence for , EC# EC-1.2.1.21.2.1.2-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-1.17.1.4RXN0-901

no BLAST hits found

Evidence for RXN-8752

Evidence for RXN-8755

Evidence for , EC# EC-1.17.1.4RXN-7682

no BLAST hits found

purine deoxyribonucleosides degradation

Total # of reactions in pathway = 7

Present reactions: 6

Reaction Protein(s)
DEOXYGUANPHOSPHOR-RXN (#)
DEOXYADENPHOSPHOR-RXN (#)
DEOXYINOPHOSPHOR-RXN (#)
D-PPENTOMUT-RXN (#)
DEOXYRIBOSE-P-ALD-RXN (# #)
ACETALD-DEHYDROG-RXN (# #)

Missing reactions: 1

ADDALT-RXN

Evidence for ADDALT-RXN

no BLAST hits found

ppGpp biosynthesis

Total # of reactions in pathway = 6

Present reactions: 3

Reaction Protein(s)
PPPGPPHYDRO-RXN (#)
GTPPYPHOSKIN-RXN (#)
GDPPYPHOSKIN-RXN (#)

Missing reactions: 3

PPGPPSYN-RXN
RXN0-6427
GDPKIN-RXN

Evidence for , EC# EC-3.1.7.2PPGPPSYN-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for guanosine 3'-diphosphate 5'-triphosphate 3'-diphosphatase, EC# EC-3.1.7.2RXN0-6427

no BLAST hits found

Evidence for , EC# EC-2.7.4.6GDPKIN-RXN

no BLAST hits found

phosphopantothenate biosynthesis II

Total # of reactions in pathway = 3

Present reactions: 1

Reaction Protein(s)
PANTOTHENATE-KIN-RXN (#)

Missing reactions: 2

1.1.1.168-RXN
RXN-6401

Evidence for , EC# EC-1.1.1.1681.1.1.168-RXN

Evidence for , EC# EC-6.3.2RXN-6401

phosphatidylglycerol biosynthesis II (non-plastidic)

Total # of reactions in pathway = 3

Present reactions: 2

Reaction Protein(s)
PWY-5667 NIL
PHOSPHAGLYPSYN-RXN (# #)

Missing reactions: 1

PGPPHOSPHA-RXN

Evidence for , EC# EC-3.1.3.27PGPPHOSPHA-RXN

no BLAST hits found

phenylalanine degradation III

Total # of reactions in pathway = 4

Present reactions: 2

Reaction Protein(s)
PHEAMINOTRANS-RXN (#)
RXN-7700 (#)

Missing reactions: 2

PHENYLPYRUVATE-DECARBOXYLASE-RXN
2.6.1.58-RXN

Evidence for , EC# EC-4.1.1.43PHENYLPYRUVATE-DECARBOXYLASE-RXN

no BLAST hits found

Evidence for , EC# EC-2.6.1.582.6.1.58-RXN

no BLAST hits found

phenylalanine biosynthesis I

Total # of reactions in pathway = 3

Present reactions: 2

Reaction Protein(s)
PHEAMINOTRANS-RXN (#)
CHORISMATEMUT-RXN (#)

Missing reactions: 1

PREPHENATEDEHYDRAT-RXN

Evidence for , EC# EC-4.2.1.51PREPHENATEDEHYDRAT-RXN

no BLAST hits found

peptidoglycan biosynthesis V (β-lactam resistance)

Total # of reactions in pathway = 10

Present reactions: 3

Reaction Protein(s)
PWY-6386 NIL
RXN-11347 (# #)
RXN-11346 (# # #)

Missing reactions: 7

3.4.17.14-RXN
RXN-11345
RXN-11344
RXN-11343
RXN-11348
RXN-11349
2.4.1.129-RXN

Evidence for , EC# EC-3.4.17.143.4.17.14-RXN

no BLAST hits found

Evidence for RXN-11345

Evidence for , EC# EC-6.3.1.12RXN-11344

Evidence for RXN-11343

Evidence for , EC# EC-2.4.1.129RXN-11348

Evidence for , EC# EC-3.4.16RXN-11349

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for Peptidoglycan glycosyltransferase, EC# EC-2.4.1.1292.4.1.129-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

peptidoglycan biosynthesis III (mycobacteria)

Total # of reactions in pathway = 7

Present reactions: 2

Reaction Protein(s)
RXN-11029 (# # #)
PWY-6387 NIL

Missing reactions: 5

RXN-11028
RXN-11030
RXN-11031
RXN-11301
2.4.1.129-RXN

Evidence for , EC# EC-2.7.8RXN-11028

no BLAST hits found

Evidence for RXN-11030

no BLAST hits found

Evidence for RXN-11031

no BLAST hits found

Evidence for , EC# EC-2.4.1RXN-11301

no BLAST hits found

Evidence for Peptidoglycan glycosyltransferase, EC# EC-2.4.1.1292.4.1.129-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

peptidoglycan biosynthesis I (meso-diaminopimelate containing)

Total # of reactions in pathway = 6

Present reactions: 4

Reaction Protein(s)
NACGLCTRANS-RXN (# # #)
PHOSNACMURPENTATRANS-RXN (# #)
RXN-11302 (# # #)
PWY-6387 NIL

Missing reactions: 2

RXN0-5405
2.4.1.129-RXN

Evidence for , EC# EC-2.4.1.129RXN0-5405

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for Peptidoglycan glycosyltransferase, EC# EC-2.4.1.1292.4.1.129-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

NAD/NADH phosphorylation and dephosphorylation

Total # of reactions in pathway = 6

Present reactions: 2

Reaction Protein(s)
NAD-KIN-RXN (# # #)
NADH-DEHYDROG-A-RXN (#)

Missing reactions: 4

PYRNUTRANSHYDROGEN-RXN
NADH-KINASE-RXN
RXN-7703
RXN-5822

Evidence for , EC# EC-1.6.1.1PYRNUTRANSHYDROGEN-RXN

no BLAST hits found

Evidence for , EC# EC-2.7.1.86NADH-KINASE-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-3.1.3RXN-7703

Evidence for NADP phosphatase, EC# EC-3.1.3RXN-5822

no BLAST hits found

NAD salvage pathway I

Total # of reactions in pathway = 8

Present reactions: 3

Reaction Protein(s)
NICONUCADENYLYLTRAN-RXN (#)
NICOTINATEPRIBOSYLTRANS-RXN (#)
NAD-SYNTH-GLN-RXN (#)

Missing reactions: 5

NMNAMIDOHYDRO-RXN
NADPYROPHOSPHAT-RXN
NADNUCLEOSID-RXN
NMNNUCLEOSID-RXN
NICOTINAMID-RXN

Evidence for , EC# EC-3.5.1.42NMNAMIDOHYDRO-RXN

no BLAST hits found

Evidence for , EC# EC-3.6.1.22NADPYROPHOSPHAT-RXN

no BLAST hits found

Evidence for , EC# EC-3.2.2.5NADNUCLEOSID-RXN

no BLAST hits found

Evidence for , EC# EC-3.2.2.14NMNNUCLEOSID-RXN

Evidence for , EC# EC-3.5.1.19NICOTINAMID-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

NAD biosynthesis I (from aspartate)

Total # of reactions in pathway = 6

Present reactions: 4

Reaction Protein(s)
NICONUCADENYLYLTRAN-RXN (#)
NAD-SYNTH-GLN-RXN (#)
NAD-SYNTH-NH3-RXN (#)
QUINOPRIBOTRANS-RXN (#)

Missing reactions: 2

QUINOLINATE-SYNTHA-RXN
L-ASPARTATE-OXID-RXN

Evidence for , EC# EC-2.5.1.72QUINOLINATE-SYNTHA-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-1.4.3.16L-ASPARTATE-OXID-RXN

no BLAST hits found

mixed acid fermentation

Total # of reactions in pathway = 16

Present reactions: 6

Reaction Protein(s)
PHOSACETYLTRANS-RXN (#)
ACETATEKIN-RXN (#)
PYRUVFORMLY-RXN (#)
ACETALD-DEHYDROG-RXN (# #)
ALCOHOL-DEHYDROG-RXN (#)
PEPDEPHOS-RXN (#)

Missing reactions: 10

DLACTDEHYDROGNAD-RXN
FUMHYDR-RXN
PEPCARBOX-RXN
FHLMULTI-RXN
R601-RXN
CITSYN-RXN
ACONITATEDEHYDR-RXN
ACONITATEHYDR-RXN
ISOCITDEH-RXN
MALATE-DEH-RXN

Evidence for , EC# EC-1.1.1.28DLACTDEHYDROGNAD-RXN

no BLAST hits found

Evidence for , EC# EC-4.2.1.2FUMHYDR-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-4.1.1.31PEPCARBOX-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for FHLMULTI-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-1.3.5.4R601-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-2.3.3.1CITSYN-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-4.2.1.3ACONITATEDEHYDR-RXN

no BLAST hits found

Evidence for , EC# EC-4.2.1.3ACONITATEHYDR-RXN

no BLAST hits found

Evidence for , EC# EC-1.1.1.42ISOCITDEH-RXN

no BLAST hits found

Evidence for , EC# EC-1.1.1.37MALATE-DEH-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

methylglyoxal degradation VI

Total # of reactions in pathway = 4

Present reactions: 2

Reaction Protein(s)
RXN-8641 (#)
D-LACTATE-DEHYDROGENASE-CYTOCHROME-RXN NIL

Missing reactions: 2

D-LACTALDEHYDE-DEHYDROGENASE-RXN
LACTALDEHYDE-OXI-RXN

Evidence for , EC# EC-1.1.1.78D-LACTALDEHYDE-DEHYDROGENASE-RXN

Evidence for LACTALDEHYDE-OXI-RXN

no BLAST hits found

methylglyoxal degradation V

Total # of reactions in pathway = 3

Present reactions: 1

Reaction Protein(s)
L-LACTATE-DEHYDROGENASE-CYTOCHROME-RXN (#)

Missing reactions: 2

LACTALDDEHYDROG-RXN
1.1.1.283-RXN

Evidence for , EC# EC-1.2.1.22LACTALDDEHYDROG-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-1.1.1.2831.1.1.283-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

methylerythritol phosphate pathway

Total # of reactions in pathway = 9

Present reactions: 8

Reaction Protein(s)
DXS-RXN (#)
DXPREDISOM-RXN (#)
RXN0-302 (#)
RXN0-882 (#)
RXN0-884 (#)
ISPH2-RXN (#)
2.7.1.148-RXN (#)
2.7.7.60-RXN (#)

Missing reactions: 1

IPPISOM-RXN

Evidence for , EC# EC-5.3.3.2IPPISOM-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

methionine degradation I (to homocysteine)

Total # of reactions in pathway = 3

Present reactions: 2

Reaction Protein(s)
S-ADENMETSYN-RXN (#)
RXN-7605 (#)

Missing reactions: 1

ADENOSYLHOMOCYSTEINASE-RXN

Evidence for , EC# EC-3.3.1.1ADENOSYLHOMOCYSTEINASE-RXN

no BLAST hits found

methionine biosynthesis II

Total # of reactions in pathway = 6

Present reactions: 4

Reaction Protein(s)
HOMOSERKIN-RXN (#)
CYSTATHIONINE-BETA-LYASE-RXN (#)
HOMOCYSTEINE-S-METHYLTRANSFERASE-RXN (#)
MMUM-RXN (#)

Missing reactions: 2

CYSPH-RXN
HOMOCYSMET-RXN

Evidence for , EC# EC-2.5.1CYSPH-RXN

no BLAST hits found

Evidence for , EC# EC-2.1.1.14HOMOCYSMET-RXN

no BLAST hits found

lysine biosynthesis VI

Total # of reactions in pathway = 8

Present reactions: 6

Reaction Protein(s)
ASPARTATEKIN-RXN (#)
ASPARTATE-SEMIALDEHYDE-DEHYDROGENASE-RXN (#)
DIHYDRODIPICSYN-RXN (#)
RXN-7737 (#)
DIAMINOPIMEPIM-RXN (#)
DIHYDROPICRED-RXN (#)

Missing reactions: 2

DIAMINOPIMDECARB-RXN
RXN-13462

Evidence for , EC# EC-4.1.1.20DIAMINOPIMDECARB-RXN

no BLAST hits found

Evidence for (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinate dehydratase, EC# EC-4.2.1RXN-13462

no BLAST hits found

lactose and galactose degradation I

Total # of reactions in pathway = 4

Present reactions: 1

Reaction Protein(s)
LACTOSE-6-PHOSPHATE-ISOMERASE-RXN (#)

Missing reactions: 3

TAGAKIN-RXN
LACTOSE6P-HYDROXY-RXN
TAGAALDOL-RXN

Evidence for , EC# EC-2.7.1.144TAGAKIN-RXN

no BLAST hits found

Evidence for 6-phospho-lactosidase, EC# EC-3.2.1.85LACTOSE6P-HYDROXY-RXN

no BLAST hits found

Evidence for , EC# EC-4.1.2.40TAGAALDOL-RXN

no BLAST hits found

homoserine biosynthesis

Total # of reactions in pathway = 3

Present reactions: 2

Reaction Protein(s)
ASPARTATEKIN-RXN (#)
ASPARTATE-SEMIALDEHYDE-DEHYDROGENASE-RXN (#)

Missing reactions: 1

HOMOSERDEHYDROG-RXN

Evidence for , EC# EC-1.1.1.3HOMOSERDEHYDROG-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

homolactic fermentation

Total # of reactions in pathway = 4

Present reactions: 3

Reaction Protein(s)
PWY-5481 NIL
GLUCOKIN-RXN (# #)
PWY-5484 NIL

Missing reactions: 1

PGLUCISOM-RXN

Evidence for glucose-6-phosphate isomerase, EC# EC-5.3.1.9PGLUCISOM-RXN

no BLAST hits found

histidine degradation I

Total # of reactions in pathway = 4

Present reactions: 3

Reaction Protein(s)
HISTIDINE-AMMONIA-LYASE-RXN (#)
UROCANATE-HYDRATASE-RXN (#)
IMIDAZOLONEPROPIONASE-RXN (# # # #)

Missing reactions: 1

FORMIMINOGLUTAMASE-RXN

Evidence for , EC# EC-3.5.3.8FORMIMINOGLUTAMASE-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

histidine biosynthesis

Total # of reactions in pathway = 10

Present reactions: 2

Reaction Protein(s)
HISTIDPHOS-RXN (# #)
HISTAMINOTRANS-RXN (#)

Missing reactions: 8

HISTALDEHYD-RXN
HISTOLDEHYD-RXN
IMIDPHOSDEHYD-RXN
GLUTAMIDOTRANS-RXN
PRIBFAICARPISOM-RXN
HISTPRATPHYD-RXN
HISTCYCLOHYD-RXN
ATPPHOSPHORIBOSYLTRANS-RXN

Evidence for Histidinal dehydrogenaseHISTALDEHYD-RXN

no BLAST hits found

Evidence for Histidinol dehydrogenaseHISTOLDEHYD-RXN

no BLAST hits found

Evidence for , EC# EC-4.2.1.19IMIDPHOSDEHYD-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-2.4.2GLUTAMIDOTRANS-RXN

no BLAST hits found

Evidence for , EC# EC-5.3.1.16PRIBFAICARPISOM-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-3.6.1.31HISTPRATPHYD-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-3.5.4.19HISTCYCLOHYD-RXN

no BLAST hits found

Evidence for , EC# EC-2.4.2.17ATPPHOSPHORIBOSYLTRANS-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

heterolactic fermentation

Total # of reactions in pathway = 18

Present reactions: 11

Reaction Protein(s)
RIBULP3EPIM-RXN (#)
GAPOXNPHOSPHN-RXN (#)
PHOSGLYPHOS-RXN (#)
3PGAREARR-RXN (# # #)
2PGADEHYDRAT-RXN (#)
PEPDEPHOS-RXN (#)
PHOSACETYLTRANS-RXN (#)
ACETALD-DEHYDROG-RXN (# #)
ALCOHOL-DEHYDROG-RXN (#)
L-LACTATE-DEHYDROGENASE-RXN (#)
GLUCOKIN-RXN (# #)

Missing reactions: 7

6PGLUCONDEHYDROG-RXN
PHOSPHOKETOLASE-RXN
GLU6PDEHYDROG-RXN
6PGLUCONOLACT-RXN
FRUCTOKINASE-RXN
PGLUCISOM-RXN
DLACTDEHYDROGNAD-RXN

Evidence for phosphogluconate dehydrogenase [NAD(P)+-dependent, decarboxylating], EC# EC-1.1.16PGLUCONDEHYDROG-RXN

Evidence for , EC# EC-4.1.2.9PHOSPHOKETOLASE-RXN

no BLAST hits found

Evidence for , EC# EC-1.1.1.49GLU6PDEHYDROG-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-3.1.1.316PGLUCONOLACT-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for fructokinase, EC# EC-2.7.1.4FRUCTOKINASE-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for glucose-6-phosphate isomerase, EC# EC-5.3.1.9PGLUCISOM-RXN

no BLAST hits found

Evidence for , EC# EC-1.1.1.28DLACTDEHYDROGNAD-RXN

no BLAST hits found

heme biosynthesis from uroporphyrinogen-III II

Total # of reactions in pathway = 4

Present reactions: 2

Reaction Protein(s)
PROTOHEMEFERROCHELAT-RXN (#)
HEMN-RXN (#)

Missing reactions: 2

UROGENDECARBOX-RXN
RXN0-6259

Evidence for , EC# EC-4.1.1.37UROGENDECARBOX-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-1.3.5.3RXN0-6259

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

guanosine nucleotides degradation III

Total # of reactions in pathway = 4

Present reactions: 1

Reaction Protein(s)
RXN-7609 (#)

Missing reactions: 3

GUANINE-DEAMINASE-RXN
RXN0-901
RXN0-5199

Evidence for , EC# EC-3.5.4.3GUANINE-DEAMINASE-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-1.17.1.4RXN0-901

no BLAST hits found

Evidence for guanosine phosphorylase, EC# EC-2.4.2.1RXN0-5199

no BLAST hits found

guanosine nucleotides de novo biosynthesis

Total # of reactions in pathway = 9

Present reactions: 6

Reaction Protein(s)
IMP-DEHYDROG-RXN (#)
GMP-SYN-GLUT-RXN (#)
GUANYL-KIN-RXN (#)
GDPREDUCT-RXN NIL
RXN0-746 NIL
RXN0-748 NIL

Missing reactions: 3

GMP-SYN-NH3-RXN
GDPKIN-RXN
DGDPKIN-RXN

Evidence for , EC# EC-6.3.4.1GMP-SYN-NH3-RXN

no BLAST hits found

Evidence for , EC# EC-2.7.4.6GDPKIN-RXN

no BLAST hits found

Evidence for , EC# EC-2.7.4.6DGDPKIN-RXN

no BLAST hits found

guanine and guanosine salvage I

Total # of reactions in pathway = 2

Present reactions: 1

Reaction Protein(s)
GUANPRIBOSYLTRAN-RXN (# #)

Missing reactions: 1

RXN0-5199

Evidence for guanosine phosphorylase, EC# EC-2.4.2.1RXN0-5199

no BLAST hits found

glycolysis III (glucokinase)

Total # of reactions in pathway = 10

Present reactions: 9

Reaction Protein(s)
GLUCOKIN-RXN (# #)
6PFRUCTPHOS-RXN (#)
F16ALDOLASE-RXN (#)
TRIOSEPISOMERIZATION-RXN (#)
GAPOXNPHOSPHN-RXN (#)
PHOSGLYPHOS-RXN (#)
3PGAREARR-RXN (# # #)
2PGADEHYDRAT-RXN (#)
PEPDEPHOS-RXN (#)

Missing reactions: 1

PGLUCISOM-RXN

Evidence for glucose-6-phosphate isomerase, EC# EC-5.3.1.9PGLUCISOM-RXN

no BLAST hits found

glycogen degradation II

Total # of reactions in pathway = 5

Present reactions: 2

Reaction Protein(s)
GLYCOPHOSPHORYL-RXN (# #)
RXN-9025 (# #)

Missing reactions: 3

3.2.1.33-RXN
RXN-9023
PHOSPHOGLUCMUT-RXN

Evidence for , EC# EC-3.2.1.333.2.1.33-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-2.4.1.25RXN-9023

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-5.4.2.2PHOSPHOGLUCMUT-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

glycogen degradation I

Total # of reactions in pathway = 7

Present reactions: 4

Reaction Protein(s)
GLYCOPHOSPHORYL-RXN (# #)
RXN0-5182 (# #)
RXN0-5183 (# # #)
GLUCOKIN-RXN (# #)

Missing reactions: 3

AMYLOMALT-RXN
PHOSPHOGLUCMUT-RXN
RXN0-5146

Evidence for 4-α-glucanotransferase, EC# EC-2.4.1.25AMYLOMALT-RXN

no BLAST hits found

Evidence for , EC# EC-5.4.2.2PHOSPHOGLUCMUT-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-3.2.1.33RXN0-5146

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

glycerol-3-phosphate shuttle

Total # of reactions in pathway = 2

Present reactions: 1

Reaction Protein(s)
RXN0-5260 (#)

Missing reactions: 1

1.1.1.8-RXN

Evidence for , EC# EC-1.1.1.81.1.1.8-RXN

no BLAST hits found

gluconeogenesis I

Total # of reactions in pathway = 12

Present reactions: 8

Reaction Protein(s)
F16BDEPHOS-RXN (# #)
F16ALDOLASE-RXN (#)
GAPOXNPHOSPHN-RXN (#)
PHOSGLYPHOS-RXN (#)
3PGAREARR-RXN (# # #)
2PGADEHYDRAT-RXN (#)
PEPCARBOXYKIN-RXN (#)
PEPSYNTH-RXN (#)

Missing reactions: 4

PGLUCISOM-RXN
MALATE-DEH-RXN
MALIC-NAD-RXN
MALIC-NADP-RXN

Evidence for glucose-6-phosphate isomerase, EC# EC-5.3.1.9PGLUCISOM-RXN

no BLAST hits found

Evidence for , EC# EC-1.1.1.37MALATE-DEH-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-1.1.1.38MALIC-NAD-RXN

no BLAST hits found

Evidence for , EC# EC-1.1.1.40MALIC-NADP-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

formylTHF biosynthesis I

Total # of reactions in pathway = 12

Present reactions: 7

Reaction Protein(s)
FORMATETHFLIG-RXN (#)
METHENYLTHFCYCLOHYDRO-RXN (# # #)
GLYOHMETRANS-RXN (#)
METHYLENETHFDEHYDROG-NADP-RXN (# #)
1.5.1.20-RXN (#)
HOMOCYSMETB12-RXN (# #)
5-FORMYL-THF-CYCLO-LIGASE-RXN (#)

Missing reactions: 5

FORMYLTHFDEFORMYL-RXN
DIHYDROFOLATEREDUCT-RXN
GCVMULTI-RXN
THYMIDYLATESYN-RXN
DIHYDROFOLATESYNTH-RXN

Evidence for formyltetrahydrofolate deformylase, EC# EC-3.5.1.10FORMYLTHFDEFORMYL-RXN

no BLAST hits found

Evidence for , EC# EC-1.5.1.3DIHYDROFOLATEREDUCT-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for GCVMULTI-RXN

no BLAST hits found

Evidence for , EC# EC-2.1.1.45THYMIDYLATESYN-RXN

no BLAST hits found

Evidence for , EC# EC-6.3.2.12DIHYDROFOLATESYNTH-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

folate transformations II

Total # of reactions in pathway = 11

Present reactions: 7

Reaction Protein(s)
GLYOHMETRANS-RXN (#)
METHYLENETHFDEHYDROG-NADP-RXN (# #)
METHENYLTHFCYCLOHYDRO-RXN (# # #)
FORMATETHFLIG-RXN (#)
1.5.1.20-RXN (#)
5-FORMYL-THF-CYCLO-LIGASE-RXN (#)
HOMOCYSMETB12-RXN (# #)

Missing reactions: 4

DIHYDROFOLATEREDUCT-RXN
GCVMULTI-RXN
THYMIDYLATESYN-RXN
RXN-6321

Evidence for , EC# EC-1.5.1.3DIHYDROFOLATEREDUCT-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for GCVMULTI-RXN

no BLAST hits found

Evidence for , EC# EC-2.1.1.45THYMIDYLATESYN-RXN

no BLAST hits found

Evidence for RXN-6321

no BLAST hits found

folate transformations I

Total # of reactions in pathway = 12

Present reactions: 8

Reaction Protein(s)
FORMATETHFLIG-RXN (#)
METHENYLTHFCYCLOHYDRO-RXN (# # #)
GLYOHMETRANS-RXN (#)
METHYLENETHFDEHYDROG-NADP-RXN (# #)
HOMOCYSMETB12-RXN (# #)
1.5.1.20-RXN (#)
5-FORMYL-THF-CYCLO-LIGASE-RXN (#)
RXN-5061 NIL

Missing reactions: 4

FORMYLTHFDEFORMYL-RXN
GCVMULTI-RXN
2.1.1.19-RXN
1.5.1.15-RXN

Evidence for formyltetrahydrofolate deformylase, EC# EC-3.5.1.10FORMYLTHFDEFORMYL-RXN

no BLAST hits found

Evidence for GCVMULTI-RXN

no BLAST hits found

Evidence for , EC# EC-2.1.1.192.1.1.19-RXN

Evidence for , EC# EC-1.5.1.151.5.1.15-RXN

no BLAST hits found

fluoroacetate and fluorothreonine biosynthesis

Total # of reactions in pathway = 6

Present reactions: 1

Reaction Protein(s)
RXN-11743 (#)

Missing reactions: 5

RXN-11747
RXN-11744
RXN-11745
2.5.1.63-RXN
RXN-11746

Evidence for , EC# EC-2.2.1.8RXN-11747

no BLAST hits found

Evidence for 5-fluoro-5-deoxy-D-ribose-1-phosphate isomerase, EC# EC-5.3.1RXN-11744

no BLAST hits found

Evidence for 5-fluoro-5-deoxy-d-ribulose-1-phosphate aldolaseRXN-11745

Evidence for , EC# EC-2.5.1.632.5.1.63-RXN

no BLAST hits found

Evidence for , EC# EC-1.2.1.69RXN-11746

Entner-Doudoroff pathway III (semi-phosphorylative)

Total # of reactions in pathway = 9

Present reactions: 5

Reaction Protein(s)
DEOXYGLUCONOKIN-RXN (# # #)
3PGAREARR-RXN (# # #)
2PGADEHYDRAT-RXN (#)
PEPDEPHOS-RXN (#)
KDPGALDOL-RXN (#)

Missing reactions: 4

GLUCOSE-1-DEHYDROGENASE-RXN
GLUCONOLACT-RXN
GLUCONATE-DEHYDRATASE-RXN
RXN-3443

Evidence for , EC# EC-1.1.1.47GLUCOSE-1-DEHYDROGENASE-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-3.1.1.17GLUCONOLACT-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-4.2.1.39GLUCONATE-DEHYDRATASE-RXN

no BLAST hits found

Evidence for , EC# EC-1.2.1.3RXN-3443

Entner-Doudoroff pathway I

Total # of reactions in pathway = 2

Present reactions: 1

Reaction Protein(s)
KDPGALDOL-RXN (#)

Missing reactions: 1

PGLUCONDEHYDRAT-RXN

Evidence for , EC# EC-4.2.1.12PGLUCONDEHYDRAT-RXN

no BLAST hits found

chitin degradation II

Total # of reactions in pathway = 5

Present reactions: 3

Reaction Protein(s)
3.2.1.14-RXN (#)
RXN-12623 (#)
RXN-12624 (#)

Missing reactions: 2

RXN-12625
RXN-12626

Evidence for N,N'-diacetylchitobiose β-N-acetylglucosaminidase, EC# EC-3.2.1.52RXN-12625

no BLAST hits found

Evidence for chitotriose β-N-acetylglucosaminidase, EC# EC-3.2.1.52RXN-12626

no BLAST hits found

cardiolipin biosynthesis I

Total # of reactions in pathway = 3

Present reactions: 2

Reaction Protein(s)
CARDIOLIPSYN-RXN (# #)
PHOSPHAGLYPSYN-RXN (# #)

Missing reactions: 1

PGPPHOSPHA-RXN

Evidence for , EC# EC-3.1.3.27PGPPHOSPHA-RXN

no BLAST hits found

biotin biosynthesis from 7-keto-8-aminopelargonate

Total # of reactions in pathway = 3

Present reactions: 1

Reaction Protein(s)
2.8.1.6-RXN (# #)

Missing reactions: 2

DETHIOBIOTIN-SYN-RXN
DAPASYN-RXN

Evidence for , EC# EC-6.3.3.3DETHIOBIOTIN-SYN-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-2.6.1.62DAPASYN-RXN

no BLAST hits found

arginine degradation X (arginine monooxygenase pathway)

Total # of reactions in pathway = 3

Present reactions: 2

Reaction Protein(s)
GUANIDINOBUTANAMIDE-NH3-RXN (# # # #)
ARGININE-2-MONOOXYGENASE-RXN (#)

Missing reactions: 1

GUANIDINOBUTYRASE-RXN

Evidence for , EC# EC-3.5.3.7GUANIDINOBUTYRASE-RXN

no BLAST hits found

arginine biosynthesis II (acetyl cycle)

Total # of reactions in pathway = 9

Present reactions: 4

Reaction Protein(s)
N-ACETYLGLUTPREDUCT-RXN (#)
GLUTAMATE-N-ACETYLTRANSFERASE-RXN (#)
CARBPSYN-RXN (# #)
N-ACETYLTRANSFER-RXN (#)

Missing reactions: 5

ARGSUCCINSYN-RXN
ARGSUCCINLYA-RXN
ORNCARBAMTRANSFER-RXN
ACETYLORNTRANSAM-RXN
ACETYLGLUTKIN-RXN

Evidence for , EC# EC-6.3.4.5ARGSUCCINSYN-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-4.3.2.1ARGSUCCINLYA-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-2.1.3.3ORNCARBAMTRANSFER-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-2.6.1.11ACETYLORNTRANSAM-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-2.7.2.8ACETYLGLUTKIN-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

alanine biosynthesis I

Total # of reactions in pathway = 3

Present reactions: 1

Reaction Protein(s)
ALARACECAT-RXN (# # # #)

Missing reactions: 2

BRANCHED-CHAINAMINOTRANSFERVAL-RXN
VALINE-PYRUVATE-AMINOTRANSFER-RXN

Evidence for Valine transaminase, EC# EC-2.6.1.42BRANCHED-CHAINAMINOTRANSFERVAL-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-2.6.1.66VALINE-PYRUVATE-AMINOTRANSFER-RXN

no BLAST hits found

adenosylcobalamin salvage from cobinamide I

Total # of reactions in pathway = 6

Present reactions: 5

Reaction Protein(s)
COBINPGUANYLYLTRANS-RXN (#)
COBINAMIDEKIN-RXN (#)
DMBPPRIBOSYLTRANS-RXN (#)
BTUR2-RXN (#)
COBALAMIN5PSYN-RXN (#)

Missing reactions: 1

RXN-8770

Evidence for , EC# EC-3.1.3.73RXN-8770

no BLAST hits found

adenosylcobalamin biosynthesis I (early cobalt insertion)

Total # of reactions in pathway = 14

Present reactions: 5

Reaction Protein(s)
RXN-8769 (#)
RXN-8675 (# #)
UROPORIIIMETHYLTRANSA-RXN (# #)
RXN-8759 (#)
PWY-5509 NIL

Missing reactions: 9

RXN-8763
RXN-8765
RXN-8768
RXN-8760
RXN-8761
RXN-8762
RXN-8764
RXN-8766
RXN-8767

Evidence for , EC# EC-3.7.1.12RXN-8763

no BLAST hits found

Evidence for RXN-8765

no BLAST hits found

Evidence for RXN-8768

no BLAST hits found

Evidence for Cobalt-precorrin-2 C(20)-methyltransferase, EC# EC-2.1.1.151RXN-8760

no BLAST hits found

Evidence for cobalt-precorrin-3 (C17)-methyltransferase, EC# EC-2.1.1.131RXN-8761

no BLAST hits found

Evidence for cobalt precorrin-4 (C11)-methyltransferase, EC# EC-2.1.1.133RXN-8762

no BLAST hits found

Evidence for , EC# EC-2.1.1.195RXN-8764

no BLAST hits found

Evidence for cobalt-precorrin-6B methylase, EC# EC-2.1.1RXN-8766

no BLAST hits found

Evidence for , EC# EC-2.1.1.196RXN-8767

adenosylcobalamin biosynthesis from cobyrinate a,c-diamide I

Total # of reactions in pathway = 8

Present reactions: 5

Reaction Protein(s)
R344-RXN (#)
R345-RXN (#)
COBINPGUANYLYLTRANS-RXN (#)
COBALAMIN5PSYN-RXN (#)
DMBPPRIBOSYLTRANS-RXN (#)

Missing reactions: 3

R343-RXN
RXN-6261
RXN-8770

Evidence for , EC# EC-1.16.8.1R343-RXN

Hit Common P #Q Best Qry Best Eval Avg Rank Aln Len Qry Len IDOP? adj?

Evidence for , EC# EC-6.3.1.10RXN-6261

no BLAST hits found

Evidence for , EC# EC-3.1.3.73RXN-8770

no BLAST hits found

adenosine nucleotides degradation I

Total # of reactions in pathway = 8

Present reactions: 4

Reaction Protein(s)
IMP-DEHYDROG-RXN (#)
XMPXAN-RXN (#)
RXN-7607 (#)
INOSINE-NUCLEOSIDASE-RXN (#)

Missing reactions: 4

AMP-DEAMINASE-RXN
RXN0-363
RXN0-901
RXN-7682

Evidence for , EC# EC-3.5.4.6AMP-DEAMINASE-RXN

no BLAST hits found

Evidence for , EC# EC-3.2.2.1RXN0-363

no BLAST hits found

Evidence for , EC# EC-1.17.1.4RXN0-901

no BLAST hits found

Evidence for , EC# EC-1.17.1.4RXN-7682

no BLAST hits found

adenosine nucleotides de novo biosynthesis

Total # of reactions in pathway = 8

Present reactions: 7

Reaction Protein(s)
ADENYLOSUCCINATE-SYNTHASE-RXN (#)
AMPSYN-RXN (#)
ADENYL-KIN-RXN (#)
ADPREDUCT-RXN (#)
RXN0-745 NIL
RXN0-747 NIL
ATPSYN-RXN (# # # # # # # # # # #)

Missing reactions: 1

DADPKIN-RXN

Evidence for , EC# EC-2.7.4.6DADPKIN-RXN

no BLAST hits found

adenine and adenosine salvage I

Total # of reactions in pathway = 2

Present reactions: 1

Reaction Protein(s)
ADENPRIBOSYLTRAN-RXN (#)

Missing reactions: 1

ADENPHOSPHOR-RXN

Evidence for adenosine phosphorylase, EC# EC-2.4.2.1ADENPHOSPHOR-RXN

no BLAST hits found

S-methyl-5'-thioadenosine degradation III

Total # of reactions in pathway = 2

Present reactions: 1

Reaction Protein(s)
RXN-10035 (#)

Missing reactions: 1

RXN-12241

Evidence for , EC# EC-2.4.2.44RXN-12241

no BLAST hits found

S-adenosyl-L-methionine cycle I

Total # of reactions in pathway = 5

Present reactions: 4

Reaction Protein(s)
ADENOSYLHOMOCYSTEINE-NUCLEOSIDASE-RXN (#)
RIBOSYLHOMOCYSTEINASE-RXN (#)
SAM-PWY NIL
RXN-7605 (#)

Missing reactions: 1

HOMOCYSMET-RXN

Evidence for , EC# EC-2.1.1.14HOMOCYSMET-RXN

no BLAST hits found

N-acetylneuraminate and N-acetylmannosamine degradation

Total # of reactions in pathway = 3

Present reactions: 2

Reaction Protein(s)
NANE-RXN (#)
ACNEULY-RXN (#)

Missing reactions: 1

NANK-RXN

Evidence for , EC# EC-2.7.1.60NANK-RXN

no BLAST hits found

N-acetylglucosamine degradation II

Total # of reactions in pathway = 4

Present reactions: 3

Reaction Protein(s)
GLUCOSAMINE-6-P-DEAMIN-RXN (#)
NAG6PDEACET-RXN (#)
GLUAMCAT-PWY NIL

Missing reactions: 1

N-ACETYLGLUCOSAMINE-KINASE-RXN

Evidence for , EC# EC-2.7.1.59N-ACETYLGLUCOSAMINE-KINASE-RXN

no BLAST hits found

6-hydroxymethyl-dihydropterin diphosphate biosynthesis I

Total # of reactions in pathway = 5

Present reactions: 3

Reaction Protein(s)
H2PTERIDINEPYROPHOSPHOKIN-RXN (#)
H2NEOPTERINALDOL-RXN (#)
GTP-CYCLOHYDRO-I-RXN (#)

Missing reactions: 2

DIHYDRONEOPTERIN-MONO-P-DEPHOS-RXN
H2NEOPTERINP3PYROPHOSPHOHYDRO-RXN

Evidence for , EC# EC-3.6.1DIHYDRONEOPTERIN-MONO-P-DEPHOS-RXN

Evidence for , EC# EC-3.6.1H2NEOPTERINP3PYROPHOSPHOHYDRO-RXN

no BLAST hits found

β-D-glucuronide and D-glucuronate degradation

Total # of reactions in pathway = 5

Present reactions: 4

Reaction Protein(s)
MANNONDEHYDRAT-RXN (# #)
DEOXYGLUCONOKIN-RXN (# # #)
MANNONOXIDOREDUCT-RXN (#)
GLUCUROISOM-RXN (# #)

Missing reactions: 1

BETA-GLUCURONID-RXN

Evidence for , EC# EC-3.2.1.31BETA-GLUCURONID-RXN

no BLAST hits found