"ID","GSE33630","GSE3467","GSE3678","change","Representative Public ID","Alignments","Gene Title","Gene Symbol","Ensembl","Entrez Gene","OMIM","RefSeq Protein ID","RefSeq Transcript ID","Gene Ontology Biological Process","Gene Ontology Cellular Component","Gene Ontology Molecular Function","Pathway","InterPro"
"1552626_a_at",1.671019188,1.336742058,2.525761453,"UP","NM_030923","chr2:135213560-135476566 (-) // 94.96 // q21.3","transmembrane protein 163","TMEM163","ENSG00000152128 /// OTTHUMG00000131713","81615","---","NP_112185","NM_030923","---","0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030285 // integral component of synaptic vesicle membrane // inferred from sequence or structural similarity /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation","0008270 // zinc ion binding // inferred from sequence or structural similarity","---","---"
"1552826_at",-2.186316924,-2.117485531,-2.848685322,"DOWN","NM_134266","chr8:92261515-92406946 (+) // 98.96 // q21.3","solute carrier family 26 (anion exchanger), member 7","SLC26A7","ENSG00000147606 /// OTTHUMG00000164062","115111","608479","NP_001269285 /// NP_001269286 /// NP_439897 /// NP_599028","NM_001282356 /// NM_001282357 /// NM_052832 /// NM_134266","0001696 // gastric acid secretion // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006820 // anion transport // inferred from direct assay /// 0006821 // chloride transport // inferred from direct assay /// 0008272 // sulfate transport // inferred from direct assay /// 0015701 // bicarbonate transport // inferred from sequence or structural similarity /// 0019532 // oxalate transport // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 1902358 // sulfate transmembrane transport // inferred from direct assay /// 1902358 // sulfate transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from direct assay /// 1902476 // chloride transmembrane transport // inferred from electronic annotation","0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from mutant phenotype /// 0055038 // recycling endosome membrane // inferred from electronic annotation","0005253 // anion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from direct assay /// 0015106 // bicarbonate transmembrane transporter activity // inferred from sequence or structural similarity /// 0015116 // sulfate transmembrane transporter activity // inferred from direct assay /// 0015301 // anion:anion antiporter activity // inferred from electronic annotation /// 0019531 // oxalate transmembrane transporter activity // inferred from direct assay","---","IPR002645 // STAS domain // 1.4E-22 /// IPR011547 // Sulphate transporter // 1.1E-67"
"1552827_s_at",-2.126414861,-1.895038582,-1.257224652,"DOWN","NM_134266","chr8:92261515-92406946 (+) // 98.96 // q21.3","solute carrier family 26 (anion exchanger), member 7","SLC26A7","ENSG00000147606 /// OTTHUMG00000164062","115111","608479","NP_001269285 /// NP_001269286 /// NP_439897 /// NP_599028","NM_001282356 /// NM_001282357 /// NM_052832 /// NM_134266","0001696 // gastric acid secretion // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006820 // anion transport // inferred from direct assay /// 0006821 // chloride transport // inferred from direct assay /// 0008272 // sulfate transport // inferred from direct assay /// 0015701 // bicarbonate transport // inferred from sequence or structural similarity /// 0019532 // oxalate transport // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 1902358 // sulfate transmembrane transport // inferred from direct assay /// 1902358 // sulfate transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from direct assay /// 1902476 // chloride transmembrane transport // inferred from electronic annotation","0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from mutant phenotype /// 0055038 // recycling endosome membrane // inferred from electronic annotation","0005253 // anion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from direct assay /// 0015106 // bicarbonate transmembrane transporter activity // inferred from sequence or structural similarity /// 0015116 // sulfate transmembrane transporter activity // inferred from direct assay /// 0015301 // anion:anion antiporter activity // inferred from electronic annotation /// 0019531 // oxalate transmembrane transporter activity // inferred from direct assay","---","IPR002645 // STAS domain // 1.4E-22 /// IPR011547 // Sulphate transporter // 1.1E-67"
"1553589_a_at",2.714734923,2.475559863,1.105528349,"UP","NM_005764","chr1:47649642-47655604 (-) // 100.0 // p33","PDZK1 interacting protein 1","PDZK1IP1","ENSG00000162366 /// OTTHUMG00000007852","10158","607178","NP_005755","NM_005764","---","0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","---","---","---"
"1554748_at",-2.241644351,-1.716952282,-1.847952212,"DOWN","BC020873","chr1:16370248-16383802 (+) // 96.48 // p36.13","chloride channel, voltage-sensitive Kb","CLCNKB","ENSG00000184908 /// OTTHUMG00000009530","1188","602023 /// 607364 /// 613090","NP_000076 /// NP_001159417 /// XP_005245790 /// XP_006710132 /// XP_006710133","NM_000085 /// NM_001165945 /// XM_005245733 /// XM_006710069 /// XM_006710070","0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0007588 // excretion // traceable author statement /// 0034220 // ion transmembrane transport // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // inferred from electronic annotation /// 0044070 // regulation of anion transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation","0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation","0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0030554 // adenyl nucleotide binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000644 // CBS domain // 1.7E-8 /// IPR000644 // CBS domain // 1.0E-9 /// IPR000644 // CBS domain // 1.2E-8 /// IPR000644 // CBS domain // 7.2E-10 /// IPR001807 // Chloride channel, voltage gated // 2.6E-73 /// IPR001807 // Chloride channel, voltage gated // 3.6E-48"
"1554921_a_at",1.71226343,1.093476826,1.215128914,"UP","BC020726","chr13:78109858-78208558 (+) // 97.3 // q22.3","sciellin","SCEL","ENSG00000136155 /// OTTHUMG00000017107","8796","604112","NP_001154178 /// NP_003834 /// NP_659001 /// XP_005266635 /// XP_006719945 /// XP_006719946 /// XP_006719947 /// XP_006719948 /// XP_006719949","NM_001160706 /// NM_003843 /// NM_144777 /// XM_005266578 /// XM_006719882 /// XM_006719883 /// XM_006719884 /// XM_006719885 /// XM_006719886","0008544 // epidermis development // inferred from sequence or structural similarity /// 0008544 // epidermis development // traceable author statement /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0030216 // keratinocyte differentiation // inferred from direct assay","0001533 // cornified envelope // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","---"
"1555950_a_at",1.157206352,1.611382881,2.011836738,"UP","CA448665","chr1:207494852-207510756 (+) // 74.17 // q32.2","CD55 molecule, decay accelerating factor for complement (Cromer blood group)","CD55","ENSG00000196352 /// OTTHUMG00000036255","1604","125240 /// 613793","NP_000565 /// NP_001108224 /// XP_005273134","NM_000574 /// NM_001114543 /// NM_001114544 /// NM_001114752 /// XM_005273077","0002376 // immune system process // inferred from electronic annotation /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0009615 // response to virus // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0031664 // regulation of lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0035743 // CD4-positive, alpha-beta T cell cytokine production // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045730 // respiratory burst // non-traceable author statement /// 0045916 // negative regulation of complement activation // inferred from direct assay /// 0060137 // maternal process involved in parturition // inferred from electronic annotation /// 2000516 // positive regulation of CD4-positive, alpha-beta T cell activation // inferred from direct assay /// 2000563 // positive regulation of CD4-positive, alpha-beta T cell proliferation // inferred from direct assay","0005576 // extracellular region // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0001618 // virus receptor activity // inferred from direct assay /// 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from direct assay","Complement_Activation_Classical // GenMAPP","IPR000436 // Sushi/SCR/CCP // 7.9E-11 /// IPR000436 // Sushi/SCR/CCP // 4.1E-15 /// IPR000436 // Sushi/SCR/CCP // 9.8E-13 /// IPR000436 // Sushi/SCR/CCP // 1.0E-16 /// IPR000436 // Sushi/SCR/CCP // 9.9E-11 /// IPR000436 // Sushi/SCR/CCP // 5.1E-15 /// IPR000436 // Sushi/SCR/CCP // 1.2E-12 /// IPR000436 // Sushi/SCR/CCP // 1.3E-16 /// IPR000436 // Sushi/SCR/CCP // 6.0E-11 /// IPR000436 // Sushi/SCR/CCP // 7.4E-13 /// IPR000436 // Sushi/SCR/CCP // 7.5E-17 /// IPR000436 // Sushi/SCR/CCP // 9.7E-11 /// IPR000436 // Sushi/SCR/CCP // 5.0E-15 /// IPR000436 // Sushi/SCR/CCP // 1.2E-16 /// IPR000436 // Sushi/SCR/CCP // 1.1E-11"
"1557107_at",-2.722985965,-2.460361672,-3.230562489,"DOWN","BC037315","chr7:107297085-107302192 (-) // 72.09 // q22.3","SLC26A4 antisense RNA 1","SLC26A4-AS1","ENSG00000233705 /// OTTHUMG00000154777","286002","---","---","NR_028137","---","---","---","---","---"
"1557122_s_at",3.812018616,2.624814202,4.086614255,"UP","BC036592","chr5:160716256-160719560 (-) // 94.14 // q34","gamma-aminobutyric acid (GABA) A receptor, beta 2","GABRB2","ENSG00000145864 /// OTTHUMG00000130349","2561","600232","NP_000804 /// NP_068711","NM_000813 /// NM_021911","0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007214 // gamma-aminobutyric acid signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0051932 // synaptic transmission, GABAergic // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 0060119 // inner ear receptor cell development // inferred from electronic annotation /// 0060384 // innervation // inferred from electronic annotation /// 0071420 // cellular response to histamine // inferred from sequence or structural similarity /// 0090102 // cochlea development // inferred from electronic annotation /// 1901215 // negative regulation of neuron death // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation","0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 1902711 // GABA-A receptor complex // inferred from sequence or structural similarity","0004890 // GABA-A receptor activity // inferred from sequence or structural similarity /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005237 // inhibitory extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation","---","IPR006029 // Neurotransmitter-gated ion-channel transmembrane domain // 9.7E-57 /// IPR006202 // Neurotransmitter-gated ion-channel ligand-binding // 6.0E-56"
"1557761_s_at",1.053647022,1.383555316,3.3077794,"UP","BC020945","chr1:165451585-165551388 (-) // 74.51 // q23.3","uncharacterized LOC400794","LOC400794","ENSG00000237463 /// OTTHUMG00000034624","400794","---","---","NR_026744","---","---","---","---","---"
"1558077_s_at",-1.309079528,-1.052342046,-1.473449734,"DOWN","BG202523","chr2:207602803-207630050 (-) // 99.26 // q33.3","malate dehydrogenase 1B, NAD (soluble)","MDH1B","ENSG00000138400 /// OTTHUMG00000132918","130752","---","NP_001034934 /// NP_001269869 /// XP_005246372 /// XP_005246373","NM_001039845 /// NM_001282940 /// NM_206892 /// NR_104261 /// XM_005246315 /// XM_005246316","0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006108 // malate metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation","---","0003824 // catalytic activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016615 // malate dehydrogenase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation","---","IPR022383 // Lactate/malate dehydrogenase, C-terminal // 4.1E-9"
"1558487_a_at",-1.275825336,-1.04628253,-1.307603552,"DOWN","AK074557","chr7:44620076-44621816 (-) // 39.51 // p13","transmembrane emp24 protein transport domain containing 4","TMED4","ENSG00000158604 /// OTTHUMG00000129210","222068","612038","NP_872353","NM_182547","0006810 // transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype","0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0004871 // signal transducer activity // inferred from mutant phenotype","---","IPR009038 // GOLD // 5.0E-36"
"1558815_at",-1.041195317,-1.206434718,-1.050800596,"DOWN","BC035329","chr4:186695157-186877513 (-) // 93.79 // q35.1","sorbin and SH3 domain containing 2","SORBS2","ENSG00000154556 /// OTTHUMG00000157215","8470","---","NP_001139142 /// NP_001139143 /// NP_001139144 /// NP_001139145 /// NP_001139146 /// NP_001139147 /// NP_001257700 /// NP_003594 /// NP_066547 /// XP_005263359 /// XP_005263362 /// XP_005263363 /// XP_005263364 /// XP_005263365 /// XP_005263367 /// XP_005263368 /// XP_005263369 /// XP_005263370 /// XP_006714408 /// XP_006714409 /// XP_006714410 /// XP_006714411 /// XP_006714412 /// XP_006714413 /// XP_006714414 /// XP_006714415 /// XP_006714416 /// XP_006714417 /// XP_006714418 /// XP_006714419 /// XP_006714420 /// XP_006714421 /// XP_006714422 /// XP_006714423 /// XP_006714424 /// XP_006714425 /// XP_006714426 /// XP_006714427 /// XP_006714428 /// XP_006714429 /// XP_006714430 /// XP_006714431 /// XP_006714432 /// XP_006714433 /// XP_006714434 /// XP_006714435 /// XP_006714436 /// XP_006714437 /// XP_006714438 /// XP_006714439 /// XP_006714440 /// XP_006714441 /// XP_006714442 /// XP_006714443 /// XP_006714444 /// XP_006714445 /// XP_006714446 /// XP_006714447 /// XP_006714448 /// XP_006714449 /// XP_006714450 /// XP_006714451 /// XP_006714452 /// XP_006714453","NM_001145670 /// NM_001145671 /// NM_001145672 /// NM_001145673 /// NM_001145674 /// NM_001145675 /// NM_001270771 /// NM_003603 /// NM_021069 /// XM_005263302 /// XM_005263305 /// XM_005263306 /// XM_005263307 /// XM_005263308 /// XM_005263310 /// XM_005263311 /// XM_005263312 /// XM_005263313 /// XM_006714345 /// XM_006714346 /// XM_006714347 /// XM_006714348 /// XM_006714349 /// XM_006714350 /// XM_006714351 /// XM_006714352 /// XM_006714353 /// XM_006714354 /// XM_006714355 /// XM_006714356 /// XM_006714357 /// XM_006714358 /// XM_006714359 /// XM_006714360 /// XM_006714361 /// XM_006714362 /// XM_006714363 /// XM_006714364 /// XM_006714365 /// XM_006714366 /// XM_006714367 /// XM_006714368 /// XM_006714369 /// XM_006714370 /// XM_006714371 /// XM_006714372 /// XM_006714373 /// XM_006714374 /// XM_006714375 /// XM_006714376 /// XM_006714377 /// XM_006714378 /// XM_006714379 /// XM_006714380 /// XM_006714381 /// XM_006714382 /// XM_006714383 /// XM_006714384 /// XM_006714385 /// XM_006714386 /// XM_006714387 /// XM_006714388 /// XM_006714389 /// XM_006714390","0007015 // actin filament organization // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation","0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030018 // Z disc // non-traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation","0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // traceable author statement /// 0008307 // structural constituent of muscle // traceable author statement /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation","---","---"
"1560652_at",-1.969638164,-1.618692455,-2.483767952,"DOWN","AL832136","chrX:107963181-107968174 (-) // 91.02 // q22.3","---","RP6-24A23.7","ENSG00000261409 /// OTTHUMG00000175497","---","---","---","---","---","---","---","---","---"
"1569582_at",-2.301378152,-1.051960992,-2.252874938,"DOWN","BC014344","chr3:151488247-151502682 (+) // 96.09 // q25.1","arylacetamide deacetylase pseudogene 1","AADACP1","ENSG00000240602 /// OTTHUMG00000159879","201651","---","---","NR_026915","---","---","---","---","---"
"1570289_at",-2.733631163,-1.499684073,-3.699109827,"DOWN","BC017935","chr2:227007509-227044778 (+) // 49.33 // q36.3","uncharacterized LOC646736","LOC646736","---","646736","---","---","NR_046102","---","---","---","---","---"
"200660_at",1.320295678,1.149127269,1.148632726,"UP","NM_005620","chr1:152004981-152009511 (-) // 99.83 // q21.3","S100 calcium binding protein A11","S100A11","ENSG00000163191 /// OTTHUMG00000013069","6282","603114","NP_005611","NM_005620","0007165 // signal transduction // traceable author statement /// 0008156 // negative regulation of DNA replication // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation","0001726 // ruffle // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044548 // S100 protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from direct assay","---","IPR002048 // EF-hand domain // 1.2E-10 /// IPR013787 // S100/CaBP-9k-type, calcium binding, subdomain // 4.8E-23"
"200701_at",1.298944164,1.121651864,1.461186059,"UP","NM_006432","chr14:74946650-74959983 (-) // 97.4 // q24.3","Niemann-Pick disease, type C2","NPC2","ENSG00000119655 /// OTTHUMG00000171212","10577","601015 /// 607625","NP_006423 /// XP_006720067","NM_006432 /// XM_006720004","0006629 // lipid metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0009615 // response to virus // inferred from expression pattern /// 0015914 // phospholipid transport // traceable author statement /// 0019747 // regulation of isoprenoid metabolic process // traceable author statement /// 0030301 // cholesterol transport // inferred from direct assay /// 0032366 // intracellular sterol transport // inferred from direct assay /// 0032367 // intracellular cholesterol transport // inferred from direct assay /// 0032367 // intracellular cholesterol transport // inferred from genetic interaction /// 0033344 // cholesterol efflux // inferred from direct assay /// 0042632 // cholesterol homeostasis // inferred from direct assay /// 0046836 // glycolipid transport // traceable author statement","0005576 // extracellular region // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005515 // protein binding // inferred from physical interaction /// 0015485 // cholesterol binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction","---","IPR003172 // MD-2-related lipid-recognition domain // 2.2E-31 /// IPR003172 // MD-2-related lipid-recognition domain // 3.9E-42 /// IPR003172 // MD-2-related lipid-recognition domain // 9.4E-42 /// IPR003172 // MD-2-related lipid-recognition domain // 1.3E-41 /// IPR003172 // MD-2-related lipid-recognition domain // 4.8E-39 /// IPR003172 // MD-2-related lipid-recognition domain // 6.3E-42"
"200832_s_at",1.793465697,1.511351102,1.419901977,"UP","AB032261","chr10:102106880-102124591 (+) // 93.17 // q24.31","stearoyl-CoA desaturase (delta-9-desaturase)","SCD","ENSG00000099194 /// OTTHUMG00000018906","6319","604031","NP_005054","NM_005063","0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation","0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0004768 // stearoyl-CoA 9-desaturase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016717 // oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water // inferred from electronic annotation","Fatty_Acid_Synthesis // GenMAPP","IPR005804 // Fatty acid desaturase, type 1 // 3.4E-15"
"201416_at",1.441497024,1.009564732,1.614667271,"UP","BG528420","chr6:21592999-21598850 (+) // 89.99 // p22.3","SRY (sex determining region Y)-box 4","SOX4","ENSG00000124766 /// OTTHUMG00000016101","6659","184430","NP_003098","NM_003107","0001501 // skeletal system development // inferred from sequence or structural similarity /// 0001841 // neural tube formation // inferred from sequence or structural similarity /// 0002328 // pro-B cell differentiation // inferred from sequence or structural similarity /// 0003183 // mitral valve morphogenesis // inferred from sequence or structural similarity /// 0003211 // cardiac ventricle formation // inferred from sequence or structural similarity /// 0003215 // cardiac right ventricle morphogenesis // inferred from sequence or structural similarity /// 0003289 // atrial septum primum morphogenesis // inferred from sequence or structural similarity /// 0003357 // noradrenergic neuron differentiation // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from mutant phenotype /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0014009 // glial cell proliferation // inferred from sequence or structural similarity /// 0021510 // spinal cord development // inferred from sequence or structural similarity /// 0021522 // spinal cord motor neuron differentiation // inferred from sequence or structural similarity /// 0021782 // glial cell development // inferred from sequence or structural similarity /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030217 // T cell differentiation // inferred from sequence or structural similarity /// 0031018 // endocrine pancreas development // inferred from electronic annotation /// 0031397 // negative regulation of protein ubiquitination // inferred from mutant phenotype /// 0031647 // regulation of protein stability // inferred from mutant phenotype /// 0032024 // positive regulation of insulin secretion // inferred from sequence or structural similarity /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035910 // ascending aorta morphogenesis // inferred from sequence or structural similarity /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0042769 // DNA damage response, detection of DNA damage // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0045727 // positive regulation of translation // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046826 // negative regulation of protein export from nucleus // inferred from mutant phenotype /// 0048485 // sympathetic nervous system development // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from sequence or structural similarity /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0060548 // negative regulation of cell death // inferred from sequence or structural similarity /// 0060563 // neuroepithelial cell differentiation // inferred from sequence or structural similarity /// 0060993 // kidney morphogenesis // inferred from sequence or structural similarity /// 0071333 // cellular response to glucose stimulus // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity /// 2000761 // positive regulation of N-terminal peptidyl-lysine acetylation // inferred from direct assay","0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay","0000976 // transcription regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0001046 // core promoter sequence-specific DNA binding // inferred from direct assay /// 0001071 // nucleic acid binding transcription factor activity // inferred from mutant phenotype /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction","---","IPR009071 // High mobility group box domain // 4.3E-29"
"201465_s_at",-1.231176249,-1.025011264,-1.593885165,"DOWN","BC002646","chr1:59247716-59249688 (-) // 98.5 // p32.1","jun proto-oncogene","JUN","ENSG00000177606 /// OTTHUMG00000008376","3725","165160","NP_002219","NM_002228","0001525 // angiogenesis // inferred from electronic annotation /// 0001774 // microglial cell activation // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007184 // SMAD protein import into nucleus // inferred from direct assay /// 0007568 // aging // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030224 // monocyte differentiation // inferred from electronic annotation /// 0031103 // axon regeneration // inferred from electronic annotation /// 0031953 // negative regulation of protein autophosphorylation // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035026 // leading edge cell differentiation // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0043923 // positive regulation by host of viral transcription // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045657 // positive regulation of monocyte differentiation // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred by curator /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051365 // cellular response to potassium ion starvation // inferred from electronic annotation /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051899 // membrane depolarization // inferred from electronic annotation /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0071277 // cellular response to calcium ion // inferred from electronic annotation","0000228 // nuclear chromosome // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from electronic annotation","0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred by curator /// 0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred by curator /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005100 // Rho GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0035497 // cAMP response element binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070412 // R-SMAD binding // inferred from physical interaction /// 0071837 // HMG box domain binding // inferred from electronic annotation","Apoptosis // GenMAPP /// Apoptosis_GenMAPP // GenMAPP /// MAPK_Cascade // GenMAPP /// Smooth_muscle_contraction // GenMAPP /// TGF_Beta_Signaling_Pathway // GenMAPP /// Wnt_signaling // GenMAPP","IPR004827 // Basic-leucine zipper domain // 4.7E-23 /// IPR004827 // Basic-leucine zipper domain // 1.2E-12 /// IPR005643 // Jun-like transcription factor // 2.3E-89"
"201466_s_at",-1.425721109,-1.15020778,-1.600337783,"DOWN","NM_002228","chr1:59246461-59249715 (-) // 99.05 // p32.1","jun proto-oncogene","JUN","ENSG00000177606 /// OTTHUMG00000008376","3725","165160","NP_002219","NM_002228","0001525 // angiogenesis // inferred from electronic annotation /// 0001774 // microglial cell activation // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0003151 // outflow tract morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007184 // SMAD protein import into nucleus // inferred from direct assay /// 0007568 // aging // inferred from electronic annotation /// 0007612 // learning // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030224 // monocyte differentiation // inferred from electronic annotation /// 0031103 // axon regeneration // inferred from electronic annotation /// 0031953 // negative regulation of protein autophosphorylation // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035026 // leading edge cell differentiation // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0043923 // positive regulation by host of viral transcription // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0045657 // positive regulation of monocyte differentiation // inferred from electronic annotation /// 0045740 // positive regulation of DNA replication // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred by curator /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051365 // cellular response to potassium ion starvation // inferred from electronic annotation /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051899 // membrane depolarization // inferred from electronic annotation /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0071277 // cellular response to calcium ion // inferred from electronic annotation","0000228 // nuclear chromosome // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from electronic annotation","0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0001190 // RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription // inferred by curator /// 0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred by curator /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005100 // Rho GTPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0035497 // cAMP response element binding // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0070412 // R-SMAD binding // inferred from physical interaction /// 0071837 // HMG box domain binding // inferred from electronic annotation","Apoptosis // GenMAPP /// Apoptosis_GenMAPP // GenMAPP /// MAPK_Cascade // GenMAPP /// Smooth_muscle_contraction // GenMAPP /// TGF_Beta_Signaling_Pathway // GenMAPP /// Wnt_signaling // GenMAPP","IPR004827 // Basic-leucine zipper domain // 4.7E-23 /// IPR004827 // Basic-leucine zipper domain // 1.2E-12 /// IPR005643 // Jun-like transcription factor // 2.3E-89"
"201474_s_at",1.021031848,1.064966815,1.193472959,"UP","NM_002204","chr17:48133730-48167844 (+) // 98.79 // q21.33","integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)","ITGA3","---","3675","605025 /// 614748","NP_002195 /// NP_005492 /// XP_005257365","NM_002204 /// NM_005501 /// XM_005257308","0001764 // neuron migration // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010634 // positive regulation of epithelial cell migration // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0031345 // negative regulation of cell projection organization // inferred from electronic annotation /// 0034698 // response to gonadotropin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement /// 0060135 // maternal process involved in female pregnancy // inferred from electronic annotation","0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0008305 // integrin complex // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0034667 // integrin alpha3-beta1 complex // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045202 // synapse // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0001968 // fibronectin binding // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0043236 // laminin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation","Integrin-mediated_cell_adhesion_KEGG // GenMAPP","---"
"201487_at",1.798894376,1.560727893,1.972210705,"UP","NM_001814","chr11:88026760-88070873 (-) // 98.37 // q14.2","cathepsin C","CTSC","ENSG00000109861 /// OTTHUMG00000167290","1075","170650 /// 245000 /// 245010 /// 602365","NP_001107645 /// NP_001805 /// NP_680475","NM_001114173 /// NM_001814 /// NM_148170","0001913 // T cell mediated cytotoxicity // inferred from electronic annotation /// 0006508 // proteolysis // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 1903052 // positive regulation of proteolysis involved in cellular protein catabolic process // inferred from sequence or structural similarity /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation","0005615 // extracellular space // inferred from direct assay /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005764 // lysosome // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from direct assay /// 0016505 // peptidase activator activity involved in apoptotic process // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from sequence or structural similarity /// 0031404 // chloride ion binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0043621 // protein self-association // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from sequence or structural similarity","---","IPR000668 // Peptidase C1A, papain C-terminal // 1.9E-66 /// IPR014882 // Cathepsin C exclusion // 8.6E-61"
"201506_at",1.854538264,1.355934872,1.267135554,"UP","NM_000358","chr5:135364697-135399507 (+) // 99.96 // q31.1","transforming growth factor, beta-induced, 68kDa","TGFBI","ENSG00000120708 /// OTTHUMG00000163213","7045","121820 /// 121900 /// 122200 /// 601692 /// 602082 /// 607541 /// 608470 /// 608471","NP_000349","NM_000358","0001525 // angiogenesis // inferred from expression pattern /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation","0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005178 // integrin binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from physical interaction /// 0050840 // extracellular matrix binding // inferred from electronic annotation","---","IPR000782 // FAS1 domain // 1.5E-29 /// IPR000782 // FAS1 domain // 1.3E-32 /// IPR000782 // FAS1 domain // 8.2E-18 /// IPR000782 // FAS1 domain // 8.9E-34 /// IPR000782 // FAS1 domain // 5.9E-21 /// IPR000782 // FAS1 domain // 2.8E-18 /// IPR000782 // FAS1 domain // 2.9E-34"
"201540_at",-1.374408994,-1.544282451,-1.70769157,"DOWN","NM_001449","chrX:135252084-135293511 (+) // 97.87 // q26.3","four and a half LIM domains 1","FHL1","ENSG00000022267 /// OTTHUMG00000022504","2273","300163 /// 300695 /// 300696 /// 300717 /// 300718","NP_001153171 /// NP_001153172 /// NP_001153173 /// NP_001153174 /// NP_001153175 /// NP_001153176 /// NP_001161291 /// NP_001440 /// XP_006724806 /// XP_006724807 /// XP_006724808 /// XP_006724809 /// XP_006724810","NM_001159699 /// NM_001159700 /// NM_001159701 /// NM_001159702 /// NM_001159703 /// NM_001159704 /// NM_001167819 /// NM_001449 /// NR_027621 /// XM_006724743 /// XM_006724744 /// XM_006724745 /// XM_006724746 /// XM_006724747","0003254 // regulation of membrane depolarization // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // non-traceable author statement /// 0009887 // organ morphogenesis // non-traceable author statement /// 0010972 // negative regulation of G2/M transition of mitotic cell cycle // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 1901016 // regulation of potassium ion transmembrane transporter activity // inferred from direct assay /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from direct assay","0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay","0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR001781 // Zinc finger, LIM-type // 5.2E-15 /// IPR001781 // Zinc finger, LIM-type // 6.4E-16 /// IPR001781 // Zinc finger, LIM-type // 9.6E-16 /// IPR001781 // Zinc finger, LIM-type // 5.2E-14 /// IPR001781 // Zinc finger, LIM-type // 6.6E-15 /// IPR001781 // Zinc finger, LIM-type // 8.1E-16 /// IPR001781 // Zinc finger, LIM-type // 1.2E-15 /// IPR001781 // Zinc finger, LIM-type // 5.7E-15 /// IPR001781 // Zinc finger, LIM-type // 7.1E-16 /// IPR001781 // Zinc finger, LIM-type // 1.0E-15 /// IPR001781 // Zinc finger, LIM-type // 5.7E-14 /// IPR001781 // Zinc finger, LIM-type // 6.1E-15 /// IPR001781 // Zinc finger, LIM-type // 7.6E-16 /// IPR001781 // Zinc finger, LIM-type // 1.1E-15 /// IPR001781 // Zinc finger, LIM-type // 6.1E-14"
"201645_at",3.068746816,2.164484755,1.477747534,"UP","NM_002160","chr9:117782812-117880439 (-) // 99.26 // q33.1","tenascin C","TNC","ENSG00000041982 /// OTTHUMG00000021010","3371","187380 /// 615629","NP_002151 /// XP_005252029 /// XP_005252030 /// XP_005252031 /// XP_005252032 /// XP_006717159 /// XP_006717160 /// XP_006717161 /// XP_006717162 /// XP_006717163 /// XP_006717164","NM_002160 /// XM_005251972 /// XM_005251973 /// XM_005251974 /// XM_005251975 /// XM_006717096 /// XM_006717097 /// XM_006717098 /// XM_006717099 /// XM_006717100 /// XM_006717101","0001649 // osteoblast differentiation // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // inferred from electronic annotation /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009611 // response to wounding // inferred from expression pattern /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0014012 // peripheral nervous system axon regeneration // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0031175 // neuron projection development // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0060447 // bud outgrowth involved in lung branching // inferred from electronic annotation /// 0060739 // mesenchymal-epithelial cell signaling involved in prostate gland development // inferred from electronic annotation /// 0060740 // prostate gland epithelium morphogenesis // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0071305 // cellular response to vitamin D // inferred from electronic annotation /// 0071774 // response to fibroblast growth factor // inferred from electronic annotation /// 0071799 // cellular response to prostaglandin D stimulus // inferred from electronic annotation","0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005614 // interstitial matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity","0005515 // protein binding // inferred from electronic annotation /// 0045545 // syndecan binding // inferred from physical interaction","---","IPR002181 // Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain // 3.2E-85 /// IPR002181 // Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain // 3.5E-85 /// IPR002181 // Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain // 2.3E-85 /// IPR003961 // Fibronectin, type III // 3.4E-14 /// IPR003961 // Fibronectin, type III // 1.0E-17 /// IPR003961 // Fibronectin, type III // 7.1E-14 /// IPR003961 // Fibronectin, type III // 8.0E-19 /// IPR003961 // Fibronectin, type III // 2.3E-17 /// IPR003961 // Fibronectin, type III // 1.2E-14 /// IPR003961 // Fibronectin, type III // 8.4E-14 /// IPR003961 // Fibronectin, type III // 1.3E-16 /// IPR003961 // Fibronectin, type III // 5.2E-13 /// IPR003961 // Fibronectin, type III // 4.5E-11 /// IPR003961 // Fibronectin, type III // 1.1E-11 /// IPR003961 // Fibronectin, type III // 2.4E-12 /// IPR003961 // Fibronectin, type III // 6.0E-16 /// IPR003961 // Fibronectin, type III // 2.4E-13 /// IPR003961 // Fibronectin, type III // 1.5E-18 /// IPR003961 // Fibronectin, type III // 3.9E-14 /// IPR003961 // Fibronectin, type III // 1.2E-17 /// IPR003961 // Fibronectin, type III // 8.1E-14 /// IPR003961 // Fibronectin, type III // 9.1E-19 /// IPR003961 // Fibronectin, type III // 2.6E-17 /// IPR003961 // Fibronectin, type III // 1.4E-14 /// IPR003961 // Fibronectin, type III // 9.5E-14 /// IPR003961 // Fibronectin, type III // 5.9E-13 /// IPR003961 // Fibronectin, type III // 5.1E-11 /// IPR003961 // Fibronectin, type III // 2.8E-12 /// IPR003961 // Fibronectin, type III // 6.8E-16 /// IPR003961 // Fibronectin, type III // 2.7E-13 /// IPR003961 // Fibronectin, type III // 1.7E-18 /// IPR003961 // Fibronectin, type III // 2.6E-14 /// IPR003961 // Fibronectin, type III // 8.0E-18 /// IPR003961 // Fibronectin, type III // 5.5E-14 /// IPR003961 // Fibronectin, type III // 6.1E-19 /// IPR003961 // Fibronectin, type III // 1.8E-17 /// IPR003961 // Fibronectin, type III // 3.5E-11 /// IPR003961 // Fibronectin, type III // 1.9E-12 /// IPR003961 // Fibronectin, type III // 4.6E-16 /// IPR003961 // Fibronectin, type III // 1.8E-13 /// IPR003961 // Fibronectin, type III // 1.2E-18 /// IPR013111 // EGF-like domain, extracellular // 3.8E-7 /// IPR013111 // EGF-like domain, extracellular // 2.6E-8 /// IPR013111 // EGF-like domain, extracellular // 3.8E-8 /// IPR013111 // EGF-like domain, extracellular // 2.8E-6 /// IPR013111 // EGF-like domain, extracellular // 7.2E-7 /// IPR013111 // EGF-like domain, extracellular // 2.7E-6 /// IPR013111 // EGF-like domain, extracellular // 1.8E-9 /// IPR013111 // EGF-like domain, extracellular // 1.5E-8 /// IPR013111 // EGF-like domain, extracellular // 8.4E-7 /// IPR013111 // EGF-like domain, extracellular // 9.7E-9 /// IPR013111 // EGF-like domain, extracellular // 8.9E-9 /// IPR013111 // EGF-like domain, extracellular // 1.1E-8 /// IPR013111 // EGF-like domain, extracellular // 9.6E-8 /// IPR013111 // EGF-like domain, extracellular // 2.1E-7 /// IPR013111 // EGF-like domain, extracellular // 4.3E-7 /// IPR013111 // EGF-like domain, extracellular // 3.0E-8 /// IPR013111 // EGF-like domain, extracellular // 4.3E-8 /// IPR013111 // EGF-like domain, extracellular // 3.2E-6 /// IPR013111 // EGF-like domain, extracellular // 8.1E-7 /// IPR013111 // EGF-like domain, extracellular // 3.1E-6 /// IPR013111 // EGF-like domain, extracellular // 2.0E-9 /// IPR013111 // EGF-like domain, extracellular // 1.8E-8 /// IPR013111 // EGF-like domain, extracellular // 9.6E-7 /// IPR013111 // EGF-like domain, extracellular // 1.1E-8 /// IPR013111 // EGF-like domain, extracellular // 1.0E-8 /// IPR013111 // EGF-like domain, extracellular // 1.2E-8 /// IPR013111 // EGF-like domain, extracellular // 1.1E-7 /// IPR013111 // EGF-like domain, extracellular // 2.4E-7 /// IPR013111 // EGF-like domain, extracellular // 3.0E-7 /// IPR013111 // EGF-like domain, extracellular // 2.0E-8 /// IPR013111 // EGF-like domain, extracellular // 3.0E-8 /// IPR013111 // EGF-like domain, extracellular // 2.2E-6 /// IPR013111 // EGF-like domain, extracellular // 5.6E-7 /// IPR013111 // EGF-like domain, extracellular // 2.1E-6 /// IPR013111 // EGF-like domain, extracellular // 1.4E-9 /// IPR013111 // EGF-like domain, extracellular // 1.2E-8 /// IPR013111 // EGF-like domain, extracellular // 6.6E-7 /// IPR013111 // EGF-like domain, extracellular // 7.5E-9 /// IPR013111 // EGF-like domain, extracellular // 6.9E-9 /// IPR013111 // EGF-like domain, extracellular // 8.3E-9 /// IPR013111 // EGF-like domain, extracellular // 7.4E-8 /// IPR013111 // EGF-like domain, extracellular // 1.7E-7"
"201650_at",1.718890351,2.59745563,1.947014491,"UP","NM_002276","chr17:39679869-39684528 (-) // 99.41 // q21.2","keratin 19","KRT19","ENSG00000171345 /// OTTHUMG00000133422","3880","148020","NP_002267","NM_002276","0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from expression pattern /// 0045214 // sarcomere organization // inferred from direct assay /// 0060706 // cell differentiation involved in embryonic placenta development // inferred from electronic annotation","0005882 // intermediate filament // inferred from electronic annotation /// 0016010 // dystrophin-associated glycoprotein complex // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043034 // costamere // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from direct assay","0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008307 // structural constituent of muscle // inferred from direct assay /// 0032403 // protein complex binding // inferred from electronic annotation","---","IPR001664 // Intermediate filament protein // 2.0E-123"
"201666_at",2.270887621,2.332940562,1.757675218,"UP","NM_003254","chrX:47441830-47446187 (+) // 98.21 // p11.23","TIMP metallopeptidase inhibitor 1","TIMP1","ENSG00000102265 /// OTTHUMG00000021447","7076","305370","NP_003245 /// XP_005272702","NM_003254 /// XM_005272645","0001775 // cell activation // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043249 // erythrocyte maturation // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0048553 // negative regulation of metalloenzyme activity // inferred from direct assay /// 0051045 // negative regulation of membrane protein ectodomain proteolysis // inferred from direct assay /// 1901164 // negative regulation of trophoblast cell migration // inferred from mutant phenotype /// 2001044 // regulation of integrin-mediated signaling pathway // inferred from mutant phenotype","0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0002020 // protease binding // inferred from electronic annotation /// 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005125 // cytokine activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008191 // metalloendopeptidase inhibitor activity // inferred from direct assay /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","MAPK_Cascade // GenMAPP /// Matrix_Metalloproteinases // GenMAPP","IPR001820 // Proteinase inhibitor I35, tissue inhibitor of metalloproteinase // 2.4E-65 /// IPR001820 // Proteinase inhibitor I35, tissue inhibitor of metalloproteinase // 2.6E-47"
"201842_s_at",-1.771260824,-1.412007774,-1.458228042,"DOWN","AI826799","chr2:56093101-56150917 (-) // 97.28 // p16.1","EGF containing fibulin-like extracellular matrix protein 1","EFEMP1","ENSG00000115380 /// OTTHUMG00000129343","2202","126600 /// 601548","NP_001034437 /// NP_001034438 /// XP_005264262","NM_001039348 /// NM_001039349 /// NM_004105 /// XM_005264205","0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0007601 // visual perception // traceable author statement /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0032331 // negative regulation of chondrocyte differentiation // inferred from direct assay","0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005006 // epidermal growth factor-activated receptor activity // inferred from direct assay /// 0005154 // epidermal growth factor receptor binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation","---","IPR001881 // EGF-like calcium-binding domain // 5.7E-11 /// IPR001881 // EGF-like calcium-binding domain // 1.8E-17 /// IPR001881 // EGF-like calcium-binding domain // 1.9E-12 /// IPR001881 // EGF-like calcium-binding domain // 6.4E-11 /// IPR001881 // EGF-like calcium-binding domain // 2.7E-11 /// IPR001881 // EGF-like calcium-binding domain // 1.5E-9"
"201843_s_at",-1.986507609,-1.410675665,-1.89762582,"DOWN","NM_004105","chr2:56093097-56150178 (-) // 98.29 // p16.1","EGF containing fibulin-like extracellular matrix protein 1","EFEMP1","ENSG00000115380 /// OTTHUMG00000129343","2202","126600 /// 601548","NP_001034437 /// NP_001034438 /// XP_005264262","NM_001039348 /// NM_001039349 /// NM_004105 /// XM_005264205","0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from direct assay /// 0007601 // visual perception // traceable author statement /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0032331 // negative regulation of chondrocyte differentiation // inferred from direct assay","0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005006 // epidermal growth factor-activated receptor activity // inferred from direct assay /// 0005154 // epidermal growth factor receptor binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation","---","IPR001881 // EGF-like calcium-binding domain // 5.7E-11 /// IPR001881 // EGF-like calcium-binding domain // 1.8E-17 /// IPR001881 // EGF-like calcium-binding domain // 1.9E-12 /// IPR001881 // EGF-like calcium-binding domain // 6.4E-11 /// IPR001881 // EGF-like calcium-binding domain // 2.7E-11 /// IPR001881 // EGF-like calcium-binding domain // 1.5E-9"
"201925_s_at",1.03418463,1.591495944,1.571014368,"UP","NM_000574","chr1:207495045-207533846 (+) // 98.86 // q32.2","CD55 molecule, decay accelerating factor for complement (Cromer blood group)","CD55","ENSG00000196352 /// OTTHUMG00000036255","1604","125240 /// 613793","NP_000565 /// NP_001108224 /// XP_005273134","NM_000574 /// NM_001114543 /// NM_001114544 /// NM_001114752 /// XM_005273077","0002376 // immune system process // inferred from electronic annotation /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0009615 // response to virus // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0031664 // regulation of lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0035743 // CD4-positive, alpha-beta T cell cytokine production // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045730 // respiratory burst // non-traceable author statement /// 0045916 // negative regulation of complement activation // inferred from direct assay /// 0060137 // maternal process involved in parturition // inferred from electronic annotation /// 2000516 // positive regulation of CD4-positive, alpha-beta T cell activation // inferred from direct assay /// 2000563 // positive regulation of CD4-positive, alpha-beta T cell proliferation // inferred from direct assay","0005576 // extracellular region // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0001618 // virus receptor activity // inferred from direct assay /// 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from direct assay","Complement_Activation_Classical // GenMAPP","IPR000436 // Sushi/SCR/CCP // 7.9E-11 /// IPR000436 // Sushi/SCR/CCP // 4.1E-15 /// IPR000436 // Sushi/SCR/CCP // 9.8E-13 /// IPR000436 // Sushi/SCR/CCP // 1.0E-16 /// IPR000436 // Sushi/SCR/CCP // 6.0E-11 /// IPR000436 // Sushi/SCR/CCP // 7.4E-13 /// IPR000436 // Sushi/SCR/CCP // 7.5E-17 /// IPR000436 // Sushi/SCR/CCP // 9.7E-11 /// IPR000436 // Sushi/SCR/CCP // 5.0E-15 /// IPR000436 // Sushi/SCR/CCP // 1.2E-12 /// IPR000436 // Sushi/SCR/CCP // 1.2E-16"
"201926_s_at",1.123470459,1.643395152,1.594599327,"UP","BC001288","chr1:207495031-207533057 (+) // 97.79 // q32.2","CD55 molecule, decay accelerating factor for complement (Cromer blood group)","CD55","ENSG00000196352 /// OTTHUMG00000036255","1604","125240 /// 613793","NP_000565 /// NP_001108224 /// XP_005273134","NM_000574 /// NM_001114543 /// NM_001114544 /// NM_001114752 /// XM_005273077","0002376 // immune system process // inferred from electronic annotation /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0009615 // response to virus // inferred from direct assay /// 0009615 // response to virus // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0031664 // regulation of lipopolysaccharide-mediated signaling pathway // inferred from direct assay /// 0035743 // CD4-positive, alpha-beta T cell cytokine production // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045730 // respiratory burst // non-traceable author statement /// 0045916 // negative regulation of complement activation // inferred from direct assay /// 0060137 // maternal process involved in parturition // inferred from electronic annotation /// 2000516 // positive regulation of CD4-positive, alpha-beta T cell activation // inferred from direct assay /// 2000563 // positive regulation of CD4-positive, alpha-beta T cell proliferation // inferred from direct assay","0005576 // extracellular region // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0001618 // virus receptor activity // inferred from direct assay /// 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from direct assay","Complement_Activation_Classical // GenMAPP","IPR000436 // Sushi/SCR/CCP // 7.9E-11 /// IPR000436 // Sushi/SCR/CCP // 4.1E-15 /// IPR000436 // Sushi/SCR/CCP // 9.8E-13 /// IPR000436 // Sushi/SCR/CCP // 1.0E-16 /// IPR000436 // Sushi/SCR/CCP // 6.0E-11 /// IPR000436 // Sushi/SCR/CCP // 7.4E-13 /// IPR000436 // Sushi/SCR/CCP // 7.5E-17 /// IPR000436 // Sushi/SCR/CCP // 9.7E-11 /// IPR000436 // Sushi/SCR/CCP // 5.0E-15 /// IPR000436 // Sushi/SCR/CCP // 1.2E-12 /// IPR000436 // Sushi/SCR/CCP // 1.2E-16 /// IPR000436 // Sushi/SCR/CCP // 1.1E-11"
"202071_at",1.941099341,1.968481919,1.600349397,"UP","NM_002999","chr20:43953930-43977050 (-) // 90.82 // q13.12","syndecan 4","SDC4","ENSG00000124145 /// OTTHUMG00000033083","6385","600017","NP_002990","NM_002999","0001523 // retinoid metabolic process // traceable author statement /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006024 // glycosaminoglycan biosynthetic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from electronic annotation /// 0051894 // positive regulation of focal adhesion assembly // inferred from electronic annotation","0005576 // extracellular region // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043034 // costamere // inferred from electronic annotation /// 0043202 // lysosomal lumen // traceable author statement /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0001968 // fibronectin binding // inferred from electronic annotation /// 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0070053 // thrombospondin receptor activity // inferred from mutant phenotype","---","IPR027789 // Syndecan/Neurexin domain // 1.1E-34"
"202267_at",1.031031533,1.184257048,1.222657694,"UP","NM_005562","chr1:183155398-183214039 (+) // 96.35 // q25.3","laminin, gamma 2","LAMC2","ENSG00000058085 /// OTTHUMG00000035520","3918","150292 /// 226650 /// 226700","NP_005553 /// NP_061486 /// XP_005245207 /// XP_006711379","NM_005562 /// NM_018891 /// XM_005245150 /// XM_006711316","0007155 // cell adhesion // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0031581 // hemidesmosome assembly // traceable author statement /// 0034329 // cell junction assembly // traceable author statement","0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005607 // laminin-2 complex // inferred from electronic annotation /// 0005610 // laminin-5 complex // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation","0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation","Inflammatory_Response_Pathway // GenMAPP","IPR000034 // Laminin B type IV // 3.5E-32 /// IPR002049 // EGF-like, laminin // 1.3E-8 /// IPR002049 // EGF-like, laminin // 8.0E-14 /// IPR002049 // EGF-like, laminin // 3.9E-12 /// IPR002049 // EGF-like, laminin // 4.8E-6 /// IPR002049 // EGF-like, laminin // 2.8E-8 /// IPR002049 // EGF-like, laminin // 1.2E-13 /// IPR002049 // EGF-like, laminin // 5.6E-7"
"202286_s_at",2.852880361,3.562678783,3.213541991,"UP","J04152","chr1:59040642-59043445 (-) // 93.63 // p32.1","tumor-associated calcium signal transducer 2","TACSTD2","ENSG00000184292 /// OTTHUMG00000010067","4070","137290 /// 204870","NP_002344","NM_002353","0000320 // re-entry into mitotic cell cycle // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007595 // lactation // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010633 // negative regulation of epithelial cell migration // inferred from sequence or structural similarity /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030857 // negative regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032026 // response to magnesium ion // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0033598 // mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0033601 // positive regulation of mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051497 // negative regulation of stress fiber assembly // inferred from sequence or structural similarity /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060675 // ureteric bud morphogenesis // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0090191 // negative regulation of branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 1900025 // negative regulation of substrate adhesion-dependent cell spreading // inferred from sequence or structural similarity /// 1900028 // negative regulation of ruffle assembly // inferred from sequence or structural similarity /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 2000146 // negative regulation of cell motility // inferred from sequence or structural similarity /// 2000738 // positive regulation of stem cell differentiation // inferred from electronic annotation","0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005923 // tight junction // inferred from electronic annotation /// 0009925 // basal plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0004672 // protein kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016538 // cyclin-dependent protein serine/threonine kinase regulator activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation","---","IPR000716 // Thyroglobulin type-1 // 2.7E-20"
"202295_s_at",1.443915631,1.999971133,1.924833099,"UP","NM_004390","chr15:79214115-79237351 (-) // 99.14 // q25.1","cathepsin H","CTSH","ENSG00000103811 /// OTTHUMG00000144171","1512","116820","NP_004381 /// XP_005254238","NM_004390 /// NM_148979 /// XM_005254181","0001656 // metanephros development // inferred from sequence or structural similarity /// 0001913 // T cell mediated cytotoxicity // inferred from sequence or structural similarity /// 0002250 // adaptive immune response // inferred from expression pattern /// 0002764 // immune response-regulating signaling pathway // inferred from direct assay /// 0006508 // proteolysis // inferred from direct assay /// 0006508 // proteolysis // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010634 // positive regulation of epithelial cell migration // inferred from sequence or structural similarity /// 0010813 // neuropeptide catabolic process // inferred from direct assay /// 0010815 // bradykinin catabolic process // inferred from direct assay /// 0010952 // positive regulation of peptidase activity // inferred from direct assay /// 0019882 // antigen processing and presentation // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0031638 // zymogen activation // inferred from direct assay /// 0031648 // protein destabilization // inferred from mutant phenotype /// 0032526 // response to retinoic acid // inferred from sequence or structural similarity /// 0033619 // membrane protein proteolysis // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043129 // surfactant homeostasis // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0060448 // dichotomous subdivision of terminal units involved in lung branching // inferred from sequence or structural similarity /// 0070371 // ERK1 and ERK2 cascade // inferred from direct assay /// 0097067 // cellular response to thyroid hormone stimulus // inferred from expression pattern /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation","0001520 // outer dense fiber // inferred from electronic annotation /// 0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0097208 // alveolar lamellar body // inferred from direct assay","0004175 // endopeptidase activity // inferred from direct assay /// 0004177 // aminopeptidase activity // inferred from direct assay /// 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004252 // serine-type endopeptidase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // inferred from direct assay /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // inferred from direct assay /// 0016505 // peptidase activator activity involved in apoptotic process // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030108 // HLA-A specific activating MHC class I receptor activity // inferred from direct assay /// 0030984 // kininogen binding // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation /// 0043621 // protein self-association // inferred from electronic annotation /// 0070324 // thyroid hormone binding // inferred from direct assay","---","IPR000668 // Peptidase C1A, papain C-terminal // 5.4E-83 /// IPR013201 // Proteinase inhibitor I29, cathepsin propeptide // 4.8E-22"
"202311_s_at",2.277669018,1.752146223,1.645588867,"UP","AI743621","chr17:48260649-48278993 (-) // 97.0 // q21.33","collagen, type I, alpha 1","COL1A1","ENSG00000108821 /// OTTHUMG00000148674","1277","114000 /// 120150 /// 130000 /// 130060 /// 166200 /// 166210 /// 166220 /// 166710 /// 259420","NP_000079 /// XP_005257115 /// XP_005257116 /// XP_006721766","NM_000088 /// XM_005257058 /// XM_005257059 /// XM_006721703","0001501 // skeletal system development // inferred from mutant phenotype /// 0001503 // ossification // inferred from electronic annotation /// 0001568 // blood vessel development // inferred from mutant phenotype /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001957 // intramembranous ossification // inferred from electronic annotation /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007601 // visual perception // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010812 // negative regulation of cell-substrate adhesion // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030574 // collagen catabolic process // traceable author statement /// 0031960 // response to corticosteroid // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032964 // collagen biosynthetic process // inferred from mutant phenotype /// 0034504 // protein localization to nucleus // inferred from direct assay /// 0034505 // tooth mineralization // inferred from mutant phenotype /// 0042060 // wound healing // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0043589 // skin morphogenesis // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048706 // embryonic skeletal system development // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0051591 // response to cAMP // inferred from electronic annotation /// 0060325 // face morphogenesis // inferred from electronic annotation /// 0060346 // bone trabecula formation // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation /// 0070208 // protein heterotrimerization // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from direct assay","0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005584 // collagen type I trimer // inferred from mutant phenotype /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity","0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048407 // platelet-derived growth factor binding // inferred from direct assay","Inflammatory_Response_Pathway // GenMAPP","IPR000885 // Fibrillar collagen, C-terminal // 7.3E-101 /// IPR001007 // von Willebrand factor, type C // 2.5E-15 /// IPR008160 // Collagen triple helix repeat // 1.6E-11 /// IPR008160 // Collagen triple helix repeat // 4.4E-13 /// IPR008160 // Collagen triple helix repeat // 1.6E-15 /// IPR008160 // Collagen triple helix repeat // 2.8E-14 /// IPR008160 // Collagen triple helix repeat // 2.8E-13 /// IPR008160 // Collagen triple helix repeat // 3.1E-12 /// IPR008160 // Collagen triple helix repeat // 1.6E-13 /// IPR008160 // Collagen triple helix repeat // 1.0E-11 /// IPR008160 // Collagen triple helix repeat // 1.6E-10 /// IPR008160 // Collagen triple helix repeat // 1.4E-14 /// IPR008160 // Collagen triple helix repeat // 1.8E-12 /// IPR008160 // Collagen triple helix repeat // 4.1E-14 /// IPR008160 // Collagen triple helix repeat // 7.6E-12"
"202350_s_at",-2.84284884,-1.912770131,-2.343431484,"DOWN","NM_002380","chr8:98900204-99048440 (+) // 99.83 // q22.1","uncharacterized LOC100506558 /// matrilin 2","LOC100506558 /// MATN2","ENSG00000132561 /// OTTHUMG00000164795","4147 /// 100506558","602108","NP_002371 /// NP_085072 /// XP_005250977","NM_002380 /// NM_030583 /// XM_005250920 /// XR_108869 /// XR_133494 /// XR_171741","0001764 // neuron migration // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation /// 0008347 // glial cell migration // inferred from electronic annotation /// 0031104 // dendrite regeneration // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from electronic annotation","0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity","0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction","---","IPR000742 // Epidermal growth factor-like domain // 7.9E-9 /// IPR000742 // Epidermal growth factor-like domain // 5.5E-9 /// IPR000742 // Epidermal growth factor-like domain // 8.3E-9 /// IPR000742 // Epidermal growth factor-like domain // 6.0E-9 /// IPR001881 // EGF-like calcium-binding domain // 1.0E-9 /// IPR001881 // EGF-like calcium-binding domain // 2.7E-9 /// IPR001881 // EGF-like calcium-binding domain // 5.7E-10 /// IPR001881 // EGF-like calcium-binding domain // 1.1E-8 /// IPR001881 // EGF-like calcium-binding domain // 2.0E-8 /// IPR001881 // EGF-like calcium-binding domain // 4.0E-10 /// IPR001881 // EGF-like calcium-binding domain // 8.4E-9 /// IPR001881 // EGF-like calcium-binding domain // 7.8E-9 /// IPR001881 // EGF-like calcium-binding domain // 1.1E-9 /// IPR001881 // EGF-like calcium-binding domain // 2.8E-9 /// IPR001881 // EGF-like calcium-binding domain // 6.0E-10 /// IPR001881 // EGF-like calcium-binding domain // 1.3E-8 /// IPR001881 // EGF-like calcium-binding domain // 1.2E-8 /// IPR001881 // EGF-like calcium-binding domain // 7.5E-10 /// IPR001881 // EGF-like calcium-binding domain // 6.0E-10 /// IPR001881 // EGF-like calcium-binding domain // 9.1E-9 /// IPR001881 // EGF-like calcium-binding domain // 8.5E-9 /// IPR002035 // von Willebrand factor, type A // 2.4E-51 /// IPR002035 // von Willebrand factor, type A // 8.1E-53 /// IPR002035 // von Willebrand factor, type A // 4.8E-53 /// IPR002035 // von Willebrand factor, type A // 2.6E-51 /// IPR002035 // von Willebrand factor, type A // 8.7E-53 /// IPR002035 // von Willebrand factor, type A // 4.1E-9 /// IPR002035 // von Willebrand factor, type A // 5.4E-53 /// IPR019466 // Matrilin, coiled-coil trimerisation domain // 5.1E-23 /// IPR019466 // Matrilin, coiled-coil trimerisation domain // 3.5E-23 /// IPR019466 // Matrilin, coiled-coil trimerisation domain // 5.4E-23 /// IPR019466 // Matrilin, coiled-coil trimerisation domain // 3.8E-23 /// IPR019466 // Matrilin, coiled-coil trimerisation domain // 1.0E-20"
"202357_s_at",1.530826707,2.115929689,1.861012536,"UP","NM_001710","chr6:31913958-31919860 (+) // 99.92 // p21.33","complement factor B","CFB","ENSG00000239754 /// ENSG00000241253 /// ENSG00000241534 /// ENSG00000242335 /// ENSG00000243570 /// ENSG00000243649 /// ENSG00000244255 /// OTTHUMG00000004992 /// OTTHUMG00000031198 /// OTTHUMG00000031499 /// OTTHUMG00000137485 /// OTTHUMG00000149098 /// OTTHUMG00000149616 /// OTTHUMG00000159600","629","138470 /// 612924 /// 615489 /// 615561","NP_001701","NM_001710","0002376 // immune system process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006956 // complement activation // traceable author statement /// 0006957 // complement activation, alternative pathway // non-traceable author statement /// 0006957 // complement activation, alternative pathway // traceable author statement /// 0030449 // regulation of complement activation // traceable author statement /// 0045087 // innate immune response // traceable author statement","0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay","0001848 // complement binding // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation","---","IPR000436 // Sushi/SCR/CCP // 5.9E-7 /// IPR000436 // Sushi/SCR/CCP // 4.0E-13 /// IPR000436 // Sushi/SCR/CCP // 2.0E-12 /// IPR000436 // Sushi/SCR/CCP // 2.1E-11 /// IPR000436 // Sushi/SCR/CCP // 1.3E-6 /// IPR000436 // Sushi/SCR/CCP // 9.3E-13 /// IPR000436 // Sushi/SCR/CCP // 4.5E-12 /// IPR000436 // Sushi/SCR/CCP // 1.5E-12 /// IPR000436 // Sushi/SCR/CCP // 8.0E-13 /// IPR000436 // Sushi/SCR/CCP // 3.9E-12 /// IPR001254 // Peptidase S1 // 3.4E-50 /// IPR001254 // Peptidase S1 // 3.1E-50 /// IPR001254 // Peptidase S1 // 9.6E-35 /// IPR001254 // Peptidase S1 // 4.0E-24 /// IPR001254 // Peptidase S1 // 9.9E-50 /// IPR001254 // Peptidase S1 // 1.2E-24 /// IPR001254 // Peptidase S1 // 8.0E-50 /// IPR002035 // von Willebrand factor, type A // 2.2E-44 /// IPR002035 // von Willebrand factor, type A // 3.2E-14 /// IPR002035 // von Willebrand factor, type A // 7.5E-27 /// IPR002035 // von Willebrand factor, type A // 6.5E-44 /// IPR002035 // von Willebrand factor, type A // 3.3E-14 /// IPR002035 // von Willebrand factor, type A // 5.3E-44"
"202363_at",2.031667875,1.081922349,1.065097841,"UP","AF231124","chr5:136310991-136834249 (-) // 99.17 // q31.2","sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1","SPOCK1","ENSG00000152377 /// OTTHUMG00000129157","6695","602264","NP_004589","NM_004598","0001558 // regulation of cell growth // non-traceable author statement /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0007155 // cell adhesion // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // non-traceable author statement /// 0010812 // negative regulation of cell-substrate adhesion // inferred from direct assay /// 0010951 // negative regulation of endopeptidase activity // inferred from direct assay /// 0010977 // negative regulation of neuron projection development // inferred from direct assay /// 0021953 // central nervous system neuron differentiation // inferred from sequence or structural similarity /// 0022008 // neurogenesis // inferred from sequence or structural similarity","0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // non-traceable author statement /// 0016528 // sarcoplasm // inferred from sequence or structural similarity /// 0031594 // neuromuscular junction // inferred from sequence or structural similarity /// 0033268 // node of Ranvier // inferred from sequence or structural similarity","0004867 // serine-type endopeptidase inhibitor activity // non-traceable author statement /// 0004869 // cysteine-type endopeptidase inhibitor activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008191 // metalloendopeptidase inhibitor activity // inferred from direct assay","---","IPR000716 // Thyroglobulin type-1 // 3.9E-20 /// IPR002350 // Kazal domain // 6.6E-13 /// IPR002350 // Kazal domain // 3.2E-10 /// IPR019577 // SPARC/Testican, calcium-binding domain // 4.9E-34"
"202404_s_at",1.805435728,1.373472704,1.618318057,"UP","NM_000089","chr7:94024206-94060544 (+) // 99.08 // q21.3","collagen, type I, alpha 2","COL1A2","ENSG00000164692 /// OTTHUMG00000148675","1278","120160 /// 130060 /// 166210 /// 166220 /// 166710 /// 225320 /// 259420","NP_000080","NM_000089","0001501 // skeletal system development // inferred from mutant phenotype /// 0001568 // blood vessel development // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007266 // Rho protein signal transduction // inferred from direct assay /// 0007596 // blood coagulation // traceable author statement /// 0008217 // regulation of blood pressure // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030574 // collagen catabolic process // traceable author statement /// 0042476 // odontogenesis // non-traceable author statement /// 0043589 // skin morphogenesis // inferred from mutant phenotype /// 0050900 // leukocyte migration // traceable author statement /// 0070208 // protein heterotrimerization // inferred from electronic annotation /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation","0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005584 // collagen type I trimer // inferred from direct assay /// 0005584 // collagen type I trimer // inferred from mutant phenotype /// 0005584 // collagen type I trimer // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from mutant phenotype /// 0042802 // identical protein binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048407 // platelet-derived growth factor binding // inferred from direct assay","---","IPR000885 // Fibrillar collagen, C-terminal // 9.0E-96 /// IPR008160 // Collagen triple helix repeat // 1.4E-11 /// IPR008160 // Collagen triple helix repeat // 8.5E-13 /// IPR008160 // Collagen triple helix repeat // 1.6E-10 /// IPR008160 // Collagen triple helix repeat // 1.4E-11 /// IPR008160 // Collagen triple helix repeat // 9.0E-12 /// IPR008160 // Collagen triple helix repeat // 4.3E-12 /// IPR008160 // Collagen triple helix repeat // 3.3E-9 /// IPR008160 // Collagen triple helix repeat // 2.1E-11"
"202435_s_at",2.682928393,1.396915868,1.962085716,"UP","AU154504","chr2:38294651-38303710 (-) // 98.62 // p22.2","cytochrome P450, family 1, subfamily B, polypeptide 1","CYP1B1","ENSG00000138061 /// OTTHUMG00000100970","1545","231300 /// 600975 /// 601771 /// 604229","NP_000095","NM_000104","0001525 // angiogenesis // inferred from electronic annotation /// 0002930 // trabecular meshwork development // inferred from sequence or structural similarity /// 0006725 // cellular aromatic compound metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006809 // nitric oxide biosynthetic process // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0007601 // visual perception // traceable author statement /// 0008202 // steroid metabolic process // inferred from direct assay /// 0008210 // estrogen metabolic process // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from sequence or structural similarity /// 0009404 // toxin metabolic process // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from sequence or structural similarity /// 0016125 // sterol metabolic process // traceable author statement /// 0019369 // arachidonic acid metabolic process // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // traceable author statement /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0033629 // negative regulation of cell adhesion mediated by integrin // inferred from sequence or structural similarity /// 0042572 // retinol metabolic process // inferred from direct assay /// 0042574 // retinal metabolic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0046427 // positive regulation of JAK-STAT cascade // inferred from sequence or structural similarity /// 0046466 // membrane lipid catabolic process // inferred from sequence or structural similarity /// 0048514 // blood vessel morphogenesis // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // traceable author statement /// 0061298 // retina vasculature development in camera-type eye // inferred from electronic annotation /// 0061304 // retinal blood vessel morphogenesis // inferred from sequence or structural similarity /// 0070301 // cellular response to hydrogen peroxide // inferred from sequence or structural similarity /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay /// 0071603 // endothelial cell-cell adhesion // inferred from electronic annotation /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement /// 1901313 // positive regulation of gene expression involved in extracellular matrix organization // inferred from sequence or structural similarity /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from sequence or structural similarity","0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation","0004497 // monooxygenase activity // inferred from direct assay /// 0004497 // monooxygenase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from direct assay /// 0019825 // oxygen binding // traceable author statement /// 0020037 // heme binding // inferred from direct assay /// 0020037 // heme binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation","---","IPR001128 // Cytochrome P450 // 2.5E-105"
"202436_s_at",2.821843073,2.680215343,2.533085748,"UP","AU144855","chr2:38294651-38303710 (-) // 98.62 // p22.2","cytochrome P450, family 1, subfamily B, polypeptide 1","CYP1B1","OTTHUMG00000100970","1545","231300 /// 600975 /// 601771 /// 604229","NP_000095","NM_000104","0001525 // angiogenesis // inferred from electronic annotation /// 0002930 // trabecular meshwork development // inferred from sequence or structural similarity /// 0006725 // cellular aromatic compound metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006809 // nitric oxide biosynthetic process // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0007601 // visual perception // traceable author statement /// 0008202 // steroid metabolic process // inferred from direct assay /// 0008210 // estrogen metabolic process // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from sequence or structural similarity /// 0009404 // toxin metabolic process // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from sequence or structural similarity /// 0016125 // sterol metabolic process // traceable author statement /// 0019369 // arachidonic acid metabolic process // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // traceable author statement /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0033629 // negative regulation of cell adhesion mediated by integrin // inferred from sequence or structural similarity /// 0042572 // retinol metabolic process // inferred from direct assay /// 0042574 // retinal metabolic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0046427 // positive regulation of JAK-STAT cascade // inferred from sequence or structural similarity /// 0046466 // membrane lipid catabolic process // inferred from sequence or structural similarity /// 0048514 // blood vessel morphogenesis // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // traceable author statement /// 0061298 // retina vasculature development in camera-type eye // inferred from electronic annotation /// 0061304 // retinal blood vessel morphogenesis // inferred from sequence or structural similarity /// 0070301 // cellular response to hydrogen peroxide // inferred from sequence or structural similarity /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay /// 0071603 // endothelial cell-cell adhesion // inferred from electronic annotation /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement /// 1901313 // positive regulation of gene expression involved in extracellular matrix organization // inferred from sequence or structural similarity /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from sequence or structural similarity","0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation","0004497 // monooxygenase activity // inferred from direct assay /// 0004497 // monooxygenase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from direct assay /// 0019825 // oxygen binding // traceable author statement /// 0020037 // heme binding // inferred from direct assay /// 0020037 // heme binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation","---","IPR001128 // Cytochrome P450 // 2.5E-105"
"202437_s_at",3.192069568,3.503820862,2.287740418,"UP","NM_000104","chr2:38294745-38303292 (-) // 99.4 // p22.2","cytochrome P450, family 1, subfamily B, polypeptide 1","CYP1B1","OTTHUMG00000100970","1545","231300 /// 600975 /// 601771 /// 604229","NP_000095","NM_000104","0001525 // angiogenesis // inferred from electronic annotation /// 0002930 // trabecular meshwork development // inferred from sequence or structural similarity /// 0006725 // cellular aromatic compound metabolic process // inferred from electronic annotation /// 0006805 // xenobiotic metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0006809 // nitric oxide biosynthetic process // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0007601 // visual perception // traceable author statement /// 0008202 // steroid metabolic process // inferred from direct assay /// 0008210 // estrogen metabolic process // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from sequence or structural similarity /// 0009404 // toxin metabolic process // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from sequence or structural similarity /// 0016125 // sterol metabolic process // traceable author statement /// 0019369 // arachidonic acid metabolic process // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019373 // epoxygenase P450 pathway // traceable author statement /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from sequence or structural similarity /// 0033629 // negative regulation of cell adhesion mediated by integrin // inferred from sequence or structural similarity /// 0042572 // retinol metabolic process // inferred from direct assay /// 0042574 // retinal metabolic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from sequence or structural similarity /// 0044281 // small molecule metabolic process // traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0046427 // positive regulation of JAK-STAT cascade // inferred from sequence or structural similarity /// 0046466 // membrane lipid catabolic process // inferred from sequence or structural similarity /// 0048514 // blood vessel morphogenesis // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // traceable author statement /// 0061298 // retina vasculature development in camera-type eye // inferred from electronic annotation /// 0061304 // retinal blood vessel morphogenesis // inferred from sequence or structural similarity /// 0070301 // cellular response to hydrogen peroxide // inferred from sequence or structural similarity /// 0071407 // cellular response to organic cyclic compound // inferred from direct assay /// 0071603 // endothelial cell-cell adhesion // inferred from electronic annotation /// 0097267 // omega-hydroxylase P450 pathway // traceable author statement /// 1901313 // positive regulation of gene expression involved in extracellular matrix organization // inferred from sequence or structural similarity /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from sequence or structural similarity","0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation","0004497 // monooxygenase activity // inferred from direct assay /// 0004497 // monooxygenase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from direct assay /// 0019825 // oxygen binding // traceable author statement /// 0020037 // heme binding // inferred from direct assay /// 0020037 // heme binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070330 // aromatase activity // inferred from electronic annotation","---","IPR001128 // Cytochrome P450 // 2.5E-105"
"202458_at",2.102582416,1.377506852,1.206510236,"UP","NM_007173","chr11:86511602-86520212 (+) // 97.45 // q14.2","protease, serine, 23","PRSS23","ENSG00000150687 /// OTTHUMG00000167226","11098","---","NP_001280107 /// NP_001280108 /// NP_001280109 /// NP_009104 /// XP_005273784","NM_001293178 /// NM_001293179 /// NM_001293180 /// NM_007173 /// NR_120591 /// NR_120592 /// NR_120593 /// XM_005273727 /// XR_424260 /// XR_428964 /// XR_432738","0006508 // proteolysis // inferred from electronic annotation","0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation","---","IPR001254 // Peptidase S1 // 8.7E-14"
"202524_s_at",1.522707516,1.692702269,1.192859259,"UP","NM_014767","chr10:73818792-73848767 (-) // 97.61 // q22.1","sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2","SPOCK2","ENSG00000107742 /// OTTHUMG00000018430","9806","607988","NP_001127906 /// NP_001231879 /// NP_055582 /// XP_005270359","NM_001134434 /// NM_001244950 /// NM_014767 /// XM_005270302","0007165 // signal transduction // inferred from electronic annotation /// 0007416 // synapse assembly // non-traceable author statement /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0019800 // peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan // inferred from electronic annotation /// 0030198 // extracellular matrix organization // non-traceable author statement /// 0045595 // regulation of cell differentiation // non-traceable author statement","0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement","0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005539 // glycosaminoglycan binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation","---","IPR000716 // Thyroglobulin type-1 // 3.1E-20 /// IPR002350 // Kazal domain // 1.7E-12 /// IPR002350 // Kazal domain // 2.2E-10 /// IPR019577 // SPARC/Testican, calcium-binding domain // 4.8E-34"
"202528_at",2.087757884,2.300952764,1.8185426,"UP","NM_000403","chr1:24122089-24125926 (-) // 99.86 // p36.11","UDP-galactose-4-epimerase","GALE","ENSG00000117308 /// OTTHUMG00000002958","2582","230350 /// 606953","NP_000394 /// NP_001008217 /// NP_001121093","NM_000403 /// NM_001008216 /// NM_001127621","0005975 // carbohydrate metabolic process // traceable author statement /// 0006012 // galactose metabolic process // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0019388 // galactose catabolic process // inferred from direct assay /// 0019388 // galactose catabolic process // traceable author statement /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045226 // extracellular polysaccharide biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation","0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0003824 // catalytic activity // inferred from electronic annotation /// 0003854 // 3-beta-hydroxy-delta5-steroid dehydrogenase activity // inferred from electronic annotation /// 0003978 // UDP-glucose 4-epimerase activity // not recorded /// 0003978 // UDP-glucose 4-epimerase activity // inferred from direct assay /// 0008831 // dTDP-4-dehydrorhamnose reductase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016857 // racemase and epimerase activity, acting on carbohydrates and derivatives // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0050662 // coenzyme binding // inferred from electronic annotation","COLANSYN-PWY // HumanCyc /// GALACTMETAB-PWY // HumanCyc /// P61-PWY // HumanCyc /// PWY-3821 // HumanCyc /// PWY-5514 // HumanCyc /// PWY-6317 // HumanCyc","IPR001509 // NAD-dependent epimerase/dehydratase, N-terminal domain // 1.9E-55 /// IPR002198 // Short-chain dehydrogenase/reductase SDR // 7.2E-14 /// IPR002225 // 3-beta hydroxysteroid dehydrogenase/isomerase // 1.1E-18 /// IPR003869 // Polysaccharide biosynthesis protein, CapD-like domain // 1.2E-13 /// IPR005913 // dTDP-4-dehydrorhamnose reductase // 4.7E-14 /// IPR013120 // Male sterility, NAD-binding // 9.9E-12 /// IPR013968 // Polyketide synthase, KR // 4.1E-10"
"202554_s_at",-1.506612027,-1.045734929,-1.106277987,"DOWN","AL527430","chr1:110278352-110283629 (-) // 61.13 // p13.3","glutathione S-transferase mu 3 (brain)","GSTM3","ENSG00000134202 /// OTTHUMG00000011640","2947","138390","NP_000840","NM_000849 /// NR_024537","0006749 // glutathione metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008065 // establishment of blood-nerve barrier // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0018916 // nitrobenzene metabolic process // inferred from direct assay /// 0042178 // xenobiotic catabolic process // inferred from direct assay /// 0043627 // response to estrogen // inferred from expression pattern /// 0044281 // small molecule metabolic process // traceable author statement /// 0070458 // cellular detoxification of nitrogen compound // inferred from direct assay /// 1901687 // glutathione derivative biosynthetic process // traceable author statement","0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0004364 // glutathione transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043295 // glutathione binding // inferred from direct assay","Circadian_Exercise // GenMAPP /// PWY-4061 // HumanCyc","IPR004045 // Glutathione S-transferase, N-terminal // 1.1E-24 /// IPR004046 // Glutathione S-transferase, C-terminal // 2.3E-21"
"202609_at",1.72578286,1.188902357,1.272970622,"UP","NM_004447","chr12:15773097-15942282 (-) // 99.95 // p12.3","epidermal growth factor receptor pathway substrate 8","EPS8","ENSG00000151491 /// OTTHUMG00000168787","2059","600206","NP_004438 /// XP_005253396 /// XP_005253397 /// XP_006719120","NM_004447 /// XM_005253339 /// XM_005253340 /// XM_006719057","0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from sequence or structural similarity /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0010458 // exit from mitosis // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016601 // Rac protein signal transduction // inferred from sequence or structural similarity /// 0030832 // regulation of actin filament length // inferred from sequence or structural similarity /// 0031532 // actin cytoskeleton reorganization // inferred from electronic annotation /// 0036336 // dendritic cell migration // inferred from sequence or structural similarity /// 0048149 // behavioral response to ethanol // inferred from electronic annotation /// 0051016 // barbed-end actin filament capping // inferred from sequence or structural similarity /// 0051017 // actin filament bundle assembly // inferred from sequence or structural similarity /// 0051764 // actin crosslink formation // inferred from sequence or structural similarity /// 0070358 // actin polymerization-dependent cell motility // inferred from sequence or structural similarity","0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005938 // cell cortex // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0017146 // N-methyl-D-aspartate selective glutamate receptor complex // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0032420 // stereocilium // inferred from sequence or structural similarity /// 0032587 // ruffle membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0003779 // actin binding // inferred from sequence or structural similarity /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0048365 // Rac GTPase binding // inferred from sequence or structural similarity","---","IPR001452 // SH3 domain // 4.0E-14 /// IPR006020 // PTB/PI domain // 1.6E-11 /// IPR006020 // PTB/PI domain // 5.3E-10 /// IPR011511 // Variant SH3 domain // 4.7E-10 /// IPR013625 // Tensin phosphotyrosine-binding domain // 1.1E-58 /// IPR013625 // Tensin phosphotyrosine-binding domain // 4.1E-57"
"202709_at",-1.684364189,-1.070579915,-1.403392503,"DOWN","NM_002023","chr1:203309756-203317403 (-) // 98.95 // q32.1","fibromodulin","FMOD","ENSG00000122176 /// OTTHUMG00000035910","2331","600245","NP_002014","NM_002023 /// NR_103757","0005975 // carbohydrate metabolic process // traceable author statement /// 0007181 // transforming growth factor beta receptor complex assembly // traceable author statement /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0042340 // keratan sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement","0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0043202 // lysosomal lumen // traceable author statement","0005515 // protein binding // inferred from electronic annotation","---","IPR000372 // Leucine-rich repeat-containing N-terminal // 1.3E-12 /// IPR001611 // Leucine-rich repeat // 5.3E-5 /// IPR001611 // Leucine-rich repeat // 4.9E-6 /// IPR001611 // Leucine-rich repeat // 7.2E-5 /// IPR001611 // Leucine-rich repeat // 9.7E-6 /// IPR001611 // Leucine-rich repeat // 9.1E-5"
"202733_at",1.835860601,1.674080109,1.682457764,"UP","NM_004199","chr5:131528302-131562559 (-) // 98.81 // q31.1","uncharacterized LOC101927705 /// prolyl 4-hydroxylase, alpha polypeptide II","LOC101927705 /// P4HA2","ENSG00000072682 /// OTTHUMG00000059647","8974 /// 101927705","600608","NP_001017973 /// NP_001017974 /// NP_001136070 /// NP_001136071 /// NP_004190 /// XP_005272173 /// XP_005272174 /// XP_005272175 /// XP_005272176 /// XP_005272177 /// XP_005272179 /// XP_006714791 /// XP_006714792 /// XP_006714793 /// XP_006714794","NM_001017973 /// NM_001017974 /// NM_001142598 /// NM_001142599 /// NM_004199 /// XM_005272116 /// XM_005272117 /// XM_005272118 /// XM_005272119 /// XM_005272120 /// XM_005272122 /// XM_006714728 /// XM_006714729 /// XM_006714730 /// XM_006714731 /// XR_246585 /// XR_249830 /// XR_251870","0018401 // peptidyl-proline hydroxylation to 4-hydroxy-L-proline // inferred from electronic annotation /// 0019511 // peptidyl-proline hydroxylation // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation","0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay","0004656 // procollagen-proline 4-dioxygenase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016702 // oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen // inferred from electronic annotation /// 0016705 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation","---","IPR005123 // Oxoglutarate/iron-dependent dioxygenase // 3.2E-15 /// IPR005123 // Oxoglutarate/iron-dependent dioxygenase // 2.3E-15 /// IPR013547 // Prolyl 4-hydroxylase alpha-subunit, N-terminal // 1.9E-45"
"202748_at",1.676029497,1.210899106,1.079670135,"UP","NM_004120","chr1:89573682-89591686 (-) // 99.76 // p22.2","guanylate binding protein 2, interferon-inducible","GBP2","ENSG00000162645 /// OTTHUMG00000010662","2634","600412","NP_004111","NM_004120","0006184 // GTP catabolic process // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement","0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation","0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation","---","IPR003191 // Guanylate-binding protein, C-terminal // 9.0E-132 /// IPR015894 // Guanylate-binding protein, N-terminal // 3.7E-129"
"202833_s_at",3.417556331,3.89743647,3.77405374,"UP","NM_000295","chr14:94844709-94849578 (-) // 98.22 // q32.13","serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1","SERPINA1","ENSG00000197249 /// OTTHUMG00000150355","5265","107400 /// 606963 /// 613490","NP_000286 /// NP_001002235 /// NP_001002236 /// NP_001121172 /// NP_001121173 /// NP_001121174 /// NP_001121175 /// NP_001121176 /// NP_001121177 /// NP_001121178 /// NP_001121179","NM_000295 /// NM_001002235 /// NM_001002236 /// NM_001127700 /// NM_001127701 /// NM_001127702 /// NM_001127703 /// NM_001127704 /// NM_001127705 /// NM_001127706 /// NM_001127707","0001666 // response to hypoxia // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030162 // regulation of proteolysis // not recorded /// 0030168 // platelet activation // traceable author statement /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033986 // response to methanol // inferred from electronic annotation /// 0034014 // response to triglyceride // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0046687 // response to chromate // inferred from electronic annotation","0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from mutant phenotype /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0001948 // glycoprotein binding // inferred from physical interaction /// 0002020 // protease binding // inferred from physical interaction /// 0004866 // endopeptidase inhibitor activity // inferred from electronic annotation /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0004867 // serine-type endopeptidase inhibitor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction","---","IPR023796 // Serpin domain // 4.7E-122 /// IPR023796 // Serpin domain // 6.8E-82 /// IPR023796 // Serpin domain // 3.9E-99"
"202901_x_at",1.539508894,1.375469621,1.156439127,"UP","BC002642","chr1:150704857-150738234 (-) // 80.88 // q21.3","cathepsin S","CTSS","ENSG00000163131 /// OTTHUMG00000035010","1520","116845","NP_001186668 /// NP_004070","NM_001199739 /// NM_004079","0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002250 // adaptive immune response // inferred from expression pattern /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0006955 // immune response // traceable author statement /// 0019882 // antigen processing and presentation // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // inferred from direct assay /// 0034769 // basement membrane disassembly // inferred from direct assay /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from direct assay /// 0097067 // cellular response to thyroid hormone stimulus // inferred from expression pattern","0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0036021 // endolysosome lumen // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay","0001968 // fibronectin binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0005518 // collagen binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043236 // laminin binding // inferred from direct assay /// 0043394 // proteoglycan binding // inferred from physical interaction","---","IPR000668 // Peptidase C1A, papain C-terminal // 8.9E-87 /// IPR013201 // Proteinase inhibitor I29, cathepsin propeptide // 2.5E-17"
"202908_at",-1.362410224,-1.030440779,-1.160511697,"DOWN","NM_006005","chr4:6271576-6304992 (+) // 99.89 // p16.1","Wolfram syndrome 1 (wolframin)","WFS1","ENSG00000109501 /// OTTHUMG00000090431","7466","116400 /// 125853 /// 222300 /// 600965 /// 606201 /// 614296","NP_001139325 /// NP_005996","NM_001145853 /// NM_006005","0001822 // kidney development // inferred from mutant phenotype /// 0003091 // renal water homeostasis // inferred from mutant phenotype /// 0006983 // ER overload response // inferred by curator /// 0006983 // ER overload response // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007601 // visual perception // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0022417 // protein maturation by protein folding // inferred by curator /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from sequence or structural similarity /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0031398 // positive regulation of protein ubiquitination // inferred from sequence or structural similarity /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from direct assay /// 0034976 // response to endoplasmic reticulum stress // inferred from direct assay /// 0042048 // olfactory behavior // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043069 // negative regulation of programmed cell death // inferred from mutant phenotype /// 0043433 // negative regulation of sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptotic process // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045862 // positive regulation of proteolysis // inferred from sequence or structural similarity /// 0045927 // positive regulation of growth // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0050877 // neurological system process // inferred from mutant phenotype /// 0051247 // positive regulation of protein metabolic process // inferred from direct assay /// 0051928 // positive regulation of calcium ion transport // inferred from direct assay /// 0055074 // calcium ion homeostasis // inferred from direct assay /// 0070845 // polyubiquitinated misfolded protein transport // inferred from sequence or structural similarity /// 1902236 // negative regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from sequence or structural similarity /// 2000675 // negative regulation of type B pancreatic cell apoptotic process // inferred from mutant phenotype","0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0030425 // dendrite // inferred from sequence or structural similarity","0005215 // transporter activity // inferred from sequence or structural similarity /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from sequence or structural similarity /// 0033613 // activating transcription factor binding // inferred from sequence or structural similarity /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation /// 0051117 // ATPase binding // inferred from physical interaction","---","---"
"202920_at",-2.202781912,-1.634123567,-1.695648586,"DOWN","BF726212","chr4:113970869-114304892 (+) // 99.44 // q25","ankyrin 2, neuronal","ANK2","ENSG00000145362 /// OTTHUMG00000132912","287","106410 /// 600919","NP_001120965 /// NP_001139 /// NP_066187 /// XP_005262999 /// XP_005263002 /// XP_005263005 /// XP_006714250 /// XP_006714251 /// XP_006714252 /// XP_006714253 /// XP_006714254 /// XP_006714255 /// XP_006714256 /// XP_006714257","NM_001127493 /// NM_001148 /// NM_020977 /// XM_005262942 /// XM_005262945 /// XM_005262948 /// XM_006714187 /// XM_006714188 /// XM_006714189 /// XM_006714190 /// XM_006714191 /// XM_006714192 /// XM_006714193 /// XM_006714194","0002027 // regulation of heart rate // inferred from mutant phenotype /// 0003283 // atrial septum development // inferred from mutant phenotype /// 0006874 // cellular calcium ion homeostasis // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from genetic interaction /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from genetic interaction /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from sequence or structural similarity /// 0010882 // regulation of cardiac muscle contraction by calcium ion signaling // inferred from mutant phenotype /// 0030913 // paranodal junction assembly // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred by curator /// 0033292 // T-tubule organization // inferred from sequence or structural similarity /// 0033365 // protein localization to organelle // inferred from genetic interaction /// 0034394 // protein localization to cell surface // inferred from sequence or structural similarity /// 0034613 // cellular protein localization // inferred from genetic interaction /// 0036309 // protein localization to M-band // inferred from sequence or structural similarity /// 0036371 // protein localization to T-tubule // inferred from sequence or structural similarity /// 0043268 // positive regulation of potassium ion transport // inferred from sequence or structural similarity /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0051279 // regulation of release of sequestered calcium ion into cytosol // inferred from genetic interaction /// 0051597 // response to methylmercury // inferred from electronic annotation /// 0051924 // regulation of calcium ion transport // inferred from genetic interaction /// 0051928 // positive regulation of calcium ion transport // inferred from sequence or structural similarity /// 0055117 // regulation of cardiac muscle contraction // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from electronic annotation /// 0060307 // regulation of ventricular cardiac muscle cell membrane repolarization // inferred from mutant phenotype /// 0070296 // sarcoplasmic reticulum calcium ion transport // traceable author statement /// 0070972 // protein localization to endoplasmic reticulum // inferred from genetic interaction /// 0072659 // protein localization to plasma membrane // inferred from genetic interaction /// 0072659 // protein localization to plasma membrane // inferred from sequence or structural similarity /// 0072661 // protein targeting to plasma membrane // inferred from electronic annotation /// 0086004 // regulation of cardiac muscle cell contraction // inferred from genetic interaction /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0086014 // atrial cardiac muscle cell action potential // inferred from mutant phenotype /// 0086015 // SA node cell action potential // inferred from sequence or structural similarity /// 0086036 // regulation of cardiac muscle cell membrane potential // inferred from electronic annotation /// 0086046 // membrane depolarization during SA node cell action potential // traceable author statement /// 0086066 // atrial cardiac muscle cell to AV node cell communication // inferred from sequence or structural similarity /// 0086070 // SA node cell to atrial cardiac muscle cell communication // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from sequence or structural similarity /// 1901018 // positive regulation of potassium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 1901019 // regulation of calcium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 1901021 // positive regulation of calcium ion transmembrane transporter activity // inferred from sequence or structural similarity /// 2001257 // regulation of cation channel activity // inferred from electronic annotation /// 2001259 // positive regulation of cation channel activity // inferred from sequence or structural similarity","0005622 // intracellular // inferred from genetic interaction /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030315 // T-tubule // inferred from sequence or structural similarity /// 0031430 // M band // inferred from sequence or structural similarity /// 0031672 // A band // inferred from sequence or structural similarity /// 0042383 // sarcolemma // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from electronic annotation /// 0043034 // costamere // inferred from sequence or structural similarity /// 0045121 // membrane raft // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation","0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015459 // potassium channel regulator activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0030507 // spectrin binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from sequence or structural similarity /// 0044325 // ion channel binding // inferred from physical interaction /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0051117 // ATPase binding // inferred from sequence or structural similarity","---","IPR000488 // Death domain // 1.3E-23 /// IPR000488 // Death domain // 2.5E-23 /// IPR000488 // Death domain // 3.2E-24 /// IPR000488 // Death domain // 1.7E-24 /// IPR000906 // ZU5 domain // 1.2E-31 /// IPR000906 // ZU5 domain // 2.7E-22 /// IPR000906 // ZU5 domain // 2.2E-31 /// IPR000906 // ZU5 domain // 6.3E-22 /// IPR000906 // ZU5 domain // 3.9E-44 /// IPR002110 // Ankyrin repeat // 2.4E-9 /// IPR002110 // Ankyrin repeat // 4.1E-13 /// IPR002110 // Ankyrin repeat // 6.1E-12 /// IPR002110 // Ankyrin repeat // 3.2E-12 /// IPR002110 // Ankyrin repeat // 9.7E-14 /// IPR002110 // Ankyrin repeat // 1.1E-13 /// IPR002110 // Ankyrin repeat // 4.9E-10 /// IPR002110 // Ankyrin repeat // 1.6E-11 /// IPR002110 // Ankyrin repeat // 1.9E-12 /// IPR002110 // Ankyrin repeat // 2.5E-12 /// IPR002110 // Ankyrin repeat // 1.2E-11 /// IPR002110 // Ankyrin repeat // 2.3E-11 /// IPR002110 // Ankyrin repeat // 2.3E-9 /// IPR002110 // Ankyrin repeat // 4.6E-11 /// IPR002110 // Ankyrin repeat // 6.5E-11 /// IPR002110 // Ankyrin repeat // 2.4E-12 /// IPR002110 // Ankyrin repeat // 3.0E-13 /// IPR002110 // Ankyrin repeat // 4.2E-8 /// IPR002110 // Ankyrin repeat // 3.2E-13 /// IPR002110 // Ankyrin repeat // 2.2E-13 /// IPR002110 // Ankyrin repeat // 5.6E-9 /// IPR002110 // Ankyrin repeat // 9.4E-13 /// IPR002110 // Ankyrin repeat // 1.4E-11 /// IPR002110 // Ankyrin repeat // 7.4E-12 /// IPR002110 // Ankyrin repeat // 2.2E-13 /// IPR002110 // Ankyrin repeat // 2.5E-13 /// IPR002110 // Ankyrin repeat // 1.1E-9 /// IPR002110 // Ankyrin repeat // 3.7E-11 /// IPR002110 // Ankyrin repeat // 4.4E-12 /// IPR002110 // Ankyrin repeat // 5.7E-12 /// IPR002110 // Ankyrin repeat // 2.8E-11 /// IPR002110 // Ankyrin repeat // 5.3E-11 /// IPR002110 // Ankyrin repeat // 5.1E-9 /// IPR002110 // Ankyrin repeat // 1.0E-10 /// IPR002110 // Ankyrin repeat // 1.5E-10 /// IPR002110 // Ankyrin repeat // 5.5E-12 /// IPR002110 // Ankyrin repeat // 6.8E-13 /// IPR002110 // Ankyrin repeat // 7.2E-13 /// IPR002110 // Ankyrin repeat // 5.1E-13"
"203021_at",1.801720477,2.059302451,2.242269544,"UP","NM_003064","chr20:43880878-43883202 (-) // 85.35 // q13.12","secretory leukocyte peptidase inhibitor","SLPI","ENSG00000124107 /// OTTHUMG00000033075","6590","107285","NP_003055","NM_003064","0006508 // proteolysis // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0032091 // negative regulation of protein binding // inferred from direct assay /// 0045071 // negative regulation of viral genome replication // inferred from direct assay","0005576 // extracellular region // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation","---","IPR008197 // Whey acidic protein-type  4-disulphide core // 1.9E-13 /// IPR008197 // Whey acidic protein-type  4-disulphide core // 1.8E-12"
"203060_s_at",-2.003998723,-2.23746188,-2.184925592,"DOWN","AF074331","chr10:89419675-89507460 (+) // 89.67 // q23.2","3'-phosphoadenosine 5'-phosphosulfate synthase 2","PAPSS2","ENSG00000198682 /// OTTHUMG00000018683","9060","603005 /// 612847","NP_001015880 /// NP_004661","NM_001015880 /// NM_004670","0000103 // sulfate assimilation // inferred from electronic annotation /// 0001501 // skeletal system development // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0007596 // blood coagulation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0050427 // 3'-phosphoadenosine 5'-phosphosulfate metabolic process // traceable author statement /// 0050428 // 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process // traceable author statement /// 0060348 // bone development // inferred from electronic annotation","0005829 // cytosol // traceable author statement","0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004020 // adenylylsulfate kinase activity // inferred from electronic annotation /// 0004781 // sulfate adenylyltransferase (ATP) activity // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from sequence or structural similarity","DISSULFRED-PWY // MetaCyc /// P224-PWY // MetaCyc /// PWY-5278 // MetaCyc /// PWY-5340 // HumanCyc /// PWY-5340 // MetaCyc /// PWY-6683 // MetaCyc /// SULFMETII-PWY // MetaCyc","IPR002891 // Adenylylsulphate kinase // 3.4E-75 /// IPR002891 // Adenylylsulphate kinase // 3.5E-75 /// IPR024951 // Sulphate adenylyltransferase catalytic domain // 1.5E-98 /// IPR024951 // Sulphate adenylyltransferase catalytic domain // 9.0E-99"
"203083_at",1.339750533,1.174050761,1.012076859,"UP","NM_003247","chr6:169615882-169654128 (-) // 93.95 // q27","thrombospondin 2","THBS2","ENSG00000186340 /// OTTHUMG00000045408","7058","188061 /// 603932","NP_003238","NM_003247","0007155 // cell adhesion // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0051965 // positive regulation of synapse assembly // inferred from electronic annotation","0005576 // extracellular region // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation","0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation","---","IPR000742 // Epidermal growth factor-like domain // 6.0E-9 /// IPR000884 // Thrombospondin, type 1 repeat // 1.2E-15 /// IPR000884 // Thrombospondin, type 1 repeat // 7.7E-19 /// IPR000884 // Thrombospondin, type 1 repeat // 2.2E-19 /// IPR001007 // von Willebrand factor, type C // 2.6E-17 /// IPR001881 // EGF-like calcium-binding domain // 5.8E-10 /// IPR003367 // Thrombospondin, type 3-like repeat // 2.3E-5 /// IPR003367 // Thrombospondin, type 3-like repeat // 0.0039 /// IPR003367 // Thrombospondin, type 3-like repeat // 1.7E-4 /// IPR003367 // Thrombospondin, type 3-like repeat // 1.2E-4 /// IPR003367 // Thrombospondin, type 3-like repeat // 0.035 /// IPR003367 // Thrombospondin, type 3-like repeat // 2.1E-5 /// IPR003367 // Thrombospondin, type 3-like repeat // 8.1E-4 /// IPR003367 // Thrombospondin, type 3-like repeat // 1.0E-5 /// IPR003367 // Thrombospondin, type 3-like repeat // 0.0018 /// IPR003367 // Thrombospondin, type 3-like repeat // 3.4E-4 /// IPR003367 // Thrombospondin, type 3-like repeat // 0.0014 /// IPR008859 // Thrombospondin, C-terminal // 2.0E-99"
"203126_at",-1.711964307,-1.266338403,-1.23025499,"DOWN","NM_014214","chr18:11981454-12030876 (+) // 98.8 // p11.21","inositol(myo)-1(or 4)-monophosphatase 2","IMPA2","ENSG00000141401 /// OTTHUMG00000131693","3613","605922","NP_055029","NM_014214","0006021 // inositol biosynthetic process // inferred from electronic annotation /// 0006796 // phosphate-containing compound metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046854 // phosphatidylinositol phosphorylation // inferred from electronic annotation /// 0046855 // inositol phosphate dephosphorylation // inferred from direct assay","0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement","0008934 // inositol monophosphate 1-phosphatase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0052832 // inositol monophosphate 3-phosphatase activity // inferred from electronic annotation /// 0052833 // inositol monophosphate 4-phosphatase activity // inferred from electronic annotation /// 0052834 // inositol monophosphate phosphatase activity // inferred from electronic annotation","PWY-2301 // HumanCyc","IPR000760 // Inositol monophosphatase // 1.4E-84 /// IPR000760 // Inositol monophosphatase // 2.2E-38"
"203178_at",-1.871010442,-1.303840865,-1.444372022,"DOWN","NM_001482","chr15:45653323-45670706 (-) // 97.68 // q21.1","glycine amidinotransferase (L-arginine:glycine amidinotransferase)","GATM","ENSG00000171766 /// OTTHUMG00000131427","2628","602360 /// 612718","NP_001473","NM_001482 /// XR_424635 /// XR_429525 /// XR_433091","0006600 // creatine metabolic process // traceable author statement /// 0006601 // creatine biosynthetic process // inferred from direct assay /// 0006601 // creatine biosynthetic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042246 // tissue regeneration // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046689 // response to mercury ion // inferred from electronic annotation","0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0015067 // amidinotransferase activity // inferred from electronic annotation /// 0015068 // glycine amidinotransferase activity // inferred from direct assay /// 0015068 // glycine amidinotransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016813 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines // inferred from electronic annotation","GLYCGREAT-PWY // HumanCyc","---"
"203180_at",2.819191739,1.684349095,2.648944042,"UP","NM_000693","chr15:101420060-101456829 (+) // 98.84 // q26.3","aldehyde dehydrogenase 1 family, member A3","ALDH1A3","ENSG00000184254 /// OTTHUMG00000186439","220","600463 /// 615113","NP_000684 /// NP_001280744","NM_000693 /// NM_001037224 /// NM_001293815 /// XR_109231 /// XR_111558 /// XR_172102 /// XR_243247 /// XR_248182 /// XR_253467","0002072 // optic cup morphogenesis involved in camera-type eye development // inferred from electronic annotation /// 0002138 // retinoic acid biosynthetic process // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0021768 // nucleus accumbens development // inferred from electronic annotation /// 0031076 // embryonic camera-type eye development // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042572 // retinol metabolic process // inferred from electronic annotation /// 0042573 // retinoic acid metabolic process // inferred from direct assay /// 0042574 // retinal metabolic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0048048 // embryonic eye morphogenesis // inferred from sequence or structural similarity /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0060013 // righting reflex // inferred from electronic annotation /// 0060166 // olfactory pit development // inferred from electronic annotation /// 0060324 // face development // inferred from electronic annotation","0005737 // cytoplasm // inferred from direct assay","0004029 // aldehyde dehydrogenase (NAD) activity // inferred from electronic annotation /// 0004030 // aldehyde dehydrogenase [NAD(P)+] activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0070324 // thyroid hormone binding // inferred from electronic annotation /// 0070403 // NAD+ binding // inferred from electronic annotation","---","IPR015590 // Aldehyde dehydrogenase domain // 3.0E-193 /// IPR015590 // Aldehyde dehydrogenase domain // 3.6E-18 /// IPR015590 // Aldehyde dehydrogenase domain // 1.4E-124"
"203234_at",1.684585118,1.991162425,1.254036282,"UP","NM_003364","chr7:48128861-48148015 (+) // 99.33 // p12.3","uridine phosphorylase 1","UPP1","ENSG00000183696 /// OTTHUMG00000129253","7378","191730","NP_001274355 /// NP_001274357 /// NP_001274358 /// NP_001274359 /// NP_003355 /// XP_005249895 /// XP_006715834","NM_001287426 /// NM_001287428 /// NM_001287429 /// NM_001287430 /// NM_003364 /// NM_181597 /// NR_109837 /// XM_005249838 /// XM_006715771","0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006220 // pyrimidine nucleotide metabolic process // inferred from electronic annotation /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0009166 // nucleotide catabolic process // inferred from electronic annotation /// 0042149 // cellular response to glucose starvation // inferred from electronic annotation /// 0043097 // pyrimidine nucleoside salvage // traceable author statement /// 0044206 // UMP salvage // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046108 // uridine metabolic process // inferred from electronic annotation /// 0046135 // pyrimidine nucleoside catabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement","0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement","0003824 // catalytic activity // inferred from electronic annotation /// 0004850 // uridine phosphorylase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016763 // transferase activity, transferring pentosyl groups // inferred from electronic annotation","DRIBOPMET-PWY // HumanCyc /// PWY0-1295 // HumanCyc /// PWY0-163 // HumanCyc","IPR000845 // Nucleoside phosphorylase domain // 4.8E-33"
"203240_at",-2.150086754,-1.285119669,-1.273201533,"DOWN","NM_003890","chr19:40353970-40440533 (-) // 99.79 // q13.2","Fc fragment of IgG binding protein","FCGBP","OTTHUMG00000182580","8857","---","NP_003881","NM_003890","---","0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005515 // protein binding // inferred from physical interaction","---","IPR001846 // von Willebrand factor, type D domain // 1.1E-39 /// IPR001846 // von Willebrand factor, type D domain // 1.4E-33 /// IPR001846 // von Willebrand factor, type D domain // 4.2E-39 /// IPR001846 // von Willebrand factor, type D domain // 9.2E-36 /// IPR001846 // von Willebrand factor, type D domain // 2.7E-33 /// IPR001846 // von Willebrand factor, type D domain // 3.9E-38 /// IPR001846 // von Willebrand factor, type D domain // 9.2E-36 /// IPR001846 // von Willebrand factor, type D domain // 4.6E-33 /// IPR001846 // von Willebrand factor, type D domain // 9.9E-38 /// IPR001846 // von Willebrand factor, type D domain // 1.6E-35 /// IPR001846 // von Willebrand factor, type D domain // 4.7E-32 /// IPR001846 // von Willebrand factor, type D domain // 4.5E-32 /// IPR001846 // von Willebrand factor, type D domain // 1.7E-18 /// IPR002919 // Trypsin Inhibitor-like, cysteine rich domain // 6.1E-15 /// IPR002919 // Trypsin Inhibitor-like, cysteine rich domain // 5.6E-14 /// IPR002919 // Trypsin Inhibitor-like, cysteine rich domain // 2.8E-14 /// IPR002919 // Trypsin Inhibitor-like, cysteine rich domain // 1.3E-13 /// IPR002919 // Trypsin Inhibitor-like, cysteine rich domain // 1.5E-15 /// IPR002919 // Trypsin Inhibitor-like, cysteine rich domain // 2.6E-14 /// IPR002919 // Trypsin Inhibitor-like, cysteine rich domain // 1.6E-13 /// IPR002919 // Trypsin Inhibitor-like, cysteine rich domain // 1.5E-15 /// IPR002919 // Trypsin Inhibitor-like, cysteine rich domain // 2.6E-14 /// IPR002919 // Trypsin Inhibitor-like, cysteine rich domain // 1.6E-13 /// IPR002919 // Trypsin Inhibitor-like, cysteine rich domain // 1.8E-15 /// IPR002919 // Trypsin Inhibitor-like, cysteine rich domain // 3.9E-12 /// IPR014853 // Uncharacterised domain, cysteine-rich // 1.6E-22 /// IPR014853 // Uncharacterised domain, cysteine-rich // 5.1E-24 /// IPR014853 // Uncharacterised domain, cysteine-rich // 8.0E-23 /// IPR014853 // Uncharacterised domain, cysteine-rich // 4.5E-23 /// IPR014853 // Uncharacterised domain, cysteine-rich // 3.4E-22 /// IPR014853 // Uncharacterised domain, cysteine-rich // 6.6E-23 /// IPR014853 // Uncharacterised domain, cysteine-rich // 4.5E-23 /// IPR014853 // Uncharacterised domain, cysteine-rich // 3.4E-22 /// IPR014853 // Uncharacterised domain, cysteine-rich // 7.2E-23 /// IPR014853 // Uncharacterised domain, cysteine-rich // 3.7E-23 /// IPR014853 // Uncharacterised domain, cysteine-rich // 4.3E-22 /// IPR014853 // Uncharacterised domain, cysteine-rich // 4.8E-25"
"203256_at",2.436603207,2.676765285,2.904140642,"UP","NM_001793","chr16:68679229-68732931 (+) // 99.78 // q22.1","cadherin 3, type 1, P-cadherin (placental)","CDH3","ENSG00000062038 /// OTTHUMG00000137560","1001","114021 /// 225280 /// 601553","NP_001784","NM_001793","0001895 // retina homeostasis // inferred from mutant phenotype /// 0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007601 // visual perception // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010838 // positive regulation of keratinocyte proliferation // inferred from mutant phenotype /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0022405 // hair cycle process // inferred from mutant phenotype /// 0031424 // keratinization // inferred from mutant phenotype /// 0032773 // positive regulation of monophenol monooxygenase activity // inferred from mutant phenotype /// 0032912 // negative regulation of transforming growth factor beta2 production // inferred from mutant phenotype /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042060 // wound healing // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043568 // positive regulation of insulin-like growth factor receptor signaling pathway // inferred from mutant phenotype /// 0045216 // cell-cell junction organization // traceable author statement /// 0048023 // positive regulation of melanin biosynthetic process // inferred from mutant phenotype /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051796 // negative regulation of catagen // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype /// 0060901 // regulation of hair cycle by canonical Wnt signaling pathway // inferred from mutant phenotype /// 1902910 // positive regulation of melanosome transport // inferred from mutant phenotype","0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000233 // Cadherin, cytoplasmic domain // 3.0E-52 /// IPR000233 // Cadherin, cytoplasmic domain // 5.3E-17 /// IPR002126 // Cadherin // 1.7E-16 /// IPR002126 // Cadherin // 2.0E-23 /// IPR002126 // Cadherin // 8.9E-22 /// IPR002126 // Cadherin // 1.8E-21 /// IPR002126 // Cadherin // 1.6E-16 /// IPR002126 // Cadherin // 1.8E-23 /// IPR002126 // Cadherin // 8.3E-22 /// IPR002126 // Cadherin // 1.6E-21"
"203349_s_at",1.629193543,1.513970891,1.064965515,"UP","NM_004454","chr3:185764109-185826877 (-) // 93.24 // q27.2","ets variant 5","ETV5","ENSG00000244405 /// OTTHUMG00000156639","2119","601600","NP_004445","NM_004454","0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0007274 // neuromuscular synaptic transmission // inferred from electronic annotation /// 0007610 // behavior // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0030154 // cell differentiation // not recorded /// 0034599 // cellular response to oxidative stress // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048133 // male germ-line stem cell division // inferred from electronic annotation /// 0050807 // regulation of synapse organization // inferred from electronic annotation /// 0060252 // positive regulation of glial cell proliferation // inferred from electronic annotation /// 0060762 // regulation of branching involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0071340 // skeletal muscle acetylcholine-gated channel clustering // inferred from electronic annotation","0005634 // nucleus // inferred from direct assay","0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from mutant phenotype /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001228 // RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay","---","IPR000418 // Ets domain // 3.1E-41 /// IPR006715 // PEA3-type ETS-domain transcription factor, N-terminal // 7.3E-156"
"203355_s_at",2.014338727,2.158873051,1.997012281,"UP","NM_015310","chr8:18388210-18725320 (-) // 98.57 // p22","pleckstrin and Sec7 domain containing 3","PSD3","ENSG00000156011 /// OTTHUMG00000163711","23362","614440","NP_056125 /// NP_996792 /// XP_005273518 /// XP_006716381 /// XP_006716382 /// XP_006716383 /// XP_006716384 /// XP_006716385","NM_015310 /// NM_206909 /// XM_005273461 /// XM_006716318 /// XM_006716319 /// XM_006716320 /// XM_006716321 /// XM_006716322","0016192 // vesicle-mediated transport // not recorded /// 0030182 // neuron differentiation // not recorded /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // --- /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation","0005802 // trans-Golgi network // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // not recorded /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation","0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005543 // phospholipid binding // inferred from electronic annotation","Proteasome_Degradation // GenMAPP","IPR000904 // Sec7 domain // 8.0E-54 /// IPR000904 // Sec7 domain // 2.2E-54 /// IPR000904 // Sec7 domain // 7.2E-54 /// IPR000904 // Sec7 domain // 4.3E-52 /// IPR001849 // Pleckstrin homology domain // 2.8E-16 /// IPR001849 // Pleckstrin homology domain // 9.5E-17 /// IPR001849 // Pleckstrin homology domain // 2.7E-17 /// IPR001849 // Pleckstrin homology domain // 2.5E-16 /// IPR001849 // Pleckstrin homology domain // 2.8E-16"
"203382_s_at",2.341215705,2.120499364,1.293179631,"UP","NM_000041","chr19:45409061-45412649 (+) // 99.91 // q13.32","apolipoprotein E","APOE","ENSG00000130203 /// OTTHUMG00000128901","348","104310 /// 107741 /// 269600 /// 603075 /// 606889 /// 611771","NP_000032 /// XP_005258924","NM_000041 /// XM_005258867","0000302 // response to reactive oxygen species // non-traceable author statement /// 0001523 // retinoid metabolic process // traceable author statement /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0002021 // response to dietary excess // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from direct assay /// 0006641 // triglyceride metabolic process // inferred from mutant phenotype /// 0006707 // cholesterol catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007010 // cytoskeleton organization // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007263 // nitric oxide mediated signal transduction // inferred from direct assay /// 0007271 // synaptic transmission, cholinergic // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from direct assay /// 0008203 // cholesterol metabolic process // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010544 // negative regulation of platelet activation // inferred from direct assay /// 0010873 // positive regulation of cholesterol esterification // inferred from direct assay /// 0010875 // positive regulation of cholesterol efflux // inferred from direct assay /// 0010875 // positive regulation of cholesterol efflux // inferred from genetic interaction /// 0014012 // peripheral nervous system axon regeneration // inferred from electronic annotation /// 0015909 // long-chain fatty acid transport // inferred from direct assay /// 0017038 // protein import // inferred from direct assay /// 0019934 // cGMP-mediated signaling // inferred from direct assay /// 0030195 // negative regulation of blood coagulation // inferred from direct assay /// 0030516 // regulation of axon extension // traceable author statement /// 0030828 // positive regulation of cGMP biosynthetic process // inferred from direct assay /// 0032489 // regulation of Cdc42 protein signal transduction // inferred from direct assay /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032805 // positive regulation of low-density lipoprotein particle receptor catabolic process // inferred from direct assay /// 0032868 // response to insulin // inferred from electronic annotation /// 0033344 // cholesterol efflux // inferred from direct assay /// 0033700 // phospholipid efflux // inferred from direct assay /// 0034372 // very-low-density lipoprotein particle remodeling // inferred from direct assay /// 0034372 // very-low-density lipoprotein particle remodeling // inferred from genetic interaction /// 0034374 // low-density lipoprotein particle remodeling // inferred from electronic annotation /// 0034375 // high-density lipoprotein particle remodeling // inferred from genetic interaction /// 0034380 // high-density lipoprotein particle assembly // inferred from direct assay /// 0034382 // chylomicron remnant clearance // inferred from mutant phenotype /// 0034384 // high-density lipoprotein particle clearance // inferred from direct assay /// 0034447 // very-low-density lipoprotein particle clearance // inferred from direct assay /// 0034447 // very-low-density lipoprotein particle clearance // inferred from mutant phenotype /// 0042157 // lipoprotein metabolic process // traceable author statement /// 0042158 // lipoprotein biosynthetic process // inferred from electronic annotation /// 0042159 // lipoprotein catabolic process // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043407 // negative regulation of MAP kinase activity // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043691 // reverse cholesterol transport // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045541 // negative regulation of cholesterol biosynthetic process // inferred from direct assay /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0046889 // positive regulation of lipid biosynthetic process // inferred from direct assay /// 0046907 // intracellular transport // traceable author statement /// 0048168 // regulation of neuronal synaptic plasticity // traceable author statement /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0048844 // artery morphogenesis // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred by curator /// 0051000 // positive regulation of nitric-oxide synthase activity // inferred from direct assay /// 0051044 // positive regulation of membrane protein ectodomain proteolysis // inferred from direct assay /// 0051055 // negative regulation of lipid biosynthetic process // inferred from direct assay /// 0051651 // maintenance of location in cell // inferred from electronic annotation /// 0055088 // lipid homeostasis // inferred from electronic annotation /// 0055089 // fatty acid homeostasis // inferred from direct assay /// 0060999 // positive regulation of dendritic spine development // inferred from direct assay /// 0061000 // negative regulation of dendritic spine development // inferred from direct assay /// 0071347 // cellular response to interleukin-1 // inferred from electronic annotation /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071397 // cellular response to cholesterol // inferred from electronic annotation /// 0072358 // cardiovascular system development // inferred from electronic annotation /// 0090370 // negative regulation of cholesterol efflux // inferred from direct assay /// 0097113 // alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering // inferred from direct assay /// 0097114 // N-methyl-D-aspartate receptor clustering // inferred from direct assay /// 1900221 // regulation of beta-amyloid clearance // inferred from direct assay /// 1901214 // regulation of neuron death // inferred from direct assay /// 1901215 // negative regulation of neuron death // inferred from direct assay /// 1901216 // positive regulation of neuron death // inferred from direct assay /// 1901627 // negative regulation of postsynaptic membrane organization // inferred from direct assay /// 1901628 // positive regulation of postsynaptic membrane organization // inferred from direct assay /// 1901630 // negative regulation of presynaptic membrane organization // inferred from direct assay /// 1901631 // positive regulation of presynaptic membrane organization // inferred from direct assay /// 1902004 // positive regulation of beta-amyloid formation // inferred from direct assay /// 1902430 // negative regulation of beta-amyloid formation // inferred from direct assay /// 1902947 // regulation of tau-protein kinase activity // inferred from direct assay /// 1902951 // negative regulation of dendritic spine maintenance // inferred from direct assay /// 1902952 // positive regulation of dendritic spine maintenance // inferred from direct assay /// 1902995 // positive regulation of phospholipid efflux // inferred from direct assay /// 1902998 // positive regulation of neurofibrillary tangle assembly // inferred from direct assay /// 1902999 // negative regulation of phospholipid efflux // inferred from direct assay /// 1903001 // negative regulation of lipid transport across blood brain barrier // inferred from direct assay /// 1903002 // positive regulation of lipid transport across blood brain barrier // inferred from direct assay","0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005769 // early endosome // traceable author statement /// 0005770 // late endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030425 // dendrite // non-traceable author statement /// 0031232 // extrinsic component of external side of plasma membrane // inferred from electronic annotation /// 0034361 // very-low-density lipoprotein particle // inferred from direct assay /// 0034362 // low-density lipoprotein particle // inferred from direct assay /// 0034363 // intermediate-density lipoprotein particle // inferred from direct assay /// 0034364 // high-density lipoprotein particle // inferred from direct assay /// 0042627 // chylomicron // inferred from direct assay /// 0043025 // neuronal cell body // non-traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay","0001540 // beta-amyloid binding // inferred from direct assay /// 0005319 // lipid transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0008289 // lipid binding // inferred from direct assay /// 0016209 // antioxidant activity // inferred from direct assay /// 0017127 // cholesterol transporter activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046848 // hydroxyapatite binding // inferred from electronic annotation /// 0046911 // metal chelating activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0048156 // tau protein binding // inferred from physical interaction /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay /// 0050750 // low-density lipoprotein particle receptor binding // inferred from physical interaction /// 0060228 // phosphatidylcholine-sterol O-acyltransferase activator activity // inferred from direct assay /// 0070326 // very-low-density lipoprotein particle receptor binding // inferred from direct assay /// 0070326 // very-low-density lipoprotein particle receptor binding // inferred from physical interaction /// 0071813 // lipoprotein particle binding // inferred from electronic annotation","Statin_Pathway_PharmGKB // GenMAPP","IPR000074 // Apolipoprotein A1/A4/E // 5.3E-64"
"203386_at",-1.233629371,-1.48692881,-1.380649871,"DOWN","AI650848","chr13:75858811-76056250 (-) // 98.61 // q22.2","TBC1 domain family, member 4","TBC1D4","ENSG00000136111 /// OTTHUMG00000017088","9882","612465","NP_001273587 /// NP_001273588 /// NP_055647 /// XP_005266660 /// XP_005266662 /// XP_006719965 /// XP_006719966","NM_001286658 /// NM_001286659 /// NM_014832 /// XM_005266603 /// XM_005266605 /// XM_006719902 /// XM_006719903","0016192 // vesicle-mediated transport // inferred from mutant phenotype /// 0031339 // negative regulation of vesicle fusion // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement","0005737 // cytoplasm // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0031988 // membrane-bounded vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation","---","IPR000195 // Rab-GTPase-TBC domain // 5.7E-54 /// IPR000195 // Rab-GTPase-TBC domain // 5.7E-54 /// IPR000195 // Rab-GTPase-TBC domain // 5.4E-54 /// IPR006020 // PTB/PI domain // 1.6E-9 /// IPR006020 // PTB/PI domain // 5.2E-12 /// IPR006020 // PTB/PI domain // 1.5E-9 /// IPR006020 // PTB/PI domain // 4.9E-12 /// IPR021785 // Protein of unknown function DUF3350 // 7.0E-30 /// IPR021785 // Protein of unknown function DUF3350 // 6.9E-30 /// IPR021785 // Protein of unknown function DUF3350 // 6.6E-30"
"203387_s_at",-1.584929078,-1.663754871,-1.646306992,"DOWN","NM_014832","chr13:75859252-76056250 (-) // 99.05 // q22.2","TBC1 domain family, member 4","TBC1D4","ENSG00000136111 /// OTTHUMG00000017088","9882","612465","NP_001273587 /// NP_001273588 /// NP_055647 /// XP_005266660 /// XP_005266662 /// XP_006719965 /// XP_006719966","NM_001286658 /// NM_001286659 /// NM_014832 /// XM_005266603 /// XM_005266605 /// XM_006719902 /// XM_006719903","0016192 // vesicle-mediated transport // inferred from mutant phenotype /// 0031339 // negative regulation of vesicle fusion // inferred from electronic annotation /// 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement","0005737 // cytoplasm // inferred from direct assay /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0031988 // membrane-bounded vesicle // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation","---","IPR000195 // Rab-GTPase-TBC domain // 5.7E-54 /// IPR000195 // Rab-GTPase-TBC domain // 5.7E-54 /// IPR000195 // Rab-GTPase-TBC domain // 5.4E-54 /// IPR006020 // PTB/PI domain // 1.6E-9 /// IPR006020 // PTB/PI domain // 5.2E-12 /// IPR006020 // PTB/PI domain // 1.5E-9 /// IPR006020 // PTB/PI domain // 4.9E-12 /// IPR021785 // Protein of unknown function DUF3350 // 7.0E-30 /// IPR021785 // Protein of unknown function DUF3350 // 6.9E-30 /// IPR021785 // Protein of unknown function DUF3350 // 6.6E-30"
"203409_at",1.346080505,1.223619256,1.463846463,"UP","NM_000107","chr11:47236512-47260763 (+) // 99.89 // p11.2","damage-specific DNA binding protein 2, 48kDa","DDB2","ENSG00000134574","1643","278740 /// 600811","NP_000098 /// XP_005252865 /// XP_006718224","NM_000107 /// XM_005252808 /// XM_006718161 /// XR_242780","0000209 // protein polyubiquitination // inferred from direct assay /// 0000718 // nucleotide-excision repair, DNA damage removal // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006290 // pyrimidine dimer repair // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0009411 // response to UV // inferred from direct assay /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0035518 // histone H2A monoubiquitination // inferred from direct assay /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0070914 // UV-damage excision repair // inferred from direct assay","0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0031465 // Cul4B-RING E3 ubiquitin ligase complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay","0003677 // DNA binding // traceable author statement /// 0003684 // damaged DNA binding // inferred from direct assay /// 0004842 // ubiquitin-protein transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction","---","IPR001680 // WD40 repeat // 2.9E-6 /// IPR001680 // WD40 repeat // 8.1E-11 /// IPR001680 // WD40 repeat // 5.7E-6 /// IPR001680 // WD40 repeat // 1.4E-6"
"203413_at",1.693340891,1.778661706,1.489245205,"UP","NM_006159","chr12:44902064-45270138 (-) // 99.87 // q12","NEL-like 2 (chicken)","NELL2","ENSG00000184613 /// OTTHUMG00000169464","4753","602320","NP_001138579 /// NP_001138580 /// NP_001138581 /// NP_001138582 /// NP_006150 /// XP_005268962","NM_001145107 /// NM_001145108 /// NM_001145109 /// NM_001145110 /// NM_006159 /// XM_005268905","0007155 // cell adhesion // non-traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation","0005576 // extracellular region // inferred from electronic annotation","0005198 // structural molecule activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation","---","IPR001007 // von Willebrand factor, type C // 1.5E-13 /// IPR001007 // von Willebrand factor, type C // 1.5E-12 /// IPR001007 // von Willebrand factor, type C // 1.4E-13 /// IPR001007 // von Willebrand factor, type C // 1.4E-12 /// IPR001007 // von Willebrand factor, type C // 1.5E-13 /// IPR001007 // von Willebrand factor, type C // 1.5E-12 /// IPR001791 // Laminin G domain // 6.0E-12 /// IPR001791 // Laminin G domain // 5.5E-12 /// IPR001791 // Laminin G domain // 6.0E-12 /// IPR001881 // EGF-like calcium-binding domain // 5.1E-15 /// IPR001881 // EGF-like calcium-binding domain // 6.0E-13 /// IPR001881 // EGF-like calcium-binding domain // 5.7E-11 /// IPR001881 // EGF-like calcium-binding domain // 1.4E-11 /// IPR001881 // EGF-like calcium-binding domain // 4.7E-15 /// IPR001881 // EGF-like calcium-binding domain // 5.6E-13 /// IPR001881 // EGF-like calcium-binding domain // 1.3E-11 /// IPR001881 // EGF-like calcium-binding domain // 5.1E-15 /// IPR001881 // EGF-like calcium-binding domain // 5.9E-13 /// IPR001881 // EGF-like calcium-binding domain // 5.7E-11 /// IPR001881 // EGF-like calcium-binding domain // 1.4E-11"
"203440_at",2.520135335,1.616519987,1.534984721,"UP","M34064","chr18:25530933-25591878 (-) // 98.03 // q12.1","cadherin 2, type 1, N-cadherin (neuronal)","CDH2","ENSG00000170558 /// OTTHUMG00000059940","1000","114020","NP_001783 /// XP_005258238 /// XP_005258239","NM_001792 /// XM_005258181 /// XM_005258182","0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007157 // heterophilic cell-cell adhesion // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042692 // muscle cell differentiation // traceable author statement /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0048514 // blood vessel morphogenesis // inferred from electronic annotation /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation","0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005916 // fascia adherens // inferred from electronic annotation /// 0014704 // intercalated disc // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016342 // catenin complex // inferred from direct assay /// 0030027 // lamellipodium // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // traceable author statement /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0045294 // alpha-catenin binding // inferred from physical interaction /// 0045295 // gamma-catenin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000233 // Cadherin, cytoplasmic domain // 1.5E-58 /// IPR002126 // Cadherin // 1.1E-16 /// IPR002126 // Cadherin // 4.5E-26 /// IPR002126 // Cadherin // 5.4E-23 /// IPR002126 // Cadherin // 5.4E-22 /// IPR002126 // Cadherin // 1.6E-11 /// IPR014868 // Cadherin prodomain // 4.0E-35"
"203474_at",-1.504882029,-1.479389324,-1.775219748,"DOWN","NM_006633","chr5:75699148-76003955 (+) // 99.29 // q13.3","IQ motif containing GTPase activating protein 2","IQGAP2","ENSG00000145703 /// OTTHUMG00000162432","10788","605401","NP_001272389 /// NP_001272390 /// NP_001272391 /// NP_006624 /// XP_005248466 /// XP_005248467 /// XP_005248468 /// XP_005248470 /// XP_005248471 /// XP_006714585","NM_001285460 /// NM_001285461 /// NM_001285462 /// NM_006633 /// XM_005248409 /// XM_005248410 /// XM_005248411 /// XM_005248413 /// XM_005248414 /// XM_006714522","0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0032320 // positive regulation of Ras GTPase activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation","0005622 // intracellular // inferred from electronic annotation /// 0005874 // microtubule // inferred from direct assay /// 0005902 // microvillus // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0003779 // actin binding // traceable author statement /// 0005095 // GTPase inhibitor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005099 // Ras GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005547 // phosphatidylinositol-3,4,5-trisphosphate binding // inferred from direct assay","G13_Signaling_Pathway // GenMAPP","IPR000048 // IQ motif, EF-hand binding site // 4.4E-8 /// IPR000048 // IQ motif, EF-hand binding site // 5.8E-7 /// IPR000048 // IQ motif, EF-hand binding site // 2.8E-7 /// IPR000048 // IQ motif, EF-hand binding site // 4.7E-5 /// IPR000593 // RasGAP protein, C-terminal // 3.2E-45 /// IPR000593 // RasGAP protein, C-terminal // 1.5E-45 /// IPR001715 // Calponin homology domain // 1.6E-14 /// IPR001936 // Ras GTPase-activating protein // 3.4E-52 /// IPR001936 // Ras GTPase-activating protein // 1.4E-52"
"203510_at",1.835029566,1.904814053,1.80713509,"UP","BG170541","chr7:116312458-116438433 (+) // 94.92 // q31.2","MET proto-oncogene, receptor tyrosine kinase","MET","ENSG00000105976 /// OTTHUMG00000023299","4233","114550 /// 164860 /// 605074","NP_000236 /// NP_001120972 /// XP_006716051 /// XP_006716052 /// XP_006716053 /// XP_006716054","NM_000245 /// NM_001127500 /// XM_006715988 /// XM_006715989 /// XM_006715990 /// XM_006715991","0000187 // activation of MAPK activity // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007517 // muscle organ development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010828 // positive regulation of glucose transport // inferred from electronic annotation /// 0014812 // muscle cell migration // inferred from electronic annotation /// 0014902 // myotube differentiation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // non-traceable author statement /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0030534 // adult behavior // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0048012 // hepatocyte growth factor receptor signaling pathway // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from mutant phenotype /// 0050918 // positive chemotaxis // inferred from direct assay /// 0051450 // myoblast proliferation // inferred from electronic annotation /// 0060665 // regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling // inferred from electronic annotation /// 0071526 // semaphorin-plexin signaling pathway // inferred from direct assay /// 1901299 // negative regulation of hydrogen peroxide-mediated programmed cell death // inferred from mutant phenotype /// 2001028 // positive regulation of endothelial cell chemotaxis // inferred from mutant phenotype","0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009925 // basal plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement","0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // non-traceable author statement /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005008 // hepatocyte growth factor-activated receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019903 // protein phosphatase binding // inferred from physical interaction","---","IPR000719 // Protein kinase domain // 4.0E-46 /// IPR001245 // Serine-threonine/tyrosine-protein kinase catalytic domain // 1.9E-96 /// IPR001627 // Sema domain // 5.1E-110 /// IPR002165 // Plexin // 1.6E-10 /// IPR002909 // IPT domain // 2.4E-16 /// IPR002909 // IPT domain // 3.7E-17 /// IPR002909 // IPT domain // 1.2E-10"
"203638_s_at",-2.132674265,-1.116756449,-1.208096214,"DOWN","NM_022969","chr10:123237855-123357917 (-) // 97.62 // q26.13","fibroblast growth factor receptor 2","FGFR2","ENSG00000066468 /// OTTHUMG00000019175","2263","101200 /// 101400 /// 101600 /// 123150 /// 123500 /// 123790 /// 149730 /// 176943 /// 207410 /// 609579 /// 613659 /// 614592","NP_000132 /// NP_001138385 /// NP_001138386 /// NP_001138387 /// NP_001138388 /// NP_001138389 /// NP_001138390 /// NP_001138391 /// NP_075259 /// NP_075418 /// XP_006717771 /// XP_006717772 /// XP_006717773 /// XP_006717774 /// XP_006717775 /// XP_006717776","NM_000141 /// NM_001144913 /// NM_001144914 /// NM_001144915 /// NM_001144916 /// NM_001144917 /// NM_001144918 /// NM_001144919 /// NM_022970 /// NM_022971 /// NM_022972 /// NM_022973 /// NM_022974 /// NM_022975 /// NM_022976 /// NM_023028 /// NM_023029 /// NM_023030 /// NR_073009 /// XM_006717708 /// XM_006717709 /// XM_006717710 /// XM_006717711 /// XM_006717712 /// XM_006717713","0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001657 // ureteric bud development // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0003148 // outflow tract septum morphogenesis // inferred from sequence or structural similarity /// 0003149 // membranous septum morphogenesis // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // inferred from sequence or structural similarity /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008589 // regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0009791 // post-embryonic development // inferred from sequence or structural similarity /// 0009880 // embryonic pattern specification // inferred from sequence or structural similarity /// 0009887 // organ morphogenesis // inferred from sequence or structural similarity /// 0010453 // regulation of cell fate commitment // inferred from sequence or structural similarity /// 0010518 // positive regulation of phospholipase activity // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from sequence or structural similarity /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021769 // orbitofrontal cortex development // inferred from sequence or structural similarity /// 0021847 // ventricular zone neuroblast division // inferred from sequence or structural similarity /// 0021860 // pyramidal neuron development // inferred from sequence or structural similarity /// 0022612 // gland morphogenesis // inferred from sequence or structural similarity /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030282 // bone mineralization // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from sequence or structural similarity /// 0030901 // midbrain development // inferred from sequence or structural similarity /// 0030916 // otic vesicle formation // inferred from sequence or structural similarity /// 0031069 // hair follicle morphogenesis // inferred from sequence or structural similarity /// 0032808 // lacrimal gland development // inferred from sequence or structural similarity /// 0033688 // regulation of osteoblast proliferation // traceable author statement /// 0035264 // multicellular organism growth // inferred from sequence or structural similarity /// 0035265 // organ growth // inferred from sequence or structural similarity /// 0035602 // fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow // inferred from sequence or structural similarity /// 0035603 // fibroblast growth factor receptor signaling pathway involved in hemopoiesis // inferred from sequence or structural similarity /// 0035604 // fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow // inferred from sequence or structural similarity /// 0035607 // fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0040014 // regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040036 // regulation of fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0042476 // odontogenesis // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045667 // regulation of osteoblast differentiation // traceable author statement /// 0045787 // positive regulation of cell cycle // inferred from sequence or structural similarity /// 0045839 // negative regulation of mitosis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048286 // lung alveolus development // inferred from sequence or structural similarity /// 0048333 // mesodermal cell differentiation // inferred from electronic annotation /// 0048489 // synaptic vesicle transport // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from sequence or structural similarity /// 0048562 // embryonic organ morphogenesis // inferred from sequence or structural similarity /// 0048565 // digestive tract development // inferred from sequence or structural similarity /// 0048568 // embryonic organ development // inferred from sequence or structural similarity /// 0048608 // reproductive structure development // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from mutant phenotype /// 0048705 // skeletal system morphogenesis // traceable author statement /// 0048730 // epidermis morphogenesis // inferred from sequence or structural similarity /// 0048755 // branching morphogenesis of a nerve // inferred from sequence or structural similarity /// 0048762 // mesenchymal cell differentiation // inferred from sequence or structural similarity /// 0050673 // epithelial cell proliferation // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051150 // regulation of smooth muscle cell differentiation // inferred from sequence or structural similarity /// 0051781 // positive regulation of cell division // inferred from sequence or structural similarity /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from sequence or structural similarity /// 0060348 // bone development // inferred from sequence or structural similarity /// 0060349 // bone morphogenesis // inferred from sequence or structural similarity /// 0060365 // coronal suture morphogenesis // inferred from electronic annotation /// 0060442 // branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060445 // branching involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060449 // bud elongation involved in lung branching // inferred from sequence or structural similarity /// 0060463 // lung lobe morphogenesis // inferred from sequence or structural similarity /// 0060484 // lung-associated mesenchyme development // inferred from sequence or structural similarity /// 0060501 // positive regulation of epithelial cell proliferation involved in lung morphogenesis // inferred from sequence or structural similarity /// 0060512 // prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060523 // prostate epithelial cord elongation // inferred from sequence or structural similarity /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from sequence or structural similarity /// 0060529 // squamous basal epithelial stem cell differentiation involved in prostate gland acinus development // inferred from sequence or structural similarity /// 0060595 // fibroblast growth factor receptor signaling pathway involved in mammary gland specification // inferred from sequence or structural similarity /// 0060601 // lateral sprouting from an epithelium // inferred from sequence or structural similarity /// 0060615 // mammary gland bud formation // inferred from sequence or structural similarity /// 0060664 // epithelial cell proliferation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060667 // branch elongation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060670 // branching involved in labyrinthine layer morphogenesis // inferred from sequence or structural similarity /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060688 // regulation of morphogenesis of a branching structure // inferred from sequence or structural similarity /// 0060915 // mesenchymal cell differentiation involved in lung development // inferred from sequence or structural similarity /// 0060916 // mesenchymal cell proliferation involved in lung development // inferred from sequence or structural similarity /// 0061031 // endodermal digestive tract morphogenesis // inferred from electronic annotation /// 0070307 // lens fiber cell development // inferred from electronic annotation /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity","0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0060076 // excitatory synapse // inferred from sequence or structural similarity","0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // non-traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from direct assay /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from genetic interaction /// 0005007 // fibroblast growth factor-activated receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction","---","IPR000719 // Protein kinase domain // 7.1E-52 /// IPR000719 // Protein kinase domain // 2.8E-52 /// IPR000719 // Protein kinase domain // 5.2E-52 /// IPR000719 // Protein kinase domain // 5.2E-52 /// IPR001245 // Serine-threonine/tyrosine-protein kinase catalytic domain // 3.4E-107 /// IPR001245 // Serine-threonine/tyrosine-protein kinase catalytic domain // 1.3E-107 /// IPR001245 // Serine-threonine/tyrosine-protein kinase catalytic domain // 2.5E-107 /// IPR001245 // Serine-threonine/tyrosine-protein kinase catalytic domain // 2.5E-107 /// IPR013098 // Immunoglobulin I-set // 2.6E-18 /// IPR013098 // Immunoglobulin I-set // 7.6E-15 /// IPR013098 // Immunoglobulin I-set // 3.8E-15 /// IPR013098 // Immunoglobulin I-set // 2.1E-18 /// IPR013098 // Immunoglobulin I-set // 6.1E-15 /// IPR013098 // Immunoglobulin I-set // 2.2E-18 /// IPR013151 // Immunoglobulin // 3.3E-12 /// IPR013151 // Immunoglobulin // 3.8E-8 /// IPR013151 // Immunoglobulin // 2.0E-8 /// IPR013151 // Immunoglobulin // 2.7E-12 /// IPR013151 // Immunoglobulin // 3.1E-8 /// IPR013151 // Immunoglobulin // 2.7E-12"
"203685_at",-2.112458025,-1.54795709,-1.245647819,"DOWN","NM_000633","chr18:60790578-60985930 (-) // 96.58 // q21.33","B-cell CLL/lymphoma 2","BCL2","ENSG00000171791 /// OTTHUMG00000132791","596","151430","NP_000624 /// NP_000648 /// XP_006722586","NM_000633 /// NM_000657 /// XM_006722523 /// XR_430082","0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0000209 // protein polyubiquitination // inferred from direct assay /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001101 // response to acid // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001656 // metanephros development // inferred from electronic annotation /// 0001657 // ureteric bud development // inferred from electronic annotation /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from electronic annotation /// 0001662 // behavioral fear response // inferred from electronic annotation /// 0001776 // leukocyte homeostasis // inferred from electronic annotation /// 0001782 // B cell homeostasis // inferred from electronic annotation /// 0001822 // kidney development // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from sequence or structural similarity /// 0001836 // release of cytochrome c from mitochondria // non-traceable author statement /// 0001952 // regulation of cell-matrix adhesion // inferred from electronic annotation /// 0002260 // lymphocyte homeostasis // inferred from electronic annotation /// 0002320 // lymphoid progenitor cell differentiation // inferred from electronic annotation /// 0002326 // B cell lineage commitment // inferred from electronic annotation /// 0002360 // T cell lineage commitment // inferred from electronic annotation /// 0002520 // immune system development // inferred from electronic annotation /// 0002931 // response to ischemia // inferred from electronic annotation /// 0003014 // renal system process // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006582 // melanin metabolic process // inferred from electronic annotation /// 0006808 // regulation of nitrogen utilization // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006959 // humoral immune response // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007565 // female pregnancy // non-traceable author statement /// 0007569 // cell aging // inferred from electronic annotation /// 0008219 // cell death // inferred from direct assay /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // not recorded /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation /// 0008637 // apoptotic mitochondrial changes // inferred from electronic annotation /// 0009314 // response to radiation // non-traceable author statement /// 0009605 // response to external stimulus // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from direct assay /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from direct assay /// 0010224 // response to UV-B // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010507 // negative regulation of autophagy // traceable author statement /// 0010523 // negative regulation of calcium ion transport into cytosol // inferred from electronic annotation /// 0010559 // regulation of glycoprotein biosynthetic process // inferred from electronic annotation /// 0014031 // mesenchymal cell development // inferred from electronic annotation /// 0014042 // positive regulation of neuron maturation // inferred from electronic annotation /// 0014911 // positive regulation of smooth muscle cell migration // inferred from electronic annotation /// 0016049 // cell growth // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from electronic annotation /// 0021747 // cochlear nucleus development // inferred from electronic annotation /// 0022612 // gland morphogenesis // inferred from electronic annotation /// 0022898 // regulation of transmembrane transporter activity // inferred from direct assay /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030183 // B cell differentiation // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030279 // negative regulation of ossification // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from mutant phenotype /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0031103 // axon regeneration // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from electronic annotation /// 0032469 // endoplasmic reticulum calcium ion homeostasis // traceable author statement /// 0032835 // glomerulus development // inferred from electronic annotation /// 0032848 // negative regulation of cellular pH reduction // inferred from direct assay /// 0032880 // regulation of protein localization // inferred from electronic annotation /// 0033033 // negative regulation of myeloid cell apoptotic process // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from electronic annotation /// 0033689 // negative regulation of osteoblast proliferation // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from direct assay /// 0035094 // response to nicotine // inferred from direct assay /// 0035265 // organ growth // inferred from electronic annotation /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0040007 // growth // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042100 // B cell proliferation // inferred from direct assay /// 0042149 // cellular response to glucose starvation // inferred from electronic annotation /// 0042221 // response to chemical // inferred from electronic annotation /// 0042493 // response to drug // inferred from direct assay /// 0042493 // response to drug // inferred from mutant phenotype /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043029 // T cell homeostasis // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043067 // regulation of programmed cell death // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043375 // CD8-positive, alpha-beta T cell lineage commitment // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0043496 // regulation of protein homodimerization activity // inferred from direct assay /// 0043497 // regulation of protein heterodimerization activity // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from direct assay /// 0043583 // ear development // inferred from electronic annotation /// 0045069 // regulation of viral genome replication // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045636 // positive regulation of melanocyte differentiation // inferred from electronic annotation /// 0045930 // negative regulation of mitotic cell cycle // inferred from electronic annotation /// 0046671 // negative regulation of retinal cell programmed cell death // inferred from electronic annotation /// 0046902 // regulation of mitochondrial membrane permeability // inferred from sequence or structural similarity /// 0048041 // focal adhesion assembly // inferred from electronic annotation /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0048070 // regulation of developmental pigmentation // inferred from electronic annotation /// 0048087 // positive regulation of developmental pigmentation // inferred from electronic annotation /// 0048536 // spleen development // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0048546 // digestive tract morphogenesis // inferred from electronic annotation /// 0048589 // developmental growth // inferred from electronic annotation /// 0048599 // oocyte development // inferred from electronic annotation /// 0048743 // positive regulation of skeletal muscle fiber development // inferred from electronic annotation /// 0048753 // pigment granule organization // inferred from electronic annotation /// 0048873 // homeostasis of number of cells within a tissue // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0050853 // B cell receptor signaling pathway // inferred from mutant phenotype /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051402 // neuron apoptotic process // traceable author statement /// 0051607 // defense response to virus // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from sequence or structural similarity /// 0051902 // negative regulation of mitochondrial depolarization // traceable author statement /// 0051924 // regulation of calcium ion transport // inferred from direct assay /// 0055085 // transmembrane transport // inferred from direct assay /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from direct assay /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from electronic annotation /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 2000811 // negative regulation of anoikis // inferred from mutant phenotype /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from mutant phenotype /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from genetic interaction /// 2001243 // negative regulation of intrinsic apoptotic signaling pathway // inferred from direct assay /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // traceable author statement","0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0043209 // myelin sheath // inferred from electronic annotation /// 0046930 // pore complex // inferred from direct assay","0002020 // protease binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0015267 // channel activity // inferred from direct assay /// 0016248 // channel inhibitor activity // inferred from direct assay /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051434 // BH3 domain binding // inferred from physical interaction /// 0051721 // protein phosphatase 2A binding // inferred from electronic annotation","Apoptosis // GenMAPP /// Apoptosis_GenMAPP // GenMAPP /// Apoptosis_KEGG // GenMAPP","IPR003093 // Apoptosis regulator, Bcl-2 protein, BH4 // 1.3E-18 /// IPR026298 // Blc2 family // 7.9E-34"
"203699_s_at",-2.652806987,-1.930319711,-1.301299855,"DOWN","U53506","chr14:80668120-80677949 (-) // 99.05 // q31.1","deiodinase, iodothyronine, type II","DIO2","ENSG00000211448 /// OTTHUMG00000171443","1734","601413","NP_000784 /// NP_001007024 /// NP_001229431 /// NP_001229432 /// NP_054644","NM_000793 /// NM_001007023 /// NM_001242502 /// NM_001242503 /// NM_013989","0001514 // selenocysteine incorporation // non-traceable author statement /// 0006590 // thyroid hormone generation // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042403 // thyroid hormone metabolic process // inferred from direct assay /// 0042404 // thyroid hormone catabolic process // inferred from electronic annotation /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation","0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred by curator /// 0016021 // integral component of membrane // inferred from electronic annotation","0004800 // thyroxine 5'-deiodinase activity // inferred from direct assay /// 0004800 // thyroxine 5'-deiodinase activity // traceable author statement /// 0008430 // selenium binding // inferred by curator /// 0016209 // antioxidant activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction","---","IPR000643 // Iodothyronine deiodinase // 1.1E-121 /// IPR000643 // Iodothyronine deiodinase // 2.5E-48 /// IPR000643 // Iodothyronine deiodinase // 4.1E-120 /// IPR000866 // Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant // 5.6E-9"
"203700_s_at",-1.782654937,-1.297781836,-1.058497398,"DOWN","NM_013989","chr14:80663875-80678525 (-) // 95.75 // q31.1","deiodinase, iodothyronine, type II","DIO2","---","1734","601413","NP_000784 /// NP_001007024 /// NP_001229431 /// NP_001229432 /// NP_054644","NM_000793 /// NM_001007023 /// NM_001242502 /// NM_001242503 /// NM_013989","0001514 // selenocysteine incorporation // non-traceable author statement /// 0006590 // thyroid hormone generation // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042403 // thyroid hormone metabolic process // inferred from direct assay /// 0042404 // thyroid hormone catabolic process // inferred from electronic annotation /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation","0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred by curator /// 0016021 // integral component of membrane // inferred from electronic annotation","0004800 // thyroxine 5'-deiodinase activity // inferred from direct assay /// 0004800 // thyroxine 5'-deiodinase activity // traceable author statement /// 0008430 // selenium binding // inferred by curator /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction","---","---"
"203710_at",-1.411744488,-1.929816554,-1.918236799,"DOWN","NM_002222","chr3:4535135-4889081 (+) // 99.77 // p26.1","inositol 1,4,5-trisphosphate receptor, type 1","ITPR1","ENSG00000150995 /// OTTHUMG00000154996","3708","147265","NP_001093422 /// NP_001161744 /// NP_002213 /// XP_005265166 /// XP_005265167 /// XP_006713194 /// XP_006713195 /// XP_006713196 /// XP_006713197 /// XP_006713198 /// XP_006713199","NM_001099952 /// NM_001168272 /// NM_002222 /// XM_005265109 /// XM_005265110 /// XM_006713131 /// XM_006713132 /// XM_006713133 /// XM_006713134 /// XM_006713135 /// XM_006713136","0001666 // response to hypoxia // inferred from direct assay /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // non-traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048016 // inositol phosphate-mediated signaling // inferred from electronic annotation /// 0048016 // inositol phosphate-mediated signaling // inferred from sequence or structural similarity /// 0048016 // inositol phosphate-mediated signaling // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050882 // voluntary musculoskeletal movement // inferred from electronic annotation /// 0051209 // release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from sequence or structural similarity /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation","0005635 // nuclear envelope // inferred from electronic annotation /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005955 // calcineurin complex // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0031088 // platelet dense granule membrane // inferred from direct assay /// 0031094 // platelet dense tubular network // inferred from direct assay /// 0031095 // platelet dense tubular network membrane // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation","0005216 // ion channel activity // inferred from electronic annotation /// 0005218 // intracellular ligand-gated calcium channel activity // inferred from sequence or structural similarity /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // traceable author statement /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015085 // calcium ion transmembrane transporter activity // traceable author statement /// 0035091 // phosphatidylinositol binding // inferred from sequence or structural similarity","Calcium_regulation_in_cardiac_cells // GenMAPP /// G_Protein_Signaling // GenMAPP /// Smooth_muscle_contraction // GenMAPP","IPR000699 // RIH (RyR and IP3R Homology) domain // 8.2E-76 /// IPR000699 // RIH (RyR and IP3R Homology) domain // 2.7E-62 /// IPR000699 // RIH (RyR and IP3R Homology) domain // 8.2E-76 /// IPR000699 // RIH (RyR and IP3R Homology) domain // 2.7E-62 /// IPR000699 // RIH (RyR and IP3R Homology) domain // 8.3E-76 /// IPR000699 // RIH (RyR and IP3R Homology) domain // 2.8E-62 /// IPR005821 // Ion transport domain // 6.0E-16 /// IPR005821 // Ion transport domain // 6.0E-16 /// IPR005821 // Ion transport domain // 6.1E-16 /// IPR005821 // Ion transport domain // 2.0E-17 /// IPR013662 // RyR/IP3R Homology associated domain // 1.4E-35 /// IPR013662 // RyR/IP3R Homology associated domain // 1.4E-35 /// IPR013662 // RyR/IP3R Homology associated domain // 1.4E-35 /// IPR014821 // Inositol 1,4,5-trisphosphate/ryanodine receptor // 1.8E-98 /// IPR014821 // Inositol 1,4,5-trisphosphate/ryanodine receptor // 1.4E-99 /// IPR016093 // MIR motif // 8.2E-75 /// IPR016093 // MIR motif // 1.7E-75 /// IPR016093 // MIR motif // 1.8E-75 /// IPR016093 // MIR motif // 1.2E-43"
"203716_s_at",2.883294271,2.154996125,1.754311486,"UP","M80536","chr2:162849732-162929998 (-) // 98.95 // q24.2","dipeptidyl-peptidase 4","DPP4","ENSG00000197635 /// OTTHUMG00000132056","1803","102720","NP_001926 /// XP_005246428","NM_001935 /// XM_005246371","0001666 // response to hypoxia // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010716 // negative regulation of extracellular matrix disassembly // inferred from direct assay /// 0031295 // T cell costimulation // inferred from direct assay /// 0033632 // regulation of cell-cell adhesion mediated by integrin // inferred from direct assay /// 0042110 // T cell activation // inferred from direct assay /// 0043542 // endothelial cell migration // inferred from direct assay","0005576 // extracellular region // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0046581 // intercellular canaliculus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071438 // invadopodium membrane // inferred from direct assay","0002020 // protease binding // inferred from physical interaction /// 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from direct assay /// 0008239 // dipeptidyl-peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction","---","IPR001375 // Peptidase S9, prolyl oligopeptidase, catalytic domain // 2.6E-61 /// IPR002469 // Peptidase S9B, dipeptidylpeptidase IV N-terminal // 6.8E-116 /// IPR002469 // Peptidase S9B, dipeptidylpeptidase IV N-terminal // 3.5E-18"
"203717_at",3.186885433,3.399430746,3.057715466,"UP","NM_001935","chr2:162848758-162930567 (-) // 99.79 // q24.2","dipeptidyl-peptidase 4","DPP4","ENSG00000197635 /// OTTHUMG00000132056","1803","102720","NP_001926 /// XP_005246428","NM_001935 /// XM_005246371","0001666 // response to hypoxia // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010716 // negative regulation of extracellular matrix disassembly // inferred from direct assay /// 0031295 // T cell costimulation // inferred from direct assay /// 0033632 // regulation of cell-cell adhesion mediated by integrin // inferred from direct assay /// 0042110 // T cell activation // inferred from direct assay /// 0043542 // endothelial cell migration // inferred from direct assay","0005576 // extracellular region // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0046581 // intercellular canaliculus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071438 // invadopodium membrane // inferred from direct assay","0002020 // protease binding // inferred from physical interaction /// 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from direct assay /// 0008239 // dipeptidyl-peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction","---","IPR001375 // Peptidase S9, prolyl oligopeptidase, catalytic domain // 2.6E-61 /// IPR002469 // Peptidase S9B, dipeptidylpeptidase IV N-terminal // 6.8E-116 /// IPR002469 // Peptidase S9B, dipeptidylpeptidase IV N-terminal // 3.5E-18"
"203757_s_at",1.469683729,1.360743765,1.098241559,"UP","BC005008","chr19:42259506-42275777 (+) // 53.22 // q13.2","carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)","CEACAM6","ENSG00000086548 /// OTTHUMG00000151064","4680","163980","NP_002474","NM_002483","0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement","0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation","0005515 // protein binding // inferred from physical interaction","---","IPR013098 // Immunoglobulin I-set // 6.4E-11 /// IPR013098 // Immunoglobulin I-set // 1.5E-11 /// IPR013106 // Immunoglobulin V-set domain // 2.3E-25 /// IPR013151 // Immunoglobulin // 3.6E-9 /// IPR013151 // Immunoglobulin // 9.4E-12"
"203766_s_at",-1.893467908,-1.43768693,-2.551870199,"DOWN","NM_012134","chr1:201865581-201915588 (-) // 89.95 // q32.1","leiomodin 1 (smooth muscle)","LMOD1","ENSG00000163431 /// OTTHUMG00000035802","25802","602715","NP_036266","NM_012134","0006936 // muscle contraction // traceable author statement","0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // traceable author statement","0003779 // actin binding // inferred from electronic annotation /// 0005523 // tropomyosin binding // inferred from electronic annotation","---","IPR003124 // WH2 domain // 6.4E-8 /// IPR004934 // Tropomodulin // 3.2E-20"
"203779_s_at",1.624916416,1.180136986,1.365543342,"UP","NM_005797","chr11:118125393-118134987 (-) // 99.18 // q23.3","myelin protein zero-like 2","MPZL2","ENSG00000149573 /// OTTHUMG00000166967","10205","604873","NP_005788 /// NP_658911","NM_005797 /// NM_144765","0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation","0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0005515 // protein binding // inferred from physical interaction","---","IPR013106 // Immunoglobulin V-set domain // 1.3E-22"
"203780_at",1.763378955,1.80545495,1.477287277,"UP","AF275945","chr11:118124134-118134997 (-) // 99.24 // q23.3","myelin protein zero-like 2","MPZL2","ENSG00000149573 /// OTTHUMG00000166967","10205","604873","NP_005788 /// NP_658911","NM_005797 /// NM_144765","0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation","0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0005515 // protein binding // inferred from physical interaction","---","IPR013106 // Immunoglobulin V-set domain // 1.3E-22"
"203851_at",1.390153118,1.498868365,1.418984357,"UP","NM_002178","chr12:53491448-53496124 (+) // 94.96 // q13.13","insulin-like growth factor binding protein 6","IGFBP6","ENSG00000167779 /// OTTHUMG00000169773","3489","146735","NP_002169","NM_002178","0001558 // regulation of cell growth // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement","0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation /// 0031994 // insulin-like growth factor I binding // inferred from electronic annotation","Smooth_muscle_contraction // GenMAPP","IPR000716 // Thyroglobulin type-1 // 5.7E-25 /// IPR000716 // Thyroglobulin type-1 // 5.8E-25 /// IPR000867 // Insulin-like growth factor-binding protein, IGFBP // 2.4E-9"
"203854_at",1.81884134,1.718377807,1.55413536,"UP","NM_000204","chr4:110661851-110723141 (-) // 98.98 // q25","complement factor I","CFI","ENSG00000205403 /// OTTHUMG00000161109","3426","217030 /// 610984 /// 612923 /// 615439","NP_000195 /// XP_005263032 /// XP_005263033 /// XP_006714272 /// XP_006714273","NM_000204 /// XM_005262975 /// XM_005262976 /// XM_006714209 /// XM_006714210","0002376 // immune system process // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0030449 // regulation of complement activation // traceable author statement /// 0045087 // innate immune response // traceable author statement","0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR001190 // SRCR domain // 1.3E-16 /// IPR001190 // SRCR domain // 1.2E-16 /// IPR001254 // Peptidase S1 // 5.2E-65 /// IPR001254 // Peptidase S1 // 4.9E-65 /// IPR001254 // Peptidase S1 // 5.0E-65 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 2.1E-10 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 6.7E-14 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 2.0E-10 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 6.5E-14 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 6.6E-14"
"203889_at",2.31543104,2.257348747,1.420507897,"UP","NM_003020","chr15:32935785-32989298 (+) // 98.26 // q13.3","secretogranin V (7B2 protein)","SCG5","ENSG00000166922 /// OTTHUMG00000159447","6447","173120","NP_001138229 /// NP_003011 /// XP_005254652 /// XP_005254653","NM_001144757 /// NM_003020 /// XM_005254595 /// XM_005254596","0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from sequence or structural similarity /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0016486 // peptide hormone processing // inferred from sequence or structural similarity /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0046883 // regulation of hormone secretion // inferred from sequence or structural similarity","0005576 // extracellular region // inferred from electronic annotation /// 0030141 // secretory granule // inferred from sequence or structural similarity","0004857 // enzyme inhibitor activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // traceable author statement /// 0051082 // unfolded protein binding // inferred from direct assay","---","IPR007945 // Neuroendocrine 7B2 precursor // 4.1E-73 /// IPR007945 // Neuroendocrine 7B2 precursor // 2.5E-71 /// IPR007945 // Neuroendocrine 7B2 precursor // 1.5E-61"
"203908_at",-3.272668916,-2.935689408,-3.057557143,"DOWN","NM_003759","chr4:72204816-72437799 (+) // 99.3 // q13.3","solute carrier family 4 (sodium bicarbonate cotransporter), member 4","SLC4A4","ENSG00000080493 /// OTTHUMG00000129907","8671","603345 /// 604278","NP_001091954 /// NP_001128214 /// NP_003750 /// XP_005265761 /// XP_006714461 /// XP_006714462","NM_001098484 /// NM_001134742 /// NM_003759 /// XM_005265704 /// XM_006714398 /// XM_006714399","0006810 // transport // traceable author statement /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006820 // anion transport // inferred from electronic annotation /// 0015701 // bicarbonate transport // traceable author statement /// 0035725 // sodium ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement","0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005215 // transporter activity // inferred from electronic annotation /// 0005452 // inorganic anion exchanger activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008509 // anion transmembrane transporter activity // inferred from electronic annotation /// 0008510 // sodium:bicarbonate symporter activity // traceable author statement /// 0015293 // symporter activity // inferred from electronic annotation","---","IPR011531 // Bicarbonate transporter, C-terminal // 4.1E-248 /// IPR011531 // Bicarbonate transporter, C-terminal // 4.7E-248 /// IPR013769 // Band 3 cytoplasmic domain // 3.2E-103 /// IPR013769 // Band 3 cytoplasmic domain // 3.5E-103"
"203911_at",-2.357971927,-1.571712482,-1.840157891,"DOWN","NM_002885","chr1:21922714-21995799 (-) // 95.41 // p36.12","RAP1 GTPase activating protein","RAP1GAP","ENSG00000076864 /// OTTHUMG00000007513","5909","600278","NP_001139129 /// NP_001139130 /// NP_002876 /// XP_005246011 /// XP_005246012 /// XP_005246013 /// XP_006710867 /// XP_006710868 /// XP_006710869 /// XP_006710870","NM_001145657 /// NM_001145658 /// NM_002885 /// XM_005245954 /// XM_005245955 /// XM_005245956 /// XM_006710804 /// XM_006710805 /// XM_006710806 /// XM_006710807","0006184 // GTP catabolic process // non-traceable author statement /// 0007165 // signal transduction // non-traceable author statement /// 0032318 // regulation of Ras GTPase activity // inferred from direct assay /// 0032854 // positive regulation of Rap GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation","0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay","0003924 // GTPase activity // non-traceable author statement /// 0005096 // GTPase activator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017016 // Ras GTPase binding // inferred from physical interaction /// 0030695 // GTPase regulator activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046582 // Rap GTPase activator activity // inferred from direct assay","---","IPR000331 // Rap GTPase activating protein domain // 9.9E-66 /// IPR000331 // Rap GTPase activating protein domain // 6.6E-66 /// IPR000331 // Rap GTPase activating protein domain // 7.9E-66 /// IPR000331 // Rap GTPase activating protein domain // 8.3E-66 /// IPR000331 // Rap GTPase activating protein domain // 9.4E-66 /// IPR000331 // Rap GTPase activating protein domain // 8.6E-66 /// IPR000331 // Rap GTPase activating protein domain // 6.9E-66 /// IPR003109 // GoLoco motif // 9.1E-11 /// IPR003109 // GoLoco motif // 7.1E-11 /// IPR003109 // GoLoco motif // 8.0E-11 /// IPR003109 // GoLoco motif // 8.2E-11 /// IPR003109 // GoLoco motif // 3.8E-14 /// IPR003109 // GoLoco motif // 3.6E-14 /// IPR003109 // GoLoco motif // 7.3E-11 /// IPR003109 // GoLoco motif // 2.1E-15"
"203921_at",1.597650518,1.429613282,1.288324809,"UP","NM_004267","chr3:142839308-142841798 (+) // 97.45 // q24","carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2","CHST2","ENSG00000175040 /// OTTHUMG00000159351","9435","603798","NP_004258","NM_004267","0005975 // carbohydrate metabolic process // traceable author statement /// 0006044 // N-acetylglucosamine metabolic process // inferred from direct assay /// 0006790 // sulfur compound metabolic process // inferred from direct assay /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement","0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031228 // intrinsic component of Golgi membrane // non-traceable author statement","0001517 // N-acetylglucosamine 6-O-sulfotransferase activity // inferred from direct assay /// 0008146 // sulfotransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation","---","IPR000863 // Sulfotransferase domain // 1.3E-28"
"203980_at",-1.983626653,-2.738828976,-2.403384654,"DOWN","NM_001442","chr8:82390925-82395449 (-) // 99.68 // q21.13","fatty acid binding protein 4, adipocyte","FABP4","ENSG00000170323 /// OTTHUMG00000164602","2167","600434","NP_001433","NM_001442","0001816 // cytokine production // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0019433 // triglyceride catabolic process // traceable author statement /// 0042632 // cholesterol homeostasis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0050872 // white fat cell differentiation // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from electronic annotation /// 0071285 // cellular response to lithium ion // inferred from electronic annotation","0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005811 // lipid particle // traceable author statement","0005215 // transporter activity // inferred from electronic annotation /// 0005504 // fatty acid binding // traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation","---","IPR000566 // Lipocalin/cytosolic fatty-acid binding domain // 3.4E-30"
"203999_at",1.204880412,1.20726993,1.012750696,"UP","AV731490","chr12:79258566-79845782 (+) // 96.51 // q21.2","synaptotagmin I","SYT1","ENSG00000067715 /// OTTHUMG00000134326","6857","185605","NP_001129277 /// NP_001129278 /// NP_001278830 /// NP_005630 /// XP_005269170 /// XP_006719639","NM_001135805 /// NM_001135806 /// NM_001291901 /// NM_005639 /// XM_005269113 /// XM_006719576","0005513 // detection of calcium ion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0007269 // neurotransmitter secretion // traceable author statement /// 0014047 // glutamate secretion // traceable author statement /// 0016079 // synaptic vesicle exocytosis // inferred from electronic annotation /// 0017157 // regulation of exocytosis // traceable author statement /// 0017158 // regulation of calcium ion-dependent exocytosis // inferred from electronic annotation /// 0031340 // positive regulation of vesicle fusion // inferred from electronic annotation /// 0045956 // positive regulation of calcium ion-dependent exocytosis // inferred from electronic annotation /// 0048278 // vesicle docking // inferred from electronic annotation /// 0051260 // protein homooligomerization // traceable author statement /// 0051592 // response to calcium ion // inferred from electronic annotation","0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031045 // dense core granule // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042584 // chromaffin granule membrane // inferred from electronic annotation /// 0042734 // presynaptic membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043229 // intracellular organelle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0060076 // excitatory synapse // inferred from electronic annotation /// 0060201 // clathrin-sculpted acetylcholine transport vesicle membrane // traceable author statement /// 0060203 // clathrin-sculpted glutamate transport vesicle membrane // traceable author statement /// 0061202 // clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane // traceable author statement /// 0070083 // clathrin-sculpted monoamine transport vesicle membrane // traceable author statement","0000149 // SNARE binding // inferred from electronic annotation /// 0001786 // phosphatidylserine binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // traceable author statement /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation /// 0005545 // 1-phosphatidylinositol binding // traceable author statement /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0017075 // syntaxin-1 binding // traceable author statement /// 0019905 // syntaxin binding // inferred from electronic annotation /// 0030276 // clathrin binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0048306 // calcium-dependent protein binding // inferred from electronic annotation /// 0050750 // low-density lipoprotein particle receptor binding // inferred from direct assay","---","IPR000008 // C2 domain // 1.7E-29 /// IPR000008 // C2 domain // 8.9E-31 /// IPR000008 // C2 domain // 1.7E-29 /// IPR000008 // C2 domain // 8.8E-31"
"204014_at",2.815533242,1.919709107,1.016781503,"UP","NM_001394","chr8:29193619-29208041 (-) // 99.32 // p12","dual specificity phosphatase 4","DUSP4","ENSG00000120875 /// OTTHUMG00000133395","1846","602747","NP_001385 /// NP_476499","NM_001394 /// NM_057158","0000165 // MAPK cascade // traceable author statement /// 0000188 // inactivation of MAPK activity // inferred from electronic annotation /// 0001706 // endoderm formation // not recorded /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006470 // protein dephosphorylation // not recorded /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement","0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement","0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0008330 // protein tyrosine/threonine phosphatase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation","---","IPR000242 // Protein-tyrosine phosphatase, receptor/non-receptor type // 7.5E-10 /// IPR000340 // Dual specificity phosphatase, catalytic domain // 3.2E-48 /// IPR001763 // Rhodanese-like domain // 6.5E-14"
"204018_x_at",-1.324374564,-1.503172962,-1.709230364,"DOWN","NM_000558","chr16:226678-227520 (+) // 99.83 // p13.3","hemoglobin, alpha 1 /// hemoglobin, alpha 2","HBA1 /// HBA2","ENSG00000188536 /// ENSG00000206172 /// OTTHUMG00000059924 /// OTTHUMG00000060138","3039 /// 3040","140700 /// 141800 /// 141850 /// 604131 /// 613978","NP_000508 /// NP_000549","NM_000517 /// NM_000558","0006810 // transport // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0015671 // oxygen transport // traceable author statement /// 0015701 // bicarbonate transport // traceable author statement /// 0042542 // response to hydrogen peroxide // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay","0005576 // extracellular region // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005833 // hemoglobin complex // inferred from direct assay /// 0005833 // hemoglobin complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0031838 // haptoglobin-hemoglobin complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay","0004601 // peroxidase activity // inferred from direct assay /// 0005344 // oxygen transporter activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019825 // oxygen binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0031720 // haptoglobin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000971 // Globin // 2.9E-32"
"204042_at",-1.428611879,-1.421950712,-1.681050197,"DOWN","AB020707","chr13:27131887-27263067 (+) // 98.88 // q12.13","WAS protein family, member 3","WASF3","ENSG00000132970 /// OTTHUMG00000016621","10810","605068","NP_001278894 /// NP_006637 /// XP_005266296","NM_001291965 /// NM_006646 /// XM_005266239","0006461 // protein complex assembly // traceable author statement /// 0007010 // cytoskeleton organization // inferred from mutant phenotype /// 0008360 // regulation of cell shape // inferred from mutant phenotype /// 0014003 // oligodendrocyte development // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030041 // actin filament polymerization // traceable author statement /// 0031643 // positive regulation of myelination // inferred from electronic annotation","0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation","0003779 // actin binding // inferred from electronic annotation","---","IPR003124 // WH2 domain // 1.2E-10 /// IPR003124 // WH2 domain // 1.2E-10"
"204105_s_at",1.990601846,1.960841758,2.313016666,"UP","NM_005010","chr7:107788093-108096770 (-) // 99.89 // q31.1","neuronal cell adhesion molecule","NRCAM","ENSG00000091129 /// OTTHUMG00000154973","4897","601581","NP_001032209 /// NP_001180511 /// NP_001180512 /// NP_001180513 /// NP_005001 /// XP_005250430 /// XP_005250437 /// XP_005250440 /// XP_005250442 /// XP_006716066 /// XP_006716067 /// XP_006716068 /// XP_006716069 /// XP_006716070 /// XP_006716071 /// XP_006716072 /// XP_006716073 /// XP_006716074 /// XP_006716075 /// XP_006716076 /// XP_006716077","NM_001037132 /// NM_001037133 /// NM_001193582 /// NM_001193583 /// NM_001193584 /// NM_005010 /// XM_005250373 /// XM_005250380 /// XM_005250383 /// XM_005250385 /// XM_006716003 /// XM_006716004 /// XM_006716005 /// XM_006716006 /// XM_006716007 /// XM_006716008 /// XM_006716009 /// XM_006716010 /// XM_006716011 /// XM_006716012 /// XM_006716013 /// XM_006716014 /// XR_428177 /// XR_428178","0001525 // angiogenesis // inferred from expression pattern /// 0001764 // neuron migration // non-traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007409 // axonogenesis // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007413 // axonal fasciculation // non-traceable author statement /// 0007416 // synapse assembly // traceable author statement /// 0007417 // central nervous system development // non-traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0010975 // regulation of neuron projection development // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0019227 // neuronal action potential propagation // inferred from electronic annotation /// 0030516 // regulation of axon extension // non-traceable author statement /// 0031290 // retinal ganglion cell axon guidance // inferred from electronic annotation /// 0034113 // heterotypic cell-cell adhesion // inferred from electronic annotation /// 0045162 // clustering of voltage-gated sodium channels // inferred from direct assay /// 0045666 // positive regulation of neuron differentiation // non-traceable author statement","0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009897 // external side of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043005 // neuron projection // non-traceable author statement /// 0043194 // axon initial segment // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation","0005515 // protein binding // inferred from physical interaction /// 0030506 // ankyrin binding // inferred from direct assay /// 0086080 // protein binding involved in heterotypic cell-cell adhesion // inferred from electronic annotation","---","IPR003961 // Fibronectin, type III // 9.2E-18 /// IPR003961 // Fibronectin, type III // 2.8E-11 /// IPR003961 // Fibronectin, type III // 8.3E-18 /// IPR003961 // Fibronectin, type III // 1.2E-17 /// IPR003961 // Fibronectin, type III // 1.0E-17 /// IPR003961 // Fibronectin, type III // 3.1E-11 /// IPR003961 // Fibronectin, type III // 9.4E-18 /// IPR003961 // Fibronectin, type III // 1.3E-17 /// IPR003961 // Fibronectin, type III // 1.1E-10 /// IPR003961 // Fibronectin, type III // 9.1E-18 /// IPR003961 // Fibronectin, type III // 2.8E-11 /// IPR003961 // Fibronectin, type III // 8.3E-18 /// IPR003961 // Fibronectin, type III // 1.1E-17 /// IPR013098 // Immunoglobulin I-set // 5.4E-13 /// IPR013098 // Immunoglobulin I-set // 2.0E-15 /// IPR013098 // Immunoglobulin I-set // 1.3E-14 /// IPR013098 // Immunoglobulin I-set // 1.3E-15 /// IPR013098 // Immunoglobulin I-set // 2.9E-17 /// IPR013098 // Immunoglobulin I-set // 6.0E-13 /// IPR013098 // Immunoglobulin I-set // 2.3E-15 /// IPR013098 // Immunoglobulin I-set // 1.5E-14 /// IPR013098 // Immunoglobulin I-set // 1.5E-15 /// IPR013098 // Immunoglobulin I-set // 3.3E-17 /// IPR013098 // Immunoglobulin I-set // 5.3E-13 /// IPR013098 // Immunoglobulin I-set // 2.0E-15 /// IPR013098 // Immunoglobulin I-set // 1.3E-14 /// IPR013098 // Immunoglobulin I-set // 1.3E-15 /// IPR013098 // Immunoglobulin I-set // 2.9E-17 /// IPR013151 // Immunoglobulin // 1.3E-8 /// IPR013151 // Immunoglobulin // 3.6E-9 /// IPR013151 // Immunoglobulin // 2.3E-10 /// IPR013151 // Immunoglobulin // 1.4E-8 /// IPR013151 // Immunoglobulin // 4.0E-9 /// IPR013151 // Immunoglobulin // 2.6E-10 /// IPR013151 // Immunoglobulin // 1.2E-8 /// IPR013151 // Immunoglobulin // 3.6E-9 /// IPR013151 // Immunoglobulin // 2.3E-10"
"204124_at",2.661644627,3.557315853,4.153658335,"UP","AF146796","chr4:25657484-25680366 (+) // 93.62 // p15.2","solute carrier family 34 (type II sodium/phosphate contransporter), member 2","SLC34A2","ENSG00000157765 /// OTTHUMG00000097757","10568","265100 /// 604217 /// 610441","NP_001171469 /// NP_001171470 /// NP_006415","NM_001177998 /// NM_001177999 /// NM_006424","0001701 // in utero embryonic development // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006817 // phosphate ion transport // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0009750 // response to fructose // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030643 // cellular phosphate ion homeostasis // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0035435 // phosphate ion transmembrane transport // inferred from direct assay /// 0035725 // sodium ion transmembrane transport // inferred from direct assay /// 0043627 // response to estrogen // inferred from expression pattern /// 0044341 // sodium-dependent phosphate transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement","0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0005903 // brush border // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016021 // integral component of membrane // non-traceable author statement /// 0016324 // apical plasma membrane // inferred from direct assay /// 0031526 // brush border membrane // inferred from sequence or structural similarity /// 0031528 // microvillus membrane // inferred from electronic annotation","0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005436 // sodium:phosphate symporter activity // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015321 // sodium-dependent phosphate transmembrane transporter activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031402 // sodium ion binding // inferred from direct assay /// 0042301 // phosphate ion binding // inferred from direct assay /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation","---","IPR003841 // Sodium-dependent phosphate transport protein // 1.6E-34 /// IPR003841 // Sodium-dependent phosphate transport protein // 2.7E-31"
"204151_x_at",-1.642559758,-1.176425185,-1.524394968,"DOWN","NM_001353","chr10:5005631-5020157 (+) // 99.34 // p15.1 /// chr10:5031965-5046032 (-) // 97.1 // p15.1","aldo-keto reductase family 1, member C1","AKR1C1","ENSG00000187134 /// OTTHUMG00000017580","1645","600449","NP_001344","NM_001353","0001523 // retinoid metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007586 // digestion // inferred from direct assay /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // inferred from direct assay /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0015721 // bile acid and bile salt transport // traceable author statement /// 0030299 // intestinal cholesterol absorption // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from direct assay /// 0034694 // response to prostaglandin // inferred from direct assay /// 0042448 // progesterone metabolic process // inferred from direct assay /// 0042574 // retinal metabolic process // inferred from direct assay /// 0042632 // cholesterol homeostasis // traceable author statement /// 0044597 // daunorubicin metabolic process // inferred from mutant phenotype /// 0044598 // doxorubicin metabolic process // inferred from mutant phenotype /// 0046683 // response to organophosphorus // inferred from expression pattern /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0071395 // cellular response to jasmonic acid stimulus // inferred from direct assay","0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0004032 // alditol:NADP+ 1-oxidoreductase activity // inferred from direct assay /// 0004033 // aldo-keto reductase (NADP) activity // traceable author statement /// 0004958 // prostaglandin F receptor activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016655 // oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor // inferred from direct assay /// 0018636 // phenanthrene 9,10-monooxygenase activity // inferred from direct assay /// 0031406 // carboxylic acid binding // inferred from direct assay /// 0032052 // bile acid binding // inferred from direct assay /// 0047006 // 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity // inferred from electronic annotation /// 0047042 // androsterone dehydrogenase (B-specific) activity // inferred from direct assay /// 0047086 // ketosteroid monooxygenase activity // inferred from direct assay /// 0047115 // trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity // inferred from direct assay /// 0047718 // indanol dehydrogenase activity // inferred from electronic annotation","---","IPR023210 // NADP-dependent oxidoreductase domain // 1.9E-63"
"204259_at",1.570116487,1.416920082,1.911844136,"UP","NM_002423","chr11:102391238-102401478 (-) // 85.54 // q22.2","matrix metallopeptidase 7 (matrilysin, uterine)","MMP7","ENSG00000137673 /// OTTHUMG00000048193","4316","178990","NP_002414","NM_002423","0002779 // antibacterial peptide secretion // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0050829 // defense response to Gram-negative bacterium // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation","0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","Matrix_Metalloproteinases // GenMAPP","IPR001818 // Peptidase M10, metallopeptidase // 2.3E-57 /// IPR002477 // Peptidoglycan binding-like // 3.1E-16"
"204288_s_at",-2.315098825,-1.772708465,-1.082095354,"DOWN","NM_021069","chr4:186508479-186877522 (-) // 98.93 // q35.1","sorbin and SH3 domain containing 2","SORBS2","ENSG00000154556 /// OTTHUMG00000157215","8470","---","NP_001139142 /// NP_001139143 /// NP_001139144 /// NP_001139145 /// NP_001139146 /// NP_001139147 /// NP_001257700 /// NP_003594 /// NP_066547 /// XP_005263359 /// XP_005263362 /// XP_005263363 /// XP_005263364 /// XP_005263365 /// XP_005263367 /// XP_005263368 /// XP_005263369 /// XP_005263370 /// XP_006714408 /// XP_006714409 /// XP_006714410 /// XP_006714411 /// XP_006714412 /// XP_006714413 /// XP_006714414 /// XP_006714415 /// XP_006714416 /// XP_006714417 /// XP_006714418 /// XP_006714419 /// XP_006714420 /// XP_006714421 /// XP_006714422 /// XP_006714423 /// XP_006714424 /// XP_006714425 /// XP_006714426 /// XP_006714427 /// XP_006714428 /// XP_006714429 /// XP_006714430 /// XP_006714431 /// XP_006714432 /// XP_006714433 /// XP_006714434 /// XP_006714435 /// XP_006714436 /// XP_006714437 /// XP_006714438 /// XP_006714439 /// XP_006714440 /// XP_006714441 /// XP_006714442 /// XP_006714443 /// XP_006714444 /// XP_006714445 /// XP_006714446 /// XP_006714447 /// XP_006714448 /// XP_006714449 /// XP_006714450 /// XP_006714451 /// XP_006714452 /// XP_006714453","NM_001145670 /// NM_001145671 /// NM_001145672 /// NM_001145673 /// NM_001145674 /// NM_001145675 /// NM_001270771 /// NM_003603 /// NM_021069 /// XM_005263302 /// XM_005263305 /// XM_005263306 /// XM_005263307 /// XM_005263308 /// XM_005263310 /// XM_005263311 /// XM_005263312 /// XM_005263313 /// XM_006714345 /// XM_006714346 /// XM_006714347 /// XM_006714348 /// XM_006714349 /// XM_006714350 /// XM_006714351 /// XM_006714352 /// XM_006714353 /// XM_006714354 /// XM_006714355 /// XM_006714356 /// XM_006714357 /// XM_006714358 /// XM_006714359 /// XM_006714360 /// XM_006714361 /// XM_006714362 /// XM_006714363 /// XM_006714364 /// XM_006714365 /// XM_006714366 /// XM_006714367 /// XM_006714368 /// XM_006714369 /// XM_006714370 /// XM_006714371 /// XM_006714372 /// XM_006714373 /// XM_006714374 /// XM_006714375 /// XM_006714376 /// XM_006714377 /// XM_006714378 /// XM_006714379 /// XM_006714380 /// XM_006714381 /// XM_006714382 /// XM_006714383 /// XM_006714384 /// XM_006714385 /// XM_006714386 /// XM_006714387 /// XM_006714388 /// XM_006714389 /// XM_006714390","0007015 // actin filament organization // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation","0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030018 // Z disc // non-traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation","0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // traceable author statement /// 0008307 // structural constituent of muscle // traceable author statement /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR001452 // SH3 domain // 3.9E-18 /// IPR001452 // SH3 domain // 7.1E-16 /// IPR001452 // SH3 domain // 1.3E-13 /// IPR001452 // SH3 domain // 2.7E-18 /// IPR001452 // SH3 domain // 5.0E-16 /// IPR001452 // SH3 domain // 9.1E-14 /// IPR001452 // SH3 domain // 2.4E-18 /// IPR001452 // SH3 domain // 4.3E-16 /// IPR001452 // SH3 domain // 7.8E-14 /// IPR001452 // SH3 domain // 2.0E-18 /// IPR001452 // SH3 domain // 3.7E-16 /// IPR001452 // SH3 domain // 6.7E-14 /// IPR001452 // SH3 domain // 4.3E-18 /// IPR001452 // SH3 domain // 7.8E-16 /// IPR001452 // SH3 domain // 1.4E-13 /// IPR001452 // SH3 domain // 2.1E-18 /// IPR001452 // SH3 domain // 3.8E-16 /// IPR001452 // SH3 domain // 7.0E-14 /// IPR001452 // SH3 domain // 2.1E-18 /// IPR001452 // SH3 domain // 3.8E-16 /// IPR001452 // SH3 domain // 6.9E-14 /// IPR001452 // SH3 domain // 3.5E-18 /// IPR001452 // SH3 domain // 6.3E-16 /// IPR001452 // SH3 domain // 1.1E-13 /// IPR003127 // Sorbin-like // 6.5E-34 /// IPR003127 // Sorbin-like // 4.6E-34 /// IPR003127 // Sorbin-like // 4.0E-34 /// IPR003127 // Sorbin-like // 1.6E-33 /// IPR003127 // Sorbin-like // 7.2E-34 /// IPR003127 // Sorbin-like // 3.5E-34 /// IPR003127 // Sorbin-like // 3.5E-34 /// IPR003127 // Sorbin-like // 2.9E-23 /// IPR011511 // Variant SH3 domain // 3.2E-18 /// IPR011511 // Variant SH3 domain // 3.2E-9 /// IPR011511 // Variant SH3 domain // 2.5E-9 /// IPR011511 // Variant SH3 domain // 2.2E-18 /// IPR011511 // Variant SH3 domain // 2.3E-9 /// IPR011511 // Variant SH3 domain // 1.8E-9 /// IPR011511 // Variant SH3 domain // 1.9E-18 /// IPR011511 // Variant SH3 domain // 2.0E-9 /// IPR011511 // Variant SH3 domain // 1.5E-9 /// IPR011511 // Variant SH3 domain // 1.6E-18 /// IPR011511 // Variant SH3 domain // 1.7E-9 /// IPR011511 // Variant SH3 domain // 1.3E-9 /// IPR011511 // Variant SH3 domain // 3.5E-18 /// IPR011511 // Variant SH3 domain // 3.6E-9 /// IPR011511 // Variant SH3 domain // 2.8E-9 /// IPR011511 // Variant SH3 domain // 1.7E-18 /// IPR011511 // Variant SH3 domain // 1.7E-9 /// IPR011511 // Variant SH3 domain // 1.3E-9 /// IPR011511 // Variant SH3 domain // 1.7E-18 /// IPR011511 // Variant SH3 domain // 1.7E-9 /// IPR011511 // Variant SH3 domain // 1.3E-9 /// IPR011511 // Variant SH3 domain // 2.8E-18 /// IPR011511 // Variant SH3 domain // 2.9E-9 /// IPR011511 // Variant SH3 domain // 2.2E-9"
"204304_s_at",-2.752701704,-2.014825824,-1.627786873,"DOWN","NM_006017","chr4:15969856-16077566 (-) // 99.92 // p15.32","prominin 1","PROM1","ENSG00000007062 /// OTTHUMG00000160180","8842","603786 /// 604365 /// 608051 /// 612095 /// 612657","NP_001139319 /// NP_001139320 /// NP_001139321 /// NP_001139322 /// NP_001139323 /// NP_001139324 /// NP_006008 /// XP_005248252 /// XP_005248253 /// XP_006714036 /// XP_006714037","NM_001145847 /// NM_001145848 /// NM_001145849 /// NM_001145850 /// NM_001145851 /// NM_001145852 /// NM_006017 /// XM_005248195 /// XM_005248196 /// XM_006713973 /// XM_006713974","0010842 // retina layer formation // inferred from sequence or structural similarity /// 0045494 // photoreceptor cell maintenance // inferred from mutant phenotype /// 0060042 // retina morphogenesis in camera-type eye // inferred from mutant phenotype /// 0060219 // camera-type eye photoreceptor cell differentiation // inferred from mutant phenotype /// 0060219 // camera-type eye photoreceptor cell differentiation // inferred from sequence or structural similarity /// 0072112 // glomerular visceral epithelial cell differentiation // inferred from mutant phenotype /// 0072139 // glomerular parietal epithelial cell differentiation // inferred from mutant phenotype /// 2000768 // positive regulation of nephron tubule epithelial cell differentiation // inferred from mutant phenotype","0001750 // photoreceptor outer segment // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005902 // microvillus // inferred from electronic annotation /// 0005903 // brush border // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031528 // microvillus membrane // inferred from electronic annotation /// 0032420 // stereocilium // inferred from electronic annotation /// 0042622 // photoreceptor outer segment membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005515 // protein binding // inferred from physical interaction /// 0042805 // actinin binding // inferred from direct assay /// 0045296 // cadherin binding // inferred from physical interaction","---","IPR008795 // Prominin // 0.0 /// IPR008795 // Prominin // 0.0 /// IPR008795 // Prominin // 0.0"
"204328_at",1.736378366,1.715754605,1.488553615,"UP","NM_007267","chr17:76109001-76120120 (-) // 98.47 // q25.3","transmembrane channel-like 6","TMC6","ENSG00000141524 /// OTTHUMG00000177466","11322","226400 /// 605828","NP_001120670 /// NP_009198 /// XP_005257052 /// XP_005257053 /// XP_005257054 /// XP_005257055","NM_001127198 /// NM_007267 /// XM_005256995 /// XM_005256996 /// XM_005256997 /// XM_005256998 /// XR_243632","0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation","0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005515 // protein binding // inferred from physical interaction","---","IPR012496 // TMC // 3.3E-45"
"204359_at",-1.297594021,-1.29206853,-1.440636793,"DOWN","NM_013231","chr14:86087720-86094263 (+) // 86.16 // q31.3","fibronectin leucine rich transmembrane protein 2 /// uncharacterized LOC100506718","FLRT2 /// LOC100506718","ENSG00000185070 /// OTTHUMG00000171372","23768 /// 100506718","604807","NP_037363 /// XP_005267546 /// XP_005267547 /// XP_006720158","NM_013231 /// XM_005267489 /// XM_005267490 /// XM_006720095 /// XR_111450 /// XR_172052 /// XR_248023 /// XR_248024 /// XR_248025 /// XR_424524 /// XR_424525 /// XR_424526 /// XR_424527 /// XR_429303 /// XR_429304 /// XR_429305 /// XR_429306 /// XR_429307 /// XR_429308 /// XR_429309 /// XR_433009 /// XR_433010 /// XR_433011 /// XR_433012 /// XR_433013","0007155 // cell adhesion // inferred from electronic annotation /// 0035556 // intracellular signal transduction // non-traceable author statement","0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005057 // receptor signaling protein activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0030674 // protein binding, bridging // non-traceable author statement","---","IPR000372 // Leucine-rich repeat-containing N-terminal // 2.2E-8 /// IPR001611 // Leucine-rich repeat // 2.7E-5 /// IPR001611 // Leucine-rich repeat // 3.7E-5 /// IPR003961 // Fibronectin, type III // 6.5E-9"
"204401_at",1.959797434,1.859182053,2.327070948,"UP","NM_002250","chr19:44270686-44285409 (-) // 100.0 // q13.31","potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4","KCNN4","ENSG00000104783 /// OTTHUMG00000182779","3783","602754","NP_002241 /// XP_005258939 /// XP_005258940 /// XP_005258943","NM_002250 /// XM_005258882 /// XM_005258883 /// XM_005258886","0002376 // immune system process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0006816 // calcium ion transport // inferred from direct assay /// 0006820 // anion transport // inferred from electronic annotation /// 0006884 // cell volume homeostasis // inferred from electronic annotation /// 0006952 // defense response // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0030322 // stabilization of membrane potential // inferred from direct assay /// 0045332 // phospholipid translocation // inferred from electronic annotation /// 0046541 // saliva secretion // inferred from electronic annotation /// 0050714 // positive regulation of protein secretion // inferred from electronic annotation /// 0050862 // positive regulation of T cell receptor signaling pathway // inferred from direct assay /// 0071435 // potassium ion export // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // not recorded","0005886 // plasma membrane // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred by curator /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // not recorded /// 0045121 // membrane raft // inferred from electronic annotation","0005267 // potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // not recorded /// 0015269 // calcium-activated potassium channel activity // inferred from direct assay /// 0016286 // small conductance calcium-activated potassium channel activity // not recorded /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0022894 // Intermediate conductance calcium-activated potassium channel activity // not recorded","---","IPR004178 // Calmodulin-binding domain // 3.4E-34 /// IPR004178 // Calmodulin-binding domain // 1.4E-11 /// IPR013099 // Two pore domain potassium channel domain // 7.4E-19 /// IPR015449 // Potassium channel, calcium-activated, SK // 7.8E-45"
"204416_x_at",2.47335588,1.741935691,1.189171156,"UP","NM_001645","chr19:45417957-45422599 (+) // 99.28 // q13.32","apolipoprotein C-I","APOC1","---","341","107710","NP_001636 /// XP_005258912","NM_001645 /// XM_005258855","0006629 // lipid metabolic process // traceable author statement /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0010873 // positive regulation of cholesterol esterification // traceable author statement /// 0010900 // negative regulation of phosphatidylcholine catabolic process // inferred from direct assay /// 0010916 // negative regulation of very-low-density lipoprotein particle clearance // inferred from direct assay /// 0032374 // regulation of cholesterol transport // inferred by curator /// 0032375 // negative regulation of cholesterol transport // inferred from direct assay /// 0033344 // cholesterol efflux // inferred from direct assay /// 0033700 // phospholipid efflux // inferred from direct assay /// 0034369 // plasma lipoprotein particle remodeling // inferred from direct assay /// 0034375 // high-density lipoprotein particle remodeling // traceable author statement /// 0034379 // very-low-density lipoprotein particle assembly // traceable author statement /// 0034382 // chylomicron remnant clearance // inferred from direct assay /// 0034447 // very-low-density lipoprotein particle clearance // inferred from genetic interaction /// 0042157 // lipoprotein metabolic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0045717 // negative regulation of fatty acid biosynthetic process // inferred from direct assay /// 0045833 // negative regulation of lipid metabolic process // inferred from direct assay /// 0048261 // negative regulation of receptor-mediated endocytosis // inferred from direct assay /// 0050995 // negative regulation of lipid catabolic process // inferred from direct assay /// 0051005 // negative regulation of lipoprotein lipase activity // inferred from direct assay","0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0034361 // very-low-density lipoprotein particle // inferred from direct assay /// 0034364 // high-density lipoprotein particle // inferred from direct assay /// 0042627 // chylomicron // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0004859 // phospholipase inhibitor activity // inferred from direct assay /// 0005504 // fatty acid binding // inferred from direct assay /// 0031210 // phosphatidylcholine binding // traceable author statement /// 0055102 // lipase inhibitor activity // inferred from direct assay /// 0060228 // phosphatidylcholine-sterol O-acyltransferase activator activity // traceable author statement","Statin_Pathway_PharmGKB // GenMAPP","---"
"204446_s_at",3.019947882,3.000228138,2.483760344,"UP","NM_000698","chr10:45869685-45941561 (+) // 96.56 // q11.21","arachidonate 5-lipoxygenase","ALOX5","ENSG00000012779 /// OTTHUMG00000018081 /// OTTHUMG00000174846","240","152390 /// 600807","NP_000689 /// NP_001243082 /// NP_001243083","NM_000698 /// NM_001256153 /// NM_001256154","0002540 // leukotriene production involved in inflammatory response // inferred from electronic annotation /// 0006691 // leukotriene metabolic process // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019370 // leukotriene biosynthetic process // inferred from direct assay /// 0019372 // lipoxygenase pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 2001300 // lipoxin metabolic process // traceable author statement","0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005641 // nuclear envelope lumen // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay","0004051 // arachidonate 5-lipoxygenase activity // inferred from direct assay /// 0005506 // iron ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016702 // oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation","Eicosanoid_Synthesis // GenMAPP /// PWY66-375 // MetaCyc /// PWY66-392 // MetaCyc /// PWY66-393 // MetaCyc /// PWY66-394 // MetaCyc /// PWY66-395 // MetaCyc /// PWY66-397 // MetaCyc","IPR001024 // PLAT/LH2 domain // 5.3E-33 /// IPR001024 // PLAT/LH2 domain // 4.6E-33 /// IPR013819 // Lipoxygenase, C-terminal // 3.7E-180 /// IPR013819 // Lipoxygenase, C-terminal // 5.9E-146 /// IPR013819 // Lipoxygenase, C-terminal // 4.3E-11"
"204513_s_at",-2.186914646,-2.152565617,-2.029717321,"DOWN","NM_014800","chr7:36893966-37025697 (-) // 98.81 // p14.2","engulfment and cell motility 1","ELMO1","ENSG00000155849 /// OTTHUMG00000023701","9844","606420","NP_001034548 /// NP_001193409 /// NP_001193411 /// NP_055615 /// NP_569709 /// XP_005249976 /// XP_005249977 /// XP_006715868","NM_001039459 /// NM_001206480 /// NM_001206482 /// NM_014800 /// NM_130442 /// NR_038120 /// XM_005249919 /// XM_005249920 /// XM_006715805","0006909 // phagocytosis // inferred from electronic annotation /// 0006911 // phagocytosis, engulfment // inferred from genetic interaction /// 0006915 // apoptotic process // non-traceable author statement /// 0006928 // cellular component movement // inferred from genetic interaction /// 0016032 // viral process // traceable author statement /// 0016601 // Rac protein signal transduction // inferred from genetic interaction /// 0030029 // actin filament-based process // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from genetic interaction /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050690 // regulation of defense response to virus by virus // traceable author statement","0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation","0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction","---","IPR006816 // Engulfment/cell motility, ELMO // 1.4E-53 /// IPR024574 // Domain of unknown function DUF3361 // 1.9E-75"
"204606_at",-3.505637633,-1.594818482,-2.060762731,"DOWN","NM_002989","chr9:34709003-34710121 (-) // 99.65 // p13.3","chemokine (C-C motif) ligand 21","CCL21","ENSG00000137077 /// OTTHUMG00000019838","6366","602737","NP_002980","NM_002989","0001768 // establishment of T cell polarity // inferred from direct assay /// 0001771 // immunological synapse formation // inferred from sequence or structural similarity /// 0001954 // positive regulation of cell-matrix adhesion // inferred from direct assay /// 0002407 // dendritic cell chemotaxis // inferred from direct assay /// 0002606 // positive regulation of dendritic cell antigen processing and presentation // inferred from sequence or structural similarity /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // non-traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0010560 // positive regulation of glycoprotein biosynthetic process // inferred from sequence or structural similarity /// 0030838 // positive regulation of actin filament polymerization // inferred from direct assay /// 0031274 // positive regulation of pseudopodium assembly // inferred from direct assay /// 0031295 // T cell costimulation // inferred from sequence or structural similarity /// 0031529 // ruffle organization // inferred from direct assay /// 0032862 // activation of Rho GTPase activity // inferred from direct assay /// 0033630 // positive regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0034695 // response to prostaglandin E // inferred from direct assay /// 0035759 // mesangial cell-matrix adhesion // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0048260 // positive regulation of receptor-mediated endocytosis // inferred from sequence or structural similarity /// 0048469 // cell maturation // inferred from sequence or structural similarity /// 0050921 // positive regulation of chemotaxis // inferred from sequence or structural similarity /// 0051209 // release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051491 // positive regulation of filopodium assembly // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0090023 // positive regulation of neutrophil chemotaxis // inferred from direct assay /// 0097026 // dendritic cell dendrite assembly // inferred from sequence or structural similarity /// 2000107 // negative regulation of leukocyte apoptotic process // inferred from direct assay /// 2000147 // positive regulation of cell motility // inferred from direct assay /// 2000406 // positive regulation of T cell migration // inferred from direct assay /// 2000529 // positive regulation of myeloid dendritic cell chemotaxis // inferred from direct assay /// 2000548 // negative regulation of dendritic cell dendrite assembly // inferred from sequence or structural similarity","0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay","0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from direct assay /// 0031732 // CCR7 chemokine receptor binding // inferred from sequence or structural similarity /// 0042379 // chemokine receptor binding // inferred from direct assay","---","IPR001811 // Chemokine interleukin-8-like domain // 7.5E-25"
"204612_at",-1.077673596,-1.018000711,-1.243659179,"DOWN","NM_006823","chr8:79428335-79515449 (+) // 97.39 // q21.12","protein kinase (cAMP-dependent, catalytic) inhibitor alpha","PKIA","ENSG00000171033 /// OTTHUMG00000164618","5569","606059","NP_006814 /// NP_862822","NM_006823 /// NM_181839","0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0010389 // regulation of G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0042308 // negative regulation of protein import into nucleus // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from electronic annotation /// 2000480 // negative regulation of cAMP-dependent protein kinase activity // inferred from direct assay","0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation","0004860 // protein kinase inhibitor activity // inferred from electronic annotation /// 0004862 // cAMP-dependent protein kinase inhibitor activity // inferred from direct assay /// 0004862 // cAMP-dependent protein kinase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0034236 // protein kinase A catalytic subunit binding // inferred from physical interaction","Calcium_regulation_in_cardiac_cells // GenMAPP /// Smooth_muscle_contraction // GenMAPP","IPR004171 // cAMP-dependent protein kinase inhibitor // 4.5E-38"
"204619_s_at",2.076647327,1.445310934,1.659325744,"UP","BF590263","chr5:82767478-82878121 (+) // 98.58 // q14.2","versican","VCAN","ENSG00000038427 /// OTTHUMG00000131321","1462","118661 /// 143200","NP_001119808 /// NP_001157569 /// NP_001157570 /// NP_004376","NM_001126336 /// NM_001164097 /// NM_001164098 /// NM_004385","0001649 // osteoblast differentiation // inferred from direct assay /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008037 // cell recognition // traceable author statement /// 0008347 // glial cell migration // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement","0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay","0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005539 // glycosaminoglycan binding // traceable author statement /// 0005540 // hyaluronic acid binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation","---","IPR000436 // Sushi/SCR/CCP // 8.6E-11 /// IPR000436 // Sushi/SCR/CCP // 5.9E-11 /// IPR000436 // Sushi/SCR/CCP // 3.8E-11 /// IPR000538 // Link // 5.9E-41 /// IPR000538 // Link // 3.9E-36 /// IPR000538 // Link // 4.0E-41 /// IPR000538 // Link // 2.6E-36 /// IPR000538 // Link // 2.5E-41 /// IPR000538 // Link // 1.7E-36 /// IPR000742 // Epidermal growth factor-like domain // 1.9E-9 /// IPR000742 // Epidermal growth factor-like domain // 3.8E-9 /// IPR000742 // Epidermal growth factor-like domain // 1.3E-9 /// IPR000742 // Epidermal growth factor-like domain // 2.7E-9 /// IPR000742 // Epidermal growth factor-like domain // 8.7E-10 /// IPR000742 // Epidermal growth factor-like domain // 1.8E-9 /// IPR001304 // C-type lectin // 2.6E-28 /// IPR001304 // C-type lectin // 1.7E-28 /// IPR001304 // C-type lectin // 1.1E-28 /// IPR013106 // Immunoglobulin V-set domain // 9.7E-17 /// IPR013106 // Immunoglobulin V-set domain // 6.5E-17 /// IPR013106 // Immunoglobulin V-set domain // 4.1E-17"
"204620_s_at",2.008481013,1.813561418,1.34727087,"UP","NM_004385","chr5:82767582-82876981 (+) // 99.65 // q14.2","versican","VCAN","ENSG00000038427 /// OTTHUMG00000131321","1462","118661 /// 143200","NP_001119808 /// NP_001157569 /// NP_001157570 /// NP_004376","NM_001126336 /// NM_001164097 /// NM_001164098 /// NM_004385","0001649 // osteoblast differentiation // inferred from direct assay /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008037 // cell recognition // traceable author statement /// 0008347 // glial cell migration // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement","0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay","0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005539 // glycosaminoglycan binding // traceable author statement /// 0005540 // hyaluronic acid binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation","---","IPR000436 // Sushi/SCR/CCP // 8.6E-11 /// IPR000436 // Sushi/SCR/CCP // 3.7E-11 /// IPR000436 // Sushi/SCR/CCP // 5.9E-11 /// IPR000436 // Sushi/SCR/CCP // 3.8E-11 /// IPR000538 // Link // 5.9E-41 /// IPR000538 // Link // 3.9E-36 /// IPR000538 // Link // 2.5E-41 /// IPR000538 // Link // 1.6E-36 /// IPR000538 // Link // 4.0E-41 /// IPR000538 // Link // 2.6E-36 /// IPR000538 // Link // 2.5E-41 /// IPR000538 // Link // 1.7E-36 /// IPR000742 // Epidermal growth factor-like domain // 1.9E-9 /// IPR000742 // Epidermal growth factor-like domain // 3.8E-9 /// IPR000742 // Epidermal growth factor-like domain // 8.4E-10 /// IPR000742 // Epidermal growth factor-like domain // 1.7E-9 /// IPR000742 // Epidermal growth factor-like domain // 1.3E-9 /// IPR000742 // Epidermal growth factor-like domain // 2.7E-9 /// IPR000742 // Epidermal growth factor-like domain // 8.7E-10 /// IPR000742 // Epidermal growth factor-like domain // 1.8E-9 /// IPR001304 // C-type lectin // 2.6E-28 /// IPR001304 // C-type lectin // 1.1E-28 /// IPR001304 // C-type lectin // 1.7E-28 /// IPR001304 // C-type lectin // 1.1E-28 /// IPR013106 // Immunoglobulin V-set domain // 9.7E-17 /// IPR013106 // Immunoglobulin V-set domain // 1.2E-12 /// IPR013106 // Immunoglobulin V-set domain // 6.5E-17 /// IPR013106 // Immunoglobulin V-set domain // 4.1E-17"
"204623_at",-4.461830254,-3.29051748,-4.055833026,"DOWN","NM_003226","chr21:43732183-43735463 (-) // 97.74 // q22.3","trefoil factor 3 (intestinal)","TFF3","ENSG00000160180 /// OTTHUMG00000086798","7033","600633","NP_003217","NM_003226","0006952 // defense response // traceable author statement /// 0007586 // digestion // traceable author statement /// 0043434 // response to peptide hormone // inferred from electronic annotation","0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0032579 // apical lamina of hyaline layer // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","---","---","IPR000519 // P-type trefoil // 1.3E-22 /// IPR000519 // P-type trefoil // 2.7E-22"
"204686_at",-1.329086124,-1.429416654,-1.380823991,"DOWN","NM_005544","chr2:227599937-227664475 (-) // 97.31 // q36.3","insulin receptor substrate 1","IRS1","ENSG00000169047 /// OTTHUMG00000133179","3667","125853 /// 147545","NP_005535 /// XP_005246591 /// XP_006712575","NM_005544 /// XM_005246534 /// XM_006712512","0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008284 // positive regulation of cell proliferation // non-traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // inferred from mutant phenotype /// 0008286 // insulin receptor signaling pathway // inferred from physical interaction /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010907 // positive regulation of glucose metabolic process // inferred from mutant phenotype /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0032000 // positive regulation of fatty acid beta-oxidation // inferred from mutant phenotype /// 0032868 // response to insulin // inferred from direct assay /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0034504 // protein localization to nucleus // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042593 // glucose homeostasis // traceable author statement /// 0043434 // response to peptide hormone // inferred from sequence or structural similarity /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from mutant phenotype /// 0045725 // positive regulation of glycogen biosynthetic process // non-traceable author statement /// 0046326 // positive regulation of glucose import // inferred from mutant phenotype /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0046628 // positive regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0046676 // negative regulation of insulin secretion // inferred from direct assay /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from physical interaction /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 2001275 // positive regulation of glucose import in response to insulin stimulus // inferred from direct assay","0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005899 // insulin receptor complex // inferred from sequence or structural similarity /// 0005901 // caveola // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from sequence or structural similarity","0004871 // signal transducer activity // inferred from electronic annotation /// 0005068 // transmembrane receptor protein tyrosine kinase adaptor activity // inferred from sequence or structural similarity /// 0005080 // protein kinase C binding // inferred from sequence or structural similarity /// 0005158 // insulin receptor binding // inferred from physical interaction /// 0005159 // insulin-like growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0042169 // SH2 domain binding // inferred from sequence or structural similarity /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from sequence or structural similarity","---","IPR001849 // Pleckstrin homology domain // 3.3E-17 /// IPR002404 // Insulin receptor substrate-1, PTB // 3.6E-33"
"204702_s_at",2.520349592,1.312134805,1.594423405,"UP","NM_004289","chr17:45501520-45504005 (+) // 96.41 // q21.32 /// chr18:57636940-57639114 (+) // 96.87 // q21.32 /// chr7:26192508-26225882 (+) // 100.0 // p15.2","nuclear factor, erythroid 2-like 3","NFE2L3","ENSG00000050344 /// OTTHUMG00000023882","9603","604135","NP_004280","NM_004289","0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement","0005634 // nucleus // inferred from electronic annotation","0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation","---","IPR004826 // Basic leucine zipper domain, Maf-type // 3.7E-10 /// IPR004827 // Basic-leucine zipper domain // 7.8E-12 /// IPR004827 // Basic-leucine zipper domain // 5.5E-9"
"204719_at",-1.577470535,-1.286866508,-1.856341984,"DOWN","NM_007168","chr17:66863432-66951492 (-) // 99.45 // q24.2","ATP-binding cassette, sub-family A (ABC1), member 8","ABCA8","ENSG00000141338 /// OTTHUMG00000180192","10351","612505","NP_001275914 /// NP_001275915 /// NP_009099 /// XP_005256995 /// XP_005256997","NM_001288985 /// NM_001288986 /// NM_007168 /// XM_005256938 /// XM_005256940 /// XR_243626","0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement","0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from direct assay","---","IPR003439 // ABC transporter-like // 1.1E-10 /// IPR003439 // ABC transporter-like // 3.3E-20 /// IPR003439 // ABC transporter-like // 9.5E-25 /// IPR003439 // ABC transporter-like // 3.4E-20"
"204745_x_at",-1.406584419,-1.427226248,-1.714539608,"DOWN","NM_005950","chr16:56700652-56701977 (-) // 99.24 // q13","metallothionein 1G","MT1G","ENSG00000125144 /// OTTHUMG00000133275","4495","156353","NP_005941","NM_005950","0030224 // monocyte differentiation // non-traceable author statement /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from expression pattern /// 0042117 // monocyte activation // non-traceable author statement /// 0045926 // negative regulation of growth // inferred from direct assay /// 0071276 // cellular response to cadmium ion // inferred from expression pattern /// 0071280 // cellular response to copper ion // inferred from expression pattern /// 0071294 // cellular response to zinc ion // inferred from direct assay /// 0071294 // cellular response to zinc ion // inferred from expression pattern","0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay","0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR003019 // Metallothionein superfamily, eukaryotic // 5.3E-17 /// IPR003019 // Metallothionein superfamily, eukaryotic // 5.2E-16"
"204753_s_at",-1.751871312,-1.689012908,-1.111452424,"DOWN","AI810712","chr17:53342399-53402425 (+) // 96.63 // q22","hepatic leukemia factor","HLF","ENSG00000108924 /// OTTHUMG00000177840","3131","142385","NP_002117 /// XP_005257326","NM_002126 /// XM_005257269","0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation","0005634 // nucleus // inferred from electronic annotation","0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation","---","IPR004827 // Basic-leucine zipper domain // 3.5E-21 /// IPR004827 // Basic-leucine zipper domain // 1.9E-21"
"204754_at",-1.32894856,-1.182857013,-1.967967434,"DOWN","W60800","chr17:53342399-53402425 (+) // 96.63 // q22","hepatic leukemia factor","HLF","ENSG00000108924 /// OTTHUMG00000177840","3131","142385","NP_002117 /// XP_005257326","NM_002126 /// XM_005257269","0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation","0005634 // nucleus // inferred from electronic annotation","0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation","---","IPR004827 // Basic-leucine zipper domain // 3.5E-21"
"204755_x_at",-1.589285968,-1.641918182,-1.108934786,"DOWN","M95585","chr17:53342526-53400888 (+) // 97.1 // q22","hepatic leukemia factor","HLF","ENSG00000108924 /// OTTHUMG00000177840","3131","142385","NP_002117 /// XP_005257326","NM_002126 /// XM_005257269","0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0048511 // rhythmic process // inferred from electronic annotation","0005634 // nucleus // inferred from electronic annotation","0003677 // DNA binding // traceable author statement /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation","---","IPR004827 // Basic-leucine zipper domain // 3.5E-21 /// IPR004827 // Basic-leucine zipper domain // 1.9E-21"
"204796_at",-1.344065734,-1.30059671,-1.158409228,"DOWN","AI825937","chr14:100259758-100408393 (+) // 97.13 // q32.2","echinoderm microtubule associated protein like 1","EML1","ENSG00000066629 /// OTTHUMG00000171529","2009","602033","NP_001008707 /// NP_004425 /// XP_005267454 /// XP_005267455 /// XP_005267456 /// XP_005267457 /// XP_006720137","NM_001008707 /// NM_004434 /// XM_005267397 /// XM_005267398 /// XM_005267399 /// XM_005267400 /// XM_006720074","0000226 // microtubule cytoskeleton organization // inferred from sequence or structural similarity /// 0007052 // mitotic spindle organization // inferred from sequence or structural similarity /// 0007405 // neuroblast proliferation // inferred from sequence or structural similarity /// 0007420 // brain development // inferred from mutant phenotype /// 0007420 // brain development // inferred from sequence or structural similarity","0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0097431 // mitotic spindle pole // inferred from sequence or structural similarity /// 1990023 // mitotic spindle midzone // inferred from sequence or structural similarity","0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0015631 // tubulin binding // inferred from direct assay","---","IPR001680 // WD40 repeat // 3.2E-6 /// IPR001680 // WD40 repeat // 3.4E-4 /// IPR001680 // WD40 repeat // 1.6E-7 /// IPR001680 // WD40 repeat // 1.3E-6 /// IPR001680 // WD40 repeat // 7.8E-8 /// IPR001680 // WD40 repeat // 2.3E-7 /// IPR005108 // HELP // 1.6E-42"
"204869_at",2.671440011,1.787175165,2.298439247,"UP","AL031664","chr20:17207646-17465218 (+) // 96.9 // p12.1","proprotein convertase subtilisin/kexin type 2","PCSK2","ENSG00000125851 /// OTTHUMG00000031941","5126","162151","NP_001188457 /// NP_001188458 /// NP_002585","NM_001201528 /// NM_001201529 /// NM_002594","0006508 // proteolysis // inferred from direct assay /// 0007399 // nervous system development // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0016485 // protein processing // inferred from electronic annotation /// 0016486 // peptide hormone processing // inferred from electronic annotation /// 0016540 // protein autoprocessing // inferred from electronic annotation /// 0030070 // insulin processing // inferred from direct assay /// 0034230 // enkephalin processing // inferred from sequence or structural similarity /// 0034231 // islet amyloid polypeptide processing // inferred from sequence or structural similarity /// 0044267 // cellular protein metabolic process // traceable author statement","0005615 // extracellular space // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030133 // transport vesicle // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0034774 // secretory granule lumen // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation","0004175 // endopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation","---","IPR000209 // Peptidase S8/S53 domain // 9.2E-70 /// IPR000209 // Peptidase S8/S53 domain // 9.9E-70 /// IPR002884 // Proprotein convertase, P // 5.4E-34 /// IPR002884 // Proprotein convertase, P // 5.7E-34"
"204870_s_at",2.760763516,2.214684629,1.862056024,"UP","NM_002594","chr20:17207864-17462925 (+) // 99.46 // p12.1","proprotein convertase subtilisin/kexin type 2","PCSK2","ENSG00000125851 /// OTTHUMG00000031941","5126","162151","NP_001188457 /// NP_001188458 /// NP_002585","NM_001201528 /// NM_001201529 /// NM_002594","0006508 // proteolysis // inferred from direct assay /// 0007399 // nervous system development // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0016485 // protein processing // inferred from electronic annotation /// 0016486 // peptide hormone processing // inferred from electronic annotation /// 0016540 // protein autoprocessing // inferred from electronic annotation /// 0030070 // insulin processing // inferred from direct assay /// 0034230 // enkephalin processing // inferred from sequence or structural similarity /// 0034231 // islet amyloid polypeptide processing // inferred from sequence or structural similarity /// 0044267 // cellular protein metabolic process // traceable author statement","0005615 // extracellular space // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0030133 // transport vesicle // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0034774 // secretory granule lumen // traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043204 // perikaryon // inferred from electronic annotation","0004175 // endopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0032403 // protein complex binding // inferred from electronic annotation","---","IPR000209 // Peptidase S8/S53 domain // 9.2E-70 /// IPR000209 // Peptidase S8/S53 domain // 9.9E-70 /// IPR000209 // Peptidase S8/S53 domain // 8.6E-70 /// IPR002884 // Proprotein convertase, P // 5.4E-34 /// IPR002884 // Proprotein convertase, P // 5.7E-34 /// IPR002884 // Proprotein convertase, P // 5.2E-34"
"204872_at",-1.326791248,-1.230314955,-1.36064192,"DOWN","NM_007005","chr9:82340466-82341654 (+) // 99.75 // q21.31","transducin-like enhancer of split 4","TLE4","ENSG00000106829","7091","605132","NP_001269677 /// NP_001269678 /// NP_001269682 /// NP_001269689 /// NP_008936 /// XP_005252224 /// XP_005252226 /// XP_005252230 /// XP_005252231 /// XP_005252232 /// XP_005252234 /// XP_006717327 /// XP_006717328 /// XP_006717329 /// XP_006717330 /// XP_006717331 /// XP_006717332 /// XP_006717333","NM_001282748 /// NM_001282749 /// NM_001282753 /// NM_001282760 /// NM_007005 /// NR_104239 /// XM_005252167 /// XM_005252169 /// XM_005252173 /// XM_005252174 /// XM_005252175 /// XM_005252177 /// XM_006717264 /// XM_006717265 /// XM_006717266 /// XM_006717267 /// XM_006717268 /// XM_006717269 /// XM_006717270","0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation","0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement","0003682 // chromatin binding // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from electronic annotation","---","IPR001680 // WD40 repeat // 5.2E-6 /// IPR001680 // WD40 repeat // 9.6E-6 /// IPR001680 // WD40 repeat // 7.8E-9 /// IPR001680 // WD40 repeat // 8.0E-12 /// IPR001680 // WD40 repeat // 1.4E-7 /// IPR001680 // WD40 repeat // 1.7E-6 /// IPR005617 // Groucho/TLE, N-terminal Q-rich domain // 4.7E-81"
"204918_s_at",-1.418609305,-1.18839249,-1.137195375,"DOWN","NM_004529","chr9:20344967-20622450 (-) // 93.78 // p21.3","myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3","MLLT3","ENSG00000171843 /// OTTHUMG00000019650","4300","159558","NP_001273620 /// NP_004520","NM_001286691 /// NM_004529","0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007379 // segment specification // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from genetic interaction /// 2000096 // positive regulation of Wnt signaling pathway, planar cell polarity pathway // inferred from genetic interaction","0005634 // nucleus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005515 // protein binding // inferred from physical interaction","---","IPR005033 // YEATS // 1.2E-31"
"204932_at",-1.981440382,-2.406379279,-2.390826332,"DOWN","BF433902","chr8:119935802-119964189 (-) // 99.03 // q24.12","tumor necrosis factor receptor superfamily, member 11b","TNFRSF11B","ENSG00000164761 /// OTTHUMG00000164969","4982","239000 /// 602643","NP_002537","NM_002546","0001501 // skeletal system development // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0032026 // response to magnesium ion // inferred from electronic annotation /// 0042489 // negative regulation of odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045779 // negative regulation of bone resorption // inferred from electronic annotation /// 0046685 // response to arsenic-containing substance // inferred from electronic annotation","0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay","0004872 // receptor activity // traceable author statement /// 0005125 // cytokine activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation","---","IPR000488 // Death domain // 1.6E-15 /// IPR001368 // TNFR/NGFR cysteine-rich region // 1.3E-9 /// IPR001368 // TNFR/NGFR cysteine-rich region // 7.0E-11"
"205016_at",2.041144373,1.959022994,1.746004391,"UP","NM_003236","chr2:70674418-70780930 (-) // 99.03 // p13.3","transforming growth factor, alpha","TGFA","ENSG00000163235 /// OTTHUMG00000129669","7039","190170","NP_001093161 /// NP_003227 /// XP_005264579","NM_001099691 /// NM_003236 /// XM_005264522","0000165 // MAPK cascade // inferred from direct assay /// 0000187 // activation of MAPK activity // inferred from direct assay /// 0001525 // angiogenesis // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0045741 // positive regulation of epidermal growth factor-activated receptor activity // inferred from direct assay /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0048523 // negative regulation of cellular process // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from direct assay /// 0051781 // positive regulation of cell division // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation","0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay","0001948 // glycoprotein binding // inferred from electronic annotation /// 0004708 // MAP kinase kinase activity // inferred from direct assay /// 0005154 // epidermal growth factor receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from direct assay","---","---"
"205051_s_at",-3.10022936,-2.685955634,-1.884495994,"DOWN","NM_000222","chr4:55524160-55606855 (+) // 97.23 // q12","v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog","KIT","ENSG00000157404 /// OTTHUMG00000128713","3815","154800 /// 164920 /// 172800 /// 273300 /// 606764","NP_000213 /// NP_001087241 /// XP_005265797 /// XP_005265798 /// XP_005265799 /// XP_006714101","NM_000222 /// NM_001093772 /// XM_005265740 /// XM_005265741 /// XM_005265742 /// XM_006714038","0000187 // activation of MAPK activity // inferred from direct assay /// 0001541 // ovarian follicle development // inferred from sequence or structural similarity /// 0002318 // myeloid progenitor cell differentiation // inferred from electronic annotation /// 0002320 // lymphoid progenitor cell differentiation // inferred from electronic annotation /// 0002327 // immature B cell differentiation // inferred from sequence or structural similarity /// 0002371 // dendritic cell cytokine production // inferred from sequence or structural similarity /// 0002551 // mast cell chemotaxis // inferred from direct assay /// 0002573 // myeloid leukocyte differentiation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006687 // glycosphingolipid metabolic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0007283 // spermatogenesis // traceable author statement /// 0007286 // spermatid development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008354 // germ cell migration // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from sequence or structural similarity /// 0008542 // visual learning // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008584 // male gonad development // inferred from expression pattern /// 0009314 // response to radiation // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010863 // positive regulation of phospholipase C activity // traceable author statement /// 0014068 // positive regulation of phosphatidylinositol 3-kinase signaling // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0019827 // stem cell maintenance // traceable author statement /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0023014 // signal transduction by phosphorylation // traceable author statement /// 0030032 // lamellipodium assembly // inferred from sequence or structural similarity /// 0030097 // hemopoiesis // traceable author statement /// 0030217 // T cell differentiation // inferred from sequence or structural similarity /// 0030218 // erythrocyte differentiation // inferred from sequence or structural similarity /// 0030318 // melanocyte differentiation // inferred from sequence or structural similarity /// 0030318 // melanocyte differentiation // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0031274 // positive regulation of pseudopodium assembly // inferred from electronic annotation /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0032762 // mast cell cytokine production // inferred from direct assay /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from sequence or structural similarity /// 0035234 // ectopic germ cell programmed cell death // inferred from electronic annotation /// 0035855 // megakaryocyte development // inferred from sequence or structural similarity /// 0038093 // Fc receptor signaling pathway // inferred from direct assay /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038109 // Kit signaling pathway // inferred from direct assay /// 0038162 // erythropoietin-mediated signaling pathway // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // traceable author statement /// 0042511 // positive regulation of tyrosine phosphorylation of Stat1 protein // inferred from mutant phenotype /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from mutant phenotype /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from mutant phenotype /// 0043069 // negative regulation of programmed cell death // inferred from electronic annotation /// 0043303 // mast cell degranulation // inferred from mutant phenotype /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0043473 // pigmentation // inferred from sequence or structural similarity /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045747 // positive regulation of Notch signaling pathway // inferred from electronic annotation /// 0046427 // positive regulation of JAK-STAT cascade // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048066 // developmental pigmentation // inferred from electronic annotation /// 0048070 // regulation of developmental pigmentation // inferred from electronic annotation /// 0048103 // somatic stem cell division // inferred from electronic annotation /// 0048170 // positive regulation of long-term neuronal synaptic plasticity // inferred from electronic annotation /// 0048565 // digestive tract development // inferred from sequence or structural similarity /// 0048863 // stem cell differentiation // inferred from sequence or structural similarity /// 0050673 // epithelial cell proliferation // inferred from electronic annotation /// 0050910 // detection of mechanical stimulus involved in sensory perception of sound // inferred from sequence or structural similarity /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from mutant phenotype /// 0060326 // cell chemotaxis // inferred from direct assay /// 0060374 // mast cell differentiation // inferred from sequence or structural similarity /// 0060374 // mast cell differentiation // traceable author statement /// 0070662 // mast cell proliferation // traceable author statement /// 0097067 // cellular response to thyroid hormone stimulus // inferred from electronic annotation /// 0097324 // melanocyte migration // inferred from sequence or structural similarity /// 0097326 // melanocyte adhesion // inferred from sequence or structural similarity","0001669 // acrosomal vesicle // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009898 // cytoplasmic side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from mutant phenotype","0000166 // nucleotide binding // inferred from electronic annotation /// 0002020 // protease binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0004716 // receptor signaling protein tyrosine kinase activity // inferred from electronic annotation /// 0005020 // stem cell factor receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019955 // cytokine binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000719 // Protein kinase domain // 5.2E-15 /// IPR000719 // Protein kinase domain // 2.5E-34 /// IPR001245 // Serine-threonine/tyrosine-protein kinase catalytic domain // 2.6E-107 /// IPR013098 // Immunoglobulin I-set // 5.6E-13 /// IPR013151 // Immunoglobulin // 1.8E-14"
"205076_s_at",1.626414326,1.052982996,1.747940213,"UP","NM_006697","chr1:149900543-149908727 (-) // 98.94 // q21.2","myotubularin related protein 11","MTMR11","ENSG00000014914 /// OTTHUMG00000012207","10903","---","NP_001139334 /// NP_870988 /// XP_006711198 /// XP_006711199 /// XP_006711200","NM_001145862 /// NM_006697 /// NM_181873 /// XM_006711135 /// XM_006711136 /// XM_006711137 /// XR_426759 /// XR_426760","0016311 // dephosphorylation // inferred from electronic annotation","---","0016791 // phosphatase activity // inferred from electronic annotation","---","IPR010569 // Myotubularin-like phosphatase domain // 9.3E-11 /// IPR022587 // Myotubularin-associated // 4.3E-31"
"205083_at",-2.6580029,-1.933043923,-1.503888227,"DOWN","NM_001159","chr2:201450537-201536214 (+) // 93.09 // q33.1","aldehyde oxidase 1","AOX1","---","316","602841","NP_001150","NM_001159","0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0042816 // vitamin B6 metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // traceable author statement","0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0003824 // catalytic activity // inferred from electronic annotation /// 0004031 // aldehyde oxidase activity // traceable author statement /// 0004854 // xanthine dehydrogenase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008762 // UDP-N-acetylmuramate dehydrogenase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016614 // oxidoreductase activity, acting on CH-OH group of donors // inferred from electronic annotation /// 0043546 // molybdopterin cofactor binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051537 // 2 iron, 2 sulfur cluster binding // inferred from electronic annotation","PWY66-201 // HumanCyc /// PWY66-221 // HumanCyc","---"
"205084_at",-1.013287297,-1.11080783,-1.022151789,"DOWN","NM_018844","chr7:107220714-107259099 (+) // 96.77 // q22.3","B-cell receptor-associated protein 29","BCAP29","ENSG00000075790 /// OTTHUMG00000154770","55973","---","NP_001008405 /// NP_061332 /// XP_006716114","NM_001008405 /// NM_001008406 /// NM_001008407 /// NM_018844 /// NR_027830 /// XM_006716051","0001649 // osteoblast differentiation // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation","0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation","---","---","IPR008417 // B-cell receptor-associated protein 29/31 // 9.9E-66 /// IPR008417 // B-cell receptor-associated protein 29/31 // 9.2E-31 /// IPR008417 // B-cell receptor-associated protein 29/31 // 3.4E-65"
"205088_at",1.73964926,1.065775785,1.789091092,"UP","NM_005491","chrX:149613719-149682439 (+) // 95.11 // q28","mastermind-like domain containing 1","MAMLD1","ENSG00000013619 /// OTTHUMG00000024157","10046","300120 /// 300758","NP_001170936 /// NP_001170937 /// NP_005482 /// XP_005274693 /// XP_006724865 /// XP_006724866","NM_001177465 /// NM_001177466 /// NM_005491 /// XM_005274636 /// XM_006724802 /// XM_006724803","0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0008584 // male gonad development // inferred from expression pattern","0005634 // nucleus // inferred from electronic annotation","---","---","---"
"205174_s_at",2.760174621,2.874976478,2.510590392,"UP","NM_012413","chr2:37571868-37600464 (+) // 97.01 // p22.2","glutaminyl-peptide cyclotransferase","QPCT","ENSG00000115828 /// OTTHUMG00000100963","25797","607065","NP_036545","NM_012413","0006464 // cellular protein modification process // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0017186 // peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase // inferred from direct assay","0005576 // extracellular region // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0008233 // peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from direct assay /// 0016603 // glutaminyl-peptide cyclotransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR007484 // Peptidase M28 // 4.2E-48"
"205221_at",-2.688873024,-2.528820078,-2.906553494,"DOWN","NM_000187","chr3:120347018-120401125 (-) // 99.83 // q13.33","homogentisate 1,2-dioxygenase","HGD","ENSG00000113924 /// OTTHUMG00000159441","3081","203500 /// 607474","NP_000178 /// XP_005247469 /// XP_005247470 /// XP_005247471","NM_000187 /// XM_005247412 /// XM_005247413 /// XM_005247414","0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0006559 // L-phenylalanine catabolic process // inferred from electronic annotation /// 0006559 // L-phenylalanine catabolic process // traceable author statement /// 0006570 // tyrosine metabolic process // inferred from electronic annotation /// 0006572 // tyrosine catabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation","0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0004411 // homogentisate 1,2-dioxygenase activity // not recorded /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation","TYRFUMCAT-PWY // HumanCyc","IPR005708 // Homogentisate 1,2-dioxygenase // 1.2E-212 /// IPR005708 // Homogentisate 1,2-dioxygenase // 4.3E-26 /// IPR005708 // Homogentisate 1,2-dioxygenase // 4.2E-19"
"205227_at",1.738671687,1.009155438,1.76301514,"UP","NM_002182","chr3:190231890-190369301 (+) // 90.45 // q28","interleukin 1 receptor accessory protein","IL1RAP","ENSG00000196083 /// OTTHUMG00000156211","3556","602626","NP_001161400 /// NP_001161401 /// NP_001161402 /// NP_001161403 /// NP_002173 /// NP_608273 /// XP_005247490 /// XP_005247491","NM_001167928 /// NM_001167929 /// NM_001167930 /// NM_001167931 /// NM_002182 /// NM_134470 /// XM_005247433 /// XM_005247434","0006461 // protein complex assembly // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0042094 // interleukin-2 biosynthetic process // inferred from electronic annotation","0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0004871 // signal transducer activity // traceable author statement /// 0004908 // interleukin-1 receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation","---","IPR000157 // Toll/interleukin-1 receptor homology (TIR) domain // 2.6E-38 /// IPR013151 // Immunoglobulin // 2.6E-8"
"205249_at",-1.343714846,-1.135018331,-1.107073952,"DOWN","NM_000399","chr10:64571756-64576127 (-) // 99.56 // q21.3","early growth response 2","EGR2","---","1959","129010 /// 145900 /// 605253 /// 607678","NP_000390 /// NP_001129649 /// NP_001129650 /// NP_001129651 /// XP_005269647","NM_000399 /// NM_001136177 /// NM_001136178 /// NM_001136179 /// XM_005269590","0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006611 // protein export from nucleus // inferred from sequence or structural similarity /// 0007420 // brain development // traceable author statement /// 0007422 // peripheral nervous system development // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0007622 // rhythmic behavior // inferred from electronic annotation /// 0008045 // motor neuron axon guidance // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0014037 // Schwann cell differentiation // inferred from electronic annotation /// 0016925 // protein sumoylation // inferred from electronic annotation /// 0021569 // rhombomere 3 development // inferred from electronic annotation /// 0021612 // facial nerve structural organization // inferred from electronic annotation /// 0021660 // rhombomere 3 formation // inferred from electronic annotation /// 0021666 // rhombomere 5 formation // inferred from electronic annotation /// 0030278 // regulation of ossification // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0035284 // brain segmentation // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // not recorded /// 0042552 // myelination // not recorded /// 0043066 // negative regulation of apoptotic process // not recorded /// 0045444 // fat cell differentiation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048168 // regulation of neuronal synaptic plasticity // not recorded /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071320 // cellular response to cAMP // not recorded /// 0071371 // cellular response to gonadotropin stimulus // not recorded","0005634 // nucleus // not recorded /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // not recorded /// 0005737 // cytoplasm // inferred from sequence or structural similarity","0001102 // RNA polymerase II activating transcription factor binding // inferred from sequence or structural similarity /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation /// 0071837 // HMG box domain binding // inferred from electronic annotation","---","---"
"205289_at",-1.458162218,-1.138611658,-2.08914221,"DOWN","AA583044","chr20:6748310-6760923 (+) // 97.71 // p12.3","bone morphogenetic protein 2","BMP2","ENSG00000125845 /// OTTHUMG00000031833","650","112261 /// 112600 /// 235200","NP_001191","NM_001200","0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000187 // activation of MAPK activity // inferred from direct assay /// 0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0002062 // chondrocyte differentiation // inferred from direct assay /// 0003130 // BMP signaling pathway involved in heart induction // inferred from direct assay /// 0003181 // atrioventricular valve morphogenesis // inferred from sequence or structural similarity /// 0003203 // endocardial cushion morphogenesis // inferred from sequence or structural similarity /// 0003308 // negative regulation of Wnt signaling pathway involved in heart development // inferred from direct assay /// 0006029 // proteoglycan metabolic process // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0007219 // Notch signaling pathway // inferred from sequence or structural similarity /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0009887 // organ morphogenesis // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from mutant phenotype /// 0010894 // negative regulation of steroid biosynthetic process // inferred from direct assay /// 0010922 // positive regulation of phosphatase activity // inferred from direct assay /// 0021537 // telencephalon development // inferred from direct assay /// 0021978 // telencephalon regionalization // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // traceable author statement /// 0030282 // bone mineralization // inferred from sequence or structural similarity /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0030501 // positive regulation of bone mineralization // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from expression pattern /// 0030509 // BMP signaling pathway // inferred from mutant phenotype /// 0030509 // BMP signaling pathway // traceable author statement /// 0031648 // protein destabilization // inferred from electronic annotation /// 0032348 // negative regulation of aldosterone biosynthetic process // inferred from direct assay /// 0033690 // positive regulation of osteoblast proliferation // inferred from sequence or structural similarity /// 0035051 // cardiocyte differentiation // inferred from direct assay /// 0035051 // cardiocyte differentiation // inferred from mutant phenotype /// 0035054 // embryonic heart tube anterior/posterior pattern specification // inferred from sequence or structural similarity /// 0035630 // bone mineralization involved in bone maturation // inferred from direct assay /// 0040007 // growth // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from sequence or structural similarity /// 0042482 // positive regulation of odontogenesis // inferred from sequence or structural similarity /// 0042487 // regulation of odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0043569 // negative regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045600 // positive regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045669 // positive regulation of osteoblast differentiation // inferred from direct assay /// 0045778 // positive regulation of ossification // inferred from direct assay /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048711 // positive regulation of astrocyte differentiation // inferred from sequence or structural similarity /// 0048762 // mesenchymal cell differentiation // inferred from direct assay /// 0048839 // inner ear development // inferred from sequence or structural similarity /// 0051042 // negative regulation of calcium-independent cell-cell adhesion // inferred from direct assay /// 0051216 // cartilage development // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from mutant phenotype /// 0055008 // cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from sequence or structural similarity /// 0060039 // pericardium development // inferred from sequence or structural similarity /// 0060128 // corticotropin hormone secreting cell differentiation // inferred from sequence or structural similarity /// 0060129 // thyroid-stimulating hormone-secreting cell differentiation // inferred from sequence or structural similarity /// 0060317 // cardiac epithelial to mesenchymal transition // inferred from direct assay /// 0060389 // pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0060485 // mesenchyme development // inferred from mutant phenotype /// 0060804 // positive regulation of Wnt signaling pathway by BMP signaling pathway // inferred from sequence or structural similarity /// 0061036 // positive regulation of cartilage development // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071773 // cellular response to BMP stimulus // inferred from direct assay /// 0072138 // mesenchymal cell proliferation involved in ureteric bud development // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from expression pattern /// 1900745 // positive regulation of p38MAPK cascade // inferred from direct assay /// 1901522 // positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus // inferred from direct assay /// 2000065 // negative regulation of cortisol biosynthetic process // inferred from direct assay /// 2000726 // negative regulation of cardiac muscle cell differentiation // inferred from direct assay","0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay","0004745 // retinol dehydrogenase activity // inferred from sequence or structural similarity /// 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0019211 // phosphatase activator activity // inferred from direct assay /// 0046332 // SMAD binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0070700 // BMP receptor binding // inferred from direct assay","---","IPR001111 // Transforming growth factor-beta, N-terminal // 1.7E-75 /// IPR001839 // Transforming growth factor-beta, C-terminal // 1.3E-45"
"205290_s_at",-1.375195853,-1.026320635,-1.807966594,"DOWN","NM_001200","chr20:6749206-6759769 (+) // 98.77 // p12.3","bone morphogenetic protein 2","BMP2","ENSG00000125845 /// OTTHUMG00000031833","650","112261 /// 112600 /// 235200","NP_001191","NM_001200","0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000187 // activation of MAPK activity // inferred from direct assay /// 0001501 // skeletal system development // traceable author statement /// 0001503 // ossification // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from direct assay /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0001938 // positive regulation of endothelial cell proliferation // inferred from direct assay /// 0002062 // chondrocyte differentiation // inferred from direct assay /// 0003130 // BMP signaling pathway involved in heart induction // inferred from direct assay /// 0003181 // atrioventricular valve morphogenesis // inferred from sequence or structural similarity /// 0003203 // endocardial cushion morphogenesis // inferred from sequence or structural similarity /// 0003308 // negative regulation of Wnt signaling pathway involved in heart development // inferred from direct assay /// 0006029 // proteoglycan metabolic process // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006954 // inflammatory response // inferred from sequence or structural similarity /// 0007219 // Notch signaling pathway // inferred from sequence or structural similarity /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0009887 // organ morphogenesis // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010718 // positive regulation of epithelial to mesenchymal transition // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from mutant phenotype /// 0010894 // negative regulation of steroid biosynthetic process // inferred from direct assay /// 0010922 // positive regulation of phosphatase activity // inferred from direct assay /// 0021537 // telencephalon development // inferred from direct assay /// 0021978 // telencephalon regionalization // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // traceable author statement /// 0030282 // bone mineralization // inferred from sequence or structural similarity /// 0030335 // positive regulation of cell migration // inferred from sequence or structural similarity /// 0030501 // positive regulation of bone mineralization // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0030509 // BMP signaling pathway // inferred from expression pattern /// 0030509 // BMP signaling pathway // inferred from mutant phenotype /// 0030509 // BMP signaling pathway // traceable author statement /// 0031648 // protein destabilization // inferred from electronic annotation /// 0032348 // negative regulation of aldosterone biosynthetic process // inferred from direct assay /// 0033690 // positive regulation of osteoblast proliferation // inferred from sequence or structural similarity /// 0035051 // cardiocyte differentiation // inferred from direct assay /// 0035051 // cardiocyte differentiation // inferred from mutant phenotype /// 0035054 // embryonic heart tube anterior/posterior pattern specification // inferred from sequence or structural similarity /// 0035630 // bone mineralization involved in bone maturation // inferred from direct assay /// 0040007 // growth // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from sequence or structural similarity /// 0042482 // positive regulation of odontogenesis // inferred from sequence or structural similarity /// 0042487 // regulation of odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043410 // positive regulation of MAPK cascade // inferred from direct assay /// 0043569 // negative regulation of insulin-like growth factor receptor signaling pathway // inferred from direct assay /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045600 // positive regulation of fat cell differentiation // inferred from sequence or structural similarity /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045669 // positive regulation of osteoblast differentiation // inferred from direct assay /// 0045778 // positive regulation of ossification // inferred from direct assay /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048711 // positive regulation of astrocyte differentiation // inferred from sequence or structural similarity /// 0048762 // mesenchymal cell differentiation // inferred from direct assay /// 0048839 // inner ear development // inferred from sequence or structural similarity /// 0051042 // negative regulation of calcium-independent cell-cell adhesion // inferred from direct assay /// 0051216 // cartilage development // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from mutant phenotype /// 0055008 // cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from sequence or structural similarity /// 0060039 // pericardium development // inferred from sequence or structural similarity /// 0060128 // corticotropin hormone secreting cell differentiation // inferred from sequence or structural similarity /// 0060129 // thyroid-stimulating hormone-secreting cell differentiation // inferred from sequence or structural similarity /// 0060317 // cardiac epithelial to mesenchymal transition // inferred from direct assay /// 0060389 // pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0060485 // mesenchyme development // inferred from mutant phenotype /// 0060804 // positive regulation of Wnt signaling pathway by BMP signaling pathway // inferred from sequence or structural similarity /// 0061036 // positive regulation of cartilage development // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071773 // cellular response to BMP stimulus // inferred from direct assay /// 0072138 // mesenchymal cell proliferation involved in ureteric bud development // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from expression pattern /// 1900745 // positive regulation of p38MAPK cascade // inferred from direct assay /// 1901522 // positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus // inferred from direct assay /// 2000065 // negative regulation of cortisol biosynthetic process // inferred from direct assay /// 2000726 // negative regulation of cardiac muscle cell differentiation // inferred from direct assay","0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay","0004745 // retinol dehydrogenase activity // inferred from sequence or structural similarity /// 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation /// 0019211 // phosphatase activator activity // inferred from direct assay /// 0046332 // SMAD binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0070700 // BMP receptor binding // inferred from direct assay","---","IPR001111 // Transforming growth factor-beta, N-terminal // 1.7E-75 /// IPR001839 // Transforming growth factor-beta, C-terminal // 1.3E-45"
"205328_at",2.557423662,1.816762685,3.611739627,"UP","NM_006984","chr13:96204981-96230491 (+) // 99.57 // q32.1","claudin 10","CLDN10","ENSG00000134873 /// OTTHUMG00000017217","9071","---","NP_001153572 /// NP_008915 /// NP_878268","NM_001160100 /// NM_006984 /// NM_182848","0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0016338 // calcium-independent cell-cell adhesion // inferred from sequence or structural similarity","0005886 // plasma membrane // inferred from electronic annotation /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation","0005198 // structural molecule activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from sequence or structural similarity","---","IPR004031 // PMP-22/EMP/MP20/Claudin superfamily // 2.9E-45 /// IPR004031 // PMP-22/EMP/MP20/Claudin superfamily // 1.0E-53"
"205350_at",-3.669217409,-2.04461222,-3.759178991,"DOWN","NM_004378","chr15:78632702-78640567 (+) // 91.29 // q25.1","cellular retinoic acid binding protein 1","CRABP1","ENSG00000166426 /// OTTHUMG00000143862","1381","180230","NP_004369","NM_004378","0006810 // transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement","0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation","0001972 // retinoic acid binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005501 // retinoid binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0016918 // retinal binding // inferred from electronic annotation /// 0019841 // retinol binding // inferred from electronic annotation","---","IPR000566 // Lipocalin/cytosolic fatty-acid binding domain // 7.5E-28 /// IPR000566 // Lipocalin/cytosolic fatty-acid binding domain // 1.9E-14"
"205357_s_at",-1.13449672,-2.312970646,-1.6592967,"DOWN","NM_000685","chr3:148415633-148460788 (+) // 98.11 // q24","angiotensin II receptor, type 1","AGTR1","ENSG00000144891 /// OTTHUMG00000159503","185","106165 /// 145500 /// 267430","NP_000676 /// NP_004826 /// NP_033611 /// NP_114038 /// NP_114438","NM_000685 /// NM_004835 /// NM_009585 /// NM_031850 /// NM_032049","0001558 // regulation of cell growth // non-traceable author statement /// 0001822 // kidney development // inferred from mutant phenotype /// 0002018 // renin-angiotensin regulation of aldosterone production // non-traceable author statement /// 0002034 // regulation of blood vessel size by renin-angiotensin // inferred by curator /// 0003081 // regulation of systemic arterial blood pressure by renin-angiotensin // inferred by curator /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // non-traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from direct assay /// 0007266 // Rho protein signal transduction // inferred from direct assay /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred by curator /// 0010873 // positive regulation of cholesterol esterification // inferred from mutant phenotype /// 0019229 // regulation of vasoconstriction // inferred by curator /// 0019229 // regulation of vasoconstriction // inferred from direct assay /// 0019229 // regulation of vasoconstriction // non-traceable author statement /// 0019722 // calcium-mediated signaling // inferred from direct assay /// 0032270 // positive regulation of cellular protein metabolic process // inferred from mutant phenotype /// 0032430 // positive regulation of phospholipase A2 activity // inferred from mutant phenotype /// 0033864 // positive regulation of NAD(P)H oxidase activity // traceable author statement /// 0034374 // low-density lipoprotein particle remodeling // non-traceable author statement /// 0035813 // regulation of renal sodium excretion // non-traceable author statement /// 0038166 // angiotensin-activated signaling pathway // inferred from direct assay /// 0042127 // regulation of cell proliferation // non-traceable author statement /// 0042312 // regulation of vasodilation // inferred by curator /// 0050727 // regulation of inflammatory response // inferred by curator /// 0050729 // positive regulation of inflammatory response // traceable author statement /// 0051482 // positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from direct assay /// 0086097 // phospholipase C-activating angiotensin-activated signaling pathway // inferred from direct assay /// 0086097 // phospholipase C-activating angiotensin-activated signaling pathway // inferred from physical interaction /// 2000379 // positive regulation of reactive oxygen species metabolic process // traceable author statement","0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred by curator /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement","0001596 // angiotensin type I receptor activity // inferred from direct assay /// 0001596 // angiotensin type I receptor activity // inferred from physical interaction /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004945 // angiotensin type II receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0010698 // acetyltransferase activator activity // inferred from mutant phenotype /// 0031711 // bradykinin receptor binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction","ACE-Inhibitor_pathway_PharmGKB // GenMAPP /// GPCRDB_Class_A_Rhodopsin-like // GenMAPP /// Peptide_GPCRs // GenMAPP","IPR000276 // G protein-coupled receptor, rhodopsin-like // 2.0E-67 /// IPR019424 // 7TM GPCR, olfactory receptor/chemoreceptor Srsx // 2.2E-12"
"205372_at",1.165161393,1.42087258,1.936819209,"UP","NM_002655","chr8:57073482-57123838 (-) // 98.0 // q12.1","pleiomorphic adenoma gene 1","PLAG1","ENSG00000181690 /// OTTHUMG00000164310","5324","181030 /// 603026","NP_001108106 /// NP_001108107 /// NP_002646 /// XP_005251317","NM_001114634 /// NM_001114635 /// NM_002655 /// XM_005251260","0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0022612 // gland morphogenesis // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0035265 // organ growth // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060252 // positive regulation of glial cell proliferation // inferred from electronic annotation /// 0060736 // prostate gland growth // inferred from electronic annotation","0005634 // nucleus // not recorded","0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation","---","---"
"205382_s_at",-2.188014471,-1.518129964,-1.897868284,"DOWN","NM_001928","chr19:859710-863569 (+) // 78.99 // p13.3","complement factor D (adipsin)","CFD","ENSG00000197766 /// OTTHUMG00000181840","1675","134350 /// 613912","NP_001919","NM_001928","0002376 // immune system process // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006956 // complement activation // traceable author statement /// 0006957 // complement activation, alternative pathway // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0045087 // innate immune response // traceable author statement","0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation","---","IPR001254 // Peptidase S1 // 7.0E-71 /// IPR015420 // Peptidase S1A, nudel // 8.0E-11"
"205402_x_at",2.570965811,1.395454036,2.514332148,"UP","NM_002770","chr7:142458404-142482416 (+) // 88.53 // q34","protease, serine, 2 (trypsin 2)","PRSS2","ENSG00000250591 /// OTTHUMG00000158904","5645","167800 /// 601564","NP_002761 /// XP_005277053 /// XP_005277055 /// XP_006716115 /// XP_006716116 /// XP_006725121","NM_002770 /// XM_005276996 /// XM_005276998 /// XM_006716052 /// XM_006716053 /// XM_006725058","0006508 // proteolysis // inferred from direct assay /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0007586 // digestion // inferred from electronic annotation /// 0009235 // cobalamin metabolic process // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030307 // positive regulation of cell growth // traceable author statement /// 0030574 // collagen catabolic process // inferred from direct assay /// 0030574 // collagen catabolic process // inferred from mutant phenotype /// 0030574 // collagen catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0045785 // positive regulation of cell adhesion // traceable author statement","0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from mutant phenotype /// 0031012 // extracellular matrix // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay","0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","---"
"205413_at",-3.437782465,-3.113952382,-3.517972827,"DOWN","NM_001584","chr11:30431773-30602040 (-) // 97.84 // p14.1","metallophosphoesterase domain containing 2","MPPED2","ENSG00000066382 /// OTTHUMG00000166159","744","600911","NP_001138871 /// NP_001575 /// XP_005253167 /// XP_005253168 /// XP_005253169 /// XP_005253170 /// XP_005253171 /// XP_006718367 /// XP_006718368","NM_001145399 /// NM_001584 /// XM_005253110 /// XM_005253111 /// XM_005253112 /// XM_005253113 /// XM_005253114 /// XM_006718304 /// XM_006718305","0007399 // nervous system development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation","---","0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR004843 // Calcineurin-like phosphoesterase domain, apaH type // 6.1E-12"
"205479_s_at",3.5809084,2.17194397,1.376233764,"UP","NM_002658","chr10:75670934-75677252 (+) // 96.88 // q22.2","plasminogen activator, urokinase","PLAU","ENSG00000122861 /// OTTHUMG00000018494","5328","104300 /// 191840 /// 601709","NP_001138503 /// NP_002649 /// XP_006717956","NM_001145031 /// NM_002658 /// XM_006717893","0001666 // response to hypoxia // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006935 // chemotaxis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0010469 // regulation of receptor activity // inferred from direct assay /// 0014909 // smooth muscle cell migration // inferred from electronic annotation /// 0014910 // regulation of smooth muscle cell migration // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0033628 // regulation of cell adhesion mediated by integrin // inferred from direct assay /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042730 // fibrinolysis // traceable author statement /// 0061041 // regulation of wound healing // inferred by curator /// 2000097 // regulation of smooth muscle cell-matrix adhesion // inferred from direct assay","0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation","Blood_Clotting_Cascade // GenMAPP /// Wnt_signaling // GenMAPP","IPR000001 // Kringle // 8.8E-27 /// IPR000001 // Kringle // 8.2E-27 /// IPR001254 // Peptidase S1 // 7.3E-73 /// IPR001254 // Peptidase S1 // 6.5E-73"
"205485_at",2.363775533,2.149223548,1.483424254,"UP","NM_000540","chr19:38924339-39078172 (+) // 97.25 // q13.2","ryanodine receptor 1 (skeletal)","RYR1","ENSG00000196218 /// OTTHUMG00000182403","6261","117000 /// 145600 /// 180901 /// 255310 /// 255320","NP_000531 /// NP_001036188 /// XP_006723380 /// XP_006723381 /// XP_006723382","NM_000540 /// NM_001042723 /// XM_006723317 /// XM_006723318 /// XM_006723319","0001666 // response to hypoxia // inferred from direct assay /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0006457 // protein folding // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from sequence or structural similarity /// 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0006915 // apoptotic process // non-traceable author statement /// 0006928 // cellular component movement // non-traceable author statement /// 0006936 // muscle contraction // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from direct assay /// 0014808 // release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0016485 // protein processing // non-traceable author statement /// 0017157 // regulation of exocytosis // non-traceable author statement /// 0019722 // calcium-mediated signaling // non-traceable author statement /// 0019724 // B cell mediated immunity // non-traceable author statement /// 0030100 // regulation of endocytosis // non-traceable author statement /// 0030183 // B cell differentiation // non-traceable author statement /// 0031000 // response to caffeine // inferred from sequence or structural similarity /// 0034220 // ion transmembrane transport // traceable author statement /// 0042100 // B cell proliferation // non-traceable author statement /// 0043588 // skin development // inferred from sequence or structural similarity /// 0043931 // ossification involved in bone maturation // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0048741 // skeletal muscle fiber development // inferred from sequence or structural similarity /// 0051209 // release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0051480 // cytosolic calcium ion homeostasis // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0071313 // cellular response to caffeine // inferred from sequence or structural similarity","0005737 // cytoplasm // inferred from direct assay /// 0005790 // smooth endoplasmic reticulum // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from direct assay /// 0014701 // junctional sarcoplasmic reticulum membrane // traceable author statement /// 0014802 // terminal cisterna // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred by curator /// 0016529 // sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0030314 // junctional membrane complex // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0031674 // I band // inferred from direct assay /// 0033017 // sarcoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0033017 // sarcoplasmic reticulum membrane // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0002020 // protease binding // inferred from electronic annotation /// 0004872 // receptor activity // inferred from direct assay /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005219 // ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0005219 // ryanodine-sensitive calcium-release channel activity // traceable author statement /// 0005245 // voltage-gated calcium channel activity // inferred from sequence or structural similarity /// 0005262 // calcium channel activity // inferred from sequence or structural similarity /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from sequence or structural similarity /// 0015085 // calcium ion transmembrane transporter activity // inferred from direct assay /// 0015278 // calcium-release channel activity // traceable author statement /// 0019899 // enzyme binding // inferred from electronic annotation","Calcium_regulation_in_cardiac_cells // GenMAPP /// Smooth_muscle_contraction // GenMAPP","IPR000699 // RIH (RyR and IP3R Homology) domain // 2.1E-73 /// IPR000699 // RIH (RyR and IP3R Homology) domain // 1.6E-66 /// IPR003032 // Ryanodine receptor Ryr // 4.1E-33 /// IPR003032 // Ryanodine receptor Ryr // 2.4E-30 /// IPR003032 // Ryanodine receptor Ryr // 3.0E-34 /// IPR003032 // Ryanodine receptor Ryr // 6.5E-33 /// IPR003877 // SPRY domain // 6.3E-28 /// IPR003877 // SPRY domain // 2.2E-30 /// IPR003877 // SPRY domain // 1.4E-28 /// IPR005821 // Ion transport domain // 6.7E-12 /// IPR005821 // Ion transport domain // 6.7E-12 /// IPR009460 // Ryanodine Receptor TM 4-6 // 2.4E-88 /// IPR009460 // Ryanodine Receptor TM 4-6 // 2.4E-88 /// IPR013662 // RyR/IP3R Homology associated domain // 5.5E-40 /// IPR013662 // RyR/IP3R Homology associated domain // 5.5E-40 /// IPR014821 // Inositol 1,4,5-trisphosphate/ryanodine receptor // 2.5E-72 /// IPR016093 // MIR motif // 7.5E-50"
"205490_x_at",1.249060005,1.106995148,1.161761076,"UP","BF060667","chr1:35249230-35252849 (+) // 80.62 // p34.3","gap junction protein, beta 3, 31kDa","GJB3","ENSG00000188910 /// OTTHUMG00000004051","2707","133200 /// 220290 /// 603324 /// 612644","NP_001005752 /// NP_076872","NM_001005752 /// NM_024009","0001701 // in utero embryonic development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0055085 // transmembrane transport // non-traceable author statement","0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005921 // gap junction // non-traceable author statement /// 0005922 // connexon complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation","0005243 // gap junction channel activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation","Calcium_regulation_in_cardiac_cells // GenMAPP","IPR013092 // Connexin, N-terminal // 4.1E-53 /// IPR019570 // Gap junction protein, cysteine-rich domain // 7.0E-30"
"205498_at",-2.014642916,-1.82043197,-1.662295139,"DOWN","NM_000163","chr5:42424025-42721979 (+) // 92.52 // p13.1","growth hormone receptor","GHR","ENSG00000112964 /// OTTHUMG00000094791","2690","143890 /// 262500 /// 600946 /// 604271","NP_000154 /// NP_001229328 /// NP_001229329 /// NP_001229330 /// NP_001229331 /// NP_001229332 /// NP_001229333 /// NP_001229334 /// NP_001229335 /// NP_001229389 /// NP_001229391 /// XP_005248345","NM_000163 /// NM_001242399 /// NM_001242400 /// NM_001242401 /// NM_001242402 /// NM_001242403 /// NM_001242404 /// NM_001242405 /// NM_001242406 /// NM_001242460 /// NM_001242461 /// NM_001242462 /// XM_005248288","0000187 // activation of MAPK activity // inferred from sequence or structural similarity /// 0000255 // allantoin metabolic process // inferred from sequence or structural similarity /// 0006101 // citrate metabolic process // inferred from sequence or structural similarity /// 0006103 // 2-oxoglutarate metabolic process // inferred from sequence or structural similarity /// 0006105 // succinate metabolic process // inferred from sequence or structural similarity /// 0006107 // oxaloacetate metabolic process // inferred from sequence or structural similarity /// 0006549 // isoleucine metabolic process // inferred from sequence or structural similarity /// 0006573 // valine metabolic process // inferred from sequence or structural similarity /// 0006600 // creatine metabolic process // inferred from sequence or structural similarity /// 0006631 // fatty acid metabolic process // inferred from sequence or structural similarity /// 0006897 // endocytosis // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // inferred from sequence or structural similarity /// 0009725 // response to hormone // inferred from electronic annotation /// 0009755 // hormone-mediated signaling pathway // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0019530 // taurine metabolic process // inferred from sequence or structural similarity /// 0031623 // receptor internalization // inferred from direct assay /// 0032094 // response to food // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from direct assay /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from mutant phenotype /// 0034097 // response to cytokine // inferred from electronic annotation /// 0040014 // regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040018 // positive regulation of multicellular organism growth // inferred from mutant phenotype /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from sequence or structural similarity /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from sequence or structural similarity /// 0042976 // activation of Janus kinase activity // inferred from electronic annotation /// 0042977 // activation of JAK2 kinase activity // inferred from sequence or structural similarity /// 0043278 // response to morphine // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0044236 // multicellular organismal metabolic process // inferred from mutant phenotype /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0046427 // positive regulation of JAK-STAT cascade // inferred from electronic annotation /// 0046449 // creatinine metabolic process // inferred from sequence or structural similarity /// 0046898 // response to cycloheximide // inferred from direct assay /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from mutant phenotype /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from sequence or structural similarity /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0060351 // cartilage development involved in endochondral bone morphogenesis // inferred from electronic annotation /// 0060396 // growth hormone receptor signaling pathway // inferred from mutant phenotype /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0070555 // response to interleukin-1 // inferred from electronic annotation /// 1901215 // negative regulation of neuron death // inferred from electronic annotation","0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from mutant phenotype /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0019898 // extrinsic component of membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070195 // growth hormone receptor complex // inferred from direct assay","0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004903 // growth hormone receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017046 // peptide hormone binding // inferred from physical interaction /// 0019838 // growth factor binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0019903 // protein phosphatase binding // inferred from electronic annotation /// 0042169 // SH2 domain binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0070064 // proline-rich region binding // inferred from sequence or structural similarity","---","IPR003961 // Fibronectin, type III // 1.9E-9 /// IPR003961 // Fibronectin, type III // 1.8E-9 /// IPR015152 // Growth hormone/erythropoietin receptor, ligand binding // 1.8E-14 /// IPR015152 // Growth hormone/erythropoietin receptor, ligand binding // 1.1E-14"
"205501_at",-1.576144476,-1.644018386,-1.206352621,"DOWN","AI143879","chr6:165740777-166075585 (-) // 96.32 // q27","phosphodiesterase 10A","PDE10A","ENSG00000112541 /// OTTHUMG00000015986","10846","610652","NP_001124162 /// XP_006715384","NM_001130690 /// NM_006661 /// NR_045597 /// XM_006715321","0006198 // cAMP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010738 // regulation of protein kinase A signaling // inferred from electronic annotation /// 0043949 // regulation of cAMP-mediated signaling // inferred from electronic annotation /// 0046069 // cGMP catabolic process // inferred from electronic annotation","0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement","0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // traceable author statement /// 0004118 // cGMP-stimulated cyclic-nucleotide phosphodiesterase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from direct assay /// 0030552 // cAMP binding // non-traceable author statement /// 0030553 // cGMP binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047555 // 3',5'-cyclic-GMP phosphodiesterase activity // inferred from electronic annotation","---","IPR002073 // 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain // 7.0E-70 /// IPR003018 // GAF domain // 8.2E-11 /// IPR003018 // GAF domain // 7.0E-30"
"205569_at",1.591090293,1.374700682,1.582410283,"UP","NM_014398","chr3:182840003-182880506 (-) // 83.42 // q27.1","lysosomal-associated membrane protein 3","LAMP3","ENSG00000078081 /// OTTHUMG00000158387","27074","605883","NP_055213 /// XP_005247417 /// XP_006713649","NM_014398 /// XM_005247360 /// XM_006713586","0002376 // immune system process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement","0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0097233 // alveolar lamellar body membrane // inferred from electronic annotation","---","---","IPR002000 // Lysosome-associated membrane glycoprotein // 5.6E-89"
"205579_at",1.780785991,1.075302978,1.489451457,"UP","NM_000861","chr3:11300686-11304415 (+) // 74.01 // p25.3","histamine receptor H1","HRH1","ENSG00000196639 /// OTTHUMG00000129719","3269","600167","NP_000852 /// NP_001091681 /// NP_001091682 /// NP_001091683","NM_000861 /// NM_001098211 /// NM_001098212 /// NM_001098213","0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007200 // phospholipase C-activating G-protein coupled receptor signaling pathway // traceable author statement /// 0007613 // memory // inferred from electronic annotation /// 0008542 // visual learning // inferred from electronic annotation /// 0032962 // positive regulation of inositol trisphosphate biosynthetic process // inferred from sequence or structural similarity /// 0043114 // regulation of vascular permeability // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0048016 // inositol phosphate-mediated signaling // inferred from sequence or structural similarity /// 0048167 // regulation of synaptic plasticity // inferred from electronic annotation /// 0048245 // eosinophil chemotaxis // inferred from electronic annotation /// 0071420 // cellular response to histamine // inferred from sequence or structural similarity","0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004969 // histamine receptor activity // inferred from sequence or structural similarity","GPCRDB_Class_A_Rhodopsin-like // GenMAPP /// Monoamine_GPCRs // GenMAPP","IPR000276 // G protein-coupled receptor, rhodopsin-like // 6.2E-77 /// IPR019424 // 7TM GPCR, olfactory receptor/chemoreceptor Srsx // 2.6E-10"
"205700_at",-2.134388156,-1.62729803,-1.076936208,"DOWN","NM_003725","chr12:57157117-57181568 (+) // 77.36 // q13.3","hydroxysteroid (17-beta) dehydrogenase 6","HSD17B6","ENSG00000025423 /// OTTHUMG00000170854","8630","606623","NP_003716 /// XP_005269264 /// XP_005269265 /// XP_005269266 /// XP_006719735","NM_003725 /// XM_005269207 /// XM_005269208 /// XM_005269209 /// XM_006719672 /// XR_245961","0006629 // lipid metabolic process // inferred from electronic annotation /// 0006702 // androgen biosynthetic process // non-traceable author statement /// 0006710 // androgen catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation","0005622 // intracellular // non-traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation","0003824 // catalytic activity // traceable author statement /// 0004303 // estradiol 17-beta-dehydrogenase activity // inferred from electronic annotation /// 0004745 // retinol dehydrogenase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // non-traceable author statement /// 0047035 // testosterone dehydrogenase (NAD+) activity // inferred from electronic annotation","---","IPR002198 // Short-chain dehydrogenase/reductase SDR // 7.0E-26"
"205710_at",-1.730297468,-1.259499495,-1.548931844,"DOWN","NM_004525","chr2:169984860-170219013 (-) // 99.87 // q31.1","low density lipoprotein receptor-related protein 2","LRP2","ENSG00000081479 /// OTTHUMG00000132179","4036","222448 /// 600073","NP_004516 /// XP_006712589 /// XP_006712590 /// XP_006712591","NM_004525 /// XM_006712526 /// XM_006712527 /// XM_006712528","0001523 // retinoid metabolic process // traceable author statement /// 0006486 // protein glycosylation // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement /// 0006766 // vitamin metabolic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // inferred from sequence or structural similarity /// 0006897 // endocytosis // traceable author statement /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0042359 // vitamin D metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement","0005764 // lysosome // traceable author statement /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005903 // brush border // inferred from electronic annotation /// 0005903 // brush border // inferred from sequence or structural similarity /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000033 // LDLR class B repeat // 9.0E-11 /// IPR000033 // LDLR class B repeat // 4.3E-9 /// IPR000033 // LDLR class B repeat // 4.8E-11 /// IPR000033 // LDLR class B repeat // 4.1E-15 /// IPR000033 // LDLR class B repeat // 2.8E-12 /// IPR000033 // LDLR class B repeat // 6.3E-14 /// IPR000033 // LDLR class B repeat // 4.7E-9 /// IPR000033 // LDLR class B repeat // 4.7E-10 /// IPR000033 // LDLR class B repeat // 2.7E-8 /// IPR000033 // LDLR class B repeat // 4.0E-18 /// IPR000033 // LDLR class B repeat // 1.1E-14 /// IPR000033 // LDLR class B repeat // 9.3E-11 /// IPR000033 // LDLR class B repeat // 2.6E-12 /// IPR000033 // LDLR class B repeat // 2.0E-13 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.6E-13 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 9.3E-14 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.1E-12 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 2.9E-14 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.2E-13 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 6.7E-10 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 8.1E-14 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.4E-15 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 5.4E-14 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.1E-15 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 2.5E-11 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 7.2E-12 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 4.7E-14 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 8.3E-9 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 3.2E-14 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 6.9E-15 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.2E-9 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.6E-10 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 6.0E-16 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 6.7E-14 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 3.3E-12 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 2.3E-13 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 5.3E-15 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 6.3E-14 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.2E-13 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 3.9E-9 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 2.6E-13 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 8.3E-17 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.6E-10 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 3.3E-15 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 7.7E-14 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.6E-13 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 5.8E-15 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 5.7E-12 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.4E-11"
"205713_s_at",2.42924851,3.370911824,1.291868538,"UP","NM_000095","chr19:18893583-18902100 (-) // 99.3 // p13.11","cartilage oligomeric matrix protein","COMP","ENSG00000105664 /// OTTHUMG00000169318","1311","132400 /// 177170 /// 600310","NP_000086","NM_000095","0001501 // skeletal system development // traceable author statement /// 0003417 // growth plate cartilage development // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0060173 // limb development // inferred from direct assay","0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0002020 // protease binding // inferred from physical interaction /// 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0043395 // heparan sulfate proteoglycan binding // inferred from direct assay","---","IPR001881 // EGF-like calcium-binding domain // 3.6E-10 /// IPR001881 // EGF-like calcium-binding domain // 1.7E-14 /// IPR001881 // EGF-like calcium-binding domain // 3.8E-10 /// IPR001881 // EGF-like calcium-binding domain // 1.8E-14 /// IPR001881 // EGF-like calcium-binding domain // 1.6E-14 /// IPR003367 // Thrombospondin, type 3-like repeat // 0.0056 /// IPR003367 // Thrombospondin, type 3-like repeat // 6.0E-5 /// IPR003367 // Thrombospondin, type 3-like repeat // 2.5E-7 /// IPR003367 // Thrombospondin, type 3-like repeat // 0.01 /// IPR003367 // Thrombospondin, type 3-like repeat // 8.5E-5 /// IPR003367 // Thrombospondin, type 3-like repeat // 4.5E-4 /// IPR003367 // Thrombospondin, type 3-like repeat // 1.7E-6 /// IPR003367 // Thrombospondin, type 3-like repeat // 0.019 /// IPR003367 // Thrombospondin, type 3-like repeat // 2.5E-6 /// IPR003367 // Thrombospondin, type 3-like repeat // 0.0031 /// IPR003367 // Thrombospondin, type 3-like repeat // 3.6E-4 /// IPR003367 // Thrombospondin, type 3-like repeat // 1.5E-5 /// IPR003367 // Thrombospondin, type 3-like repeat // 0.0049 /// IPR003367 // Thrombospondin, type 3-like repeat // 0.0059 /// IPR003367 // Thrombospondin, type 3-like repeat // 6.3E-5 /// IPR003367 // Thrombospondin, type 3-like repeat // 2.6E-7 /// IPR003367 // Thrombospondin, type 3-like repeat // 0.011 /// IPR003367 // Thrombospondin, type 3-like repeat // 8.9E-5 /// IPR003367 // Thrombospondin, type 3-like repeat // 4.7E-4 /// IPR003367 // Thrombospondin, type 3-like repeat // 1.8E-6 /// IPR003367 // Thrombospondin, type 3-like repeat // 0.02 /// IPR003367 // Thrombospondin, type 3-like repeat // 2.6E-6 /// IPR003367 // Thrombospondin, type 3-like repeat // 0.0032 /// IPR003367 // Thrombospondin, type 3-like repeat // 3.8E-4 /// IPR003367 // Thrombospondin, type 3-like repeat // 1.6E-5 /// IPR003367 // Thrombospondin, type 3-like repeat // 0.0052 /// IPR003367 // Thrombospondin, type 3-like repeat // 0.0054 /// IPR003367 // Thrombospondin, type 3-like repeat // 5.9E-5 /// IPR003367 // Thrombospondin, type 3-like repeat // 2.4E-7 /// IPR003367 // Thrombospondin, type 3-like repeat // 0.0098 /// IPR003367 // Thrombospondin, type 3-like repeat // 8.2E-5 /// IPR003367 // Thrombospondin, type 3-like repeat // 4.4E-4 /// IPR003367 // Thrombospondin, type 3-like repeat // 1.7E-6 /// IPR003367 // Thrombospondin, type 3-like repeat // 0.019 /// IPR003367 // Thrombospondin, type 3-like repeat // 2.4E-6 /// IPR003367 // Thrombospondin, type 3-like repeat // 0.0030 /// IPR003367 // Thrombospondin, type 3-like repeat // 3.5E-4 /// IPR003367 // Thrombospondin, type 3-like repeat // 1.5E-5 /// IPR003367 // Thrombospondin, type 3-like repeat // 0.0048 /// IPR008859 // Thrombospondin, C-terminal // 2.5E-110 /// IPR008859 // Thrombospondin, C-terminal // 2.7E-110 /// IPR008859 // Thrombospondin, C-terminal // 2.4E-110 /// IPR024665 // Thrombospondin/cartilage oligomeric matrix protein, coiled-coil domain // 7.1E-18 /// IPR024665 // Thrombospondin/cartilage oligomeric matrix protein, coiled-coil domain // 5.7E-20 /// IPR024665 // Thrombospondin/cartilage oligomeric matrix protein, coiled-coil domain // 5.2E-20"
"205728_at",3.775206661,3.766493486,2.762737028,"UP","AL022718","chrX:123509757-124097666 (-) // 98.88 // q25","teneurin transmembrane protein 1","TENM1","ENSG00000009694 /// OTTHUMG00000022721","10178","300588","NP_001156750 /// NP_001156751 /// NP_055068 /// XP_006724788","NM_001163278 /// NM_001163279 /// NM_014253 /// XM_006724725","0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006359 // regulation of transcription from RNA polymerase III promoter // inferred from sequence or structural similarity /// 0006950 // response to stress // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0030838 // positive regulation of actin filament polymerization // inferred from sequence or structural similarity /// 0033138 // positive regulation of peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0043406 // positive regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0051491 // positive regulation of filopodium assembly // inferred from sequence or structural similarity /// 0090316 // positive regulation of intracellular protein transport // inferred from sequence or structural similarity","0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from sequence or structural similarity /// 0016607 // nuclear speck // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity","0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // traceable author statement /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity","---","IPR009471 // Teneurin intracellular, N-terminal // 3.0E-37 /// IPR009471 // Teneurin intracellular, N-terminal // 3.5E-45 /// IPR013111 // EGF-like domain, extracellular // 5.1E-7 /// IPR013111 // EGF-like domain, extracellular // 2.1E-6 /// IPR013111 // EGF-like domain, extracellular // 2.5E-6 /// IPR013111 // EGF-like domain, extracellular // 1.8E-5 /// IPR013111 // EGF-like domain, extracellular // 3.6E-7 /// IPR013111 // EGF-like domain, extracellular // 9.8E-7"
"205876_at",-2.016251106,-1.723210801,-2.148484217,"DOWN","NM_002310","chr5:38479904-38595496 (-) // 99.03 // p13.1","leukemia inhibitory factor receptor alpha","LIFR","ENSG00000113594 /// OTTHUMG00000131138","3977","151443 /// 601559","NP_001121143 /// NP_002301","NM_001127671 /// NM_002310","0007166 // cell surface receptor signaling pathway // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0034097 // response to cytokine // inferred from direct assay /// 0038165 // oncostatin-M-mediated signaling pathway // inferred from direct assay /// 0048861 // leukemia inhibitory factor signaling pathway // inferred from direct assay /// 0070120 // ciliary neurotrophic factor-mediated signaling pathway // inferred from direct assay","0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004897 // ciliary neurotrophic factor receptor activity // inferred from direct assay /// 0004923 // leukemia inhibitory factor receptor activity // inferred from direct assay /// 0004924 // oncostatin-M receptor activity // inferred from direct assay /// 0005127 // ciliary neurotrophic factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from physical interaction","---","IPR003961 // Fibronectin, type III // 7.7E-10"
"205954_at",3.045527211,3.044234586,1.528513215,"UP","NM_006917","chr1:165370354-165414157 (-) // 97.99 // q23.3","retinoid X receptor, gamma","RXRG","ENSG00000143171 /// OTTHUMG00000034626","6258","180247","NP_001243499 /// NP_001243500 /// NP_008848","NM_001256570 /// NM_001256571 /// NM_006917 /// NR_033824","0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0031641 // regulation of myelination // inferred from electronic annotation /// 0032526 // response to retinoic acid // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048384 // retinoic acid receptor signaling pathway // inferred from electronic annotation","0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement","0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004886 // 9-cis retinoic acid receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","Nuclear_Receptors // GenMAPP","IPR000536 // Nuclear hormone receptor, ligand-binding, core // 1.7E-46 /// IPR001628 // Zinc finger, nuclear hormone receptor-type // 3.8E-35 /// IPR021780 // Nuclear/hormone receptor activator site AF-1 // 2.1E-36"
"206023_at",1.43245309,2.656346919,3.257729297,"UP","NM_006681","chr4:56461397-56502465 (-) // 96.57 // q12","neuromedin U","NMU","ENSG00000109255 /// OTTHUMG00000102161","10874","605103","NP_001278974 /// NP_001278975 /// NP_006672 /// XP_005265770","NM_001292045 /// NM_001292046 /// NM_006681 /// NR_120489 /// XM_005265713","0001696 // gastric acid secretion // inferred from electronic annotation /// 0006940 // regulation of smooth muscle contraction // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007586 // digestion // traceable author statement /// 0009648 // photoperiodism // inferred from electronic annotation /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0045987 // positive regulation of smooth muscle contraction // inferred from electronic annotation /// 0046887 // positive regulation of hormone secretion // inferred from electronic annotation /// 0050806 // positive regulation of synaptic transmission // inferred from electronic annotation","0005576 // extracellular region // traceable author statement /// 0043195 // terminal bouton // inferred from electronic annotation","0005102 // receptor binding // traceable author statement /// 0042922 // neuromedin U receptor binding // inferred from electronic annotation","---","IPR008200 // Neuromedin U, C-terminal // 6.2E-18 /// IPR008200 // Neuromedin U, C-terminal // 7.2E-18 /// IPR008200 // Neuromedin U, C-terminal // 5.6E-18 /// IPR008200 // Neuromedin U, C-terminal // 1.6E-15"
"206070_s_at",-1.665300833,-1.956579933,-1.336718219,"DOWN","AF213459","chr3:89156673-89531282 (+) // 98.74 // p11.1","EPH receptor A3","EPHA3","ENSG00000044524 /// OTTHUMG00000159040","2042","179611","NP_005224 /// NP_872585 /// XP_005264772 /// XP_005264773","NM_005233 /// NM_182644 /// XM_005264715 /// XM_005264716","0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0010717 // regulation of epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0010976 // positive regulation of neuron projection development // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from sequence or structural similarity /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from direct assay /// 0032956 // regulation of actin cytoskeleton organization // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0051893 // regulation of focal adhesion assembly // inferred from direct assay /// 0070507 // regulation of microtubule cytoskeleton organization // inferred from direct assay /// 0071300 // cellular response to retinoic acid // inferred from mutant phenotype /// 0097155 // fasciculation of sensory neuron axon // inferred from sequence or structural similarity /// 0097156 // fasciculation of motor neuron axon // inferred from sequence or structural similarity","0005576 // extracellular region // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005003 // ephrin receptor activity // inferred from electronic annotation /// 0005004 // GPI-linked ephrin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation","---","IPR000719 // Protein kinase domain // 3.0E-51 /// IPR001090 // Ephrin receptor ligand binding domain // 1.9E-80 /// IPR001245 // Serine-threonine/tyrosine-protein kinase catalytic domain // 5.1E-100 /// IPR003961 // Fibronectin, type III // 6.3E-18 /// IPR003961 // Fibronectin, type III // 1.7E-18 /// IPR011510 // Sterile alpha motif, type 2 // 1.4E-15 /// IPR011641 // Tyrosine-protein kinase ephrin type A/B receptor-like // 8.3E-11 /// IPR021129 // Sterile alpha motif, type 1 // 7.3E-15"
"206159_at",-1.908735544,-1.093178704,-1.415495978,"DOWN","NM_004962","chr10:48425788-48439166 (-) // 96.75 // q11.22","growth differentiation factor 10","GDF10","ENSG00000266524","2662","601361","NP_004953 /// XP_006717825","NM_004962 /// XM_006717762","0001501 // skeletal system development // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0040007 // growth // inferred from electronic annotation","0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation","0005125 // cytokine activity // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation","---","IPR001111 // Transforming growth factor-beta, N-terminal // 7.9E-9 /// IPR001839 // Transforming growth factor-beta, C-terminal // 4.7E-38"
"206201_s_at",-1.373639902,-1.224991046,-1.335367273,"DOWN","NM_005924","chr7:15650838-15726294 (-) // 92.7 // p21.2","mesenchyme homeobox 2","MEOX2","ENSG00000106511 /// OTTHUMG00000152390","4223","600535","NP_005915","NM_005924","0001525 // angiogenesis // inferred from electronic annotation /// 0001757 // somite specification // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0008015 // blood circulation // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0060021 // palate development // inferred from electronic annotation /// 0060173 // limb development // inferred from electronic annotation /// 0070997 // neuron death // inferred from mutant phenotype","0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation","0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000980 // RNA polymerase II distal enhancer sequence-specific DNA binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0001205 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001205 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from mutant phenotype /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay","---","IPR001356 // Homeobox domain // 4.9E-27"
"206214_at",-1.649583355,-1.023640783,-1.139268023,"DOWN","NM_005084","chr6:46672278-46703043 (-) // 100.0 // p12.3","phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)","PLA2G7","ENSG00000146070 /// OTTHUMG00000014789","7941","147050 /// 600807 /// 601690 /// 614278","NP_001161829 /// NP_005075 /// XP_005249465 /// XP_005249466","NM_001168357 /// NM_005084 /// XM_005249408 /// XM_005249409","0006629 // lipid metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0034374 // low-density lipoprotein particle remodeling // inferred from direct assay /// 0034440 // lipid oxidation // inferred from direct assay /// 0034441 // plasma lipoprotein particle oxidation // inferred from direct assay /// 0044267 // cellular protein metabolic process // traceable author statement /// 0050729 // positive regulation of inflammatory response // traceable author statement /// 0090026 // positive regulation of monocyte chemotaxis // inferred from direct assay","0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0034362 // low-density lipoprotein particle // inferred from direct assay","0003847 // 1-alkyl-2-acetylglycerophosphocholine esterase activity // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0047499 // calcium-independent phospholipase A2 activity // inferred from direct assay","---","IPR005065 // Platelet-activating factor acetylhydrolase // 1.3E-180"
"206315_at",1.804116061,1.787342234,1.148506108,"UP","NM_004750","chr19:18704046-18717584 (-) // 88.81 // p13.11","cytokine receptor-like factor 1","CRLF1","ENSG00000006016 /// OTTHUMG00000183111","9244","272430 /// 604237","NP_004741 /// XP_006722997","NM_004750 /// XM_006722934","0001657 // ureteric bud development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0042517 // positive regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0043524 // negative regulation of neuron apoptotic process // inferred from direct assay /// 2000672 // negative regulation of motor neuron apoptotic process // inferred from electronic annotation","0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0097058 // CRLF-CLCF1 complex // inferred from direct assay","0004872 // receptor activity // traceable author statement /// 0005125 // cytokine activity // inferred from direct assay /// 0005127 // ciliary neurotrophic factor receptor binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0019955 // cytokine binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from direct assay","---","IPR003961 // Fibronectin, type III // 7.6E-13 /// IPR015152 // Growth hormone/erythropoietin receptor, ligand binding // 4.4E-17 /// IPR015321 // Interleukin-6 receptor alpha, binding // 4.2E-11"
"206407_s_at",1.355787825,1.261933787,1.246528413,"UP","NM_005408","chr17:32683470-32685627 (+) // 98.72 // q12","chemokine (C-C motif) ligand 13","CCL13","ENSG00000181374 /// OTTHUMG00000132890","6357","601391","NP_005399","NM_005408","0006874 // cellular calcium ion homeostasis // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0008360 // regulation of cell shape // inferred from direct assay /// 0048245 // eosinophil chemotaxis // inferred from direct assay /// 0060326 // cell chemotaxis // inferred from electronic annotation","0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation","0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from direct assay","---","IPR001811 // Chemokine interleukin-8-like domain // 2.8E-28 /// IPR001811 // Chemokine interleukin-8-like domain // 1.4E-19"
"206457_s_at",-3.948759062,-3.225852902,-3.676181794,"DOWN","NM_000792","chr1:54359877-54376758 (+) // 99.51 // p32.3","deiodinase, iodothyronine, type I","DIO1","ENSG00000211452 /// OTTHUMG00000008435","1733","147892","NP_000783 /// NP_001034804 /// NP_001034805 /// NP_998758","NM_000792 /// NM_001039715 /// NM_001039716 /// NM_213593","0006590 // thyroid hormone generation // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation","0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0004800 // thyroxine 5'-deiodinase activity // inferred from electronic annotation /// 0008430 // selenium binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation","---","IPR000643 // Iodothyronine deiodinase // 2.5E-109 /// IPR000643 // Iodothyronine deiodinase // 7.3E-62 /// IPR000643 // Iodothyronine deiodinase // 1.8E-107 /// IPR000643 // Iodothyronine deiodinase // 5.2E-60"
"206461_x_at",-1.119796751,-1.083541312,-1.009377842,"DOWN","NM_005951","chr16:56703773-56705040 (+) // 94.01 // q13","metallothionein 1H","MT1H","ENSG00000205358 /// OTTHUMG00000133283","4496","156354","NP_005942","NM_005951","0045926 // negative regulation of growth // inferred from sequence or structural similarity /// 0071276 // cellular response to cadmium ion // inferred from expression pattern /// 0071294 // cellular response to zinc ion // inferred from expression pattern","0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity","0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR003019 // Metallothionein superfamily, eukaryotic // 2.0E-17 /// IPR003019 // Metallothionein superfamily, eukaryotic // 1.2E-11"
"206517_at",-3.044337397,-2.386509974,-3.92592886,"DOWN","NM_004062","chr16:66942058-66951982 (-) // 99.13 // q22.1","cadherin 16, KSP-cadherin","CDH16","ENSG00000166589 /// OTTHUMG00000137518","1014","603118","NP_001191673 /// NP_001191674 /// NP_001191675 /// NP_004053 /// XP_005255825 /// XP_005255826 /// XP_005255827","NM_001204744 /// NM_001204745 /// NM_001204746 /// NM_004062 /// XM_005255768 /// XM_005255769 /// XM_005255770","0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation","0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR002126 // Cadherin // 5.4E-11 /// IPR002126 // Cadherin // 4.6E-11 /// IPR002126 // Cadherin // 1.2E-14 /// IPR002126 // Cadherin // 5.8E-12 /// IPR002126 // Cadherin // 5.6E-11 /// IPR002126 // Cadherin // 4.8E-11 /// IPR002126 // Cadherin // 1.3E-14 /// IPR002126 // Cadherin // 6.0E-12 /// IPR002126 // Cadherin // 4.1E-11 /// IPR002126 // Cadherin // 1.0E-14 /// IPR002126 // Cadherin // 5.0E-12 /// IPR002126 // Cadherin // 4.8E-11 /// IPR002126 // Cadherin // 4.2E-11 /// IPR002126 // Cadherin // 1.1E-14 /// IPR002126 // Cadherin // 5.2E-12 /// IPR002126 // Cadherin // 5.2E-11 /// IPR002126 // Cadherin // 4.5E-11 /// IPR002126 // Cadherin // 5.6E-12 /// IPR002126 // Cadherin // 3.4E-11"
"206529_x_at",-2.459697692,-1.919854666,-2.915308468,"DOWN","NM_000441","chr7:107301079-107358250 (+) // 91.74 // q22.3","solute carrier family 26 (anion exchanger), member 4","SLC26A4","ENSG00000091137 /// OTTHUMG00000154807","5172","274600 /// 600791 /// 605646","NP_000432 /// XP_005250482 /// XP_005250483 /// XP_006716087 /// XP_006716088","NM_000441 /// XM_005250425 /// XM_005250426 /// XM_006716024 /// XM_006716025","0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006821 // chloride transport // inferred from electronic annotation /// 0006885 // regulation of pH // inferred from sequence or structural similarity /// 0007605 // sensory perception of sound // traceable author statement /// 0008272 // sulfate transport // traceable author statement /// 0015698 // inorganic anion transport // traceable author statement /// 0015705 // iodide transport // inferred from electronic annotation /// 0032880 // regulation of protein localization // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 1902358 // sulfate transmembrane transport // inferred from electronic annotation /// 1902358 // sulfate transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // traceable author statement","0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0031526 // brush border membrane // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0008271 // secondary active sulfate transmembrane transporter activity // inferred from electronic annotation /// 0015108 // chloride transmembrane transporter activity // inferred from electronic annotation /// 0015111 // iodide transmembrane transporter activity // inferred from electronic annotation /// 0015116 // sulfate transmembrane transporter activity // traceable author statement","---","IPR002645 // STAS domain // 3.6E-46 /// IPR011547 // Sulphate transporter // 4.6E-75"
"206714_at",1.699198847,1.640622425,1.890656287,"UP","NM_001141","chr17:7942401-7952449 (+) // 93.74 // p13.1","arachidonate 15-lipoxygenase, type B","ALOX15B","ENSG00000179593 /// OTTHUMG00000108181","247","603697","NP_001034219 /// NP_001034220 /// NP_001132","NM_001039130 /// NM_001039131 /// NM_001141","0006629 // lipid metabolic process // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010744 // positive regulation of macrophage derived foam cell differentiation // inferred from mutant phenotype /// 0019369 // arachidonic acid metabolic process // inferred from direct assay /// 0019369 // arachidonic acid metabolic process // traceable author statement /// 0019372 // lipoxygenase pathway // traceable author statement /// 0030336 // negative regulation of cell migration // traceable author statement /// 0030850 // prostate gland development // non-traceable author statement /// 0030856 // regulation of epithelial cell differentiation // non-traceable author statement /// 0035360 // positive regulation of peroxisome proliferator activated receptor signaling pathway // inferred from electronic annotation /// 0043651 // linoleic acid metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045618 // positive regulation of keratinocyte differentiation // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0045926 // negative regulation of growth // inferred from direct assay /// 0051122 // hepoxilin biosynthetic process // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0090197 // positive regulation of chemokine secretion // inferred from mutant phenotype","0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0019898 // extrinsic component of membrane // inferred from direct assay","0005506 // iron ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0016165 // linoleate 13S-lipoxygenase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016702 // oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen // inferred from electronic annotation /// 0036403 // arachidonate 8(S)-lipoxygenase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050473 // arachidonate 15-lipoxygenase activity // inferred from direct assay /// 0051213 // dioxygenase activity // inferred from electronic annotation","Eicosanoid_Synthesis // GenMAPP","IPR001024 // PLAT/LH2 domain // 1.1E-27 /// IPR001024 // PLAT/LH2 domain // 9.8E-28 /// IPR013819 // Lipoxygenase, C-terminal // 1.4E-121 /// IPR013819 // Lipoxygenase, C-terminal // 1.7E-44 /// IPR013819 // Lipoxygenase, C-terminal // 1.8E-60"
"206765_at",3.511116181,2.519583743,2.511825144,"UP","AF153820","chr17:68165675-68176181 (+) // 97.63 // q24.3","potassium inwardly-rectifying channel, subfamily J, member 2","KCNJ2","ENSG00000123700 /// OTTHUMG00000180351","3759","170390 /// 600681 /// 609622 /// 613980","NP_000882","NM_000891","0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from direct assay /// 0007268 // synaptic transmission // traceable author statement /// 0010107 // potassium ion import // inferred from direct assay /// 0014861 // regulation of skeletal muscle contraction via regulation of action potential // inferred from mutant phenotype /// 0015693 // magnesium ion transport // inferred from electronic annotation /// 0030007 // cellular potassium ion homeostasis // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from direct assay /// 0055119 // relaxation of cardiac muscle // inferred from mutant phenotype /// 0060075 // regulation of resting membrane potential // traceable author statement /// 0060306 // regulation of membrane repolarization // inferred from direct assay /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from direct assay /// 0086001 // cardiac muscle cell action potential // inferred from electronic annotation /// 0086002 // cardiac muscle cell action potential involved in contraction // inferred from mutant phenotype /// 0086004 // regulation of cardiac muscle cell contraction // inferred from electronic annotation /// 0086011 // membrane repolarization during action potential // inferred from mutant phenotype /// 0086012 // membrane depolarization during cardiac muscle cell action potential // traceable author statement /// 0086013 // membrane repolarization during cardiac muscle cell action potential // inferred from mutant phenotype /// 0086013 // membrane repolarization during cardiac muscle cell action potential // traceable author statement /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 0090076 // relaxation of skeletal muscle // inferred from mutant phenotype /// 1901381 // positive regulation of potassium ion transmembrane transport // inferred from electronic annotation","0005790 // smooth endoplasmic reticulum // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from direct assay /// 0014704 // intercalated disc // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031224 // intrinsic component of membrane // inferred from direct assay /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043197 // dendritic spine // inferred from electronic annotation","0005242 // inward rectifier potassium channel activity // inferred from direct assay /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005546 // phosphatidylinositol-4,5-bisphosphate binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from electronic annotation /// 0086008 // voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization // inferred from mutant phenotype","---","IPR013673 // Potassium channel, inwardly rectifying, Kir, N-terminal // 4.2E-33 /// IPR016449 // Potassium channel, inwardly rectifying, Kir // 4.4E-174"
"206806_at",-2.984710312,-1.575357136,-2.575588408,"DOWN","NM_004717","chr7:137074384-138037046 (-) // 89.79 // q33","diacylglycerol kinase, iota","DGKI","ENSG00000157680 /// OTTHUMG00000155697","9162","604072","NP_004708 /// XP_006716235 /// XP_006716236 /// XP_006716237","NM_004717 /// XM_006716172 /// XM_006716173 /// XM_006716174","0007205 // protein kinase C-activating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032317 // regulation of Rap GTPase activity // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0046579 // positive regulation of Ras protein signal transduction // inferred from electronic annotation","0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0032045 // guanyl-nucleotide exchange factor complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation","0000166 // nucleotide binding // inferred from electronic annotation /// 0003951 // NAD+ kinase activity // inferred from electronic annotation /// 0004143 // diacylglycerol kinase activity // inferred from electronic annotation /// 0005095 // GTPase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0017016 // Ras GTPase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000756 // Diacylglycerol kinase, accessory domain // 1.3E-50 /// IPR001206 // Diacylglycerol kinase, catalytic domain // 4.3E-37 /// IPR002110 // Ankyrin repeat // 6.2E-9"
"206884_s_at",3.456426302,2.969425417,2.396293504,"UP","NM_003843","chr13:78109893-78218643 (+) // 98.98 // q22.3","sciellin","SCEL","ENSG00000136155 /// OTTHUMG00000017107","8796","604112","NP_001154178 /// NP_003834 /// NP_659001 /// XP_005266635 /// XP_006719945 /// XP_006719946 /// XP_006719947 /// XP_006719948 /// XP_006719949","NM_001160706 /// NM_003843 /// NM_144777 /// XM_005266578 /// XM_006719882 /// XM_006719883 /// XM_006719884 /// XM_006719885 /// XM_006719886","0008544 // epidermis development // inferred from sequence or structural similarity /// 0008544 // epidermis development // traceable author statement /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0030216 // keratinocyte differentiation // inferred from direct assay","0001533 // cornified envelope // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","---"
"207144_s_at",3.229457735,3.84601278,3.697863374,"UP","NM_004143","chrX:71521496-71527004 (-) // 98.24 // q13.1","Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1","CITED1","ENSG00000125931 /// OTTHUMG00000021812","4435","300149","NP_001138357 /// NP_001138358 /// NP_001138359 /// NP_004134 /// XP_005262323 /// XP_005262324","NM_001144885 /// NM_001144886 /// NM_001144887 /// NM_004143 /// XM_005262266 /// XM_005262267","0000578 // embryonic axis specification // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001656 // metanephros development // traceable author statement /// 0001658 // branching involved in ureteric bud morphogenesis // inferred from sequence or structural similarity /// 0001890 // placenta development // inferred from sequence or structural similarity /// 0003340 // negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // traceable author statement /// 0030318 // melanocyte differentiation // inferred from mutant phenotype /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0032868 // response to insulin // inferred from sequence or structural similarity /// 0034097 // response to cytokine // inferred from sequence or structural similarity /// 0034341 // response to interferon-gamma // inferred from sequence or structural similarity /// 0042438 // melanin biosynthetic process // inferred from sequence or structural similarity /// 0043473 // pigmentation // inferred from mutant phenotype /// 0043524 // negative regulation of neuron apoptotic process // inferred from direct assay /// 0043627 // response to estrogen // inferred from direct assay /// 0043627 // response to estrogen // traceable author statement /// 0045668 // negative regulation of osteoblast differentiation // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0051591 // response to cAMP // inferred from sequence or structural similarity /// 0060231 // mesenchymal to epithelial transition // traceable author statement /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0060711 // labyrinthine layer development // inferred from electronic annotation /// 0060712 // spongiotrophoblast layer development // inferred from electronic annotation /// 0070555 // response to interleukin-1 // inferred from sequence or structural similarity /// 0070669 // response to interleukin-2 // inferred from sequence or structural similarity /// 0070670 // response to interleukin-4 // inferred from sequence or structural similarity /// 0070741 // response to interleukin-6 // inferred from sequence or structural similarity /// 0071104 // response to interleukin-9 // inferred from sequence or structural similarity /// 0071105 // response to interleukin-11 // inferred from sequence or structural similarity /// 0071107 // response to parathyroid hormone // inferred from sequence or structural similarity /// 0071559 // response to transforming growth factor beta // inferred from direct assay","0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay","0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0050693 // LBD domain binding // inferred from direct assay /// 0070410 // co-SMAD binding // inferred from physical interaction","---","IPR007576 // CITED // 4.9E-65 /// IPR007576 // CITED // 3.0E-65"
"207415_at",-2.110463258,-1.238195479,-1.227966511,"DOWN","NM_007366","chr2:160802863-160919121 (-) // 98.49 // q24.2","phospholipase A2 receptor 1, 180kDa","PLA2R1","ENSG00000153246 /// OTTHUMG00000154087","22925","604939","NP_001007268 /// NP_001182570 /// NP_031392 /// XP_005246449 /// XP_005246450 /// XP_005246452 /// XP_006712432","NM_001007267 /// NM_001195641 /// NM_007366 /// XM_005246392 /// XM_005246393 /// XM_005246395 /// XM_006712369","0001816 // cytokine production // inferred from mutant phenotype /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0043517 // positive regulation of DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype /// 0072593 // reactive oxygen species metabolic process // inferred from direct assay /// 0090238 // positive regulation of arachidonic acid secretion // inferred from sequence or structural similarity /// 0090399 // replicative senescence // inferred from mutant phenotype /// 0090403 // oxidative stress-induced premature senescence // inferred from mutant phenotype /// 1900138 // negative regulation of phospholipase A2 activity // inferred from sequence or structural similarity /// 1900139 // negative regulation of arachidonic acid secretion // inferred from sequence or structural similarity","0005576 // extracellular region // inferred from sequence or structural similarity /// 0005576 // extracellular region // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0004872 // receptor activity // inferred from direct assay /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0043274 // phospholipase binding // inferred from electronic annotation /// 0043274 // phospholipase binding // inferred from physical interaction","---","IPR000562 // Fibronectin, type II, collagen-binding // 8.1E-22 /// IPR001304 // C-type lectin // 3.3E-25 /// IPR001304 // C-type lectin // 8.9E-23 /// IPR001304 // C-type lectin // 2.2E-16 /// IPR001304 // C-type lectin // 3.7E-18 /// IPR001304 // C-type lectin // 3.9E-20 /// IPR001304 // C-type lectin // 7.4E-18 /// IPR001304 // C-type lectin // 2.7E-19 /// IPR008646 // Herpesvirus UL45-like // 4.3E-8"
"207691_x_at",2.871792936,2.283270978,1.849875615,"UP","NM_001776","chr10:97515929-97626359 (+) // 99.89 // q24.1","ectonucleoside triphosphate diphosphohydrolase 1","ENTPD1","ENSG00000138185 /// OTTHUMG00000018818","953","601752 /// 615683","NP_001091645 /// NP_001157650 /// NP_001157651 /// NP_001157653 /// NP_001157654 /// NP_001157655 /// NP_001767 /// XP_006718139 /// XP_006718140","NM_001098175 /// NM_001164178 /// NM_001164179 /// NM_001164181 /// NM_001164182 /// NM_001164183 /// NM_001776 /// XM_006718076 /// XM_006718077","0006200 // ATP catabolic process // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009181 // purine ribonucleoside diphosphate catabolic process // inferred from electronic annotation /// 0030168 // platelet activation // inferred from electronic annotation","0005605 // basal lamina // inferred from electronic annotation /// 0005886 // plasma membrane // non-traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017110 // nucleoside-diphosphatase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation","---","IPR000407 // Nucleoside phosphatase GDA1/CD39 // 7.7E-162 /// IPR000407 // Nucleoside phosphatase GDA1/CD39 // 7.4E-162 /// IPR000407 // Nucleoside phosphatase GDA1/CD39 // 8.0E-162 /// IPR000407 // Nucleoside phosphatase GDA1/CD39 // 2.4E-133 /// IPR000407 // Nucleoside phosphatase GDA1/CD39 // 2.3E-115"
"207695_s_at",2.274160213,2.936728596,2.256299377,"UP","NM_001555","chrX:130407482-130420715 (-) // 99.43 // q26.2","immunoglobulin superfamily, member 1","IGSF1","ENSG00000147255 /// OTTHUMG00000022406","3547","300137 /// 300888","NP_001164432 /// NP_001164433 /// NP_001164434 /// NP_001546 /// NP_991402 /// XP_006724818 /// XP_006724819","NM_001170961 /// NM_001170962 /// NM_001170963 /// NM_001555 /// NM_205833 /// XM_006724755 /// XM_006724756","0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0007165 // signal transduction // inferred from direct assay","0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation","0004872 // receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0015026 // coreceptor activity // inferred from electronic annotation /// 0034711 // inhibin binding // inferred from direct assay","---","IPR013151 // Immunoglobulin // 2.1E-8 /// IPR013151 // Immunoglobulin // 2.1E-8"
"207789_s_at",-2.397610005,-1.326293248,-1.65402566,"DOWN","NM_001936","chr7:154002402-154685161 (+) // 98.62 // q36.2","dipeptidyl-peptidase 6","DPP6","ENSG00000130226 /// OTTHUMG00000151511","1804","126141 /// 612956","NP_001034439 /// NP_001277181 /// NP_001277182 /// NP_001927 /// NP_570629 /// XP_006715934 /// XP_006715935","NM_001039350 /// NM_001290252 /// NM_001290253 /// NM_001936 /// NM_130797 /// XM_006715871 /// XM_006715872","0006508 // proteolysis // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0019228 // neuronal action potential // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0043266 // regulation of potassium ion transport // inferred from electronic annotation","0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0004177 // aminopeptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0008239 // dipeptidyl-peptidase activity // traceable author statement","---","IPR001375 // Peptidase S9, prolyl oligopeptidase, catalytic domain // 8.8E-42 /// IPR002469 // Peptidase S9B, dipeptidylpeptidase IV N-terminal // 1.2E-116 /// IPR011659 // WD40-like Beta Propeller // 5.8E-6"
"207808_s_at",2.346191794,2.495199052,2.30150041,"UP","NM_000313","chr3:93591956-93692705 (-) // 98.49 // q11.1","protein S (alpha)","PROS1","ENSG00000184500 /// OTTHUMG00000150354","5627","176880 /// 612336 /// 614514","NP_000304 /// XP_005247683","NM_000313 /// XM_005247626","0002576 // platelet degranulation // traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement /// 0017187 // peptidyl-glutamic acid carboxylation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030449 // regulation of complement activation // traceable author statement /// 0042730 // fibrinolysis // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050900 // leukocyte migration // traceable author statement","0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005796 // Golgi lumen // traceable author statement /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay","0004866 // endopeptidase inhibitor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation","---","IPR000294 // Gamma-carboxyglutamic acid-rich (GLA) domain // 9.3E-19 /// IPR000742 // Epidermal growth factor-like domain // 2.3E-8 /// IPR001791 // Laminin G domain // 1.2E-31 /// IPR001791 // Laminin G domain // 7.8E-15 /// IPR001791 // Laminin G domain // 5.4E-12 /// IPR001791 // Laminin G domain // 6.8E-32 /// IPR001791 // Laminin G domain // 4.3E-15 /// IPR001791 // Laminin G domain // 3.0E-12 /// IPR001881 // EGF-like calcium-binding domain // 5.6E-9 /// IPR001881 // EGF-like calcium-binding domain // 5.7E-12 /// IPR001881 // EGF-like calcium-binding domain // 3.4E-9 /// IPR001881 // EGF-like calcium-binding domain // 3.5E-12"
"207847_s_at",1.203355775,1.3802556,2.000884623,"UP","NM_002456","chr1:155158540-155162680 (-) // 91.28 // q22","mucin 1, cell surface associated","MUC1","ENSG00000185499 /// OTTHUMG00000035681","4582","158340 /// 174000","NP_001018016 /// NP_001018017 /// NP_001037855 /// NP_001037856 /// NP_001037857 /// NP_001037858 /// NP_001191214 /// NP_001191215 /// NP_001191216 /// NP_001191217 /// NP_001191218 /// NP_001191219 /// NP_001191220 /// NP_001191221 /// NP_001191222 /// NP_001191223 /// NP_001191224 /// NP_001191225 /// NP_001191226 /// NP_002447","NM_001018016 /// NM_001018017 /// NM_001018021 /// NM_001044390 /// NM_001044391 /// NM_001044392 /// NM_001044393 /// NM_001204285 /// NM_001204286 /// NM_001204287 /// NM_001204288 /// NM_001204289 /// NM_001204290 /// NM_001204291 /// NM_001204292 /// NM_001204293 /// NM_001204294 /// NM_001204295 /// NM_001204296 /// NM_001204297 /// NM_002456 /// NM_182741","0001666 // response to hypoxia // inferred from electronic annotation /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from direct assay /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from direct assay /// 0007565 // female pregnancy // inferred from electronic annotation /// 0010944 // negative regulation of transcription by competitive promoter binding // inferred from direct assay /// 0016266 // O-glycan processing // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0036003 // positive regulation of transcription from RNA polymerase II promoter in response to stress // inferred from direct assay /// 0043618 // regulation of transcription from RNA polymerase II promoter in response to stress // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0090240 // positive regulation of histone H4 acetylation // inferred from direct assay /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay","0000790 // nuclear chromatin // inferred from direct assay /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0002039 // p53 binding // inferred from physical interaction /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction","---","IPR000082 // SEA domain // 1.3E-19 /// IPR000082 // SEA domain // 9.4E-10 /// IPR000082 // SEA domain // 8.8E-25 /// IPR000082 // SEA domain // 1.2E-19 /// IPR000082 // SEA domain // 1.9E-24 /// IPR000082 // SEA domain // 5.3E-24"
"207980_s_at",-2.313799787,-1.90958285,-2.000849555,"DOWN","NM_006079","chr6:139694210-139695742 (-) // 99.89 // q24.1","Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2","CITED2","ENSG00000164442 /// OTTHUMG00000015691","10370","602937 /// 614431 /// 614433","NP_001161860 /// NP_001161861 /// NP_006070","NM_001168388 /// NM_001168389 /// NM_006079","0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from direct assay /// 0001666 // response to hypoxia // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001829 // trophectodermal cell differentiation // inferred from electronic annotation /// 0001841 // neural tube formation // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0001889 // liver development // inferred from sequence or structural similarity /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0001944 // vasculature development // inferred from electronic annotation /// 0001947 // heart looping // inferred from electronic annotation /// 0002089 // lens morphogenesis in camera-type eye // inferred from electronic annotation /// 0002244 // hematopoietic progenitor cell differentiation // inferred from electronic annotation /// 0002521 // leukocyte differentiation // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003156 // regulation of organ formation // inferred from sequence or structural similarity /// 0003197 // endocardial cushion development // inferred from electronic annotation /// 0003281 // ventricular septum development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from sequence or structural similarity /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from mutant phenotype /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007530 // sex determination // inferred from sequence or structural similarity /// 0007569 // cell aging // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0008584 // male gonad development // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0021602 // cranial nerve morphogenesis // inferred from electronic annotation /// 0022409 // positive regulation of cell-cell adhesion // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from sequence or structural similarity /// 0030851 // granulocyte differentiation // inferred from electronic annotation /// 0034405 // response to fluid shear stress // inferred from mutant phenotype /// 0035360 // positive regulation of peroxisome proliferator activated receptor signaling pathway // inferred from direct assay /// 0035802 // adrenal cortex formation // inferred from sequence or structural similarity /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043627 // response to estrogen // inferred from direct assay /// 0045787 // positive regulation of cell cycle // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046697 // decidualization // inferred from electronic annotation /// 0048536 // spleen development // inferred from sequence or structural similarity /// 0048538 // thymus development // inferred from electronic annotation /// 0048596 // embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0060136 // embryonic process involved in female pregnancy // inferred from electronic annotation /// 0060349 // bone morphogenesis // inferred from electronic annotation /// 0060411 // cardiac septum morphogenesis // inferred from electronic annotation /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0060971 // embryonic heart tube left/right pattern formation // inferred from sequence or structural similarity /// 0061156 // pulmonary artery morphogenesis // inferred from electronic annotation /// 0061308 // cardiac neural crest cell development involved in heart development // inferred from electronic annotation /// 0061371 // determination of heart left/right asymmetry // inferred from electronic annotation /// 0061428 // negative regulation of transcription from RNA polymerase II promoter in response to hypoxia // inferred from direct assay /// 0070986 // left/right axis specification // inferred from sequence or structural similarity /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 1900164 // nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry // inferred from sequence or structural similarity /// 2000020 // positive regulation of male gonad development // inferred from sequence or structural similarity /// 2001141 // regulation of RNA biosynthetic process // inferred from direct assay","0000790 // nuclear chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from mutant phenotype","0001102 // RNA polymerase II activating transcription factor binding // inferred from electronic annotation /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from electronic annotation /// 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0035035 // histone acetyltransferase binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0050693 // LBD domain binding // inferred from physical interaction","---","IPR007576 // CITED // 2.2E-36 /// IPR007576 // CITED // 1.2E-49"
"207981_s_at",-1.928989567,-1.446693653,-2.119668471,"DOWN","NM_001438","chr1:216676593-217262947 (-) // 93.18 // q41","estrogen-related receptor gamma","ESRRG","ENSG00000196482 /// OTTHUMG00000037025","2104","602969","NP_001127757 /// NP_001230434 /// NP_001230435 /// NP_001230436 /// NP_001230438 /// NP_001230439 /// NP_001230440 /// NP_001230441 /// NP_001230442 /// NP_001230443 /// NP_001230444 /// NP_001230447 /// NP_001230448 /// NP_001429 /// NP_996317 /// NP_996318 /// XP_006711266 /// XP_006711267 /// XP_006711268 /// XP_006711269 /// XP_006711270 /// XP_006711271 /// XP_006711272","NM_001134285 /// NM_001243505 /// NM_001243506 /// NM_001243507 /// NM_001243509 /// NM_001243510 /// NM_001243511 /// NM_001243512 /// NM_001243513 /// NM_001243514 /// NM_001243515 /// NM_001243518 /// NM_001243519 /// NM_001438 /// NM_206594 /// NM_206595 /// XM_006711203 /// XM_006711204 /// XM_006711205 /// XM_006711206 /// XM_006711207 /// XM_006711208 /// XM_006711209","0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048384 // retinoic acid receptor signaling pathway // inferred from electronic annotation","0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement","0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003708 // retinoic acid receptor activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050682 // AF-2 domain binding // inferred from sequence or structural similarity","---","IPR000536 // Nuclear hormone receptor, ligand-binding, core // 3.9E-40 /// IPR000536 // Nuclear hormone receptor, ligand-binding, core // 4.6E-40 /// IPR000536 // Nuclear hormone receptor, ligand-binding, core // 4.4E-40 /// IPR000536 // Nuclear hormone receptor, ligand-binding, core // 4.0E-40 /// IPR001628 // Zinc finger, nuclear hormone receptor-type // 1.4E-34 /// IPR001628 // Zinc finger, nuclear hormone receptor-type // 1.6E-34 /// IPR001628 // Zinc finger, nuclear hormone receptor-type // 1.5E-34"
"208025_s_at",5.255380577,3.239436926,3.060414808,"UP","NM_003483","chr12:66217910-66360075 (+) // 86.49 // q14.3","high mobility group AT-hook 2","HMGA2","ENSG00000149948 /// OTTHUMG00000168936","8091","150699 /// 600698","NP_003474 /// NP_003475 /// XP_005269221 /// XP_006719683","NM_001015886 /// NM_003483 /// NM_003484 /// XM_005269164 /// XM_006719620 /// XR_245958","0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000737 // DNA catabolic process, endonucleolytic // inferred from direct assay /// 0001837 // epithelial to mesenchymal transition // inferred from mutant phenotype /// 0002062 // chondrocyte differentiation // inferred from direct assay /// 0003131 // mesodermal-endodermal cell signaling // inferred from mutant phenotype /// 0006284 // base-excision repair // inferred from direct assay /// 0006325 // chromatin organization // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007095 // mitotic G2 DNA damage checkpoint // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009615 // response to virus // inferred from expression pattern /// 0010564 // regulation of cell cycle process // inferred from direct assay /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0021846 // cell proliferation in forebrain // inferred from electronic annotation /// 0021983 // pituitary gland development // inferred from electronic annotation /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0031052 // chromosome breakage // inferred from direct assay /// 0031507 // heterochromatin assembly // inferred from direct assay /// 0033144 // negative regulation of intracellular steroid hormone receptor signaling pathway // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0035978 // histone H2A-S139 phosphorylation // inferred from direct assay /// 0035986 // senescence-associated heterochromatin focus assembly // inferred from direct assay /// 0035987 // endodermal cell differentiation // inferred from mutant phenotype /// 0035988 // chondrocyte proliferation // inferred from direct assay /// 0040008 // regulation of growth // inferred from electronic annotation /// 0040018 // positive regulation of multicellular organism growth // inferred from electronic annotation /// 0042769 // DNA damage response, detection of DNA damage // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043392 // negative regulation of DNA binding // inferred from direct assay /// 0043922 // negative regulation by host of viral transcription // inferred from direct assay /// 0045444 // fat cell differentiation // inferred from mutant phenotype /// 0045869 // negative regulation of single stranded viral RNA replication via double stranded DNA intermediate // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046426 // negative regulation of JAK-STAT cascade // inferred from electronic annotation /// 0048333 // mesodermal cell differentiation // inferred from mutant phenotype /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0048762 // mesenchymal cell differentiation // inferred from mutant phenotype /// 0048863 // stem cell differentiation // inferred from expression pattern /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0060123 // regulation of growth hormone secretion // inferred from electronic annotation /// 0060612 // adipose tissue development // inferred from electronic annotation /// 0060613 // fat pad development // inferred from electronic annotation /// 0071158 // positive regulation of cell cycle arrest // inferred from direct assay /// 0090276 // regulation of peptide hormone secretion // inferred from electronic annotation /// 0090402 // oncogene-induced cell senescence // inferred from direct assay /// 2000036 // regulation of stem cell maintenance // inferred from mutant phenotype /// 2000036 // regulation of stem cell maintenance // traceable author statement /// 2000648 // positive regulation of stem cell proliferation // inferred from direct assay /// 2000648 // positive regulation of stem cell proliferation // inferred from mutant phenotype /// 2000679 // positive regulation of transcription regulatory region DNA binding // inferred from direct assay /// 2000685 // positive regulation of cellular response to X-ray // inferred from direct assay /// 2000774 // positive regulation of cellular senescence // inferred from mutant phenotype /// 2001022 // positive regulation of response to DNA damage stimulus // inferred from direct assay /// 2001033 // negative regulation of double-strand break repair via nonhomologous end joining // inferred from direct assay /// 2001038 // regulation of cellular response to drug // inferred from direct assay","0000228 // nuclear chromosome // inferred from sequence or structural similarity /// 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0032993 // protein-DNA complex // inferred from direct assay /// 0035985 // senescence-associated heterochromatin focus // inferred from direct assay /// 0071141 // SMAD protein complex // inferred from direct assay","0000975 // regulatory region DNA binding // inferred from direct assay /// 0000988 // protein binding transcription factor activity // inferred from direct assay /// 0001047 // core promoter binding // inferred from direct assay /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from direct assay /// 0001078 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription // inferred from direct assay /// 0003677 // DNA binding // non-traceable author statement /// 0003680 // AT DNA binding // inferred from direct assay /// 0003680 // AT DNA binding // inferred from mutant phenotype /// 0003906 // DNA-(apurinic or apyrimidinic site) lyase activity // inferred from direct assay /// 0004677 // DNA-dependent protein kinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008301 // DNA binding, bending // inferred from direct assay /// 0008301 // DNA binding, bending // inferred from mutant phenotype /// 0019899 // enzyme binding // inferred from electronic annotation /// 0031492 // nucleosomal DNA binding // inferred from direct assay /// 0035497 // cAMP response element binding // inferred from direct assay /// 0035500 // MH2 domain binding // inferred from direct assay /// 0035501 // MH1 domain binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from physical interaction /// 0051575 // 5'-deoxyribose-5-phosphate lyase activity // inferred from direct assay /// 0070742 // C2H2 zinc finger domain binding // inferred from mutant phenotype","---","IPR017956 // AT hook, DNA-binding motif // 2.0E-7 /// IPR017956 // AT hook, DNA-binding motif // 7.3E-7"
"208161_s_at",2.11345273,1.973890167,2.653954933,"UP","NM_020037","chr17:48712227-48769062 (+) // 97.26 // q21.33","ATP-binding cassette, sub-family C (CFTR/MRP), member 3","ABCC3","ENSG00000108846 /// OTTHUMG00000162245","8714","604323","NP_001137542 /// NP_003777 /// XP_005257820","NM_001144070 /// NM_003786 /// NM_020037 /// NM_020038 /// XM_005257763","0006200 // ATP catabolic process // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // traceable author statement /// 0015721 // bile acid and bile salt transport // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // traceable author statement","0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation","0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008514 // organic anion transmembrane transporter activity // traceable author statement /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation","---","IPR001140 // ABC transporter, transmembrane domain // 3.3E-42 /// IPR001140 // ABC transporter, transmembrane domain // 5.7E-44 /// IPR001140 // ABC transporter, transmembrane domain // 2.3E-42 /// IPR001140 // ABC transporter, transmembrane domain // 2.2E-37 /// IPR003439 // ABC transporter-like // 1.2E-18 /// IPR003439 // ABC transporter-like // 1.7E-20 /// IPR003439 // ABC transporter-like // 9.4E-19"
"208228_s_at",-2.19669221,-1.54913295,-1.227316535,"DOWN","M87771","chr10:123238731-123357812 (-) // 97.84 // q26.13","fibroblast growth factor receptor 2","FGFR2","ENSG00000066468 /// OTTHUMG00000019175","2263","101200 /// 101400 /// 101600 /// 123150 /// 123500 /// 123790 /// 149730 /// 176943 /// 207410 /// 609579 /// 613659 /// 614592","NP_000132 /// NP_001138385 /// NP_001138386 /// NP_001138387 /// NP_001138388 /// NP_001138389 /// NP_001138390 /// NP_001138391 /// NP_075259 /// NP_075418 /// XP_006717771 /// XP_006717772 /// XP_006717773 /// XP_006717774 /// XP_006717775 /// XP_006717776","NM_000141 /// NM_001144913 /// NM_001144914 /// NM_001144915 /// NM_001144916 /// NM_001144917 /// NM_001144918 /// NM_001144919 /// NM_022970 /// NM_022971 /// NM_022972 /// NM_022973 /// NM_022974 /// NM_022975 /// NM_022976 /// NM_023028 /// NM_023029 /// NM_023030 /// NR_073009 /// XM_006717708 /// XM_006717709 /// XM_006717710 /// XM_006717711 /// XM_006717712 /// XM_006717713","0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from sequence or structural similarity /// 0001657 // ureteric bud development // inferred from sequence or structural similarity /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001837 // epithelial to mesenchymal transition // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0003148 // outflow tract septum morphogenesis // inferred from sequence or structural similarity /// 0003149 // membranous septum morphogenesis // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // inferred from sequence or structural similarity /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0007528 // neuromuscular junction development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from genetic interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from physical interaction /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0008589 // regulation of smoothened signaling pathway // inferred from sequence or structural similarity /// 0009791 // post-embryonic development // inferred from sequence or structural similarity /// 0009880 // embryonic pattern specification // inferred from sequence or structural similarity /// 0009887 // organ morphogenesis // inferred from sequence or structural similarity /// 0010453 // regulation of cell fate commitment // inferred from sequence or structural similarity /// 0010518 // positive regulation of phospholipase activity // inferred from mutant phenotype /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from sequence or structural similarity /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021769 // orbitofrontal cortex development // inferred from sequence or structural similarity /// 0021847 // ventricular zone neuroblast division // inferred from sequence or structural similarity /// 0021860 // pyramidal neuron development // inferred from sequence or structural similarity /// 0022612 // gland morphogenesis // inferred from sequence or structural similarity /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030282 // bone mineralization // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from sequence or structural similarity /// 0030855 // epithelial cell differentiation // inferred from sequence or structural similarity /// 0030901 // midbrain development // inferred from sequence or structural similarity /// 0030916 // otic vesicle formation // inferred from sequence or structural similarity /// 0031069 // hair follicle morphogenesis // inferred from sequence or structural similarity /// 0032808 // lacrimal gland development // inferred from sequence or structural similarity /// 0033688 // regulation of osteoblast proliferation // traceable author statement /// 0035264 // multicellular organism growth // inferred from sequence or structural similarity /// 0035265 // organ growth // inferred from sequence or structural similarity /// 0035602 // fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow // inferred from sequence or structural similarity /// 0035603 // fibroblast growth factor receptor signaling pathway involved in hemopoiesis // inferred from sequence or structural similarity /// 0035604 // fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow // inferred from sequence or structural similarity /// 0035607 // fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0040014 // regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040036 // regulation of fibroblast growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from sequence or structural similarity /// 0042476 // odontogenesis // inferred from sequence or structural similarity /// 0043410 // positive regulation of MAPK cascade // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045165 // cell fate commitment // inferred from sequence or structural similarity /// 0045667 // regulation of osteoblast differentiation // traceable author statement /// 0045787 // positive regulation of cell cycle // inferred from sequence or structural similarity /// 0045839 // negative regulation of mitosis // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0048286 // lung alveolus development // inferred from sequence or structural similarity /// 0048333 // mesodermal cell differentiation // inferred from electronic annotation /// 0048489 // synaptic vesicle transport // inferred from electronic annotation /// 0048557 // embryonic digestive tract morphogenesis // inferred from sequence or structural similarity /// 0048562 // embryonic organ morphogenesis // inferred from sequence or structural similarity /// 0048565 // digestive tract development // inferred from sequence or structural similarity /// 0048568 // embryonic organ development // inferred from sequence or structural similarity /// 0048608 // reproductive structure development // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from mutant phenotype /// 0048705 // skeletal system morphogenesis // traceable author statement /// 0048730 // epidermis morphogenesis // inferred from sequence or structural similarity /// 0048755 // branching morphogenesis of a nerve // inferred from sequence or structural similarity /// 0048762 // mesenchymal cell differentiation // inferred from sequence or structural similarity /// 0050673 // epithelial cell proliferation // inferred from electronic annotation /// 0050678 // regulation of epithelial cell proliferation // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from sequence or structural similarity /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation /// 0051150 // regulation of smooth muscle cell differentiation // inferred from sequence or structural similarity /// 0051781 // positive regulation of cell division // inferred from sequence or structural similarity /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060174 // limb bud formation // inferred from sequence or structural similarity /// 0060348 // bone development // inferred from sequence or structural similarity /// 0060349 // bone morphogenesis // inferred from sequence or structural similarity /// 0060365 // coronal suture morphogenesis // inferred from electronic annotation /// 0060442 // branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060445 // branching involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060449 // bud elongation involved in lung branching // inferred from sequence or structural similarity /// 0060463 // lung lobe morphogenesis // inferred from sequence or structural similarity /// 0060484 // lung-associated mesenchyme development // inferred from sequence or structural similarity /// 0060501 // positive regulation of epithelial cell proliferation involved in lung morphogenesis // inferred from sequence or structural similarity /// 0060512 // prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060523 // prostate epithelial cord elongation // inferred from sequence or structural similarity /// 0060527 // prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis // inferred from sequence or structural similarity /// 0060529 // squamous basal epithelial stem cell differentiation involved in prostate gland acinus development // inferred from sequence or structural similarity /// 0060595 // fibroblast growth factor receptor signaling pathway involved in mammary gland specification // inferred from sequence or structural similarity /// 0060601 // lateral sprouting from an epithelium // inferred from sequence or structural similarity /// 0060615 // mammary gland bud formation // inferred from sequence or structural similarity /// 0060664 // epithelial cell proliferation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060667 // branch elongation involved in salivary gland morphogenesis // inferred from sequence or structural similarity /// 0060670 // branching involved in labyrinthine layer morphogenesis // inferred from sequence or structural similarity /// 0060687 // regulation of branching involved in prostate gland morphogenesis // inferred from sequence or structural similarity /// 0060688 // regulation of morphogenesis of a branching structure // inferred from sequence or structural similarity /// 0060915 // mesenchymal cell differentiation involved in lung development // inferred from sequence or structural similarity /// 0060916 // mesenchymal cell proliferation involved in lung development // inferred from sequence or structural similarity /// 0061031 // endodermal digestive tract morphogenesis // inferred from electronic annotation /// 0070307 // lens fiber cell development // inferred from electronic annotation /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred from sequence or structural similarity","0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0060076 // excitatory synapse // inferred from sequence or structural similarity","0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // non-traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from direct assay /// 0005007 // fibroblast growth factor-activated receptor activity // inferred from genetic interaction /// 0005007 // fibroblast growth factor-activated receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from direct assay /// 0017134 // fibroblast growth factor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction","---","IPR000719 // Protein kinase domain // 7.1E-52 /// IPR000719 // Protein kinase domain // 2.8E-52 /// IPR000719 // Protein kinase domain // 5.2E-52 /// IPR000719 // Protein kinase domain // 6.2E-52 /// IPR000719 // Protein kinase domain // 5.2E-52 /// IPR000719 // Protein kinase domain // 5.2E-52 /// IPR001245 // Serine-threonine/tyrosine-protein kinase catalytic domain // 3.4E-107 /// IPR001245 // Serine-threonine/tyrosine-protein kinase catalytic domain // 1.3E-107 /// IPR001245 // Serine-threonine/tyrosine-protein kinase catalytic domain // 2.5E-107 /// IPR001245 // Serine-threonine/tyrosine-protein kinase catalytic domain // 3.0E-107 /// IPR001245 // Serine-threonine/tyrosine-protein kinase catalytic domain // 2.5E-107 /// IPR001245 // Serine-threonine/tyrosine-protein kinase catalytic domain // 2.5E-107 /// IPR013098 // Immunoglobulin I-set // 2.6E-18 /// IPR013098 // Immunoglobulin I-set // 7.6E-15 /// IPR013098 // Immunoglobulin I-set // 3.8E-15 /// IPR013098 // Immunoglobulin I-set // 2.1E-18 /// IPR013098 // Immunoglobulin I-set // 6.1E-15 /// IPR013098 // Immunoglobulin I-set // 3.1E-19 /// IPR013098 // Immunoglobulin I-set // 4.7E-15 /// IPR013098 // Immunoglobulin I-set // 2.1E-18 /// IPR013098 // Immunoglobulin I-set // 6.1E-15 /// IPR013098 // Immunoglobulin I-set // 2.2E-18 /// IPR013151 // Immunoglobulin // 3.3E-12 /// IPR013151 // Immunoglobulin // 3.8E-8 /// IPR013151 // Immunoglobulin // 2.0E-8 /// IPR013151 // Immunoglobulin // 2.7E-12 /// IPR013151 // Immunoglobulin // 3.1E-8 /// IPR013151 // Immunoglobulin // 3.2E-12 /// IPR013151 // Immunoglobulin // 4.6E-13 /// IPR013151 // Immunoglobulin // 2.7E-12 /// IPR013151 // Immunoglobulin // 3.1E-8 /// IPR013151 // Immunoglobulin // 2.7E-12"
"208399_s_at",-2.779407526,-1.843683987,-3.585733671,"DOWN","NM_000114","chr20:57875560-57901046 (+) // 99.73 // q13.32","endothelin 3","EDN3","ENSG00000124205 /// OTTHUMG00000032867","1908","131242 /// 209880 /// 613265 /// 613712","NP_000105 /// NP_996915 /// NP_996916 /// NP_996917 /// XP_005260369 /// XP_005260370 /// XP_005260371 /// XP_006723797","NM_000114 /// NM_207032 /// NM_207033 /// NM_207034 /// XM_005260312 /// XM_005260313 /// XM_005260314 /// XM_006723734","0001755 // neural crest cell migration // inferred from electronic annotation /// 0002690 // positive regulation of leukocyte chemotaxis // inferred from direct assay /// 0003100 // regulation of systemic arterial blood pressure by endothelin // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor signaling pathway // inferred from direct assay /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010460 // positive regulation of heart rate // inferred from direct assay /// 0014824 // artery smooth muscle contraction // inferred from direct assay /// 0014826 // vein smooth muscle contraction // inferred from direct assay /// 0019229 // regulation of vasoconstriction // inferred from electronic annotation /// 0030072 // peptide hormone secretion // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030593 // neutrophil chemotaxis // inferred from direct assay /// 0042310 // vasoconstriction // inferred from direct assay /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay /// 0045840 // positive regulation of mitosis // inferred from direct assay /// 0046887 // positive regulation of hormone secretion // inferred from direct assay /// 0048016 // inositol phosphate-mediated signaling // inferred from direct assay /// 0048070 // regulation of developmental pigmentation // inferred from electronic annotation /// 0050880 // regulation of blood vessel size // inferred from electronic annotation","0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay","0005102 // receptor binding // traceable author statement /// 0005179 // hormone activity // inferred from direct assay","---","IPR001928 // Endothelin-like toxin // 7.9E-22 /// IPR001928 // Endothelin-like toxin // 7.0E-22 /// IPR001928 // Endothelin-like toxin // 7.2E-22"
"208454_s_at",-1.350841068,-1.360033976,-1.129276075,"DOWN","NM_016134","chr8:97797089-98155411 (+) // 98.64 // q22.1","carboxypeptidase Q","CPQ","ENSG00000104324 /// OTTHUMG00000164690","10404","---","NP_057218 /// XP_005250812 /// XP_006716561","NM_016134 /// XM_005250755 /// XM_006716498 /// XR_428374","0006508 // proteolysis // inferred from direct assay /// 0006590 // thyroid hormone generation // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0042246 // tissue regeneration // inferred from sequence or structural similarity /// 0043171 // peptide catabolic process // inferred from direct assay","0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070573 // metallodipeptidase activity // inferred from direct assay","---","IPR002933 // Peptidase M20 // 6.9E-11 /// IPR007484 // Peptidase M28 // 3.4E-22"
"208540_x_at",1.067139947,1.035259977,1.089739023,"UP","NM_021039","chr12:64045406-64045715 (+) // 95.79 // q14.2 /// chr7:102902446-102902755 (+) // 100.0 // q22.1 /// chr7:35208835-35209144 (+) // 97.73 // p14.2","S100 calcium binding protein A11 pseudogene 1 /// ---","S100A11P1 /// S100A11P1","ENSG00000237632 /// OTTHUMG00000157211","---","---","---","---","---","---","---","---","---"
"208712_at",1.161684446,1.297874583,1.242736275,"UP","M73554","chr11:69455940-69469238 (+) // 97.77 // q13.3","cyclin D1","CCND1","ENSG00000110092 /// OTTHUMG00000167877","595","168461 /// 193300 /// 254500","NP_444284 /// XP_006718716","NM_053056 /// XM_006718653","0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0000082 // G1/S transition of mitotic cell cycle // inferred from direct assay /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000278 // mitotic cell cycle // traceable author statement /// 0000320 // re-entry into mitotic cell cycle // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007219 // Notch signaling pathway // traceable author statement /// 0007595 // lactation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010039 // response to iron ion // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from electronic annotation /// 0010243 // response to organonitrogen compound // inferred from electronic annotation /// 0010971 // positive regulation of G2/M transition of mitotic cell cycle // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030857 // negative regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0031571 // mitotic G1 DNA damage checkpoint // inferred from direct assay /// 0032026 // response to magnesium ion // inferred from electronic annotation /// 0033197 // response to vitamin E // inferred from electronic annotation /// 0033327 // Leydig cell differentiation // inferred from electronic annotation /// 0033598 // mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0033601 // positive regulation of mammary gland epithelial cell proliferation // inferred from electronic annotation /// 0042493 // response to drug // inferred from expression pattern /// 0043627 // response to estrogen // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045737 // positive regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045859 // regulation of protein kinase activity // inferred from electronic annotation /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060749 // mammary gland alveolus development // inferred from electronic annotation /// 0070141 // response to UV-A // inferred from direct assay /// 0071157 // negative regulation of cell cycle arrest // inferred from direct assay /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation","0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from direct assay /// 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from direct assay","0003714 // transcription corepressor activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016538 // cyclin-dependent protein serine/threonine kinase regulator activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0070064 // proline-rich region binding // inferred from direct assay","G1_to_S_cell_cycle_Reactome // GenMAPP /// Wnt_signaling // GenMAPP","IPR004367 // Cyclin, C-terminal domain // 8.2E-26 /// IPR006671 // Cyclin, N-terminal // 5.6E-42"
"208892_s_at",1.817339181,1.36092194,1.005585471,"UP","BC003143","chr12:89741838-89746164 (-) // 99.0 // q21.33","dual specificity phosphatase 6","DUSP6","ENSG00000139318 /// OTTHUMG00000169912","1848","602748 /// 615269","NP_001937 /// NP_073143","NM_001946 /// NM_022652","0000188 // inactivation of MAPK activity // inferred from direct assay /// 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // not recorded /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0040036 // regulation of fibroblast growth factor receptor signaling pathway // not recorded /// 0042493 // response to drug // inferred from electronic annotation /// 0042663 // regulation of endodermal cell fate specification // not recorded /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051409 // response to nitrosative stress // inferred from expression pattern /// 0060420 // regulation of heart growth // not recorded /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070848 // response to growth factor // inferred from electronic annotation","0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // ---","0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from direct assay","---","IPR000340 // Dual specificity phosphatase, catalytic domain // 9.8E-47 /// IPR000340 // Dual specificity phosphatase, catalytic domain // 7.7E-29 /// IPR001763 // Rhodanese-like domain // 9.8E-18 /// IPR001763 // Rhodanese-like domain // 7.1E-14"
"208893_s_at",1.755155122,1.262221961,1.309638334,"UP","BC005047","chr12:89742405-89746240 (-) // 99.14 // q21.33","dual specificity phosphatase 6","DUSP6","ENSG00000139318 /// OTTHUMG00000169912","1848","602748 /// 615269","NP_001937 /// NP_073143","NM_001946 /// NM_022652","0000188 // inactivation of MAPK activity // inferred from direct assay /// 0001933 // negative regulation of protein phosphorylation // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // not recorded /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0040036 // regulation of fibroblast growth factor receptor signaling pathway // not recorded /// 0042493 // response to drug // inferred from electronic annotation /// 0042663 // regulation of endodermal cell fate specification // not recorded /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051409 // response to nitrosative stress // inferred from expression pattern /// 0060420 // regulation of heart growth // not recorded /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070848 // response to growth factor // inferred from electronic annotation","0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // ---","0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from direct assay","---","IPR000340 // Dual specificity phosphatase, catalytic domain // 9.8E-47 /// IPR000340 // Dual specificity phosphatase, catalytic domain // 7.7E-29 /// IPR001763 // Rhodanese-like domain // 9.8E-18 /// IPR001763 // Rhodanese-like domain // 7.1E-14"
"208894_at",1.207822094,1.006275347,1.078222355,"UP","M60334","chr6:32407700-32411702 (+) // 98.17 // p21.32","major histocompatibility complex, class II, DR alpha","HLA-DRA","ENSG00000227993 /// ENSG00000228987 /// OTTHUMG00000031567 /// OTTHUMG00000149060","3122","142860","NP_061984","NM_019111","0002376 // immune system process // inferred from electronic annotation /// 0002503 // peptide antigen assembly with MHC class II protein complex // inferred from direct assay /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from direct assay /// 0002506 // polysaccharide assembly with MHC class II protein complex // inferred from direct assay /// 0006955 // immune response // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050890 // cognition // inferred from mutant phenotype /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement","0000139 // Golgi membrane // traceable author statement /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0031902 // late endosome membrane // inferred from direct assay /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042613 // MHC class II protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement","0005515 // protein binding // inferred from electronic annotation /// 0023026 // MHC class II protein complex binding // inferred from direct assay /// 0032395 // MHC class II receptor activity // non-traceable author statement /// 0042605 // peptide antigen binding // inferred from direct assay","---","IPR001003 // MHC class II, alpha chain, N-terminal // 5.2E-36 /// IPR003597 // Immunoglobulin C1-set // 5.4E-29"
"208949_s_at",1.65188202,1.782066362,2.057792576,"UP","BC001120","chr14:55604086-55612006 (+) // 94.4 // q22.3","lectin, galactoside-binding, soluble, 3","LGALS3","ENSG00000131981 /// OTTHUMG00000171030","3958","153619","NP_001170859 /// NP_002297","NM_001177388 /// NM_002306 /// NR_003225","0001501 // skeletal system development // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002548 // monocyte chemotaxis // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030593 // neutrophil chemotaxis // inferred from direct assay /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0042129 // regulation of T cell proliferation // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045806 // negative regulation of endocytosis // inferred from direct assay /// 0048245 // eosinophil chemotaxis // inferred from direct assay /// 0048246 // macrophage chemotaxis // inferred from direct assay /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from sequence or structural similarity /// 0050918 // positive chemotaxis // inferred from direct assay /// 0070232 // regulation of T cell apoptotic process // inferred from direct assay /// 0071674 // mononuclear cell migration // inferred from direct assay /// 0071677 // positive regulation of mononuclear cell migration // inferred from direct assay /// 0090280 // positive regulation of calcium ion import // inferred from direct assay /// 1902041 // regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from mutant phenotype /// 2000521 // negative regulation of immunological synapse formation // inferred from sequence or structural similarity /// 2001189 // negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell // inferred from sequence or structural similarity /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from direct assay","0001772 // immunological synapse // inferred from direct assay /// 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005515 // protein binding // inferred from physical interaction /// 0019863 // IgE binding // inferred from direct assay /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0042056 // chemoattractant activity // inferred from direct assay /// 0043236 // laminin binding // inferred from direct assay /// 0044822 // poly(A) RNA binding // inferred from direct assay","---","IPR001079 // Galectin, carbohydrate recognition domain // 4.8E-42"
"209116_x_at",-1.559317816,-1.630185276,-1.700281483,"DOWN","M25079","chr11:5247806-5248231 (-) // 62.61 // p15.4","hemoglobin, beta","HBB","ENSG00000244734 /// OTTHUMG00000066678","3043","140700 /// 141749 /// 141900 /// 603902 /// 603903 /// 604131 /// 611162 /// 613985","NP_000509","NM_000518","0006810 // transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0015671 // oxygen transport // non-traceable author statement /// 0015671 // oxygen transport // traceable author statement /// 0015701 // bicarbonate transport // traceable author statement /// 0030185 // nitric oxide transport // non-traceable author statement /// 0042542 // response to hydrogen peroxide // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // non-traceable author statement /// 0050880 // regulation of blood vessel size // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0070293 // renal absorption // inferred from mutant phenotype","0005576 // extracellular region // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005833 // hemoglobin complex // inferred from direct assay /// 0005833 // hemoglobin complex // non-traceable author statement /// 0005833 // hemoglobin complex // traceable author statement /// 0031838 // haptoglobin-hemoglobin complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay","0004601 // peroxidase activity // inferred from direct assay /// 0005344 // oxygen transporter activity // non-traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019825 // oxygen binding // inferred from direct assay /// 0020037 // heme binding // inferred from electronic annotation /// 0030492 // hemoglobin binding // inferred from direct assay /// 0031720 // haptoglobin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000971 // Globin // 3.5E-33"
"209173_at",2.390125036,2.607180683,2.047065347,"UP","AF088867","chr7:16832265-16844697 (-) // 98.33 // p21.1","anterior gradient 2","AGR2","ENSG00000106541 /// OTTHUMG00000023446","10551","606358","NP_006399 /// XP_005249638","NM_006408 /// XM_005249581","0060480 // lung goblet cell differentiation // inferred from electronic annotation /// 0070254 // mucus secretion // inferred from sequence or structural similarity","0005576 // extracellular region // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity","0002162 // dystroglycan binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction","---","---"
"209189_at",-1.160453648,-1.000703084,-1.837391565,"DOWN","BC004490","chr14:75745558-75748651 (+) // 98.3 // q24.3","FBJ murine osteosarcoma viral oncogene homolog","FOS","ENSG00000170345 /// OTTHUMG00000171774","2353","164810","NP_005243","NM_005252","0001661 // conditioned taste aversion // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006306 // DNA methylation // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007399 // nervous system development // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009629 // response to gravity // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030431 // sleep // inferred from electronic annotation /// 0031668 // cellular response to extracellular stimulus // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0034614 // cellular response to reactive oxygen species // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045672 // positive regulation of osteoclast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0071277 // cellular response to calcium ion // inferred from electronic annotation","0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation","0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from direct assay /// 0070412 // R-SMAD binding // inferred from physical interaction","Smooth_muscle_contraction // GenMAPP /// TGF_Beta_Signaling_Pathway // GenMAPP","IPR004827 // Basic-leucine zipper domain // 5.0E-13 /// IPR004827 // Basic-leucine zipper domain // 1.1E-11"
"209227_at",2.273839235,1.338993962,1.131941938,"UP","AU158251","chr8:15397731-15622854 (+) // 89.9 // p22","tumor suppressor candidate 3","TUSC3","ENSG00000104723 /// OTTHUMG00000094803","7991","601385 /// 611093","NP_006756 /// NP_839952 /// XP_005273703 /// XP_005273704 /// XP_005273705","NM_006765 /// NM_178234 /// XM_005273646 /// XM_005273647 /// XM_005273648","0006487 // protein N-linked glycosylation // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015693 // magnesium ion transport // inferred from genetic interaction /// 0015693 // magnesium ion transport // inferred from mutant phenotype /// 0018279 // protein N-linked glycosylation via asparagine // inferred from sequence or structural similarity /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0050890 // cognition // inferred from mutant phenotype","0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0008250 // oligosaccharyltransferase complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0004579 // dolichyl-diphosphooligosaccharide-protein glycotransferase activity // inferred from sequence or structural similarity /// 0015095 // magnesium ion transmembrane transporter activity // inferred from mutant phenotype","---","IPR013766 // Thioredoxin domain // 9.3E-9 /// IPR021149 // Oligosaccharyl transferase complex, subunit OST3/OST6 // 4.3E-57"
"209242_at",-2.130356717,-1.445965347,-1.203095948,"DOWN","AL042588","chr19:57321447-57352064 (-) // 93.21 // q13.43","paternally expressed 3","PEG3","ENSG00000198300 /// OTTHUMG00000171954","5178","601483","NP_001139656 /// NP_001139657 /// NP_001139658 /// NP_001139659 /// NP_006201","NM_001146184 /// NM_001146185 /// NM_001146186 /// NM_001146187 /// NM_006210","0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // not recorded /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0006915 // apoptotic process // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0071514 // genetic imprinting // inferred from electronic annotation","0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation","0000981 // sequence-specific DNA binding RNA polymerase II transcription factor activity // not recorded /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // --- /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR003309 // Transcription regulator SCAN // 7.0E-37 /// IPR007087 // Zinc finger, C2H2 // 6.4E-8"
"209270_at",2.883073035,2.454663814,2.869708696,"UP","L25541","chr1:209788321-209825674 (-) // 99.19 // q32.2","laminin, beta 3","LAMB3","---","3914","150310 /// 226650 /// 226700","NP_000219 /// NP_001017402 /// NP_001121113 /// XP_005273181","NM_000228 /// NM_001017402 /// NM_001127641 /// XM_005273124","0007155 // cell adhesion // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0031581 // hemidesmosome assembly // traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0050873 // brown fat cell differentiation // inferred from electronic annotation","0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005610 // laminin-5 complex // inferred from electronic annotation","0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0032403 // protein complex binding // inferred from electronic annotation","---","---"
"209288_s_at",1.354091162,1.432157316,1.366057451,"UP","AL136842","chr2:37871982-37899299 (-) // 94.76 // p22.2","CDC42 effector protein (Rho GTPase binding) 3","CDC42EP3","ENSG00000163171 /// OTTHUMG00000100971","10602","606133","NP_001257365 /// NP_001257366 /// NP_001257367 /// NP_006440","NM_001270436 /// NM_001270437 /// NM_001270438 /// NM_006449","0007165 // signal transduction // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation","0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation","0005515 // protein binding // inferred from electronic annotation /// 0005519 // cytoskeletal regulatory protein binding // traceable author statement","---","IPR000095 // CRIB domain // 7.4E-13"
"209292_at",-2.210445532,-1.641742692,-1.125350382,"DOWN","AL022726","chr6:19837617-19842428 (+) // 96.66 // p22.3","inhibitor of DNA binding 4, dominant negative helix-loop-helix protein","ID4","---","3400","600581","NP_001537 /// XP_005249133","NM_001546 /// XM_005249076","0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007405 // neuroblast proliferation // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021895 // cerebral cortex neuron differentiation // inferred from electronic annotation /// 0022010 // central nervous system myelination // inferred from electronic annotation /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from electronic annotation","0005634 // nucleus // inferred by curator /// 0005737 // cytoplasm // inferred from electronic annotation","0001085 // RNA polymerase II transcription factor binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation","---","---"
"209293_x_at",-1.754070532,-1.721220602,-1.050501781,"DOWN","U16153","chr6:19837671-19839661 (+) // 95.67 // p22.3","inhibitor of DNA binding 4, dominant negative helix-loop-helix protein","ID4","ENSG00000172201 /// OTTHUMG00000014333","3400","600581","NP_001537 /// XP_005249133","NM_001546 /// XM_005249076","0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007405 // neuroblast proliferation // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0021766 // hippocampus development // inferred from electronic annotation /// 0021895 // cerebral cortex neuron differentiation // inferred from electronic annotation /// 0022010 // central nervous system myelination // inferred from electronic annotation /// 0034613 // cellular protein localization // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048712 // negative regulation of astrocyte differentiation // inferred from electronic annotation /// 0048715 // negative regulation of oligodendrocyte differentiation // inferred from electronic annotation","0005634 // nucleus // inferred by curator /// 0005737 // cytoplasm // inferred from electronic annotation","0001085 // RNA polymerase II transcription factor binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046983 // protein dimerization activity // inferred from electronic annotation","---","IPR011598 // Myc-type, basic helix-loop-helix (bHLH) domain // 5.9E-18"
"209325_s_at",-1.375354673,-1.651439561,-1.301175865,"DOWN","U94829","chr1:182567903-182573397 (-) // 96.86 // q25.3","regulator of G-protein signaling 16","RGS16","ENSG00000143333 /// OTTHUMG00000035212","6004","602514","NP_002919","NM_002928","0007601 // visual perception // traceable author statement /// 0008277 // regulation of G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded /// 0043547 // positive regulation of GTPase activity // traceable author statement","0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // not recorded","0005096 // GTPase activator activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // traceable author statement","Calcium_regulation_in_cardiac_cells // GenMAPP /// Smooth_muscle_contraction // GenMAPP","IPR000342 // Regulator of G protein signalling domain // 1.8E-39"
"209335_at",-1.593497736,-1.28826742,-1.153251883,"DOWN","AI281593","chr12:91539034-91573308 (-) // 91.66 // q21.33","decorin","DCN","ENSG00000011465 /// OTTHUMG00000169998","1634","125255 /// 610048","NP_001911 /// NP_598010 /// NP_598011 /// NP_598012 /// NP_598013 /// NP_598014 /// XP_005268750 /// XP_006719333","NM_001920 /// NM_133503 /// NM_133504 /// NM_133505 /// NM_133506 /// NM_133507 /// XM_005268693 /// XM_006719270","0001822 // kidney development // inferred from electronic annotation /// 0001890 // placenta development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007519 // skeletal muscle tissue development // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0019800 // peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0042060 // wound healing // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement","0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005589 // collagen type VI trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043202 // lysosomal lumen // traceable author statement","0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from electronic annotation /// 0005539 // glycosaminoglycan binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation","---","IPR000372 // Leucine-rich repeat-containing N-terminal // 1.3E-13 /// IPR000372 // Leucine-rich repeat-containing N-terminal // 1.1E-9 /// IPR001611 // Leucine-rich repeat // 5.5E-5 /// IPR001611 // Leucine-rich repeat // 2.6E-5 /// IPR001611 // Leucine-rich repeat // 5.7E-5 /// IPR001611 // Leucine-rich repeat // 2.9E-5"
"209357_at",-1.772708347,-1.280365225,-1.6462174,"DOWN","AF109161","chr6:139693394-139695757 (-) // 96.35 // q24.1","Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2","CITED2","ENSG00000164442 /// OTTHUMG00000015691","10370","602937 /// 614431 /// 614433","NP_001161860 /// NP_001161861 /// NP_006070","NM_001168388 /// NM_001168389 /// NM_006079","0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from direct assay /// 0001666 // response to hypoxia // inferred from mutant phenotype /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001829 // trophectodermal cell differentiation // inferred from electronic annotation /// 0001841 // neural tube formation // inferred from electronic annotation /// 0001843 // neural tube closure // inferred from electronic annotation /// 0001889 // liver development // inferred from sequence or structural similarity /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0001944 // vasculature development // inferred from electronic annotation /// 0001947 // heart looping // inferred from electronic annotation /// 0002089 // lens morphogenesis in camera-type eye // inferred from electronic annotation /// 0002244 // hematopoietic progenitor cell differentiation // inferred from electronic annotation /// 0002521 // leukocyte differentiation // inferred from electronic annotation /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003156 // regulation of organ formation // inferred from sequence or structural similarity /// 0003197 // endocardial cushion development // inferred from electronic annotation /// 0003281 // ventricular septum development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007368 // determination of left/right symmetry // inferred from sequence or structural similarity /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007422 // peripheral nervous system development // inferred from electronic annotation /// 0007507 // heart development // inferred from mutant phenotype /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007530 // sex determination // inferred from sequence or structural similarity /// 0007569 // cell aging // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0008584 // male gonad development // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from direct assay /// 0010629 // negative regulation of gene expression // inferred from direct assay /// 0021602 // cranial nerve morphogenesis // inferred from electronic annotation /// 0022409 // positive regulation of cell-cell adhesion // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030325 // adrenal gland development // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from mutant phenotype /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from sequence or structural similarity /// 0030851 // granulocyte differentiation // inferred from electronic annotation /// 0034405 // response to fluid shear stress // inferred from mutant phenotype /// 0035360 // positive regulation of peroxisome proliferator activated receptor signaling pathway // inferred from direct assay /// 0035802 // adrenal cortex formation // inferred from sequence or structural similarity /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from sequence or structural similarity /// 0043627 // response to estrogen // inferred from direct assay /// 0045787 // positive regulation of cell cycle // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046697 // decidualization // inferred from electronic annotation /// 0048536 // spleen development // inferred from sequence or structural similarity /// 0048538 // thymus development // inferred from electronic annotation /// 0048596 // embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0048821 // erythrocyte development // inferred from electronic annotation /// 0060136 // embryonic process involved in female pregnancy // inferred from electronic annotation /// 0060349 // bone morphogenesis // inferred from electronic annotation /// 0060411 // cardiac septum morphogenesis // inferred from electronic annotation /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0060971 // embryonic heart tube left/right pattern formation // inferred from sequence or structural similarity /// 0061156 // pulmonary artery morphogenesis // inferred from electronic annotation /// 0061308 // cardiac neural crest cell development involved in heart development // inferred from electronic annotation /// 0061371 // determination of heart left/right asymmetry // inferred from electronic annotation /// 0061428 // negative regulation of transcription from RNA polymerase II promoter in response to hypoxia // inferred from direct assay /// 0070986 // left/right axis specification // inferred from sequence or structural similarity /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 1900164 // nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry // inferred from sequence or structural similarity /// 2000020 // positive regulation of male gonad development // inferred from sequence or structural similarity /// 2001141 // regulation of RNA biosynthetic process // inferred from direct assay","0000790 // nuclear chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from mutant phenotype","0001102 // RNA polymerase II activating transcription factor binding // inferred from electronic annotation /// 0001105 // RNA polymerase II transcription coactivator activity // inferred from electronic annotation /// 0001106 // RNA polymerase II transcription corepressor activity // inferred from direct assay /// 0003682 // chromatin binding // inferred from sequence or structural similarity /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0003714 // transcription corepressor activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0035035 // histone acetyltransferase binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0050693 // LBD domain binding // inferred from physical interaction","---","IPR007576 // CITED // 2.2E-36 /// IPR007576 // CITED // 1.2E-49"
"209360_s_at",2.258059087,1.835566438,1.63184771,"UP","D43968","chr21:36160104-36260987 (-) // 94.73 // q22.12","uncharacterized LOC100506403 /// uncharacterized LOC101928269 /// runt-related transcription factor 1","LOC100506403 /// LOC101928269 /// RUNX1","ENSG00000159216 /// OTTHUMG00000086299","861 /// 100506403 /// 101928269","151385 /// 601399","NP_001001890 /// NP_001116079 /// NP_001745 /// XP_005261125 /// XP_005261126","NM_001001890 /// NM_001122607 /// NM_001754 /// NR_073512 /// NR_110418 /// XM_005261068 /// XM_005261069 /// XR_244307 /// XR_248986 /// XR_254030","0001501 // skeletal system development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0002318 // myeloid progenitor cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from direct assay /// 0030097 // hemopoiesis // traceable author statement /// 0030099 // myeloid cell differentiation // inferred from direct assay /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0030853 // negative regulation of granulocyte differentiation // inferred from mutant phenotype /// 0030854 // positive regulation of granulocyte differentiation // inferred from mutant phenotype /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048266 // behavioral response to pain // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0048935 // peripheral nervous system neuron development // traceable author statement /// 0060216 // definitive hemopoiesis // inferred from electronic annotation /// 0071336 // regulation of hair follicle cell proliferation // inferred from electronic annotation /// 0071425 // hematopoietic stem cell proliferation // traceable author statement /// 2000872 // positive regulation of progesterone secretion // inferred from electronic annotation","0005604 // basement membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay","0000975 // regulatory region DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0070491 // repressing transcription factor binding // inferred from electronic annotation","---","IPR013524 // Runt domain // 6.5E-79 /// IPR013524 // Runt domain // 7.2E-79 /// IPR013711 // Runx, C-terminal  domain // 4.3E-46 /// IPR013711 // Runx, C-terminal  domain // 4.7E-46"
"209395_at",4.306400294,4.629372545,3.609101936,"UP","M80927","chr1:203148056-203155822 (-) // 99.43 // q32.1","chitinase 3-like 1 (cartilage glycoprotein-39)","CHI3L1","ENSG00000133048 /// OTTHUMG00000042122","1116","181500 /// 601525 /// 611960","NP_001267","NM_001276","0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006032 // chitin catabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from expression pattern /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from sequence or structural similarity /// 0009612 // response to mechanical stimulus // inferred from expression pattern /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from mutant phenotype /// 0034612 // response to tumor necrosis factor // inferred from expression pattern /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0051216 // cartilage development // non-traceable author statement /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070555 // response to interleukin-1 // inferred from expression pattern /// 0070741 // response to interleukin-6 // inferred from expression pattern /// 0071356 // cellular response to tumor necrosis factor // inferred from sequence or structural similarity /// 0072606 // interleukin-8 secretion // inferred from sequence or structural similarity","0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004568 // chitinase activity // inferred from direct assay /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0008061 // chitin binding // inferred from direct assay","---","IPR001223 // Glycoside hydrolase, family 18, catalytic domain // 3.0E-112 /// IPR001223 // Glycoside hydrolase, family 18, catalytic domain // 1.0E-21 /// IPR001223 // Glycoside hydrolase, family 18, catalytic domain // 3.8E-18"
"209396_s_at",3.800722227,4.254889609,3.227019151,"UP","M80927","chr1:203148056-203155822 (-) // 99.43 // q32.1","chitinase 3-like 1 (cartilage glycoprotein-39)","CHI3L1","ENSG00000133048 /// OTTHUMG00000042122","1116","181500 /// 601525 /// 611960","NP_001267","NM_001276","0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006032 // chitin catabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from expression pattern /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from sequence or structural similarity /// 0009612 // response to mechanical stimulus // inferred from expression pattern /// 0010800 // positive regulation of peptidyl-threonine phosphorylation // inferred from sequence or structural similarity /// 0030324 // lung development // inferred from mutant phenotype /// 0034612 // response to tumor necrosis factor // inferred from expression pattern /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0051216 // cartilage development // non-traceable author statement /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 0070555 // response to interleukin-1 // inferred from expression pattern /// 0070741 // response to interleukin-6 // inferred from expression pattern /// 0071356 // cellular response to tumor necrosis factor // inferred from sequence or structural similarity /// 0072606 // interleukin-8 secretion // inferred from sequence or structural similarity","0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0003824 // catalytic activity // inferred from electronic annotation /// 0004553 // hydrolase activity, hydrolyzing O-glycosyl compounds // inferred from electronic annotation /// 0004568 // chitinase activity // inferred from direct assay /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0008061 // chitin binding // inferred from direct assay","---","IPR001223 // Glycoside hydrolase, family 18, catalytic domain // 3.0E-112 /// IPR001223 // Glycoside hydrolase, family 18, catalytic domain // 1.0E-21 /// IPR001223 // Glycoside hydrolase, family 18, catalytic domain // 3.8E-18"
"209447_at",-1.125958038,-1.490293571,-1.970704305,"DOWN","AF043290","chr6:152442914-152461297 (-) // 97.51 // q25.1","spectrin repeat containing, nuclear envelope 1","SYNE1","ENSG00000131018 /// OTTHUMG00000015841","23345","608441 /// 610743 /// 612998","NP_149062 /// NP_892006 /// XP_006715470 /// XP_006715471 /// XP_006715472 /// XP_006715473 /// XP_006715474 /// XP_006715475 /// XP_006715476 /// XP_006715477 /// XP_006715478 /// XP_006715479 /// XP_006715480 /// XP_006715481 /// XP_006715482 /// XP_006715483 /// XP_006715484 /// XP_006715485 /// XP_006715486 /// XP_006715487 /// XP_006715488","NM_001099267 /// NM_001134379 /// NM_015293 /// NM_033071 /// NM_133650 /// NM_182961 /// XM_006715407 /// XM_006715408 /// XM_006715409 /// XM_006715410 /// XM_006715411 /// XM_006715412 /// XM_006715413 /// XM_006715414 /// XM_006715415 /// XM_006715416 /// XM_006715417 /// XM_006715418 /// XM_006715419 /// XM_006715420 /// XM_006715421 /// XM_006715422 /// XM_006715423 /// XM_006715424 /// XM_006715425","0006810 // transport // inferred from electronic annotation /// 0006997 // nucleus organization // non-traceable author statement /// 0007030 // Golgi organization // inferred from direct assay /// 0008219 // cell death // inferred from electronic annotation /// 0042692 // muscle cell differentiation // inferred from direct assay /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0090286 // cytoskeletal anchoring at nuclear membrane // inferred from direct assay /// 0090292 // nuclear matrix anchoring at nuclear membrane // inferred from direct assay","0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005640 // nuclear outer membrane // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0030017 // sarcomere // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0034993 // SUN-KASH complex // inferred from direct assay /// 0045211 // postsynaptic membrane // inferred from direct assay","0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005521 // lamin binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from sequence or structural similarity","---","IPR001715 // Calponin homology domain // 1.2E-17 /// IPR001715 // Calponin homology domain // 6.8E-23 /// IPR001715 // Calponin homology domain // 4.2E-15 /// IPR001715 // Calponin homology domain // 6.8E-23 /// IPR001715 // Calponin homology domain // 1.1E-17 /// IPR001715 // Calponin homology domain // 6.5E-23 /// IPR002017 // Spectrin repeat // 1.1E-10 /// IPR002017 // Spectrin repeat // 4.0E-11 /// IPR002017 // Spectrin repeat // 3.5E-9 /// IPR002017 // Spectrin repeat // 1.7E-10 /// IPR002017 // Spectrin repeat // 4.8E-9 /// IPR002017 // Spectrin repeat // 9.1E-12 /// IPR002017 // Spectrin repeat // 1.0E-11 /// IPR002017 // Spectrin repeat // 1.3E-8 /// IPR002017 // Spectrin repeat // 4.7E-10 /// IPR002017 // Spectrin repeat // 2.1E-13 /// IPR002017 // Spectrin repeat // 6.1E-10 /// IPR002017 // Spectrin repeat // 1.7E-9 /// IPR002017 // Spectrin repeat // 1.1E-11 /// IPR002017 // Spectrin repeat // 1.0E-14 /// IPR002017 // Spectrin repeat // 1.6E-12 /// IPR002017 // Spectrin repeat // 1.1E-9 /// IPR002017 // Spectrin repeat // 4.1E-13 /// IPR002017 // Spectrin repeat // 4.9E-10 /// IPR002017 // Spectrin repeat // 1.4E-9 /// IPR002017 // Spectrin repeat // 8.7E-12 /// IPR002017 // Spectrin repeat // 8.2E-15 /// IPR002017 // Spectrin repeat // 1.1E-10 /// IPR002017 // Spectrin repeat // 5.9E-11 /// IPR002017 // Spectrin repeat // 3.5E-9 /// IPR002017 // Spectrin repeat // 1.7E-10 /// IPR002017 // Spectrin repeat // 4.8E-9 /// IPR002017 // Spectrin repeat // 9.0E-12 /// IPR002017 // Spectrin repeat // 1.0E-11 /// IPR002017 // Spectrin repeat // 1.3E-8 /// IPR002017 // Spectrin repeat // 4.6E-10 /// IPR002017 // Spectrin repeat // 2.1E-13 /// IPR002017 // Spectrin repeat // 4.0E-10 /// IPR002017 // Spectrin repeat // 4.6E-13 /// IPR002017 // Spectrin repeat // 1.4E-9 /// IPR002017 // Spectrin repeat // 5.3E-13 /// IPR002017 // Spectrin repeat // 6.3E-10 /// IPR002017 // Spectrin repeat // 1.7E-9 /// IPR002017 // Spectrin repeat // 1.1E-11 /// IPR002017 // Spectrin repeat // 1.1E-14 /// IPR002017 // Spectrin repeat // 6.3E-10 /// IPR002017 // Spectrin repeat // 1.8E-9 /// IPR002017 // Spectrin repeat // 1.1E-14 /// IPR002017 // Spectrin repeat // 1.0E-10 /// IPR002017 // Spectrin repeat // 3.3E-9 /// IPR002017 // Spectrin repeat // 1.6E-10 /// IPR002017 // Spectrin repeat // 4.6E-9 /// IPR002017 // Spectrin repeat // 8.6E-12 /// IPR002017 // Spectrin repeat // 9.9E-12 /// IPR002017 // Spectrin repeat // 1.2E-8 /// IPR002017 // Spectrin repeat // 4.4E-10 /// IPR002017 // Spectrin repeat // 2.0E-13 /// IPR012315 // KASH domain // 5.8E-33 /// IPR012315 // KASH domain // 3.2E-34 /// IPR012315 // KASH domain // 5.7E-33 /// IPR012315 // KASH domain // 3.3E-34 /// IPR012315 // KASH domain // 5.5E-33"
"209457_at",1.553886495,2.237138337,1.87822783,"UP","U16996","chr10:112257834-112271121 (+) // 96.59 // q25.2","dual specificity phosphatase 5","DUSP5","ENSG00000138166 /// OTTHUMG00000019040","1847","603069","NP_004410","NM_004419","0000188 // inactivation of MAPK activity // inferred from electronic annotation /// 0001706 // endoderm formation // not recorded /// 0006470 // protein dephosphorylation // not recorded /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement","0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // ---","0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation","---","IPR000242 // Protein-tyrosine phosphatase, receptor/non-receptor type // 1.9E-9 /// IPR000340 // Dual specificity phosphatase, catalytic domain // 1.8E-50 /// IPR001763 // Rhodanese-like domain // 2.4E-10"
"209458_x_at",-1.388732988,-1.639938584,-1.653199001,"DOWN","AF105974","chr16:226694-227448 (+) // 100.0 // p13.3 /// chr16:222890-223613 (+) // 95.08 // p13.3","hemoglobin, alpha 1 /// hemoglobin, alpha 2","HBA1 /// HBA2","ENSG00000188536 /// ENSG00000206172 /// OTTHUMG00000059924 /// OTTHUMG00000060138","3039 /// 3040","140700 /// 141800 /// 141850 /// 604131 /// 613978","NP_000508 /// NP_000549","NM_000517 /// NM_000558","0006810 // transport // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0015671 // oxygen transport // traceable author statement /// 0015701 // bicarbonate transport // traceable author statement /// 0042542 // response to hydrogen peroxide // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay","0005576 // extracellular region // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005833 // hemoglobin complex // inferred from direct assay /// 0005833 // hemoglobin complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0031838 // haptoglobin-hemoglobin complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay","0004601 // peroxidase activity // inferred from direct assay /// 0005344 // oxygen transporter activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019825 // oxygen binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0031720 // haptoglobin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000971 // Globin // 2.9E-32"
"209469_at",-3.490654381,-2.335919381,-2.065447882,"DOWN","BF939489","chr4:176554088-176733472 (-) // 98.86 // q34.2","glycoprotein M6A","GPM6A","ENSG00000150625 /// OTTHUMG00000160760","2823","601275","NP_001248376 /// NP_001248377 /// NP_005268 /// NP_963885 /// NP_963886 /// XP_006714246","NM_001261447 /// NM_001261448 /// NM_005277 /// NM_201591 /// NM_201592 /// NR_048571 /// XM_006714183","0001764 // neuron migration // inferred from direct assay /// 0003407 // neural retina development // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0048812 // neuron projection morphogenesis // inferred from sequence or structural similarity /// 0048863 // stem cell differentiation // inferred from direct assay /// 0051491 // positive regulation of filopodium assembly // inferred from sequence or structural similarity /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation","0005886 // plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from sequence or structural similarity /// 0030424 // axon // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from electronic annotation /// 0044295 // axonal growth cone // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction","---","IPR001614 // Myelin proteolipid protein PLP // 1.5E-110"
"209470_s_at",-3.638497214,-2.347943047,-3.053306345,"DOWN","D49958","chr4:176554601-176733472 (-) // 98.99 // q34.2","glycoprotein M6A","GPM6A","ENSG00000150625 /// OTTHUMG00000160760","2823","601275","NP_001248376 /// NP_001248377 /// NP_005268 /// NP_963885 /// NP_963886 /// XP_006714246","NM_001261447 /// NM_001261448 /// NM_005277 /// NM_201591 /// NM_201592 /// NR_048571 /// XM_006714183","0001764 // neuron migration // inferred from direct assay /// 0003407 // neural retina development // inferred from sequence or structural similarity /// 0007399 // nervous system development // inferred from electronic annotation /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0048812 // neuron projection morphogenesis // inferred from sequence or structural similarity /// 0048863 // stem cell differentiation // inferred from direct assay /// 0051491 // positive regulation of filopodium assembly // inferred from sequence or structural similarity /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation","0005886 // plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from sequence or structural similarity /// 0030424 // axon // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from electronic annotation /// 0044295 // axonal growth cone // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction","---","IPR001614 // Myelin proteolipid protein PLP // 1.5E-110 /// IPR001614 // Myelin proteolipid protein PLP // 1.3E-110"
"209473_at",2.116994925,1.876949255,1.679012115,"UP","AV717590","chr10:97582992-97628298 (+) // 86.02 // q24.1","ectonucleoside triphosphate diphosphohydrolase 1","ENTPD1","ENSG00000138185 /// OTTHUMG00000018818","953","601752 /// 615683","NP_001091645 /// NP_001157650 /// NP_001157651 /// NP_001157653 /// NP_001157654 /// NP_001157655 /// NP_001767 /// XP_006718139 /// XP_006718140","NM_001098175 /// NM_001164178 /// NM_001164179 /// NM_001164181 /// NM_001164182 /// NM_001164183 /// NM_001776 /// XM_006718076 /// XM_006718077","0006200 // ATP catabolic process // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009181 // purine ribonucleoside diphosphate catabolic process // inferred from electronic annotation /// 0030168 // platelet activation // inferred from electronic annotation","0005605 // basal lamina // inferred from electronic annotation /// 0005886 // plasma membrane // non-traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017110 // nucleoside-diphosphatase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation","---","IPR000407 // Nucleoside phosphatase GDA1/CD39 // 7.7E-162 /// IPR000407 // Nucleoside phosphatase GDA1/CD39 // 8.0E-162 /// IPR000407 // Nucleoside phosphatase GDA1/CD39 // 2.4E-133 /// IPR000407 // Nucleoside phosphatase GDA1/CD39 // 2.3E-115"
"209474_s_at",2.898897481,2.349326869,1.313025698,"UP","U87967","chr10:97515966-97626282 (+) // 100.0 // q24.1","ectonucleoside triphosphate diphosphohydrolase 1","ENTPD1","ENSG00000138185 /// OTTHUMG00000018818","953","601752 /// 615683","NP_001091645 /// NP_001157650 /// NP_001157651 /// NP_001157653 /// NP_001157654 /// NP_001157655 /// NP_001767 /// XP_006718139 /// XP_006718140","NM_001098175 /// NM_001164178 /// NM_001164179 /// NM_001164181 /// NM_001164182 /// NM_001164183 /// NM_001776 /// XM_006718076 /// XM_006718077","0006200 // ATP catabolic process // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009181 // purine ribonucleoside diphosphate catabolic process // inferred from electronic annotation /// 0030168 // platelet activation // inferred from electronic annotation","0005605 // basal lamina // inferred from electronic annotation /// 0005886 // plasma membrane // non-traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017110 // nucleoside-diphosphatase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation","---","IPR000407 // Nucleoside phosphatase GDA1/CD39 // 7.7E-162 /// IPR000407 // Nucleoside phosphatase GDA1/CD39 // 7.4E-162 /// IPR000407 // Nucleoside phosphatase GDA1/CD39 // 8.0E-162 /// IPR000407 // Nucleoside phosphatase GDA1/CD39 // 2.4E-133 /// IPR000407 // Nucleoside phosphatase GDA1/CD39 // 2.3E-115"
"209515_s_at",1.31456392,1.392807664,1.290166562,"UP","U38654","chr15:55496137-55562585 (-) // 95.23 // q21.3","RAB27A, member RAS oncogene family","RAB27A","ENSG00000069974 /// OTTHUMG00000131959","5873","603868 /// 607624","NP_004571 /// NP_899057 /// NP_899058 /// NP_899059 /// XP_005254633 /// XP_005254634","NM_004580 /// NM_183234 /// NM_183235 /// NM_183236 /// XM_005254576 /// XM_005254577","0006184 // GTP catabolic process // inferred from electronic annotation /// 0006605 // protein targeting // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from mutant phenotype /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0032400 // melanosome localization // inferred from electronic annotation /// 0032402 // melanosome transport // inferred from electronic annotation /// 0043316 // cytotoxic T cell degranulation // inferred from electronic annotation /// 0043320 // natural killer cell degranulation // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045921 // positive regulation of exocytosis // inferred from mutant phenotype /// 0051875 // pigment granule localization // inferred from electronic annotation /// 0051904 // pigment granule transport // inferred from electronic annotation /// 0071985 // multivesicular body sorting pathway // inferred from mutant phenotype","0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0030425 // dendrite // inferred from direct assay /// 0030667 // secretory granule membrane // inferred from electronic annotation /// 0032585 // multivesicular body membrane // inferred from direct assay /// 0042470 // melanosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070382 // exocytic vesicle // inferred from direct assay","0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0005525 // GTP binding // inferred from sequence or structural similarity /// 0019003 // GDP binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031489 // myosin V binding // inferred from electronic annotation","---","IPR000795 // Elongation factor, GTP-binding domain // 2.4E-9 /// IPR001806 // Small GTPase superfamily // 8.3E-60 /// IPR006689 // Small GTPase superfamily, ARF/SAR type // 7.1E-15 /// IPR013684 // Mitochondrial Rho-like // 9.8E-20"
"209612_s_at",-3.53128843,-2.299446103,-1.363294868,"DOWN","M24317","chr4:100228536-100242518 (-) // 99.69 // q23","alcohol dehydrogenase 1B (class I), beta polypeptide","ADH1B","ENSG00000196616 /// OTTHUMG00000161413","125","103720 /// 103780","NP_000659 /// NP_001273579 /// XP_006714142","NM_000668 /// NM_001286650 /// XM_006714079","0006069 // ethanol oxidation // inferred from direct assay /// 0006069 // ethanol oxidation // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation","0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement","0004022 // alcohol dehydrogenase (NAD) activity // inferred from electronic annotation /// 0004024 // alcohol dehydrogenase activity, zinc-dependent // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR013149 // Alcohol dehydrogenase, C-terminal // 1.9E-28 /// IPR013149 // Alcohol dehydrogenase, C-terminal // 1.5E-28 /// IPR013154 // Alcohol dehydrogenase GroES-like // 5.1E-32 /// IPR013154 // Alcohol dehydrogenase GroES-like // 3.5E-29"
"209613_s_at",-3.848848684,-2.395382263,-2.737977085,"DOWN","M21692","chr4:100227740-100242520 (-) // 97.68 // q23","alcohol dehydrogenase 1B (class I), beta polypeptide","ADH1B","ENSG00000196616 /// OTTHUMG00000161413","125","103720 /// 103780","NP_000659 /// NP_001273579 /// XP_006714142","NM_000668 /// NM_001286650 /// XM_006714079","0006069 // ethanol oxidation // inferred from direct assay /// 0006069 // ethanol oxidation // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation","0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement","0004022 // alcohol dehydrogenase (NAD) activity // inferred from electronic annotation /// 0004024 // alcohol dehydrogenase activity, zinc-dependent // inferred from direct assay /// 0008270 // zinc ion binding // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR013149 // Alcohol dehydrogenase, C-terminal // 1.9E-28 /// IPR013149 // Alcohol dehydrogenase, C-terminal // 1.5E-28 /// IPR013154 // Alcohol dehydrogenase GroES-like // 5.1E-32 /// IPR013154 // Alcohol dehydrogenase GroES-like // 3.5E-29"
"209687_at",-1.547529352,-1.540735727,-1.155113581,"DOWN","U19495","chr10:44872580-44880557 (-) // 81.46 // q11.21","chemokine (C-X-C motif) ligand 12","CXCL12","ENSG00000107562 /// OTTHUMG00000018054","6387","600835 /// 609423","NP_000600 /// NP_001029058 /// NP_001171605 /// NP_001264919 /// NP_954637","NM_000609 /// NM_001033886 /// NM_001178134 /// NM_001277990 /// NM_199168","0001569 // patterning of blood vessels // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001667 // ameboidal cell migration // inferred from electronic annotation /// 0001764 // neuron migration // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred from electronic annotation /// 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007281 // germ cell development // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008015 // blood circulation // traceable author statement /// 0008045 // motor neuron axon guidance // inferred from electronic annotation /// 0008064 // regulation of actin polymerization or depolymerization // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0008354 // germ cell migration // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation /// 0009408 // response to heat // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009615 // response to virus // traceable author statement /// 0022029 // telencephalon cell migration // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0033603 // positive regulation of dopamine secretion // inferred from electronic annotation /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred from direct assay /// 0048842 // positive regulation of axon extension involved in axon guidance // inferred from electronic annotation /// 0050930 // induction of positive chemotaxis // inferred from electronic annotation /// 0051924 // regulation of calcium ion transport // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement /// 0070098 // chemokine-mediated signaling pathway // inferred from direct assay /// 0090026 // positive regulation of monocyte chemotaxis // inferred from direct assay /// 0090280 // positive regulation of calcium ion import // traceable author statement /// 1902230 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 2000107 // negative regulation of leukocyte apoptotic process // inferred from direct assay /// 2000406 // positive regulation of T cell migration // inferred from direct assay","0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // traceable author statement /// 0008083 // growth factor activity // inferred from electronic annotation /// 0042379 // chemokine receptor binding // inferred from mutant phenotype /// 0045236 // CXCR chemokine receptor binding // inferred from direct assay","---","IPR001811 // Chemokine interleukin-8-like domain // 1.6E-14 /// IPR001811 // Chemokine interleukin-8-like domain // 5.3E-14"
"209695_at",1.556250107,1.221802148,1.630481678,"UP","BC003105","chr8:142432006-142441620 (+) // 94.58 // q24.3","protein tyrosine phosphatase type IVA, member 3","PTP4A3","ENSG00000184489 /// OTTHUMG00000164490","11156","606449","NP_009010 /// NP_116000 /// XP_005250819 /// XP_005250820 /// XP_005250821 /// XP_005250823 /// XP_005250824 /// XP_006716562 /// XP_006716563 /// XP_006725163 /// XP_006725164 /// XP_006725165 /// XP_006725166","NM_007079 /// NM_032611 /// XM_005250762 /// XM_005250763 /// XM_005250764 /// XM_005250766 /// XM_005250767 /// XM_006716499 /// XM_006716500 /// XM_006725100 /// XM_006725101 /// XM_006725102 /// XM_006725103","0006470 // protein dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // traceable author statement","0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation","0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004727 // prenylated protein tyrosine phosphatase activity // traceable author statement /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation","---","IPR000242 // Protein-tyrosine phosphatase, receptor/non-receptor type // 5.9E-12 /// IPR000340 // Dual specificity phosphatase, catalytic domain // 2.6E-12"
"209699_x_at",-1.579134885,-1.092977698,-1.629433356,"DOWN","U05598","chr10:5005619-5020158 (+) // 97.21 // p15.1 /// chr10:5031964-5046050 (-) // 99.84 // p15.1","aldo-keto reductase family 1, member C2 /// aldo-keto reductase family 1 member C2-like","AKR1C2 /// LOC101930400","ENSG00000151632 /// OTTHUMG00000017584","1646 /// 101930400","600450 /// 614279","NP_001128713 /// NP_001345 /// NP_995317 /// XP_005276151","NM_001135241 /// NM_001354 /// NM_205845 /// XM_005276094","0006629 // lipid metabolic process // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from direct assay /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007586 // digestion // inferred from direct assay /// 0008202 // steroid metabolic process // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0034694 // response to prostaglandin // inferred from direct assay /// 0042448 // progesterone metabolic process // inferred from direct assay /// 0044597 // daunorubicin metabolic process // inferred from mutant phenotype /// 0044598 // doxorubicin metabolic process // inferred from mutant phenotype /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0071395 // cellular response to jasmonic acid stimulus // inferred from direct assay","0005737 // cytoplasm // inferred from electronic annotation","0004032 // alditol:NADP+ 1-oxidoreductase activity // inferred from direct assay /// 0004958 // prostaglandin F receptor activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016655 // oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor // inferred from direct assay /// 0018636 // phenanthrene 9,10-monooxygenase activity // inferred from direct assay /// 0031406 // carboxylic acid binding // inferred from direct assay /// 0032052 // bile acid binding // inferred from direct assay /// 0047086 // ketosteroid monooxygenase activity // inferred from direct assay /// 0047115 // trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity // inferred from direct assay","---","IPR023210 // NADP-dependent oxidoreductase domain // 6.9E-65 /// IPR023210 // NADP-dependent oxidoreductase domain // 5.0E-61"
"209737_at",-1.34057743,-1.269820601,-1.13560136,"DOWN","AB014605","chr7:77646397-78400403 (-) // 94.53 // q21.11","membrane associated guanylate kinase, WW and PDZ domain containing 2","MAGI2","ENSG00000187391 /// OTTHUMG00000130697","9863","606382","NP_036433 /// XP_005250782","NM_012301 /// XM_005250725","0002092 // positive regulation of receptor internalization // inferred from direct assay /// 0003402 // planar cell polarity pathway involved in axis elongation // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016482 // cytoplasmic transport // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0032516 // positive regulation of phosphoprotein phosphatase activity // inferred from direct assay /// 0032926 // negative regulation of activin receptor signaling pathway // inferred from sequence or structural similarity /// 0038180 // nerve growth factor signaling pathway // inferred from sequence or structural similarity /// 0043113 // receptor clustering // inferred from sequence or structural similarity /// 0051291 // protein heterooligomerization // inferred from sequence or structural similarity /// 0051898 // negative regulation of protein kinase B signaling // inferred from direct assay /// 0060395 // SMAD protein signal transduction // inferred from sequence or structural similarity /// 0071850 // mitotic cell cycle arrest // inferred from sequence or structural similarity /// 0072015 // glomerular visceral epithelial cell development // inferred from sequence or structural similarity /// 1990090 // cellular response to nerve growth factor stimulus // inferred from sequence or structural similarity","0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0005923 // tight junction // inferred from direct assay /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0036057 // slit diaphragm // inferred from sequence or structural similarity /// 0043005 // neuron projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity","0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from physical interaction /// 0030159 // receptor signaling complex scaffold activity // inferred from direct assay /// 0031697 // beta-1 adrenergic receptor binding // inferred from physical interaction /// 0046332 // SMAD binding // inferred from sequence or structural similarity /// 0070699 // type II activin receptor binding // inferred from sequence or structural similarity","---","IPR001202 // WW domain // 8.1E-15 /// IPR001202 // WW domain // 1.7E-12 /// IPR001202 // WW domain // 8.2E-15 /// IPR001202 // WW domain // 1.8E-15 /// IPR001202 // WW domain // 3.7E-13 /// IPR001478 // PDZ domain // 3.4E-9 /// IPR001478 // PDZ domain // 1.7E-12 /// IPR001478 // PDZ domain // 9.2E-10 /// IPR001478 // PDZ domain // 1.6E-11 /// IPR001478 // PDZ domain // 4.8E-17 /// IPR001478 // PDZ domain // 9.4E-19 /// IPR001478 // PDZ domain // 1.8E-12 /// IPR001478 // PDZ domain // 9.3E-10 /// IPR001478 // PDZ domain // 1.6E-11 /// IPR001478 // PDZ domain // 4.8E-17 /// IPR001478 // PDZ domain // 9.5E-19 /// IPR001478 // PDZ domain // 3.4E-13 /// IPR001478 // PDZ domain // 2.2E-10 /// IPR008145 // Guanylate kinase/L-type calcium channel beta subunit // 5.0E-14"
"209792_s_at",1.916987118,2.174854039,4.185619386,"UP","BC002710","chr19:51517596-51523282 (-) // 85.73 // q13.41","kallikrein-related peptidase 10","KLK10","ENSG00000129451 /// OTTHUMG00000182916","5655","602673","NP_001070968 /// NP_002767 /// NP_665895 /// XP_005259118 /// XP_005259119 /// XP_006723350 /// XP_006723351 /// XP_006723352","NM_001077500 /// NM_002776 /// NM_145888 /// XM_005259061 /// XM_005259062 /// XM_006723287 /// XM_006723288 /// XM_006723289","0006508 // proteolysis // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation","0005576 // extracellular region // inferred from electronic annotation","0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation","---","IPR001254 // Peptidase S1 // 3.4E-62"
"209803_s_at",1.822126694,1.660248974,1.359520094,"UP","AF001294","chr11:2949662-2950650 (-) // 100.0 // p15.4","pleckstrin homology-like domain, family A, member 2","PHLDA2","ENSG00000181649 /// OTTHUMG00000010926","7262","602131","NP_003302","NM_003311","0001890 // placenta development // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0045995 // regulation of embryonic development // inferred from electronic annotation /// 0070873 // regulation of glycogen metabolic process // inferred from electronic annotation","0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation","0005543 // phospholipid binding // inferred from electronic annotation","---","IPR001849 // Pleckstrin homology domain // 1.1E-9"
"209810_at",2.514446859,3.501219406,3.302743651,"UP","J02761","chr2:85885986-85895312 (-) // 97.78 // p11.2","surfactant protein B","SFTPB","ENSG00000168878 /// OTTHUMG00000130181","6439","178640 /// 265120","NP_000533 /// NP_942140 /// XP_005264544 /// XP_005264545 /// XP_005264546 /// XP_005264547 /// XP_006712139","NM_000542 /// NM_198843 /// XM_005264487 /// XM_005264488 /// XM_005264489 /// XM_005264490 /// XM_006712076","0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement","0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation","---","---","IPR003119 // Saposin type A // 1.7E-18 /// IPR003119 // Saposin type A // 1.8E-18 /// IPR007856 // Saposin-like type B, 1 // 3.8E-9 /// IPR007856 // Saposin-like type B, 1 // 4.0E-9 /// IPR008138 // Saposin-like type B, 2 // 5.7E-14 /// IPR008138 // Saposin-like type B, 2 // 6.1E-8 /// IPR008138 // Saposin-like type B, 2 // 2.7E-14 /// IPR008138 // Saposin-like type B, 2 // 6.0E-14 /// IPR008138 // Saposin-like type B, 2 // 6.3E-8 /// IPR008138 // Saposin-like type B, 2 // 2.8E-14"
"209822_s_at",-1.221989504,-1.280522234,-1.152690721,"DOWN","L22431","chr9:2622079-2654463 (+) // 98.14 // p24.2","very low density lipoprotein receptor","VLDLR","ENSG00000147852 /// OTTHUMG00000019447","7436","192977 /// 224050","NP_001018066 /// NP_003374 /// XP_006716927 /// XP_006716928","NM_001018056 /// NM_003383 /// XM_006716864 /// XM_006716865","0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007613 // memory // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0021517 // ventral spinal cord development // inferred from electronic annotation /// 0034436 // glycoprotein transport // inferred from direct assay /// 0034447 // very-low-density lipoprotein particle clearance // inferred from direct assay /// 0038026 // reelin-mediated signaling pathway // inferred from sequence or structural similarity /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 1900006 // positive regulation of dendrite development // inferred from sequence or structural similarity","0005615 // extracellular space // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0034361 // very-low-density lipoprotein particle // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay","0001948 // glycoprotein binding // inferred from physical interaction /// 0005041 // low-density lipoprotein receptor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030229 // very-low-density lipoprotein particle receptor activity // inferred from direct assay /// 0034185 // apolipoprotein binding // inferred from direct assay /// 0034185 // apolipoprotein binding // inferred from sequence or structural similarity /// 0034189 // very-low-density lipoprotein particle binding // inferred from direct assay /// 0034437 // glycoprotein transporter activity // inferred from direct assay /// 0038025 // reelin receptor activity // inferred from sequence or structural similarity /// 0048306 // calcium-dependent protein binding // inferred from physical interaction","---","IPR000033 // LDLR class B repeat // 9.2E-14 /// IPR000033 // LDLR class B repeat // 1.6E-16 /// IPR000033 // LDLR class B repeat // 8.4E-20 /// IPR000033 // LDLR class B repeat // 7.0E-14 /// IPR000033 // LDLR class B repeat // 1.3E-10 /// IPR000033 // LDLR class B repeat // 8.9E-14 /// IPR000033 // LDLR class B repeat // 8.1E-20 /// IPR000033 // LDLR class B repeat // 6.8E-14 /// IPR000033 // LDLR class B repeat // 1.2E-10 /// IPR001881 // EGF-like calcium-binding domain // 1.5E-11 /// IPR001881 // EGF-like calcium-binding domain // 1.4E-11 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.3E-18 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 9.5E-16 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.8E-13 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 3.1E-16 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.4E-16 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 5.4E-17 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 2.7E-15 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 5.1E-14 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 9.2E-16 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.7E-13 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 2.9E-16 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.3E-16 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 5.2E-17 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 2.6E-15 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 4.9E-14"
"209875_s_at",2.832530537,1.651579623,1.240883094,"UP","M83248","chr4:88896869-88904284 (+) // 99.69 // q22.1","secreted phosphoprotein 1","SPP1","ENSG00000118785 /// OTTHUMG00000130599","6696","166490","NP_000573 /// NP_001035147 /// NP_001035149 /// NP_001238758 /// NP_001238759","NM_000582 /// NM_001040058 /// NM_001040060 /// NM_001251829 /// NM_001251830","0001503 // ossification // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007566 // embryo implantation // traceable author statement /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030593 // neutrophil chemotaxis // inferred from electronic annotation /// 0031214 // biomineral tissue development // inferred from electronic annotation /// 0033280 // response to vitamin D // inferred from direct assay /// 0045780 // positive regulation of bone resorption // inferred from electronic annotation /// 0046697 // decidualization // traceable author statement /// 0048545 // response to steroid hormone // inferred from electronic annotation /// 0048685 // negative regulation of collateral sprouting of intact axon in response to injury // inferred from electronic annotation","0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031988 // membrane-bounded vesicle // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0050840 // extracellular matrix binding // inferred from electronic annotation","TGF_Beta_Signaling_Pathway // GenMAPP","IPR002038 // Osteopontin // 5.7E-156 /// IPR002038 // Osteopontin // 1.3E-173 /// IPR002038 // Osteopontin // 3.7E-17 /// IPR002038 // Osteopontin // 2.0E-133"
"209924_at",1.404457428,1.983456252,1.601986713,"UP","AB000221","chr17:34391639-34398828 (+) // 100.0 // q12","chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)","CCL18","---","6362","603757","NP_002979","NM_002988","0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007154 // cell communication // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0009607 // response to biotic stimulus // traceable author statement /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement","0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation","0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008009 // chemokine activity // inferred from electronic annotation","---","---"
"209969_s_at",1.646607735,1.229561531,1.109881091,"UP","BC002704","chr2:191840367-191878894 (-) // 98.98 // q32.2","signal transducer and activator of transcription 1, 91kDa","STAT1","ENSG00000115415 /// OTTHUMG00000132699","6772","209950 /// 600555 /// 613796 /// 614162","NP_009330 /// NP_644671 /// XP_006712781","NM_007315 /// NM_139266 /// XM_006712718","0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002053 // positive regulation of mesenchymal cell proliferation // inferred from sequence or structural similarity /// 0003340 // negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0006915 // apoptotic process // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007259 // JAK-STAT cascade // inferred from direct assay /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008015 // blood circulation // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009617 // response to bacterium // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from mutant phenotype /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0034097 // response to cytokine // inferred from sequence or structural similarity /// 0034240 // negative regulation of macrophage fusion // inferred from electronic annotation /// 0035458 // cellular response to interferon-beta // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043330 // response to exogenous dsRNA // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from sequence or structural similarity /// 0043542 // endothelial cell migration // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from sequence or structural similarity /// 0051591 // response to cAMP // inferred from sequence or structural similarity /// 0051607 // defense response to virus // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // inferred from direct assay /// 0060333 // interferon-gamma-mediated signaling pathway // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // inferred from sequence or structural similarity /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0060338 // regulation of type I interferon-mediated signaling pathway // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 0061326 // renal tubule development // inferred from mutant phenotype /// 0072136 // metanephric mesenchymal cell proliferation involved in metanephros development // inferred from sequence or structural similarity /// 0072162 // metanephric mesenchymal cell differentiation // inferred from sequence or structural similarity /// 0072308 // negative regulation of metanephric nephron tubule epithelial cell differentiation // inferred from sequence or structural similarity","0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030424 // axon // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity","0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0000979 // RNA polymerase II core promoter sequence-specific DNA binding // inferred from direct assay /// 0000983 // RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // inferred from physical interaction /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0031730 // CCR5 chemokine receptor binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation","---","IPR000980 // SH2 domain // 1.7E-12 /// IPR000980 // SH2 domain // 1.7E-12 /// IPR013799 // STAT transcription factor, protein interaction // 8.5E-47 /// IPR013799 // STAT transcription factor, protein interaction // 2.8E-48 /// IPR013799 // STAT transcription factor, protein interaction // 8.5E-47 /// IPR013800 // STAT transcription factor, all-alpha // 2.7E-68 /// IPR013800 // STAT transcription factor, all-alpha // 6.5E-16 /// IPR013800 // STAT transcription factor, all-alpha // 2.7E-68 /// IPR013801 // STAT transcription factor, DNA-binding // 1.1E-123 /// IPR013801 // STAT transcription factor, DNA-binding // 1.1E-123"
"209990_s_at",1.750238736,1.971554931,2.080837368,"UP","AF056085","chr9:101050365-101471479 (-) // 91.03 // q22.33","gamma-aminobutyric acid (GABA) B receptor, 2","GABBR2","ENSG00000136928 /// OTTHUMG00000020345","9568","188890 /// 607340","NP_005449 /// XP_005252373","NM_005458 /// XM_005252316","0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement /// 0007214 // gamma-aminobutyric acid signaling pathway // inferred from direct assay /// 0007268 // synaptic transmission // traceable author statement","0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0038039 // G-protein coupled receptor heterodimeric complex // inferred from physical interaction /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation","0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0004965 // G-protein coupled GABA receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction","GPCRDB_Class_C_Metabotropic_glutamate_pheromone // GenMAPP","IPR001828 // Extracellular ligand-binding receptor // 1.8E-50 /// IPR017978 // GPCR, family 3, C-terminal // 1.3E-59"
"209992_at",-1.267329186,-1.278094208,-1.09631137,"DOWN","AB044805","chr1:207226669-207253988 (+) // 99.81 // q32.2","6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2","PFKFB2","ENSG00000123836 /// OTTHUMG00000036033","5208","171835","NP_001018063 /// NP_006203 /// XP_005273219 /// XP_006711444 /// XP_006711445","NM_001018053 /// NM_006212 /// XM_005273162 /// XM_006711381 /// XM_006711382","0005975 // carbohydrate metabolic process // traceable author statement /// 0006000 // fructose metabolic process // inferred from electronic annotation /// 0006003 // fructose 2,6-bisphosphate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // traceable author statement /// 0006007 // glucose catabolic process // inferred from electronic annotation /// 0006089 // lactate metabolic process // inferred from electronic annotation /// 0006090 // pyruvate metabolic process // inferred from electronic annotation /// 0006096 // glycolytic process // inferred from direct assay /// 0006096 // glycolytic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0033133 // positive regulation of glucokinase activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046835 // carbohydrate phosphorylation // inferred from direct assay /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // traceable author statement","0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement","0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003873 // 6-phosphofructo-2-kinase activity // inferred from direct assay /// 0004331 // fructose-2,6-bisphosphate 2-phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction","---","IPR013078 // Histidine phosphatase superfamily, clade-1 // 1.2E-39 /// IPR013079 // 6-phosphofructo-2-kinase // 2.7E-107 /// IPR013641 // Chromatin associated protein KTI12 // 3.1E-9"
"210038_at",-1.589375545,-1.047241413,-1.218753788,"DOWN","AL137145","chr10:6469104-6622263 (-) // 98.27 // p15.1","protein kinase C, theta","PRKCQ","ENSG00000065675 /// OTTHUMG00000017623","5588","600448","NP_001229342 /// NP_001269573 /// NP_001269574 /// NP_006248 /// XP_005252553 /// XP_005252554 /// XP_006717528","NM_001242413 /// NM_001282644 /// NM_001282645 /// NM_006257 /// XM_005252496 /// XM_005252497 /// XM_006717465","0001558 // regulation of cell growth // non-traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006509 // membrane protein ectodomain proteolysis // inferred from sequence or structural similarity /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0007603 // phototransduction, visible light // traceable author statement /// 0016056 // rhodopsin mediated signaling pathway // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016567 // protein ubiquitination // traceable author statement /// 0022400 // regulation of rhodopsin mediated signaling pathway // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0032740 // positive regulation of interleukin-17 production // inferred from sequence or structural similarity /// 0032753 // positive regulation of interleukin-4 production // inferred from sequence or structural similarity /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042102 // positive regulation of T cell proliferation // inferred from electronic annotation /// 0045086 // positive regulation of interleukin-2 biosynthetic process // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050870 // positive regulation of T cell activation // inferred from sequence or structural similarity /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0070233 // negative regulation of T cell apoptotic process // inferred from mutant phenotype /// 0090330 // regulation of platelet aggregation // inferred from sequence or structural similarity /// 2000318 // positive regulation of T-helper 17 type immune response // inferred from sequence or structural similarity /// 2000570 // positive regulation of T-helper 2 cell activation // inferred from sequence or structural similarity","0001772 // immunological synapse // inferred from electronic annotation /// 0005622 // intracellular // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation","0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // non-traceable author statement /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004697 // protein kinase C activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation","Calcium_regulation_in_cardiac_cells // GenMAPP /// G_Protein_Signaling // GenMAPP /// Smooth_muscle_contraction // GenMAPP /// Wnt_signaling // GenMAPP","IPR000719 // Protein kinase domain // 5.4E-71 /// IPR000719 // Protein kinase domain // 6.6E-51 /// IPR000719 // Protein kinase domain // 3.5E-71 /// IPR001245 // Serine-threonine/tyrosine-protein kinase catalytic domain // 1.5E-44 /// IPR001245 // Serine-threonine/tyrosine-protein kinase catalytic domain // 2.4E-30 /// IPR001245 // Serine-threonine/tyrosine-protein kinase catalytic domain // 9.8E-45 /// IPR002219 // Protein kinase C-like, phorbol ester/diacylglycerol-binding domain // 6.6E-18 /// IPR002219 // Protein kinase C-like, phorbol ester/diacylglycerol-binding domain // 3.7E-20 /// IPR002219 // Protein kinase C-like, phorbol ester/diacylglycerol-binding domain // 5.8E-18 /// IPR002219 // Protein kinase C-like, phorbol ester/diacylglycerol-binding domain // 3.3E-20 /// IPR002219 // Protein kinase C-like, phorbol ester/diacylglycerol-binding domain // 5.1E-18 /// IPR002219 // Protein kinase C-like, phorbol ester/diacylglycerol-binding domain // 2.9E-20 /// IPR017892 // Protein kinase, C-terminal // 3.2E-16 /// IPR017892 // Protein kinase, C-terminal // 2.8E-16 /// IPR017892 // Protein kinase, C-terminal // 2.5E-16"
"210078_s_at",-1.453228996,-1.82347729,-2.05916543,"DOWN","L39833","chr3:155860880-156256393 (+) // 98.96 // q25.31","potassium voltage-gated channel, shaker-related subfamily, beta member 1","KCNAB1","ENSG00000169282 /// OTTHUMG00000158552","7881","601141","NP_003462 /// NP_751891 /// NP_751892 /// XP_005247810 /// XP_005247811","NM_003471 /// NM_172159 /// NM_172160 /// XM_005247753 /// XM_005247754","0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 1901016 // regulation of potassium ion transmembrane transporter activity // inferred from electronic annotation","0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation","0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015459 // potassium channel regulator activity // traceable author statement","---","IPR023210 // NADP-dependent oxidoreductase domain // 6.4E-76 /// IPR023210 // NADP-dependent oxidoreductase domain // 5.9E-76 /// IPR023210 // NADP-dependent oxidoreductase domain // 5.5E-76"
"210194_at",-1.722848287,-1.014464987,-2.402781757,"DOWN","U17033","chr2:160797259-160919121 (-) // 98.53 // q24.2","phospholipase A2 receptor 1, 180kDa","PLA2R1","---","22925","604939","NP_001007268 /// NP_001182570 /// NP_031392 /// XP_005246449 /// XP_005246450 /// XP_005246452 /// XP_006712432","NM_001007267 /// NM_001195641 /// NM_007366 /// XM_005246392 /// XM_005246393 /// XM_005246395 /// XM_006712369","0001816 // cytokine production // inferred from mutant phenotype /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0043517 // positive regulation of DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype /// 0072593 // reactive oxygen species metabolic process // inferred from direct assay /// 0090238 // positive regulation of arachidonic acid secretion // inferred from sequence or structural similarity /// 0090399 // replicative senescence // inferred from mutant phenotype /// 0090403 // oxidative stress-induced premature senescence // inferred from mutant phenotype /// 1900138 // negative regulation of phospholipase A2 activity // inferred from sequence or structural similarity /// 1900139 // negative regulation of arachidonic acid secretion // inferred from sequence or structural similarity","0005576 // extracellular region // inferred from sequence or structural similarity /// 0005576 // extracellular region // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0004872 // receptor activity // inferred from direct assay /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0043274 // phospholipase binding // inferred from electronic annotation /// 0043274 // phospholipase binding // inferred from physical interaction","---","---"
"210298_x_at",-2.022541663,-2.60244077,-2.348639306,"DOWN","AF098518","chrX:135252112-135292184 (+) // 99.82 // q26.3","four and a half LIM domains 1","FHL1","ENSG00000022267 /// OTTHUMG00000022504","2273","300163 /// 300695 /// 300696 /// 300717 /// 300718","NP_001153171 /// NP_001153172 /// NP_001153173 /// NP_001153174 /// NP_001153175 /// NP_001153176 /// NP_001161291 /// NP_001440 /// XP_006724806 /// XP_006724807 /// XP_006724808 /// XP_006724809 /// XP_006724810","NM_001159699 /// NM_001159700 /// NM_001159701 /// NM_001159702 /// NM_001159703 /// NM_001159704 /// NM_001167819 /// NM_001449 /// NR_027621 /// XM_006724743 /// XM_006724744 /// XM_006724745 /// XM_006724746 /// XM_006724747","0003254 // regulation of membrane depolarization // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // non-traceable author statement /// 0009887 // organ morphogenesis // non-traceable author statement /// 0010972 // negative regulation of G2/M transition of mitotic cell cycle // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 1901016 // regulation of potassium ion transmembrane transporter activity // inferred from direct assay /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from direct assay","0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay","0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR001781 // Zinc finger, LIM-type // 6.6E-15 /// IPR001781 // Zinc finger, LIM-type // 8.1E-16 /// IPR001781 // Zinc finger, LIM-type // 1.2E-15"
"210299_s_at",-1.954633483,-2.4519219,-2.376532164,"DOWN","AF063002","chrX:135252084-135293103 (+) // 97.7 // q26.3","four and a half LIM domains 1","FHL1","ENSG00000022267 /// OTTHUMG00000022504","2273","300163 /// 300695 /// 300696 /// 300717 /// 300718","NP_001153171 /// NP_001153172 /// NP_001153173 /// NP_001153174 /// NP_001153175 /// NP_001153176 /// NP_001161291 /// NP_001440 /// XP_006724806 /// XP_006724807 /// XP_006724808 /// XP_006724809 /// XP_006724810","NM_001159699 /// NM_001159700 /// NM_001159701 /// NM_001159702 /// NM_001159703 /// NM_001159704 /// NM_001167819 /// NM_001449 /// NR_027621 /// XM_006724743 /// XM_006724744 /// XM_006724745 /// XM_006724746 /// XM_006724747","0003254 // regulation of membrane depolarization // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle organ development // non-traceable author statement /// 0009887 // organ morphogenesis // non-traceable author statement /// 0010972 // negative regulation of G2/M transition of mitotic cell cycle // inferred from direct assay /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0043268 // positive regulation of potassium ion transport // inferred from direct assay /// 1901016 // regulation of potassium ion transmembrane transporter activity // inferred from direct assay /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from direct assay","0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay","0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044325 // ion channel binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR001781 // Zinc finger, LIM-type // 5.2E-15 /// IPR001781 // Zinc finger, LIM-type // 6.4E-16 /// IPR001781 // Zinc finger, LIM-type // 9.6E-16 /// IPR001781 // Zinc finger, LIM-type // 5.2E-14 /// IPR001781 // Zinc finger, LIM-type // 6.6E-15 /// IPR001781 // Zinc finger, LIM-type // 8.1E-16 /// IPR001781 // Zinc finger, LIM-type // 1.2E-15 /// IPR001781 // Zinc finger, LIM-type // 5.7E-15 /// IPR001781 // Zinc finger, LIM-type // 7.1E-16 /// IPR001781 // Zinc finger, LIM-type // 1.0E-15 /// IPR001781 // Zinc finger, LIM-type // 5.7E-14 /// IPR001781 // Zinc finger, LIM-type // 6.1E-15 /// IPR001781 // Zinc finger, LIM-type // 7.6E-16 /// IPR001781 // Zinc finger, LIM-type // 1.1E-15 /// IPR001781 // Zinc finger, LIM-type // 6.1E-14"
"210342_s_at",-3.943443299,-3.186630958,-4.230122713,"DOWN","M17755","chr2:1417235-1546420 (+) // 99.64 // p25.3","thyroid peroxidase","TPO","ENSG00000115705 /// OTTHUMG00000090271","7173","274500 /// 606765","NP_000538 /// NP_001193673 /// NP_001193674 /// NP_783650 /// NP_783652 /// NP_783653 /// XP_005264755 /// XP_005264756 /// XP_005264757 /// XP_005264758 /// XP_005264759 /// XP_005264761 /// XP_005264762","NM_000547 /// NM_001206744 /// NM_001206745 /// NM_175719 /// NM_175720 /// NM_175721 /// NM_175722 /// XM_005264698 /// XM_005264699 /// XM_005264700 /// XM_005264701 /// XM_005264702 /// XM_005264704 /// XM_005264705 /// XR_426959","0006590 // thyroid hormone generation // inferred from electronic annotation /// 0006590 // thyroid hormone generation // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0035162 // embryonic hemopoiesis // inferred from direct assay /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0042744 // hydrogen peroxide catabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation","0005615 // extracellular space // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0004447 // iodide peroxidase activity // inferred from electronic annotation /// 0004601 // peroxidase activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000436 // Sushi/SCR/CCP // 9.8E-8 /// IPR000742 // Epidermal growth factor-like domain // 3.5E-9 /// IPR001881 // EGF-like calcium-binding domain // 1.3E-14 /// IPR001881 // EGF-like calcium-binding domain // 1.2E-14 /// IPR001881 // EGF-like calcium-binding domain // 1.4E-14 /// IPR001881 // EGF-like calcium-binding domain // 6.7E-16"
"210471_s_at",-1.535195549,-1.514347701,-1.260765906,"DOWN","U33428","chr3:156009669-156255923 (+) // 98.93 // q25.31","potassium voltage-gated channel, shaker-related subfamily, beta member 1","KCNAB1","ENSG00000169282 /// OTTHUMG00000158552","7881","601141","NP_003462 /// NP_751891 /// NP_751892 /// XP_005247810 /// XP_005247811","NM_003471 /// NM_172159 /// NM_172160 /// XM_005247753 /// XM_005247754","0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007611 // learning or memory // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation /// 1901016 // regulation of potassium ion transmembrane transporter activity // inferred from electronic annotation","0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation","0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0015459 // potassium channel regulator activity // traceable author statement","---","IPR023210 // NADP-dependent oxidoreductase domain // 6.4E-76 /// IPR023210 // NADP-dependent oxidoreductase domain // 5.9E-76 /// IPR023210 // NADP-dependent oxidoreductase domain // 5.5E-76"
"210473_s_at",-1.602362514,-1.662084187,-1.570044748,"DOWN","M37712","chr4:22389006-22403181 (-) // 49.47 // p15.2","G protein-coupled receptor 125","GPR125","ENSG00000152990 /// OTTHUMG00000160926","166647","612303","NP_660333 /// XP_005248194","NM_145290 /// XM_005248137","0001558 // regulation of cell growth // inferred from expression pattern /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006915 // apoptotic process // non-traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0050684 // regulation of mRNA processing // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation","0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004693 // cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay","---","IPR000203 // GPS motif // 8.6E-12 /// IPR000832 // GPCR, family 2, secretin-like // 3.4E-18 /// IPR001611 // Leucine-rich repeat // 6.7E-5 /// IPR001611 // Leucine-rich repeat // 2.1E-4 /// IPR001879 // GPCR, family 2, extracellular hormone receptor domain // 6.2E-8 /// IPR013098 // Immunoglobulin I-set // 2.9E-9"
"210495_x_at",3.011731042,2.576954386,2.703746345,"UP","AF130095","chr2:216225588-216240415 (-) // 89.45 // q35","fibronectin 1","FN1","ENSG00000115414 /// OTTHUMG00000133054","2335","135600 /// 601894 /// 614101","NP_002017 /// NP_473375 /// NP_997639 /// NP_997641 /// NP_997643 /// NP_997647 /// XP_005246454 /// XP_005246455 /// XP_005246456 /// XP_005246457 /// XP_005246458 /// XP_005246459 /// XP_005246460 /// XP_005246461 /// XP_005246462 /// XP_005246463 /// XP_005246464 /// XP_005246465 /// XP_005246466 /// XP_005246467 /// XP_005246468 /// XP_005246469 /// XP_005246470 /// XP_005246471 /// XP_005246472 /// XP_005246473 /// XP_005246474","NM_002026 /// NM_054034 /// NM_212474 /// NM_212475 /// NM_212476 /// NM_212478 /// NM_212482 /// XM_005246397 /// XM_005246398 /// XM_005246399 /// XM_005246400 /// XM_005246401 /// XM_005246402 /// XM_005246403 /// XM_005246404 /// XM_005246405 /// XM_005246406 /// XM_005246407 /// XM_005246408 /// XM_005246409 /// XM_005246410 /// XM_005246411 /// XM_005246412 /// XM_005246413 /// XM_005246414 /// XM_005246415 /// XM_005246416 /// XM_005246417","0001525 // angiogenesis // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007044 // cell-substrate junction assembly // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007161 // calcium-independent cell-matrix adhesion // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009611 // response to wounding // non-traceable author statement /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0016477 // cell migration // non-traceable author statement /// 0018149 // peptide cross-linking // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0042060 // wound healing // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement","0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay","0002020 // protease binding // inferred from physical interaction /// 0005178 // integrin binding // inferred from direct assay /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // non-traceable author statement /// 0008201 // heparin binding // non-traceable author statement /// 0016504 // peptidase activator activity // inferred from electronic annotation","Inflammatory_Response_Pathway // GenMAPP","IPR000083 // Fibronectin, type I // 2.0E-14 /// IPR000083 // Fibronectin, type I // 2.7E-18 /// IPR000083 // Fibronectin, type I // 1.6E-16 /// IPR000083 // Fibronectin, type I // 1.2E-18 /// IPR000083 // Fibronectin, type I // 3.5E-18 /// IPR000083 // Fibronectin, type I // 1.8E-12 /// IPR000083 // Fibronectin, type I // 1.5E-18 /// IPR000083 // Fibronectin, type I // 4.0E-16 /// IPR000083 // Fibronectin, type I // 5.3E-18 /// IPR000083 // Fibronectin, type I // 1.2E-18 /// IPR000083 // Fibronectin, type I // 8.3E-17 /// IPR000083 // Fibronectin, type I // 1.5E-13 /// IPR000083 // Fibronectin, type I // 2.2E-14 /// IPR000083 // Fibronectin, type I // 3.0E-18 /// IPR000083 // Fibronectin, type I // 1.8E-16 /// IPR000083 // Fibronectin, type I // 1.3E-18 /// IPR000083 // Fibronectin, type I // 3.9E-18 /// IPR000083 // Fibronectin, type I // 2.0E-12 /// IPR000083 // Fibronectin, type I // 1.6E-18 /// IPR000083 // Fibronectin, type I // 4.4E-16 /// IPR000083 // Fibronectin, type I // 5.9E-18 /// IPR000083 // Fibronectin, type I // 1.3E-18 /// IPR000083 // Fibronectin, type I // 9.2E-17 /// IPR000083 // Fibronectin, type I // 1.7E-13 /// IPR000083 // Fibronectin, type I // 2.1E-14 /// IPR000083 // Fibronectin, type I // 2.9E-18 /// IPR000083 // Fibronectin, type I // 1.7E-16 /// IPR000083 // Fibronectin, type I // 3.7E-18 /// IPR000083 // Fibronectin, type I // 4.3E-16 /// IPR000083 // Fibronectin, type I // 5.6E-18 /// IPR000083 // Fibronectin, type I // 1.3E-18 /// IPR000083 // Fibronectin, type I // 8.8E-17 /// IPR000083 // Fibronectin, type I // 1.6E-13 /// IPR000083 // Fibronectin, type I // 1.9E-14 /// IPR000083 // Fibronectin, type I // 2.6E-18 /// IPR000083 // Fibronectin, type I // 3.4E-18 /// IPR000083 // Fibronectin, type I // 1.4E-18 /// IPR000083 // Fibronectin, type I // 3.9E-16 /// IPR000083 // Fibronectin, type I // 5.2E-18 /// IPR000083 // Fibronectin, type I // 1.2E-18 /// IPR000083 // Fibronectin, type I // 8.1E-17 /// IPR000083 // Fibronectin, type I // 1.5E-13 /// IPR000083 // Fibronectin, type I // 1.4E-18 /// IPR000083 // Fibronectin, type I // 2.1E-12 /// IPR000083 // Fibronectin, type I // 1.7E-18 /// IPR000083 // Fibronectin, type I // 4.5E-16 /// IPR000083 // Fibronectin, type I // 1.4E-18 /// IPR000083 // Fibronectin, type I // 9.3E-17 /// IPR000083 // Fibronectin, type I // 1.7E-13 /// IPR000083 // Fibronectin, type I // 2.8E-18 /// IPR000083 // Fibronectin, type I // 1.9E-12 /// IPR000083 // Fibronectin, type I // 4.2E-16 /// IPR000083 // Fibronectin, type I // 1.3E-18 /// IPR000083 // Fibronectin, type I // 8.7E-17 /// IPR000083 // Fibronectin, type I // 1.6E-13 /// IPR000083 // Fibronectin, type I // 3.6E-18 /// IPR000083 // Fibronectin, type I // 4.1E-16 /// IPR000083 // Fibronectin, type I // 5.4E-18 /// IPR000083 // Fibronectin, type I // 1.2E-18 /// IPR000083 // Fibronectin, type I // 8.4E-17 /// IPR000083 // Fibronectin, type I // 1.5E-13 /// IPR000083 // Fibronectin, type I // 1.2E-18 /// IPR000083 // Fibronectin, type I // 8.4E-17 /// IPR000083 // Fibronectin, type I // 1.5E-13 /// IPR000083 // Fibronectin, type I // 5.5E-18 /// IPR000083 // Fibronectin, type I // 1.3E-18 /// IPR000083 // Fibronectin, type I // 8.6E-17 /// IPR000083 // Fibronectin, type I // 1.5E-13 /// IPR000083 // Fibronectin, type I // 3.8E-18 /// IPR000083 // Fibronectin, type I // 5.7E-18 /// IPR000083 // Fibronectin, type I // 1.3E-18 /// IPR000083 // Fibronectin, type I // 8.9E-17 /// IPR000083 // Fibronectin, type I // 1.6E-13 /// IPR000562 // Fibronectin, type II, collagen-binding // 1.1E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 6.5E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 1.2E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 7.2E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 6.9E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 6.3E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 7.3E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 6.8E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 6.6E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 6.7E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 7.0E-21 /// IPR003961 // Fibronectin, type III // 2.3E-15 /// IPR003961 // Fibronectin, type III // 5.2E-16 /// IPR003961 // Fibronectin, type III // 8.3E-22 /// IPR003961 // Fibronectin, type III // 2.1E-18 /// IPR003961 // Fibronectin, type III // 6.6E-19 /// IPR003961 // Fibronectin, type III // 6.0E-10 /// IPR003961 // Fibronectin, type III // 1.3E-16 /// IPR003961 // Fibronectin, type III // 3.7E-20 /// IPR003961 // Fibronectin, type III // 6.0E-20 /// IPR003961 // Fibronectin, type III // 4.9E-24 /// IPR003961 // Fibronectin, type III // 1.0E-20 /// IPR003961 // Fibronectin, type III // 1.1E-19 /// IPR003961 // Fibronectin, type III // 1.3E-18 /// IPR003961 // Fibronectin, type III // 4.0E-21 /// IPR003961 // Fibronectin, type III // 5.8E-11 /// IPR003961 // Fibronectin, type III // 2.5E-15 /// IPR003961 // Fibronectin, type III // 5.7E-16 /// IPR003961 // Fibronectin, type III // 9.1E-22 /// IPR003961 // Fibronectin, type III // 2.4E-18 /// IPR003961 // Fibronectin, type III // 7.3E-19 /// IPR003961 // Fibronectin, type III // 6.6E-10 /// IPR003961 // Fibronectin, type III // 1.4E-16 /// IPR003961 // Fibronectin, type III // 8.1E-16 /// IPR003961 // Fibronectin, type III // 4.1E-20 /// IPR003961 // Fibronectin, type III // 6.6E-20 /// IPR003961 // Fibronectin, type III // 5.4E-24 /// IPR003961 // Fibronectin, type III // 1.1E-20 /// IPR003961 // Fibronectin, type III // 1.1E-15 /// IPR003961 // Fibronectin, type III // 1.3E-19 /// IPR003961 // Fibronectin, type III // 1.4E-18 /// IPR003961 // Fibronectin, type III // 4.4E-21 /// IPR003961 // Fibronectin, type III // 6.4E-11 /// IPR003961 // Fibronectin, type III // 2.4E-15 /// IPR003961 // Fibronectin, type III // 5.5E-16 /// IPR003961 // Fibronectin, type III // 8.7E-22 /// IPR003961 // Fibronectin, type III // 2.3E-18 /// IPR003961 // Fibronectin, type III // 7.0E-19 /// IPR003961 // Fibronectin, type III // 6.3E-10 /// IPR003961 // Fibronectin, type III // 3.9E-20 /// IPR003961 // Fibronectin, type III // 6.4E-20 /// IPR003961 // Fibronectin, type III // 5.2E-24 /// IPR003961 // Fibronectin, type III // 1.1E-20 /// IPR003961 // Fibronectin, type III // 1.1E-15 /// IPR003961 // Fibronectin, type III // 1.2E-19 /// IPR003961 // Fibronectin, type III // 1.3E-18 /// IPR003961 // Fibronectin, type III // 4.2E-21 /// IPR003961 // Fibronectin, type III // 6.1E-11 /// IPR003961 // Fibronectin, type III // 2.2E-15 /// IPR003961 // Fibronectin, type III // 5.0E-16 /// IPR003961 // Fibronectin, type III // 8.0E-22 /// IPR003961 // Fibronectin, type III // 6.4E-19 /// IPR003961 // Fibronectin, type III // 5.8E-10 /// IPR003961 // Fibronectin, type III // 1.2E-16 /// IPR003961 // Fibronectin, type III // 3.6E-20 /// IPR003961 // Fibronectin, type III // 5.8E-20 /// IPR003961 // Fibronectin, type III // 4.7E-24 /// IPR003961 // Fibronectin, type III // 9.9E-21 /// IPR003961 // Fibronectin, type III // 1.2E-18 /// IPR003961 // Fibronectin, type III // 3.9E-21 /// IPR003961 // Fibronectin, type III // 8.4E-11 /// IPR003961 // Fibronectin, type III // 2.6E-15 /// IPR003961 // Fibronectin, type III // 5.8E-16 /// IPR003961 // Fibronectin, type III // 9.3E-22 /// IPR003961 // Fibronectin, type III // 7.4E-19 /// IPR003961 // Fibronectin, type III // 6.7E-10 /// IPR003961 // Fibronectin, type III // 8.3E-16 /// IPR003961 // Fibronectin, type III // 6.7E-20 /// IPR003961 // Fibronectin, type III // 5.5E-24 /// IPR003961 // Fibronectin, type III // 1.2E-20 /// IPR003961 // Fibronectin, type III // 1.2E-15 /// IPR003961 // Fibronectin, type III // 4.5E-21 /// IPR003961 // Fibronectin, type III // 9.0E-11 /// IPR003961 // Fibronectin, type III // 5.4E-16 /// IPR003961 // Fibronectin, type III // 8.6E-22 /// IPR003961 // Fibronectin, type III // 2.2E-18 /// IPR003961 // Fibronectin, type III // 6.9E-19 /// IPR003961 // Fibronectin, type III // 6.2E-10 /// IPR003961 // Fibronectin, type III // 6.3E-20 /// IPR003961 // Fibronectin, type III // 5.1E-24 /// IPR003961 // Fibronectin, type III // 6.0E-11 /// IPR003961 // Fibronectin, type III // 5.3E-16 /// IPR003961 // Fibronectin, type III // 8.4E-22 /// IPR003961 // Fibronectin, type III // 6.7E-19 /// IPR003961 // Fibronectin, type III // 6.1E-10 /// IPR003961 // Fibronectin, type III // 6.1E-20 /// IPR003961 // Fibronectin, type III // 1.2E-19 /// IPR003961 // Fibronectin, type III // 5.8E-11 /// IPR003961 // Fibronectin, type III // 7.5E-16 /// IPR003961 // Fibronectin, type III // 3.7E-20 /// IPR003961 // Fibronectin, type III // 6.1E-20 /// IPR003961 // Fibronectin, type III // 4.9E-24 /// IPR003961 // Fibronectin, type III // 1.0E-20 /// IPR003961 // Fibronectin, type III // 1.2E-19 /// IPR003961 // Fibronectin, type III // 1.3E-18 /// IPR003961 // Fibronectin, type III // 4.0E-21 /// IPR003961 // Fibronectin, type III // 8.8E-11 /// IPR003961 // Fibronectin, type III // 8.5E-22 /// IPR003961 // Fibronectin, type III // 6.8E-19 /// IPR003961 // Fibronectin, type III // 3.8E-20 /// IPR003961 // Fibronectin, type III // 6.2E-20 /// IPR003961 // Fibronectin, type III // 5.0E-24 /// IPR003961 // Fibronectin, type III // 4.1E-21 /// IPR003961 // Fibronectin, type III // 8.3E-11 /// IPR003961 // Fibronectin, type III // 5.6E-16 /// IPR003961 // Fibronectin, type III // 8.9E-22 /// IPR003961 // Fibronectin, type III // 7.1E-19 /// IPR003961 // Fibronectin, type III // 6.4E-10 /// IPR003961 // Fibronectin, type III // 4.0E-20 /// IPR003961 // Fibronectin, type III // 6.5E-20 /// IPR003961 // Fibronectin, type III // 1.4E-18 /// IPR003961 // Fibronectin, type III // 4.3E-21 /// IPR003961 // Fibronectin, type III // 8.7E-11"
"210524_x_at",-1.636535336,-1.495179269,-2.101715357,"DOWN","AF078844","chr17:61895118-61895671 (-) // 51.26 // q23.3","---","---","---","---","---","---","---","0045926 // negative regulation of growth // inferred from sequence or structural similarity /// 0071276 // cellular response to cadmium ion // inferred from expression pattern /// 0071294 // cellular response to zinc ion // inferred from sequence or structural similarity","0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity","0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation","---","---"
"210764_s_at",-1.40415035,-1.181229307,-1.837596179,"DOWN","AF003114","chr1:86047195-86048928 (+) // 92.87 // p22.3","cysteine-rich, angiogenic inducer, 61","CYR61","ENSG00000142871 /// OTTHUMG00000010577","3491","602369","NP_001545","NM_001554","0001558 // regulation of cell growth // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0002041 // intussusceptive angiogenesis // inferred from electronic annotation /// 0003181 // atrioventricular valve morphogenesis // inferred from electronic annotation /// 0003278 // apoptotic process involved in heart morphogenesis // inferred from electronic annotation /// 0003281 // ventricular septum development // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0010518 // positive regulation of phospholipase activity // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030513 // positive regulation of BMP signaling pathway // inferred from genetic interaction /// 0033690 // positive regulation of osteoblast proliferation // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0044319 // wound healing, spreading of cells // inferred from direct assay /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060413 // atrial septum morphogenesis // inferred from electronic annotation /// 0060591 // chondroblast differentiation // inferred from electronic annotation /// 0060710 // chorio-allantoic fusion // inferred from electronic annotation /// 0060716 // labyrinthine layer blood vessel development // inferred from electronic annotation /// 0061036 // positive regulation of cartilage development // inferred from electronic annotation /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0072593 // reactive oxygen species metabolic process // inferred from electronic annotation /// 2000304 // positive regulation of ceramide biosynthetic process // inferred from electronic annotation","0005576 // extracellular region // inferred from electronic annotation","0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // inferred from electronic annotation","Hypertrophy_model // GenMAPP","IPR000867 // Insulin-like growth factor-binding protein, IGFBP // 2.5E-15 /// IPR000884 // Thrombospondin, type 1 repeat // 2.6E-12 /// IPR001007 // von Willebrand factor, type C // 1.3E-13 /// IPR006208 // Glycoprotein hormone subunit beta, cystine knot // 5.4E-20"
"210951_x_at",1.491184399,1.286601497,1.13055817,"UP","AF125393","chr15:55497424-55562484 (-) // 91.61 // q21.3","RAB27A, member RAS oncogene family","RAB27A","ENSG00000069974 /// OTTHUMG00000131959","5873","603868 /// 607624","NP_004571 /// NP_899057 /// NP_899058 /// NP_899059 /// XP_005254633 /// XP_005254634","NM_004580 /// NM_183234 /// NM_183235 /// NM_183236 /// XM_005254576 /// XM_005254577","0006184 // GTP catabolic process // inferred from electronic annotation /// 0006605 // protein targeting // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from mutant phenotype /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0032400 // melanosome localization // inferred from electronic annotation /// 0032402 // melanosome transport // inferred from electronic annotation /// 0043316 // cytotoxic T cell degranulation // inferred from electronic annotation /// 0043320 // natural killer cell degranulation // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045921 // positive regulation of exocytosis // inferred from mutant phenotype /// 0051875 // pigment granule localization // inferred from electronic annotation /// 0051904 // pigment granule transport // inferred from electronic annotation /// 0071985 // multivesicular body sorting pathway // inferred from mutant phenotype","0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0030425 // dendrite // inferred from direct assay /// 0030667 // secretory granule membrane // inferred from electronic annotation /// 0032585 // multivesicular body membrane // inferred from direct assay /// 0042470 // melanosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070382 // exocytic vesicle // inferred from direct assay","0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0005525 // GTP binding // inferred from sequence or structural similarity /// 0019003 // GDP binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031489 // myosin V binding // inferred from electronic annotation","---","IPR000795 // Elongation factor, GTP-binding domain // 2.4E-9 /// IPR001806 // Small GTPase superfamily // 8.3E-60 /// IPR006689 // Small GTPase superfamily, ARF/SAR type // 7.1E-15 /// IPR013684 // Mitochondrial Rho-like // 9.8E-20"
"211276_at",-3.192937403,-1.691676985,-3.121707953,"DOWN","AF063606","chrX:101380709-101382683 (+) // 59.85 // q22.1","transcription elongation factor A (SII)-like 2","TCEAL2","ENSG00000184905 /// OTTHUMG00000022048","140597","---","NP_525129 /// XP_006724684","NM_080390 /// XM_006724621","0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation","0005634 // nucleus // inferred from electronic annotation","---","---","IPR021156 // Transcription elongation factor A-like/Brain expressed X-linked-like // 2.5E-24"
"211343_s_at",2.901058641,1.89492706,1.83294497,"UP","M33653","chr10:71689796-71718771 (+) // 90.72 // q22.1","collagen, type XIII, alpha 1","COL13A1","ENSG00000197467 /// OTTHUMG00000018394","1305","120350","NP_001123575 /// NP_542988 /// NP_542990 /// NP_542991 /// NP_542992 /// NP_542995 /// XP_006717695","NM_001130103 /// NM_005203 /// NM_080798 /// NM_080799 /// NM_080800 /// NM_080801 /// NM_080802 /// NM_080803 /// NM_080804 /// NM_080805 /// NM_080806 /// NM_080807 /// NM_080808 /// NM_080809 /// NM_080810 /// NM_080811 /// NM_080812 /// NM_080813 /// NM_080814 /// NM_080815 /// XM_006717632","0001503 // ossification // inferred from electronic annotation /// 0001763 // morphogenesis of a branching structure // inferred from sequence or structural similarity /// 0001958 // endochondral ossification // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from physical interaction /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from expression pattern /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement","0005576 // extracellular region // traceable author statement /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005600 // collagen type XIII trimer // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from direct assay","---","IPR008160 // Collagen triple helix repeat // 1.3E-14 /// IPR008160 // Collagen triple helix repeat // 1.3E-12 /// IPR008160 // Collagen triple helix repeat // 1.4E-12 /// IPR008160 // Collagen triple helix repeat // 4.3E-11 /// IPR008160 // Collagen triple helix repeat // 5.4E-13 /// IPR008160 // Collagen triple helix repeat // 3.5E-14 /// IPR008160 // Collagen triple helix repeat // 3.1E-14 /// IPR008160 // Collagen triple helix repeat // 1.7E-13 /// IPR008160 // Collagen triple helix repeat // 2.7E-10 /// IPR008160 // Collagen triple helix repeat // 4.0E-13 /// IPR008160 // Collagen triple helix repeat // 1.2E-14 /// IPR008160 // Collagen triple helix repeat // 2.1E-13 /// IPR008160 // Collagen triple helix repeat // 9.1E-12 /// IPR008160 // Collagen triple helix repeat // 5.2E-13 /// IPR008160 // Collagen triple helix repeat // 3.4E-14 /// IPR008160 // Collagen triple helix repeat // 3.0E-14 /// IPR008160 // Collagen triple helix repeat // 1.6E-13 /// IPR008160 // Collagen triple helix repeat // 2.6E-10 /// IPR008160 // Collagen triple helix repeat // 3.9E-13 /// IPR008160 // Collagen triple helix repeat // 1.3E-13 /// IPR008160 // Collagen triple helix repeat // 9.7E-12 /// IPR008160 // Collagen triple helix repeat // 2.0E-14 /// IPR008160 // Collagen triple helix repeat // 2.6E-14 /// IPR008160 // Collagen triple helix repeat // 1.8E-14 /// IPR008160 // Collagen triple helix repeat // 3.4E-10 /// IPR008160 // Collagen triple helix repeat // 1.5E-14 /// IPR008160 // Collagen triple helix repeat // 2.1E-10 /// IPR008160 // Collagen triple helix repeat // 9.0E-14"
"211429_s_at",3.23984663,3.879461024,3.304456113,"UP","AF119873","chr15:66068531-66069687 (+) // 50.83 // q22.31","serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1","SERPINA1","ENSG00000197249 /// OTTHUMG00000150355","5265","107400 /// 606963 /// 613490","NP_000286 /// NP_001002235 /// NP_001002236 /// NP_001121172 /// NP_001121173 /// NP_001121174 /// NP_001121175 /// NP_001121176 /// NP_001121177 /// NP_001121178 /// NP_001121179","NM_000295 /// NM_001002235 /// NM_001002236 /// NM_001127700 /// NM_001127701 /// NM_001127702 /// NM_001127703 /// NM_001127704 /// NM_001127705 /// NM_001127706 /// NM_001127707","0001666 // response to hypoxia // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030162 // regulation of proteolysis // not recorded /// 0030168 // platelet activation // traceable author statement /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033986 // response to methanol // inferred from electronic annotation /// 0034014 // response to triglyceride // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0046687 // response to chromate // inferred from electronic annotation","0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from mutant phenotype /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0001948 // glycoprotein binding // inferred from physical interaction /// 0002020 // protease binding // inferred from physical interaction /// 0004866 // endopeptidase inhibitor activity // inferred from electronic annotation /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0004867 // serine-type endopeptidase inhibitor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction","---","IPR023796 // Serpin domain // 4.7E-122 /// IPR023796 // Serpin domain // 6.8E-82"
"211478_s_at",3.517230456,3.472696237,2.046778157,"UP","M74777","chr2:162849284-162930498 (-) // 96.24 // q24.2","dipeptidyl-peptidase 4","DPP4","ENSG00000197635 /// OTTHUMG00000132056","1803","102720","NP_001926 /// XP_005246428","NM_001935 /// XM_005246371","0001666 // response to hypoxia // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010716 // negative regulation of extracellular matrix disassembly // inferred from direct assay /// 0031295 // T cell costimulation // inferred from direct assay /// 0033632 // regulation of cell-cell adhesion mediated by integrin // inferred from direct assay /// 0042110 // T cell activation // inferred from direct assay /// 0043542 // endothelial cell migration // inferred from direct assay","0005576 // extracellular region // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0046581 // intercellular canaliculus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071438 // invadopodium membrane // inferred from direct assay","0002020 // protease binding // inferred from physical interaction /// 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from direct assay /// 0008239 // dipeptidyl-peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction","---","IPR001375 // Peptidase S9, prolyl oligopeptidase, catalytic domain // 2.6E-61 /// IPR002469 // Peptidase S9B, dipeptidylpeptidase IV N-terminal // 6.8E-116"
"211564_s_at",2.295442673,3.40824858,2.372378147,"UP","BC003096","chr5:131593399-131608023 (+) // 96.81 // q31.1","PDZ and LIM domain 4","PDLIM4","ENSG00000131435 /// OTTHUMG00000059645","8572","166710 /// 603422","NP_001124499 /// NP_003678 /// XP_006714786","NM_001131027 /// NM_003687 /// XM_006714723","---","---","0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR001478 // PDZ domain // 1.8E-19 /// IPR001478 // PDZ domain // 5.2E-20 /// IPR001781 // Zinc finger, LIM-type // 6.3E-19"
"211596_s_at",-1.206501201,-1.351623112,-1.157120116,"DOWN","AB050468","chr3:66429221-66551351 (-) // 97.86 // p14.1","leucine-rich repeats and immunoglobulin-like domains 1","LRIG1","ENSG00000144749 /// OTTHUMG00000158727","26018","608868","NP_056356","NM_015541","---","0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0005515 // protein binding // inferred from electronic annotation","---","IPR000483 // Cysteine-rich flanking region, C-terminal // 2.5E-7 /// IPR000483 // Cysteine-rich flanking region, C-terminal // 2.5E-7 /// IPR001611 // Leucine-rich repeat // 4.4E-4 /// IPR001611 // Leucine-rich repeat // 2.0E-4 /// IPR001611 // Leucine-rich repeat // 4.3E-4 /// IPR001611 // Leucine-rich repeat // 1.9E-4 /// IPR013098 // Immunoglobulin I-set // 3.1E-13 /// IPR013098 // Immunoglobulin I-set // 1.1E-23 /// IPR013098 // Immunoglobulin I-set // 1.4E-23 /// IPR013098 // Immunoglobulin I-set // 3.0E-13 /// IPR013098 // Immunoglobulin I-set // 5.9E-10 /// IPR013098 // Immunoglobulin I-set // 1.4E-23 /// IPR013106 // Immunoglobulin V-set domain // 3.5E-8 /// IPR013106 // Immunoglobulin V-set domain // 2.1E-9 /// IPR013106 // Immunoglobulin V-set domain // 3.4E-8 /// IPR013106 // Immunoglobulin V-set domain // 1.6E-9 /// IPR013151 // Immunoglobulin // 2.6E-8 /// IPR013151 // Immunoglobulin // 3.1E-11 /// IPR013151 // Immunoglobulin // 2.5E-8 /// IPR013151 // Immunoglobulin // 3.1E-11"
"211653_x_at",-1.676708937,-1.244951361,-1.436684264,"DOWN","M33376","chr10:5008103-5260786 (+) // 94.44 // p15.1 /// chr10:5032124-5045968 (-) // 97.47 // p15.1","aldo-keto reductase family 1, member C2 /// aldo-keto reductase family 1 member C2-like","AKR1C2 /// LOC101930400","ENSG00000151632 /// OTTHUMG00000017584","1646 /// 101930400","600450 /// 614279","NP_001128713 /// NP_001345 /// NP_995317 /// XP_005276151","NM_001135241 /// NM_001354 /// NM_205845 /// XM_005276094","0001523 // retinoid metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007586 // digestion // inferred from direct assay /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // inferred from direct assay /// 0008206 // bile acid metabolic process // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0015721 // bile acid and bile salt transport // traceable author statement /// 0030299 // intestinal cholesterol absorption // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0034694 // response to prostaglandin // inferred from direct assay /// 0042448 // progesterone metabolic process // inferred from direct assay /// 0042574 // retinal metabolic process // inferred from direct assay /// 0042632 // cholesterol homeostasis // traceable author statement /// 0044597 // daunorubicin metabolic process // inferred from mutant phenotype /// 0044598 // doxorubicin metabolic process // inferred from mutant phenotype /// 0046683 // response to organophosphorus // inferred from expression pattern /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0071395 // cellular response to jasmonic acid stimulus // inferred from direct assay","0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0004032 // alditol:NADP+ 1-oxidoreductase activity // inferred from direct assay /// 0004033 // aldo-keto reductase (NADP) activity // traceable author statement /// 0004958 // prostaglandin F receptor activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016655 // oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor // inferred from direct assay /// 0018636 // phenanthrene 9,10-monooxygenase activity // inferred from direct assay /// 0031406 // carboxylic acid binding // inferred from direct assay /// 0032052 // bile acid binding // inferred from direct assay /// 0047006 // 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity // inferred from electronic annotation /// 0047042 // androsterone dehydrogenase (B-specific) activity // inferred from direct assay /// 0047086 // ketosteroid monooxygenase activity // inferred from direct assay /// 0047115 // trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity // inferred from direct assay /// 0047718 // indanol dehydrogenase activity // inferred from electronic annotation","---","IPR023210 // NADP-dependent oxidoreductase domain // 6.9E-65 /// IPR023210 // NADP-dependent oxidoreductase domain // 5.0E-61"
"211657_at",1.76084323,1.356359538,1.696450852,"UP","M18728","chr19:42259496-42275777 (+) // 47.65 // q13.2","carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)","CEACAM6","ENSG00000086548 /// OTTHUMG00000151064","4680","163980","NP_002474","NM_002483","0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement","0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation","0005515 // protein binding // inferred from physical interaction","---","IPR013098 // Immunoglobulin I-set // 6.4E-11 /// IPR013098 // Immunoglobulin I-set // 1.5E-11 /// IPR013106 // Immunoglobulin V-set domain // 2.3E-25 /// IPR013151 // Immunoglobulin // 3.6E-9 /// IPR013151 // Immunoglobulin // 9.4E-12"
"211696_x_at",-1.449215162,-1.394881343,-1.770054507,"DOWN","AF349114","chr11:5246725-5248286 (-) // 99.48 // p15.4","hemoglobin, beta","HBB","ENSG00000244734 /// OTTHUMG00000066678","3043","140700 /// 141749 /// 141900 /// 603902 /// 603903 /// 604131 /// 611162 /// 613985","NP_000509","NM_000518","0006810 // transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0015671 // oxygen transport // non-traceable author statement /// 0015671 // oxygen transport // traceable author statement /// 0015701 // bicarbonate transport // traceable author statement /// 0030185 // nitric oxide transport // non-traceable author statement /// 0042542 // response to hydrogen peroxide // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // non-traceable author statement /// 0050880 // regulation of blood vessel size // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0070293 // renal absorption // inferred from mutant phenotype","0005576 // extracellular region // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005833 // hemoglobin complex // inferred from direct assay /// 0005833 // hemoglobin complex // non-traceable author statement /// 0005833 // hemoglobin complex // traceable author statement /// 0031838 // haptoglobin-hemoglobin complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay","0004601 // peroxidase activity // inferred from direct assay /// 0005344 // oxygen transporter activity // non-traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019825 // oxygen binding // inferred from direct assay /// 0020037 // heme binding // inferred from electronic annotation /// 0030492 // hemoglobin binding // inferred from direct assay /// 0031720 // haptoglobin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000971 // Globin // 3.5E-33"
"211699_x_at",-1.37754271,-1.713763269,-1.834739709,"DOWN","AF349571","chr16:226690-227447 (+) // 99.59 // p13.3 /// chr16:222886-223613 (+) // 95.11 // p13.3","hemoglobin, alpha 1 /// hemoglobin, alpha 2","HBA1 /// HBA2","ENSG00000188536 /// ENSG00000206172 /// OTTHUMG00000059924 /// OTTHUMG00000060138","3039 /// 3040","140700 /// 141800 /// 141850 /// 604131 /// 613978","NP_000508 /// NP_000549","NM_000517 /// NM_000558","0006810 // transport // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0015671 // oxygen transport // traceable author statement /// 0015701 // bicarbonate transport // traceable author statement /// 0042542 // response to hydrogen peroxide // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay","0005576 // extracellular region // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005833 // hemoglobin complex // inferred from direct assay /// 0005833 // hemoglobin complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0031838 // haptoglobin-hemoglobin complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay","0004601 // peroxidase activity // inferred from direct assay /// 0005344 // oxygen transporter activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019825 // oxygen binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0031720 // haptoglobin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000971 // Globin // 2.9E-32"
"211719_x_at",2.971956894,2.443061062,2.735510003,"UP","BC005858","chr2:216225586-216235072 (-) // 94.05 // q35","fibronectin 1","FN1","ENSG00000115414 /// OTTHUMG00000133054","2335","135600 /// 601894 /// 614101","NP_002017 /// NP_473375 /// NP_997639 /// NP_997641 /// NP_997643 /// NP_997647 /// XP_005246454 /// XP_005246455 /// XP_005246456 /// XP_005246457 /// XP_005246458 /// XP_005246459 /// XP_005246460 /// XP_005246461 /// XP_005246462 /// XP_005246463 /// XP_005246464 /// XP_005246465 /// XP_005246466 /// XP_005246467 /// XP_005246468 /// XP_005246469 /// XP_005246470 /// XP_005246471 /// XP_005246472 /// XP_005246473 /// XP_005246474","NM_002026 /// NM_054034 /// NM_212474 /// NM_212475 /// NM_212476 /// NM_212478 /// NM_212482 /// XM_005246397 /// XM_005246398 /// XM_005246399 /// XM_005246400 /// XM_005246401 /// XM_005246402 /// XM_005246403 /// XM_005246404 /// XM_005246405 /// XM_005246406 /// XM_005246407 /// XM_005246408 /// XM_005246409 /// XM_005246410 /// XM_005246411 /// XM_005246412 /// XM_005246413 /// XM_005246414 /// XM_005246415 /// XM_005246416 /// XM_005246417","0001525 // angiogenesis // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007044 // cell-substrate junction assembly // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007161 // calcium-independent cell-matrix adhesion // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009611 // response to wounding // non-traceable author statement /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0016477 // cell migration // non-traceable author statement /// 0018149 // peptide cross-linking // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0042060 // wound healing // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement","0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay","0002020 // protease binding // inferred from physical interaction /// 0005178 // integrin binding // inferred from direct assay /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // non-traceable author statement /// 0008201 // heparin binding // non-traceable author statement /// 0016504 // peptidase activator activity // inferred from electronic annotation","Inflammatory_Response_Pathway // GenMAPP","IPR000083 // Fibronectin, type I // 2.0E-14 /// IPR000083 // Fibronectin, type I // 2.7E-18 /// IPR000083 // Fibronectin, type I // 1.6E-16 /// IPR000083 // Fibronectin, type I // 1.2E-18 /// IPR000083 // Fibronectin, type I // 3.5E-18 /// IPR000083 // Fibronectin, type I // 1.8E-12 /// IPR000083 // Fibronectin, type I // 1.5E-18 /// IPR000083 // Fibronectin, type I // 4.0E-16 /// IPR000083 // Fibronectin, type I // 5.3E-18 /// IPR000083 // Fibronectin, type I // 1.2E-18 /// IPR000083 // Fibronectin, type I // 8.3E-17 /// IPR000083 // Fibronectin, type I // 1.5E-13 /// IPR000083 // Fibronectin, type I // 2.2E-14 /// IPR000083 // Fibronectin, type I // 3.0E-18 /// IPR000083 // Fibronectin, type I // 1.8E-16 /// IPR000083 // Fibronectin, type I // 1.3E-18 /// IPR000083 // Fibronectin, type I // 3.9E-18 /// IPR000083 // Fibronectin, type I // 2.0E-12 /// IPR000083 // Fibronectin, type I // 1.6E-18 /// IPR000083 // Fibronectin, type I // 4.4E-16 /// IPR000083 // Fibronectin, type I // 5.9E-18 /// IPR000083 // Fibronectin, type I // 1.3E-18 /// IPR000083 // Fibronectin, type I // 9.2E-17 /// IPR000083 // Fibronectin, type I // 1.7E-13 /// IPR000083 // Fibronectin, type I // 2.1E-14 /// IPR000083 // Fibronectin, type I // 2.9E-18 /// IPR000083 // Fibronectin, type I // 1.7E-16 /// IPR000083 // Fibronectin, type I // 3.7E-18 /// IPR000083 // Fibronectin, type I // 4.3E-16 /// IPR000083 // Fibronectin, type I // 5.6E-18 /// IPR000083 // Fibronectin, type I // 1.3E-18 /// IPR000083 // Fibronectin, type I // 8.8E-17 /// IPR000083 // Fibronectin, type I // 1.6E-13 /// IPR000083 // Fibronectin, type I // 1.9E-14 /// IPR000083 // Fibronectin, type I // 2.6E-18 /// IPR000083 // Fibronectin, type I // 3.4E-18 /// IPR000083 // Fibronectin, type I // 1.4E-18 /// IPR000083 // Fibronectin, type I // 3.9E-16 /// IPR000083 // Fibronectin, type I // 5.2E-18 /// IPR000083 // Fibronectin, type I // 1.2E-18 /// IPR000083 // Fibronectin, type I // 8.1E-17 /// IPR000083 // Fibronectin, type I // 1.5E-13 /// IPR000083 // Fibronectin, type I // 1.4E-18 /// IPR000083 // Fibronectin, type I // 2.1E-12 /// IPR000083 // Fibronectin, type I // 1.7E-18 /// IPR000083 // Fibronectin, type I // 4.5E-16 /// IPR000083 // Fibronectin, type I // 1.4E-18 /// IPR000083 // Fibronectin, type I // 9.3E-17 /// IPR000083 // Fibronectin, type I // 1.7E-13 /// IPR000083 // Fibronectin, type I // 2.8E-18 /// IPR000083 // Fibronectin, type I // 1.9E-12 /// IPR000083 // Fibronectin, type I // 4.2E-16 /// IPR000083 // Fibronectin, type I // 1.3E-18 /// IPR000083 // Fibronectin, type I // 8.7E-17 /// IPR000083 // Fibronectin, type I // 1.6E-13 /// IPR000083 // Fibronectin, type I // 3.6E-18 /// IPR000083 // Fibronectin, type I // 4.1E-16 /// IPR000083 // Fibronectin, type I // 5.4E-18 /// IPR000083 // Fibronectin, type I // 1.2E-18 /// IPR000083 // Fibronectin, type I // 8.4E-17 /// IPR000083 // Fibronectin, type I // 1.5E-13 /// IPR000083 // Fibronectin, type I // 1.2E-18 /// IPR000083 // Fibronectin, type I // 8.4E-17 /// IPR000083 // Fibronectin, type I // 1.5E-13 /// IPR000083 // Fibronectin, type I // 5.5E-18 /// IPR000083 // Fibronectin, type I // 1.3E-18 /// IPR000083 // Fibronectin, type I // 8.6E-17 /// IPR000083 // Fibronectin, type I // 1.5E-13 /// IPR000083 // Fibronectin, type I // 3.8E-18 /// IPR000083 // Fibronectin, type I // 5.7E-18 /// IPR000083 // Fibronectin, type I // 1.3E-18 /// IPR000083 // Fibronectin, type I // 8.9E-17 /// IPR000083 // Fibronectin, type I // 1.6E-13 /// IPR000562 // Fibronectin, type II, collagen-binding // 1.1E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 6.5E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 1.2E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 7.2E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 6.9E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 6.3E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 7.3E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 6.8E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 6.6E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 6.7E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 7.0E-21 /// IPR003961 // Fibronectin, type III // 2.3E-15 /// IPR003961 // Fibronectin, type III // 5.2E-16 /// IPR003961 // Fibronectin, type III // 8.3E-22 /// IPR003961 // Fibronectin, type III // 2.1E-18 /// IPR003961 // Fibronectin, type III // 6.6E-19 /// IPR003961 // Fibronectin, type III // 6.0E-10 /// IPR003961 // Fibronectin, type III // 1.3E-16 /// IPR003961 // Fibronectin, type III // 3.7E-20 /// IPR003961 // Fibronectin, type III // 6.0E-20 /// IPR003961 // Fibronectin, type III // 4.9E-24 /// IPR003961 // Fibronectin, type III // 1.0E-20 /// IPR003961 // Fibronectin, type III // 1.1E-19 /// IPR003961 // Fibronectin, type III // 1.3E-18 /// IPR003961 // Fibronectin, type III // 4.0E-21 /// IPR003961 // Fibronectin, type III // 5.8E-11 /// IPR003961 // Fibronectin, type III // 2.5E-15 /// IPR003961 // Fibronectin, type III // 5.7E-16 /// IPR003961 // Fibronectin, type III // 9.1E-22 /// IPR003961 // Fibronectin, type III // 2.4E-18 /// IPR003961 // Fibronectin, type III // 7.3E-19 /// IPR003961 // Fibronectin, type III // 6.6E-10 /// IPR003961 // Fibronectin, type III // 1.4E-16 /// IPR003961 // Fibronectin, type III // 8.1E-16 /// IPR003961 // Fibronectin, type III // 4.1E-20 /// IPR003961 // Fibronectin, type III // 6.6E-20 /// IPR003961 // Fibronectin, type III // 5.4E-24 /// IPR003961 // Fibronectin, type III // 1.1E-20 /// IPR003961 // Fibronectin, type III // 1.1E-15 /// IPR003961 // Fibronectin, type III // 1.3E-19 /// IPR003961 // Fibronectin, type III // 1.4E-18 /// IPR003961 // Fibronectin, type III // 4.4E-21 /// IPR003961 // Fibronectin, type III // 6.4E-11 /// IPR003961 // Fibronectin, type III // 2.4E-15 /// IPR003961 // Fibronectin, type III // 5.5E-16 /// IPR003961 // Fibronectin, type III // 8.7E-22 /// IPR003961 // Fibronectin, type III // 2.3E-18 /// IPR003961 // Fibronectin, type III // 7.0E-19 /// IPR003961 // Fibronectin, type III // 6.3E-10 /// IPR003961 // Fibronectin, type III // 3.9E-20 /// IPR003961 // Fibronectin, type III // 6.4E-20 /// IPR003961 // Fibronectin, type III // 5.2E-24 /// IPR003961 // Fibronectin, type III // 1.1E-20 /// IPR003961 // Fibronectin, type III // 1.1E-15 /// IPR003961 // Fibronectin, type III // 1.2E-19 /// IPR003961 // Fibronectin, type III // 1.3E-18 /// IPR003961 // Fibronectin, type III // 4.2E-21 /// IPR003961 // Fibronectin, type III // 6.1E-11 /// IPR003961 // Fibronectin, type III // 2.2E-15 /// IPR003961 // Fibronectin, type III // 5.0E-16 /// IPR003961 // Fibronectin, type III // 8.0E-22 /// IPR003961 // Fibronectin, type III // 6.4E-19 /// IPR003961 // Fibronectin, type III // 5.8E-10 /// IPR003961 // Fibronectin, type III // 1.2E-16 /// IPR003961 // Fibronectin, type III // 3.6E-20 /// IPR003961 // Fibronectin, type III // 5.8E-20 /// IPR003961 // Fibronectin, type III // 4.7E-24 /// IPR003961 // Fibronectin, type III // 9.9E-21 /// IPR003961 // Fibronectin, type III // 1.2E-18 /// IPR003961 // Fibronectin, type III // 3.9E-21 /// IPR003961 // Fibronectin, type III // 8.4E-11 /// IPR003961 // Fibronectin, type III // 2.6E-15 /// IPR003961 // Fibronectin, type III // 5.8E-16 /// IPR003961 // Fibronectin, type III // 9.3E-22 /// IPR003961 // Fibronectin, type III // 7.4E-19 /// IPR003961 // Fibronectin, type III // 6.7E-10 /// IPR003961 // Fibronectin, type III // 8.3E-16 /// IPR003961 // Fibronectin, type III // 6.7E-20 /// IPR003961 // Fibronectin, type III // 5.5E-24 /// IPR003961 // Fibronectin, type III // 1.2E-20 /// IPR003961 // Fibronectin, type III // 1.2E-15 /// IPR003961 // Fibronectin, type III // 4.5E-21 /// IPR003961 // Fibronectin, type III // 9.0E-11 /// IPR003961 // Fibronectin, type III // 5.4E-16 /// IPR003961 // Fibronectin, type III // 8.6E-22 /// IPR003961 // Fibronectin, type III // 2.2E-18 /// IPR003961 // Fibronectin, type III // 6.9E-19 /// IPR003961 // Fibronectin, type III // 6.2E-10 /// IPR003961 // Fibronectin, type III // 6.3E-20 /// IPR003961 // Fibronectin, type III // 5.1E-24 /// IPR003961 // Fibronectin, type III // 6.0E-11 /// IPR003961 // Fibronectin, type III // 5.3E-16 /// IPR003961 // Fibronectin, type III // 8.4E-22 /// IPR003961 // Fibronectin, type III // 6.7E-19 /// IPR003961 // Fibronectin, type III // 6.1E-10 /// IPR003961 // Fibronectin, type III // 6.1E-20 /// IPR003961 // Fibronectin, type III // 1.2E-19 /// IPR003961 // Fibronectin, type III // 5.8E-11 /// IPR003961 // Fibronectin, type III // 7.5E-16 /// IPR003961 // Fibronectin, type III // 3.7E-20 /// IPR003961 // Fibronectin, type III // 6.1E-20 /// IPR003961 // Fibronectin, type III // 4.9E-24 /// IPR003961 // Fibronectin, type III // 1.0E-20 /// IPR003961 // Fibronectin, type III // 1.2E-19 /// IPR003961 // Fibronectin, type III // 1.3E-18 /// IPR003961 // Fibronectin, type III // 4.0E-21 /// IPR003961 // Fibronectin, type III // 8.8E-11 /// IPR003961 // Fibronectin, type III // 8.5E-22 /// IPR003961 // Fibronectin, type III // 6.8E-19 /// IPR003961 // Fibronectin, type III // 3.8E-20 /// IPR003961 // Fibronectin, type III // 6.2E-20 /// IPR003961 // Fibronectin, type III // 5.0E-24 /// IPR003961 // Fibronectin, type III // 4.1E-21 /// IPR003961 // Fibronectin, type III // 8.3E-11 /// IPR003961 // Fibronectin, type III // 5.6E-16 /// IPR003961 // Fibronectin, type III // 8.9E-22 /// IPR003961 // Fibronectin, type III // 7.1E-19 /// IPR003961 // Fibronectin, type III // 6.4E-10 /// IPR003961 // Fibronectin, type III // 4.0E-20 /// IPR003961 // Fibronectin, type III // 6.5E-20 /// IPR003961 // Fibronectin, type III // 1.4E-18 /// IPR003961 // Fibronectin, type III // 4.3E-21 /// IPR003961 // Fibronectin, type III // 8.7E-11"
"211725_s_at",1.760542677,1.588660432,1.440118809,"UP","BC005884","chr1:8921063-8926551 (+) // 54.1 // p36.23","BH3 interacting domain death agonist","BID","ENSG00000015475 /// OTTHUMG00000150087","637","601997","NP_001187 /// NP_001231496 /// NP_001231498 /// NP_001231499 /// NP_001231501 /// NP_932070 /// NP_932071","NM_001196 /// NM_001244567 /// NM_001244569 /// NM_001244570 /// NM_001244572 /// NM_197966 /// NM_197967","0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001836 // release of cytochrome c from mitochondria // inferred from direct assay /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006006 // glucose metabolic process // traceable author statement /// 0006094 // gluconeogenesis // traceable author statement /// 0006096 // glycolytic process // inferred from electronic annotation /// 0006096 // glycolytic process // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // traceable author statement /// 0008637 // apoptotic mitochondrial changes // traceable author statement /// 0009615 // response to virus // inferred from expression pattern /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032461 // positive regulation of protein oligomerization // inferred from direct assay /// 0032464 // positive regulation of protein homooligomerization // inferred from direct assay /// 0034349 // glial cell apoptotic process // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042770 // signal transduction in response to DNA damage // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0044281 // small molecule metabolic process // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0046902 // regulation of mitochondrial membrane permeability // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051402 // neuron apoptotic process // traceable author statement /// 0090150 // establishment of protein localization to membrane // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from genetic interaction /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from mutant phenotype /// 0097191 // extrinsic apoptotic signaling pathway // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 1901030 // positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway // traceable author statement /// 1902108 // regulation of mitochondrial membrane permeability involved in apoptotic process // inferred from electronic annotation /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // traceable author statement","0000015 // phosphopyruvate hydratase complex // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031305 // integral component of mitochondrial inner membrane // inferred from electronic annotation /// 0031430 // M band // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0032592 // integral component of mitochondrial membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0000287 // magnesium ion binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0004634 // phosphopyruvate hydratase activity // inferred from electronic annotation /// 0004634 // phosphopyruvate hydratase activity // traceable author statement /// 0005123 // death receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016829 // lyase activity // inferred from electronic annotation /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation","Apoptosis // GenMAPP /// Apoptosis_GenMAPP // GenMAPP /// Glycolysis_and_Gluconeogenesis // GenMAPP","IPR010479 // BH3 interacting // 7.4E-98 /// IPR010479 // BH3 interacting // 3.3E-98 /// IPR010479 // BH3 interacting // 3.0E-51 /// IPR010479 // BH3 interacting // 1.0E-30"
"211745_x_at",-1.384066794,-1.614379723,-1.565200929,"DOWN","BC005931","chr16:226678-227521 (+) // 91.15 // p13.3","hemoglobin, alpha 1 /// hemoglobin, alpha 2","HBA1 /// HBA2","ENSG00000188536 /// ENSG00000206172 /// OTTHUMG00000059924 /// OTTHUMG00000060138","3039 /// 3040","140700 /// 141800 /// 141850 /// 604131 /// 613978","NP_000508 /// NP_000549","NM_000517 /// NM_000558","0006810 // transport // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0015671 // oxygen transport // traceable author statement /// 0015701 // bicarbonate transport // traceable author statement /// 0042542 // response to hydrogen peroxide // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay","0005576 // extracellular region // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005833 // hemoglobin complex // inferred from direct assay /// 0005833 // hemoglobin complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0031838 // haptoglobin-hemoglobin complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay","0004601 // peroxidase activity // inferred from direct assay /// 0005344 // oxygen transporter activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019825 // oxygen binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0031720 // haptoglobin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000971 // Globin // 2.9E-32"
"212224_at",-2.084916156,-1.843646788,-1.331514003,"DOWN","NM_000689","chr9:75515586-75567971 (-) // 97.58 // q21.13","aldehyde dehydrogenase 1 family, member A1","ALDH1A1","ENSG00000165092 /// OTTHUMG00000020019","216","100640","NP_000680","NM_000689","0006069 // ethanol oxidation // traceable author statement /// 0006081 // cellular aldehyde metabolic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008218 // bioluminescence // inferred from electronic annotation /// 0032320 // positive regulation of Ras GTPase activity // traceable author statement /// 0042572 // retinol metabolic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation","0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0001758 // retinal dehydrogenase activity // inferred from electronic annotation /// 0003995 // acyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0004029 // aldehyde dehydrogenase (NAD) activity // not recorded /// 0005099 // Ras GTPase activator activity // traceable author statement /// 0005497 // androgen binding // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation","4AMINOBUTMETAB-PWY // HumanCyc /// NPGLUCAT-PWY // HumanCyc /// YEAST-4AMINOBUTMETAB-PWY // HumanCyc","IPR008670 // Acyl-CoA reductase, LuxC // 3.1E-9 /// IPR015590 // Aldehyde dehydrogenase domain // 1.1E-191"
"212236_x_at",1.013656585,1.373103065,1.153505663,"UP","Z19574","chr17:39775693-39780806 (-) // 93.83 // q21.2","junction plakoglobin /// keratin 17","JUP /// KRT17","ENSG00000128422 /// ENSG00000173801 /// OTTHUMG00000133505","3728 /// 3872","148069 /// 167210 /// 173325 /// 184500 /// 601214 /// 611528","NP_000413 /// NP_002221 /// NP_068831 /// XP_005257370 /// XP_005257406 /// XP_006721934 /// XP_006721935 /// XP_006721936 /// XP_006721937 /// XP_006721938 /// XP_006721939 /// XP_006721940 /// XP_006721941","NM_000422 /// NM_002230 /// NM_021991 /// XM_005257313 /// XM_005257349 /// XM_006721871 /// XM_006721872 /// XM_006721873 /// XM_006721874 /// XM_006721875 /// XM_006721876 /// XM_006721877 /// XM_006721878","0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0000902 // cell morphogenesis // not recorded /// 0002009 // morphogenesis of an epithelium // inferred from electronic annotation /// 0002159 // desmosome assembly // inferred from direct assay /// 0002159 // desmosome assembly // inferred from mutant phenotype /// 0003136 // negative regulation of heart induction by canonical Wnt signaling pathway // not recorded /// 0003181 // atrioventricular valve morphogenesis // not recorded /// 0003308 // negative regulation of Wnt signaling pathway involved in heart development // not recorded /// 0007016 // cytoskeletal anchoring at plasma membrane // not recorded /// 0007016 // cytoskeletal anchoring at plasma membrane // non-traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0007369 // gastrulation // not recorded /// 0007398 // ectoderm development // not recorded /// 0007399 // nervous system development // not recorded /// 0008544 // epidermis development // traceable author statement /// 0016331 // morphogenesis of embryonic epithelium // not recorded /// 0016337 // single organismal cell-cell adhesion // inferred from direct assay /// 0016337 // single organismal cell-cell adhesion // inferred from mutant phenotype /// 0016477 // cell migration // inferred from mutant phenotype /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0031424 // keratinization // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from direct assay /// 0042307 // positive regulation of protein import into nucleus // inferred from direct assay /// 0043588 // skin development // not recorded /// 0045109 // intermediate filament organization // inferred from electronic annotation /// 0045216 // cell-cell junction organization // traceable author statement /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0048599 // oocyte development // not recorded /// 0050982 // detection of mechanical stimulus // inferred from direct assay /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051291 // protein heterooligomerization // inferred from electronic annotation /// 0051798 // positive regulation of hair follicle development // inferred from electronic annotation /// 0071603 // endothelial cell-cell adhesion // inferred from sequence or structural similarity /// 0071681 // cellular response to indole-3-methanol // inferred from direct assay /// 0086005 // ventricular cardiac muscle cell action potential // inferred from mutant phenotype /// 0086069 // bundle of His cell to Purkinje myocyte communication // inferred from mutant phenotype /// 0086091 // regulation of heart rate by cardiac conduction // inferred from mutant phenotype /// 0090002 // establishment of protein localization to plasma membrane // inferred from mutant phenotype /// 0090263 // positive regulation of canonical Wnt signaling pathway // inferred by curator","0005634 // nucleus // inferred from mutant phenotype /// 0005667 // transcription factor complex // not recorded /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from sequence or structural similarity /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005911 // cell-cell junction // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005915 // zonula adherens // not recorded /// 0005915 // zonula adherens // inferred from sequence or structural similarity /// 0005916 // fascia adherens // not recorded /// 0009898 // cytoplasmic side of plasma membrane // not recorded /// 0009898 // cytoplasmic side of plasma membrane // inferred from sequence or structural similarity /// 0014704 // intercalated disc // inferred from direct assay /// 0015629 // actin cytoskeleton // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // not recorded /// 0016327 // apicolateral plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0016342 // catenin complex // inferred from direct assay /// 0030018 // Z disc // not recorded /// 0030054 // cell junction // inferred from electronic annotation /// 0030056 // hemidesmosome // inferred from sequence or structural similarity /// 0030057 // desmosome // inferred from direct assay /// 0032993 // protein-DNA complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071665 // gamma-catenin-TCF7L2 complex // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation","0003713 // transcription coactivator activity // inferred from direct assay /// 0005198 // structural molecule activity // not recorded /// 0005198 // structural molecule activity // non-traceable author statement /// 0005199 // structural constituent of cell wall // inferred by curator /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // not recorded /// 0019903 // protein phosphatase binding // inferred from physical interaction /// 0032395 // MHC class II receptor activity // inferred from direct assay /// 0042289 // MHC class II protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0045294 // alpha-catenin binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from physical interaction","---","IPR000225 // Armadillo // 2.6E-11 /// IPR001664 // Intermediate filament protein // 2.7E-122 /// IPR001664 // Intermediate filament protein // 4.6E-94"
"212314_at",1.119211775,1.599232086,1.86525193,"UP","AB018289","chr4:25749051-25864345 (-) // 98.18 // p15.2","sel-1 suppressor of lin-12-like 3 (C. elegans)","SEL1L3","ENSG00000091490 /// OTTHUMG00000160331","23231","---","NP_056002 /// XP_005248200 /// XP_006714019 /// XP_006714020","NM_015187 /// XM_005248143 /// XM_006713956 /// XM_006713957","---","0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","---","---","IPR006597 // Sel1-like // 0.0014 /// IPR006597 // Sel1-like // 1.7E-7 /// IPR006597 // Sel1-like // 2.8E-7 /// IPR006597 // Sel1-like // 7.6E-4 /// IPR006597 // Sel1-like // 1.5E-8 /// IPR006597 // Sel1-like // 0.0047 /// IPR006597 // Sel1-like // 6.6E-4 /// IPR006597 // Sel1-like // 0.0014 /// IPR006597 // Sel1-like // 1.6E-7 /// IPR006597 // Sel1-like // 2.7E-7 /// IPR006597 // Sel1-like // 7.3E-4 /// IPR006597 // Sel1-like // 1.4E-8 /// IPR006597 // Sel1-like // 0.0046 /// IPR006597 // Sel1-like // 6.4E-4"
"212464_s_at",3.231877724,2.575288413,2.866277553,"UP","X02761","chr2:216225587-216300445 (-) // 98.88 // q35","fibronectin 1","FN1","ENSG00000115414 /// OTTHUMG00000133054","2335","135600 /// 601894 /// 614101","NP_002017 /// NP_473375 /// NP_997639 /// NP_997641 /// NP_997643 /// NP_997647 /// XP_005246454 /// XP_005246455 /// XP_005246456 /// XP_005246457 /// XP_005246458 /// XP_005246459 /// XP_005246460 /// XP_005246461 /// XP_005246462 /// XP_005246463 /// XP_005246464 /// XP_005246465 /// XP_005246466 /// XP_005246467 /// XP_005246468 /// XP_005246469 /// XP_005246470 /// XP_005246471 /// XP_005246472 /// XP_005246473 /// XP_005246474","NM_002026 /// NM_054034 /// NM_212474 /// NM_212475 /// NM_212476 /// NM_212478 /// NM_212482 /// XM_005246397 /// XM_005246398 /// XM_005246399 /// XM_005246400 /// XM_005246401 /// XM_005246402 /// XM_005246403 /// XM_005246404 /// XM_005246405 /// XM_005246406 /// XM_005246407 /// XM_005246408 /// XM_005246409 /// XM_005246410 /// XM_005246411 /// XM_005246412 /// XM_005246413 /// XM_005246414 /// XM_005246415 /// XM_005246416 /// XM_005246417","0001525 // angiogenesis // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007044 // cell-substrate junction assembly // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007161 // calcium-independent cell-matrix adhesion // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009611 // response to wounding // non-traceable author statement /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0016477 // cell migration // non-traceable author statement /// 0018149 // peptide cross-linking // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0042060 // wound healing // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement","0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay","0002020 // protease binding // inferred from physical interaction /// 0005178 // integrin binding // inferred from direct assay /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // non-traceable author statement /// 0008201 // heparin binding // non-traceable author statement /// 0016504 // peptidase activator activity // inferred from electronic annotation","Inflammatory_Response_Pathway // GenMAPP","IPR000083 // Fibronectin, type I // 2.0E-14 /// IPR000083 // Fibronectin, type I // 2.7E-18 /// IPR000083 // Fibronectin, type I // 1.6E-16 /// IPR000083 // Fibronectin, type I // 1.2E-18 /// IPR000083 // Fibronectin, type I // 3.5E-18 /// IPR000083 // Fibronectin, type I // 1.8E-12 /// IPR000083 // Fibronectin, type I // 1.5E-18 /// IPR000083 // Fibronectin, type I // 4.0E-16 /// IPR000083 // Fibronectin, type I // 5.3E-18 /// IPR000083 // Fibronectin, type I // 1.2E-18 /// IPR000083 // Fibronectin, type I // 8.3E-17 /// IPR000083 // Fibronectin, type I // 1.5E-13 /// IPR000083 // Fibronectin, type I // 2.2E-14 /// IPR000083 // Fibronectin, type I // 3.0E-18 /// IPR000083 // Fibronectin, type I // 1.8E-16 /// IPR000083 // Fibronectin, type I // 1.3E-18 /// IPR000083 // Fibronectin, type I // 3.9E-18 /// IPR000083 // Fibronectin, type I // 2.0E-12 /// IPR000083 // Fibronectin, type I // 1.6E-18 /// IPR000083 // Fibronectin, type I // 4.4E-16 /// IPR000083 // Fibronectin, type I // 5.9E-18 /// IPR000083 // Fibronectin, type I // 1.3E-18 /// IPR000083 // Fibronectin, type I // 9.2E-17 /// IPR000083 // Fibronectin, type I // 1.7E-13 /// IPR000083 // Fibronectin, type I // 2.1E-14 /// IPR000083 // Fibronectin, type I // 2.9E-18 /// IPR000083 // Fibronectin, type I // 1.7E-16 /// IPR000083 // Fibronectin, type I // 3.7E-18 /// IPR000083 // Fibronectin, type I // 4.3E-16 /// IPR000083 // Fibronectin, type I // 5.6E-18 /// IPR000083 // Fibronectin, type I // 1.3E-18 /// IPR000083 // Fibronectin, type I // 8.8E-17 /// IPR000083 // Fibronectin, type I // 1.6E-13 /// IPR000083 // Fibronectin, type I // 1.9E-14 /// IPR000083 // Fibronectin, type I // 2.6E-18 /// IPR000083 // Fibronectin, type I // 3.4E-18 /// IPR000083 // Fibronectin, type I // 1.4E-18 /// IPR000083 // Fibronectin, type I // 3.9E-16 /// IPR000083 // Fibronectin, type I // 5.2E-18 /// IPR000083 // Fibronectin, type I // 1.2E-18 /// IPR000083 // Fibronectin, type I // 8.1E-17 /// IPR000083 // Fibronectin, type I // 1.5E-13 /// IPR000083 // Fibronectin, type I // 1.4E-18 /// IPR000083 // Fibronectin, type I // 2.1E-12 /// IPR000083 // Fibronectin, type I // 1.7E-18 /// IPR000083 // Fibronectin, type I // 4.5E-16 /// IPR000083 // Fibronectin, type I // 1.4E-18 /// IPR000083 // Fibronectin, type I // 9.3E-17 /// IPR000083 // Fibronectin, type I // 1.7E-13 /// IPR000083 // Fibronectin, type I // 2.8E-18 /// IPR000083 // Fibronectin, type I // 1.9E-12 /// IPR000083 // Fibronectin, type I // 4.2E-16 /// IPR000083 // Fibronectin, type I // 1.3E-18 /// IPR000083 // Fibronectin, type I // 8.7E-17 /// IPR000083 // Fibronectin, type I // 1.6E-13 /// IPR000083 // Fibronectin, type I // 3.6E-18 /// IPR000083 // Fibronectin, type I // 4.1E-16 /// IPR000083 // Fibronectin, type I // 5.4E-18 /// IPR000083 // Fibronectin, type I // 1.2E-18 /// IPR000083 // Fibronectin, type I // 8.4E-17 /// IPR000083 // Fibronectin, type I // 1.5E-13 /// IPR000083 // Fibronectin, type I // 1.2E-18 /// IPR000083 // Fibronectin, type I // 8.4E-17 /// IPR000083 // Fibronectin, type I // 1.5E-13 /// IPR000083 // Fibronectin, type I // 5.5E-18 /// IPR000083 // Fibronectin, type I // 1.3E-18 /// IPR000083 // Fibronectin, type I // 8.6E-17 /// IPR000083 // Fibronectin, type I // 1.5E-13 /// IPR000083 // Fibronectin, type I // 3.8E-18 /// IPR000083 // Fibronectin, type I // 5.7E-18 /// IPR000083 // Fibronectin, type I // 1.3E-18 /// IPR000083 // Fibronectin, type I // 8.9E-17 /// IPR000083 // Fibronectin, type I // 1.6E-13 /// IPR000562 // Fibronectin, type II, collagen-binding // 1.1E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 6.5E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 1.2E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 7.2E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 6.9E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 6.3E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 7.3E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 6.8E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 6.6E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 6.7E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 7.0E-21 /// IPR003961 // Fibronectin, type III // 2.3E-15 /// IPR003961 // Fibronectin, type III // 5.2E-16 /// IPR003961 // Fibronectin, type III // 8.3E-22 /// IPR003961 // Fibronectin, type III // 2.1E-18 /// IPR003961 // Fibronectin, type III // 6.6E-19 /// IPR003961 // Fibronectin, type III // 6.0E-10 /// IPR003961 // Fibronectin, type III // 1.3E-16 /// IPR003961 // Fibronectin, type III // 3.7E-20 /// IPR003961 // Fibronectin, type III // 6.0E-20 /// IPR003961 // Fibronectin, type III // 4.9E-24 /// IPR003961 // Fibronectin, type III // 1.0E-20 /// IPR003961 // Fibronectin, type III // 1.1E-19 /// IPR003961 // Fibronectin, type III // 1.3E-18 /// IPR003961 // Fibronectin, type III // 4.0E-21 /// IPR003961 // Fibronectin, type III // 5.8E-11 /// IPR003961 // Fibronectin, type III // 2.5E-15 /// IPR003961 // Fibronectin, type III // 5.7E-16 /// IPR003961 // Fibronectin, type III // 9.1E-22 /// IPR003961 // Fibronectin, type III // 2.4E-18 /// IPR003961 // Fibronectin, type III // 7.3E-19 /// IPR003961 // Fibronectin, type III // 6.6E-10 /// IPR003961 // Fibronectin, type III // 1.4E-16 /// IPR003961 // Fibronectin, type III // 8.1E-16 /// IPR003961 // Fibronectin, type III // 4.1E-20 /// IPR003961 // Fibronectin, type III // 6.6E-20 /// IPR003961 // Fibronectin, type III // 5.4E-24 /// IPR003961 // Fibronectin, type III // 1.1E-20 /// IPR003961 // Fibronectin, type III // 1.1E-15 /// IPR003961 // Fibronectin, type III // 1.3E-19 /// IPR003961 // Fibronectin, type III // 1.4E-18 /// IPR003961 // Fibronectin, type III // 4.4E-21 /// IPR003961 // Fibronectin, type III // 6.4E-11 /// IPR003961 // Fibronectin, type III // 2.4E-15 /// IPR003961 // Fibronectin, type III // 5.5E-16 /// IPR003961 // Fibronectin, type III // 8.7E-22 /// IPR003961 // Fibronectin, type III // 2.3E-18 /// IPR003961 // Fibronectin, type III // 7.0E-19 /// IPR003961 // Fibronectin, type III // 6.3E-10 /// IPR003961 // Fibronectin, type III // 3.9E-20 /// IPR003961 // Fibronectin, type III // 6.4E-20 /// IPR003961 // Fibronectin, type III // 5.2E-24 /// IPR003961 // Fibronectin, type III // 1.1E-20 /// IPR003961 // Fibronectin, type III // 1.1E-15 /// IPR003961 // Fibronectin, type III // 1.2E-19 /// IPR003961 // Fibronectin, type III // 1.3E-18 /// IPR003961 // Fibronectin, type III // 4.2E-21 /// IPR003961 // Fibronectin, type III // 6.1E-11 /// IPR003961 // Fibronectin, type III // 2.2E-15 /// IPR003961 // Fibronectin, type III // 5.0E-16 /// IPR003961 // Fibronectin, type III // 8.0E-22 /// IPR003961 // Fibronectin, type III // 6.4E-19 /// IPR003961 // Fibronectin, type III // 5.8E-10 /// IPR003961 // Fibronectin, type III // 1.2E-16 /// IPR003961 // Fibronectin, type III // 3.6E-20 /// IPR003961 // Fibronectin, type III // 5.8E-20 /// IPR003961 // Fibronectin, type III // 4.7E-24 /// IPR003961 // Fibronectin, type III // 9.9E-21 /// IPR003961 // Fibronectin, type III // 1.2E-18 /// IPR003961 // Fibronectin, type III // 3.9E-21 /// IPR003961 // Fibronectin, type III // 8.4E-11 /// IPR003961 // Fibronectin, type III // 2.6E-15 /// IPR003961 // Fibronectin, type III // 5.8E-16 /// IPR003961 // Fibronectin, type III // 9.3E-22 /// IPR003961 // Fibronectin, type III // 7.4E-19 /// IPR003961 // Fibronectin, type III // 6.7E-10 /// IPR003961 // Fibronectin, type III // 8.3E-16 /// IPR003961 // Fibronectin, type III // 6.7E-20 /// IPR003961 // Fibronectin, type III // 5.5E-24 /// IPR003961 // Fibronectin, type III // 1.2E-20 /// IPR003961 // Fibronectin, type III // 1.2E-15 /// IPR003961 // Fibronectin, type III // 4.5E-21 /// IPR003961 // Fibronectin, type III // 9.0E-11 /// IPR003961 // Fibronectin, type III // 5.4E-16 /// IPR003961 // Fibronectin, type III // 8.6E-22 /// IPR003961 // Fibronectin, type III // 2.2E-18 /// IPR003961 // Fibronectin, type III // 6.9E-19 /// IPR003961 // Fibronectin, type III // 6.2E-10 /// IPR003961 // Fibronectin, type III // 6.3E-20 /// IPR003961 // Fibronectin, type III // 5.1E-24 /// IPR003961 // Fibronectin, type III // 6.0E-11 /// IPR003961 // Fibronectin, type III // 5.3E-16 /// IPR003961 // Fibronectin, type III // 8.4E-22 /// IPR003961 // Fibronectin, type III // 6.7E-19 /// IPR003961 // Fibronectin, type III // 6.1E-10 /// IPR003961 // Fibronectin, type III // 6.1E-20 /// IPR003961 // Fibronectin, type III // 1.2E-19 /// IPR003961 // Fibronectin, type III // 5.8E-11 /// IPR003961 // Fibronectin, type III // 7.5E-16 /// IPR003961 // Fibronectin, type III // 3.7E-20 /// IPR003961 // Fibronectin, type III // 6.1E-20 /// IPR003961 // Fibronectin, type III // 4.9E-24 /// IPR003961 // Fibronectin, type III // 1.0E-20 /// IPR003961 // Fibronectin, type III // 1.2E-19 /// IPR003961 // Fibronectin, type III // 1.3E-18 /// IPR003961 // Fibronectin, type III // 4.0E-21 /// IPR003961 // Fibronectin, type III // 8.8E-11 /// IPR003961 // Fibronectin, type III // 8.5E-22 /// IPR003961 // Fibronectin, type III // 6.8E-19 /// IPR003961 // Fibronectin, type III // 3.8E-20 /// IPR003961 // Fibronectin, type III // 6.2E-20 /// IPR003961 // Fibronectin, type III // 5.0E-24 /// IPR003961 // Fibronectin, type III // 4.1E-21 /// IPR003961 // Fibronectin, type III // 8.3E-11 /// IPR003961 // Fibronectin, type III // 5.6E-16 /// IPR003961 // Fibronectin, type III // 8.9E-22 /// IPR003961 // Fibronectin, type III // 7.1E-19 /// IPR003961 // Fibronectin, type III // 6.4E-10 /// IPR003961 // Fibronectin, type III // 4.0E-20 /// IPR003961 // Fibronectin, type III // 6.5E-20 /// IPR003961 // Fibronectin, type III // 1.4E-18 /// IPR003961 // Fibronectin, type III // 4.3E-21 /// IPR003961 // Fibronectin, type III // 8.7E-11"
"212473_s_at",1.259103576,1.191464881,1.030582374,"UP","BE965029","chr11:12282278-12285332 (+) // 96.98 // p15.3","microtubule associated monooxygenase, calponin and LIM domain containing 2","MICAL2","ENSG00000133816 /// OTTHUMG00000165744","9645","608881","NP_001269592 /// NP_001269593 /// NP_001269594 /// NP_001269595 /// NP_001269596 /// NP_001269597 /// NP_055447 /// XP_005253306 /// XP_005253308 /// XP_006718454 /// XP_006718455 /// XP_006718456","NM_001282663 /// NM_001282664 /// NM_001282665 /// NM_001282666 /// NM_001282667 /// NM_001282668 /// NM_014632 /// XM_005253249 /// XM_005253251 /// XM_006718391 /// XM_006718392 /// XM_006718393","0001947 // heart looping // inferred from sequence or structural similarity /// 0007010 // cytoskeleton organization // inferred from direct assay /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0010735 // positive regulation of transcription via serum response element binding // inferred from mutant phenotype /// 0019417 // sulfur oxidation // inferred from direct assay /// 0019417 // sulfur oxidation // inferred from sequence or structural similarity /// 0030042 // actin filament depolymerization // inferred from direct assay /// 0030042 // actin filament depolymerization // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // inferred from sequence or structural similarity","0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation","0003779 // actin binding // inferred from direct assay /// 0003779 // actin binding // inferred from sequence or structural similarity /// 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016709 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen // inferred from sequence or structural similarity /// 0043914 // NADPH:sulfur oxidoreductase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0071949 // FAD binding // inferred from sequence or structural similarity","---","IPR001715 // Calponin homology domain // 5.9E-24 /// IPR001715 // Calponin homology domain // 4.6E-24 /// IPR001715 // Calponin homology domain // 5.8E-24 /// IPR001715 // Calponin homology domain // 4.9E-24 /// IPR001781 // Zinc finger, LIM-type // 2.7E-11 /// IPR001781 // Zinc finger, LIM-type // 2.2E-11 /// IPR001781 // Zinc finger, LIM-type // 2.7E-11 /// IPR001781 // Zinc finger, LIM-type // 2.3E-11 /// IPR002938 // Monooxygenase, FAD-binding // 5.6E-10 /// IPR002938 // Monooxygenase, FAD-binding // 4.5E-10 /// IPR002938 // Monooxygenase, FAD-binding // 5.4E-10 /// IPR002938 // Monooxygenase, FAD-binding // 4.7E-10 /// IPR003953 // FAD binding domain // 1.6E-8 /// IPR003953 // FAD binding domain // 1.3E-8 /// IPR003953 // FAD binding domain // 1.5E-8 /// IPR022613 // Calmodulin-regulated spectrin-associated protein, CH domain // 6.6E-16 /// IPR022613 // Calmodulin-regulated spectrin-associated protein, CH domain // 5.2E-16 /// IPR022613 // Calmodulin-regulated spectrin-associated protein, CH domain // 6.4E-16 /// IPR022613 // Calmodulin-regulated spectrin-associated protein, CH domain // 5.5E-16"
"212531_at",1.303233255,1.941395092,2.403694905,"UP","NM_005564","chr9:130911748-130915731 (+) // 86.33 // q34.11","lipocalin 2","LCN2","ENSG00000148346 /// OTTHUMG00000020734","3934","600181","NP_005555","NM_005564","0002376 // immune system process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0009617 // response to bacterium // inferred from electronic annotation /// 0009635 // response to herbicide // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0015891 // siderophore transport // inferred from sequence or structural similarity /// 0031346 // positive regulation of cell projection organization // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0031669 // cellular response to nutrient levels // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0045087 // innate immune response // inferred from sequence or structural similarity /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0070207 // protein homotrimerization // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation /// 0071347 // cellular response to interleukin-1 // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0097192 // extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation","0005576 // extracellular region // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0002020 // protease binding // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0036094 // small molecule binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation","---","IPR000566 // Lipocalin/cytosolic fatty-acid binding domain // 5.7E-27 /// IPR000566 // Lipocalin/cytosolic fatty-acid binding domain // 9.6E-26"
"212611_at",1.595771039,2.224734944,2.345297158,"UP","AV728526","chr11:58939752-58976057 (+) // 95.27 // q12.1","deltex 4, E3 ubiquitin ligase","DTX4","ENSG00000110042 /// OTTHUMG00000167336","23220","---","NP_055992 /// XP_006718546","NM_015177 /// XM_006718483","0007219 // Notch signaling pathway // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0032479 // regulation of type I interferon production // traceable author statement /// 0032481 // positive regulation of type I interferon production // traceable author statement /// 0045087 // innate immune response // traceable author statement","0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement","0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","Cell_cycle_KEGG // GenMAPP","IPR004170 // WWE domain // 1.8E-29 /// IPR004170 // WWE domain // 3.8E-31 /// IPR018957 // Zinc finger, C3HC4 RING-type // 1.0E-8"
"212803_at",1.143558926,1.169255927,1.327974067,"UP","BF337329","chr12:57482791-57489258 (+) // 98.86 // q13.3","NGFI-A binding protein 2 (EGR1 binding protein 2)","NAB2","ENSG00000166886 /// OTTHUMG00000171192","4665","602381","NP_005958 /// XP_005268951","NM_005967 /// XM_005268894","0001958 // endochondral ossification // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0014037 // Schwann cell differentiation // inferred from electronic annotation /// 0016480 // negative regulation of transcription from RNA polymerase III promoter // inferred from direct assay /// 0042552 // myelination // inferred from electronic annotation /// 0045682 // regulation of epidermis development // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation","0005634 // nucleus // inferred from electronic annotation","0003714 // transcription corepressor activity // traceable author statement /// 0008134 // transcription factor binding // inferred from electronic annotation","---","IPR006988 // Nab, N-terminal // 1.2E-51 /// IPR006988 // Nab, N-terminal // 9.7E-52 /// IPR006989 // NAB co-repressor, domain // 2.0E-78 /// IPR006989 // NAB co-repressor, domain // 1.5E-78"
"212843_at",-2.318428472,-1.810214849,-1.037610467,"DOWN","AA126505","chr11:113103514-113148620 (+) // 94.51 // q23.2","neural cell adhesion molecule 1","NCAM1","ENSG00000149294 /// OTTHUMG00000167196","4684","116930","NP_000606 /// NP_001070150 /// NP_001229536 /// NP_001229537 /// NP_851996","NM_000615 /// NM_001076682 /// NM_001242607 /// NM_001242608 /// NM_181351","0001928 // regulation of exocyst assembly // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0031175 // neuron projection development // inferred from electronic annotation /// 0034109 // homotypic cell-cell adhesion // inferred from electronic annotation /// 0050850 // positive regulation of calcium-mediated signaling // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement","0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction","---","IPR003961 // Fibronectin, type III // 8.1E-16 /// IPR003961 // Fibronectin, type III // 5.2E-13 /// IPR013098 // Immunoglobulin I-set // 1.0E-21 /// IPR013098 // Immunoglobulin I-set // 1.6E-11 /// IPR013098 // Immunoglobulin I-set // 8.3E-23 /// IPR013098 // Immunoglobulin I-set // 3.0E-18 /// IPR013098 // Immunoglobulin I-set // 5.1E-15 /// IPR013106 // Immunoglobulin V-set domain // 3.0E-8 /// IPR013106 // Immunoglobulin V-set domain // 2.6E-8 /// IPR013106 // Immunoglobulin V-set domain // 1.8E-8 /// IPR013151 // Immunoglobulin // 8.9E-9 /// IPR013151 // Immunoglobulin // 9.4E-12 /// IPR013151 // Immunoglobulin // 2.2E-10 /// IPR013151 // Immunoglobulin // 3.4E-11"
"212850_s_at",3.706692399,3.378743567,3.02539456,"UP","AA584297","chr11:46878417-46917821 (-) // 98.48 // p11.2","low density lipoprotein receptor-related protein 4","LRP4","ENSG00000134569 /// OTTHUMG00000166700","4038","212780 /// 604270 /// 614305","NP_002325 /// XP_005252980 /// XP_006718294","NM_002334 /// XM_005252923 /// XM_006718231","0001822 // kidney development // inferred from direct assay /// 0001932 // regulation of protein phosphorylation // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0009953 // dorsal/ventral pattern formation // inferred from electronic annotation /// 0009954 // proximal/distal pattern formation // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030279 // negative regulation of ossification // inferred from mutant phenotype /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042733 // embryonic digit morphogenesis // inferred from electronic annotation /// 0043113 // receptor clustering // inferred from electronic annotation /// 0048813 // dendrite morphogenesis // inferred from sequence or structural similarity /// 0048856 // anatomical structure development // inferred from electronic annotation /// 0050771 // negative regulation of axonogenesis // inferred from sequence or structural similarity /// 0050808 // synapse organization // inferred from sequence or structural similarity /// 0051124 // synaptic growth at neuromuscular junction // inferred from sequence or structural similarity /// 0051290 // protein heterotetramerization // inferred from sequence or structural similarity /// 0060173 // limb development // inferred from direct assay /// 0071340 // skeletal muscle acetylcholine-gated channel clustering // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from direct assay /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from mutant phenotype /// 0097104 // postsynaptic membrane assembly // inferred from sequence or structural similarity /// 0097105 // presynaptic membrane assembly // inferred from sequence or structural similarity /// 1901631 // positive regulation of presynaptic membrane organization // inferred from sequence or structural similarity","0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016600 // flotillin complex // inferred from sequence or structural similarity /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0031594 // neuromuscular junction // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0097060 // synaptic membrane // inferred from sequence or structural similarity","0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030971 // receptor tyrosine kinase binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0097110 // scaffold protein binding // inferred from sequence or structural similarity","---","IPR000033 // LDLR class B repeat // 5.4E-11 /// IPR000033 // LDLR class B repeat // 1.4E-16 /// IPR000033 // LDLR class B repeat // 2.6E-14 /// IPR000033 // LDLR class B repeat // 9.8E-15 /// IPR000033 // LDLR class B repeat // 2.3E-12 /// IPR000033 // LDLR class B repeat // 6.3E-14 /// IPR000033 // LDLR class B repeat // 7.9E-15 /// IPR000033 // LDLR class B repeat // 1.9E-11 /// IPR000033 // LDLR class B repeat // 1.1E-8 /// IPR000033 // LDLR class B repeat // 1.0E-11 /// IPR000033 // LDLR class B repeat // 1.3E-13 /// IPR000033 // LDLR class B repeat // 3.9E-17 /// IPR000033 // LDLR class B repeat // 8.5E-9 /// IPR000033 // LDLR class B repeat // 7.9E-13 /// IPR000033 // LDLR class B repeat // 8.2E-17 /// IPR000033 // LDLR class B repeat // 3.0E-9 /// IPR001881 // EGF-like calcium-binding domain // 2.9E-9 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 4.1E-11 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 3.7E-16 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 5.4E-13 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 5.4E-16 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 7.1E-13 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 6.0E-14 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 3.9E-16 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.3E-12"
"212992_at",2.340345255,2.915003272,2.650741139,"UP","AI935123","chr14:105403589-105405774 (-) // 98.69 // q32.33","AHNAK nucleoprotein 2","AHNAK2","ENSG00000185567 /// OTTHUMG00000170765","113146","608570","NP_612429 /// XP_005267356","NM_138420 /// XM_005267299","0001778 // plasma membrane repair // inferred from sequence or structural similarity","0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0030315 // T-tubule // non-traceable author statement /// 0030659 // cytoplasmic vesicle membrane // inferred from sequence or structural similarity /// 0042383 // sarcolemma // non-traceable author statement /// 0043034 // costamere // inferred from sequence or structural similarity","0005515 // protein binding // inferred from physical interaction","---","---"
"213068_at",-2.832138234,-1.751937349,-1.428936193,"DOWN","AI146848","chr1:168664705-168698421 (-) // 96.86 // q24.2","dermatopontin","DPT","ENSG00000143196 /// OTTHUMG00000034554","1805","125597","NP_001928","NM_001937","0007155 // cell adhesion // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0030199 // collagen fibril organization // inferred from electronic annotation","0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay","---","---","---"
"213071_at",-2.771383244,-1.707995558,-2.49732711,"DOWN","AL049798","chr1:168664705-168698421 (-) // 96.86 // q24.2","dermatopontin","DPT","ENSG00000143196 /// OTTHUMG00000034554","1805","125597","NP_001928","NM_001937","0007155 // cell adhesion // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0030199 // collagen fibril organization // inferred from electronic annotation","0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay","---","---","---"
"213103_at",-1.241549922,-1.553097549,-1.3186384,"DOWN","AA128023","chr13:33677272-33780143 (-) // 94.64 // q13.1","StAR-related lipid transfer (START) domain containing 13","STARD13","ENSG00000133121 /// OTTHUMG00000016708","90627","609866","NP_001230395 /// NP_001230403 /// NP_001230405 /// NP_443083 /// NP_821074 /// NP_821075 /// XP_005266643 /// XP_006719951 /// XP_006719952","NM_001243466 /// NM_001243474 /// NM_001243476 /// NM_052851 /// NM_178006 /// NM_178007 /// NM_178008 /// XM_005266586 /// XM_006719888 /// XM_006719889","0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement","0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005811 // lipid particle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation","0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation","---","IPR000198 // Rho GTPase-activating protein domain // 2.1E-40 /// IPR000198 // Rho GTPase-activating protein domain // 2.1E-40 /// IPR000198 // Rho GTPase-activating protein domain // 1.2E-40 /// IPR002913 // START domain // 1.3E-42 /// IPR002913 // START domain // 1.3E-42 /// IPR002913 // START domain // 7.2E-43 /// IPR011510 // Sterile alpha motif, type 2 // 2.6E-9 /// IPR011510 // Sterile alpha motif, type 2 // 2.6E-9"
"213129_s_at",-1.17503275,-1.210542736,-1.038706898,"DOWN","AI970157","chr16:81115542-81129954 (-) // 98.49 // q23.2","glycine cleavage system protein H (aminomethyl carrier) /// glycine cleavage system H protein, mitochondrial-like","GCSH /// LOC101060817","ENSG00000140905 /// OTTHUMG00000137626","2653 /// 101060817","238330 /// 605899","NP_004474 /// XP_003960941","NM_004483 /// NR_033249 /// XM_003960892","0006546 // glycine catabolic process // traceable author statement /// 0019464 // glycine decarboxylation via glycine cleavage system // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0032259 // methylation // traceable author statement","0005739 // mitochondrion // inferred from electronic annotation /// 0005960 // glycine cleavage complex // inferred from electronic annotation","0004047 // aminomethyltransferase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from electronic annotation","---","IPR002930 // Glycine cleavage system H-protein // 4.1E-54 /// IPR002930 // Glycine cleavage system H-protein // 3.2E-9"
"213135_at",2.307716936,2.052659156,2.104482256,"UP","U90902","chr21:32490735-32492552 (-) // 96.71 // q22.11","T-cell lymphoma invasion and metastasis 1","TIAM1","ENSG00000156299 /// OTTHUMG00000084869","7074","600687","NP_003244 /// XP_005261094 /// XP_005261095 /// XP_005261096 /// XP_005261097","NM_003253 /// XM_005261037 /// XM_005261038 /// XM_005261039 /// XM_005261040","0007160 // cell-matrix adhesion // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0016477 // cell migration // inferred from mutant phenotype /// 0016601 // Rac protein signal transduction // inferred from mutant phenotype /// 0032314 // regulation of Rac GTPase activity // inferred from mutant phenotype /// 0032319 // regulation of Rho GTPase activity // traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // traceable author statement /// 0032855 // positive regulation of Rac GTPase activity // inferred from mutant phenotype /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048013 // ephrin receptor signaling pathway // inferred from electronic annotation /// 0050772 // positive regulation of axonogenesis // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement","0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // inferred from direct assay /// 0044291 // cell-cell contact zone // inferred from direct assay","0005057 // receptor signaling protein activity // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0030676 // Rac guanyl-nucleotide exchange factor activity // inferred from mutant phenotype /// 0046875 // ephrin receptor binding // inferred from electronic annotation","---","IPR000219 // Dbl homology (DH) domain // 4.2E-46 /// IPR000219 // Dbl homology (DH) domain // 4.0E-46 /// IPR001478 // PDZ domain // 3.9E-11 /// IPR001478 // PDZ domain // 3.7E-11 /// IPR001849 // Pleckstrin homology domain // 3.2E-15 /// IPR001849 // Pleckstrin homology domain // 3.1E-15 /// IPR003116 // Raf-like Ras-binding // 2.4E-22 /// IPR003116 // Raf-like Ras-binding // 6.5E-13"
"213241_at",2.106928868,2.36477064,2.027206805,"UP","AF035307","chr12:94699241-94701444 (+) // 91.83 // q22","plexin C1","PLXNC1","ENSG00000136040 /// OTTHUMG00000170235","10154","604259","NP_005752 /// XP_006719249","NM_005761 /// NR_037687 /// XM_006719186","0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement","0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0004872 // receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction","---","IPR002165 // Plexin // 4.5E-14 /// IPR002909 // IPT domain // 2.4E-11 /// IPR002909 // IPT domain // 4.8E-9 /// IPR013548 // Plexin, cytoplasmic RasGAP domain // 8.3E-223"
"213258_at",-1.556390254,-1.430820365,-1.251547938,"DOWN","BF511231","chr2:188328956-188330208 (-) // 77.08 // q32.1","tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)","TFPI","ENSG00000003436 /// OTTHUMG00000132634","7035","152310","NP_001027452 /// NP_006278 /// XP_005246875 /// XP_005246876 /// XP_005246877 /// XP_006712783","NM_001032281 /// NM_006287 /// XM_005246818 /// XM_005246819 /// XM_005246820 /// XM_006712720","0007596 // blood coagulation // traceable author statement /// 0007598 // blood coagulation, extrinsic pathway // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // traceable author statement","0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation","0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation","---","IPR002223 // Proteinase inhibitor I2, Kunitz metazoa // 2.7E-22 /// IPR002223 // Proteinase inhibitor I2, Kunitz metazoa // 5.7E-23 /// IPR002223 // Proteinase inhibitor I2, Kunitz metazoa // 3.4E-23"
"213307_at",-1.4600794,-1.261626221,-1.34485441,"DOWN","AF131790","chr11:70314274-70348964 (-) // 97.85 // q13.3","SH3 and multiple ankyrin repeat domains 2","SHANK2","ENSG00000162105 /// ENSG00000268430 /// OTTHUMG00000154615","22941","603290 /// 613436","NP_036441 /// NP_573573 /// XP_005277987 /// XP_005277989 /// XP_006718540 /// XP_006718541","NM_012309 /// NM_133266 /// NR_110766 /// XM_005277930 /// XM_005277932 /// XM_006718477 /// XM_006718478","0007416 // synapse assembly // inferred from sequence or structural similarity /// 0007612 // learning // inferred from mutant phenotype /// 0030534 // adult behavior // inferred from mutant phenotype /// 0035176 // social behavior // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0060291 // long-term synaptic potentiation // inferred from sequence or structural similarity /// 0060292 // long term synaptic depression // inferred from sequence or structural similarity /// 0071625 // vocalization behavior // inferred from mutant phenotype","0001750 // photoreceptor outer segment // inferred from sequence or structural similarity /// 0001917 // photoreceptor inner segment // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005883 // neurofilament // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0008328 // ionotropic glutamate receptor complex // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031526 // brush border membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity /// 0060170 // ciliary membrane // inferred from sequence or structural similarity","0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0030160 // GKAP/Homer scaffold activity // non-traceable author statement /// 0035255 // ionotropic glutamate receptor binding // inferred from sequence or structural similarity","---","IPR001452 // SH3 domain // 3.2E-9 /// IPR001452 // SH3 domain // 5.0E-9 /// IPR001478 // PDZ domain // 6.9E-12 /// IPR001478 // PDZ domain // 1.4E-11 /// IPR001478 // PDZ domain // 6.9E-12 /// IPR001478 // PDZ domain // 2.2E-11 /// IPR011510 // Sterile alpha motif, type 2 // 3.5E-22 /// IPR011510 // Sterile alpha motif, type 2 // 7.0E-22 /// IPR011510 // Sterile alpha motif, type 2 // 3.5E-22 /// IPR011510 // Sterile alpha motif, type 2 // 1.1E-21 /// IPR011511 // Variant SH3 domain // 1.0E-15 /// IPR011511 // Variant SH3 domain // 1.6E-15 /// IPR021129 // Sterile alpha motif, type 1 // 2.8E-23 /// IPR021129 // Sterile alpha motif, type 1 // 5.7E-23 /// IPR021129 // Sterile alpha motif, type 1 // 2.8E-23 /// IPR021129 // Sterile alpha motif, type 1 // 8.8E-23"
"213308_at",-1.876676481,-1.937871692,-1.88567224,"DOWN","BF435773","chr11:70314274-70348964 (-) // 97.85 // q13.3","SH3 and multiple ankyrin repeat domains 2","SHANK2","ENSG00000162105 /// ENSG00000268430 /// OTTHUMG00000154615","22941","603290 /// 613436","NP_036441 /// NP_573573 /// XP_005277987 /// XP_005277989 /// XP_006718540 /// XP_006718541","NM_012309 /// NM_133266 /// NR_110766 /// XM_005277930 /// XM_005277932 /// XM_006718477 /// XM_006718478","0007416 // synapse assembly // inferred from sequence or structural similarity /// 0007612 // learning // inferred from mutant phenotype /// 0030534 // adult behavior // inferred from mutant phenotype /// 0035176 // social behavior // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0060291 // long-term synaptic potentiation // inferred from sequence or structural similarity /// 0060292 // long term synaptic depression // inferred from sequence or structural similarity /// 0071625 // vocalization behavior // inferred from mutant phenotype","0001750 // photoreceptor outer segment // inferred from sequence or structural similarity /// 0001917 // photoreceptor inner segment // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005883 // neurofilament // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0008328 // ionotropic glutamate receptor complex // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031526 // brush border membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity /// 0060170 // ciliary membrane // inferred from sequence or structural similarity","0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0030160 // GKAP/Homer scaffold activity // non-traceable author statement /// 0035255 // ionotropic glutamate receptor binding // inferred from sequence or structural similarity","---","IPR001452 // SH3 domain // 5.0E-9 /// IPR001452 // SH3 domain // 3.2E-9 /// IPR001452 // SH3 domain // 5.0E-9 /// IPR001452 // SH3 domain // 3.2E-9 /// IPR001478 // PDZ domain // 6.9E-12 /// IPR001478 // PDZ domain // 2.2E-11 /// IPR001478 // PDZ domain // 1.4E-11 /// IPR001478 // PDZ domain // 6.9E-12 /// IPR001478 // PDZ domain // 2.2E-11 /// IPR001478 // PDZ domain // 1.4E-11 /// IPR011510 // Sterile alpha motif, type 2 // 3.5E-22 /// IPR011510 // Sterile alpha motif, type 2 // 2.1E-22 /// IPR011510 // Sterile alpha motif, type 2 // 1.1E-21 /// IPR011510 // Sterile alpha motif, type 2 // 7.0E-22 /// IPR011510 // Sterile alpha motif, type 2 // 3.5E-22 /// IPR011510 // Sterile alpha motif, type 2 // 2.1E-22 /// IPR011510 // Sterile alpha motif, type 2 // 1.1E-21 /// IPR011510 // Sterile alpha motif, type 2 // 7.0E-22 /// IPR011511 // Variant SH3 domain // 1.6E-15 /// IPR011511 // Variant SH3 domain // 1.0E-15 /// IPR011511 // Variant SH3 domain // 1.6E-15 /// IPR011511 // Variant SH3 domain // 1.0E-15 /// IPR021129 // Sterile alpha motif, type 1 // 2.8E-23 /// IPR021129 // Sterile alpha motif, type 1 // 1.7E-23 /// IPR021129 // Sterile alpha motif, type 1 // 8.9E-23 /// IPR021129 // Sterile alpha motif, type 1 // 5.7E-23 /// IPR021129 // Sterile alpha motif, type 1 // 2.8E-23 /// IPR021129 // Sterile alpha motif, type 1 // 1.7E-23 /// IPR021129 // Sterile alpha motif, type 1 // 8.8E-23 /// IPR021129 // Sterile alpha motif, type 1 // 5.7E-23"
"213411_at",-1.574410365,-1.280557881,-1.286527546,"DOWN","AW242701","chr7:87828317-87832204 (+) // 99.26 // q21.12","ADAM metallopeptidase domain 22","ADAM22","ENSG00000008277 /// OTTHUMG00000137417","53616","603709","NP_004185 /// NP_057435 /// NP_068367 /// NP_068368 /// NP_068369 /// XP_005250502 /// XP_006716091 /// XP_006716092","NM_004194 /// NM_016351 /// NM_021721 /// NM_021722 /// NM_021723 /// XM_005250445 /// XM_006716028 /// XM_006716029","0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // non-traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0014037 // Schwann cell differentiation // inferred from electronic annotation /// 0022011 // myelination in peripheral nervous system // inferred from electronic annotation /// 0042063 // gliogenesis // inferred from electronic annotation","0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement","0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005178 // integrin binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation","---","IPR001590 // Peptidase M12B, ADAM/reprolysin // 1.7E-60 /// IPR001590 // Peptidase M12B, ADAM/reprolysin // 1.8E-60 /// IPR001762 // Blood coagulation inhibitor, Disintegrin // 6.4E-22 /// IPR001762 // Blood coagulation inhibitor, Disintegrin // 6.7E-22 /// IPR002870 // Peptidase M12B, propeptide // 6.9E-36 /// IPR002870 // Peptidase M12B, propeptide // 7.3E-36 /// IPR006586 // ADAM, cysteine-rich // 2.5E-32 /// IPR006586 // ADAM, cysteine-rich // 2.6E-32"
"213422_s_at",1.381871765,1.59216539,1.778355225,"UP","AW888223","chr1:1288071-1293913 (-) // 96.98 // p36.33","matrix-remodelling associated 8","MXRA8","ENSG00000162576 /// OTTHUMG00000002973","54587","---","NP_001269511 /// NP_001269512 /// NP_001269513 /// NP_001269514 /// NP_115724 /// XP_005244815 /// XP_006710765","NM_001282582 /// NM_001282583 /// NM_001282584 /// NM_001282585 /// NM_032348 /// XM_005244758 /// XM_006710702","0060857 // establishment of glial blood-brain barrier // inferred from sequence or structural similarity","0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005515 // protein binding // inferred from electronic annotation","---","IPR013106 // Immunoglobulin V-set domain // 1.2E-10 /// IPR013106 // Immunoglobulin V-set domain // 5.7E-14 /// IPR013106 // Immunoglobulin V-set domain // 1.3E-10 /// IPR013106 // Immunoglobulin V-set domain // 5.9E-14 /// IPR013106 // Immunoglobulin V-set domain // 1.2E-10 /// IPR013106 // Immunoglobulin V-set domain // 5.5E-14 /// IPR013106 // Immunoglobulin V-set domain // 1.1E-14"
"213537_at",1.474970339,1.058061296,1.084193709,"UP","AI128225","chr6:33035436-33041416 (-) // 69.41 // p21.32","major histocompatibility complex, class II, DP alpha 1","HLA-DPA1","ENSG00000168384 /// ENSG00000206291 /// ENSG00000224103 /// ENSG00000228163 /// ENSG00000229685 /// ENSG00000231389 /// ENSG00000235844 /// ENSG00000236177 /// OTTHUMG00000012625 /// OTTHUMG00000031058 /// OTTHUMG00000031328 /// OTTHUMG00000140241 /// OTTHUMG00000148836 /// OTTHUMG00000149106 /// OTTHUMG00000149363 /// OTTHUMG00000149624","3113","142880","NP_001229453 /// NP_001229454 /// NP_291032","NM_001242524 /// NM_001242525 /// NM_033554","0002376 // immune system process // inferred from electronic annotation /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // inferred from mutant phenotype /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0032729 // positive regulation of interferon-gamma production // inferred from mutant phenotype /// 0042102 // positive regulation of T cell proliferation // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0050870 // positive regulation of T cell activation // inferred from mutant phenotype /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0071346 // cellular response to interferon-gamma // inferred from direct assay","0000139 // Golgi membrane // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from mutant phenotype /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042613 // MHC class II protein complex // inferred from direct assay /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement","0005515 // protein binding // inferred from electronic annotation /// 0032395 // MHC class II receptor activity // non-traceable author statement /// 0042605 // peptide antigen binding // inferred from direct assay","---","IPR003597 // Immunoglobulin C1-set // 1.0E-27"
"213553_x_at",1.569228833,1.326204096,1.142081767,"UP","W79394","chr19:45412631-45434577 (+) // 49.71 // q13.32","apolipoprotein C-I","APOC1","ENSG00000130208 /// OTTHUMG00000180844","341","107710","NP_001636 /// XP_005258912","NM_001645 /// XM_005258855","0006629 // lipid metabolic process // traceable author statement /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0010873 // positive regulation of cholesterol esterification // traceable author statement /// 0010900 // negative regulation of phosphatidylcholine catabolic process // inferred from direct assay /// 0010916 // negative regulation of very-low-density lipoprotein particle clearance // inferred from direct assay /// 0032374 // regulation of cholesterol transport // inferred by curator /// 0032375 // negative regulation of cholesterol transport // inferred from direct assay /// 0033344 // cholesterol efflux // inferred from direct assay /// 0033700 // phospholipid efflux // inferred from direct assay /// 0034369 // plasma lipoprotein particle remodeling // inferred from direct assay /// 0034375 // high-density lipoprotein particle remodeling // traceable author statement /// 0034379 // very-low-density lipoprotein particle assembly // traceable author statement /// 0034382 // chylomicron remnant clearance // inferred from direct assay /// 0034447 // very-low-density lipoprotein particle clearance // inferred from genetic interaction /// 0042157 // lipoprotein metabolic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement /// 0045717 // negative regulation of fatty acid biosynthetic process // inferred from direct assay /// 0045833 // negative regulation of lipid metabolic process // inferred from direct assay /// 0048261 // negative regulation of receptor-mediated endocytosis // inferred from direct assay /// 0050995 // negative regulation of lipid catabolic process // inferred from direct assay /// 0051005 // negative regulation of lipoprotein lipase activity // inferred from direct assay","0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0034361 // very-low-density lipoprotein particle // inferred from direct assay /// 0034364 // high-density lipoprotein particle // inferred from direct assay /// 0042627 // chylomicron // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0004859 // phospholipase inhibitor activity // inferred from direct assay /// 0005504 // fatty acid binding // inferred from direct assay /// 0031210 // phosphatidylcholine binding // traceable author statement /// 0055102 // lipase inhibitor activity // inferred from direct assay /// 0060228 // phosphatidylcholine-sterol O-acyltransferase activator activity // traceable author statement","Statin_Pathway_PharmGKB // GenMAPP","IPR006781 // Apolipoprotein C-I // 1.4E-31 /// IPR006781 // Apolipoprotein C-I // 4.4E-29 /// IPR006781 // Apolipoprotein C-I // 1.5E-19 /// IPR006781 // Apolipoprotein C-I // 4.5E-13 /// IPR006781 // Apolipoprotein C-I // 2.2E-20 /// IPR006781 // Apolipoprotein C-I // 7.2E-20"
"213558_at",-1.040705478,-1.035035946,-1.307549894,"DOWN","AB011131","chr7:82449795-82546134 (-) // 99.12 // q21.11","piccolo presynaptic cytomatrix protein","PCLO","ENSG00000186472 /// OTTHUMG00000154853","27445","604918","NP_055325 /// NP_149015 /// XP_006715989","NM_014510 /// NM_033026 /// XM_006715926","0006810 // transport // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016079 // synaptic vesicle exocytosis // non-traceable author statement /// 0017157 // regulation of exocytosis // inferred from electronic annotation /// 0019933 // cAMP-mediated signaling // inferred from electronic annotation /// 0030073 // insulin secretion // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation","0005856 // cytoskeleton // non-traceable author statement /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from sequence or structural similarity","0005215 // transporter activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0005522 // profilin binding // inferred from sequence or structural similarity /// 0005544 // calcium-dependent phospholipid binding // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000008 // C2 domain // 5.1E-25 /// IPR001478 // PDZ domain // 9.1E-12 /// IPR008899 // Zinc finger, piccolo-type // 8.9E-36 /// IPR008899 // Zinc finger, piccolo-type // 2.1E-37"
"213601_at",2.565640623,1.500537172,1.76723461,"UP","AB011537","chr10:98757795-98807756 (-) // 93.71 // q24.1","slit homolog 1 (Drosophila)","SLIT1","ENSG00000187122 /// OTTHUMG00000018843","6585","603742","NP_003052","NM_003061","0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007411 // axon guidance // inferred from direct assay /// 0007411 // axon guidance // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0008045 // motor neuron axon guidance // inferred from mutant phenotype /// 0021510 // spinal cord development // inferred from electronic annotation /// 0021772 // olfactory bulb development // inferred from electronic annotation /// 0021834 // chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration // inferred from direct assay /// 0022028 // tangential migration from the subventricular zone to the olfactory bulb // inferred from electronic annotation /// 0022029 // telencephalon cell migration // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031290 // retinal ganglion cell axon guidance // inferred from electronic annotation /// 0033563 // dorsal/ventral axon guidance // inferred from electronic annotation /// 0040023 // establishment of nucleus localization // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation /// 0048843 // negative regulation of axon extension involved in axon guidance // inferred from electronic annotation /// 0048846 // axon extension involved in axon guidance // inferred from direct assay /// 0048853 // forebrain morphogenesis // non-traceable author statement /// 0050919 // negative chemotaxis // inferred from direct assay /// 0051964 // negative regulation of synapse assembly // inferred from sequence or structural similarity","0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // non-traceable author statement /// 0005737 // cytoplasm // inferred from direct assay","0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0043395 // heparan sulfate proteoglycan binding // inferred from electronic annotation /// 0048495 // Roundabout binding // inferred from physical interaction","---","IPR000372 // Leucine-rich repeat-containing N-terminal // 1.2E-11 /// IPR000372 // Leucine-rich repeat-containing N-terminal // 3.8E-11 /// IPR000372 // Leucine-rich repeat-containing N-terminal // 6.1E-10 /// IPR000372 // Leucine-rich repeat-containing N-terminal // 1.6E-8 /// IPR000483 // Cysteine-rich flanking region, C-terminal // 9.9E-7 /// IPR000483 // Cysteine-rich flanking region, C-terminal // 7.6E-4 /// IPR000483 // Cysteine-rich flanking region, C-terminal // 1.9E-6 /// IPR000483 // Cysteine-rich flanking region, C-terminal // 9.9E-5 /// IPR000742 // Epidermal growth factor-like domain // 8.0E-10 /// IPR000742 // Epidermal growth factor-like domain // 1.9E-8 /// IPR000742 // Epidermal growth factor-like domain // 1.8E-9 /// IPR001611 // Leucine-rich repeat // 3.6E-5 /// IPR001611 // Leucine-rich repeat // 4.4E-5 /// IPR001611 // Leucine-rich repeat // 4.0E-4 /// IPR001611 // Leucine-rich repeat // 2.0E-4 /// IPR001611 // Leucine-rich repeat // 2.8E-4 /// IPR001611 // Leucine-rich repeat // 2.8E-4 /// IPR001791 // Laminin G domain // 2.1E-31 /// IPR001791 // Laminin G domain // 4.9E-30"
"213629_x_at",-1.94706042,-1.678216021,-2.018216612,"DOWN","BF246115","chr16:56691834-56693215 (+) // 89.67 // q12.2","metallothionein 1F","MT1F","ENSG00000198417 /// OTTHUMG00000176838","4494","156352","NP_005940","NM_005949","0045926 // negative regulation of growth // inferred from sequence or structural similarity /// 0071276 // cellular response to cadmium ion // inferred from expression pattern /// 0071294 // cellular response to zinc ion // inferred from sequence or structural similarity","0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity","0005507 // copper ion binding // non-traceable author statement /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0046870 // cadmium ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR003019 // Metallothionein superfamily, eukaryotic // 4.0E-17 /// IPR003019 // Metallothionein superfamily, eukaryotic // 1.3E-11"
"213664_at",-1.710135329,-1.413747754,-1.5658752,"DOWN","AW235061","chr9:4586152-4587468 (+) // 95.32 // p24.2","solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1","SLC1A1","ENSG00000106688 /// OTTHUMG00000019468","6505","133550 /// 615232","NP_004161","NM_004170","0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006835 // dicarboxylic acid transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0015813 // L-glutamate transport // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051938 // L-glutamate import // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0070779 // D-aspartate import // inferred from direct assay","0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005313 // L-glutamate transmembrane transporter activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015501 // glutamate:sodium symporter activity // inferred from electronic annotation /// 0016595 // glutamate binding // inferred from electronic annotation /// 0017153 // sodium:dicarboxylate symporter activity // inferred from electronic annotation","---","IPR001991 // Sodium:dicarboxylate symporter // 1.3E-137"
"213679_at",-1.752303047,-1.62735001,-1.348010819,"DOWN","AL049329","chr2:178479025-178483124 (-) // 97.02 // q31.2","tetratricopeptide repeat domain 30A","TTC30A","ENSG00000197557 /// OTTHUMG00000132528","92104","---","NP_689488","NM_152275","0030030 // cell projection organization // inferred from electronic annotation","0005929 // cilium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation","0005515 // protein binding // inferred from electronic annotation","---","---"
"213693_s_at",1.351287072,1.452232104,1.725141276,"UP","AI610869","chr1:155158301-155158646 (-) // 92.74 // q22","mucin 1, cell surface associated","MUC1","ENSG00000185499 /// OTTHUMG00000035681","4582","158340 /// 174000","NP_001018016 /// NP_001018017 /// NP_001037855 /// NP_001037856 /// NP_001037857 /// NP_001037858 /// NP_001191214 /// NP_001191215 /// NP_001191216 /// NP_001191217 /// NP_001191218 /// NP_001191219 /// NP_001191220 /// NP_001191221 /// NP_001191222 /// NP_001191223 /// NP_001191224 /// NP_001191225 /// NP_001191226 /// NP_002447","NM_001018016 /// NM_001018017 /// NM_001018021 /// NM_001044390 /// NM_001044391 /// NM_001044392 /// NM_001044393 /// NM_001204285 /// NM_001204286 /// NM_001204287 /// NM_001204288 /// NM_001204289 /// NM_001204290 /// NM_001204291 /// NM_001204292 /// NM_001204293 /// NM_001204294 /// NM_001204295 /// NM_001204296 /// NM_001204297 /// NM_002456 /// NM_182741","0001666 // response to hypoxia // inferred from electronic annotation /// 0006977 // DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest // inferred from direct assay /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from direct assay /// 0007565 // female pregnancy // inferred from electronic annotation /// 0010944 // negative regulation of transcription by competitive promoter binding // inferred from direct assay /// 0016266 // O-glycan processing // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0036003 // positive regulation of transcription from RNA polymerase II promoter in response to stress // inferred from direct assay /// 0043618 // regulation of transcription from RNA polymerase II promoter in response to stress // inferred from direct assay /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0071300 // cellular response to retinoic acid // inferred from electronic annotation /// 0090240 // positive regulation of histone H4 acetylation // inferred from direct assay /// 1902166 // negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator // inferred from direct assay","0000790 // nuclear chromatin // inferred from direct assay /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from direct assay /// 0002039 // p53 binding // inferred from physical interaction /// 0003712 // transcription cofactor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction","---","IPR000082 // SEA domain // 5.3E-24"
"213839_at",-1.488580539,-1.760176395,-1.59909256,"DOWN","AW028110","chr14:95648277-95654806 (-) // 73.18 // q32.13","calmin (calponin-like, transmembrane)","CLMN","ENSG00000165959 /// OTTHUMG00000171629","79789","611121","NP_079010 /// XP_006720319","NM_024734 /// XM_006720256 /// XR_245721 /// XR_245722 /// XR_429330 /// XR_429331 /// XR_429332","0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0031175 // neuron projection development // inferred from electronic annotation","0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation","---","IPR001715 // Calponin homology domain // 6.0E-19 /// IPR001715 // Calponin homology domain // 6.7E-23"
"213920_at",-2.326948492,-2.09616556,-2.45994645,"DOWN","AB006631","chr12:111733150-111788779 (+) // 99.14 // q24.12","cut-like homeobox 2","CUX2","ENSG00000111249 /// OTTHUMG00000169546","23316","610648","NP_056082 /// XP_006719362","NM_015267 /// XM_006719299","0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // non-traceable author statement /// 0007614 // short-term memory // inferred from sequence or structural similarity /// 0010628 // positive regulation of gene expression // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0050775 // positive regulation of dendrite morphogenesis // inferred from sequence or structural similarity /// 0050890 // cognition // inferred from mutant phenotype /// 0051965 // positive regulation of synapse assembly // inferred from sequence or structural similarity /// 0061003 // positive regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 2000463 // positive regulation of excitatory postsynaptic membrane potential // inferred from sequence or structural similarity","0005634 // nucleus // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0000977 // RNA polymerase II regulatory region sequence-specific DNA binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from direct assay","---","IPR001356 // Homeobox domain // 1.7E-16 /// IPR003350 // CUT domain // 2.4E-30 /// IPR003350 // CUT domain // 4.6E-32 /// IPR003350 // CUT domain // 5.3E-32"
"214044_at",-2.448740235,-1.695938062,-2.358696219,"DOWN","BE968750","chr1:237993827-237997288 (+) // 96.84 // q43","ryanodine receptor 2 (cardiac)","RYR2","ENSG00000198626 /// OTTHUMG00000039543","6262","180902 /// 600996 /// 604772","NP_001026 /// XP_006711865 /// XP_006711866 /// XP_006711867 /// XP_006711868 /// XP_006711869 /// XP_006711870 /// XP_006711871 /// XP_006711872 /// XP_006711873","NM_001035 /// XM_006711802 /// XM_006711803 /// XM_006711804 /// XM_006711805 /// XM_006711806 /// XM_006711807 /// XM_006711808 /// XM_006711809 /// XM_006711810","0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0002027 // regulation of heart rate // inferred from mutant phenotype /// 0003143 // embryonic heart tube morphogenesis // inferred from sequence or structural similarity /// 0003220 // left ventricular cardiac muscle tissue morphogenesis // inferred from sequence or structural similarity /// 0003300 // cardiac muscle hypertrophy // inferred from sequence or structural similarity /// 0005513 // detection of calcium ion // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010460 // positive regulation of heart rate // inferred from sequence or structural similarity /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred by curator /// 0010881 // regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion // inferred from sequence or structural similarity /// 0014808 // release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from mutant phenotype /// 0014808 // release of sequestered calcium ion into cytosol by sarcoplasmic reticulum // inferred from sequence or structural similarity /// 0019722 // calcium-mediated signaling // inferred from sequence or structural similarity /// 0030509 // BMP signaling pathway // inferred from electronic annotation /// 0031000 // response to caffeine // inferred from direct assay /// 0034220 // ion transmembrane transport // traceable author statement /// 0035584 // calcium-mediated signaling using intracellular calcium source // inferred from direct assay /// 0051209 // release of sequestered calcium ion into cytosol // inferred from direct assay /// 0051209 // release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0051284 // positive regulation of sequestering of calcium ion // inferred from direct assay /// 0051480 // cytosolic calcium ion homeostasis // inferred from sequence or structural similarity /// 0051775 // response to redox state // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 0055117 // regulation of cardiac muscle contraction // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred from electronic annotation /// 0060401 // cytosolic calcium ion transport // inferred from electronic annotation /// 0060402 // calcium ion transport into cytosol // inferred from direct assay /// 0070296 // sarcoplasmic reticulum calcium ion transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation /// 0071313 // cellular response to caffeine // inferred from direct assay /// 0071313 // cellular response to caffeine // inferred from sequence or structural similarity /// 0071872 // cellular response to epinephrine stimulus // traceable author statement /// 0072599 // establishment of protein localization to endoplasmic reticulum // inferred from direct assay /// 0086005 // ventricular cardiac muscle cell action potential // inferred from sequence or structural similarity /// 0086029 // Purkinje myocyte to ventricular cardiac muscle cell signaling // inferred from sequence or structural similarity /// 0086064 // cell communication by electrical coupling involved in cardiac conduction // inferred by curator /// 0086094 // positive regulation of ryanodine-sensitive calcium-release channel activity by adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction // inferred from sequence or structural similarity /// 0097050 // type B pancreatic cell apoptotic process // inferred from mutant phenotype /// 1901896 // positive regulation of calcium-transporting ATPase activity // inferred from direct assay","0005886 // plasma membrane // inferred from sequence or structural similarity /// 0014701 // junctional sarcoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from direct assay /// 0030017 // sarcomere // inferred from electronic annotation /// 0030018 // Z disc // inferred from sequence or structural similarity /// 0033017 // sarcoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0033017 // sarcoplasmic reticulum membrane // traceable author statement /// 0034704 // calcium channel complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005216 // ion channel activity // inferred from electronic annotation /// 0005218 // intracellular ligand-gated calcium channel activity // inferred from sequence or structural similarity /// 0005219 // ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0005262 // calcium channel activity // inferred from sequence or structural similarity /// 0005488 // binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from mutant phenotype /// 0005516 // calmodulin binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from sequence or structural similarity /// 0015278 // calcium-release channel activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0034236 // protein kinase A catalytic subunit binding // inferred from direct assay /// 0034237 // protein kinase A regulatory subunit binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0043621 // protein self-association // inferred from electronic annotation /// 0043924 // suramin binding // inferred from mutant phenotype /// 0044325 // ion channel binding // inferred from sequence or structural similarity /// 0048763 // calcium-induced calcium release activity // inferred from direct assay","Calcium_regulation_in_cardiac_cells // GenMAPP /// Smooth_muscle_contraction // GenMAPP","IPR000699 // RIH (RyR and IP3R Homology) domain // 2.4E-73 /// IPR000699 // RIH (RyR and IP3R Homology) domain // 3.4E-65 /// IPR003032 // Ryanodine receptor Ryr // 5.5E-34 /// IPR003032 // Ryanodine receptor Ryr // 1.4E-33 /// IPR003032 // Ryanodine receptor Ryr // 1.1E-37 /// IPR003032 // Ryanodine receptor Ryr // 2.9E-34 /// IPR003877 // SPRY domain // 1.2E-28 /// IPR003877 // SPRY domain // 1.7E-31 /// IPR003877 // SPRY domain // 5.9E-25 /// IPR005821 // Ion transport domain // 5.0E-12 /// IPR009460 // Ryanodine Receptor TM 4-6 // 1.3E-91 /// IPR013662 // RyR/IP3R Homology associated domain // 1.2E-40 /// IPR014821 // Inositol 1,4,5-trisphosphate/ryanodine receptor // 1.4E-75 /// IPR016093 // MIR motif // 1.0E-53"
"214053_at",-1.206891531,-1.051594233,-1.848846595,"DOWN","AW772192","chr2:212240445-212242243 (-) // 94.99 // q34","v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4","ERBB4","ENSG00000178568 /// OTTHUMG00000133012","2066","600543 /// 615515","NP_001036064 /// NP_005226 /// XP_005246432 /// XP_005246433 /// XP_005246434 /// XP_006712427","NM_001042599 /// NM_005235 /// XM_005246375 /// XM_005246376 /// XM_005246377 /// XM_006712364","0001755 // neural crest cell migration // inferred from sequence or structural similarity /// 0001934 // positive regulation of protein phosphorylation // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from direct assay /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from sequence or structural similarity /// 0007507 // heart development // inferred from sequence or structural similarity /// 0007595 // lactation // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009880 // embryonic pattern specification // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0021551 // central nervous system morphogenesis // inferred from sequence or structural similarity /// 0021889 // olfactory bulb interneuron differentiation // inferred from sequence or structural similarity /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from sequence or structural similarity /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042523 // positive regulation of tyrosine phosphorylation of Stat5 protein // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from direct assay /// 0043653 // mitochondrial fragmentation involved in apoptotic process // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from sequence or structural similarity /// 0060644 // mammary gland epithelial cell differentiation // inferred from sequence or structural similarity /// 0060749 // mammary gland alveolus development // inferred from sequence or structural similarity /// 0061026 // cardiac muscle tissue regeneration // inferred from sequence or structural similarity /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from mutant phenotype /// 2000366 // positive regulation of STAT protein import into nucleus // inferred from mutant phenotype","0005576 // extracellular region // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0043235 // receptor complex // inferred from direct assay","0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from direct assay /// 0004716 // receptor signaling protein tyrosine kinase activity // inferred from electronic annotation /// 0005154 // epidermal growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044212 // transcription regulatory region DNA binding // inferred from mutant phenotype","---","IPR000494 // EGF receptor, L domain // 1.6E-35 /// IPR000494 // EGF receptor, L domain // 4.9E-30 /// IPR000494 // EGF receptor, L domain // 1.5E-35 /// IPR000494 // EGF receptor, L domain // 4.8E-30 /// IPR000719 // Protein kinase domain // 1.4E-44 /// IPR000719 // Protein kinase domain // 1.3E-44 /// IPR000719 // Protein kinase domain // 1.4E-44 /// IPR001245 // Serine-threonine/tyrosine-protein kinase catalytic domain // 1.8E-94 /// IPR001245 // Serine-threonine/tyrosine-protein kinase catalytic domain // 1.8E-94 /// IPR006211 // Furin-like cysteine-rich domain // 1.2E-32"
"214162_at",-1.781741592,-1.200530515,-2.111373962,"DOWN","AF070541","chr18:31329599-31331156 (+) // 98.73 // q12.1","additional sex combs like transcriptional regulator 3","ASXL3","ENSG00000141431 /// OTTHUMG00000178395","80816","615115 /// 615485","NP_085135 /// XP_005258413","NM_030632 /// XM_005258356","0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation","0005634 // nucleus // inferred from electronic annotation","0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","---"
"214175_x_at",1.973216565,2.681805542,2.515700147,"UP","AI254547","chr5:131607869-131608025 (+) // 64.73 // q31.1","PDZ and LIM domain 4","PDLIM4","ENSG00000131435 /// OTTHUMG00000059645","8572","166710 /// 603422","NP_001124499 /// NP_003678 /// XP_006714786","NM_001131027 /// NM_003687 /// XM_006714723","---","---","0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR001478 // PDZ domain // 1.8E-19 /// IPR001478 // PDZ domain // 5.2E-20 /// IPR001781 // Zinc finger, LIM-type // 6.3E-19"
"214307_at",-2.169765201,-1.311587419,-1.715182075,"DOWN","AI478172","chr3:120352179-120360643 (-) // 84.57 // q13.33","homogentisate 1,2-dioxygenase","HGD","ENSG00000113924 /// OTTHUMG00000159441","3081","203500 /// 607474","NP_000178 /// XP_005247469 /// XP_005247470 /// XP_005247471","NM_000187 /// XM_005247412 /// XM_005247413 /// XM_005247414","0006520 // cellular amino acid metabolic process // inferred from electronic annotation /// 0006559 // L-phenylalanine catabolic process // inferred from electronic annotation /// 0006559 // L-phenylalanine catabolic process // traceable author statement /// 0006570 // tyrosine metabolic process // inferred from electronic annotation /// 0006572 // tyrosine catabolic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation","0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0004411 // homogentisate 1,2-dioxygenase activity // not recorded /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051213 // dioxygenase activity // inferred from electronic annotation","---","IPR005708 // Homogentisate 1,2-dioxygenase // 5.9E-78"
"214354_x_at",1.572845294,1.546419675,2.601477319,"UP","T91506","chr2:85884804-85885613 (-) // 40.73 // p11.2","surfactant protein B","SFTPB","ENSG00000168878 /// OTTHUMG00000130181","6439","178640 /// 265120","NP_000533 /// NP_942140 /// XP_005264544 /// XP_005264545 /// XP_005264546 /// XP_005264547 /// XP_006712139","NM_000542 /// NM_198843 /// XM_005264487 /// XM_005264488 /// XM_005264489 /// XM_005264490 /// XM_006712076","0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement","0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation","---","---","IPR003119 // Saposin type A // 1.7E-18 /// IPR003119 // Saposin type A // 1.8E-18 /// IPR007856 // Saposin-like type B, 1 // 3.8E-9 /// IPR007856 // Saposin-like type B, 1 // 4.0E-9 /// IPR008138 // Saposin-like type B, 2 // 5.7E-14 /// IPR008138 // Saposin-like type B, 2 // 6.1E-8 /// IPR008138 // Saposin-like type B, 2 // 2.7E-14 /// IPR008138 // Saposin-like type B, 2 // 6.0E-14 /// IPR008138 // Saposin-like type B, 2 // 6.3E-8 /// IPR008138 // Saposin-like type B, 2 // 2.8E-14"
"214414_x_at",-1.248008533,-1.200071149,-1.991479507,"DOWN","T50399","chr16:223221-223705 (+) // 92.35 // p13.3","hemoglobin, alpha 1 /// hemoglobin, alpha 2","HBA1 /// HBA2","ENSG00000188536 /// OTTHUMG00000059924","3039 /// 3040","140700 /// 141800 /// 141850 /// 604131 /// 613978","NP_000508 /// NP_000549","NM_000517 /// NM_000558","0006810 // transport // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0015671 // oxygen transport // traceable author statement /// 0015701 // bicarbonate transport // traceable author statement /// 0042542 // response to hydrogen peroxide // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay","0005576 // extracellular region // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005833 // hemoglobin complex // inferred from direct assay /// 0005833 // hemoglobin complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0031838 // haptoglobin-hemoglobin complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay","0004601 // peroxidase activity // inferred from direct assay /// 0005344 // oxygen transporter activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019825 // oxygen binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0031720 // haptoglobin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000971 // Globin // 2.9E-32 /// IPR000971 // Globin // 3.1E-23"
"214433_s_at",-1.595409662,-1.057748185,-1.39607933,"DOWN","NM_003944","chr1:151336796-151345191 (-) // 98.5 // q21.3","selenium binding protein 1","SELENBP1","ENSG00000143416 /// OTTHUMG00000012498","8991","604188","NP_001245217 /// NP_001245218 /// NP_003935","NM_001258288 /// NM_001258289 /// NM_003944","0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation","0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005515 // protein binding // inferred from physical interaction /// 0008430 // selenium binding // inferred from electronic annotation","---","IPR008826 // Selenium-binding protein // 1.1E-223 /// IPR008826 // Selenium-binding protein // 2.3E-22 /// IPR008826 // Selenium-binding protein // 9.3E-165 /// IPR008826 // Selenium-binding protein // 1.6E-223 /// IPR008826 // Selenium-binding protein // 3.6E-56 /// IPR008826 // Selenium-binding protein // 9.9E-56"
"214702_at",2.912232171,2.484270557,3.36576198,"UP","AJ276395","chr2:216279383-216300652 (-) // 98.51 // q35","fibronectin 1","FN1","ENSG00000115414 /// OTTHUMG00000133054","2335","135600 /// 601894 /// 614101","NP_002017 /// NP_473375 /// NP_997639 /// NP_997641 /// NP_997643 /// NP_997647 /// XP_005246454 /// XP_005246455 /// XP_005246456 /// XP_005246457 /// XP_005246458 /// XP_005246459 /// XP_005246460 /// XP_005246461 /// XP_005246462 /// XP_005246463 /// XP_005246464 /// XP_005246465 /// XP_005246466 /// XP_005246467 /// XP_005246468 /// XP_005246469 /// XP_005246470 /// XP_005246471 /// XP_005246472 /// XP_005246473 /// XP_005246474","NM_002026 /// NM_054034 /// NM_212474 /// NM_212475 /// NM_212476 /// NM_212478 /// NM_212482 /// XM_005246397 /// XM_005246398 /// XM_005246399 /// XM_005246400 /// XM_005246401 /// XM_005246402 /// XM_005246403 /// XM_005246404 /// XM_005246405 /// XM_005246406 /// XM_005246407 /// XM_005246408 /// XM_005246409 /// XM_005246410 /// XM_005246411 /// XM_005246412 /// XM_005246413 /// XM_005246414 /// XM_005246415 /// XM_005246416 /// XM_005246417","0001525 // angiogenesis // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007044 // cell-substrate junction assembly // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007161 // calcium-independent cell-matrix adhesion // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009611 // response to wounding // non-traceable author statement /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0018149 // peptide cross-linking // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0042060 // wound healing // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement","0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay","0002020 // protease binding // inferred from physical interaction /// 0005178 // integrin binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // non-traceable author statement /// 0008201 // heparin binding // non-traceable author statement /// 0016504 // peptidase activator activity // inferred from electronic annotation","Inflammatory_Response_Pathway // GenMAPP","IPR000083 // Fibronectin, type I // 1.9E-15 /// IPR000083 // Fibronectin, type I // 2.7E-19 /// IPR000083 // Fibronectin, type I // 1.6E-17 /// IPR000083 // Fibronectin, type I // 1.2E-19 /// IPR000083 // Fibronectin, type I // 3.4E-19 /// IPR000083 // Fibronectin, type I // 1.8E-13 /// IPR000083 // Fibronectin, type I // 1.5E-19 /// IPR000083 // Fibronectin, type I // 4.0E-17 /// IPR000083 // Fibronectin, type I // 5.2E-19 /// IPR000562 // Fibronectin, type II, collagen-binding // 1.1E-22 /// IPR000562 // Fibronectin, type II, collagen-binding // 6.4E-22"
"214735_at",-3.409106434,-2.901484771,-3.475961682,"DOWN","AW166711","chr6:154475633-154567896 (-) // 93.21 // q25.2","interaction protein for cytohesin exchange factors 1","IPCEF1","---","26034","---","NP_001124171 /// NP_001124172 /// NP_056368 /// XP_005266976 /// XP_005266977 /// XP_005266978 /// XP_005266979 /// XP_005266980","NM_001130699 /// NM_001130700 /// NM_015553 /// XM_005266919 /// XM_005266920 /// XM_005266921 /// XM_005266922 /// XM_005266923","0006979 // response to oxidative stress // inferred from sequence or structural similarity /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0015671 // oxygen transport // non-traceable author statement /// 0055114 // oxidation-reduction process // inferred from sequence or structural similarity","0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation","0004601 // peroxidase activity // inferred from sequence or structural similarity /// 0005344 // oxygen transporter activity // non-traceable author statement","---","---"
"214745_at",-1.7401396,-1.319625498,-1.939094105,"DOWN","AW665865","chr3:155197670-155301350 (-) // 99.75 // q25.31","phospholipase C, eta 1","PLCH1","ENSG00000114805 /// OTTHUMG00000158477","23007","612835","NP_001124432 /// NP_001124433 /// NP_055811 /// XP_005247295 /// XP_005247296 /// XP_006713604","NM_001130960 /// NM_001130961 /// NM_014996 /// XM_005247238 /// XM_005247239 /// XM_006713541","0006629 // lipid metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // inferred from direct assay","0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay","0004435 // phosphatidylinositol phospholipase C activity // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050429 // calcium-dependent phospholipase C activity // inferred from direct assay","---","IPR000008 // C2 domain // 2.9E-19 /// IPR000008 // C2 domain // 1.6E-19 /// IPR000008 // C2 domain // 3.0E-19 /// IPR000909 // Phospholipase C, phosphatidylinositol-specific , X domain // 1.5E-65 /// IPR000909 // Phospholipase C, phosphatidylinositol-specific , X domain // 7.8E-66 /// IPR000909 // Phospholipase C, phosphatidylinositol-specific , X domain // 1.6E-65 /// IPR001711 // Phospholipase C, phosphatidylinositol-specific, Y domain // 2.5E-45 /// IPR001711 // Phospholipase C, phosphatidylinositol-specific, Y domain // 1.3E-45 /// IPR001711 // Phospholipase C, phosphatidylinositol-specific, Y domain // 2.6E-45 /// IPR015359 // Phospholipase C, phosphoinositol-specific, EF-hand-like // 3.1E-27 /// IPR015359 // Phospholipase C, phosphoinositol-specific, EF-hand-like // 1.7E-27 /// IPR015359 // Phospholipase C, phosphoinositol-specific, EF-hand-like // 3.2E-27"
"214803_at",2.782753356,1.245548589,1.572410836,"UP","BF344237","chr5:31326799-31329251 (+) // 90.41 // p13.3","cadherin 6, type 2, K-cadherin (fetal kidney)","CDH6","ENSG00000113361 /// OTTHUMG00000090673","1004","603007","NP_004923","NM_004932","0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0034329 // cell junction assembly // traceable author statement /// 0034332 // adherens junction organization // traceable author statement /// 0045216 // cell-cell junction organization // traceable author statement","0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000233 // Cadherin, cytoplasmic domain // 1.2E-61 /// IPR002126 // Cadherin // 8.3E-13 /// IPR002126 // Cadherin // 1.3E-22 /// IPR002126 // Cadherin // 4.1E-19 /// IPR002126 // Cadherin // 7.4E-18 /// IPR002126 // Cadherin // 8.7E-14"
"214977_at",-1.449322451,-1.192937931,-1.890356393,"DOWN","AK023852","chr8:134079862-134082264 (+) // 43.08 // q24.22","---","---","---","---","---","---","---","---","---","---","---","---"
"215380_s_at",1.273527891,1.519919352,1.755112534,"UP","AK021779","chr7:30536238-30540064 (-) // 76.28 // p14.3","gamma-glutamylcyclotransferase","GGCT","ENSG00000006625 /// OTTHUMG00000128593","79017","137170","NP_001186744 /// NP_001186745 /// NP_001186746 /// NP_076956","NM_001199815 /// NM_001199816 /// NM_001199817 /// NM_024051 /// NR_037669","0001836 // release of cytochrome c from mitochondria // inferred from mutant phenotype /// 0006750 // glutathione biosynthetic process // traceable author statement /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 1901687 // glutathione derivative biosynthetic process // traceable author statement","0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0003839 // gamma-glutamylcyclotransferase activity // inferred from direct assay /// 0003839 // gamma-glutamylcyclotransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay","---","IPR009288 // AIG2-like // 1.8E-11 /// IPR009288 // AIG2-like // 2.5E-11"
"215536_at",1.295498483,1.617515539,1.750986,"UP","X87344","chr6:32723896-32731306 (-) // 98.66 // p21.32","major histocompatibility complex, class II, DQ beta 2","HLA-DQB2","ENSG00000224305 /// ENSG00000226165 /// ENSG00000230675 /// ENSG00000232629 /// OTTHUMG00000031125 /// OTTHUMG00000031405 /// OTTHUMG00000140120 /// OTTHUMG00000148825","3120","615161","NP_001185787 /// XP_005249108 /// XP_005272864 /// XP_005274912 /// XP_005275603","NM_001198858 /// NM_182549 /// NR_003937 /// XM_005249051 /// XM_005272807 /// XM_005274855 /// XM_005275546","0002376 // immune system process // inferred from electronic annotation /// 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0031295 // T cell costimulation // traceable author statement /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement","0000139 // Golgi membrane // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0012507 // ER to Golgi transport vesicle membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030658 // transport vesicle membrane // traceable author statement /// 0030666 // endocytic vesicle membrane // traceable author statement /// 0030669 // clathrin-coated endocytic vesicle membrane // traceable author statement /// 0032588 // trans-Golgi network membrane // traceable author statement /// 0042613 // MHC class II protein complex // non-traceable author statement /// 0071556 // integral component of lumenal side of endoplasmic reticulum membrane // traceable author statement","0005515 // protein binding // inferred from electronic annotation /// 0032395 // MHC class II receptor activity // non-traceable author statement","---","IPR000353 // MHC class II, beta chain, N-terminal // 2.4E-37 /// IPR000353 // MHC class II, beta chain, N-terminal // 2.5E-37 /// IPR000353 // MHC class II, beta chain, N-terminal // 1.8E-37 /// IPR003597 // Immunoglobulin C1-set // 1.0E-33 /// IPR003597 // Immunoglobulin C1-set // 1.1E-33 /// IPR003597 // Immunoglobulin C1-set // 7.5E-34 /// IPR013162 // CD80-like, immunoglobulin C2-set // 2.4E-9 /// IPR013162 // CD80-like, immunoglobulin C2-set // 2.6E-9 /// IPR013162 // CD80-like, immunoglobulin C2-set // 1.7E-9"
"215692_s_at",-2.064754333,-2.323420448,-1.004546165,"DOWN","BE645386","chr11:30601752-30605561 (-) // 99.28 // p14.1","metallophosphoesterase domain containing 2","MPPED2","ENSG00000066382 /// OTTHUMG00000166159","744","600911","NP_001138871 /// NP_001575 /// XP_005253167 /// XP_005253168 /// XP_005253169 /// XP_005253170 /// XP_005253171 /// XP_006718367 /// XP_006718368","NM_001145399 /// NM_001584 /// XM_005253110 /// XM_005253111 /// XM_005253112 /// XM_005253113 /// XM_005253114 /// XM_006718304 /// XM_006718305","0007399 // nervous system development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation","---","0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR004843 // Calcineurin-like phosphoesterase domain, apaH type // 6.1E-12 /// IPR004843 // Calcineurin-like phosphoesterase domain, apaH type // 6.1E-12"
"216442_x_at",3.035975993,2.585949574,2.669055788,"UP","AK026737","chr2:216225588-216227767 (-) // 67.89 // q35","fibronectin 1","FN1","ENSG00000115414 /// OTTHUMG00000133054","2335","135600 /// 601894 /// 614101","NP_002017 /// NP_473375 /// NP_997639 /// NP_997641 /// NP_997643 /// NP_997647 /// XP_005246454 /// XP_005246455 /// XP_005246456 /// XP_005246457 /// XP_005246458 /// XP_005246459 /// XP_005246460 /// XP_005246461 /// XP_005246462 /// XP_005246463 /// XP_005246464 /// XP_005246465 /// XP_005246466 /// XP_005246467 /// XP_005246468 /// XP_005246469 /// XP_005246470 /// XP_005246471 /// XP_005246472 /// XP_005246473 /// XP_005246474","NM_002026 /// NM_054034 /// NM_212474 /// NM_212475 /// NM_212476 /// NM_212478 /// NM_212482 /// XM_005246397 /// XM_005246398 /// XM_005246399 /// XM_005246400 /// XM_005246401 /// XM_005246402 /// XM_005246403 /// XM_005246404 /// XM_005246405 /// XM_005246406 /// XM_005246407 /// XM_005246408 /// XM_005246409 /// XM_005246410 /// XM_005246411 /// XM_005246412 /// XM_005246413 /// XM_005246414 /// XM_005246415 /// XM_005246416 /// XM_005246417","0001525 // angiogenesis // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0007044 // cell-substrate junction assembly // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007161 // calcium-independent cell-matrix adhesion // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009611 // response to wounding // non-traceable author statement /// 0010952 // positive regulation of peptidase activity // inferred from electronic annotation /// 0016477 // cell migration // non-traceable author statement /// 0018149 // peptide cross-linking // inferred from direct assay /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0042060 // wound healing // inferred from electronic annotation /// 0050900 // leukocyte migration // traceable author statement","0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0072562 // blood microparticle // inferred from direct assay","0002020 // protease binding // inferred from physical interaction /// 0005178 // integrin binding // inferred from direct assay /// 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // non-traceable author statement /// 0008201 // heparin binding // non-traceable author statement /// 0016504 // peptidase activator activity // inferred from electronic annotation","Inflammatory_Response_Pathway // GenMAPP","IPR000083 // Fibronectin, type I // 2.0E-14 /// IPR000083 // Fibronectin, type I // 2.7E-18 /// IPR000083 // Fibronectin, type I // 1.6E-16 /// IPR000083 // Fibronectin, type I // 1.2E-18 /// IPR000083 // Fibronectin, type I // 3.5E-18 /// IPR000083 // Fibronectin, type I // 1.8E-12 /// IPR000083 // Fibronectin, type I // 1.5E-18 /// IPR000083 // Fibronectin, type I // 4.0E-16 /// IPR000083 // Fibronectin, type I // 5.3E-18 /// IPR000083 // Fibronectin, type I // 1.2E-18 /// IPR000083 // Fibronectin, type I // 8.3E-17 /// IPR000083 // Fibronectin, type I // 1.5E-13 /// IPR000083 // Fibronectin, type I // 2.2E-14 /// IPR000083 // Fibronectin, type I // 3.0E-18 /// IPR000083 // Fibronectin, type I // 1.8E-16 /// IPR000083 // Fibronectin, type I // 1.3E-18 /// IPR000083 // Fibronectin, type I // 3.9E-18 /// IPR000083 // Fibronectin, type I // 2.0E-12 /// IPR000083 // Fibronectin, type I // 1.6E-18 /// IPR000083 // Fibronectin, type I // 4.4E-16 /// IPR000083 // Fibronectin, type I // 5.9E-18 /// IPR000083 // Fibronectin, type I // 1.3E-18 /// IPR000083 // Fibronectin, type I // 9.2E-17 /// IPR000083 // Fibronectin, type I // 1.7E-13 /// IPR000083 // Fibronectin, type I // 2.1E-14 /// IPR000083 // Fibronectin, type I // 2.9E-18 /// IPR000083 // Fibronectin, type I // 1.7E-16 /// IPR000083 // Fibronectin, type I // 3.7E-18 /// IPR000083 // Fibronectin, type I // 4.3E-16 /// IPR000083 // Fibronectin, type I // 5.6E-18 /// IPR000083 // Fibronectin, type I // 1.3E-18 /// IPR000083 // Fibronectin, type I // 8.8E-17 /// IPR000083 // Fibronectin, type I // 1.6E-13 /// IPR000083 // Fibronectin, type I // 1.9E-14 /// IPR000083 // Fibronectin, type I // 2.6E-18 /// IPR000083 // Fibronectin, type I // 3.4E-18 /// IPR000083 // Fibronectin, type I // 1.4E-18 /// IPR000083 // Fibronectin, type I // 3.9E-16 /// IPR000083 // Fibronectin, type I // 5.2E-18 /// IPR000083 // Fibronectin, type I // 1.2E-18 /// IPR000083 // Fibronectin, type I // 8.1E-17 /// IPR000083 // Fibronectin, type I // 1.5E-13 /// IPR000083 // Fibronectin, type I // 1.4E-18 /// IPR000083 // Fibronectin, type I // 2.1E-12 /// IPR000083 // Fibronectin, type I // 1.7E-18 /// IPR000083 // Fibronectin, type I // 4.5E-16 /// IPR000083 // Fibronectin, type I // 1.4E-18 /// IPR000083 // Fibronectin, type I // 9.3E-17 /// IPR000083 // Fibronectin, type I // 1.7E-13 /// IPR000083 // Fibronectin, type I // 2.8E-18 /// IPR000083 // Fibronectin, type I // 1.9E-12 /// IPR000083 // Fibronectin, type I // 4.2E-16 /// IPR000083 // Fibronectin, type I // 1.3E-18 /// IPR000083 // Fibronectin, type I // 8.7E-17 /// IPR000083 // Fibronectin, type I // 1.6E-13 /// IPR000083 // Fibronectin, type I // 3.6E-18 /// IPR000083 // Fibronectin, type I // 4.1E-16 /// IPR000083 // Fibronectin, type I // 5.4E-18 /// IPR000083 // Fibronectin, type I // 1.2E-18 /// IPR000083 // Fibronectin, type I // 8.4E-17 /// IPR000083 // Fibronectin, type I // 1.5E-13 /// IPR000083 // Fibronectin, type I // 1.2E-18 /// IPR000083 // Fibronectin, type I // 8.4E-17 /// IPR000083 // Fibronectin, type I // 1.5E-13 /// IPR000083 // Fibronectin, type I // 5.5E-18 /// IPR000083 // Fibronectin, type I // 1.3E-18 /// IPR000083 // Fibronectin, type I // 8.6E-17 /// IPR000083 // Fibronectin, type I // 1.5E-13 /// IPR000083 // Fibronectin, type I // 3.8E-18 /// IPR000083 // Fibronectin, type I // 5.7E-18 /// IPR000083 // Fibronectin, type I // 1.3E-18 /// IPR000083 // Fibronectin, type I // 8.9E-17 /// IPR000083 // Fibronectin, type I // 1.6E-13 /// IPR000562 // Fibronectin, type II, collagen-binding // 1.1E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 6.5E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 1.2E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 7.2E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 6.9E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 6.3E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 7.3E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 6.8E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 6.6E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 6.7E-21 /// IPR000562 // Fibronectin, type II, collagen-binding // 7.0E-21 /// IPR003961 // Fibronectin, type III // 2.3E-15 /// IPR003961 // Fibronectin, type III // 5.2E-16 /// IPR003961 // Fibronectin, type III // 8.3E-22 /// IPR003961 // Fibronectin, type III // 2.1E-18 /// IPR003961 // Fibronectin, type III // 6.6E-19 /// IPR003961 // Fibronectin, type III // 6.0E-10 /// IPR003961 // Fibronectin, type III // 1.3E-16 /// IPR003961 // Fibronectin, type III // 3.7E-20 /// IPR003961 // Fibronectin, type III // 6.0E-20 /// IPR003961 // Fibronectin, type III // 4.9E-24 /// IPR003961 // Fibronectin, type III // 1.0E-20 /// IPR003961 // Fibronectin, type III // 1.1E-19 /// IPR003961 // Fibronectin, type III // 1.3E-18 /// IPR003961 // Fibronectin, type III // 4.0E-21 /// IPR003961 // Fibronectin, type III // 5.8E-11 /// IPR003961 // Fibronectin, type III // 2.5E-15 /// IPR003961 // Fibronectin, type III // 5.7E-16 /// IPR003961 // Fibronectin, type III // 9.1E-22 /// IPR003961 // Fibronectin, type III // 2.4E-18 /// IPR003961 // Fibronectin, type III // 7.3E-19 /// IPR003961 // Fibronectin, type III // 6.6E-10 /// IPR003961 // Fibronectin, type III // 1.4E-16 /// IPR003961 // Fibronectin, type III // 8.1E-16 /// IPR003961 // Fibronectin, type III // 4.1E-20 /// IPR003961 // Fibronectin, type III // 6.6E-20 /// IPR003961 // Fibronectin, type III // 5.4E-24 /// IPR003961 // Fibronectin, type III // 1.1E-20 /// IPR003961 // Fibronectin, type III // 1.1E-15 /// IPR003961 // Fibronectin, type III // 1.3E-19 /// IPR003961 // Fibronectin, type III // 1.4E-18 /// IPR003961 // Fibronectin, type III // 4.4E-21 /// IPR003961 // Fibronectin, type III // 6.4E-11 /// IPR003961 // Fibronectin, type III // 2.4E-15 /// IPR003961 // Fibronectin, type III // 5.5E-16 /// IPR003961 // Fibronectin, type III // 8.7E-22 /// IPR003961 // Fibronectin, type III // 2.3E-18 /// IPR003961 // Fibronectin, type III // 7.0E-19 /// IPR003961 // Fibronectin, type III // 6.3E-10 /// IPR003961 // Fibronectin, type III // 3.9E-20 /// IPR003961 // Fibronectin, type III // 6.4E-20 /// IPR003961 // Fibronectin, type III // 5.2E-24 /// IPR003961 // Fibronectin, type III // 1.1E-20 /// IPR003961 // Fibronectin, type III // 1.1E-15 /// IPR003961 // Fibronectin, type III // 1.2E-19 /// IPR003961 // Fibronectin, type III // 1.3E-18 /// IPR003961 // Fibronectin, type III // 4.2E-21 /// IPR003961 // Fibronectin, type III // 6.1E-11 /// IPR003961 // Fibronectin, type III // 2.2E-15 /// IPR003961 // Fibronectin, type III // 5.0E-16 /// IPR003961 // Fibronectin, type III // 8.0E-22 /// IPR003961 // Fibronectin, type III // 6.4E-19 /// IPR003961 // Fibronectin, type III // 5.8E-10 /// IPR003961 // Fibronectin, type III // 1.2E-16 /// IPR003961 // Fibronectin, type III // 3.6E-20 /// IPR003961 // Fibronectin, type III // 5.8E-20 /// IPR003961 // Fibronectin, type III // 4.7E-24 /// IPR003961 // Fibronectin, type III // 9.9E-21 /// IPR003961 // Fibronectin, type III // 1.2E-18 /// IPR003961 // Fibronectin, type III // 3.9E-21 /// IPR003961 // Fibronectin, type III // 8.4E-11 /// IPR003961 // Fibronectin, type III // 2.6E-15 /// IPR003961 // Fibronectin, type III // 5.8E-16 /// IPR003961 // Fibronectin, type III // 9.3E-22 /// IPR003961 // Fibronectin, type III // 7.4E-19 /// IPR003961 // Fibronectin, type III // 6.7E-10 /// IPR003961 // Fibronectin, type III // 8.3E-16 /// IPR003961 // Fibronectin, type III // 6.7E-20 /// IPR003961 // Fibronectin, type III // 5.5E-24 /// IPR003961 // Fibronectin, type III // 1.2E-20 /// IPR003961 // Fibronectin, type III // 1.2E-15 /// IPR003961 // Fibronectin, type III // 4.5E-21 /// IPR003961 // Fibronectin, type III // 9.0E-11 /// IPR003961 // Fibronectin, type III // 5.4E-16 /// IPR003961 // Fibronectin, type III // 8.6E-22 /// IPR003961 // Fibronectin, type III // 2.2E-18 /// IPR003961 // Fibronectin, type III // 6.9E-19 /// IPR003961 // Fibronectin, type III // 6.2E-10 /// IPR003961 // Fibronectin, type III // 6.3E-20 /// IPR003961 // Fibronectin, type III // 5.1E-24 /// IPR003961 // Fibronectin, type III // 6.0E-11 /// IPR003961 // Fibronectin, type III // 5.3E-16 /// IPR003961 // Fibronectin, type III // 8.4E-22 /// IPR003961 // Fibronectin, type III // 6.7E-19 /// IPR003961 // Fibronectin, type III // 6.1E-10 /// IPR003961 // Fibronectin, type III // 6.1E-20 /// IPR003961 // Fibronectin, type III // 1.2E-19 /// IPR003961 // Fibronectin, type III // 5.8E-11 /// IPR003961 // Fibronectin, type III // 7.5E-16 /// IPR003961 // Fibronectin, type III // 3.7E-20 /// IPR003961 // Fibronectin, type III // 6.1E-20 /// IPR003961 // Fibronectin, type III // 4.9E-24 /// IPR003961 // Fibronectin, type III // 1.0E-20 /// IPR003961 // Fibronectin, type III // 1.2E-19 /// IPR003961 // Fibronectin, type III // 1.3E-18 /// IPR003961 // Fibronectin, type III // 4.0E-21 /// IPR003961 // Fibronectin, type III // 8.8E-11 /// IPR003961 // Fibronectin, type III // 8.5E-22 /// IPR003961 // Fibronectin, type III // 6.8E-19 /// IPR003961 // Fibronectin, type III // 3.8E-20 /// IPR003961 // Fibronectin, type III // 6.2E-20 /// IPR003961 // Fibronectin, type III // 5.0E-24 /// IPR003961 // Fibronectin, type III // 4.1E-21 /// IPR003961 // Fibronectin, type III // 8.3E-11 /// IPR003961 // Fibronectin, type III // 5.6E-16 /// IPR003961 // Fibronectin, type III // 8.9E-22 /// IPR003961 // Fibronectin, type III // 7.1E-19 /// IPR003961 // Fibronectin, type III // 6.4E-10 /// IPR003961 // Fibronectin, type III // 4.0E-20 /// IPR003961 // Fibronectin, type III // 6.5E-20 /// IPR003961 // Fibronectin, type III // 1.4E-18 /// IPR003961 // Fibronectin, type III // 4.3E-21 /// IPR003961 // Fibronectin, type III // 8.7E-11"
"216594_x_at",-1.342115539,-1.061036793,-1.39183598,"DOWN","S68290","chr10:5005645-5260827 (+) // 94.3 // p15.1","aldo-keto reductase family 1, member C1","AKR1C1","---","1645","600449","NP_001344","NM_001353","0001523 // retinoid metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006693 // prostaglandin metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from direct assay /// 0007586 // digestion // inferred from direct assay /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // inferred from direct assay /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008206 // bile acid metabolic process // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0015721 // bile acid and bile salt transport // traceable author statement /// 0030299 // intestinal cholesterol absorption // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from direct assay /// 0034694 // response to prostaglandin // inferred from direct assay /// 0042448 // progesterone metabolic process // inferred from direct assay /// 0042574 // retinal metabolic process // inferred from direct assay /// 0042632 // cholesterol homeostasis // traceable author statement /// 0044597 // daunorubicin metabolic process // inferred from mutant phenotype /// 0044598 // doxorubicin metabolic process // inferred from mutant phenotype /// 0046683 // response to organophosphorus // inferred from expression pattern /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0071395 // cellular response to jasmonic acid stimulus // inferred from direct assay","0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0004032 // alditol:NADP+ 1-oxidoreductase activity // inferred from direct assay /// 0004033 // aldo-keto reductase (NADP) activity // traceable author statement /// 0004958 // prostaglandin F receptor activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016655 // oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor // inferred from direct assay /// 0018636 // phenanthrene 9,10-monooxygenase activity // inferred from direct assay /// 0031406 // carboxylic acid binding // inferred from direct assay /// 0032052 // bile acid binding // inferred from direct assay /// 0047006 // 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity // inferred from electronic annotation /// 0047042 // androsterone dehydrogenase (B-specific) activity // inferred from direct assay /// 0047086 // ketosteroid monooxygenase activity // inferred from direct assay /// 0047115 // trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity // inferred from direct assay /// 0047718 // indanol dehydrogenase activity // inferred from electronic annotation","---","---"
"216733_s_at",-2.183376331,-1.635840916,-1.162381292,"DOWN","X86401","chr15:45653704-45668977 (-) // 75.48 // q21.1","glycine amidinotransferase (L-arginine:glycine amidinotransferase)","GATM","ENSG00000171766 /// OTTHUMG00000131427","2628","602360 /// 612718","NP_001473","NM_001482 /// XR_424635 /// XR_429525 /// XR_433091","0006600 // creatine metabolic process // traceable author statement /// 0006601 // creatine biosynthetic process // inferred from direct assay /// 0006601 // creatine biosynthetic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042246 // tissue regeneration // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046689 // response to mercury ion // inferred from electronic annotation","0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from direct assay /// 0005758 // mitochondrial intermembrane space // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0015067 // amidinotransferase activity // inferred from electronic annotation /// 0015068 // glycine amidinotransferase activity // inferred from direct assay /// 0015068 // glycine amidinotransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016813 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines // inferred from electronic annotation","GLYCGREAT-PWY // HumanCyc","---"
"216944_s_at",-1.616249765,-1.759142073,-2.054137578,"DOWN","U23850","chr3:4558175-4888428 (+) // 99.44 // p26.1","inositol 1,4,5-trisphosphate receptor, type 1","ITPR1","ENSG00000150995 /// OTTHUMG00000154996","3708","147265","NP_001093422 /// NP_001161744 /// NP_002213 /// XP_005265166 /// XP_005265167 /// XP_006713194 /// XP_006713195 /// XP_006713196 /// XP_006713197 /// XP_006713198 /// XP_006713199","NM_001099952 /// NM_001168272 /// NM_002222 /// XM_005265109 /// XM_005265110 /// XM_006713131 /// XM_006713132 /// XM_006713133 /// XM_006713134 /// XM_006713135 /// XM_006713136","0001666 // response to hypoxia // inferred from direct assay /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // non-traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0032469 // endoplasmic reticulum calcium ion homeostasis // inferred from electronic annotation /// 0034220 // ion transmembrane transport // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038096 // Fc-gamma receptor signaling pathway involved in phagocytosis // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048016 // inositol phosphate-mediated signaling // inferred from electronic annotation /// 0048016 // inositol phosphate-mediated signaling // inferred from sequence or structural similarity /// 0048016 // inositol phosphate-mediated signaling // traceable author statement /// 0050796 // regulation of insulin secretion // traceable author statement /// 0050882 // voluntary musculoskeletal movement // inferred from electronic annotation /// 0051209 // release of sequestered calcium ion into cytosol // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0070059 // intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress // inferred from sequence or structural similarity /// 0070588 // calcium ion transmembrane transport // inferred from electronic annotation","0005635 // nuclear envelope // inferred from electronic annotation /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005955 // calcineurin complex // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0031088 // platelet dense granule membrane // inferred from direct assay /// 0031094 // platelet dense tubular network // inferred from direct assay /// 0031095 // platelet dense tubular network membrane // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation","0005216 // ion channel activity // inferred from electronic annotation /// 0005218 // intracellular ligand-gated calcium channel activity // inferred from sequence or structural similarity /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0005220 // inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity // traceable author statement /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015085 // calcium ion transmembrane transporter activity // traceable author statement /// 0035091 // phosphatidylinositol binding // inferred from sequence or structural similarity","Calcium_regulation_in_cardiac_cells // GenMAPP /// G_Protein_Signaling // GenMAPP /// Smooth_muscle_contraction // GenMAPP","IPR000699 // RIH (RyR and IP3R Homology) domain // 8.2E-76 /// IPR000699 // RIH (RyR and IP3R Homology) domain // 2.7E-62 /// IPR000699 // RIH (RyR and IP3R Homology) domain // 8.2E-76 /// IPR000699 // RIH (RyR and IP3R Homology) domain // 2.7E-62 /// IPR000699 // RIH (RyR and IP3R Homology) domain // 8.3E-76 /// IPR000699 // RIH (RyR and IP3R Homology) domain // 2.8E-62 /// IPR000699 // RIH (RyR and IP3R Homology) domain // 8.3E-76 /// IPR000699 // RIH (RyR and IP3R Homology) domain // 2.8E-62 /// IPR005821 // Ion transport domain // 6.0E-16 /// IPR005821 // Ion transport domain // 6.0E-16 /// IPR005821 // Ion transport domain // 6.1E-16 /// IPR005821 // Ion transport domain // 2.0E-17 /// IPR013662 // RyR/IP3R Homology associated domain // 1.4E-35 /// IPR013662 // RyR/IP3R Homology associated domain // 1.4E-35 /// IPR013662 // RyR/IP3R Homology associated domain // 1.4E-35 /// IPR014821 // Inositol 1,4,5-trisphosphate/ryanodine receptor // 1.8E-98 /// IPR014821 // Inositol 1,4,5-trisphosphate/ryanodine receptor // 1.4E-99 /// IPR016093 // MIR motif // 8.2E-75 /// IPR016093 // MIR motif // 1.7E-75 /// IPR016093 // MIR motif // 1.8E-75 /// IPR016093 // MIR motif // 8.3E-75 /// IPR016093 // MIR motif // 1.2E-43"
"217127_at",-1.491197405,-1.291255641,-1.240764783,"DOWN","AL354872","chr1:70877065-70905276 (+) // 100.0 // p31.1","cystathionine gamma-lyase","CTH","ENSG00000116761 /// OTTHUMG00000009352","1491","219500 /// 607657","NP_001177392 /// NP_001893 /// NP_714964 /// XP_005270566","NM_001190463 /// NM_001902 /// NM_153742 /// XM_005270509","0000096 // sulfur amino acid metabolic process // traceable author statement /// 0000098 // sulfur amino acid catabolic process // traceable author statement /// 0006534 // cysteine metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0018272 // protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine // inferred from direct assay /// 0019344 // cysteine biosynthetic process // inferred from direct assay /// 0019344 // cysteine biosynthetic process // inferred from electronic annotation /// 0019346 // transsulfuration // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0044524 // protein sulfhydration // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from physical interaction /// 0070814 // hydrogen sulfide biosynthetic process // inferred from direct assay /// 2001234 // negative regulation of apoptotic signaling pathway // inferred from electronic annotation","0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0003824 // catalytic activity // inferred from electronic annotation /// 0004123 // cystathionine gamma-lyase activity // inferred from direct assay /// 0004123 // cystathionine gamma-lyase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016846 // carbon-sulfur lyase activity // traceable author statement /// 0030170 // pyridoxal phosphate binding // inferred from direct assay /// 0044540 // L-cystine L-cysteine-lyase (deaminating) // inferred from mutant phenotype /// 0047982 // homocysteine desulfhydrase activity // traceable author statement /// 0080146 // L-cysteine desulfhydrase activity // traceable author statement","HOMOCYSDEGR-PWY // HumanCyc /// LCYSDEG-PWY // HumanCyc","IPR000192 // Aminotransferase class V domain // 2.0E-10 /// IPR000192 // Aminotransferase class V domain // 2.6E-8 /// IPR000277 // Cys/Met metabolism, pyridoxal phosphate-dependent enzyme // 1.1E-162 /// IPR000277 // Cys/Met metabolism, pyridoxal phosphate-dependent enzyme // 9.2E-20 /// IPR000277 // Cys/Met metabolism, pyridoxal phosphate-dependent enzyme // 1.0E-123 /// IPR000653 // DegT/DnrJ/EryC1/StrS aminotransferase // 3.1E-10 /// IPR004839 // Aminotransferase, class I/classII // 7.6E-11 /// IPR004839 // Aminotransferase, class I/classII // 6.2E-8"
"217165_x_at",-1.592748731,-1.723644628,-1.800439275,"DOWN","M10943","chr16:56691970-56693076 (+) // 100.0 // q12.2","metallothionein 1F","MT1F","ENSG00000198417 /// OTTHUMG00000176838","4494","156352","NP_005940","NM_005949","0045926 // negative regulation of growth // inferred from sequence or structural similarity /// 0071276 // cellular response to cadmium ion // inferred from expression pattern /// 0071294 // cellular response to zinc ion // inferred from sequence or structural similarity","0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity","0005507 // copper ion binding // non-traceable author statement /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0046870 // cadmium ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR003019 // Metallothionein superfamily, eukaryotic // 4.0E-17 /// IPR003019 // Metallothionein superfamily, eukaryotic // 1.3E-11"
"217232_x_at",-1.535418531,-1.51866603,-1.048838689,"DOWN","AF059180","chr11:5246827-5248277 (-) // 84.35 // p15.4","hemoglobin, beta","HBB","ENSG00000244734 /// OTTHUMG00000066678","3043","140700 /// 141749 /// 141900 /// 603902 /// 603903 /// 604131 /// 611162 /// 613985","NP_000509","NM_000518","0006810 // transport // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0015671 // oxygen transport // non-traceable author statement /// 0015671 // oxygen transport // traceable author statement /// 0015701 // bicarbonate transport // traceable author statement /// 0030185 // nitric oxide transport // non-traceable author statement /// 0042542 // response to hydrogen peroxide // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // non-traceable author statement /// 0050880 // regulation of blood vessel size // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0070293 // renal absorption // inferred from mutant phenotype","0005576 // extracellular region // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005833 // hemoglobin complex // inferred from direct assay /// 0005833 // hemoglobin complex // non-traceable author statement /// 0005833 // hemoglobin complex // traceable author statement /// 0031838 // haptoglobin-hemoglobin complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay","0004601 // peroxidase activity // inferred from direct assay /// 0005344 // oxygen transporter activity // non-traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019825 // oxygen binding // inferred from direct assay /// 0020037 // heme binding // inferred from electronic annotation /// 0030492 // hemoglobin binding // inferred from direct assay /// 0031720 // haptoglobin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000971 // Globin // 3.5E-33"
"217414_x_at",-1.312208284,-1.561181504,-1.772697985,"DOWN","V00489","chr16:222874-223709 (+) // 99.44 // p13.3","hemoglobin, alpha 1 /// hemoglobin, alpha 2","HBA1 /// HBA2","ENSG00000188536 /// OTTHUMG00000059924","3039 /// 3040","140700 /// 141800 /// 141850 /// 604131 /// 613978","NP_000508 /// NP_000549","NM_000517 /// NM_000558","0006810 // transport // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from direct assay /// 0015671 // oxygen transport // traceable author statement /// 0015701 // bicarbonate transport // traceable author statement /// 0042542 // response to hydrogen peroxide // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0044281 // small molecule metabolic process // traceable author statement /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from direct assay","0005576 // extracellular region // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005833 // hemoglobin complex // inferred from direct assay /// 0005833 // hemoglobin complex // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0031838 // haptoglobin-hemoglobin complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071682 // endocytic vesicle lumen // traceable author statement /// 0072562 // blood microparticle // inferred from direct assay","0004601 // peroxidase activity // inferred from direct assay /// 0005344 // oxygen transporter activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019825 // oxygen binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0031720 // haptoglobin binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000971 // Globin // 2.9E-32"
"217428_s_at",2.001340423,1.261650936,2.589976187,"UP","X98568","chr6:116440189-116447296 (-) // 98.09 // q22.1","collagen, type X, alpha 1","COL10A1","ENSG00000123500 /// OTTHUMG00000015426","1300","120110 /// 156500","NP_000484 /// XP_006715395 /// XP_006715396","NM_000493 /// XM_006715332 /// XM_006715333","0001501 // skeletal system development // traceable author statement /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0051216 // cartilage development // inferred from electronic annotation","0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation","0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR001073 // Complement C1q protein // 8.2E-44 /// IPR008160 // Collagen triple helix repeat // 2.1E-9 /// IPR008160 // Collagen triple helix repeat // 1.1E-11 /// IPR008160 // Collagen triple helix repeat // 1.8E-10"
"217546_at",-2.137629325,-1.737060059,-1.043938574,"DOWN","R06655","chr16:56666144-56667893 (+) // 84.27 // q12.2","metallothionein 1M","MT1M","ENSG00000205364 /// OTTHUMG00000176938","4499","156357","NP_789846","NM_176870","0045926 // negative regulation of growth // inferred from sequence or structural similarity /// 0071294 // cellular response to zinc ion // inferred from sequence or structural similarity","0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity","0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR003019 // Metallothionein superfamily, eukaryotic // 2.8E-16"
"217853_at",-1.010897824,-1.31771436,-1.151139674,"DOWN","NM_022748","chr7:47314746-47341826 (-) // 97.26 // p12.3","tensin 3","TNS3","ENSG00000136205 /// OTTHUMG00000074075","64759","606825","NP_073585","NM_022748","0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0048286 // lung alveolus development // inferred from electronic annotation","0005737 // cytoplasm // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation","0005515 // protein binding // inferred from physical interaction /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000980 // SH2 domain // 5.7E-13 /// IPR013625 // Tensin phosphotyrosine-binding domain // 4.3E-47 /// IPR014020 // Tensin phosphatase, C2 domain // 3.0E-32"
"218002_s_at",2.157409597,3.006365002,1.664688655,"UP","NM_004887","chr5:134907475-134914468 (-) // 95.08 // q31.1","chemokine (C-X-C motif) ligand 14","CXCL14","ENSG00000145824 /// OTTHUMG00000129139","9547","604186","NP_004878","NM_004887","0006935 // chemotaxis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0048839 // inner ear development // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement","0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay","0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from electronic annotation","---","IPR001811 // Chemokine interleukin-8-like domain // 1.5E-17 /// IPR001811 // Chemokine interleukin-8-like domain // 2.1E-17"
"218182_s_at",2.862808005,1.542129535,1.170280648,"UP","NM_021101","chr3:190025732-190040217 (-) // 95.8 // q28","claudin 1","CLDN1","ENSG00000163347 /// OTTHUMG00000156214","9076","603718 /// 607626","NP_066924","NM_021101","0007155 // cell adhesion // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016338 // calcium-independent cell-cell adhesion // inferred from sequence or structural similarity /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0045216 // cell-cell junction organization // inferred from mutant phenotype /// 0061436 // establishment of skin barrier // inferred from mutant phenotype","0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from mutant phenotype /// 0005923 // tight junction // inferred from direct assay /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation","0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from sequence or structural similarity","---","IPR004031 // PMP-22/EMP/MP20/Claudin superfamily // 8.0E-57"
"218309_at",2.427054628,2.453358766,2.020635443,"UP","NM_018584","chr1:20808930-20811739 (-) // 91.82 // p36.12","calcium/calmodulin-dependent protein kinase II inhibitor 1","CAMK2N1","ENSG00000162545 /// OTTHUMG00000002837","55450","614986","NP_061054","NM_018584","0006469 // negative regulation of protein kinase activity // inferred from electronic annotation","0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation","0004860 // protein kinase inhibitor activity // inferred from electronic annotation /// 0008427 // calcium-dependent protein kinase inhibitor activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation","---","---"
"218313_s_at",1.746184361,1.78553539,1.715348075,"UP","NM_017423","chr4:174089954-174245117 (+) // 99.34 // q34.1","polypeptide N-acetylgalactosaminyltransferase 7","GALNT7","ENSG00000109586 /// OTTHUMG00000160817","51809","605005","NP_059119 /// XP_005263119","NM_017423 /// XM_005263062","0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement","0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000772 // Ricin B lectin domain // 1.5E-24 /// IPR001173 // Glycosyltransferase 2-like // 4.7E-27"
"218319_at",1.658178878,1.381499284,1.024516279,"UP","NM_020651","chr2:64319994-64339483 (-) // 64.46 // p14","pellino E3 ubiquitin protein ligase 1","PELI1","ENSG00000197329 /// OTTHUMG00000129511","57162","614797","NP_065702 /// XP_005264493 /// XP_005264494","NM_020651 /// XM_005264436 /// XM_005264437","0000209 // protein polyubiquitination // inferred from electronic annotation /// 0001819 // positive regulation of cytokine production // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0008063 // Toll signaling pathway // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from electronic annotation /// 0031398 // positive regulation of protein ubiquitination // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034141 // positive regulation of toll-like receptor 3 signaling pathway // inferred from electronic annotation /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034145 // positive regulation of toll-like receptor 4 signaling pathway // inferred from electronic annotation /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0043331 // response to dsRNA // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0050868 // negative regulation of T cell activation // inferred from electronic annotation /// 0050871 // positive regulation of B cell activation // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from electronic annotation","0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement","0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation","---","IPR006800 // Pellino family // 5.0E-242"
"218541_s_at",2.621976209,1.610085762,1.135152972,"UP","NM_020130","chr8:40011002-40012332 (+) // 97.85 // p11.21","chromosome 8 open reading frame 4","C8orf4","ENSG00000176907 /// OTTHUMG00000164045","56892","607702","NP_064515","NM_020130","0006915 // apoptotic process // inferred from electronic annotation","---","---","---","---"
"218613_at",1.836521975,1.448260305,1.500270106,"UP","NM_018422","chr8:18384817-18387684 (-) // 98.06 // p22","pleckstrin and Sec7 domain containing 3","PSD3","ENSG00000156011 /// OTTHUMG00000163711","23362","614440","NP_056125 /// NP_996792 /// XP_005273518 /// XP_006716381 /// XP_006716382 /// XP_006716383 /// XP_006716384 /// XP_006716385","NM_015310 /// NM_206909 /// XM_005273461 /// XM_006716318 /// XM_006716319 /// XM_006716320 /// XM_006716321 /// XM_006716322","0016192 // vesicle-mediated transport // not recorded /// 0030182 // neuron differentiation // not recorded /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // not recorded /// 0043087 // regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // --- /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation","0005802 // trans-Golgi network // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // not recorded /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation","0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005543 // phospholipid binding // inferred from electronic annotation","Proteasome_Degradation // GenMAPP","IPR000904 // Sec7 domain // 8.0E-54 /// IPR000904 // Sec7 domain // 4.3E-52 /// IPR001849 // Pleckstrin homology domain // 2.8E-16 /// IPR001849 // Pleckstrin homology domain // 2.8E-16"
"218691_s_at",1.750393194,1.357991226,1.930997544,"UP","AF153882","chr5:131593386-131609147 (+) // 88.03 // q31.1","PDZ and LIM domain 4","PDLIM4","ENSG00000131435 /// OTTHUMG00000059645","8572","166710 /// 603422","NP_001124499 /// NP_003678 /// XP_006714786","NM_001131027 /// NM_003687 /// XM_006714723","---","---","0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR001478 // PDZ domain // 1.8E-19 /// IPR001781 // Zinc finger, LIM-type // 6.3E-19"
"218802_at",1.208588871,1.283082187,1.157555938,"UP","NM_017918","chr4:110581349-110608868 (+) // 97.85 // q25","coiled-coil domain containing 109B","CCDC109B","ENSG00000005059 /// OTTHUMG00000161103","55013","---","NP_060388 /// XP_006714309","NM_017918 /// XM_006714246","0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0006851 // mitochondrial calcium ion transport // inferred from sequence or structural similarity /// 0051560 // mitochondrial calcium ion homeostasis // inferred from sequence or structural similarity","0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031224 // intrinsic component of membrane // inferred from sequence or structural similarity /// 0031305 // integral component of mitochondrial inner membrane // inferred from direct assay /// 0034704 // calcium channel complex // inferred from sequence or structural similarity /// 1990246 // uniplex complex // inferred from direct assay","0005216 // ion channel activity // inferred from sequence or structural similarity /// 0019855 // calcium channel inhibitor activity // inferred from sequence or structural similarity","---","IPR006769 // Coiled-coil domain containing protein 109, C-terminal // 6.9E-66"
"218856_at",1.534938991,1.152101998,1.493111157,"UP","NM_016629","chr6:47199268-47200053 (-) // 93.86 // p12.3","tumor necrosis factor receptor superfamily, member 21","TNFRSF21","ENSG00000146072 /// OTTHUMG00000014796","27242","605732","NP_055267","NM_014452","0001783 // B cell apoptotic process // inferred from sequence or structural similarity /// 0002250 // adaptive immune response // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from mutant phenotype /// 0006959 // humoral immune response // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0030889 // negative regulation of B cell proliferation // inferred from sequence or structural similarity /// 0031642 // negative regulation of myelination // inferred from mutant phenotype /// 0042130 // negative regulation of T cell proliferation // inferred from sequence or structural similarity /// 0042552 // myelination // inferred from sequence or structural similarity /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048713 // regulation of oligodendrocyte differentiation // inferred from sequence or structural similarity /// 0050852 // T cell receptor signaling pathway // inferred from sequence or structural similarity /// 0051402 // neuron apoptotic process // inferred from sequence or structural similarity /// 0071356 // cellular response to tumor necrosis factor // inferred from direct assay /// 0097252 // oligodendrocyte apoptotic process // inferred from sequence or structural similarity /// 2000663 // negative regulation of interleukin-5 secretion // inferred from sequence or structural similarity /// 2000666 // negative regulation of interleukin-13 secretion // inferred from sequence or structural similarity /// 2001180 // negative regulation of interleukin-10 secretion // inferred from sequence or structural similarity","0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0031226 // intrinsic component of plasma membrane // inferred from sequence or structural similarity","0005515 // protein binding // inferred from physical interaction","Apoptosis // GenMAPP","IPR000488 // Death domain // 4.4E-18"
"218858_at",-2.115640829,-1.777501575,-1.875682759,"DOWN","NM_022783","chr8:120885964-121062756 (+) // 95.75 // q24.12","DEP domain containing MTOR-interacting protein","DEPTOR","ENSG00000155792 /// OTTHUMG00000165052","64798","612974","NP_001269941 /// NP_073620","NM_001283012 /// NM_022783","0006469 // negative regulation of protein kinase activity // inferred from mutant phenotype /// 0032007 // negative regulation of TOR signaling // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0045792 // negative regulation of cell size // inferred from mutant phenotype /// 2001236 // regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype","0005622 // intracellular // inferred from direct assay","0005515 // protein binding // inferred from physical interaction","---","IPR000591 // DEP domain // 3.3E-28 /// IPR000591 // DEP domain // 5.6E-23"
"218960_at",1.421064993,1.905958905,3.206319194,"UP","NM_016425","chr11:117947810-117989165 (+) // 98.8 // q23.3","transmembrane protease, serine 4","TMPRSS4","ENSG00000137648 /// OTTHUMG00000164122","56649","606565","NP_001077416 /// NP_001167022 /// NP_001167023 /// NP_001277023 /// NP_001277025 /// NP_063947 /// XP_005271670 /// XP_005271671 /// XP_005271672 /// XP_006718946 /// XP_006718947 /// XP_006718948","NM_001083947 /// NM_001173551 /// NM_001173552 /// NM_001290094 /// NM_001290096 /// NM_019894 /// NM_183247 /// NR_110734 /// XM_005271613 /// XM_005271614 /// XM_005271615 /// XM_006718883 /// XM_006718884 /// XM_006718885","0006508 // proteolysis // non-traceable author statement /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation","0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement","0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation","---","IPR001254 // Peptidase S1 // 7.9E-69 /// IPR001254 // Peptidase S1 // 3.1E-34 /// IPR001254 // Peptidase S1 // 8.0E-69 /// IPR001254 // Peptidase S1 // 7.8E-69 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 8.8E-9 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 6.3E-9 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 8.8E-9 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 8.7E-9 /// IPR015420 // Peptidase S1A, nudel // 4.0E-10 /// IPR015420 // Peptidase S1A, nudel // 2.6E-10 /// IPR015420 // Peptidase S1A, nudel // 4.0E-10 /// IPR015420 // Peptidase S1A, nudel // 3.9E-10"
"219049_at",-2.485324178,-1.98855081,-1.559248592,"DOWN","NM_018371","chr8:19261809-19316091 (-) // 94.99 // p21.3","chondroitin sulfate N-acetylgalactosaminyltransferase 1","CSGALNACT1","ENSG00000147408 /// OTTHUMG00000130827","55790","---","NP_001123990 /// NP_060841 /// XP_006716421 /// XP_006716422 /// XP_006716423 /// XP_006716424 /// XP_006716425 /// XP_006716426 /// XP_006716427 /// XP_006716428 /// XP_006716429","NM_001130518 /// NM_018371 /// NR_024040 /// XM_006716358 /// XM_006716359 /// XM_006716360 /// XM_006716361 /// XM_006716362 /// XM_006716363 /// XM_006716364 /// XM_006716365 /// XM_006716366","0001958 // endochondral ossification // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007399 // nervous system development // non-traceable author statement /// 0008037 // cell recognition // non-traceable author statement /// 0008283 // cell proliferation // non-traceable author statement /// 0009653 // anatomical structure morphogenesis // non-traceable author statement /// 0015014 // heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process // non-traceable author statement /// 0019276 // UDP-N-acetylgalactosamine metabolic process // inferred from direct assay /// 0030166 // proteoglycan biosynthetic process // inferred from sequence or structural similarity /// 0030198 // extracellular matrix organization // non-traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // inferred from direct assay /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030210 // heparin biosynthetic process // non-traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046398 // UDP-glucuronate metabolic process // inferred from direct assay /// 0050650 // chondroitin sulfate proteoglycan biosynthetic process // inferred from sequence or structural similarity /// 0050651 // dermatan sulfate proteoglycan biosynthetic process // inferred from sequence or structural similarity /// 0050653 // chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process // inferred from direct assay /// 0051216 // cartilage development // inferred from electronic annotation","0000139 // Golgi membrane // traceable author statement /// 0005622 // intracellular // inferred by curator /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // non-traceable author statement /// 0032580 // Golgi cisterna membrane // inferred from electronic annotation","0008376 // acetylgalactosaminyltransferase activity // inferred from direct assay /// 0008376 // acetylgalactosaminyltransferase activity // inferred from sequence or structural similarity /// 0008955 // peptidoglycan glycosyltransferase activity // inferred from direct assay /// 0015020 // glucuronosyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // non-traceable author statement /// 0047237 // glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity // inferred from direct assay /// 0047238 // glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity // inferred from direct assay","PWY-6566 // MetaCyc /// PWY-6567 // MetaCyc","IPR008428 // Chondroitin N-acetylgalactosaminyltransferase // 1.7E-62 /// IPR008428 // Chondroitin N-acetylgalactosaminyltransferase // 6.1E-9"
"219059_s_at",-3.05572402,-1.125736858,-1.461596511,"DOWN","AL574194","chr11:10579351-10590164 (-) // 96.83 // p15.4","lymphatic vessel endothelial hyaluronan receptor 1","LYVE1","ENSG00000133800 /// OTTHUMG00000165713","10894","605702","NP_006682","NM_006691","0005975 // carbohydrate metabolic process // traceable author statement /// 0006027 // glycosaminoglycan catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0009611 // response to wounding // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030212 // hyaluronan metabolic process // traceable author statement /// 0030214 // hyaluronan catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement","0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071944 // cell periphery // inferred from electronic annotation","0004872 // receptor activity // traceable author statement /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0005540 // hyaluronic acid binding // inferred from electronic annotation","---","IPR000538 // Link // 3.8E-20"
"219077_s_at",-1.395832906,-1.077805987,-1.513177695,"DOWN","NM_016373","chr16:78133550-79246563 (+) // 98.94 // q23.1","WW domain containing oxidoreductase","WWOX","ENSG00000186153 /// OTTHUMG00000176851","51741","605131","NP_001278926 /// NP_057457 /// NP_570607 /// NP_570859 /// XP_006721258","NM_001291997 /// NM_016373 /// NM_018560 /// NM_130788 /// NM_130790 /// NM_130791 /// NM_130792 /// NM_130844 /// NR_120435 /// NR_120436 /// XM_006721195 /// XR_243411","0001649 // osteoblast differentiation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030178 // negative regulation of Wnt signaling pathway // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0048705 // skeletal system morphogenesis // inferred from sequence or structural similarity /// 0055114 // oxidation-reduction process // traceable author statement /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from direct assay /// 0072332 // intrinsic apoptotic signaling pathway by p53 class mediator // inferred from electronic annotation /// 0097191 // extrinsic apoptotic signaling pathway // inferred from electronic annotation /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from sequence or structural similarity /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from electronic annotation","0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005902 // microvillus // inferred from direct assay","0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // non-traceable author statement /// 0016491 // oxidoreductase activity // traceable author statement /// 0019899 // enzyme binding // inferred from physical interaction /// 0046983 // protein dimerization activity // traceable author statement /// 0048037 // cofactor binding // traceable author statement /// 0050662 // coenzyme binding // traceable author statement","---","IPR001202 // WW domain // 9.1E-13 /// IPR001202 // WW domain // 5.7E-13 /// IPR001202 // WW domain // 2.1E-13 /// IPR001202 // WW domain // 1.3E-13 /// IPR001202 // WW domain // 2.8E-13 /// IPR001202 // WW domain // 1.8E-13 /// IPR001202 // WW domain // 1.2E-13 /// IPR001202 // WW domain // 7.8E-14 /// IPR002198 // Short-chain dehydrogenase/reductase SDR // 7.5E-22 /// IPR002198 // Short-chain dehydrogenase/reductase SDR // 2.2E-11 /// IPR013968 // Polyketide synthase, KR // 3.2E-11"
"219093_at",-1.885429063,-1.414441415,-1.967575896,"DOWN","NM_017933","chr2:229888710-230020682 (-) // 82.49 // q36.3","phosphotyrosine interaction domain containing 1","PID1","ENSG00000153823 /// OTTHUMG00000133191","55022","612930","NP_001094288 /// NP_060403","NM_001100818 /// NM_017933","0001933 // negative regulation of protein phosphorylation // inferred from direct assay /// 0006112 // energy reserve metabolic process // inferred by curator /// 0010628 // positive regulation of gene expression // inferred from mutant phenotype /// 0010635 // regulation of mitochondrial fusion // inferred by curator /// 0044320 // cellular response to leptin stimulus // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046325 // negative regulation of glucose import // inferred from electronic annotation /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from direct assay /// 0051881 // regulation of mitochondrial membrane potential // inferred from sequence or structural similarity /// 0051881 // regulation of mitochondrial membrane potential // traceable author statement /// 0070346 // positive regulation of fat cell proliferation // inferred from direct assay /// 0070584 // mitochondrion morphogenesis // inferred from mutant phenotype /// 0071345 // cellular response to cytokine stimulus // inferred from sequence or structural similarity /// 0071354 // cellular response to interleukin-6 // inferred from sequence or structural similarity /// 0071356 // cellular response to tumor necrosis factor // inferred from sequence or structural similarity /// 0071356 // cellular response to tumor necrosis factor // non-traceable author statement /// 0071398 // cellular response to fatty acid // inferred from sequence or structural similarity /// 0090005 // negative regulation of establishment of protein localization to plasma membrane // inferred from direct assay /// 0090298 // negative regulation of mitochondrial DNA replication // inferred from mutant phenotype /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from direct assay /// 2000377 // regulation of reactive oxygen species metabolic process // inferred from sequence or structural similarity /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from mutant phenotype /// 2001170 // negative regulation of ATP biosynthetic process // inferred from mutant phenotype /// 2001171 // positive regulation of ATP biosynthetic process // inferred from sequence or structural similarity /// 2001274 // negative regulation of glucose import in response to insulin stimulus // inferred from direct assay","0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay","0005515 // protein binding // inferred from electronic annotation","---","IPR006020 // PTB/PI domain // 1.9E-10 /// IPR006020 // PTB/PI domain // 6.5E-11 /// IPR006020 // PTB/PI domain // 1.4E-10"
"219127_at",-1.798152795,-1.05491037,-1.281323617,"DOWN","NM_024320","chr17:46029335-46035110 (-) // 97.87 // q21.32","proline rich 15-like","PRR15L","ENSG00000167183 /// OTTHUMG00000178297","79170","---","NP_077296 /// XP_005257720 /// XP_005257721 /// XP_005257722 /// XP_005257723","NM_024320 /// XM_005257663 /// XM_005257664 /// XM_005257665 /// XM_005257666","---","---","---","---","---"
"219181_at",-1.550427551,-1.181678405,-1.531509107,"DOWN","NM_006033","chr18:47088426-47119064 (+) // 86.5 // q21.1","lipase, endothelial","LIPG","ENSG00000101670 /// OTTHUMG00000179658","9388","603684","NP_006024 /// XP_005258447","NM_006033 /// XM_005258390","0006629 // lipid metabolic process // traceable author statement /// 0007584 // response to nutrient // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009395 // phospholipid catabolic process // non-traceable author statement /// 0010983 // positive regulation of high-density lipoprotein particle clearance // inferred from mutant phenotype /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0032376 // positive regulation of cholesterol transport // inferred from direct assay /// 0034375 // high-density lipoprotein particle remodeling // inferred from mutant phenotype /// 0042632 // cholesterol homeostasis // inferred from mutant phenotype /// 0043691 // reverse cholesterol transport // inferred from mutant phenotype /// 0050746 // regulation of lipoprotein metabolic process // inferred from electronic annotation /// 0055091 // phospholipid homeostasis // inferred from mutant phenotype","0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay","0003824 // catalytic activity // inferred from electronic annotation /// 0004465 // lipoprotein lipase activity // inferred from electronic annotation /// 0004620 // phospholipase activity // inferred from direct assay /// 0004806 // triglyceride lipase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0008970 // phosphatidylcholine 1-acylhydrolase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation","LIPAS-PWY // HumanCyc","IPR001024 // PLAT/LH2 domain // 7.9E-35 /// IPR013818 // Lipase, N-terminal // 1.3E-104"
"219195_at",-2.82041239,-2.028097287,-2.508600172,"DOWN","NM_013261","chr4:23793644-23891700 (-) // 96.91 // p15.2","peroxisome proliferator-activated receptor gamma, coactivator 1 alpha","PPARGC1A","ENSG00000109819 /// OTTHUMG00000097747","10891","604517","NP_037393 /// XP_005248187 /// XP_005248188 /// XP_005248189 /// XP_005248191","NM_013261 /// XM_005248130 /// XM_005248131 /// XM_005248132 /// XM_005248134","0001659 // temperature homeostasis // traceable author statement /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001678 // cellular glucose homeostasis // non-traceable author statement /// 0006012 // galactose metabolic process // inferred from electronic annotation /// 0006094 // gluconeogenesis // non-traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006397 // mRNA processing // traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0007005 // mitochondrion organization // non-traceable author statement /// 0007586 // digestion // traceable author statement /// 0008209 // androgen metabolic process // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0009409 // response to cold // inferred from electronic annotation /// 0010822 // positive regulation of mitochondrion organization // inferred from sequence or structural similarity /// 0010941 // regulation of cell death // inferred from direct assay /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014823 // response to activity // inferred from electronic annotation /// 0014850 // response to muscle activity // inferred from sequence or structural similarity /// 0019395 // fatty acid oxidation // non-traceable author statement /// 0022904 // respiratory electron transport chain // inferred from sequence or structural similarity /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0031325 // positive regulation of cellular metabolic process // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032922 // circadian regulation of gene expression // inferred from sequence or structural similarity /// 0034599 // cellular response to oxidative stress // inferred from sequence or structural similarity /// 0035066 // positive regulation of histone acetylation // traceable author statement /// 0036273 // response to statin // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042594 // response to starvation // non-traceable author statement /// 0042752 // regulation of circadian rhythm // inferred from sequence or structural similarity /// 0043201 // response to leucine // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from sequence or structural similarity /// 0045333 // cellular respiration // traceable author statement /// 0045722 // positive regulation of gluconeogenesis // traceable author statement /// 0045820 // negative regulation of glycolytic process // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046321 // positive regulation of fatty acid oxidation // traceable author statement /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050821 // protein stabilization // traceable author statement /// 0050873 // brown fat cell differentiation // traceable author statement /// 0051091 // positive regulation of sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0051552 // flavone metabolic process // inferred from electronic annotation /// 0070997 // neuron death // inferred from direct assay /// 0071250 // cellular response to nitrite // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071398 // cellular response to fatty acid // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0071871 // response to epinephrine // inferred from electronic annotation /// 0071873 // response to norepinephrine // inferred from electronic annotation /// 0097067 // cellular response to thyroid hormone stimulus // inferred from electronic annotation /// 1901857 // positive regulation of cellular respiration // inferred from electronic annotation /// 1901860 // positive regulation of mitochondrial DNA metabolic process // inferred from electronic annotation /// 1901863 // positive regulation of muscle tissue development // inferred from electronic annotation /// 2000272 // negative regulation of receptor activity // inferred from electronic annotation /// 2000310 // regulation of N-methyl-D-aspartate selective glutamate receptor activity // inferred from electronic annotation /// 2000507 // positive regulation of energy homeostasis // inferred from sequence or structural similarity /// 2001171 // positive regulation of ATP biosynthetic process // inferred from sequence or structural similarity","0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005665 // DNA-directed RNA polymerase II, core complex // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016605 // PML body // inferred from electronic annotation","0000166 // nucleotide binding // inferred from electronic annotation /// 0001104 // RNA polymerase II transcription cofactor activity // traceable author statement /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // traceable author statement /// 0016922 // ligand-dependent nuclear receptor binding // inferred from physical interaction /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from direct assay /// 0031490 // chromatin DNA binding // inferred from sequence or structural similarity /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0050681 // androgen receptor binding // non-traceable author statement","---","IPR000504 // RNA recognition motif domain // 7.0E-12"
"219230_at",1.98979104,1.113685211,1.385401647,"UP","NM_018286","chr17:53796989-53800142 (-) // 99.94 // q22","transmembrane protein 100","TMEM100","ENSG00000166292 /// OTTHUMG00000177858","55273","---","NP_001093110 /// NP_060756","NM_001099640 /// NM_018286","0001525 // angiogenesis // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from direct assay /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0045603 // positive regulation of endothelial cell differentiation // inferred from sequence or structural similarity /// 0060842 // arterial endothelial cell differentiation // inferred from electronic annotation /// 0071773 // cellular response to BMP stimulus // inferred from direct assay /// 2001214 // positive regulation of vasculogenesis // inferred from sequence or structural similarity","0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043204 // perikaryon // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay","---","---","---"
"219277_s_at",-2.348964618,-1.552882655,-1.546621576,"DOWN","NM_018245","chr10:50942710-50970369 (-) // 99.29 // q11.23","oxoglutarate dehydrogenase-like","OGDHL","ENSG00000197444 /// OTTHUMG00000018200","55753","---","NP_001137468 /// NP_001137469 /// NP_060715","NM_001143996 /// NM_001143997 /// NM_018245","0006096 // glycolytic process // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation","0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation","0004591 // oxoglutarate dehydrogenase (succinyl-transferring) activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016624 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor // inferred from electronic annotation /// 0030976 // thiamine pyrophosphate binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","GLUCAT-PWY // HumanCyc /// PWY-5084 // HumanCyc /// PWY-5690 // HumanCyc /// TCA // HumanCyc","IPR001017 // Dehydrogenase, E1 component // 2.4E-85 /// IPR001017 // Dehydrogenase, E1 component // 2.1E-85 /// IPR001017 // Dehydrogenase, E1 component // 1.5E-85 /// IPR005475 // Transketolase-like, pyrimidine-binding domain // 1.7E-72 /// IPR005475 // Transketolase-like, pyrimidine-binding domain // 1.5E-72 /// IPR005475 // Transketolase-like, pyrimidine-binding domain // 1.1E-72"
"219463_at",1.557724894,1.463477321,1.887749183,"UP","NM_012261","chr20:9495297-9511171 (+) // 100.0 // p12.2","lysosomal-associated membrane protein family, member 5","LAMP5","ENSG00000125869 /// OTTHUMG00000031851","24141","614641","NP_001186826 /// NP_036393","NM_001199897 /// NM_012261","---","0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from sequence or structural similarity /// 0032584 // growth cone membrane // inferred from sequence or structural similarity /// 0032590 // dendrite membrane // inferred from sequence or structural similarity /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from sequence or structural similarity","---","---","IPR002000 // Lysosome-associated membrane glycoprotein // 1.1E-25"
"219619_at",-2.51362341,-1.32018662,-1.790258896,"DOWN","NM_017594","chr9:93372114-93375139 (-) // 98.59 // q22.2","DIRAS family, GTP-binding RAS-like 2","DIRAS2","ENSG00000165023 /// OTTHUMG00000020196","54769","607863","NP_060064","NM_017594","0006184 // GTP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from direct assay","0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation","0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0051019 // mitogen-activated protein kinase binding // inferred from physical interaction","---","IPR001806 // Small GTPase superfamily // 7.1E-53 /// IPR013684 // Mitochondrial Rho-like // 1.2E-26"
"219628_at",1.663460858,1.500272082,1.546000274,"UP","NM_022470","chr3:178741526-178789583 (-) // 85.0 // q26.32","zinc finger, matrin-type 3","ZMAT3","ENSG00000172667 /// OTTHUMG00000157290","64393","606452","NP_071915 /// NP_689426 /// XP_005247763 /// XP_006713788 /// XP_006713789","NM_022470 /// NM_152240 /// XM_005247706 /// XM_006713725 /// XM_006713726","0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation","0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation","0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR022755 // Zinc finger, double-stranded RNA binding // 3.0E-11 /// IPR022755 // Zinc finger, double-stranded RNA binding // 5.7E-11 /// IPR022755 // Zinc finger, double-stranded RNA binding // 1.9E-9 /// IPR022755 // Zinc finger, double-stranded RNA binding // 5.6E-11 /// IPR022755 // Zinc finger, double-stranded RNA binding // 1.9E-9"
"219630_at",3.002634319,2.575105551,1.331294591,"UP","NM_005764","chr1:47649265-47655727 (-) // 91.15 // p33","PDZK1 interacting protein 1","PDZK1IP1","ENSG00000162366 /// OTTHUMG00000007852","10158","607178","NP_005755","NM_005764","---","0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","---","---","---"
"219643_at",-3.565716991,-2.87807052,-2.070564697,"DOWN","NM_018557","chr2:140988995-142889270 (-) // 98.79 // q22.1","low density lipoprotein receptor-related protein 1B","LRP1B","ENSG00000168702 /// OTTHUMG00000131799","53353","608766","NP_061027","NM_018557","0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0015031 // protein transport // traceable author statement","0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay","0005041 // low-density lipoprotein receptor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation","---","IPR000033 // LDLR class B repeat // 5.5E-10 /// IPR000033 // LDLR class B repeat // 8.5E-8 /// IPR000033 // LDLR class B repeat // 3.8E-9 /// IPR000033 // LDLR class B repeat // 7.0E-9 /// IPR000033 // LDLR class B repeat // 5.3E-10 /// IPR000033 // LDLR class B repeat // 1.7E-14 /// IPR000033 // LDLR class B repeat // 1.1E-10 /// IPR000033 // LDLR class B repeat // 5.2E-12 /// IPR000033 // LDLR class B repeat // 5.3E-13 /// IPR000033 // LDLR class B repeat // 2.1E-10 /// IPR000033 // LDLR class B repeat // 1.3E-12 /// IPR000033 // LDLR class B repeat // 2.0E-8 /// IPR000033 // LDLR class B repeat // 6.4E-8 /// IPR000033 // LDLR class B repeat // 4.3E-10 /// IPR000742 // Epidermal growth factor-like domain // 1.9E-8 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.2E-11 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 2.3E-9 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 2.0E-14 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 2.5E-12 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 6.5E-15 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.5E-14 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.8E-14 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 2.7E-13 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 4.8E-11 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.1E-8 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.1E-10 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 7.2E-11 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 5.3E-14 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.2E-10 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 7.4E-13 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 9.2E-12 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 2.1E-14 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 7.4E-13 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 2.5E-12 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 9.8E-13 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.9E-12 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 2.1E-12 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.6E-11 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 4.7E-15 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 5.9E-16 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 3.0E-12 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 4.2E-15 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 6.9E-13 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 7.0E-16 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.1E-9 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 6.6E-14"
"219735_s_at",-1.97637852,-1.190577044,-2.952612163,"DOWN","NM_014553","chr2:121978533-122042775 (-) // 66.37 // q14.2","transcription factor CP2-like 1","TFCP2L1","ENSG00000115112 /// OTTHUMG00000131443","29842","609785","NP_055368 /// XP_005263708 /// XP_005263709 /// XP_006712522","NM_014553 /// XM_005263651 /// XM_005263652 /// XM_006712459","0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0002070 // epithelial cell maturation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006694 // steroid biosynthetic process // traceable author statement /// 0007028 // cytoplasm organization // inferred from electronic annotation /// 0007431 // salivary gland development // inferred from electronic annotation /// 0007565 // female pregnancy // traceable author statement /// 0008340 // determination of adult lifespan // inferred from electronic annotation /// 0045927 // positive regulation of growth // inferred from electronic annotation","0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation","0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation","---","IPR007604 // CP2 transcription factor // 4.4E-75"
"219743_at",2.333206043,1.480680426,1.571564409,"UP","NM_012259","chr6:126070872-126082417 (+) // 100.0 // q22.31","hes-related family bHLH transcription factor with YRPW motif 2","HEY2","ENSG00000135547 /// OTTHUMG00000015512","23493","604674","NP_036391 /// XP_005266935 /// XP_006715491","NM_012259 /// XM_005266878 /// XM_006715428","0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from sequence or structural similarity /// 0003150 // muscular septum morphogenesis // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003171 // atrioventricular valve development // inferred from electronic annotation /// 0003184 // pulmonary valve morphogenesis // inferred from sequence or structural similarity /// 0003186 // tricuspid valve morphogenesis // inferred from sequence or structural similarity /// 0003195 // tricuspid valve formation // inferred from electronic annotation /// 0003199 // endocardial cushion to mesenchymal transition involved in heart valve formation // inferred from electronic annotation /// 0003208 // cardiac ventricle morphogenesis // inferred from sequence or structural similarity /// 0003214 // cardiac left ventricle morphogenesis // inferred from sequence or structural similarity /// 0003215 // cardiac right ventricle morphogenesis // inferred from sequence or structural similarity /// 0003222 // ventricular trabecula myocardium morphogenesis // inferred from electronic annotation /// 0003300 // cardiac muscle hypertrophy // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007219 // Notch signaling pathway // inferred from sequence or structural similarity /// 0007219 // Notch signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0009948 // anterior/posterior axis specification // inferred from electronic annotation /// 0010460 // positive regulation of heart rate // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010621 // negative regulation of transcription by transcription factor localization // inferred from sequence or structural similarity /// 0010629 // negative regulation of gene expression // inferred from sequence or structural similarity /// 0010667 // negative regulation of cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0014031 // mesenchymal cell development // inferred from sequence or structural similarity /// 0014898 // cardiac muscle hypertrophy in response to stress // inferred from electronic annotation /// 0035910 // ascending aorta morphogenesis // inferred from sequence or structural similarity /// 0035912 // dorsal aorta morphogenesis // inferred from sequence or structural similarity /// 0036304 // umbilical cord morphogenesis // inferred from sequence or structural similarity /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045607 // regulation of auditory receptor cell differentiation // inferred from electronic annotation /// 0045746 // negative regulation of Notch signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0051145 // smooth muscle cell differentiation // non-traceable author statement /// 0055015 // ventricular cardiac muscle cell development // inferred from sequence or structural similarity /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060317 // cardiac epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0060347 // heart trabecula formation // inferred from electronic annotation /// 0060411 // cardiac septum morphogenesis // inferred from sequence or structural similarity /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0060413 // atrial septum morphogenesis // inferred from sequence or structural similarity /// 0060633 // negative regulation of transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0060716 // labyrinthine layer blood vessel development // inferred from sequence or structural similarity /// 0060840 // artery development // inferred from electronic annotation /// 0060842 // arterial endothelial cell differentiation // inferred from sequence or structural similarity /// 0060948 // cardiac vascular smooth muscle cell development // inferred from electronic annotation /// 0060977 // coronary vasculature morphogenesis // inferred from electronic annotation /// 0061156 // pulmonary artery morphogenesis // inferred from sequence or structural similarity /// 0061314 // Notch signaling involved in heart development // inferred by curator /// 0065004 // protein-DNA complex assembly // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation /// 0097084 // vascular smooth muscle cell development // inferred from expression pattern /// 2000678 // negative regulation of transcription regulatory region DNA binding // inferred from direct assay /// 2000723 // negative regulation of cardiac vascular smooth muscle cell differentiation // inferred from sequence or structural similarity /// 2000820 // negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation // inferred from sequence or structural similarity /// 2001212 // regulation of vasculogenesis // inferred from sequence or structural similarity","0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0016580 // Sin3 complex // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay","0000983 // RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0000988 // protein binding transcription factor activity // inferred from direct assay /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // non-traceable author statement /// 0035939 // microsatellite binding // inferred from direct assay /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from electronic annotation","---","IPR003650 // Orange // 1.6E-17 /// IPR003650 // Orange // 2.0E-17 /// IPR011598 // Myc-type, basic helix-loop-helix (bHLH) domain // 3.5E-21 /// IPR011598 // Myc-type, basic helix-loop-helix (bHLH) domain // 4.4E-21"
"219773_at",2.094352287,1.33465262,1.400964329,"UP","NM_016931","chr11:89059514-89224500 (-) // 98.61 // q14.3","NADPH oxidase 4","NOX4","ENSG00000086991 /// OTTHUMG00000167298","50507","605261","NP_001137308 /// NP_001137309 /// NP_001278855 /// NP_001278856 /// NP_001278858 /// NP_058627 /// XP_006718910 /// XP_006718911 /// XP_006718912 /// XP_006718913 /// XP_006718914 /// XP_006718915 /// XP_006718916","NM_001143836 /// NM_001143837 /// NM_001291926 /// NM_001291927 /// NM_001291929 /// NM_016931 /// NR_026571 /// NR_120406 /// XM_006718847 /// XM_006718848 /// XM_006718849 /// XM_006718850 /// XM_006718851 /// XM_006718852 /// XM_006718853 /// XR_428978 /// XR_428979","0000902 // cell morphogenesis // inferred from sequence or structural similarity /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0006801 // superoxide metabolic process // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0007569 // cell aging // inferred from sequence or structural similarity /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0014911 // positive regulation of smooth muscle cell migration // inferred from electronic annotation /// 0035051 // cardiocyte differentiation // inferred from electronic annotation /// 0042554 // superoxide anion generation // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0045453 // bone resorption // inferred from electronic annotation /// 0050667 // homocysteine metabolic process // inferred from direct assay /// 0051496 // positive regulation of stress fiber assembly // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from direct assay /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0071320 // cellular response to cAMP // inferred from electronic annotation /// 0071333 // cellular response to glucose stimulus // inferred from electronic annotation /// 0071480 // cellular response to gamma radiation // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from direct assay /// 2000379 // positive regulation of reactive oxygen species metabolic process // inferred from electronic annotation /// 2000573 // positive regulation of DNA biosynthetic process // inferred from electronic annotation","0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043020 // NADPH oxidase complex // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation /// 0071944 // cell periphery // inferred from electronic annotation","0000166 // nucleotide binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016174 // NAD(P)H oxidase activity // traceable author statement /// 0016175 // superoxide-generating NADPH oxidase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0019826 // oxygen sensor activity // traceable author statement /// 0020037 // heme binding // traceable author statement /// 0050660 // flavin adenine dinucleotide binding // traceable author statement /// 0050664 // oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor // inferred from electronic annotation /// 0072341 // modified amino acid binding // inferred from direct assay","---","IPR013112 // FAD-binding 8 // 4.6E-18 /// IPR013112 // FAD-binding 8 // 1.7E-15 /// IPR013112 // FAD-binding 8 // 4.9E-18 /// IPR013112 // FAD-binding 8 // 1.6E-15 /// IPR013121 // Ferric reductase, NAD binding // 3.7E-15 /// IPR013121 // Ferric reductase, NAD binding // 4.2E-11 /// IPR013121 // Ferric reductase, NAD binding // 4.0E-11 /// IPR013121 // Ferric reductase, NAD binding // 1.4E-11 /// IPR013121 // Ferric reductase, NAD binding // 3.9E-15 /// IPR013121 // Ferric reductase, NAD binding // 4.4E-11 /// IPR013121 // Ferric reductase, NAD binding // 3.8E-11 /// IPR013130 // Ferric reductase transmembrane component-like domain // 9.5E-22 /// IPR013130 // Ferric reductase transmembrane component-like domain // 9.0E-22 /// IPR013130 // Ferric reductase transmembrane component-like domain // 2.3E-22 /// IPR013130 // Ferric reductase transmembrane component-like domain // 1.0E-21 /// IPR013130 // Ferric reductase transmembrane component-like domain // 8.2E-22"
"219778_at",-1.782251731,-2.177788759,-1.506713589,"DOWN","NM_012082","chr8:106331146-106816765 (+) // 98.67 // q23.1","zinc finger protein, FOG family member 2","ZFPM2","ENSG00000169946 /// OTTHUMG00000164818","23414","187500 /// 603693 /// 610187","NP_036214 /// XP_005250907","NM_012082 /// XM_005250850","0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0003148 // outflow tract septum morphogenesis // inferred from mutant phenotype /// 0003221 // right ventricular cardiac muscle tissue morphogenesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0030324 // lung development // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0048738 // cardiac muscle tissue development // inferred from electronic annotation /// 0060412 // ventricular septum morphogenesis // inferred from mutant phenotype /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 2000020 // positive regulation of male gonad development // inferred from electronic annotation /// 2000195 // negative regulation of female gonad development // inferred from electronic annotation","0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation","0001071 // nucleic acid binding transcription factor activity // inferred from electronic annotation /// 0001105 // RNA polymerase II transcription coactivator activity // non-traceable author statement /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation","---","---"
"219877_at",-2.474591039,-1.917864338,-2.725145368,"DOWN","NM_024645","chr8:40388112-40755343 (-) // 99.92 // p11.21","zinc finger, matrin-type 4","ZMAT4","ENSG00000165061 /// OTTHUMG00000164049","79698","---","NP_001129203 /// NP_078921 /// XP_005273701 /// XP_006716462 /// XP_006716463 /// XP_006716464","NM_001135731 /// NM_024645 /// XM_005273644 /// XM_006716399 /// XM_006716400 /// XM_006716401","---","0005634 // nucleus // inferred from electronic annotation","0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR022755 // Zinc finger, double-stranded RNA binding // 1.5E-9 /// IPR022755 // Zinc finger, double-stranded RNA binding // 2.2E-9 /// IPR022755 // Zinc finger, double-stranded RNA binding // 5.3E-9 /// IPR022755 // Zinc finger, double-stranded RNA binding // 2.5E-10 /// IPR022755 // Zinc finger, double-stranded RNA binding // 8.1E-9"
"219932_at",2.747144899,2.575755812,1.759275785,"UP","NM_014031","chr5:128301677-128368988 (+) // 99.46 // q23.3","solute carrier family 27 (fatty acid transporter), member 6","SLC27A6","ENSG00000113396 /// OTTHUMG00000128991","28965","604196","NP_001017372 /// NP_054750 /// XP_005272024 /// XP_005272025 /// XP_005272026 /// XP_005272027 /// XP_005272028","NM_001017372 /// NM_014031 /// XM_005271967 /// XM_005271968 /// XM_005271969 /// XM_005271970 /// XM_005271971","0000038 // very long-chain fatty acid metabolic process // traceable author statement /// 0001676 // long-chain fatty acid metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0015909 // long-chain fatty acid transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement","0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation","0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004467 // long-chain fatty acid-CoA ligase activity // traceable author statement /// 0016874 // ligase activity // inferred from electronic annotation /// 0031957 // very long-chain fatty acid-CoA ligase activity // inferred from electronic annotation","---","IPR000873 // AMP-dependent synthetase/ligase // 1.3E-72"
"219949_at",-1.760907769,-1.31761945,-1.511960033,"DOWN","NM_024512","chr3:46556910-46607778 (-) // 67.68 // p21.31","leucine rich repeat containing 2","LRRC2","ENSG00000163827 /// OTTHUMG00000133479","79442","607180","NP_078788 /// XP_006713395","NM_024512 /// NM_024750 /// XM_006713332","---","---","0005515 // protein binding // inferred from electronic annotation","---","IPR001611 // Leucine-rich repeat // 1.3E-5 /// IPR001611 // Leucine-rich repeat // 1.1E-5 /// IPR001611 // Leucine-rich repeat // 3.7E-7"
"220177_s_at",-1.200327305,-1.165035147,-2.095857284,"DOWN","NM_024022","chr21:43791999-43816200 (-) // 86.51 // q22.3","transmembrane protease, serine 3","TMPRSS3","ENSG00000160183 /// OTTHUMG00000086796","64699","605511","NP_001243246 /// NP_076927 /// NP_115780 /// NP_115781","NM_001256317 /// NM_024022 /// NM_032401 /// NM_032404 /// NM_032405 /// NR_046020","0006508 // proteolysis // non-traceable author statement /// 0006883 // cellular sodium ion homeostasis // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation","0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0043025 // neuronal cell body // inferred from electronic annotation","0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // non-traceable author statement /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017080 // sodium channel regulator activity // inferred from direct assay","---","IPR001190 // SRCR domain // 4.3E-13 /// IPR001190 // SRCR domain // 4.3E-13 /// IPR001254 // Peptidase S1 // 9.5E-72 /// IPR001254 // Peptidase S1 // 9.6E-72 /// IPR001254 // Peptidase S1 // 5.0E-71 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 2.4E-9 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 2.4E-9 /// IPR015420 // Peptidase S1A, nudel // 9.4E-12 /// IPR015420 // Peptidase S1A, nudel // 9.5E-12 /// IPR015420 // Peptidase S1A, nudel // 1.3E-11"
"220203_at",-2.154051344,-1.472784261,-2.704715683,"DOWN","NM_024732","chr1:39993502-39995349 (+) // 61.93 // p34.3","bone morphogenetic protein 8a","BMP8A","---","353500","---","NP_861525 /// XP_006710679","NM_181809 /// XM_006710616","0001503 // ossification // inferred from electronic annotation /// 0002024 // diet induced thermogenesis // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from direct assay /// 0051216 // cartilage development // inferred from electronic annotation /// 2000505 // regulation of energy homeostasis // inferred from direct assay","0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation","0005125 // cytokine activity // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation","---","---"
"220723_s_at",-2.711558995,-1.60156595,-3.227790759,"DOWN","NM_025087","chr4:48988264-49064093 (+) // 99.16 // p11","cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)","CWH43","ENSG00000109182 /// OTTHUMG00000128627","80157","---","NP_001273720 /// NP_079363 /// XP_005248183 /// XP_006714093","NM_001286791 /// NM_025087 /// XM_005248126 /// XM_006714030","0006506 // GPI anchor biosynthetic process // inferred from electronic annotation","0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","---","---","---"
"220724_at",-2.759828106,-1.596244127,-1.969700193,"DOWN","NM_025087","chr4:48988264-49064093 (+) // 99.16 // p11","cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)","CWH43","ENSG00000109182 /// OTTHUMG00000128627","80157","---","NP_001273720 /// NP_079363 /// XP_005248183 /// XP_006714093","NM_001286791 /// NM_025087 /// XM_005248126 /// XM_006714030","0006506 // GPI anchor biosynthetic process // inferred from electronic annotation","0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","---","---","---"
"220751_s_at",-1.572091913,-1.348494324,-1.137664345,"DOWN","NM_016348","chr5:154198053-154201086 (-) // 84.27 // q33.2","fatty acid hydroxylase domain containing 2","FAXDC2","ENSG00000170271 /// OTTHUMG00000164141","10826","---","NP_115761 /// XP_005268413 /// XP_005268415 /// XP_006714816","NM_016348 /// NM_032385 /// XM_005268356 /// XM_005268358 /// XM_006714753","0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation","0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation","---","IPR006694 // Fatty acid hydroxylase // 1.9E-18"
"220979_s_at",2.028353598,1.862285463,3.056532804,"UP","NM_030965","chr1:77333185-77529735 (+) // 86.23 // p31.1","ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5","ST6GALNAC5","ENSG00000117069 /// OTTHUMG00000009687","81849","610134","NP_112227 /// XP_005271295","NM_030965 /// XM_005271238","0006486 // protein glycosylation // inferred from electronic annotation /// 0006688 // glycosphingolipid biosynthetic process // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0009312 // oligosaccharide biosynthetic process // inferred from sequence or structural similarity /// 0097503 // sialylation // inferred from electronic annotation /// 0097503 // sialylation // inferred from sequence or structural similarity","0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation","0001665 // alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity // inferred from sequence or structural similarity /// 0008373 // sialyltransferase activity // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation","---","IPR001675 // Glycosyl transferase, family 29 // 1.6E-43 /// IPR001675 // Glycosyl transferase, family 29 // 8.3E-31"
"220987_s_at",-1.798398733,-1.012675885,-1.098751752,"DOWN","NM_030952","chr1:205271192-205290883 (-) // 89.43 // q32.1","A kinase (PRKA) interacting protein 1 /// NUAK family, SNF1-like kinase, 2","AKIP1 /// NUAK2","ENSG00000163545 /// OTTHUMG00000037196","56672 /// 81788","608131 /// 609191","NP_001193575 /// NP_001193576 /// NP_001193577 /// NP_065693 /// NP_112214 /// XP_005245572 /// XP_006718327","NM_001206645 /// NM_001206646 /// NM_001206647 /// NM_001206648 /// NM_020642 /// NM_030952 /// NM_182901 /// NR_045417 /// NR_045418 /// XM_005245515 /// XM_006718264","0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from direct assay /// 0034446 // substrate adhesion-dependent cell spreading // inferred from electronic annotation /// 0042149 // cellular response to glucose starvation // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from direct assay","0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from direct assay","0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0016773 // phosphotransferase activity, alcohol group as acceptor // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000719 // Protein kinase domain // 5.0E-80 /// IPR001245 // Serine-threonine/tyrosine-protein kinase catalytic domain // 2.6E-47 /// IPR010440 // Lipopolysaccharide kinase // 1.2E-9"
"221030_s_at",-1.632534854,-1.056939475,-1.980861293,"DOWN","NM_031305","chr4:86851425-86923821 (+) // 92.31 // q21.23","Rho GTPase activating protein 24","ARHGAP24","ENSG00000138639 /// OTTHUMG00000130427","83478","610586","NP_001020787 /// NP_001036134 /// NP_001274734 /// NP_112595 /// XP_005263320","NM_001025616 /// NM_001042669 /// NM_001287805 /// NM_031305 /// XM_005263263","0001525 // angiogenesis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032863 // activation of Rac GTPase activity // inferred from electronic annotation /// 0035021 // negative regulation of Rac protein signal transduction // inferred from electronic annotation /// 0035313 // wound healing, spreading of epidermal cells // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 1900028 // negative regulation of ruffle assembly // inferred from electronic annotation","0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation","0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030675 // Rac GTPase activator activity // inferred from electronic annotation","---","IPR000198 // Rho GTPase-activating protein domain // 3.4E-53 /// IPR000198 // Rho GTPase-activating protein domain // 1.4E-53 /// IPR001849 // Pleckstrin homology domain // 7.2E-22"
"221073_s_at",1.47363045,1.596967873,1.607882623,"UP","NM_006092","chr7:30464149-30518265 (-) // 99.27 // p14.3","nucleotide-binding oligomerization domain containing 1","NOD1","ENSG00000106100 /// OTTHUMG00000023923","10392","605980","NP_006083 /// XP_005249625 /// XP_005249629 /// XP_005249630 /// XP_005249631 /// XP_005249632 /// XP_005249633 /// XP_006715696 /// XP_006715697 /// XP_006715698 /// XP_006715699 /// XP_006715700","NM_006092 /// XM_005249568 /// XM_005249572 /// XM_005249573 /// XM_005249574 /// XM_005249575 /// XM_005249576 /// XM_006715633 /// XM_006715634 /// XM_006715635 /// XM_006715636 /// XM_006715637 /// XR_428069","0000187 // activation of MAPK activity // traceable author statement /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0002606 // positive regulation of dendritic cell antigen processing and presentation // inferred from sequence or structural similarity /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0006952 // defense response // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007254 // JNK cascade // traceable author statement /// 0009595 // detection of biotic stimulus // traceable author statement /// 0016045 // detection of bacterium // inferred from direct assay /// 0032755 // positive regulation of interleukin-6 production // inferred from electronic annotation /// 0032760 // positive regulation of tumor necrosis factor production // inferred from electronic annotation /// 0032874 // positive regulation of stress-activated MAPK cascade // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042228 // interleukin-8 biosynthetic process // inferred from direct assay /// 0042742 // defense response to bacterium // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0045087 // innate immune response // traceable author statement /// 0046330 // positive regulation of JNK cascade // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // traceable author statement /// 0051259 // protein oligomerization // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from electronic annotation /// 0070423 // nucleotide-binding oligomerization domain containing signaling pathway // traceable author statement","0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation","0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008656 // cysteine-type endopeptidase activator activity involved in apoptotic process // traceable author statement /// 0042802 // identical protein binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0042834 // peptidoglycan binding // traceable author statement /// 0050700 // CARD domain binding // inferred from direct assay","---","IPR001315 // CARD domain // 2.0E-20 /// IPR001315 // CARD domain // 1.5E-20"
"221266_s_at",2.325737318,3.413373003,4.199587208,"UP","NM_030788","chr8:105352053-105368916 (+) // 98.89 // q22.3","dendrocyte expressed seven transmembrane protein","DCSTAMP","ENSG00000164935 /// OTTHUMG00000164890","81501","605933","NP_001244246 /// NP_110415 /// XP_005251132","NM_001257317 /// NM_030788 /// XM_005251075","0002376 // immune system process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from sequence or structural similarity /// 0030316 // osteoclast differentiation // inferred from sequence or structural similarity /// 0034241 // positive regulation of macrophage fusion // inferred from sequence or structural similarity /// 0036006 // cellular response to macrophage colony-stimulating factor stimulus // inferred from sequence or structural similarity /// 0043011 // myeloid dendritic cell differentiation // inferred from sequence or structural similarity /// 0045657 // positive regulation of monocyte differentiation // inferred from sequence or structural similarity /// 0045780 // positive regulation of bone resorption // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0061025 // membrane fusion // inferred from sequence or structural similarity /// 0071353 // cellular response to interleukin-4 // inferred from direct assay /// 0071356 // cellular response to tumor necrosis factor // inferred from sequence or structural similarity /// 0072675 // osteoclast fusion // inferred from sequence or structural similarity","0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0010008 // endosome membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation","0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // inferred from electronic annotation","---","IPR012858 // Dendritic cell-specific transmembrane protein-like // 4.8E-57"
"221577_x_at",2.392772374,3.484244284,2.130913564,"UP","AF003934","chr19:18496997-18499745 (+) // 93.45 // p13.11","growth differentiation factor 15","GDF15","ENSG00000130513 /// OTTHUMG00000183360","9518","605312","NP_004855","NM_004864","0007165 // signal transduction // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement","0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005125 // cytokine activity // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation","---","IPR001839 // Transforming growth factor-beta, C-terminal // 7.8E-25"
"221731_x_at",2.089691783,1.934325863,1.566655002,"UP","BF218922","chr5:82835738-82878121 (+) // 98.73 // q14.3","versican","VCAN","ENSG00000038427 /// OTTHUMG00000131321","1462","118661 /// 143200","NP_001119808 /// NP_001157569 /// NP_001157570 /// NP_004376","NM_001126336 /// NM_001164097 /// NM_001164098 /// NM_004385","0001649 // osteoblast differentiation // inferred from direct assay /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0008037 // cell recognition // traceable author statement /// 0008347 // glial cell migration // inferred from direct assay /// 0030198 // extracellular matrix organization // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0030204 // chondroitin sulfate metabolic process // traceable author statement /// 0030206 // chondroitin sulfate biosynthetic process // traceable author statement /// 0030207 // chondroitin sulfate catabolic process // traceable author statement /// 0030208 // dermatan sulfate biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement","0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay","0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005539 // glycosaminoglycan binding // traceable author statement /// 0005540 // hyaluronic acid binding // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation","---","IPR000436 // Sushi/SCR/CCP // 8.6E-11 /// IPR000436 // Sushi/SCR/CCP // 5.9E-11 /// IPR000436 // Sushi/SCR/CCP // 3.8E-11 /// IPR000538 // Link // 5.9E-41 /// IPR000538 // Link // 3.9E-36 /// IPR000538 // Link // 4.0E-41 /// IPR000538 // Link // 2.6E-36 /// IPR000538 // Link // 2.5E-41 /// IPR000538 // Link // 1.7E-36 /// IPR000742 // Epidermal growth factor-like domain // 1.9E-9 /// IPR000742 // Epidermal growth factor-like domain // 3.8E-9 /// IPR000742 // Epidermal growth factor-like domain // 1.3E-9 /// IPR000742 // Epidermal growth factor-like domain // 2.7E-9 /// IPR000742 // Epidermal growth factor-like domain // 8.7E-10 /// IPR000742 // Epidermal growth factor-like domain // 1.8E-9 /// IPR001304 // C-type lectin // 2.6E-28 /// IPR001304 // C-type lectin // 1.7E-28 /// IPR001304 // C-type lectin // 1.1E-28 /// IPR013106 // Immunoglobulin V-set domain // 9.7E-17 /// IPR013106 // Immunoglobulin V-set domain // 6.5E-17 /// IPR013106 // Immunoglobulin V-set domain // 4.1E-17"
"221840_at",1.193123218,1.646392049,1.379771146,"UP","AA775177","chr10:129839137-129884173 (+) // 97.16 // q26.2","protein tyrosine phosphatase, receptor type, E","PTPRE","ENSG00000132334 /// OTTHUMG00000019254","5791","600926","NP_006495 /// NP_569119 /// XP_005252748 /// XP_005252749 /// XP_006717995","NM_006504 /// NM_130435 /// XM_005252691 /// XM_005252692 /// XM_006717932","0006470 // protein dephosphorylation // traceable author statement /// 0007185 // transmembrane receptor protein tyrosine phosphatase signaling pathway // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0033003 // regulation of mast cell activation // inferred from electronic annotation /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity","0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay","0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation","---","IPR000242 // Protein-tyrosine phosphatase, receptor/non-receptor type // 3.4E-93 /// IPR000242 // Protein-tyrosine phosphatase, receptor/non-receptor type // 8.2E-86 /// IPR000242 // Protein-tyrosine phosphatase, receptor/non-receptor type // 2.9E-93 /// IPR000242 // Protein-tyrosine phosphatase, receptor/non-receptor type // 6.8E-86 /// IPR000242 // Protein-tyrosine phosphatase, receptor/non-receptor type // 1.9E-93"
"221874_at",-1.703074811,-1.029906215,-2.780183087,"DOWN","AB037745","chr1:109731739-109749401 (+) // 77.9 // p13.3","KIAA1324","KIAA1324","ENSG00000116299 /// OTTHUMG00000011725","57535","611298","NP_001253977 /// NP_001271281 /// NP_001271282 /// NP_065826","NM_001267048 /// NM_001267049 /// NM_001284352 /// NM_001284353 /// NM_020775","0006914 // autophagy // inferred from electronic annotation /// 0009267 // cellular response to starvation // inferred from mutant phenotype /// 0016236 // macroautophagy // inferred from mutant phenotype /// 0044090 // positive regulation of vacuole organization // inferred from mutant phenotype /// 2000786 // positive regulation of autophagic vacuole assembly // inferred from mutant phenotype /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype","0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0044822 // poly(A) RNA binding // inferred from direct assay","---","---"
"221900_at",1.350577369,1.500582686,1.295639915,"UP","AI806793","chr1:36560839-36565116 (-) // 99.07 // p34.3","collagen, type VIII, alpha 2","COL8A2","ENSG00000171812 /// OTTHUMG00000007665","1296","120252 /// 136800 /// 609140","NP_001281276 /// NP_005193 /// XP_005270534 /// XP_005270535 /// XP_005270536","NM_001294347 /// NM_005202 /// XM_005270477 /// XM_005270478 /// XM_005270479","0001525 // angiogenesis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // non-traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0050673 // epithelial cell proliferation // inferred from electronic annotation","0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005604 // basement membrane // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay","0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0030674 // protein binding, bridging // non-traceable author statement","---","IPR001073 // Complement C1q protein // 5.1E-42 /// IPR008160 // Collagen triple helix repeat // 6.4E-12 /// IPR008160 // Collagen triple helix repeat // 2.4E-11 /// IPR008160 // Collagen triple helix repeat // 1.7E-10"
"222108_at",2.332402388,1.737875095,1.241932872,"UP","AC004010","chr12:47470255-47472785 (-) // 95.36 // q13.11","adhesion molecule with Ig-like domain 2","AMIGO2","ENSG00000139211 /// OTTHUMG00000169616","347902","615690","NP_001137140 /// NP_862830 /// XP_005268894","NM_001143668 /// NM_181847 /// XM_005268837","0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from sequence or structural similarity /// 0007157 // heterophilic cell-cell adhesion // inferred from sequence or structural similarity /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043069 // negative regulation of programmed cell death // inferred from sequence or structural similarity","0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0005515 // protein binding // inferred from physical interaction","---","IPR001611 // Leucine-rich repeat // 9.1E-5 /// IPR001611 // Leucine-rich repeat // 5.1E-5 /// IPR001611 // Leucine-rich repeat // 7.0E-5 /// IPR001611 // Leucine-rich repeat // 1.0E-5"
"222171_s_at",-1.875779535,-1.491120573,-1.844426984,"DOWN","AK023792","chr11:125295563-125303283 (+) // 80.84 // q24.2","PBX/knotted 1 homeobox 2","PKNOX2","ENSG00000165495 /// OTTHUMG00000165884","63876","613066","NP_071345 /// XP_005271699 /// XP_005271700 /// XP_006718957 /// XP_006718958","NM_022062 /// XM_005271642 /// XM_005271643 /// XM_006718894 /// XM_006718895","0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation","0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation","0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003785 // actin monomer binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation","---","IPR001356 // Homeobox domain // 1.2E-11 /// IPR008422 // Homeobox KN domain // 2.1E-11"
"222173_s_at",1.24467271,1.380730701,1.731450397,"UP","AK026105","chr9:100961320-101017493 (-) // 95.56 // q22.33","TBC1 domain family, member 2","TBC1D2","ENSG00000095383 /// OTTHUMG00000020343","55357","609871","NP_001254500 /// NP_001254501 /// NP_060891","NM_001267571 /// NM_001267572 /// NM_018421 /// NR_051978","0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from direct assay","0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030054 // cell junction // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay","0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from direct assay /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0045296 // cadherin binding // inferred from physical interaction","---","IPR000195 // Rab-GTPase-TBC domain // 7.0E-57 /// IPR000195 // Rab-GTPase-TBC domain // 2.4E-56 /// IPR000195 // Rab-GTPase-TBC domain // 1.7E-56 /// IPR000195 // Rab-GTPase-TBC domain // 1.9E-50"
"222294_s_at",1.229975583,1.650975595,1.023999674,"UP","AW971415","chr15:55495163-55495422 (-) // 53.96 // q21.3","RAB27A, member RAS oncogene family","RAB27A","ENSG00000069974 /// OTTHUMG00000131959","5873","603868 /// 607624","NP_004571 /// NP_899057 /// NP_899058 /// NP_899059 /// XP_005254633 /// XP_005254634","NM_004580 /// NM_183234 /// NM_183235 /// NM_183236 /// XM_005254576 /// XM_005254577","0006184 // GTP catabolic process // inferred from electronic annotation /// 0006605 // protein targeting // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from mutant phenotype /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0032400 // melanosome localization // inferred from electronic annotation /// 0032402 // melanosome transport // inferred from electronic annotation /// 0043316 // cytotoxic T cell degranulation // inferred from electronic annotation /// 0043320 // natural killer cell degranulation // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045921 // positive regulation of exocytosis // inferred from mutant phenotype /// 0051875 // pigment granule localization // inferred from electronic annotation /// 0051904 // pigment granule transport // inferred from electronic annotation /// 0071985 // multivesicular body sorting pathway // inferred from mutant phenotype","0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0030425 // dendrite // inferred from direct assay /// 0030667 // secretory granule membrane // inferred from electronic annotation /// 0032585 // multivesicular body membrane // inferred from direct assay /// 0042470 // melanosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070382 // exocytic vesicle // inferred from direct assay","0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0005525 // GTP binding // inferred from sequence or structural similarity /// 0019003 // GDP binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031489 // myosin V binding // inferred from electronic annotation","---","IPR000795 // Elongation factor, GTP-binding domain // 2.4E-9 /// IPR001806 // Small GTPase superfamily // 8.3E-60 /// IPR006689 // Small GTPase superfamily, ARF/SAR type // 7.1E-15 /// IPR013684 // Mitochondrial Rho-like // 9.8E-20"
"222484_s_at",2.064897262,2.528035933,1.568278007,"UP","AF144103","chr5:134906374-134914475 (-) // 95.01 // q31.1","chemokine (C-X-C motif) ligand 14","CXCL14","ENSG00000145824 /// OTTHUMG00000129139","9547","604186","NP_004878","NM_004887","0006935 // chemotaxis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0048839 // inner ear development // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement","0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay","0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // inferred from electronic annotation","---","IPR001811 // Chemokine interleukin-8-like domain // 1.5E-17 /// IPR001811 // Chemokine interleukin-8-like domain // 2.1E-17"
"222549_at",3.820022539,3.711721184,2.41548962,"UP","AF101051","chr3:190023493-190040215 (-) // 85.71 // q28","claudin 1","CLDN1","---","9076","603718 /// 607626","NP_066924","NM_021101","0007155 // cell adhesion // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0016338 // calcium-independent cell-cell adhesion // inferred from sequence or structural similarity /// 0045216 // cell-cell junction organization // inferred from mutant phenotype /// 0061436 // establishment of skin barrier // inferred from mutant phenotype","0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from mutant phenotype /// 0005923 // tight junction // inferred from direct assay /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation","0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from sequence or structural similarity","---","---"
"222587_s_at",1.871748638,1.340230805,1.639728765,"UP","BF699855","chr4:174089954-174245118 (+) // 96.19 // q34.1","polypeptide N-acetylgalactosaminyltransferase 7","GALNT7","ENSG00000109586 /// OTTHUMG00000160817","51809","605005","NP_059119 /// XP_005263119","NM_017423 /// XM_005263062","0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein glycosylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement","0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000772 // Ricin B lectin domain // 1.5E-24 /// IPR001173 // Glycosyltransferase 2-like // 4.7E-27"
"222717_at",-2.022902781,-1.402737419,-1.79690961,"DOWN","BF982174","chr2:192699030-192711825 (-) // 97.9 // q32.3","serum deprivation response","SDPR","ENSG00000168497 /// OTTHUMG00000154309","8436","606728","NP_004648","NM_004657","---","0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005901 // caveola // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation","0001786 // phosphatidylserine binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // traceable author statement /// 0008289 // lipid binding // inferred from electronic annotation","---","---"
"222722_at",-2.392247251,-1.428187959,-1.249223711,"DOWN","AV700059","chr9:95146248-95166915 (-) // 98.61 // q22.31","osteoglycin","OGN","ENSG00000106809 /// OTTHUMG00000020224","4969","602383","NP_054776 /// NP_148935","NM_014057 /// NM_024416 /// NM_033014","0005975 // carbohydrate metabolic process // traceable author statement /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0042340 // keratan sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from sequence or structural similarity","0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005796 // Golgi lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0043202 // lysosomal lumen // traceable author statement","0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // inferred from electronic annotation","---","IPR001611 // Leucine-rich repeat // 7.2E-6"
"222871_at",2.290493019,1.059655095,1.999371044,"UP","BF791631","chr1:205305219-205326039 (-) // 98.72 // q32.1","kelch domain containing 8A","KLHDC8A","ENSG00000162873 /// OTTHUMG00000037199","55220","614503","NP_001258792 /// NP_001258793 /// NP_001258794 /// NP_060673 /// XP_006711492","NM_001271863 /// NM_001271864 /// NM_001271865 /// NM_018203 /// XM_006711429","---","---","0005515 // protein binding // inferred from electronic annotation","---","IPR006652 // Kelch repeat type 1 // 2.4E-15 /// IPR006652 // Kelch repeat type 1 // 1.4E-11 /// IPR006652 // Kelch repeat type 1 // 5.6E-10 /// IPR006652 // Kelch repeat type 1 // 5.5E-10"
"222877_at",1.595549166,1.808014253,1.319212345,"UP","AK024680","chr2:206641875-206644438 (+) // 96.74 // q33.3","neuropilin 2","NRP2","ENSG00000118257 /// OTTHUMG00000132893","8828","602070","NP_003863 /// NP_061004 /// NP_957716 /// NP_957718 /// NP_957719 /// NP_958436 /// XP_005246990 /// XP_005246991","NM_003872 /// NM_018534 /// NM_201264 /// NM_201266 /// NM_201267 /// NM_201279 /// XM_005246933 /// XM_005246934","0001525 // angiogenesis // non-traceable author statement /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // traceable author statement /// 0007155 // cell adhesion // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // non-traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // traceable author statement /// 0021675 // nerve development // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0038084 // vascular endothelial growth factor signaling pathway // inferred from electronic annotation /// 0048010 // vascular endothelial growth factor receptor signaling pathway // traceable author statement /// 0048846 // axon extension involved in axon guidance // inferred from sequence or structural similarity /// 0050919 // negative chemotaxis // inferred from electronic annotation /// 0061549 // sympathetic ganglion development // inferred from sequence or structural similarity /// 0071526 // semaphorin-plexin signaling pathway // inferred from electronic annotation /// 0097490 // sympathetic neuron projection extension // inferred from sequence or structural similarity /// 0097491 // sympathetic neuron projection guidance // inferred from sequence or structural similarity /// 1902285 // semaphorin-plexin signaling pathway involved in neuron projection guidance // inferred from sequence or structural similarity","0002116 // semaphorin receptor complex // non-traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // non-traceable author statement /// 0030424 // axon // inferred from electronic annotation","0004872 // receptor activity // traceable author statement /// 0005021 // vascular endothelial growth factor-activated receptor activity // non-traceable author statement /// 0008201 // heparin binding // inferred from electronic annotation /// 0017154 // semaphorin receptor activity // non-traceable author statement /// 0019838 // growth factor binding // traceable author statement /// 0019955 // cytokine binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000421 // Coagulation factor 5/8 C-terminal type domain // 5.9E-30 /// IPR000421 // Coagulation factor 5/8 C-terminal type domain // 1.9E-29 /// IPR000859 // CUB domain // 3.1E-32 /// IPR000859 // CUB domain // 6.5E-33 /// IPR000998 // MAM domain // 1.9E-35 /// IPR022579 // Neuropilin-1, C-terminal // 2.6E-37"
"222921_s_at",2.32780214,1.056452116,1.689331408,"UP","AF232238","chr6:126070818-126081081 (+) // 99.52 // q22.31","hes-related family bHLH transcription factor with YRPW motif 2","HEY2","ENSG00000135547 /// OTTHUMG00000015512","23493","604674","NP_036391 /// XP_005266935 /// XP_006715491","NM_012259 /// XM_005266878 /// XM_006715428","0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0001568 // blood vessel development // inferred from electronic annotation /// 0001570 // vasculogenesis // inferred from sequence or structural similarity /// 0003150 // muscular septum morphogenesis // inferred from sequence or structural similarity /// 0003151 // outflow tract morphogenesis // inferred from sequence or structural similarity /// 0003171 // atrioventricular valve development // inferred from electronic annotation /// 0003184 // pulmonary valve morphogenesis // inferred from sequence or structural similarity /// 0003186 // tricuspid valve morphogenesis // inferred from sequence or structural similarity /// 0003195 // tricuspid valve formation // inferred from electronic annotation /// 0003199 // endocardial cushion to mesenchymal transition involved in heart valve formation // inferred from electronic annotation /// 0003208 // cardiac ventricle morphogenesis // inferred from sequence or structural similarity /// 0003214 // cardiac left ventricle morphogenesis // inferred from sequence or structural similarity /// 0003215 // cardiac right ventricle morphogenesis // inferred from sequence or structural similarity /// 0003222 // ventricular trabecula myocardium morphogenesis // inferred from electronic annotation /// 0003300 // cardiac muscle hypertrophy // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0007219 // Notch signaling pathway // inferred from sequence or structural similarity /// 0007219 // Notch signaling pathway // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0009948 // anterior/posterior axis specification // inferred from electronic annotation /// 0010460 // positive regulation of heart rate // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010621 // negative regulation of transcription by transcription factor localization // inferred from sequence or structural similarity /// 0010629 // negative regulation of gene expression // inferred from sequence or structural similarity /// 0010667 // negative regulation of cardiac muscle cell apoptotic process // inferred from electronic annotation /// 0014031 // mesenchymal cell development // inferred from sequence or structural similarity /// 0014898 // cardiac muscle hypertrophy in response to stress // inferred from electronic annotation /// 0035910 // ascending aorta morphogenesis // inferred from sequence or structural similarity /// 0035912 // dorsal aorta morphogenesis // inferred from sequence or structural similarity /// 0036304 // umbilical cord morphogenesis // inferred from sequence or structural similarity /// 0045165 // cell fate commitment // inferred from electronic annotation /// 0045607 // regulation of auditory receptor cell differentiation // inferred from electronic annotation /// 0045746 // negative regulation of Notch signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0051145 // smooth muscle cell differentiation // non-traceable author statement /// 0055015 // ventricular cardiac muscle cell development // inferred from sequence or structural similarity /// 0060045 // positive regulation of cardiac muscle cell proliferation // inferred from electronic annotation /// 0060317 // cardiac epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0060347 // heart trabecula formation // inferred from electronic annotation /// 0060411 // cardiac septum morphogenesis // inferred from sequence or structural similarity /// 0060412 // ventricular septum morphogenesis // inferred from sequence or structural similarity /// 0060413 // atrial septum morphogenesis // inferred from sequence or structural similarity /// 0060633 // negative regulation of transcription initiation from RNA polymerase II promoter // inferred from direct assay /// 0060716 // labyrinthine layer blood vessel development // inferred from sequence or structural similarity /// 0060840 // artery development // inferred from electronic annotation /// 0060842 // arterial endothelial cell differentiation // inferred from sequence or structural similarity /// 0060948 // cardiac vascular smooth muscle cell development // inferred from electronic annotation /// 0060977 // coronary vasculature morphogenesis // inferred from electronic annotation /// 0061156 // pulmonary artery morphogenesis // inferred from sequence or structural similarity /// 0061314 // Notch signaling involved in heart development // inferred by curator /// 0065004 // protein-DNA complex assembly // inferred from electronic annotation /// 0090102 // cochlea development // inferred from electronic annotation /// 0097084 // vascular smooth muscle cell development // inferred from expression pattern /// 2000678 // negative regulation of transcription regulatory region DNA binding // inferred from direct assay /// 2000723 // negative regulation of cardiac vascular smooth muscle cell differentiation // inferred from sequence or structural similarity /// 2000820 // negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation // inferred from sequence or structural similarity /// 2001212 // regulation of vasculogenesis // inferred from sequence or structural similarity","0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0016580 // Sin3 complex // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from direct assay","0000983 // RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity // inferred from sequence or structural similarity /// 0000988 // protein binding transcription factor activity // inferred from direct assay /// 0001102 // RNA polymerase II activating transcription factor binding // inferred from physical interaction /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // non-traceable author statement /// 0035939 // microsatellite binding // inferred from direct assay /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046983 // protein dimerization activity // inferred from electronic annotation","---","IPR003650 // Orange // 1.6E-17 /// IPR003650 // Orange // 2.0E-17 /// IPR011598 // Myc-type, basic helix-loop-helix (bHLH) domain // 3.5E-21 /// IPR011598 // Myc-type, basic helix-loop-helix (bHLH) domain // 4.4E-21"
"222953_at",-2.396290269,-1.272850857,-1.38358323,"DOWN","BE670361","chr11:94110481-94134418 (-) // 83.3 // q21","G protein-coupled receptor 83","GPR83","ENSG00000123901 /// OTTHUMG00000167779","10888","605569","NP_057624","NM_016540","0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation","0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // traceable author statement /// 0004983 // neuropeptide Y receptor activity // inferred from electronic annotation","GPCRDB_Class_A_Rhodopsin-like // GenMAPP /// GPCRDB_Other // GenMAPP","IPR000276 // G protein-coupled receptor, rhodopsin-like // 1.7E-61 /// IPR019424 // 7TM GPCR, olfactory receptor/chemoreceptor Srsx // 9.0E-18"
"223075_s_at",-2.420404126,-1.191140677,-1.680538221,"DOWN","AL136566","chr9:133971928-133998530 (+) // 90.27 // q34.12","allograft inflammatory factor 1-like","AIF1L","ENSG00000126878 /// OTTHUMG00000020817","83543","---","NP_001172024 /// NP_001172025 /// NP_113614","NM_001002260 /// NM_001185095 /// NM_001185096 /// NM_031426 /// NR_033701","---","0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0003779 // actin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay","---","---"
"223235_s_at",-2.704294256,-2.40717871,-2.21455902,"DOWN","AB014737","chr6:168842030-169068671 (+) // 99.86 // q27","SPARC related modular calcium binding 2","SMOC2","ENSG00000112562 /// ENSG00000255905 /// OTTHUMG00000016050","64094","125400 /// 607223","NP_001159884 /// NP_071421","NM_001166412 /// NM_022138","0007165 // signal transduction // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation","0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005614 // interstitial matrix // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation","0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005539 // glycosaminoglycan binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000716 // Thyroglobulin type-1 // 5.9E-19 /// IPR000716 // Thyroglobulin type-1 // 1.3E-18 /// IPR000716 // Thyroglobulin type-1 // 6.1E-19 /// IPR000716 // Thyroglobulin type-1 // 1.3E-18 /// IPR002350 // Kazal domain // 5.2E-12 /// IPR002350 // Kazal domain // 9.0E-9 /// IPR002350 // Kazal domain // 5.3E-12 /// IPR002350 // Kazal domain // 9.3E-9 /// IPR019577 // SPARC/Testican, calcium-binding domain // 3.2E-17 /// IPR019577 // SPARC/Testican, calcium-binding domain // 3.3E-17"
"223296_at",-1.37759994,-1.513742309,-1.444644446,"DOWN","BC004991","chr1:9599557-9642831 (+) // 96.49 // p36.22","solute carrier family 25 (pyrimidine nucleotide carrier), member 33","SLC25A33","ENSG00000171612 /// OTTHUMG00000001322","84275","610816","NP_115691 /// XP_005263560","NM_032315 /// XM_005263503","0006810 // transport // inferred from electronic annotation","0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","---","---","IPR018108 // Mitochondrial substrate/solute carrier // 3.6E-28 /// IPR018108 // Mitochondrial substrate/solute carrier // 1.0E-26 /// IPR018108 // Mitochondrial substrate/solute carrier // 9.8E-24"
"223395_at",-2.096526981,-1.321481306,-1.759537553,"DOWN","AB056106","chr3:100468181-100565393 (-) // 98.58 // q12.2","ABI family, member 3 (NESH) binding protein","ABI3BP","ENSG00000154175 /// OTTHUMG00000159094","25890","606279","NP_056244 /// XP_005247338 /// XP_005247339 /// XP_005247340 /// XP_005247341 /// XP_005247342 /// XP_005247343 /// XP_005247344 /// XP_005247345 /// XP_005247346 /// XP_005247347 /// XP_005247348 /// XP_005247350 /// XP_005247351 /// XP_005247352 /// XP_005247353 /// XP_005247354 /// XP_005247355 /// XP_005247356 /// XP_005247357 /// XP_005247358 /// XP_005247359 /// XP_005247360 /// XP_005247362 /// XP_005247363 /// XP_005247364 /// XP_005247365 /// XP_005247366 /// XP_005247367 /// XP_005247368 /// XP_005247369 /// XP_005247370 /// XP_005247371 /// XP_005247372 /// XP_005247373 /// XP_005247374 /// XP_005247375 /// XP_006713631 /// XP_006713632 /// XP_006713633 /// XP_006713634 /// XP_006713635 /// XP_006713636 /// XP_006713637 /// XP_006713638 /// XP_006713639","NM_015429 /// XM_005247281 /// XM_005247282 /// XM_005247283 /// XM_005247284 /// XM_005247285 /// XM_005247286 /// XM_005247287 /// XM_005247288 /// XM_005247289 /// XM_005247290 /// XM_005247291 /// XM_005247293 /// XM_005247294 /// XM_005247295 /// XM_005247296 /// XM_005247297 /// XM_005247298 /// XM_005247299 /// XM_005247300 /// XM_005247301 /// XM_005247302 /// XM_005247303 /// XM_005247305 /// XM_005247306 /// XM_005247307 /// XM_005247308 /// XM_005247309 /// XM_005247310 /// XM_005247311 /// XM_005247312 /// XM_005247313 /// XM_005247314 /// XM_005247315 /// XM_005247316 /// XM_005247317 /// XM_005247318 /// XM_006713568 /// XM_006713569 /// XM_006713570 /// XM_006713571 /// XM_006713572 /// XM_006713573 /// XM_006713574 /// XM_006713575 /// XM_006713576","0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation","0005576 // extracellular region // inferred from electronic annotation /// 0005614 // interstitial matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay","0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from electronic annotation /// 0005539 // glycosaminoglycan binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation","---","IPR003961 // Fibronectin, type III // 1.5E-13 /// IPR003961 // Fibronectin, type III // 8.0E-14"
"223422_s_at",-1.565302322,-1.652950498,-1.860681873,"DOWN","AI743534","chr4:86851406-86923821 (+) // 92.39 // q21.23","Rho GTPase activating protein 24","ARHGAP24","ENSG00000138639 /// OTTHUMG00000130427","83478","610586","NP_001020787 /// NP_001036134 /// NP_001274734 /// NP_112595 /// XP_005263320","NM_001025616 /// NM_001042669 /// NM_001287805 /// NM_031305 /// XM_005263263","0001525 // angiogenesis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032863 // activation of Rac GTPase activity // inferred from electronic annotation /// 0035021 // negative regulation of Rac protein signal transduction // inferred from electronic annotation /// 0035313 // wound healing, spreading of epidermal cells // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 1900028 // negative regulation of ruffle assembly // inferred from electronic annotation","0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005912 // adherens junction // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation","0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0030675 // Rac GTPase activator activity // inferred from electronic annotation","---","IPR000198 // Rho GTPase-activating protein domain // 3.4E-53 /// IPR000198 // Rho GTPase-activating protein domain // 1.4E-53 /// IPR000198 // Rho GTPase-activating protein domain // 1.4E-53 /// IPR001849 // Pleckstrin homology domain // 7.2E-22"
"223484_at",1.131856662,1.069021824,1.654712394,"UP","AF228422","chr15:45722806-45725645 (+) // 98.19 // q21.1","chromosome 15 open reading frame 48","C15orf48","ENSG00000166920 /// OTTHUMG00000131424","84419","608409","NP_115789 /// NP_922946","NM_032413 /// NM_197955","---","0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation","---","---","---"
"223503_at",2.542761919,2.226429082,2.772385991,"UP","AF255647","chr2:135213332-135214254 (-) // 99.68 // q21.3","transmembrane protein 163","TMEM163","ENSG00000152128 /// OTTHUMG00000131713","81615","---","NP_112185","NM_030923","---","0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030285 // integral component of synaptic vesicle membrane // inferred from sequence or structural similarity /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation","0008270 // zinc ion binding // inferred from sequence or structural similarity","---","---"
"223582_at",-1.59649217,-1.275508613,-1.019657974,"DOWN","AF055084","chr5:90076897-90460032 (+) // 99.94 // q14.3","G protein-coupled receptor 98","GPR98","ENSG00000164199 /// OTTHUMG00000162668","84059","602851 /// 604352 /// 605472","NP_115495","NM_032119 /// NR_003149","0007154 // cell communication // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // non-traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0016337 // single organismal cell-cell adhesion // non-traceable author statement /// 0045494 // photoreceptor cell maintenance // inferred from mutant phenotype /// 0048496 // maintenance of organ identity // inferred from mutant phenotype /// 0048839 // inner ear development // inferred from electronic annotation /// 0050877 // neurological system process // inferred from mutant phenotype /// 0050896 // response to stimulus // inferred from electronic annotation /// 0050910 // detection of mechanical stimulus involved in sensory perception of sound // inferred from electronic annotation /// 0050953 // sensory perception of light stimulus // inferred from mutant phenotype /// 0060122 // inner ear receptor stereocilium organization // inferred from electronic annotation","0002142 // stereocilia ankle link complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017022 // myosin binding // inferred from electronic annotation","GPCRDB_Other // GenMAPP","IPR000203 // GPS motif // 1.8E-10 /// IPR000203 // GPS motif // 3.8E-11 /// IPR000832 // GPCR, family 2, secretin-like // 1.7E-19 /// IPR000832 // GPCR, family 2, secretin-like // 3.1E-20 /// IPR003644 // Na-Ca exchanger/integrin-beta4 // 1.0E-9 /// IPR003644 // Na-Ca exchanger/integrin-beta4 // 1.9E-16 /// IPR003644 // Na-Ca exchanger/integrin-beta4 // 2.3E-9 /// IPR003644 // Na-Ca exchanger/integrin-beta4 // 1.6E-18 /// IPR003644 // Na-Ca exchanger/integrin-beta4 // 5.1E-14 /// IPR003644 // Na-Ca exchanger/integrin-beta4 // 3.5E-13 /// IPR003644 // Na-Ca exchanger/integrin-beta4 // 2.3E-13 /// IPR003644 // Na-Ca exchanger/integrin-beta4 // 1.6E-8 /// IPR003644 // Na-Ca exchanger/integrin-beta4 // 3.0E-15 /// IPR003644 // Na-Ca exchanger/integrin-beta4 // 3.1E-11 /// IPR003644 // Na-Ca exchanger/integrin-beta4 // 3.3E-8 /// IPR003644 // Na-Ca exchanger/integrin-beta4 // 3.9E-10 /// IPR003644 // Na-Ca exchanger/integrin-beta4 // 5.6E-19 /// IPR003644 // Na-Ca exchanger/integrin-beta4 // 1.1E-13 /// IPR003644 // Na-Ca exchanger/integrin-beta4 // 7.4E-14 /// IPR003644 // Na-Ca exchanger/integrin-beta4 // 5.2E-9 /// IPR003644 // Na-Ca exchanger/integrin-beta4 // 2.2E-14 /// IPR003644 // Na-Ca exchanger/integrin-beta4 // 1.5E-14 /// IPR003644 // Na-Ca exchanger/integrin-beta4 // 1.1E-9 /// IPR005492 // Leucine-rich glioma-inactivated , EPTP repeat // 4.6E-12"
"223614_at",1.755503713,1.46844584,1.746041726,"UP","AL136588","chr8:89044236-89046790 (-) // 92.3 // q21.3","matrix metallopeptidase 16 (membrane-inserted)","MMP16","ENSG00000156103 /// OTTHUMG00000163769","4325","602262","NP_005932","NM_005941 /// NM_022564 /// NM_032297","0006508 // proteolysis // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // traceable author statement","0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation","0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","Matrix_Metalloproteinases // GenMAPP","IPR001818 // Peptidase M10, metallopeptidase // 9.0E-60 /// IPR002477 // Peptidoglycan binding-like // 2.7E-12 /// IPR018487 // Hemopexin-like repeats // 1.7E-14 /// IPR018487 // Hemopexin-like repeats // 7.6E-16 /// IPR018487 // Hemopexin-like repeats // 1.7E-21 /// IPR018487 // Hemopexin-like repeats // 2.1E-16 /// IPR021805 // Peptidase M10A, matrix metallopeptidase, C-terminal // 6.9E-39"
"223631_s_at",1.907643718,2.314092479,1.691990835,"UP","AF213678","chr19:38794800-38795649 (+) // 90.15 // q13.2","chromosome 19 open reading frame 33","C19orf33","ENSG00000167644 /// ENSG00000267748 /// OTTHUMG00000181893 /// OTTHUMG00000181894","64073","---","NP_277055","NM_033520","0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation","0005634 // nucleus // inferred from direct assay","0003690 // double-stranded DNA binding // inferred from direct assay /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation","---","IPR002223 // Proteinase inhibitor I2, Kunitz metazoa // 3.6E-20 /// IPR002223 // Proteinase inhibitor I2, Kunitz metazoa // 3.2E-20"
"223741_s_at",-1.122942761,-1.035958186,-1.079900619,"DOWN","BC004233","chr17:72256634-72258155 (+) // 97.81 // q25.1","tweety family member 2","TTYH2","ENSG00000141540 /// OTTHUMG00000166018","94015","608855","NP_116035 /// NP_443101 /// XP_005257881","NM_032646 /// NM_052869 /// XM_005257824","0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation","0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation","0005254 // chloride channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction","---","IPR006990 // Tweety // 2.3E-182 /// IPR006990 // Tweety // 9.5E-54"
"224017_at",-1.991999105,-1.196871272,-1.369124586,"DOWN","AF251684","chrX:79278567-79287268 (+) // 99.38 // q21.1","T-box 22","TBX22","ENSG00000122145 /// OTTHUMG00000021901","50945","300307 /// 302905 /// 303400","NP_001103348 /// NP_001103349 /// NP_058650 /// XP_005262193 /// XP_005262194 /// XP_005262195 /// XP_006724720 /// XP_006725480 /// XP_006725481 /// XP_006725482 /// XP_006725483","NM_001109878 /// NM_001109879 /// NM_016954 /// XM_005262136 /// XM_005262137 /// XM_005262138 /// XM_006724657 /// XM_006725417 /// XM_006725418 /// XM_006725419 /// XM_006725420 /// XR_430822","0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay","0005634 // nucleus // inferred from direct assay","0003677 // DNA binding // inferred from direct assay /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement","---","IPR001699 // Transcription factor, T-box // 1.0E-84 /// IPR001699 // Transcription factor, T-box // 6.5E-69"
"224027_at",-1.676382886,-1.375433783,-1.187721727,"DOWN","AF110384","chr5:43376757-43412472 (-) // 41.44 // p12","chemokine (C-C motif) ligand 28","CCL28","ENSG00000151882 /// OTTHUMG00000094811","56477","605240","NP_683513 /// XP_005248382","NM_019846 /// NM_148672 /// XM_005248325 /// XR_241706 /// XR_241707 /// XR_241708 /// XR_427660","0006935 // chemotaxis // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement","0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // traceable author statement","---","IPR001811 // Chemokine interleukin-8-like domain // 3.4E-16"
"224325_at",-1.348208327,-1.023766923,-1.226559655,"DOWN","AB043703","chr10:35927176-35930362 (-) // 86.7 // p11.21","frizzled class receptor 8 /// microRNA 4683","FZD8 /// MIR4683","ENSG00000177283 /// OTTHUMG00000017956","8325 /// 100616500","606146","NP_114072","NM_031866 /// NR_039831","0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0001944 // vasculature development // not recorded /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // not recorded /// 0007420 // brain development // not recorded /// 0008406 // gonad development // not recorded /// 0009790 // embryo development // --- /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0033077 // T cell differentiation in thymus // not recorded /// 0043507 // positive regulation of JUN kinase activity // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0060070 // canonical Wnt signaling pathway // not recorded","0005737 // cytoplasm // not recorded /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0042995 // cell projection // not recorded","0004871 // signal transducer activity // inferred from electronic annotation /// 0004888 // transmembrane signaling receptor activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017147 // Wnt-protein binding // not recorded /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042813 // Wnt-activated receptor activity // not recorded /// 0042813 // Wnt-activated receptor activity // traceable author statement","Wnt_signaling // GenMAPP","IPR000539 // Frizzled protein // 1.7E-158 /// IPR020067 // Frizzled domain // 1.4E-40"
"224374_s_at",1.816687478,1.464820118,1.054699658,"UP","AF270513","chr18:2847027-2914090 (+) // 98.63 // p11.32","elastin microfibril interfacer 2","EMILIN2","ENSG00000132205 /// OTTHUMG00000128525","84034","608928","NP_114437","NM_032048","0007155 // cell adhesion // inferred from electronic annotation","0005576 // extracellular region // inferred from direct assay /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation","0005515 // protein binding // inferred from physical interaction /// 0030023 // extracellular matrix constituent conferring elasticity // non-traceable author statement","---","IPR001073 // Complement C1q protein // 2.4E-17 /// IPR011489 // EMI domain // 1.4E-24"
"224480_s_at",-1.313342985,-1.024013879,-1.390882702,"DOWN","BC006236","chr4:84518585-84527025 (+) // 95.86 // q21.23","1-acylglycerol-3-phosphate O-acyltransferase 9","AGPAT9","ENSG00000138678 /// OTTHUMG00000130431","84803","610958","NP_001243350 /// NP_001243351 /// NP_116106 /// XP_005263371","NM_001256421 /// NM_001256422 /// NM_032717 /// XM_005263314","0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0016024 // CDP-diacylglycerol biosynthetic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // inferred from direct assay /// 0019432 // triglyceride biosynthetic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0032006 // regulation of TOR signaling // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement","0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0003841 // 1-acylglycerol-3-phosphate O-acyltransferase activity // inferred from electronic annotation /// 0004366 // glycerol-3-phosphate O-acyltransferase activity // inferred from direct assay /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation","---","IPR002123 // Phospholipid/glycerol acyltransferase // 6.7E-23"
"224762_at",1.095182188,1.102837081,1.249070331,"UP","AA872583","chr1:31886108-31907525 (+) // 95.16 // p35.2","serine incorporator 2","SERINC2","ENSG00000168528 /// OTTHUMG00000003796","347735","614549","NP_001185966 /// NP_001185967 /// NP_001185968 /// NP_061035 /// NP_849196","NM_001199037 /// NM_001199038 /// NM_001199039 /// NM_018565 /// NM_178865","0006658 // phosphatidylserine metabolic process // inferred from electronic annotation /// 0051347 // positive regulation of transferase activity // inferred from electronic annotation","0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","---","---","IPR005016 // Serine incorporator/TMS membrane protein // 6.8E-168 /// IPR005016 // Serine incorporator/TMS membrane protein // 6.3E-168 /// IPR005016 // Serine incorporator/TMS membrane protein // 6.5E-168"
"224793_s_at",1.047944238,1.226853641,1.184428393,"UP","AA604375","chr9:101912527-101915931 (+) // 94.86 // q22.33","transforming growth factor, beta receptor 1","TGFBR1","ENSG00000106799 /// OTTHUMG00000020353","7046","132800 /// 190181 /// 609192","NP_001124388 /// NP_004603 /// XP_005252207","NM_001130916 /// NM_004612 /// XM_005252150","0000186 // activation of MAPKK activity // inferred from direct assay /// 0001501 // skeletal system development // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0001822 // kidney development // inferred from sequence or structural similarity /// 0001824 // blastocyst development // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // inferred from direct assay /// 0001937 // negative regulation of endothelial cell proliferation // inferred from electronic annotation /// 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from direct assay /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // inferred from direct assay /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred by curator /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0008354 // germ cell migration // inferred from sequence or structural similarity /// 0009435 // NAD biosynthetic process // inferred from electronic annotation /// 0009790 // embryo development // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from sequence or structural similarity /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0023014 // signal transduction by phosphorylation // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030199 // collagen fibril organization // inferred from sequence or structural similarity /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // traceable author statement /// 0031396 // regulation of protein ubiquitination // inferred from direct assay /// 0032331 // negative regulation of chondrocyte differentiation // inferred from sequence or structural similarity /// 0040008 // regulation of growth // inferred from electronic annotation /// 0042060 // wound healing // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043062 // extracellular structure organization // traceable author statement /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043393 // regulation of protein binding // inferred from electronic annotation /// 0043542 // endothelial cell migration // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0048538 // thymus development // inferred from sequence or structural similarity /// 0048663 // neuron fate commitment // inferred from sequence or structural similarity /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from sequence or structural similarity /// 0048705 // skeletal system morphogenesis // inferred from sequence or structural similarity /// 0048762 // mesenchymal cell differentiation // traceable author statement /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0048870 // cell motility // inferred from mutant phenotype /// 0051272 // positive regulation of cellular component movement // inferred from mutant phenotype /// 0051491 // positive regulation of filopodium assembly // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling // inferred from direct assay /// 0060017 // parathyroid gland development // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060037 // pharyngeal system development // inferred from sequence or structural similarity /// 0060389 // pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0060391 // positive regulation of SMAD protein import into nucleus // inferred from direct assay /// 0070723 // response to cholesterol // inferred from direct assay /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from direct assay /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype","0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005923 // tight junction // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070022 // transforming growth factor beta receptor homodimeric complex // inferred by curator","0000166 // nucleotide binding // inferred from electronic annotation /// 0004514 // nicotinate-nucleotide diphosphorylase (carboxylating) activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004675 // transmembrane receptor protein serine/threonine kinase activity // inferred from electronic annotation /// 0004675 // transmembrane receptor protein serine/threonine kinase activity // inferred from direct assay /// 0004702 // receptor signaling protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005024 // transforming growth factor beta-activated receptor activity // inferred by curator /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from direct assay /// 0005024 // transforming growth factor beta-activated receptor activity // inferred from mutant phenotype /// 0005025 // transforming growth factor beta receptor activity, type I // inferred from direct assay /// 0005114 // type II transforming growth factor beta receptor binding // inferred from direct assay /// 0005114 // type II transforming growth factor beta receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from physical interaction /// 0046332 // SMAD binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050431 // transforming growth factor beta binding // inferred from direct assay /// 0050431 // transforming growth factor beta binding // inferred from mutant phenotype /// 0050431 // transforming growth factor beta binding // inferred from physical interaction /// 0070411 // I-SMAD binding // inferred from physical interaction","TGF_Beta_Signaling_Pathway // GenMAPP","IPR000472 // TGF-beta receptor/activin receptor, type I/II // 2.0E-14 /// IPR000472 // TGF-beta receptor/activin receptor, type I/II // 1.5E-14 /// IPR000719 // Protein kinase domain // 9.0E-58 /// IPR000719 // Protein kinase domain // 5.6E-58 /// IPR000719 // Protein kinase domain // 9.2E-58 /// IPR001245 // Serine-threonine/tyrosine-protein kinase catalytic domain // 4.6E-39 /// IPR001245 // Serine-threonine/tyrosine-protein kinase catalytic domain // 2.8E-39 /// IPR001245 // Serine-threonine/tyrosine-protein kinase catalytic domain // 4.7E-39 /// IPR003605 // TGF beta receptor, GS motif // 1.6E-20 /// IPR003605 // TGF beta receptor, GS motif // 2.6E-8 /// IPR003605 // TGF beta receptor, GS motif // 1.6E-20"
"225275_at",2.197155685,1.476499542,1.268551857,"UP","AA053711","chr5:83236372-83238956 (-) // 99.23 // q14.3","EGF-like repeats and discoidin I-like domains 3","EDIL3","ENSG00000164176 /// OTTHUMG00000119047","10085","606018","NP_001265571 /// NP_005702","NM_001278642 /// NM_005711","0007155 // cell adhesion // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation","0005576 // extracellular region // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005178 // integrin binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000421 // Coagulation factor 5/8 C-terminal type domain // 3.2E-33 /// IPR000421 // Coagulation factor 5/8 C-terminal type domain // 1.6E-37 /// IPR000421 // Coagulation factor 5/8 C-terminal type domain // 3.0E-33 /// IPR000421 // Coagulation factor 5/8 C-terminal type domain // 1.5E-37 /// IPR000742 // Epidermal growth factor-like domain // 7.9E-12 /// IPR000742 // Epidermal growth factor-like domain // 1.2E-11 /// IPR000742 // Epidermal growth factor-like domain // 7.7E-12 /// IPR000742 // Epidermal growth factor-like domain // 1.1E-11 /// IPR013111 // EGF-like domain, extracellular // 5.4E-7 /// IPR013111 // EGF-like domain, extracellular // 6.5E-6 /// IPR013111 // EGF-like domain, extracellular // 5.3E-7 /// IPR013111 // EGF-like domain, extracellular // 6.4E-6"
"225285_at",1.935596122,1.54295545,1.207490227,"UP","AK025615","chr12:24964296-24967742 (-) // 98.08 // p12.1","branched chain amino-acid transaminase 1, cytosolic","BCAT1","ENSG00000060982 /// OTTHUMG00000169053","586","113520","NP_001171562 /// NP_001171563 /// NP_001171564 /// NP_001171565 /// NP_005495 /// XP_005253517","NM_001178091 /// NM_001178092 /// NM_001178093 /// NM_001178094 /// NM_005504 /// XM_005253460","0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008652 // cellular amino acid biosynthetic process // inferred from electronic annotation /// 0009081 // branched-chain amino acid metabolic process // inferred from electronic annotation /// 0009082 // branched-chain amino acid biosynthetic process // inferred from electronic annotation /// 0009083 // branched-chain amino acid catabolic process // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement","0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement","0003824 // catalytic activity // inferred from electronic annotation /// 0004084 // branched-chain-amino-acid transaminase activity // not recorded /// 0008483 // transaminase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0052654 // L-leucine transaminase activity // inferred from electronic annotation /// 0052655 // L-valine transaminase activity // inferred from electronic annotation /// 0052656 // L-isoleucine transaminase activity // inferred from electronic annotation","ALANINE-VALINESYN-PWY // HumanCyc /// ILEU-DEG2-PWY // HumanCyc /// ILEUDEG-PWY // HumanCyc /// ILEUSYN-PWY // HumanCyc /// LEU-DEG2-PWY // HumanCyc /// LEUDEG-PWY // HumanCyc /// LEUSYN-PWY // HumanCyc /// VALDEG-PWY // HumanCyc /// VALSYN-PWY // HumanCyc","IPR001544 // Aminotransferase, class IV // 1.5E-26"
"225520_at",1.225260125,1.618026346,1.229849439,"UP","AL133260","chr6:151186684-151423023 (+) // 94.69 // q25.1","monofunctional C1-tetrahydrofolate synthase, mitochondrial-like /// monofunctional C1-tetrahydrofolate synthase, mitochondrial-like /// methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like","LOC100996643 /// LOC101928195 /// MTHFD1L","ENSG00000120254 /// OTTHUMG00000015828","25902 /// 100996643 /// 101928195","611427","NP_001229696 /// NP_001229697 /// NP_001229698 /// NP_056255 /// XP_003846435 /// XP_005266964 /// XP_005266967 /// XP_005266968 /// XP_005272584 /// XP_005272585 /// XP_005272587 /// XP_005272588 /// XP_005272618 /// XP_005276397 /// XP_005276398 /// XP_005276399 /// XP_005276400 /// XP_005276401 /// XP_006716972 /// XP_006716973 /// XP_006716974 /// XP_006716975 /// XP_006716979","NM_001242767 /// NM_001242768 /// NM_001242769 /// NM_015440 /// XM_003846387 /// XM_005266907 /// XM_005266910 /// XM_005266911 /// XM_005272527 /// XM_005272528 /// XM_005272530 /// XM_005272531 /// XM_005272561 /// XM_005276340 /// XM_005276341 /// XM_005276342 /// XM_005276343 /// XM_005276344 /// XM_006716909 /// XM_006716910 /// XM_006716911 /// XM_006716912 /// XM_006716916 /// XR_246692 /// XR_246693 /// XR_246694 /// XR_246695 /// XR_246710 /// XR_246711 /// XR_252557 /// XR_252558 /// XR_252559 /// XR_252560 /// XR_428483 /// XR_428484 /// XR_428506 /// XR_428507 /// XR_432413 /// XR_432414","0006730 // one-carbon metabolic process // not recorded /// 0006760 // folic acid-containing compound metabolic process // inferred from direct assay /// 0009396 // folic acid-containing compound biosynthetic process // inferred from electronic annotation /// 0015942 // formate metabolic process // inferred from direct assay /// 0035999 // tetrahydrofolate interconversion // inferred from electronic annotation /// 0046653 // tetrahydrofolate metabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation","0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0016020 // membrane // inferred from direct assay","0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004329 // formate-tetrahydrofolate ligase activity // inferred from direct assay /// 0004477 // methenyltetrahydrofolate cyclohydrolase activity // not recorded /// 0004488 // methylenetetrahydrofolate dehydrogenase (NADP+) activity // not recorded /// 0005524 // ATP binding // inferred from direct assay /// 0016874 // ligase activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay","CODH-PWY // HumanCyc /// GLYCCAT-PWY // HumanCyc /// PWY-2161 // HumanCyc /// PWY-2201 // HumanCyc /// PWY-5030 // HumanCyc","IPR000559 // Formate-tetrahydrofolate ligase, FTHFS // 5.7E-262 /// IPR020630 // Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain // 1.7E-18 /// IPR020631 // Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain // 1.3E-27"
"225567_at",-1.168861384,-1.131985161,-1.050740585,"DOWN","BE207755","chr15:40616408-40618914 (+) // 97.13 // q15.1","Homo sapiens cDNA FLJ41776 fis, clone IMR322013053. /// long intergenic non-protein coding RNA 984","AL832909 /// LINC00984","---","100505573","---","XP_006710048 /// XP_006720866 /// XP_006726629","XM_006709985 /// XM_006720803 /// XM_006726566","---","---","---","---","---"
"225571_at",-2.47411728,-2.141446372,-1.901095053,"DOWN","AA701657","chr5:38475064-38477110 (-) // 96.03 // p13.1","leukemia inhibitory factor receptor alpha","LIFR","ENSG00000113594 /// OTTHUMG00000131138","3977","151443 /// 601559","NP_001121143 /// NP_002301","NM_001127671 /// NM_002310","0007166 // cell surface receptor signaling pathway // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0034097 // response to cytokine // inferred from direct assay /// 0038165 // oncostatin-M-mediated signaling pathway // inferred from direct assay /// 0048861 // leukemia inhibitory factor signaling pathway // inferred from direct assay /// 0070120 // ciliary neurotrophic factor-mediated signaling pathway // inferred from direct assay","0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004897 // ciliary neurotrophic factor receptor activity // inferred from direct assay /// 0004923 // leukemia inhibitory factor receptor activity // inferred from direct assay /// 0004924 // oncostatin-M receptor activity // inferred from direct assay /// 0005127 // ciliary neurotrophic factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from physical interaction","---","IPR003961 // Fibronectin, type III // 7.7E-10"
"225575_at",-2.140737271,-2.334743273,-2.476015275,"DOWN","AI680541","chr5:38475064-38477110 (-) // 96.03 // p13.1","leukemia inhibitory factor receptor alpha","LIFR","ENSG00000113594 /// OTTHUMG00000131138","3977","151443 /// 601559","NP_001121143 /// NP_002301","NM_001127671 /// NM_002310","0007166 // cell surface receptor signaling pathway // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0034097 // response to cytokine // inferred from direct assay /// 0038165 // oncostatin-M-mediated signaling pathway // inferred from direct assay /// 0048861 // leukemia inhibitory factor signaling pathway // inferred from direct assay /// 0070120 // ciliary neurotrophic factor-mediated signaling pathway // inferred from direct assay","0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004897 // ciliary neurotrophic factor receptor activity // inferred from direct assay /// 0004923 // leukemia inhibitory factor receptor activity // inferred from direct assay /// 0004924 // oncostatin-M receptor activity // inferred from direct assay /// 0005127 // ciliary neurotrophic factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from physical interaction","---","IPR003961 // Fibronectin, type III // 7.7E-10"
"225646_at",2.395758987,1.940676634,1.772301221,"UP","AI246687","chr11:88059253-88070910 (-) // 94.86 // q14.2","cathepsin C","CTSC","ENSG00000109861 /// OTTHUMG00000167290","1075","170650 /// 245000 /// 245010 /// 602365","NP_001107645 /// NP_001805 /// NP_680475","NM_001114173 /// NM_001814 /// NM_148170","0001913 // T cell mediated cytotoxicity // inferred from electronic annotation /// 0006508 // proteolysis // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 1903052 // positive regulation of proteolysis involved in cellular protein catabolic process // inferred from sequence or structural similarity /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation","0005615 // extracellular space // inferred from direct assay /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005764 // lysosome // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from direct assay /// 0016505 // peptidase activator activity involved in apoptotic process // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from sequence or structural similarity /// 0031404 // chloride ion binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0043621 // protein self-association // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from sequence or structural similarity","---","IPR014882 // Cathepsin C exclusion // 3.9E-41 /// IPR014882 // Cathepsin C exclusion // 4.2E-41"
"225647_s_at",2.115118283,1.775790499,1.671078891,"UP","AI246687","chr11:88059253-88070910 (-) // 94.86 // q14.2","cathepsin C","CTSC","ENSG00000109861 /// OTTHUMG00000167290","1075","170650 /// 245000 /// 245010 /// 602365","NP_001107645 /// NP_001805 /// NP_680475","NM_001114173 /// NM_001814 /// NM_148170","0001913 // T cell mediated cytotoxicity // inferred from electronic annotation /// 0006508 // proteolysis // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 1903052 // positive regulation of proteolysis involved in cellular protein catabolic process // inferred from sequence or structural similarity /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation","0005615 // extracellular space // inferred from direct assay /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005764 // lysosome // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from direct assay /// 0016505 // peptidase activator activity involved in apoptotic process // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019902 // phosphatase binding // inferred from sequence or structural similarity /// 0031404 // chloride ion binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0043621 // protein self-association // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from sequence or structural similarity","---","IPR000668 // Peptidase C1A, papain C-terminal // 1.9E-66 /// IPR000668 // Peptidase C1A, papain C-terminal // 1.2E-16 /// IPR014882 // Cathepsin C exclusion // 8.6E-61 /// IPR014882 // Cathepsin C exclusion // 6.8E-45 /// IPR014882 // Cathepsin C exclusion // 3.9E-41 /// IPR014882 // Cathepsin C exclusion // 4.2E-41"
"225667_s_at",1.681376642,1.107798648,1.789002584,"UP","AI601101","chr2:14775441-14778337 (+) // 97.58 // p24.3","family with sequence similarity 84, member A","FAM84A","ENSG00000162981 /// OTTHUMG00000119093","151354","611234","NP_660158 /// XP_006711924","NM_145175 /// XM_006711861","---","---","---","---","IPR007053 // LRAT-like domain // 6.6E-11"
"225681_at",1.609645641,1.197908156,2.148309483,"UP","AA584310","chr8:104383731-104395221 (+) // 98.16 // q22.3","collagen triple helix repeat containing 1","CTHRC1","ENSG00000164932 /// OTTHUMG00000164887","115908","610635 /// 614266","NP_001243028 /// NP_612464","NM_001256099 /// NM_138455","0016477 // cell migration // inferred from electronic annotation /// 0032092 // positive regulation of protein binding // inferred from electronic annotation /// 0033690 // positive regulation of osteoblast proliferation // inferred from electronic annotation /// 0043932 // ossification involved in bone remodeling // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0060071 // Wnt signaling pathway, planar cell polarity pathway // inferred from electronic annotation /// 0060122 // inner ear receptor stereocilium organization // inferred from electronic annotation /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation /// 0090103 // cochlea morphogenesis // inferred from electronic annotation /// 0090177 // establishment of planar polarity involved in neural tube closure // inferred from electronic annotation","0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation","0005109 // frizzled binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0017147 // Wnt-protein binding // inferred from electronic annotation","---","IPR008160 // Collagen triple helix repeat // 1.3E-10 /// IPR008160 // Collagen triple helix repeat // 5.6E-11"
"225685_at",1.61951706,1.458553829,1.012867669,"UP","AI801777","chr2:37869024-37871210 (-) // 91.59 // p22.2","CDC42 effector protein (Rho GTPase binding) 3","CDC42EP3","ENSG00000163171 /// OTTHUMG00000100971","10602","606133","NP_001257365 /// NP_001257366 /// NP_001257367 /// NP_006440","NM_001270436 /// NM_001270437 /// NM_001270438 /// NM_006449","0007165 // signal transduction // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation","0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation","0005515 // protein binding // inferred from electronic annotation /// 0005519 // cytoskeletal regulatory protein binding // traceable author statement","---","IPR000095 // CRIB domain // 7.4E-13"
"225725_at",1.292866247,1.463117034,1.401043698,"UP","AL533234","chr3:178735014-178737263 (-) // 90.94 // q26.32","zinc finger, matrin-type 3","ZMAT3","ENSG00000172667 /// OTTHUMG00000157290","64393","606452","NP_071915 /// NP_689426 /// XP_005247763 /// XP_006713788 /// XP_006713789","NM_022470 /// NM_152240 /// XM_005247706 /// XM_006713725 /// XM_006713726","0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation","0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation","0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR022755 // Zinc finger, double-stranded RNA binding // 3.0E-11 /// IPR022755 // Zinc finger, double-stranded RNA binding // 5.7E-11 /// IPR022755 // Zinc finger, double-stranded RNA binding // 1.9E-9"
"225727_at",-1.523939746,-1.274489377,-1.034484329,"DOWN","AB033026","chr14:68000031-68056308 (+) // 96.28 // q24.1","pleckstrin homology domain containing, family H (with MyTH4 domain) member 1","PLEKHH1","ENSG00000054690 /// OTTHUMG00000171272","57475","---","NP_065766 /// XP_005267970 /// XP_005267971 /// XP_005267972 /// XP_006720278 /// XP_006720279 /// XP_006720280 /// XP_006720281 /// XP_006720282","NM_020715 /// XM_005267913 /// XM_005267914 /// XM_005267915 /// XM_006720215 /// XM_006720216 /// XM_006720217 /// XM_006720218 /// XM_006720219 /// XR_429319","---","0005856 // cytoskeleton // inferred from electronic annotation","0005543 // phospholipid binding // inferred from electronic annotation","---","IPR000857 // MyTH4 domain // 1.2E-24 /// IPR001849 // Pleckstrin homology domain // 1.3E-19 /// IPR019748 // FERM central domain // 8.3E-14"
"225728_at",-2.320861307,-1.628069212,-1.965006786,"DOWN","AI659533","chr4:186506597-186508184 (-) // 86.55 // q35.1","sorbin and SH3 domain containing 2","SORBS2","ENSG00000154556 /// OTTHUMG00000157215","8470","---","NP_001139142 /// NP_001139143 /// NP_001139144 /// NP_001139145 /// NP_001139146 /// NP_001139147 /// NP_001257700 /// NP_003594 /// NP_066547 /// XP_005263359 /// XP_005263362 /// XP_005263363 /// XP_005263364 /// XP_005263365 /// XP_005263367 /// XP_005263368 /// XP_005263369 /// XP_005263370 /// XP_006714408 /// XP_006714409 /// XP_006714410 /// XP_006714411 /// XP_006714412 /// XP_006714413 /// XP_006714414 /// XP_006714415 /// XP_006714416 /// XP_006714417 /// XP_006714418 /// XP_006714419 /// XP_006714420 /// XP_006714421 /// XP_006714422 /// XP_006714423 /// XP_006714424 /// XP_006714425 /// XP_006714426 /// XP_006714427 /// XP_006714428 /// XP_006714429 /// XP_006714430 /// XP_006714431 /// XP_006714432 /// XP_006714433 /// XP_006714434 /// XP_006714435 /// XP_006714436 /// XP_006714437 /// XP_006714438 /// XP_006714439 /// XP_006714440 /// XP_006714441 /// XP_006714442 /// XP_006714443 /// XP_006714444 /// XP_006714445 /// XP_006714446 /// XP_006714447 /// XP_006714448 /// XP_006714449 /// XP_006714450 /// XP_006714451 /// XP_006714452 /// XP_006714453","NM_001145670 /// NM_001145671 /// NM_001145672 /// NM_001145673 /// NM_001145674 /// NM_001145675 /// NM_001270771 /// NM_003603 /// NM_021069 /// XM_005263302 /// XM_005263305 /// XM_005263306 /// XM_005263307 /// XM_005263308 /// XM_005263310 /// XM_005263311 /// XM_005263312 /// XM_005263313 /// XM_006714345 /// XM_006714346 /// XM_006714347 /// XM_006714348 /// XM_006714349 /// XM_006714350 /// XM_006714351 /// XM_006714352 /// XM_006714353 /// XM_006714354 /// XM_006714355 /// XM_006714356 /// XM_006714357 /// XM_006714358 /// XM_006714359 /// XM_006714360 /// XM_006714361 /// XM_006714362 /// XM_006714363 /// XM_006714364 /// XM_006714365 /// XM_006714366 /// XM_006714367 /// XM_006714368 /// XM_006714369 /// XM_006714370 /// XM_006714371 /// XM_006714372 /// XM_006714373 /// XM_006714374 /// XM_006714375 /// XM_006714376 /// XM_006714377 /// XM_006714378 /// XM_006714379 /// XM_006714380 /// XM_006714381 /// XM_006714382 /// XM_006714383 /// XM_006714384 /// XM_006714385 /// XM_006714386 /// XM_006714387 /// XM_006714388 /// XM_006714389 /// XM_006714390","0006606 // protein import into nucleus // inferred from electronic annotation /// 0006606 // protein import into nucleus // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation","0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0030018 // Z disc // non-traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation","0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // traceable author statement /// 0008307 // structural constituent of muscle // traceable author statement /// 0008536 // Ran GTPase binding // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0042393 // histone binding // inferred from electronic annotation /// 0042393 // histone binding // inferred from sequence or structural similarity /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR001452 // SH3 domain // 3.9E-18 /// IPR001452 // SH3 domain // 7.1E-16 /// IPR001452 // SH3 domain // 1.3E-13 /// IPR001452 // SH3 domain // 2.1E-18 /// IPR001452 // SH3 domain // 3.8E-16 /// IPR001452 // SH3 domain // 6.9E-14 /// IPR001452 // SH3 domain // 3.5E-18 /// IPR001452 // SH3 domain // 6.3E-16 /// IPR001452 // SH3 domain // 1.1E-13 /// IPR003127 // Sorbin-like // 6.5E-34 /// IPR003127 // Sorbin-like // 3.5E-34 /// IPR003127 // Sorbin-like // 2.9E-23 /// IPR011511 // Variant SH3 domain // 3.2E-18 /// IPR011511 // Variant SH3 domain // 3.2E-9 /// IPR011511 // Variant SH3 domain // 2.5E-9 /// IPR011511 // Variant SH3 domain // 1.7E-18 /// IPR011511 // Variant SH3 domain // 1.7E-9 /// IPR011511 // Variant SH3 domain // 1.3E-9 /// IPR011511 // Variant SH3 domain // 2.8E-18 /// IPR011511 // Variant SH3 domain // 2.9E-9 /// IPR011511 // Variant SH3 domain // 2.2E-9"
"226034_at",2.369105372,1.87770656,1.530306381,"UP","BE222344","chr8:29190581-29192682 (-) // 91.62 // p12","dual specificity phosphatase 4","DUSP4","ENSG00000120875 /// OTTHUMG00000133395","1846","602747","NP_001385 /// NP_476499","NM_001394 /// NM_057158","0000165 // MAPK cascade // traceable author statement /// 0000188 // inactivation of MAPK activity // inferred from electronic annotation /// 0001706 // endoderm formation // not recorded /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006470 // protein dephosphorylation // not recorded /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from electronic annotation /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement","0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement","0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // not recorded /// 0008330 // protein tyrosine/threonine phosphatase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation","---","IPR000242 // Protein-tyrosine phosphatase, receptor/non-receptor type // 7.5E-10 /// IPR000340 // Dual specificity phosphatase, catalytic domain // 3.2E-48 /// IPR001763 // Rhodanese-like domain // 6.5E-14"
"226145_s_at",-1.830135942,-1.613646998,-1.179812847,"DOWN","AL157471","chr4:79428669-79465422 (+) // 97.38 // q21.21","Fraser extracellular matrix complex subunit 1","FRAS1","ENSG00000138759 /// OTTHUMG00000160856","80144","219000 /// 607830","NP_001159605 /// NP_079350 /// XP_006714377 /// XP_006714378 /// XP_006714379 /// XP_006714380","NM_001166133 /// NM_020875 /// NM_025074 /// NM_032863 /// NM_206841 /// XM_006714314 /// XM_006714315 /// XM_006714316 /// XM_006714317","0002009 // morphogenesis of an epithelium // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation","0005604 // basement membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from sequence or structural similarity /// 0061618 // sublamina densa // inferred from sequence or structural similarity","0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR003644 // Na-Ca exchanger/integrin-beta4 // 4.2E-21 /// IPR003644 // Na-Ca exchanger/integrin-beta4 // 4.8E-14 /// IPR003644 // Na-Ca exchanger/integrin-beta4 // 4.5E-15 /// IPR003644 // Na-Ca exchanger/integrin-beta4 // 2.3E-14 /// IPR003644 // Na-Ca exchanger/integrin-beta4 // 2.0E-21"
"226228_at",-1.766645967,-2.239559824,-1.901078994,"DOWN","T15657","chr18:24432009-24434596 (-) // 95.64 // q11.2","aquaporin 4","AQP4","ENSG00000171885 /// OTTHUMG00000131955","361","600308","NP_001641 /// NP_004019","NM_001650 /// NM_004028","0006810 // transport // traceable author statement /// 0006833 // water transport // traceable author statement /// 0007399 // nervous system development // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007588 // excretion // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation /// 0015670 // carbon dioxide transport // inferred from electronic annotation /// 0030104 // water homeostasis // inferred from electronic annotation /// 0042538 // hyperosmotic salinity response // inferred from electronic annotation /// 0050891 // multicellular organismal water homeostasis // inferred from expression pattern /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070295 // renal water absorption // inferred from electronic annotation /// 0071346 // cellular response to interferon-gamma // inferred from direct assay /// 0071392 // cellular response to estradiol stimulus // inferred from electronic annotation","0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0030315 // T-tubule // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation","0005215 // transporter activity // inferred from electronic annotation /// 0005372 // water transmembrane transporter activity // traceable author statement /// 0015250 // water channel activity // not recorded /// 0015288 // porin activity // inferred from electronic annotation","---","IPR000425 // Major intrinsic protein // 3.2E-76"
"226237_at",1.116965486,1.240528818,1.490801977,"UP","AL359062","chr3:99516304-99518060 (+) // 89.01 // q12.1","collagen, type VIII, alpha 1","COL8A1","ENSG00000144810 /// OTTHUMG00000148669","1295","120251","NP_001841 /// NP_065084","NM_001850 /// NM_020351","0001525 // angiogenesis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0050673 // epithelial cell proliferation // inferred from electronic annotation","0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005591 // collagen type VIII trimer // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005515 // protein binding // inferred from electronic annotation","---","IPR001073 // Complement C1q protein // 1.5E-41 /// IPR008160 // Collagen triple helix repeat // 3.3E-9 /// IPR008160 // Collagen triple helix repeat // 1.6E-10 /// IPR008160 // Collagen triple helix repeat // 1.6E-9 /// IPR008160 // Collagen triple helix repeat // 9.4E-12 /// IPR008160 // Collagen triple helix repeat // 3.7E-10"
"226248_s_at",-1.84552461,-1.23910387,-1.915281835,"DOWN","AI565067","chr1:109731739-109749401 (+) // 77.9 // p13.3","KIAA1324","KIAA1324","ENSG00000116299 /// OTTHUMG00000011725","57535","611298","NP_001253977 /// NP_001271281 /// NP_001271282 /// NP_065826","NM_001267048 /// NM_001267049 /// NM_001284352 /// NM_001284353 /// NM_020775","0006914 // autophagy // inferred from electronic annotation /// 0009267 // cellular response to starvation // inferred from mutant phenotype /// 0016236 // macroautophagy // inferred from mutant phenotype /// 0044090 // positive regulation of vacuole organization // inferred from mutant phenotype /// 2000786 // positive regulation of autophagic vacuole assembly // inferred from mutant phenotype /// 2001240 // negative regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from mutant phenotype","0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0044822 // poly(A) RNA binding // inferred from direct assay","---","---"
"226279_at",2.197522803,1.440882436,1.209361332,"UP","AW471145","chr11:86520815-86777659 (+) // 83.67 // q14.2","protease, serine, 23","PRSS23","ENSG00000150687 /// OTTHUMG00000167226","11098","---","NP_001280107 /// NP_001280108 /// NP_001280109 /// NP_009104 /// XP_005273784","NM_001293178 /// NM_001293179 /// NM_001293180 /// NM_007173 /// NR_120591 /// NR_120592 /// NR_120593 /// XM_005273727 /// XR_424260 /// XR_428964 /// XR_432738","0006508 // proteolysis // inferred from electronic annotation","0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation","---","IPR001254 // Peptidase S1 // 8.7E-14"
"226492_at",-1.844875749,-1.285529691,-1.022282385,"DOWN","AL036088","chr15:48061683-48066420 (+) // 97.4 // q21.1","sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D","SEMA6D","ENSG00000137872 /// OTTHUMG00000172110","80031","609295","NP_001185928 /// NP_065909 /// NP_079242 /// NP_705869 /// NP_705870 /// NP_705871 /// NP_705872 /// XP_005254742 /// XP_005254743 /// XP_005254744 /// XP_005254745 /// XP_005254746 /// XP_005254747","NM_001198999 /// NM_020858 /// NM_024966 /// NM_153616 /// NM_153617 /// NM_153618 /// NM_153619 /// XM_005254685 /// XM_005254686 /// XM_005254687 /// XM_005254688 /// XM_005254689 /// XM_005254690","0006501 // C-terminal protein lipidation // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0014911 // positive regulation of smooth muscle cell migration // inferred from electronic annotation /// 0014912 // negative regulation of smooth muscle cell migration // inferred from electronic annotation /// 0016254 // preassembly of GPI anchor in ER membrane // traceable author statement /// 0021591 // ventricular system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement","0005737 // cytoplasm // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0030215 // semaphorin receptor binding // inferred from electronic annotation","---","IPR001627 // Sema domain // 9.4E-140 /// IPR001627 // Sema domain // 1.1E-139 /// IPR001627 // Sema domain // 9.5E-140 /// IPR001627 // Sema domain // 9.1E-140 /// IPR001627 // Sema domain // 2.3E-140 /// IPR002165 // Plexin // 3.3E-13 /// IPR002165 // Plexin // 2.6E-13 /// IPR002165 // Plexin // 2.4E-13 /// IPR002165 // Plexin // 6.5E-13 /// IPR002165 // Plexin // 1.7E-13"
"226599_at",-1.614323815,-1.140035605,-1.380704208,"DOWN","AA527080","chr4:153864247-153900823 (+) // 85.89 // q31.3","FH2 domain containing 1","FHDC1","ENSG00000137460 /// OTTHUMG00000161452","85462","---","NP_203751 /// XP_005263376 /// XP_006714456 /// XP_006714457","NM_033393 /// XM_005263319 /// XM_006714393 /// XM_006714394","---","---","---","---","IPR015425 // Formin, FH2 domain // 1.1E-101"
"226612_at",1.284474026,1.468953986,1.92626133,"UP","H17038","chr5:6448955-6492705 (+) // 91.69 // p15.31","ubiquitin-conjugating enzyme E2Q family-like 1","UBE2QL1","ENSG00000215218 /// OTTHUMG00000161683","134111","615832","NP_001138633 /// XP_005248304","NM_001145161 /// XM_005248247","0016567 // protein ubiquitination // inferred from electronic annotation","---","0000166 // nucleotide binding // inferred from electronic annotation /// 0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation","---","IPR000608 // Ubiquitin-conjugating enzyme, E2 // 2.1E-14"
"226614_s_at",-2.433534026,-2.041923272,-2.089464535,"DOWN","BE856336","chr8:11278973-11324268 (-) // 95.41 // p23.1","family with sequence similarity 167, member A","FAM167A","ENSG00000154319 /// OTTHUMG00000129361","83648","610085","NP_444509 /// XP_005272455","NM_053279 /// XM_005272398","---","---","---","---","IPR024280 // FAM167 // 1.1E-51"
"226733_at",-1.456223066,-1.039721943,-1.111609374,"DOWN","AA587884","chr1:207249862-207251161 (+) // 98.33 // q32.2","6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2","PFKFB2","ENSG00000123836 /// OTTHUMG00000036033","5208","171835","NP_001018063 /// NP_006203 /// XP_005273219 /// XP_006711444 /// XP_006711445","NM_001018053 /// NM_006212 /// XM_005273162 /// XM_006711381 /// XM_006711382","0005975 // carbohydrate metabolic process // traceable author statement /// 0006000 // fructose metabolic process // inferred from electronic annotation /// 0006003 // fructose 2,6-bisphosphate metabolic process // inferred from electronic annotation /// 0006006 // glucose metabolic process // traceable author statement /// 0006007 // glucose catabolic process // inferred from electronic annotation /// 0006089 // lactate metabolic process // inferred from electronic annotation /// 0006090 // pyruvate metabolic process // inferred from electronic annotation /// 0006096 // glycolytic process // inferred from direct assay /// 0006096 // glycolytic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0032024 // positive regulation of insulin secretion // inferred from electronic annotation /// 0033133 // positive regulation of glucokinase activity // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046835 // carbohydrate phosphorylation // inferred from direct assay /// 0046835 // carbohydrate phosphorylation // inferred from electronic annotation /// 0046835 // carbohydrate phosphorylation // traceable author statement","0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement","0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003873 // 6-phosphofructo-2-kinase activity // inferred from direct assay /// 0004331 // fructose-2,6-bisphosphate 2-phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction","---","IPR013078 // Histidine phosphatase superfamily, clade-1 // 1.4E-39 /// IPR013079 // 6-phosphofructo-2-kinase // 3.2E-107 /// IPR013641 // Chromatin associated protein KTI12 // 3.5E-9"
"226777_at",2.035184037,1.144297204,1.230825786,"UP","AA147933","chr10:127700959-127702777 (-) // 97.31 // q26.2","ADAM metallopeptidase domain 12","ADAM12","ENSG00000148848 /// OTTHUMG00000019243","8038","602714","NP_001275902 /// NP_001275903 /// NP_001275904 /// NP_003465 /// NP_067673","NM_001288973 /// NM_001288974 /// NM_001288975 /// NM_003474 /// NM_021641","0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007520 // myoblast fusion // traceable author statement","0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR001590 // Peptidase M12B, ADAM/reprolysin // 1.8E-74 /// IPR001762 // Blood coagulation inhibitor, Disintegrin // 2.7E-28 /// IPR002870 // Peptidase M12B, propeptide // 8.3E-36 /// IPR006586 // ADAM, cysteine-rich // 1.2E-37"
"226804_at",2.675126182,2.603493701,2.60782317,"UP","AI632223","chr17:66532888-66550954 (-) // 99.77 // q24.2","family with sequence similarity 20, member A","FAM20A","ENSG00000108950 /// OTTHUMG00000180152","54757","611062 /// 614253","NP_001230675 /// NP_060035 /// XP_006722021 /// XP_006722022 /// XP_006722023","NM_001243746 /// NM_017565 /// NR_027751 /// XM_006721958 /// XM_006721959 /// XM_006721960 /// XR_429905","0044691 // tooth eruption // inferred from mutant phenotype /// 0055074 // calcium ion homeostasis // inferred from mutant phenotype /// 0070166 // enamel mineralization // inferred from mutant phenotype","0005576 // extracellular region // inferred from electronic annotation /// 0005623 // cell // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay","---","---","IPR009581 // Domain of unknown function DUF1193 // 3.4E-104"
"226814_at",2.451083125,2.074096321,1.25111881,"UP","AI431730","chr3:64501329-64502542 (-) // 97.74 // p14.1","ADAM metallopeptidase with thrombospondin type 1 motif, 9","ADAMTS9","ENSG00000163638 /// OTTHUMG00000158722","56999","605421","NP_891550 /// XP_005265386","NM_182920 /// XM_005265329 /// XR_245151","0006508 // proteolysis // inferred from direct assay /// 0006516 // glycoprotein catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0045636 // positive regulation of melanocyte differentiation // inferred from electronic annotation /// 0048070 // regulation of developmental pigmentation // inferred from electronic annotation","0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from direct assay /// 0005615 // extracellular space // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from sequence or structural similarity","0004175 // endopeptidase activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000884 // Thrombospondin, type 1 repeat // 4.8E-10 /// IPR000884 // Thrombospondin, type 1 repeat // 2.7E-6 /// IPR000884 // Thrombospondin, type 1 repeat // 1.1E-6 /// IPR000884 // Thrombospondin, type 1 repeat // 1.1E-8 /// IPR000884 // Thrombospondin, type 1 repeat // 3.0E-9 /// IPR000884 // Thrombospondin, type 1 repeat // 7.8E-10 /// IPR000884 // Thrombospondin, type 1 repeat // 4.7E-8 /// IPR000884 // Thrombospondin, type 1 repeat // 6.8E-7 /// IPR000884 // Thrombospondin, type 1 repeat // 1.9E-8 /// IPR000884 // Thrombospondin, type 1 repeat // 1.6E-7 /// IPR000884 // Thrombospondin, type 1 repeat // 2.3E-8 /// IPR000884 // Thrombospondin, type 1 repeat // 3.1E-10 /// IPR000884 // Thrombospondin, type 1 repeat // 9.0E-7 /// IPR000884 // Thrombospondin, type 1 repeat // 4.9E-10 /// IPR000884 // Thrombospondin, type 1 repeat // 2.8E-6 /// IPR000884 // Thrombospondin, type 1 repeat // 1.1E-6 /// IPR000884 // Thrombospondin, type 1 repeat // 1.1E-8 /// IPR000884 // Thrombospondin, type 1 repeat // 3.1E-9 /// IPR000884 // Thrombospondin, type 1 repeat // 7.9E-10 /// IPR000884 // Thrombospondin, type 1 repeat // 4.8E-8 /// IPR000884 // Thrombospondin, type 1 repeat // 6.9E-7 /// IPR000884 // Thrombospondin, type 1 repeat // 2.0E-8 /// IPR000884 // Thrombospondin, type 1 repeat // 1.6E-7 /// IPR000884 // Thrombospondin, type 1 repeat // 2.3E-8 /// IPR000884 // Thrombospondin, type 1 repeat // 3.1E-10 /// IPR000884 // Thrombospondin, type 1 repeat // 9.1E-7 /// IPR001590 // Peptidase M12B, ADAM/reprolysin // 3.6E-25 /// IPR001590 // Peptidase M12B, ADAM/reprolysin // 3.5E-33 /// IPR002870 // Peptidase M12B, propeptide // 2.1E-36 /// IPR002870 // Peptidase M12B, propeptide // 2.2E-36 /// IPR010294 // ADAM-TS Spacer 1 // 6.2E-36 /// IPR010294 // ADAM-TS Spacer 1 // 6.3E-36 /// IPR012314 // Peptidase M12B, GON-ADAMTSs // 4.4E-87 /// IPR012314 // Peptidase M12B, GON-ADAMTSs // 4.5E-87"
"226864_at",-1.46165257,-1.068319107,-1.352068955,"DOWN","BF245954","chr8:79515459-79517502 (+) // 79.25 // q21.12","protein kinase (cAMP-dependent, catalytic) inhibitor alpha","PKIA","ENSG00000171033 /// OTTHUMG00000164618","5569","606059","NP_006814 /// NP_862822","NM_006823 /// NM_181839","0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0010389 // regulation of G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0042308 // negative regulation of protein import into nucleus // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from electronic annotation /// 2000480 // negative regulation of cAMP-dependent protein kinase activity // inferred from direct assay","0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation","0004860 // protein kinase inhibitor activity // inferred from electronic annotation /// 0004862 // cAMP-dependent protein kinase inhibitor activity // inferred from direct assay /// 0004862 // cAMP-dependent protein kinase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0034236 // protein kinase A catalytic subunit binding // inferred from physical interaction","Calcium_regulation_in_cardiac_cells // GenMAPP /// Smooth_muscle_contraction // GenMAPP","IPR004171 // cAMP-dependent protein kinase inhibitor // 4.5E-38"
"226961_at",3.99752978,3.928184887,3.646428264,"UP","AI347918","chr7:29606004-29606907 (+) // 96.03 // p14.3","proline rich 15","PRR15","ENSG00000176532 /// OTTHUMG00000128555","222171","---","NP_787083 /// XP_005249710 /// XP_005249711","NM_175887 /// XM_005249653 /// XM_005249654","0007275 // multicellular organismal development // inferred from electronic annotation","---","---","---","---"
"226980_at",1.20561937,1.35447511,1.995501513,"UP","AK001166","chr5:59892740-59940626 (-) // 92.02 // q12.1","DEP domain containing 1B","DEPDC1B","ENSG00000035499 /// OTTHUMG00000097083","55789","---","NP_001138680 /// NP_060839","NM_001145208 /// NM_018369","0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement","0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement","0005096 // GTPase activator activity // inferred from electronic annotation","---","IPR000198 // Rho GTPase-activating protein domain // 4.0E-11 /// IPR000591 // DEP domain // 3.1E-22"
"227055_at",2.690058641,2.260658463,2.225120899,"UP","AI827972","chr12:56075439-56078395 (+) // 96.88 // q13.2","methyltransferase like 7B","METTL7B","ENSG00000170439 /// OTTHUMG00000152665","196410","---","NP_689850","NM_152637","0008152 // metabolic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation","---","0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation","---","IPR004033 // UbiE/COQ5 methyltransferase // 6.4E-10 /// IPR007823 // Methyltransferase-related // 1.9E-8 /// IPR013216 // Methyltransferase type 11 // 5.7E-24 /// IPR013217 // Methyltransferase type 12 // 1.6E-18"
"227070_at",-2.098993507,-2.485602855,-1.779968308,"DOWN","W63754","chr12:104382761-104443921 (-) // 98.74 // q23.3","glycosyltransferase 8 domain containing 2","GLT8D2","ENSG00000120820 /// OTTHUMG00000170120","83468","---","NP_112592 /// XP_005269228","NM_031302 /// XM_005269171","0008152 // metabolic process // inferred from electronic annotation","0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation","---","IPR002495 // Glycosyl transferase, family 8 // 6.6E-47"
"227081_at",-1.484353868,-1.416728638,-1.942572058,"DOWN","AW299538","chr1:38031011-38032457 (+) // 98.57 // p34.3","dynein, axonemal, light intermediate chain 1","DNALI1","ENSG00000163879 /// OTTHUMG00000004222","7802","602135","NP_003453 /// XP_005271229","NM_003462 /// XM_005271172","0006928 // cellular component movement // traceable author statement /// 0007338 // single fertilization // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement","0005737 // cytoplasm // inferred from direct assay /// 0005858 // axonemal dynein complex // traceable author statement /// 0005930 // axoneme // inferred from direct assay /// 0030286 // dynein complex // inferred from electronic annotation","0003774 // motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction","---","IPR019347 // Axonemal dynein light chain // 7.2E-91"
"227088_at",1.64992999,1.978331998,2.070067081,"UP","BF221547","chr4:120415553-120417258 (-) // 90.44 // q26","phosphodiesterase 5A, cGMP-specific","PDE5A","ENSG00000138735 /// OTTHUMG00000132971","8654","603310","NP_001074 /// NP_236914 /// NP_246273","NM_001083 /// NM_033430 /// NM_033437","0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009187 // cyclic nucleotide metabolic process // non-traceable author statement /// 0010613 // positive regulation of cardiac muscle hypertrophy // inferred from electronic annotation /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0043406 // positive regulation of MAP kinase activity // inferred from electronic annotation /// 0046068 // cGMP metabolic process // inferred from electronic annotation /// 0046069 // cGMP catabolic process // inferred from direct assay /// 0046069 // cGMP catabolic process // inferred from electronic annotation /// 0055118 // negative regulation of cardiac muscle contraction // inferred from electronic annotation /// 0055119 // relaxation of cardiac muscle // inferred from electronic annotation /// 0060282 // positive regulation of oocyte development // inferred from electronic annotation","0005829 // cytosol // traceable author statement","0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004112 // cyclic-nucleotide phosphodiesterase activity // inferred from electronic annotation /// 0004114 // 3',5'-cyclic-nucleotide phosphodiesterase activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008081 // phosphoric diester hydrolase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030553 // cGMP binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0047555 // 3',5'-cyclic-GMP phosphodiesterase activity // inferred from electronic annotation","---","IPR002073 // 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain // 1.1E-73 /// IPR002073 // 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain // 9.8E-74 /// IPR003018 // GAF domain // 6.9E-20 /// IPR003018 // GAF domain // 1.2E-22 /// IPR003018 // GAF domain // 6.3E-20 /// IPR003018 // GAF domain // 1.0E-22"
"227091_at",-2.057995611,-1.391834694,-1.537437006,"DOWN","AB040938","chr7:76887729-76924524 (+) // 76.06 // q11.23","coiled-coil domain containing 146","CCDC146","ENSG00000135205 /// OTTHUMG00000162595","57639","---","NP_065930 /// XP_005250570 /// XP_005250571","NM_020879 /// XM_005250513 /// XM_005250514","---","---","---","---","---"
"227134_at",1.625616318,1.818793293,1.453093699,"UP","AI341537","chr1:27676797-27680421 (+) // 92.55 // p36.11","synaptotagmin-like 1","SYTL1","ENSG00000142765 /// OTTHUMG00000005770","84958","608042","NP_001180237 /// NP_116261 /// XP_005246078 /// XP_005246079 /// XP_006711050 /// XP_006711051 /// XP_006711052 /// XP_006711053 /// XP_006711054 /// XP_006711055","NM_001193308 /// NM_032872 /// XM_005246021 /// XM_005246022 /// XM_006710987 /// XM_006710988 /// XM_006710989 /// XM_006710990 /// XM_006710991 /// XM_006710992","0006886 // intracellular protein transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from direct assay","0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0019897 // extrinsic component of plasma membrane // inferred from sequence or structural similarity /// 0042470 // melanosome // inferred from sequence or structural similarity","0005515 // protein binding // inferred from physical interaction /// 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0042043 // neurexin family protein binding // inferred from sequence or structural similarity","---","IPR000008 // C2 domain // 1.5E-24 /// IPR000008 // C2 domain // 3.8E-16 /// IPR000008 // C2 domain // 1.5E-24 /// IPR000008 // C2 domain // 4.0E-16"
"227140_at",1.749787681,1.429372587,1.19711411,"UP","AI343467","chr7:41724711-41726779 (-) // 94.13 // p14.1","inhibin, beta A","INHBA","ENSG00000122641 /// OTTHUMG00000023574","3624","147290","NP_002183","NM_002192","0000082 // G1/S transition of mitotic cell cycle // inferred from direct assay /// 0001541 // ovarian follicle development // inferred from genetic interaction /// 0001541 // ovarian follicle development // non-traceable author statement /// 0001707 // mesoderm formation // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from genetic interaction /// 0002244 // hematopoietic progenitor cell differentiation // inferred from direct assay /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006952 // defense response // traceable author statement /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007166 // cell surface receptor signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007399 // nervous system development // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008584 // male gonad development // inferred from genetic interaction /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // inferred from direct assay /// 0030154 // cell differentiation // traceable author statement /// 0030218 // erythrocyte differentiation // non-traceable author statement /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0032270 // positive regulation of cellular protein metabolic process // inferred from direct assay /// 0032924 // activin receptor signaling pathway // inferred from direct assay /// 0035987 // endodermal cell differentiation // inferred from direct assay /// 0040007 // growth // inferred from electronic annotation /// 0042326 // negative regulation of phosphorylation // traceable author statement /// 0042476 // odontogenesis // inferred from genetic interaction /// 0042493 // response to drug // inferred from direct assay /// 0042541 // hemoglobin biosynthetic process // inferred from direct assay /// 0042701 // progesterone secretion // inferred from genetic interaction /// 0045077 // negative regulation of interferon-gamma biosynthetic process // traceable author statement /// 0045578 // negative regulation of B cell differentiation // traceable author statement /// 0045648 // positive regulation of erythrocyte differentiation // inferred from direct assay /// 0045650 // negative regulation of macrophage differentiation // traceable author statement /// 0045786 // negative regulation of cell cycle // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046880 // regulation of follicle-stimulating hormone secretion // inferred from genetic interaction /// 0046881 // positive regulation of follicle-stimulating hormone secretion // traceable author statement /// 0046882 // negative regulation of follicle-stimulating hormone secretion // non-traceable author statement /// 0048333 // mesodermal cell differentiation // inferred from electronic annotation /// 0051799 // negative regulation of hair follicle development // inferred from direct assay /// 0060021 // palate development // inferred from genetic interaction /// 0060279 // positive regulation of ovulation // inferred from sequence or structural similarity /// 0061029 // eyelid development in camera-type eye // inferred from sequence or structural similarity /// 0071372 // cellular response to follicle-stimulating hormone stimulus // inferred from electronic annotation /// 0071397 // cellular response to cholesterol // inferred from electronic annotation /// 0097191 // extrinsic apoptotic signaling pathway // inferred from direct assay /// 2001241 // positive regulation of extrinsic apoptotic signaling pathway in absence of ligand // inferred from direct assay","0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // traceable author statement /// 0043509 // activin A complex // inferred from direct assay /// 0043512 // inhibin A complex // inferred from direct assay","0005102 // receptor binding // inferred from electronic annotation /// 0005125 // cytokine activity // inferred from direct assay /// 0005179 // hormone activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008083 // growth factor activity // traceable author statement /// 0017046 // peptide hormone binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from electronic annotation /// 0070699 // type II activin receptor binding // inferred from physical interaction","TGF_Beta_Signaling_Pathway // GenMAPP","IPR001111 // Transforming growth factor-beta, N-terminal // 1.6E-21 /// IPR001839 // Transforming growth factor-beta, C-terminal // 2.2E-41"
"227143_s_at",1.588614702,1.46432434,1.364842879,"UP","AA706658","chr22:18216906-18217979 (-) // 97.98 // q11.21","BH3 interacting domain death agonist","BID","ENSG00000015475 /// OTTHUMG00000150087","637","601997","NP_001187 /// NP_001231496 /// NP_001231498 /// NP_001231499 /// NP_001231501 /// NP_932070 /// NP_932071","NM_001196 /// NM_001244567 /// NM_001244569 /// NM_001244570 /// NM_001244572 /// NM_197966 /// NM_197967","0001836 // release of cytochrome c from mitochondria // inferred from direct assay /// 0006626 // protein targeting to mitochondrion // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006919 // activation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0008625 // extrinsic apoptotic signaling pathway via death domain receptors // traceable author statement /// 0008637 // apoptotic mitochondrial changes // traceable author statement /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032461 // positive regulation of protein oligomerization // inferred from direct assay /// 0032464 // positive regulation of protein homooligomerization // inferred from direct assay /// 0034349 // glial cell apoptotic process // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042770 // signal transduction in response to DNA damage // traceable author statement /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0046902 // regulation of mitochondrial membrane permeability // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051402 // neuron apoptotic process // traceable author statement /// 0090150 // establishment of protein localization to membrane // inferred from direct assay /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from genetic interaction /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from mutant phenotype /// 0097191 // extrinsic apoptotic signaling pathway // inferred from electronic annotation /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement /// 1901030 // positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway // traceable author statement /// 1902108 // regulation of mitochondrial membrane permeability involved in apoptotic process // inferred from electronic annotation /// 2000045 // regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 2001238 // positive regulation of extrinsic apoptotic signaling pathway // inferred from mutant phenotype /// 2001244 // positive regulation of intrinsic apoptotic signaling pathway // traceable author statement","0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // traceable author statement /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // traceable author statement /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0032592 // integral component of mitochondrial membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005123 // death receptor binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation","Apoptosis // GenMAPP /// Apoptosis_GenMAPP // GenMAPP","IPR010479 // BH3 interacting // 7.4E-98 /// IPR010479 // BH3 interacting // 3.3E-98 /// IPR010479 // BH3 interacting // 3.0E-51"
"227174_at",-3.251821813,-2.19406102,-2.19382092,"DOWN","Z98443","chr15:53807359-53809471 (-) // 88.62 // q21.3","WD repeat domain 72","WDR72","ENSG00000166415 /// OTTHUMG00000131939","256764","613211 /// 613214","NP_001264105 /// NP_877435","NM_001277176 /// NM_182758 /// NR_102334 /// NR_102335 /// NR_102336","---","---","0005515 // protein binding // inferred from electronic annotation","---","IPR001680 // WD40 repeat // 5.4E-5 /// IPR001680 // WD40 repeat // 7.7E-7 /// IPR001680 // WD40 repeat // 3.0E-6 /// IPR001680 // WD40 repeat // 3.5E-8 /// IPR001680 // WD40 repeat // 2.7E-5 /// IPR001680 // WD40 repeat // 3.9E-7 /// IPR001680 // WD40 repeat // 1.5E-6 /// IPR001680 // WD40 repeat // 1.7E-8"
"227177_at",1.397887466,1.172275122,1.478838854,"UP","AL515381","chr9:100883258-100884577 (-) // 73.94 // q22.33","coronin, actin binding protein, 2A","CORO2A","ENSG00000106789 /// OTTHUMG00000020340","7464","602159","NP_003380 /// NP_438171","NM_003389 /// NM_052820","0030036 // actin cytoskeleton organization // not recorded /// 0035556 // intracellular signal transduction // traceable author statement","0015629 // actin cytoskeleton // not recorded /// 0017053 // transcriptional repressor complex // inferred from direct assay","0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0051015 // actin filament binding // not recorded","---","IPR001680 // WD40 repeat // 4.6E-10 /// IPR001680 // WD40 repeat // 1.2E-6 /// IPR001680 // WD40 repeat // 1.0E-8 /// IPR015048 // Domain of unknown function DUF1899 // 3.6E-36 /// IPR015049 // Domain of unknown function DUF1900 // 2.9E-58"
"227221_at",1.485111055,1.438809491,1.804879263,"UP","N36085","chr3:178737832-178739374 (-) // 97.71 // q26.32","zinc finger, matrin-type 3","ZMAT3","ENSG00000172667 /// OTTHUMG00000157290","64393","606452","NP_071915 /// NP_689426 /// XP_005247763 /// XP_006713788 /// XP_006713789","NM_022470 /// NM_152240 /// XM_005247706 /// XM_006713725 /// XM_006713726","0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation","0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation","0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR022755 // Zinc finger, double-stranded RNA binding // 3.0E-11 /// IPR022755 // Zinc finger, double-stranded RNA binding // 5.7E-11 /// IPR022755 // Zinc finger, double-stranded RNA binding // 1.9E-9"
"227240_at",2.051148919,2.765419692,3.360032349,"UP","AV703769","chr2:233743396-233744328 (-) // 90.43 // q37.1","neuronal guanine nucleotide exchange factor","NGEF","ENSG00000066248 /// OTTHUMG00000133272","25791","605991","NP_001107562 /// NP_062824","NM_001114090 /// NM_019850","0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043087 // regulation of GTPase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048013 // ephrin receptor signaling pathway // inferred from sequence or structural similarity /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0061002 // negative regulation of dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0097190 // apoptotic signaling pathway // traceable author statement","0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation","0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation","---","IPR000219 // Dbl homology (DH) domain // 3.3E-40 /// IPR001452 // SH3 domain // 2.5E-15 /// IPR011511 // Variant SH3 domain // 2.1E-11"
"227314_at",2.15169787,1.865866196,1.688968059,"UP","N95414","chr5:52388509-52390413 (+) // 66.26 // q11.2","integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)","ITGA2","ENSG00000164171 /// OTTHUMG00000131165","3673","192974 /// 614200","NP_002194","NM_002203 /// NR_073103 /// NR_073104 /// NR_073105 /// NR_073106 /// NR_073107","0001666 // response to hypoxia // inferred from electronic annotation /// 0001894 // tissue homeostasis // inferred from electronic annotation /// 0002687 // positive regulation of leukocyte migration // inferred from electronic annotation /// 0006928 // cellular component movement // inferred from electronic annotation /// 0006929 // substrate-dependent cell migration // inferred from mutant phenotype /// 0006971 // hypotonic response // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007160 // cell-matrix adhesion // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009615 // response to virus // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement /// 0010634 // positive regulation of epithelial cell migration // inferred from electronic annotation /// 0010694 // positive regulation of alkaline phosphatase activity // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0014075 // response to amine // inferred from electronic annotation /// 0014850 // response to muscle activity // inferred from electronic annotation /// 0014911 // positive regulation of smooth muscle cell migration // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030198 // extracellular matrix organization // traceable author statement /// 0030879 // mammary gland development // inferred from electronic annotation /// 0031346 // positive regulation of cell projection organization // inferred from electronic annotation /// 0031589 // cell-substrate adhesion // inferred from mutant phenotype /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0032967 // positive regulation of collagen biosynthetic process // inferred from electronic annotation /// 0033343 // positive regulation of collagen binding // inferred from electronic annotation /// 0033591 // response to L-ascorbic acid // inferred from electronic annotation /// 0033627 // cell adhesion mediated by integrin // inferred from mutant phenotype /// 0038065 // collagen-activated signaling pathway // inferred from mutant phenotype /// 0042060 // wound healing // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0043589 // skin morphogenesis // inferred from electronic annotation /// 0045184 // establishment of protein localization // inferred from electronic annotation /// 0045727 // positive regulation of translation // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred from electronic annotation /// 0045987 // positive regulation of smooth muscle contraction // inferred from electronic annotation /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0050927 // positive regulation of positive chemotaxis // inferred from electronic annotation /// 0050966 // detection of mechanical stimulus involved in sensory perception of pain // inferred from electronic annotation /// 0051971 // positive regulation of transmission of nerve impulse // inferred from electronic annotation /// 0060100 // positive regulation of phagocytosis, engulfment // inferred from electronic annotation /// 0070365 // hepatocyte differentiation // inferred from electronic annotation","0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005925 // focal adhesion // inferred from electronic annotation /// 0008305 // integrin complex // inferred from electronic annotation /// 0009279 // cell outer membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043679 // axon terminus // inferred from electronic annotation /// 0045178 // basal part of cell // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation","0001618 // virus receptor activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // traceable author statement /// 0032403 // protein complex binding // inferred from electronic annotation /// 0038064 // collagen receptor activity // inferred from mutant phenotype /// 0043236 // laminin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation","Integrin-mediated_cell_adhesion_KEGG // GenMAPP","IPR002035 // von Willebrand factor, type A // 3.9E-43 /// IPR013517 // FG-GAP repeat // 2.2E-10 /// IPR013649 // Integrin alpha-2 // 4.0E-76"
"227337_at",-1.213730458,-1.77452734,-1.047292926,"DOWN","AA886870","chr4:186317876-186321506 (+) // 96.56 // q35.1","ankyrin repeat domain 37","ANKRD37","ENSG00000186352 /// OTTHUMG00000160459","353322","---","NP_859077 /// XP_005263038","NM_181726 /// XM_005262981","---","0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation","0005515 // protein binding // inferred from electronic annotation","---","---"
"227394_at",-1.840304871,-1.504428258,-2.371704121,"DOWN","W94001","chr11:113148652-113149158 (+) // 68.01 // q23.2","neural cell adhesion molecule 1","NCAM1","ENSG00000149294 /// OTTHUMG00000167196","4684","116930","NP_000606 /// NP_001070150 /// NP_001229536 /// NP_001229537 /// NP_851996","NM_000615 /// NM_001076682 /// NM_001242607 /// NM_001242608 /// NM_181351","0001928 // regulation of exocyst assembly // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0031175 // neuron projection development // inferred from electronic annotation /// 0034109 // homotypic cell-cell adhesion // inferred from electronic annotation /// 0050850 // positive regulation of calcium-mediated signaling // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement","0000139 // Golgi membrane // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005515 // protein binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction","---","IPR003961 // Fibronectin, type III // 8.1E-16 /// IPR003961 // Fibronectin, type III // 5.2E-13 /// IPR013098 // Immunoglobulin I-set // 1.0E-21 /// IPR013098 // Immunoglobulin I-set // 1.6E-11 /// IPR013098 // Immunoglobulin I-set // 8.3E-23 /// IPR013098 // Immunoglobulin I-set // 3.0E-18 /// IPR013098 // Immunoglobulin I-set // 5.1E-15 /// IPR013106 // Immunoglobulin V-set domain // 3.0E-8 /// IPR013106 // Immunoglobulin V-set domain // 2.6E-8 /// IPR013106 // Immunoglobulin V-set domain // 1.8E-8 /// IPR013151 // Immunoglobulin // 8.9E-9 /// IPR013151 // Immunoglobulin // 9.4E-12 /// IPR013151 // Immunoglobulin // 2.2E-10 /// IPR013151 // Immunoglobulin // 3.4E-11"
"227417_at",-1.766863843,-1.408744105,-1.288387873,"DOWN","AW057543","chr1:220957425-220958152 (+) // 97.19 // q41","mitochondrial amidoxime reducing component 2","MARC2","ENSG00000117791 /// OTTHUMG00000037354","54996","614127","NP_060368 /// XP_005273225 /// XP_006711470","NM_017898 /// XM_005273168 /// XM_006711407 /// XR_247029","0008152 // metabolic process // inferred from electronic annotation /// 0042126 // nitrate metabolic process // inferred from direct assay /// 0051410 // detoxification of nitrogen compound // non-traceable author statement /// 0055114 // oxidation-reduction process // inferred from direct assay","0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0003824 // catalytic activity // inferred from electronic annotation /// 0008940 // nitrate reductase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0030151 // molybdenum ion binding // inferred from direct assay /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0043546 // molybdopterin cofactor binding // inferred from direct assay","---","IPR005302 // Molybdenum cofactor sulfurase, C-terminal // 9.6E-33 /// IPR005303 // MOSC, N-terminal beta barrel // 1.6E-39"
"227475_at",1.177648166,1.528662054,2.061866312,"UP","AI676059","chr6:1314110-1314993 (+) // 92.71 // p25.3","forkhead box Q1","FOXQ1","---","94234","612788","NP_150285","NM_033260","0000122 // negative regulation of transcription from RNA polymerase II promoter // not recorded /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // not recorded /// 0007389 // pattern specification process // not recorded /// 0009888 // tissue development // not recorded /// 0031069 // hair follicle morphogenesis // inferred from electronic annotation /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // not recorded","0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // not recorded","0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity // not recorded /// 0008134 // transcription factor binding // not recorded /// 0008301 // DNA binding, bending // not recorded /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation","---","---"
"227526_at",-1.88866331,-1.529673849,-2.207641424,"DOWN","AU151222","chr11:125827205-125830001 (-) // 86.94 // q24.2","cell adhesion associated, oncogene regulated","CDON","ENSG00000064309 /// OTTHUMG00000165862","50937","608707 /// 614226","NP_001230526 /// NP_058648","NM_001243597 /// NM_016952","0001708 // cell fate specification // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0002088 // lens development in camera-type eye // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007224 // smoothened signaling pathway // inferred from electronic annotation /// 0007520 // myoblast fusion // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from electronic annotation /// 0010172 // embryonic body morphogenesis // inferred from electronic annotation /// 0014816 // satellite cell differentiation // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0042692 // muscle cell differentiation // traceable author statement /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation /// 0043497 // regulation of protein heterodimerization activity // inferred from electronic annotation /// 0045664 // regulation of neuron differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048598 // embryonic morphogenesis // inferred from electronic annotation /// 0048643 // positive regulation of skeletal muscle tissue development // inferred from electronic annotation /// 0051057 // positive regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0051146 // striated muscle cell differentiation // inferred from electronic annotation /// 0051149 // positive regulation of muscle cell differentiation // traceable author statement /// 0060059 // embryonic retina morphogenesis in camera-type eye // inferred from electronic annotation /// 2000179 // positive regulation of neural precursor cell proliferation // inferred from electronic annotation","0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // traceable author statement","0005515 // protein binding // inferred from physical interaction","---","IPR003961 // Fibronectin, type III // 2.4E-13 /// IPR003961 // Fibronectin, type III // 1.8E-18 /// IPR003961 // Fibronectin, type III // 3.0E-11 /// IPR003961 // Fibronectin, type III // 1.2E-19 /// IPR003961 // Fibronectin, type III // 1.9E-12 /// IPR013098 // Immunoglobulin I-set // 1.9E-14 /// IPR013098 // Immunoglobulin I-set // 7.8E-19 /// IPR013098 // Immunoglobulin I-set // 1.4E-15 /// IPR013151 // Immunoglobulin // 3.1E-8 /// IPR013151 // Immunoglobulin // 1.1E-9 /// IPR013151 // Immunoglobulin // 6.9E-10"
"227529_s_at",-1.738483452,-1.211221872,-1.477391275,"DOWN","BF511276","chr6:151678864-151679671 (+) // 83.78 // q25.1","A kinase (PRKA) anchor protein 12","AKAP12","ENSG00000131016","9590","604698","NP_005091 /// NP_653080 /// XP_005267290 /// XP_005267291 /// XP_005267292","NM_005100 /// NM_144497 /// XM_005267233 /// XM_005267234 /// XM_005267235","0006605 // protein targeting // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0010739 // positive regulation of protein kinase A signaling // inferred from mutant phenotype /// 0030819 // positive regulation of cAMP biosynthetic process // inferred from mutant phenotype /// 0090036 // regulation of protein kinase C signaling // inferred from electronic annotation","0005737 // cytoplasm // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from electronic annotation","0005515 // protein binding // inferred from physical interaction /// 0008179 // adenylate cyclase binding // inferred from physical interaction /// 0051018 // protein kinase A binding // inferred from electronic annotation","G_Protein_Signaling // GenMAPP","IPR001573 // Protein kinase A anchoring, WSK motif // 1.0E-16 /// IPR001573 // Protein kinase A anchoring, WSK motif // 1.4E-16 /// IPR001573 // Protein kinase A anchoring, WSK motif // 9.9E-13 /// IPR018459 // RII binding domain // 2.0E-6"
"227618_at",1.7247028,1.772015662,1.767321829,"UP","AI250910","chrX:71372164-71373136 (+) // 90.4 // q13.1","---","---","---","---","---","---","---","---","---","---","---","---"
"227642_at",-3.024603498,-2.295493134,-2.36351573,"DOWN","AI928242","chr2:121974165-121974684 (-) // 92.64 // q14.2","transcription factor CP2-like 1","TFCP2L1","ENSG00000115112 /// OTTHUMG00000131443","29842","609785","NP_055368 /// XP_005263708 /// XP_005263709 /// XP_006712522","NM_014553 /// XM_005263651 /// XM_005263652 /// XM_006712459","0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0000902 // cell morphogenesis // inferred from electronic annotation /// 0002070 // epithelial cell maturation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006694 // steroid biosynthetic process // traceable author statement /// 0007028 // cytoplasm organization // inferred from electronic annotation /// 0007431 // salivary gland development // inferred from electronic annotation /// 0007565 // female pregnancy // traceable author statement /// 0008340 // determination of adult lifespan // inferred from electronic annotation /// 0045927 // positive regulation of growth // inferred from electronic annotation","0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation","0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation","---","IPR007604 // CP2 transcription factor // 4.4E-75"
"227657_at",-1.901084612,-1.465877486,-1.372324513,"DOWN","AA722069","chr4:141786724-142054616 (-) // 82.43 // q31.21","ring finger protein 150","RNF150","ENSG00000170153 /// OTTHUMG00000161380","57484","---","NP_065775 /// XP_005263207","NM_020724 /// XM_005263150","---","0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR003137 // Protease-associated domain, PA // 2.2E-11 /// IPR003137 // Protease-associated domain, PA // 1.9E-11 /// IPR018957 // Zinc finger, C3HC4 RING-type // 1.9E-11 /// IPR018957 // Zinc finger, C3HC4 RING-type // 1.6E-11 /// IPR018957 // Zinc finger, C3HC4 RING-type // 5.4E-12"
"227690_at",-1.560115717,-1.614772364,-1.584741062,"DOWN","BE502537","chr15:26788698-26791235 (-) // 97.35 // q12","gamma-aminobutyric acid (GABA) A receptor, beta 3","GABRB3","ENSG00000166206 /// OTTHUMG00000129231","2562","137192 /// 612269","NP_000805 /// NP_001178249 /// NP_001178250 /// NP_001265560 /// NP_068712","NM_000814 /// NM_001191320 /// NM_001191321 /// NM_001278631 /// NM_021912 /// NR_103801","0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060119 // inner ear receptor cell development // inferred from electronic annotation /// 0060384 // innervation // inferred from electronic annotation /// 0071420 // cellular response to histamine // inferred from direct assay /// 0090102 // cochlea development // inferred from electronic annotation /// 1901215 // negative regulation of neuron death // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation","0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 1902711 // GABA-A receptor complex // inferred from mutant phenotype /// 1902711 // GABA-A receptor complex // inferred from sequence or structural similarity","0004890 // GABA-A receptor activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0022851 // GABA-gated chloride ion channel activity // inferred from mutant phenotype /// 0022851 // GABA-gated chloride ion channel activity // inferred from sequence or structural similarity","---","IPR006029 // Neurotransmitter-gated ion-channel transmembrane domain // 1.1E-57 /// IPR006029 // Neurotransmitter-gated ion-channel transmembrane domain // 1.5E-57 /// IPR006202 // Neurotransmitter-gated ion-channel ligand-binding // 4.4E-55 /// IPR006202 // Neurotransmitter-gated ion-channel ligand-binding // 5.7E-55"
"227692_at",-1.235781375,-1.2993921,-1.080016359,"DOWN","AU153866","chr7:79847721-79848720 (+) // 92.14 // q21.11","guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1","GNAI1","ENSG00000127955 /// OTTHUMG00000023523","2770","139310","NP_001243343 /// NP_002060","NM_001256414 /// NM_002069","0006184 // GTP catabolic process // inferred from electronic annotation /// 0006906 // vesicle fusion // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from sequence or structural similarity /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // --- /// 0007188 // adenylate cyclase-modulating G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007193 // adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0043434 // response to peptide hormone // inferred from sequence or structural similarity /// 0051301 // cell division // inferred from mutant phenotype","0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005834 // heterotrimeric G-protein complex // not recorded /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0031234 // extrinsic component of cytoplasmic side of plasma membrane // not recorded /// 0042588 // zymogen granule // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // not recorded /// 0003924 // GTPase activity // inferred from reviewed computational analysis /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // not recorded /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from sequence or structural similarity /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031683 // G-protein beta/gamma-subunit complex binding // not recorded /// 0031821 // G-protein coupled serotonin receptor binding // not recorded /// 0032794 // GTPase activating protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR001019 // Guanine nucleotide binding protein (G-protein), alpha subunit // 2.0E-161 /// IPR006689 // Small GTPase superfamily, ARF/SAR type // 8.3E-17"
"227719_at",-2.225273268,-1.944533458,-1.477270067,"DOWN","AA934610","chr13:37418967-37420229 (-) // 82.27 // q13.3","SMAD family member 9","SMAD9","ENSG00000120693 /// OTTHUMG00000016740","4093","603295 /// 615342","NP_001120689 /// NP_005896 /// XP_005266458 /// XP_005266460 /// XP_005266461 /// XP_006719890","NM_001127217 /// NM_005905 /// XM_005266401 /// XM_005266403 /// XM_005266404 /// XM_006719827","0001657 // ureteric bud development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001880 // Mullerian duct regression // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0030509 // BMP signaling pathway // traceable author statement /// 0030901 // midbrain development // inferred from electronic annotation /// 0030902 // hindbrain development // inferred from electronic annotation /// 0035556 // intracellular signal transduction // traceable author statement /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation","0005622 // intracellular // traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement","0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030618 // transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation","TGF_Beta_Signaling_Pathway // GenMAPP","IPR001132 // SMAD domain, Dwarfin-type // 3.8E-81 /// IPR001132 // SMAD domain, Dwarfin-type // 3.2E-81 /// IPR003619 // MAD homology 1, Dwarfin-type // 5.1E-48 /// IPR003619 // MAD homology 1, Dwarfin-type // 4.4E-48 /// IPR019471 // Interferon regulatory factor-3 // 7.6E-10 /// IPR019471 // Interferon regulatory factor-3 // 6.6E-10"
"227753_at",-2.448338153,-1.569829365,-1.408770765,"DOWN","R26843","chr7:142982145-142984389 (+) // 89.04 // q34","transmembrane protein 139","TMEM139","ENSG00000178826 /// OTTHUMG00000152652","135932","---","NP_001229702 /// NP_001229703 /// NP_001229704 /// NP_001269805 /// NP_001269806 /// NP_699176","NM_001242773 /// NM_001242774 /// NM_001242775 /// NM_001282876 /// NM_001282877 /// NM_153345 /// NR_040003 /// NR_104250 /// NR_104251 /// NR_104252 /// NR_104253 /// NR_104254","---","0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","---","---","---"
"227760_at",-2.942427035,-2.465338626,-3.406259503,"DOWN","AL522781","chr9:38406525-38408233 (-) // 71.15 // p13.1","insulin-like growth factor binding protein-like 1","IGFBPL1","---","347252","610413","NP_001007564","NM_001007563","0001558 // regulation of cell growth // inferred from electronic annotation","0005576 // extracellular region // inferred from electronic annotation","0005520 // insulin-like growth factor binding // inferred from electronic annotation","---","---"
"227771_at",-1.712399454,-1.553935277,-1.591030207,"DOWN","AW592684","chr5:38477353-38479440 (-) // 98.04 // p13.1","leukemia inhibitory factor receptor alpha","LIFR","ENSG00000113594 /// OTTHUMG00000131138","3977","151443 /// 601559","NP_001121143 /// NP_002301","NM_001127671 /// NM_002310","0007166 // cell surface receptor signaling pathway // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0034097 // response to cytokine // inferred from direct assay /// 0038165 // oncostatin-M-mediated signaling pathway // inferred from direct assay /// 0048861 // leukemia inhibitory factor signaling pathway // inferred from direct assay /// 0070120 // ciliary neurotrophic factor-mediated signaling pathway // inferred from direct assay","0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0004896 // cytokine receptor activity // inferred from electronic annotation /// 0004897 // ciliary neurotrophic factor receptor activity // inferred from direct assay /// 0004923 // leukemia inhibitory factor receptor activity // inferred from direct assay /// 0004924 // oncostatin-M receptor activity // inferred from direct assay /// 0005127 // ciliary neurotrophic factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from physical interaction","---","IPR003961 // Fibronectin, type III // 7.7E-10"
"227830_at",-1.02792152,-1.301387089,-1.031901452,"DOWN","AI478781","chr15:26788698-26791235 (-) // 97.35 // q12","gamma-aminobutyric acid (GABA) A receptor, beta 3","GABRB3","ENSG00000166206 /// OTTHUMG00000129231","2562","137192 /// 612269","NP_000805 /// NP_001178249 /// NP_001178250 /// NP_001265560 /// NP_068712","NM_000814 /// NM_001191320 /// NM_001191321 /// NM_001278631 /// NM_021912 /// NR_103801","0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0060021 // palate development // inferred from sequence or structural similarity /// 0060119 // inner ear receptor cell development // inferred from electronic annotation /// 0060384 // innervation // inferred from electronic annotation /// 0071420 // cellular response to histamine // inferred from direct assay /// 0090102 // cochlea development // inferred from electronic annotation /// 1901215 // negative regulation of neuron death // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation","0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 1902711 // GABA-A receptor complex // inferred from mutant phenotype /// 1902711 // GABA-A receptor complex // inferred from sequence or structural similarity","0004890 // GABA-A receptor activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0022851 // GABA-gated chloride ion channel activity // inferred from mutant phenotype /// 0022851 // GABA-gated chloride ion channel activity // inferred from sequence or structural similarity","---","IPR006029 // Neurotransmitter-gated ion-channel transmembrane domain // 1.1E-57 /// IPR006029 // Neurotransmitter-gated ion-channel transmembrane domain // 1.5E-57 /// IPR006202 // Neurotransmitter-gated ion-channel ligand-binding // 4.4E-55 /// IPR006202 // Neurotransmitter-gated ion-channel ligand-binding // 5.7E-55"
"228072_at",1.455618609,2.117286051,2.27559762,"UP","AK024280","chr11:66774248-66818332 (+) // 80.14 // q13.2","synaptotagmin XII","SYT12","ENSG00000173227 /// OTTHUMG00000167101","91683","606436","NP_001171351 /// NP_808878 /// XP_006718800","NM_001177880 /// NM_177963 /// XM_006718737","0006810 // transport // inferred from electronic annotation","0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation","0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation","---","IPR000008 // C2 domain // 6.5E-10 /// IPR000008 // C2 domain // 9.2E-21"
"228080_at",-1.648819534,-1.511698856,-1.420125461,"DOWN","BE856341","chr11:111414744-111431689 (+) // 96.75 // q23.1","layilin","LAYN","ENSG00000204381 /// OTTHUMG00000166721","143903","---","NP_001245319 /// NP_001245320 /// NP_849156 /// XP_006718832 /// XP_006718833","NM_001258390 /// NM_001258391 /// NM_178834 /// XM_006718769 /// XM_006718770","---","0001726 // ruffle // inferred from sequence or structural similarity /// 0005925 // focal adhesion // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0005540 // hyaluronic acid binding // inferred from direct assay /// 0030246 // carbohydrate binding // inferred from electronic annotation","---","IPR001304 // C-type lectin // 9.8E-24 /// IPR001304 // C-type lectin // 9.8E-24 /// IPR001304 // C-type lectin // 6.0E-24 /// IPR001304 // C-type lectin // 1.2E-15 /// IPR001304 // C-type lectin // 5.5E-24"
"228108_at",-1.582655055,-1.633389546,-1.103822947,"DOWN","AW274846","chr3:160795658-160796692 (+) // 98.95 // q26.1","protein phosphatase, Mg2+/Mn2+ dependent, 1L","PPM1L","ENSG00000163590 /// OTTHUMG00000159048","151742","611931","NP_640338 /// XP_006713570","NM_139245 /// XM_006713507","0000165 // MAPK cascade // inferred from electronic annotation /// 0006470 // protein dephosphorylation // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // traceable author statement /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // inferred from electronic annotation /// 0030148 // sphingolipid biosynthetic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement","0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0003824 // catalytic activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR001932 // Protein phosphatase 2C (PP2C)-like domain // 4.4E-65"
"228241_at",-2.488787638,-1.445832902,-2.396775559,"DOWN","AI827789","chr7:16899036-16921612 (-) // 96.23 // p21.1","anterior gradient 3","AGR3","ENSG00000173467 /// OTTHUMG00000128411","155465","609482","NP_789783 /// XP_005249684","NM_176813 /// XM_005249627","---","0005576 // extracellular region // inferred from electronic annotation","0002162 // dystroglycan binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction","---","---"
"228249_at",-1.928082899,-1.730336196,-1.827916209,"DOWN","AA535128","chr11:36616056-36680822 (+) // 86.91 // p12","chromosome 11 open reading frame 74","C11orf74","ENSG00000166352 /// OTTHUMG00000166397","119710","---","NP_001263651 /// NP_001263652 /// NP_001263653 /// NP_001263654 /// NP_001263655 /// NP_001263656 /// NP_620142 /// XP_006718201","NM_001276722 /// NM_001276723 /// NM_001276724 /// NM_001276725 /// NM_001276726 /// NM_001276727 /// NM_138787 /// NR_077243 /// XM_006718138 /// XR_428839","---","---","---","---","---"
"228285_at",-2.569518445,-2.197835579,-1.818707728,"DOWN","AI989706","chr14:104498392-104519002 (+) // 97.97 // q32.33","tudor domain containing 9","TDRD9","ENSG00000156414 /// OTTHUMG00000152876","122402","---","NP_694591 /// XP_005267366 /// XP_006720082 /// XP_006720083","NM_153046 /// XM_005267309 /// XM_006720019 /// XM_006720020","0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007140 // male meiosis // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0009566 // fertilization // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031047 // gene silencing by RNA // inferred from electronic annotation /// 0034587 // piRNA metabolic process // inferred from sequence or structural similarity /// 0043046 // DNA methylation involved in gamete generation // inferred from sequence or structural similarity","0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0071547 // piP-body // inferred from sequence or structural similarity","0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation","---","IPR001650 // Helicase, C-terminal // 6.3E-16 /// IPR001650 // Helicase, C-terminal // 2.8E-16 /// IPR002999 // Tudor domain // 1.1E-18 /// IPR002999 // Tudor domain // 4.7E-19 /// IPR007502 // Helicase-associated domain // 8.3E-20 /// IPR007502 // Helicase-associated domain // 3.7E-20 /// IPR011545 // DEAD/DEAH box helicase domain // 7.9E-13"
"228407_at",-2.402241797,-1.449163983,-1.597053414,"DOWN","AI733234","chr6:35219991-35220849 (+) // 93.42 // p21.31","signal peptide, CUB domain, EGF-like 3","SCUBE3","ENSG00000146197 /// OTTHUMG00000014562","222663","614708","NP_689966 /// XP_005249000 /// XP_005249003 /// XP_005249004 /// XP_005249005","NM_152753 /// XM_005248943 /// XM_005248946 /// XM_005248947 /// XM_005248948","0051260 // protein homooligomerization // inferred from direct assay /// 0051291 // protein heterooligomerization // inferred from physical interaction","0005576 // extracellular region // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay","0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction","---","IPR000742 // Epidermal growth factor-like domain // 7.9E-10 /// IPR000859 // CUB domain // 1.3E-20 /// IPR001881 // EGF-like calcium-binding domain // 9.2E-13 /// IPR001881 // EGF-like calcium-binding domain // 2.6E-11 /// IPR001881 // EGF-like calcium-binding domain // 1.8E-11 /// IPR001881 // EGF-like calcium-binding domain // 9.8E-11 /// IPR001881 // EGF-like calcium-binding domain // 5.9E-9 /// IPR011641 // Tyrosine-protein kinase ephrin type A/B receptor-like // 8.3E-13 /// IPR011641 // Tyrosine-protein kinase ephrin type A/B receptor-like // 1.6E-16 /// IPR011641 // Tyrosine-protein kinase ephrin type A/B receptor-like // 6.0E-16"
"228502_at",-1.915503781,-1.114043535,-1.766534999,"DOWN","H88112","chrX:83315112-83318644 (-) // 98.39 // q21.1","ribosomal protein S6 kinase, 90kDa, polypeptide 6","RPS6KA6","---","27330","300303","NP_055311 /// XP_005262180","NM_014496 /// XM_005262123","0006468 // protein phosphorylation // inferred from electronic annotation /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0045992 // negative regulation of embryonic development // inferred from sequence or structural similarity /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 2000381 // negative regulation of mesoderm development // inferred from sequence or structural similarity","0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement","0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","Ribosomal_Proteins // GenMAPP","---"
"228503_at",-1.887970661,-1.376814746,-1.660895276,"DOWN","AW025023","chrX:83315112-83318644 (-) // 98.39 // q21.1","ribosomal protein S6 kinase, 90kDa, polypeptide 6","RPS6KA6","---","27330","300303","NP_055311 /// XP_005262180","NM_014496 /// XM_005262123","0006468 // protein phosphorylation // inferred from electronic annotation /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // inferred from mutant phenotype /// 0007165 // signal transduction // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0045992 // negative regulation of embryonic development // inferred from sequence or structural similarity /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 2000381 // negative regulation of mesoderm development // inferred from sequence or structural similarity","0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement","0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","Ribosomal_Proteins // GenMAPP","---"
"228546_at",-3.258582408,-2.80100496,-2.931020829,"DOWN","AW071705","chr7:154685324-154685995 (+) // 97.38 // q36.2","dipeptidyl-peptidase 6","DPP6","ENSG00000130226 /// OTTHUMG00000151511","1804","126141 /// 612956","NP_001034439 /// NP_001277181 /// NP_001277182 /// NP_001927 /// NP_570629 /// XP_006715934 /// XP_006715935","NM_001039350 /// NM_001290252 /// NM_001290253 /// NM_001936 /// NM_130797 /// XM_006715871 /// XM_006715872","0006508 // proteolysis // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0019228 // neuronal action potential // inferred from electronic annotation /// 0042391 // regulation of membrane potential // inferred from electronic annotation /// 0043266 // regulation of potassium ion transport // inferred from electronic annotation","0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0004177 // aminopeptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0008239 // dipeptidyl-peptidase activity // traceable author statement","---","IPR001375 // Peptidase S9, prolyl oligopeptidase, catalytic domain // 8.8E-42 /// IPR002469 // Peptidase S9B, dipeptidylpeptidase IV N-terminal // 1.2E-116 /// IPR011659 // WD40-like Beta Propeller // 5.8E-6"
"228570_at",-1.629590648,-1.427978011,-2.018684175,"DOWN","BF510581","chr12:108052634-108053417 (+) // 97.51 // q23.3","BTB (POZ) domain containing 11","BTBD11","ENSG00000151136 /// OTTHUMG00000150413","121551","---","NP_001017523 /// NP_001018082 /// XP_005268702","NM_001017523 /// NM_001018072 /// NM_152322 /// XM_005268645","---","0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0005515 // protein binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation","---","IPR002110 // Ankyrin repeat // 5.0E-13 /// IPR002110 // Ankyrin repeat // 3.2E-8 /// IPR002110 // Ankyrin repeat // 3.0E-9 /// IPR002110 // Ankyrin repeat // 2.6E-13 /// IPR002110 // Ankyrin repeat // 1.7E-8 /// IPR002110 // Ankyrin repeat // 1.6E-9 /// IPR013069 // BTB/POZ // 8.7E-24 /// IPR013069 // BTB/POZ // 4.0E-24"
"228579_at",1.488855657,1.053136177,2.565192318,"UP","AI656481","chr8:133133107-133133675 (-) // 98.1 // q24.22","potassium voltage-gated channel, KQT-like subfamily, member 3","KCNQ3","ENSG00000184156 /// OTTHUMG00000137472","3786","121201 /// 602232","NP_001191753 /// NP_004510 /// XP_005250970 /// XP_005250971 /// XP_006716617 /// XP_006716618","NM_001204824 /// NM_004519 /// XM_005250913 /// XM_005250914 /// XM_006716554 /// XM_006716555","0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0060081 // membrane hyperpolarization // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation","0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // traceable author statement /// 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0033268 // node of Ranvier // inferred from sequence or structural similarity /// 0043194 // axon initial segment // inferred from sequence or structural similarity","0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005249 // voltage-gated potassium channel activity // traceable author statement /// 0005251 // delayed rectifier potassium channel activity // not recorded /// 0005267 // potassium channel activity // traceable author statement","---","IPR005821 // Ion transport domain // 5.5E-25 /// IPR013099 // Two pore domain potassium channel domain // 1.2E-15 /// IPR013821 // Potassium channel, voltage dependent, KCNQ, C-terminal // 6.4E-57 /// IPR020969 // Ankyrin-G binding site // 2.6E-47"
"228585_at",3.054140209,3.017909606,2.425883665,"UP","AI301948","chr10:97636304-97637022 (+) // 82.67 // q24.1","ectonucleoside triphosphate diphosphohydrolase 1","ENTPD1","ENSG00000138185","953","601752 /// 615683","NP_001091645 /// NP_001157650 /// NP_001157651 /// NP_001157653 /// NP_001157654 /// NP_001157655 /// NP_001767 /// XP_006718139 /// XP_006718140","NM_001098175 /// NM_001164178 /// NM_001164179 /// NM_001164181 /// NM_001164182 /// NM_001164183 /// NM_001776 /// XM_006718076 /// XM_006718077","0006200 // ATP catabolic process // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0009181 // purine ribonucleoside diphosphate catabolic process // inferred from electronic annotation /// 0030168 // platelet activation // inferred from electronic annotation","0005605 // basal lamina // inferred from electronic annotation /// 0005886 // plasma membrane // non-traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017110 // nucleoside-diphosphatase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation","---","IPR000407 // Nucleoside phosphatase GDA1/CD39 // 8.0E-162 /// IPR000407 // Nucleoside phosphatase GDA1/CD39 // 2.4E-133 /// IPR000407 // Nucleoside phosphatase GDA1/CD39 // 2.3E-115"
"228667_at",-1.435122108,-1.162513206,-1.022209375,"DOWN","AI733330","chr6:161551051-161556499 (-) // 93.13 // q26","1-acylglycerol-3-phosphate O-acyltransferase 4","AGPAT4","ENSG00000026652 /// OTTHUMG00000015966","56895","614795","NP_064518 /// XP_005267109 /// XP_005267110 /// XP_005267111 /// XP_005267112 /// XP_006715575 /// XP_006715576 /// XP_006715577 /// XP_006715578","NM_001012733 /// NM_001012734 /// NM_020133 /// XM_005267052 /// XM_005267053 /// XM_005267054 /// XM_005267055 /// XM_006715512 /// XM_006715513 /// XM_006715514 /// XM_006715515","0006629 // lipid metabolic process // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006654 // phosphatidic acid biosynthetic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // non-traceable author statement /// 0016024 // CDP-diacylglycerol biosynthetic process // inferred from electronic annotation /// 0019432 // triglyceride biosynthetic process // traceable author statement /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046474 // glycerophospholipid biosynthetic process // traceable author statement","0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0003841 // 1-acylglycerol-3-phosphate O-acyltransferase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016746 // transferase activity, transferring acyl groups // inferred from electronic annotation","PWY-5667 // HumanCyc /// PWY0-1319 // HumanCyc /// TRIGLSYN-PWY // HumanCyc","IPR002123 // Phospholipid/glycerol acyltransferase // 9.8E-24"
"228708_at",1.885002847,1.085970111,1.9612362,"UP","BF438386","chr18:52560177-52562747 (+) // 90.37 // q21.2","RAB27B, member RAS oncogene family","RAB27B","ENSG00000041353 /// OTTHUMG00000132710","5874","603869","NP_004154 /// XP_005266790 /// XP_005266791 /// XP_006722581","NM_004163 /// XM_005266733 /// XM_005266734 /// XM_006722518","0006184 // GTP catabolic process // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0017157 // regulation of exocytosis // inferred from electronic annotation /// 0045921 // positive regulation of exocytosis // inferred from mutant phenotype /// 0071985 // multivesicular body sorting pathway // inferred from mutant phenotype","0005622 // intracellular // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030140 // trans-Golgi network transport vesicle // inferred from direct assay /// 0030667 // secretory granule membrane // inferred from electronic annotation /// 0032585 // multivesicular body membrane // inferred from direct assay /// 0042589 // zymogen granule membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0005525 // GTP binding // inferred from sequence or structural similarity /// 0019003 // GDP binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from physical interaction","---","IPR000795 // Elongation factor, GTP-binding domain // 7.7E-9 /// IPR001806 // Small GTPase superfamily // 2.2E-58 /// IPR006689 // Small GTPase superfamily, ARF/SAR type // 4.7E-17 /// IPR013684 // Mitochondrial Rho-like // 7.9E-20"
"228715_at",4.495351397,3.80573226,3.196342043,"UP","AV725825","chrX:117959607-117960931 (+) // 72.78 // q24","zinc finger, CCHC domain containing 12","ZCCHC12","ENSG00000174460 /// OTTHUMG00000022261","170261","300701","NP_776159","NM_173798","0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0030509 // BMP signaling pathway // not recorded","0016607 // nuclear speck // not recorded","0003676 // nucleic acid binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // not recorded /// 0046872 // metal ion binding // inferred from electronic annotation","---","---"
"228796_at",1.580155223,1.141830375,1.900832319,"UP","BE645967","chr3:131253560-131624190 (-) // 98.99 // q22.1","copine IV","CPNE4","ENSG00000196353 /// OTTHUMG00000159631","131034","604208","NP_001276041 /// NP_570720 /// NP_702907 /// XP_005247164","NM_001289112 /// NM_130808 /// NM_153429 /// XM_005247107","---","---","0005515 // protein binding // inferred from electronic annotation","---","IPR000008 // C2 domain // 1.6E-13 /// IPR000008 // C2 domain // 2.1E-15 /// IPR000008 // C2 domain // 1.6E-13 /// IPR000008 // C2 domain // 2.2E-15 /// IPR010734 // Copine // 5.3E-67 /// IPR010734 // Copine // 5.6E-67"
"228854_at",-1.530051876,-1.098300785,-1.004400085,"DOWN","AI492388","chr11:114125691-114126698 (+) // 84.57 // q23.2","---","---","---","---","---","---","---","---","---","---","---","---"
"228885_at",-1.354782338,-1.369911642,-1.345086131,"DOWN","AI862120","chr9:72833485-72841888 (+) // 98.67 // q21.12","MAM domain containing 2","MAMDC2","ENSG00000165072 /// OTTHUMG00000019990","256691","612879","NP_694999","NM_153267","0019800 // peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan // inferred from electronic annotation","0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005614 // interstitial matrix // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation","0005539 // glycosaminoglycan binding // inferred from electronic annotation","---","IPR000998 // MAM domain // 2.3E-27 /// IPR000998 // MAM domain // 4.5E-39 /// IPR000998 // MAM domain // 7.1E-34 /// IPR000998 // MAM domain // 4.4E-52"
"228956_at",-1.961923628,-1.472942974,-1.683616007,"DOWN","N22272","chr4:115597646-115599380 (+) // 91.08 // q26","UDP glycosyltransferase 8","UGT8","ENSG00000174607 /// OTTHUMG00000132915","7368","601291","NP_001121646 /// NP_003351 /// XP_006714365 /// XP_006714366","NM_001128174 /// NM_003360 /// XM_006714302 /// XM_006714303","0002175 // protein localization to paranode region of axon // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // inferred from electronic annotation /// 0006682 // galactosylceramide biosynthetic process // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007417 // central nervous system development // traceable author statement /// 0007422 // peripheral nervous system development // traceable author statement /// 0008088 // axon cargo transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030259 // lipid glycosylation // inferred from electronic annotation /// 0030913 // paranodal junction assembly // inferred from electronic annotation /// 0048812 // neuron projection morphogenesis // inferred from electronic annotation","0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0003851 // 2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity // inferred from electronic annotation /// 0008489 // UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016758 // transferase activity, transferring hexosyl groups // inferred from electronic annotation /// 0030246 // carbohydrate binding // inferred from electronic annotation","---","IPR002213 // UDP-glucuronosyl/UDP-glucosyltransferase // 5.7E-121 /// IPR007235 // Glycosyl transferase, family 28, C-terminal // 5.3E-10"
"228973_at",-2.078573249,-1.7290428,-2.109604961,"DOWN","AA057445","chr11:83166207-83166725 (-) // 78.33 // q14.1","discs, large homolog 2 (Drosophila)","DLG2","ENSG00000150672 /// OTTHUMG00000134309","1740","603583","NP_001136171 /// NP_001136172 /// NP_001136174 /// NP_001193698 /// NP_001355 /// XP_005273862 /// XP_005273863 /// XP_005273864 /// XP_005273866 /// XP_005273867 /// XP_005273868 /// XP_006718501 /// XP_006718502 /// XP_006718503","NM_001142699 /// NM_001142700 /// NM_001142702 /// NM_001206769 /// NM_001364 /// XM_005273805 /// XM_005273806 /// XM_005273807 /// XM_005273809 /// XM_005273810 /// XM_005273811 /// XM_006718438 /// XM_006718439 /// XM_006718440","0007268 // synaptic transmission // inferred from electronic annotation /// 0010923 // negative regulation of phosphatase activity // inferred from direct assay /// 0019233 // sensory perception of pain // inferred from electronic annotation /// 0046939 // nucleotide phosphorylation // traceable author statement","0005886 // plasma membrane // traceable author statement /// 0014069 // postsynaptic density // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0044224 // juxtaparanode region of axon // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation","0004385 // guanylate kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction","---","IPR001452 // SH3 domain // 1.6E-11 /// IPR001452 // SH3 domain // 2.5E-12 /// IPR001452 // SH3 domain // 1.6E-11 /// IPR001478 // PDZ domain // 6.8E-25 /// IPR001478 // PDZ domain // 6.2E-24 /// IPR001478 // PDZ domain // 2.7E-23 /// IPR001478 // PDZ domain // 7.3E-25 /// IPR001478 // PDZ domain // 6.6E-24 /// IPR001478 // PDZ domain // 2.9E-23 /// IPR008145 // Guanylate kinase/L-type calcium channel beta subunit // 9.4E-66 /// IPR008145 // Guanylate kinase/L-type calcium channel beta subunit // 6.6E-67 /// IPR008145 // Guanylate kinase/L-type calcium channel beta subunit // 1.0E-65 /// IPR011511 // Variant SH3 domain // 6.2E-13 /// IPR011511 // Variant SH3 domain // 8.0E-14 /// IPR011511 // Variant SH3 domain // 6.5E-13 /// IPR019583 // PDZ-associated domain of NMDA receptors // 2.0E-31 /// IPR019583 // PDZ-associated domain of NMDA receptors // 2.2E-31 /// IPR019590 // Membrane-associated guanylate kinase (MAGUK), PEST domain, N-terminal // 5.3E-41 /// IPR019590 // Membrane-associated guanylate kinase (MAGUK), PEST domain, N-terminal // 2.4E-28"
"229014_at",1.920347612,1.294080507,1.961394408,"UP","AW206234","chr5:92746724-92916370 (-) // 81.31 // q15","NR2F1 antisense RNA 1","NR2F1-AS1","ENSG00000237187 /// OTTHUMG00000162643","441094","---","---","NR_015369 /// NR_021490 /// NR_021491 /// NR_109818 /// NR_109819 /// NR_109820 /// NR_109821 /// NR_109822 /// NR_109823 /// NR_109824 /// NR_109825","---","---","---","---","---"
"229024_at",-1.910089171,-1.029561682,-1.031812889,"DOWN","BF056892","chr4:141782326-141782779 (-) // 66.42 // q31.21","ring finger protein 150","RNF150","ENSG00000170153 /// OTTHUMG00000161380","57484","---","NP_065775 /// XP_005263207","NM_020724 /// XM_005263150","---","0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR003137 // Protease-associated domain, PA // 2.2E-11 /// IPR018957 // Zinc finger, C3HC4 RING-type // 1.9E-11"
"229032_at",-2.575689827,-1.832183934,-3.610758133,"DOWN","BE962770","chr12:108642284-108643896 (+) // 88.35 // q23.3","WSC domain containing 2","WSCD2","ENSG00000075035 /// OTTHUMG00000169579","9671","---","NP_055468 /// XP_006719765 /// XP_006719766 /// XP_006719767","NM_014653 /// XM_006719702 /// XM_006719703 /// XM_006719704","---","0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","---","---","IPR002889 // Carbohydrate-binding WSC // 2.0E-22 /// IPR002889 // Carbohydrate-binding WSC // 5.0E-16 /// IPR002889 // Carbohydrate-binding WSC // 2.1E-22 /// IPR002889 // Carbohydrate-binding WSC // 5.3E-16"
"229070_at",1.363087429,1.684797774,1.478996655,"UP","AA470369","chr6:11713889-11714379 (-) // 61.79 // p24.1","androgen-dependent TFPI-regulating protein","ADTRP","ENSG00000111863 /// OTTHUMG00000014260","84830","614348","NP_001137420 /// NP_116133 /// XP_005249511 /// XP_005249512","NM_001143948 /// NM_032744 /// XM_005249454 /// XM_005249455","---","0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","---","---","IPR006838 // FAR-17a/AIG1-like protein // 8.8E-64"
"229073_at",-1.884562227,-1.589330638,-1.047238496,"DOWN","AA912476","chr15:55903741-55908846 (-) // 84.05 // q21.3","protogenin","PRTG","ENSG00000166450 /// OTTHUMG00000172591","283659","613261","NP_776175 /// XP_005254367 /// XP_005254368 /// XP_006720536","NM_173814 /// XM_005254310 /// XM_005254311 /// XM_006720473 /// XR_429451","0007275 // multicellular organismal development // inferred from electronic annotation","0005615 // extracellular space // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0005515 // protein binding // inferred from electronic annotation","---","IPR003961 // Fibronectin, type III // 3.1E-15 /// IPR003961 // Fibronectin, type III // 2.4E-14 /// IPR003961 // Fibronectin, type III // 1.7E-12 /// IPR003961 // Fibronectin, type III // 1.0E-14 /// IPR003961 // Fibronectin, type III // 1.6E-13 /// IPR013098 // Immunoglobulin I-set // 5.0E-16 /// IPR013098 // Immunoglobulin I-set // 1.7E-13 /// IPR013098 // Immunoglobulin I-set // 1.2E-12 /// IPR013098 // Immunoglobulin I-set // 1.8E-17 /// IPR013151 // Immunoglobulin // 8.0E-9"
"229130_at",-1.612291531,-1.439731051,-1.450044293,"DOWN","AU145323","chr4:8356823-8358443 (-) // 70.95 // p16.1","Homo sapiens cDNA FLJ11478 fis, clone HEMBA1001781. /// ---","AX746755 /// RP11-774O3.3","ENSG00000251615 /// OTTHUMG00000160053","---","---","---","---","---","---","---","---","---"
"229147_at",-2.599291353,-2.139176025,-1.535591348,"DOWN","AW070877","chr4:74437267-74438149 (-) // 22.99 // q13.3","Ras association (RalGDS/AF-6) domain family member 6","RASSF6","ENSG00000169435 /// OTTHUMG00000130007","166824","612620","NP_001257320 /// NP_001257321 /// NP_803876 /// NP_958834","NM_001270391 /// NM_001270392 /// NM_177532 /// NM_201431","0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation","---","0005515 // protein binding // inferred from physical interaction","---","IPR000159 // Ras-association // 1.8E-17"
"229160_at",-3.015464607,-2.642496293,-2.218065136,"DOWN","AI967987","chrX:105451849-105452947 (+) // 97.42 // q22.3","melanoma associated antigen (mutated) 1-like 1","MUM1L1","ENSG00000157502 /// OTTHUMG00000022146","139221","---","NP_001164491 /// NP_689636 /// XP_005262134 /// XP_005262135","NM_001171020 /// NM_152423 /// XM_005262077 /// XM_005262078","---","0070062 // extracellular vesicular exosome // inferred from direct assay","---","---","---"
"229163_at",1.66568302,1.004926982,2.414466053,"UP","N75559","chr1:20809806-20810213 (+) // 79.35 // p36.12","calcium/calmodulin-dependent protein kinase II inhibitor 1","CAMK2N1","---","55450","614986","NP_061054","NM_018584","0006469 // negative regulation of protein kinase activity // inferred from electronic annotation","0014069 // postsynaptic density // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation","0008427 // calcium-dependent protein kinase inhibitor activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation","---","---"
"229168_at",-2.307442157,-1.645494139,-1.299990025,"DOWN","AI690433","chr5:177664618-177679586 (-) // 96.75 // q35.3","collagen, type XXIII, alpha 1","COL23A1","ENSG00000050767 /// OTTHUMG00000130890","91522","610043","NP_775736 /// XP_006714996 /// XP_006714997 /// XP_006714998 /// XP_006714999","NM_173465 /// XM_006714933 /// XM_006714934 /// XM_006714935 /// XM_006714936","0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // traceable author statement","0005581 // collagen trimer // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","---","---","IPR008160 // Collagen triple helix repeat // 1.5E-12 /// IPR008160 // Collagen triple helix repeat // 7.7E-11 /// IPR008160 // Collagen triple helix repeat // 1.0E-12 /// IPR008160 // Collagen triple helix repeat // 6.3E-14 /// IPR008160 // Collagen triple helix repeat // 2.9E-13 /// IPR008160 // Collagen triple helix repeat // 1.3E-13 /// IPR008160 // Collagen triple helix repeat // 6.7E-14 /// IPR008160 // Collagen triple helix repeat // 1.1E-13 /// IPR008160 // Collagen triple helix repeat // 3.2E-12"
"229177_at",-1.906885423,-1.066018457,-1.713024988,"DOWN","AI823572","chr16:5094122-5115888 (-) // 94.62 // p13.3","chromosome 16 open reading frame 89","C16orf89","ENSG00000153446 /// OTTHUMG00000159314","146556","---","NP_001091984 /// NP_689672 /// XP_005255200","NM_001098514 /// NM_152459 /// XM_005255143","---","0005576 // extracellular region // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0042803 // protein homodimerization activity // inferred from physical interaction","---","---"
"229178_at",-1.927211233,-1.654882822,-1.138475724,"DOWN","AV699825","chr15:55903741-55908846 (-) // 84.05 // q21.3","protogenin","PRTG","ENSG00000166450 /// OTTHUMG00000172591","283659","613261","NP_776175 /// XP_005254367 /// XP_005254368 /// XP_006720536","NM_173814 /// XM_005254310 /// XM_005254311 /// XM_006720473 /// XR_429451","0007275 // multicellular organismal development // inferred from electronic annotation","0005615 // extracellular space // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0005515 // protein binding // inferred from electronic annotation","---","IPR003961 // Fibronectin, type III // 3.1E-15 /// IPR003961 // Fibronectin, type III // 2.4E-14 /// IPR003961 // Fibronectin, type III // 1.7E-12 /// IPR003961 // Fibronectin, type III // 1.0E-14 /// IPR003961 // Fibronectin, type III // 1.6E-13 /// IPR013098 // Immunoglobulin I-set // 5.0E-16 /// IPR013098 // Immunoglobulin I-set // 1.7E-13 /// IPR013098 // Immunoglobulin I-set // 1.2E-12 /// IPR013098 // Immunoglobulin I-set // 1.8E-17 /// IPR013151 // Immunoglobulin // 8.0E-9"
"229201_at",-1.294189899,-1.98655874,-1.994181824,"DOWN","AW044658","chrX:110470129-110470586 (+) // 97.23 // q23","p21 protein (Cdc42/Rac)-activated kinase 3","PAK3","ENSG00000077264 /// OTTHUMG00000022202","5063","300142 /// 300558","NP_001121638 /// NP_001121639 /// NP_001121640 /// NP_001121644 /// NP_001121645 /// NP_002569 /// XP_005262189 /// XP_005262190 /// XP_006724717 /// XP_006724718 /// XP_006724719","NM_001128166 /// NM_001128167 /// NM_001128168 /// NM_001128172 /// NM_001128173 /// NM_002578 /// XM_005262132 /// XM_005262133 /// XM_006724654 /// XM_006724655 /// XM_006724656 /// XR_244474","0000165 // MAPK cascade // inferred from direct assay /// 0000187 // activation of MAPK activity // inferred from direct assay /// 0000278 // mitotic cell cycle // not recorded /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // not recorded /// 0007409 // axonogenesis // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0016358 // dendrite development // inferred from sequence or structural similarity /// 0023014 // signal transduction by phosphorylation // not recorded /// 0030833 // regulation of actin filament polymerization // inferred from direct assay /// 0050808 // synapse organization // traceable author statement /// 0060997 // dendritic spine morphogenesis // traceable author statement","0005737 // cytoplasm // not recorded","0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004702 // receptor signaling protein serine/threonine kinase activity // not recorded /// 0004708 // MAP kinase kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051020 // GTPase binding // inferred from electronic annotation","G13_Signaling_Pathway // GenMAPP /// Integrin-mediated_cell_adhesion_KEGG // GenMAPP","IPR000095 // CRIB domain // 2.7E-26 /// IPR000719 // Protein kinase domain // 8.2E-76 /// IPR001245 // Serine-threonine/tyrosine-protein kinase catalytic domain // 2.0E-49"
"229302_at",-1.571979778,-1.326180061,-1.020233319,"DOWN","AA058832","chr2:39944567-39945101 (+) // 97.26 // p22.1","transmembrane protein 178A","TMEM178A","ENSG00000152154 /// OTTHUMG00000128591","130733","---","NP_001161431 /// NP_689603 /// XP_005264201 /// XP_005264202","NM_001167959 /// NM_152390 /// XM_005264144 /// XM_005264145","---","0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","---","---","---"
"229313_at",-1.803653429,-1.143152615,-1.309293845,"DOWN","AA843962","chr11:22304320-22304903 (+) // 80.61 // p14.3","anoctamin 5","ANO5","ENSG00000171714 /// OTTHUMG00000166051","203859","166260 /// 608662 /// 611307 /// 613319","NP_001136121 /// NP_998764 /// XP_005252877 /// XP_005252878 /// XP_005252879 /// XP_005252880","NM_001142649 /// NM_213599 /// XM_005252820 /// XM_005252821 /// XM_005252822 /// XM_005252823","0006821 // chloride transport // inferred from direct assay /// 0034220 // ion transmembrane transport // traceable author statement /// 0055085 // transmembrane transport // traceable author statement /// 1902476 // chloride transmembrane transport // inferred from direct assay","0005622 // intracellular // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0005229 // intracellular calcium activated chloride channel activity // inferred from direct assay","---","IPR007632 // Anoctamin // 2.9E-154"
"229372_at",1.617996979,1.57443204,1.612291417,"UP","AW299924","chr1:204167290-204183213 (-) // 95.79 // q32.1","golgi transport 1A","GOLT1A","ENSG00000174567 /// OTTHUMG00000036056","127845","---","NP_940849","NM_198447","0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation","0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","---","---","IPR007305 // Vesicle transport protein, Got1/SFT2-like // 1.1E-18"
"229476_s_at",2.795726161,1.753661994,2.036071739,"UP","AW272342","chr11:77774919-77779396 (+) // 81.73 // q14.1","thyroid hormone responsive","THRSP","ENSG00000151365 /// OTTHUMG00000166632","7069","601926","NP_003242","NM_003251","0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0010866 // regulation of triglyceride biosynthetic process // inferred from electronic annotation /// 0046890 // regulation of lipid biosynthetic process // inferred from sequence or structural similarity","0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity","0005515 // protein binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation","---","IPR009786 // Spot 14 family // 1.6E-58"
"229584_at",3.3637495,3.042845416,2.590184036,"UP","AK026776","chr12:40758728-40763084 (+) // 97.29 // q12","leucine-rich repeat kinase 2","LRRK2","ENSG00000188906 /// OTTHUMG00000059742","120892","607060 /// 609007","NP_940980 /// XP_005268686","NM_198578 /// XM_005268629","0000165 // MAPK cascade // inferred from direct assay /// 0000186 // activation of MAPKK activity // inferred from direct assay /// 0000187 // activation of MAPK activity // inferred from direct assay /// 0001934 // positive regulation of protein phosphorylation // inferred from mutant phenotype /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006914 // autophagy // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from mutant phenotype /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007406 // negative regulation of neuroblast proliferation // inferred from mutant phenotype /// 0007528 // neuromuscular junction development // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0008340 // determination of adult lifespan // inferred from mutant phenotype /// 0010508 // positive regulation of autophagy // inferred from mutant phenotype /// 0010508 // positive regulation of autophagy // inferred from sequence or structural similarity /// 0010942 // positive regulation of cell death // inferred from mutant phenotype /// 0014041 // regulation of neuron maturation // inferred from mutant phenotype /// 0014043 // negative regulation of neuron maturation // inferred from mutant phenotype /// 0015031 // protein transport // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from direct assay /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0018107 // peptidyl-threonine phosphorylation // inferred from mutant phenotype /// 0021772 // olfactory bulb development // inferred from mutant phenotype /// 0022028 // tangential migration from the subventricular zone to the olfactory bulb // inferred from mutant phenotype /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0032091 // negative regulation of protein binding // inferred from mutant phenotype /// 0032436 // positive regulation of proteasomal ubiquitin-dependent protein catabolic process // inferred from sequence or structural similarity /// 0034260 // negative regulation of GTPase activity // inferred from direct assay /// 0035564 // regulation of kidney size // inferred from sequence or structural similarity /// 0035640 // exploration behavior // inferred from mutant phenotype /// 0040012 // regulation of locomotion // inferred from mutant phenotype /// 0042391 // regulation of membrane potential // inferred from mutant phenotype /// 0043068 // positive regulation of programmed cell death // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from direct assay /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from mutant phenotype /// 0048312 // intracellular distribution of mitochondria // inferred from mutant phenotype /// 0048812 // neuron projection morphogenesis // inferred from mutant phenotype /// 0051900 // regulation of mitochondrial depolarization // inferred from mutant phenotype /// 0060161 // positive regulation of dopamine receptor signaling pathway // inferred from mutant phenotype /// 0061001 // regulation of dendritic spine morphogenesis // inferred from mutant phenotype /// 0061002 // negative regulation of dendritic spine morphogenesis // inferred from mutant phenotype /// 0070997 // neuron death // inferred from mutant phenotype /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 1901214 // regulation of neuron death // inferred from mutant phenotype /// 1902692 // regulation of neuroblast proliferation // inferred from mutant phenotype /// 1902803 // regulation of synaptic vesicle transport // inferred from sequence or structural similarity /// 1902823 // negative regulation of late endosome to lysosome transport // traceable author statement /// 1903125 // negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation // inferred from direct assay /// 2000172 // regulation of branching morphogenesis of a nerve // inferred from mutant phenotype /// 2000173 // negative regulation of branching morphogenesis of a nerve // inferred from mutant phenotype /// 2000300 // regulation of synaptic vesicle exocytosis // inferred from mutant phenotype","0005615 // extracellular space // inferred from direct assay /// 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // inferred from sequence or structural similarity /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005768 // endosome // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016234 // inclusion body // inferred from mutant phenotype /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from direct assay /// 0030425 // dendrite // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from sequence or structural similarity /// 0031966 // mitochondrial membrane // inferred from direct assay /// 0032473 // cytoplasmic side of mitochondrial outer membrane // inferred from direct assay /// 0032839 // dendrite cytoplasm // inferred from direct assay /// 0043005 // neuron projection // inferred from direct assay /// 0043025 // neuronal cell body // inferred from direct assay /// 0043204 // perikaryon // inferred from direct assay /// 0043204 // perikaryon // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0000149 // SNARE binding // inferred from physical interaction /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from physical interaction /// 0003779 // actin binding // inferred from physical interaction /// 0003924 // GTPase activity // inferred from direct assay /// 0004672 // protein kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004708 // MAP kinase kinase activity // inferred from direct assay /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004857 // enzyme inhibitor activity // inferred from direct assay /// 0005096 // GTPase activator activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0015631 // tubulin binding // inferred from direct assay /// 0016301 // kinase activity // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0017048 // Rho GTPase binding // inferred from physical interaction /// 0017075 // syntaxin-1 binding // inferred from physical interaction /// 0030276 // clathrin binding // inferred from physical interaction /// 0034211 // GTP-dependent protein kinase activity // inferred from direct assay /// 0034211 // GTP-dependent protein kinase activity // inferred from mutant phenotype /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0044325 // ion channel binding // inferred from physical interaction /// 0051018 // protein kinase A binding // inferred from physical interaction","---","IPR000719 // Protein kinase domain // 6.7E-47 /// IPR001245 // Serine-threonine/tyrosine-protein kinase catalytic domain // 4.1E-43 /// IPR001611 // Leucine-rich repeat // 2.7E-4 /// IPR001611 // Leucine-rich repeat // 4.9E-4 /// IPR001611 // Leucine-rich repeat // 4.6E-4 /// IPR001611 // Leucine-rich repeat // 2.2E-6 /// IPR001611 // Leucine-rich repeat // 6.6E-5 /// IPR001611 // Leucine-rich repeat // 3.9E-6 /// IPR001806 // Small GTPase superfamily // 2.1E-19 /// IPR006689 // Small GTPase superfamily, ARF/SAR type // 5.8E-8 /// IPR013684 // Mitochondrial Rho-like // 3.0E-30"
"229616_s_at",-1.232841092,-1.195413268,-1.486539639,"DOWN","AU158463","chr15:72452146-72454146 (-) // 97.55 // q23","GRAM domain containing 2","GRAMD2","ENSG00000175318 /// OTTHUMG00000172708","196996","---","NP_001012660","NM_001012642","---","0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","---","---","IPR004182 // GRAM domain // 2.8E-19"
"229687_s_at",-1.603788013,-1.249023037,-1.138716979,"DOWN","AA621763","chr11:45256170-45256665 (+) // 95.93 // p11.2","PR domain containing 11","PRDM11","---","56981","---","NP_001243624 /// NP_001243625","NM_001256695 /// NM_001256696 /// NM_020229 /// NR_046338","0032259 // methylation // inferred from electronic annotation","---","0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation","---","---"
"229778_at",-3.380196994,-2.971962365,-4.017825115,"DOWN","BE326710","chr12:21684881-21685461 (+) // 85.4 // p12.1","spexin hormone","SPX","ENSG00000134548 /// OTTHUMG00000169134","80763","---","NP_085049","NM_030572","0003084 // positive regulation of systemic arterial blood pressure // inferred from sequence or structural similarity /// 0010459 // negative regulation of heart rate // inferred from sequence or structural similarity /// 0032099 // negative regulation of appetite // inferred from sequence or structural similarity /// 0035814 // negative regulation of renal sodium excretion // inferred from sequence or structural similarity /// 0044539 // long-chain fatty acid import // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0051930 // regulation of sensory perception of pain // inferred from sequence or structural similarity","0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0030133 // transport vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay","0005184 // neuropeptide hormone activity // inferred from direct assay /// 0031765 // type 2 galanin receptor binding // inferred from direct assay /// 0031766 // type 3 galanin receptor binding // inferred from direct assay","---","---"
"229831_at",-1.836215742,-1.853926881,-1.79738169,"DOWN","BE221817","chr3:74311721-74535641 (-) // 94.15 // p12.3","contactin 3 (plasmacytoma associated)","CNTN3","ENSG00000113805 /// OTTHUMG00000158813","5067","601325","NP_065923 /// XP_005264814 /// XP_005264815 /// XP_005264816","NM_020872 /// XM_005264757 /// XM_005264758 /// XM_005264759","0007155 // cell adhesion // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation","0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation","0005515 // protein binding // inferred from electronic annotation","---","IPR003961 // Fibronectin, type III // 2.8E-20 /// IPR003961 // Fibronectin, type III // 4.8E-10 /// IPR003961 // Fibronectin, type III // 9.2E-16 /// IPR003961 // Fibronectin, type III // 5.9E-10 /// IPR013098 // Immunoglobulin I-set // 6.9E-13 /// IPR013098 // Immunoglobulin I-set // 9.4E-16 /// IPR013098 // Immunoglobulin I-set // 1.0E-17 /// IPR013098 // Immunoglobulin I-set // 1.5E-17 /// IPR013098 // Immunoglobulin I-set // 5.1E-13 /// IPR013106 // Immunoglobulin V-set domain // 4.1E-8 /// IPR013106 // Immunoglobulin V-set domain // 8.4E-11 /// IPR013106 // Immunoglobulin V-set domain // 1.5E-8 /// IPR013151 // Immunoglobulin // 3.4E-9 /// IPR013151 // Immunoglobulin // 4.3E-8"
"229839_at",-2.866707386,-1.195079902,-2.148743518,"DOWN","AI799784","chr8:27727398-27727784 (-) // 89.63 // p21.1","scavenger receptor class A, member 5 (putative)","SCARA5","ENSG00000168079 /// OTTHUMG00000132172","286133","611306","NP_776194","NM_173833","0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // inferred from sequence or structural similarity /// 0006897 // endocytosis // inferred from sequence or structural similarity /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from sequence or structural similarity /// 0010468 // regulation of gene expression // inferred from mutant phenotype /// 0030193 // regulation of blood coagulation // inferred from mutant phenotype /// 0034605 // cellular response to heat // inferred from electronic annotation /// 0034755 // iron ion transmembrane transport // inferred from sequence or structural similarity /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0070207 // protein homotrimerization // inferred from sequence or structural similarity","0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0070287 // ferritin receptor activity // inferred from sequence or structural similarity","---","IPR001190 // SRCR domain // 1.8E-34 /// IPR008160 // Collagen triple helix repeat // 1.5E-12 /// IPR008160 // Collagen triple helix repeat // 1.3E-12"
"229860_x_at",1.662794887,2.00631488,1.668006823,"UP","AI341602","chr4:2043719-2045691 (+) // 81.84 // p16.3","chromosome 4 open reading frame 48","C4orf48","ENSG00000243449 /// OTTHUMG00000154503","401115","614690","NP_001135408 /// NP_001161715","NM_001141936 /// NM_001168243","---","0005576 // extracellular region // inferred from electronic annotation","---","---","---"
"229866_at",2.028746779,1.800795489,2.200426055,"UP","AI826125","chr5:146766768-146767415 (+) // 98.18 // q32","serine/threonine kinase 32A","STK32A","ENSG00000169302 /// OTTHUMG00000163411","202374","---","NP_001106195 /// NP_001274669 /// NP_659438","NM_001112724 /// NM_001287740 /// NM_145001","0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation","---","0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000719 // Protein kinase domain // 2.3E-67 /// IPR001245 // Serine-threonine/tyrosine-protein kinase catalytic domain // 1.3E-43"
"229893_at",1.949870851,1.714646203,1.620829558,"UP","BF589413","chr9:85859536-85860466 (-) // 81.69 // q21.32","FERM domain containing 3","FRMD3","ENSG00000172159 /// OTTHUMG00000020103","257019","607619","NP_001231888 /// NP_001231889 /// NP_001231890 /// NP_001231891 /// NP_777598 /// XP_005251939","NM_001244959 /// NM_001244960 /// NM_001244961 /// NM_001244962 /// NM_174938 /// XM_005251882","---","0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation","0008092 // cytoskeletal protein binding // inferred from electronic annotation","---","IPR014847 // FERM adjacent (FA) // 1.2E-19 /// IPR018979 // FERM, N-terminal // 9.4E-25 /// IPR018980 // FERM, C-terminal PH-like domain // 3.7E-21 /// IPR019748 // FERM central domain // 4.5E-21"
"229912_at",1.473837217,1.447551929,1.843363701,"UP","AL042166","chr7:4305492-4306039 (+) // 95.46 // p22.2","sidekick cell adhesion molecule 1","SDK1","ENSG00000146555 /// OTTHUMG00000151733","221935","607216","NP_001073121 /// NP_689957","NM_001079653 /// NM_152744","0007155 // cell adhesion // inferred from electronic annotation","0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005515 // protein binding // inferred from electronic annotation","---","IPR003961 // Fibronectin, type III // 1.0E-19 /// IPR003961 // Fibronectin, type III // 4.1E-17 /// IPR003961 // Fibronectin, type III // 2.0E-10 /// IPR003961 // Fibronectin, type III // 4.2E-18 /// IPR003961 // Fibronectin, type III // 6.1E-11 /// IPR003961 // Fibronectin, type III // 1.4E-15 /// IPR003961 // Fibronectin, type III // 7.2E-15 /// IPR003961 // Fibronectin, type III // 8.8E-15 /// IPR003961 // Fibronectin, type III // 1.2E-12 /// IPR003961 // Fibronectin, type III // 1.8E-13 /// IPR003961 // Fibronectin, type III // 6.1E-21 /// IPR003961 // Fibronectin, type III // 1.3E-13 /// IPR003961 // Fibronectin, type III // 7.4E-17 /// IPR003961 // Fibronectin, type III // 4.0E-17 /// IPR003961 // Fibronectin, type III // 6.0E-11 /// IPR003961 // Fibronectin, type III // 7.1E-15 /// IPR003961 // Fibronectin, type III // 8.7E-15 /// IPR003961 // Fibronectin, type III // 1.8E-14 /// IPR003961 // Fibronectin, type III // 6.1E-21 /// IPR003961 // Fibronectin, type III // 1.3E-13 /// IPR003961 // Fibronectin, type III // 7.3E-17 /// IPR013098 // Immunoglobulin I-set // 5.3E-9 /// IPR013098 // Immunoglobulin I-set // 1.3E-12 /// IPR013098 // Immunoglobulin I-set // 6.3E-16 /// IPR013098 // Immunoglobulin I-set // 6.8E-20 /// IPR013098 // Immunoglobulin I-set // 1.1E-11 /// IPR013098 // Immunoglobulin I-set // 5.2E-9 /// IPR013098 // Immunoglobulin I-set // 1.2E-12 /// IPR013098 // Immunoglobulin I-set // 6.2E-16 /// IPR013106 // Immunoglobulin V-set domain // 7.8E-9 /// IPR013151 // Immunoglobulin // 1.2E-8 /// IPR013151 // Immunoglobulin // 2.9E-8 /// IPR013151 // Immunoglobulin // 2.8E-8"
"229927_at",1.590259989,1.411842101,1.260443529,"UP","BE222220","chr1:205350505-205389659 (-) // 80.4 // q32.1","LEM domain containing 1","LEMD1","ENSG00000186007 /// OTTHUMG00000037201","93273","610480","NP_001001552 /// NP_001185979 /// NP_001185980 /// NP_001185981 /// XP_006711695","NM_001001552 /// NM_001199050 /// NM_001199051 /// NM_001199052 /// NR_037583 /// XM_006711632","---","0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","---","---","IPR003887 // LEM domain // 5.6E-9 /// IPR003887 // LEM domain // 1.7E-18 /// IPR003887 // LEM domain // 6.2E-19 /// IPR003887 // LEM domain // 1.6E-9"
"230031_at",-1.293412018,-1.061499536,-1.36660048,"DOWN","AW052044","chr9:127997128-127997591 (-) // 76.5 // q33.3","heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)","HSPA5","ENSG00000044574 /// OTTHUMG00000020672","3309","138120","NP_005338","NM_005347","0000902 // cell morphogenesis // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006200 // ATP catabolic process // inferred from sequence or structural similarity /// 0006983 // ER overload response // inferred from electronic annotation /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0021589 // cerebellum structural organization // inferred from electronic annotation /// 0021680 // cerebellar Purkinje cell layer development // inferred from electronic annotation /// 0021762 // substantia nigra development // inferred from expression pattern /// 0030168 // platelet activation // traceable author statement /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // traceable author statement /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0031398 // positive regulation of protein ubiquitination // inferred from electronic annotation /// 0035437 // maintenance of protein localization in endoplasmic reticulum // inferred from mutant phenotype /// 0042149 // cellular response to glucose starvation // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from electronic annotation /// 0060904 // regulation of protein folding in endoplasmic reticulum // traceable author statement /// 0071236 // cellular response to antibiotic // inferred from electronic annotation /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation","0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from mutant phenotype /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0008180 // COP9 signalosome // inferred from direct assay /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0034663 // endoplasmic reticulum chaperone complex // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0000166 // nucleotide binding // inferred from electronic annotation /// 0001948 // glycoprotein binding // inferred from physical interaction /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from sequence or structural similarity /// 0019899 // enzyme binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0030674 // protein binding, bridging // non-traceable author statement /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0043022 // ribosome binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement /// 0051087 // chaperone binding // traceable author statement /// 0051787 // misfolded protein binding // inferred from direct assay","---","IPR004753 // Cell shape determining protein MreB/Mrl // 2.3E-20 /// IPR013126 // Heat shock protein 70 family // 3.2E-280"
"230158_at",-1.242319709,-1.868407674,-1.642981521,"DOWN","AA758751","chr7:89754209-89754914 (+) // 95.99 // q21.13 /// chr12:63952692-63953408 (-) // 99.03 // q14.2","dpy-19-like 2 (C. elegans)","DPY19L2","ENSG00000177990 /// ENSG00000235436 /// OTTHUMG00000158346 /// OTTHUMG00000168712","283417","613893 /// 613958","NP_776173 /// XP_006719411 /// XP_006719412 /// XP_006719413 /// XP_006719414 /// XP_006719415 /// XP_006719416 /// XP_006719417 /// XP_006719418 /// XP_006719419","NM_173812 /// XM_006719348 /// XM_006719349 /// XM_006719350 /// XM_006719351 /// XM_006719352 /// XM_006719353 /// XM_006719354 /// XM_006719355 /// XM_006719356 /// XR_429091 /// XR_429092","0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007286 // spermatid development // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation","0005634 // nucleus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation","---","IPR018732 // Dpy-19 // 3.8E-256"
"230252_at",2.73685776,2.767582552,3.194534716,"UP","AW183080","chr12:6728003-6728463 (-) // 25.54 // p13.31","lysophosphatidic acid receptor 5","LPAR5","ENSG00000184574 /// OTTHUMG00000168713","57121","606926","NP_001136433 /// NP_065133","NM_001142961 /// NM_020400","0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation","0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation","GPCRDB_Class_A_Rhodopsin-like // GenMAPP","IPR000276 // G protein-coupled receptor, rhodopsin-like // 5.0E-52"
"230318_at",1.363833124,1.063793583,1.727602421,"UP","T62088","chr14:94843084-94843548 (-) // 31.47 // q32.13","serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1","SERPINA1","ENSG00000197249 /// OTTHUMG00000150355","5265","107400 /// 606963 /// 613490","NP_000286 /// NP_001002235 /// NP_001002236 /// NP_001121172 /// NP_001121173 /// NP_001121174 /// NP_001121175 /// NP_001121176 /// NP_001121177 /// NP_001121178 /// NP_001121179","NM_000295 /// NM_001002235 /// NM_001002236 /// NM_001127700 /// NM_001127701 /// NM_001127702 /// NM_001127703 /// NM_001127704 /// NM_001127705 /// NM_001127706 /// NM_001127707","0001666 // response to hypoxia // inferred from electronic annotation /// 0002576 // platelet degranulation // traceable author statement /// 0006953 // acute-phase response // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007599 // hemostasis // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010288 // response to lead ion // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // not recorded /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030162 // regulation of proteolysis // not recorded /// 0030168 // platelet activation // traceable author statement /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0033986 // response to methanol // inferred from electronic annotation /// 0034014 // response to triglyceride // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0046687 // response to chromate // inferred from electronic annotation","0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // inferred from mutant phenotype /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0001948 // glycoprotein binding // inferred from physical interaction /// 0002020 // protease binding // inferred from physical interaction /// 0004866 // endopeptidase inhibitor activity // inferred from electronic annotation /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0004867 // serine-type endopeptidase inhibitor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030414 // peptidase inhibitor activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction","---","IPR023796 // Serpin domain // 4.7E-122"
"230425_at",-2.577864053,-1.547038705,-1.713469008,"DOWN","AI674183","chr3:134978852-134979305 (+) // 98.48 // q22.2","EPH receptor B1","EPHB1","ENSG00000154928 /// OTTHUMG00000159804","2047","600600","NP_004432","NM_004441","0001525 // angiogenesis // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0021545 // cranial nerve development // inferred from electronic annotation /// 0021631 // optic nerve morphogenesis // inferred from electronic annotation /// 0021952 // central nervous system projection neuron axonogenesis // inferred from sequence or structural similarity /// 0022008 // neurogenesis // inferred from sequence or structural similarity /// 0030010 // establishment of cell polarity // inferred from sequence or structural similarity /// 0031290 // retinal ganglion cell axon guidance // inferred from sequence or structural similarity /// 0031589 // cell-substrate adhesion // inferred from direct assay /// 0046328 // regulation of JNK cascade // inferred from direct assay /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048013 // ephrin receptor signaling pathway // inferred from direct assay /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0050965 // detection of temperature stimulus involved in sensory perception of pain // inferred from sequence or structural similarity /// 0051965 // positive regulation of synapse assembly // inferred from sequence or structural similarity /// 0060326 // cell chemotaxis // inferred from direct assay /// 0060996 // dendritic spine development // inferred from sequence or structural similarity /// 0060997 // dendritic spine morphogenesis // inferred from sequence or structural similarity /// 0061351 // neural precursor cell proliferation // inferred from sequence or structural similarity /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from direct assay","0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0005003 // ephrin receptor activity // inferred from electronic annotation /// 0005005 // transmembrane-ephrin receptor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008046 // axon guidance receptor activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation","---","IPR000719 // Protein kinase domain // 2.7E-52 /// IPR001090 // Ephrin receptor ligand binding domain // 8.1E-81 /// IPR001245 // Serine-threonine/tyrosine-protein kinase catalytic domain // 2.2E-100 /// IPR003961 // Fibronectin, type III // 6.0E-16 /// IPR003961 // Fibronectin, type III // 1.9E-18 /// IPR011510 // Sterile alpha motif, type 2 // 7.3E-22 /// IPR021129 // Sterile alpha motif, type 1 // 1.5E-24"
"230482_at",1.076885175,1.164197867,1.149223517,"UP","AF131837","chr1:77529659-77531396 (+) // 92.63 // p31.1","ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5","ST6GALNAC5","ENSG00000117069 /// OTTHUMG00000009687","81849","610134","NP_112227 /// XP_005271295","NM_030965 /// XM_005271238","0006486 // protein glycosylation // inferred from electronic annotation /// 0006688 // glycosphingolipid biosynthetic process // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0009312 // oligosaccharide biosynthetic process // inferred from sequence or structural similarity /// 0097503 // sialylation // inferred from electronic annotation /// 0097503 // sialylation // inferred from sequence or structural similarity","0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation","0001665 // alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity // inferred from sequence or structural similarity /// 0008373 // sialyltransferase activity // inferred from sequence or structural similarity /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation","---","IPR001675 // Glycosyl transferase, family 29 // 1.6E-43"
"230518_at",1.708589661,1.393991837,1.697742752,"UP","BF437750","chr11:118127629-118130838 (-) // 96.1 // q23.3","myelin protein zero-like 2","MPZL2","ENSG00000149573 /// OTTHUMG00000166967","10205","604873","NP_005788 /// NP_658911","NM_005797 /// NM_144765","0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation","0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0005515 // protein binding // inferred from physical interaction","---","IPR013106 // Immunoglobulin V-set domain // 1.3E-22"
"230526_at",1.5472199,1.69031478,2.447976807,"UP","BF515959","chr17:76103481-76104432 (-) // 97.93 // q25.3","TNRC6C antisense RNA 1","TNRC6C-AS1","ENSG00000204282 /// OTTHUMG00000177654","100131096","---","---","NR_040071","---","---","---","---","---"
"230536_at",-1.415653146,-2.039287692,-1.007184088,"DOWN","AJ300182","chr19:19672523-19729374 (-) // 94.64 // p13.11","pre-B-cell leukemia homeobox 4","PBX4","ENSG00000105717 /// OTTHUMG00000172310","80714","608127","NP_079521 /// XP_006722973 /// XP_006722974 /// XP_006722975","NM_025245 /// NR_038198 /// XM_006722910 /// XM_006722911 /// XM_006722912","0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred by curator /// 0045893 // positive regulation of transcription, DNA-templated // inferred by curator","0001741 // XY body // inferred from electronic annotation /// 0005634 // nucleus // inferred by curator","0003677 // DNA binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity","---","IPR001356 // Homeobox domain // 2.0E-21 /// IPR005542 // PBX // 4.0E-99 /// IPR005542 // PBX // 5.2E-45"
"230645_at",1.968525139,1.724670633,1.810489677,"UP","BF110588","chr9:85862311-85862785 (-) // 94.18 // q21.32","FERM domain containing 3","FRMD3","ENSG00000172159 /// OTTHUMG00000020103","257019","607619","NP_001231888 /// NP_001231889 /// NP_001231890 /// NP_001231891 /// NP_777598 /// XP_005251939","NM_001244959 /// NM_001244960 /// NM_001244961 /// NM_001244962 /// NM_174938 /// XM_005251882","---","0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation","0008092 // cytoskeletal protein binding // inferred from electronic annotation","---","IPR014847 // FERM adjacent (FA) // 1.2E-19 /// IPR018979 // FERM, N-terminal // 9.4E-25 /// IPR018980 // FERM, C-terminal PH-like domain // 3.7E-21 /// IPR019748 // FERM central domain // 4.5E-21"
"230673_at",-3.934902881,-3.230484949,-4.267815911,"DOWN","AV706971","chr8:110519979-110542559 (+) // 87.84 // q23.2","polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1","PKHD1L1","ENSG00000205038 /// OTTHUMG00000164934","93035","607843","NP_803875","NM_177531","0006955 // immune response // non-traceable author statement","0005615 // extracellular space // non-traceable author statement /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // non-traceable author statement","0004872 // receptor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation","---","IPR002909 // IPT domain // 9.9E-12 /// IPR002909 // IPT domain // 1.2E-20 /// IPR002909 // IPT domain // 4.0E-15 /// IPR002909 // IPT domain // 2.3E-13 /// IPR002909 // IPT domain // 1.0E-17 /// IPR002909 // IPT domain // 1.8E-15 /// IPR002909 // IPT domain // 1.0E-13 /// IPR002909 // IPT domain // 9.5E-15 /// IPR002909 // IPT domain // 5.3E-16 /// IPR002909 // IPT domain // 1.6E-12 /// IPR002909 // IPT domain // 2.6E-19 /// IPR002909 // IPT domain // 5.4E-15 /// IPR002909 // IPT domain // 3.3E-17 /// IPR002909 // IPT domain // 4.0E-18 /// IPR011658 // PA14 // 2.8E-12 /// IPR019316 // G8 domain // 5.5E-33 /// IPR019316 // G8 domain // 1.1E-32 /// IPR019316 // G8 domain // 2.0E-18"
"230776_at",-2.091171421,-1.133001087,-1.93288751,"DOWN","N59856","chr17:74150289-74150726 (+) // 95.62 // q25.1","RNF157 antisense RNA 1","RNF157-AS1","ENSG00000267128 /// OTTHUMG00000180136","100507218","---","---","NR_040017","---","---","---","---","---"
"230782_at",-2.179419521,-1.862383505,-1.149868847,"DOWN","AV699883","chr15:45367901-45369370 (+) // 46.36 // q21.1 /// chr15:45115614-45117083 (-) // 46.64 // q21.1","sorbitol dehydrogenase","SORD","ENSG00000140263 /// OTTHUMG00000131265","6652","182500","NP_003095","NM_003104 /// NR_034039","0006006 // glucose metabolic process // traceable author statement /// 0006060 // sorbitol metabolic process // inferred from electronic annotation /// 0006062 // sorbitol catabolic process // inferred from direct assay /// 0030317 // sperm motility // inferred from sequence or structural similarity /// 0030317 // sperm motility // non-traceable author statement /// 0046370 // fructose biosynthetic process // inferred from direct assay /// 0051160 // L-xylitol catabolic process // inferred from direct assay /// 0051164 // L-xylitol metabolic process // inferred from direct assay /// 0055114 // oxidation-reduction process // inferred from electronic annotation","0005615 // extracellular space // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0031514 // motile cilium // inferred from sequence or structural similarity /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0003939 // L-iditol 2-dehydrogenase activity // inferred from direct assay /// 0003939 // L-iditol 2-dehydrogenase activity // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0030246 // carbohydrate binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from direct assay","---","IPR013149 // Alcohol dehydrogenase, C-terminal // 2.5E-28 /// IPR013154 // Alcohol dehydrogenase GroES-like // 4.4E-27"
"230831_at",2.004171109,1.74596586,2.03763725,"UP","AW294986","chr15:44162961-44163540 (-) // 93.02 // q15.3","FERM domain containing 5","FRMD5","ENSG00000171877 /// OTTHUMG00000060475","84978","---","NP_001273419 /// NP_001273420 /// NP_116281 /// XP_005254786 /// XP_005254787","NM_001286490 /// NM_001286491 /// NM_032892 /// NR_104455 /// XM_005254729 /// XM_005254730","---","0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from electronic annotation","0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation","---","IPR014847 // FERM adjacent (FA) // 2.0E-19 /// IPR014847 // FERM adjacent (FA) // 1.8E-19 /// IPR018979 // FERM, N-terminal // 2.3E-25 /// IPR018979 // FERM, N-terminal // 2.0E-25 /// IPR018980 // FERM, C-terminal PH-like domain // 1.1E-17 /// IPR018980 // FERM, C-terminal PH-like domain // 9.4E-18 /// IPR019748 // FERM central domain // 8.0E-25 /// IPR019748 // FERM central domain // 6.8E-25"
"230836_at",1.717727874,1.060252809,1.162930245,"UP","AI422986","chr5:100142639-100143363 (-) // 98.5 // q21.1","ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4","ST8SIA4","ENSG00000113532 /// OTTHUMG00000128727","7903","602547","NP_005659 /// NP_778222 /// XP_005272135","NM_005668 /// NM_175052 /// XM_005272078","0001574 // ganglioside biosynthetic process // inferred from direct assay /// 0006464 // cellular protein modification process // traceable author statement /// 0006486 // protein glycosylation // inferred from direct assay /// 0006491 // N-glycan processing // inferred from direct assay /// 0007399 // nervous system development // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0009311 // oligosaccharide metabolic process // inferred from direct assay /// 0097503 // sialylation // inferred from direct assay /// 0097503 // sialylation // inferred from electronic annotation","0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030173 // integral component of Golgi membrane // inferred from electronic annotation","0003828 // alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity // inferred from direct assay /// 0008373 // sialyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0033691 // sialic acid binding // inferred by curator","---","IPR001675 // Glycosyl transferase, family 29 // 2.4E-78"
"230863_at",-1.556416488,-1.206981602,-2.037392531,"DOWN","R73030","chr2:169983618-169984061 (-) // 56.63 // q31.1","low density lipoprotein receptor-related protein 2","LRP2","ENSG00000081479 /// OTTHUMG00000132179","4036","222448 /// 600073","NP_004516 /// XP_006712589 /// XP_006712590 /// XP_006712591","NM_004525 /// XM_006712526 /// XM_006712527 /// XM_006712528","0001523 // retinoid metabolic process // traceable author statement /// 0006486 // protein glycosylation // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement /// 0006766 // vitamin metabolic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // inferred from sequence or structural similarity /// 0006897 // endocytosis // traceable author statement /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007603 // phototransduction, visible light // traceable author statement /// 0008202 // steroid metabolic process // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0042359 // vitamin D metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement","0005764 // lysosome // traceable author statement /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005903 // brush border // inferred from electronic annotation /// 0005903 // brush border // inferred from sequence or structural similarity /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031526 // brush border membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000033 // LDLR class B repeat // 9.0E-11 /// IPR000033 // LDLR class B repeat // 4.3E-9 /// IPR000033 // LDLR class B repeat // 4.8E-11 /// IPR000033 // LDLR class B repeat // 4.1E-15 /// IPR000033 // LDLR class B repeat // 2.8E-12 /// IPR000033 // LDLR class B repeat // 6.3E-14 /// IPR000033 // LDLR class B repeat // 4.7E-9 /// IPR000033 // LDLR class B repeat // 4.7E-10 /// IPR000033 // LDLR class B repeat // 2.7E-8 /// IPR000033 // LDLR class B repeat // 4.0E-18 /// IPR000033 // LDLR class B repeat // 1.1E-14 /// IPR000033 // LDLR class B repeat // 9.3E-11 /// IPR000033 // LDLR class B repeat // 2.6E-12 /// IPR000033 // LDLR class B repeat // 2.0E-13 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.6E-13 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 9.3E-14 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.1E-12 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 2.9E-14 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.2E-13 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 6.7E-10 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 8.1E-14 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.4E-15 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 5.4E-14 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.1E-15 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 2.5E-11 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 7.2E-12 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 4.7E-14 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 8.3E-9 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 3.2E-14 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 6.9E-15 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.2E-9 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.6E-10 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 6.0E-16 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 6.7E-14 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 3.3E-12 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 2.3E-13 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 5.3E-15 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 6.3E-14 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.2E-13 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 3.9E-9 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 2.6E-13 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 8.3E-17 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.6E-10 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 3.3E-15 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 7.7E-14 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.6E-13 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 5.8E-15 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 5.7E-12 /// IPR002172 // Low-density lipoprotein (LDL) receptor class A repeat // 1.4E-11"
"230964_at",-1.8424238,-1.439827511,-1.759180789,"DOWN","N66307","chr13:39459610-39460072 (+) // 97.26 // q13.3","FRAS1 related extracellular matrix protein 2","FREM2","ENSG00000150893 /// OTTHUMG00000016759","341640","219000 /// 608945","NP_997244","NM_207361","0002009 // morphogenesis of an epithelium // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation","0005604 // basement membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR003644 // Na-Ca exchanger/integrin-beta4 // 1.9E-18 /// IPR003644 // Na-Ca exchanger/integrin-beta4 // 1.8E-19 /// IPR003644 // Na-Ca exchanger/integrin-beta4 // 2.9E-17 /// IPR003644 // Na-Ca exchanger/integrin-beta4 // 3.2E-13 /// IPR003644 // Na-Ca exchanger/integrin-beta4 // 1.7E-21"
"231008_at",1.018208481,1.049297033,1.683302155,"UP","AI733001","chr6:40994629-40995200 (-) // 71.1 // p21.1","unc-5 homolog C (C. elegans)-like","UNC5CL","ENSG00000124602","222643","---","NP_775832","NM_173561","0006508 // proteolysis // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from direct assay","0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from direct assay","---","IPR000488 // Death domain // 4.0E-18 /// IPR000906 // ZU5 domain // 2.7E-30"
"231070_at",-2.014349594,-1.277883604,-2.234309062,"DOWN","BF431199","chr6:150725290-150725765 (+) // 95.77 // q25.1","iodotyrosine deiodinase","IYD","ENSG00000009765 /// OTTHUMG00000016347","389434","274800 /// 612025","NP_001158166 /// NP_001158167 /// NP_981932 /// XP_006715541 /// XP_006715542","NM_001164694 /// NM_001164695 /// NM_203395 /// XM_006715478 /// XM_006715479 /// XR_245516","0006590 // thyroid hormone generation // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation","0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0004447 // iodide peroxidase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // traceable author statement","---","IPR000415 // Nitroreductase-like // 8.0E-21 /// IPR000415 // Nitroreductase-like // 8.0E-27"
"231084_at",-1.273126892,-1.051789463,-2.012594848,"DOWN","AW665251","chr10:105889646-105891189 (-) // 97.36 // q25.1","WD repeat domain 96","WDR96","ENSG00000197748 /// OTTHUMG00000019002","80217","---","NP_079421 /// XP_005270228 /// XP_005270229 /// XP_005270230 /// XP_005270231 /// XP_005270232 /// XP_005270233","NM_025145 /// XM_005270171 /// XM_005270172 /// XM_005270173 /// XM_005270174 /// XM_005270175 /// XM_005270176","---","---","0005515 // protein binding // inferred from electronic annotation","---","---"
"231179_at",-2.241146621,-1.333519497,-2.301049473,"DOWN","R99291","chr6:33689440-33689889 (-) // 99.78 // p21.31","inositol hexakisphosphate kinase 3","IP6K3","ENSG00000161896 /// OTTHUMG00000014531","117283","606993","NP_001136355 /// NP_473452 /// XP_005248899 /// XP_005248900","NM_001142883 /// NM_054111 /// XM_005248842 /// XM_005248843","0006468 // protein phosphorylation // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032958 // inositol phosphate biosynthetic process // inferred from direct assay /// 0043647 // inositol phosphate metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046488 // phosphatidylinositol metabolic process // inferred from direct assay","0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement","0000166 // nucleotide binding // inferred from electronic annotation /// 0000831 // inositol hexakisphosphate 6-kinase activity // inferred from direct assay /// 0000832 // inositol hexakisphosphate 5-kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008440 // inositol-1,4,5-trisphosphate 3-kinase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0052723 // inositol hexakisphosphate 1-kinase activity // inferred from electronic annotation /// 0052724 // inositol hexakisphosphate 3-kinase activity // inferred from electronic annotation","PWY-6369 // MetaCyc","IPR005522 // Inositol polyphosphate kinase // 6.4E-67"
"231181_at",-4.068322291,-3.386124824,-4.758596792,"DOWN","AI683621","chr8:110544494-110544915 (+) // 97.0 // q23.2","---","---","---","---","---","---","---","---","---","---","---","---"
"231240_at",-2.370816477,-2.060326163,-1.515514787,"DOWN","AI038059","chr14:80664406-80665114 (+) // 97.66 // q31.1","deiodinase, iodothyronine, type II","DIO2","---","1734","601413","NP_000784 /// NP_001007024 /// NP_001229431 /// NP_001229432 /// NP_054644","NM_000793 /// NM_001007023 /// NM_001242502 /// NM_001242503 /// NM_013989","0001514 // selenocysteine incorporation // non-traceable author statement /// 0006590 // thyroid hormone generation // traceable author statement /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042403 // thyroid hormone metabolic process // inferred from direct assay /// 0042446 // hormone biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation","0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred by curator /// 0016021 // integral component of membrane // inferred from electronic annotation","0004800 // thyroxine 5'-deiodinase activity // inferred from direct assay /// 0004800 // thyroxine 5'-deiodinase activity // traceable author statement /// 0008430 // selenium binding // inferred by curator /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction","---","---"
"231311_at",1.301232933,1.572999796,1.412069712,"UP","AA725246","chr11:66449966-66450344 (-) // 18.11 // q13.2","---","---","---","---","---","---","---","---","---","---","---","---"
"231334_at",-2.110976346,-1.168054103,-1.09875636,"DOWN","AI697766","chr16:1763528-1764144 (-) // 66.75 // p13.3","uncharacterized LOC101929480","LOC101929480","ENSG00000261399 /// OTTHUMG00000176703","101929480","---","---","XR_243334 /// XR_248260 /// XR_253478","---","---","---","---","---"
"231358_at",-2.590525357,-2.107369755,-2.399831261,"DOWN","BE465760","chr18:48321490-48321964 (-) // 86.51 // q21.2","maestro","MRO","ENSG00000134042 /// OTTHUMG00000132692","83876","608080","NP_001120646 /// NP_001120647 /// NP_001120648 /// NP_114145 /// XP_005258422 /// XP_005258423 /// XP_005258424 /// XP_005258425","NM_001127174 /// NM_001127175 /// NM_001127176 /// NM_031939 /// XM_005258365 /// XM_005258366 /// XM_005258367 /// XM_005258368","---","0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation","0005488 // binding // inferred from electronic annotation","---","---"
"231513_at",3.459690832,2.279296117,2.326309416,"UP","BF111326","chr17:68175239-68175699 (-) // 96.84 // q24.3","---","---","---","---","---","---","---","---","---","---","---","---"
"231771_at",-2.58696564,-1.864283798,-1.613821104,"DOWN","AI694073","chr13:20796101-20797622 (-) // 98.64 // q12.11","gap junction protein, beta 6, 30kDa","GJB6","ENSG00000121742 /// OTTHUMG00000016515","10804","129500 /// 220290 /// 304400 /// 604418 /// 612643 /// 612645","NP_001103689 /// NP_001103690 /// NP_001103691 /// NP_006774","NM_001110219 /// NM_001110220 /// NM_001110221 /// NM_006783","0006915 // apoptotic process // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0042471 // ear morphogenesis // inferred from electronic annotation /// 0048839 // inner ear development // inferred from electronic annotation","0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005921 // gap junction // inferred from electronic annotation /// 0005922 // connexon complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay","0005515 // protein binding // inferred from electronic annotation","Calcium_regulation_in_cardiac_cells // GenMAPP","IPR013092 // Connexin, N-terminal // 5.5E-52 /// IPR019570 // Gap junction protein, cysteine-rich domain // 6.8E-33"
"231773_at",-1.954831677,-1.844135981,-2.223225874,"DOWN","BF002046","chr1:178819637-178834911 (-) // 96.87 // q25.2","angiopoietin-like 1","ANGPTL1","ENSG00000116194 /// OTTHUMG00000035075","9068","603874","NP_004664 /// XP_005245634","NM_004673 /// XM_005245577 /// XR_241102","0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation","0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005102 // receptor binding // inferred from electronic annotation","---","IPR002181 // Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain // 2.5E-78"
"231849_at",1.229715737,1.076751282,1.303534994,"UP","AL162069","chr12:52562782-52565500 (-) // 82.06 // q13.13","keratin 80","KRT80","ENSG00000167767 /// OTTHUMG00000150193","144501","611161","NP_001074961 /// NP_872313 /// XP_005268732 /// XP_005268733","NM_001081492 /// NM_182507 /// XM_005268675 /// XM_005268676","---","0005737 // cytoplasm // inferred from direct assay /// 0005882 // intermediate filament // inferred from direct assay /// 0030057 // desmosome // inferred from direct assay /// 0045095 // keratin filament // inferred from electronic annotation","0005198 // structural molecule activity // inferred from electronic annotation","---","IPR001664 // Intermediate filament protein // 5.2E-86 /// IPR001664 // Intermediate filament protein // 6.5E-86"
"231944_at",-1.688621076,-1.239276389,-1.142603668,"DOWN","AL045717","chr1:236378856-236381810 (-) // 99.83 // q42.3","ERO1-like beta (S. cerevisiae)","ERO1LB","ENSG00000086619 /// OTTHUMG00000039955","56605","615437","NP_063944","NM_019891","0006457 // protein folding // traceable author statement /// 0055114 // oxidation-reduction process // inferred from electronic annotation","0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation","0003756 // protein disulfide isomerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // non-traceable author statement /// 0016671 // oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor // inferred from electronic annotation /// 0050660 // flavin adenine dinucleotide binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // non-traceable author statement","---","IPR007266 // Endoplasmic reticulum oxidoreductin 1 // 2.4E-136"
"232056_at",3.43286688,2.713947369,2.579602098,"UP","AW470178","chr13:78109894-78219468 (+) // 96.45 // q22.3","sciellin","SCEL","ENSG00000136155 /// OTTHUMG00000017107","8796","604112","NP_001154178 /// NP_003834 /// NP_659001 /// XP_005266635 /// XP_006719945 /// XP_006719946 /// XP_006719947 /// XP_006719948 /// XP_006719949","NM_001160706 /// NM_003843 /// NM_144777 /// XM_005266578 /// XM_006719882 /// XM_006719883 /// XM_006719884 /// XM_006719885 /// XM_006719886","0008544 // epidermis development // inferred from sequence or structural similarity /// 0008544 // epidermis development // traceable author statement /// 0009790 // embryo development // inferred from sequence or structural similarity /// 0030216 // keratinocyte differentiation // inferred from direct assay","0001533 // cornified envelope // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","---"
"232067_at",2.22320079,1.958657568,1.561473651,"UP","BC004869","chr6:99728526-99797531 (-) // 93.8 // q16.2","failed axon connections homolog (Drosophila)","FAXC","ENSG00000146267 /// OTTHUMG00000015261","84553","---","NP_115900 /// XP_005267221 /// XP_006715644 /// XP_006715645","NM_032511 /// XM_005267164 /// XM_006715581 /// XM_006715582","---","0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","---","---","---"
"232231_at",2.960749231,2.540989574,2.258407863,"UP","AL353944","chr6:45515256-45518818 (+) // 70.84 // p21.1","runt-related transcription factor 2","RUNX2","ENSG00000124813 /// OTTHUMG00000014774","860","119600 /// 156510 /// 600211","NP_001015051 /// NP_001019801 /// NP_001265407 /// XP_006715294 /// XP_006715295 /// XP_006715296 /// XP_006715297","NM_001015051 /// NM_001024630 /// NM_001278478 /// NM_004348 /// NR_103532 /// NR_103533 /// XM_006715231 /// XM_006715232 /// XM_006715233 /// XM_006715234","0001501 // skeletal system development // inferred from electronic annotation /// 0001503 // ossification // traceable author statement /// 0001649 // osteoblast differentiation // inferred from expression pattern /// 0001649 // osteoblast differentiation // traceable author statement /// 0001958 // endochondral ossification // inferred from electronic annotation /// 0002051 // osteoblast fate commitment // inferred from electronic annotation /// 0002062 // chondrocyte differentiation // inferred from electronic annotation /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0002076 // osteoblast development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030278 // regulation of ossification // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from sequence or structural similarity /// 0032332 // positive regulation of chondrocyte differentiation // inferred from electronic annotation /// 0035115 // embryonic forelimb morphogenesis // inferred from electronic annotation /// 0040036 // regulation of fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0042475 // odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0042487 // regulation of odontogenesis of dentin-containing tooth // inferred from electronic annotation /// 0045667 // regulation of osteoblast differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from electronic annotation /// 0045879 // negative regulation of smoothened signaling pathway // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048469 // cell maturation // inferred from electronic annotation /// 0048701 // embryonic cranial skeleton morphogenesis // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0048863 // stem cell differentiation // inferred from electronic annotation /// 0071773 // cellular response to BMP stimulus // inferred from sequence or structural similarity /// 1901522 // positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus // inferred from sequence or structural similarity","0000790 // nuclear chromatin // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation","0000978 // RNA polymerase II core promoter proximal region sequence-specific DNA binding // inferred from electronic annotation /// 0001077 // RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // sequence-specific DNA binding transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0043425 // bHLH transcription factor binding // inferred from electronic annotation /// 0044212 // transcription regulatory region DNA binding // inferred from electronic annotation /// 0070491 // repressing transcription factor binding // inferred from electronic annotation","TGF_Beta_Signaling_Pathway // GenMAPP","IPR013524 // Runt domain // 5.8E-80 /// IPR013524 // Runt domain // 5.6E-80 /// IPR013524 // Runt domain // 5.1E-80 /// IPR013711 // Runx, C-terminal  domain // 1.6E-47 /// IPR013711 // Runx, C-terminal  domain // 1.5E-47 /// IPR013711 // Runx, C-terminal  domain // 1.4E-47"
"232304_at",2.203383964,1.91362135,1.04285569,"UP","AK026714","chr2:64331834-64333714 (-) // 86.92 // p14","Homo sapiens cDNA: FLJ23061 fis, clone LNG04647. /// pellino E3 ubiquitin protein ligase 1","AK026714 /// PELI1","---","57162","614797","NP_065702 /// XP_005264493 /// XP_005264494","NM_020651 /// XM_005264436 /// XM_005264437","0000209 // protein polyubiquitination // inferred from electronic annotation /// 0001819 // positive regulation of cytokine production // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0008063 // Toll signaling pathway // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0030890 // positive regulation of B cell proliferation // inferred from electronic annotation /// 0031398 // positive regulation of protein ubiquitination // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034141 // positive regulation of toll-like receptor 3 signaling pathway // inferred from electronic annotation /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034145 // positive regulation of toll-like receptor 4 signaling pathway // inferred from electronic annotation /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042130 // negative regulation of T cell proliferation // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // traceable author statement /// 0043331 // response to dsRNA // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0050868 // negative regulation of T cell activation // inferred from electronic annotation /// 0050871 // positive regulation of B cell activation // inferred from electronic annotation /// 0070936 // protein K48-linked ubiquitination // inferred from electronic annotation","0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement","0004842 // ubiquitin-protein transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation","---","---"
"232404_at",1.166862191,1.027577593,1.311851755,"UP","AB033028","chrX:50334646-50557044 (-) // 89.44 // p11.22","shroom family member 4","SHROOM4","ENSG00000158352 /// OTTHUMG00000021521","57477","300434 /// 300579","NP_065768 /// XP_006724653 /// XP_006724654","NM_020717 /// NR_027121 /// XM_006724590 /// XM_006724591","0000902 // cell morphogenesis // inferred from direct assay /// 0007015 // actin filament organization // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007420 // brain development // inferred from direct assay /// 0030036 // actin cytoskeleton organization // non-traceable author statement /// 0050890 // cognition // inferred from direct assay","0001725 // stress fiber // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0009898 // cytoplasmic side of plasma membrane // inferred from direct assay /// 0009925 // basal plasma membrane // inferred from sequence or structural similarity /// 0015629 // actin cytoskeleton // inferred from sequence or structural similarity /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0016460 // myosin II complex // inferred from sequence or structural similarity /// 0030864 // cortical actin cytoskeleton // inferred from sequence or structural similarity /// 0031941 // filamentous actin // inferred from direct assay","0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from sequence or structural similarity","---","IPR001478 // PDZ domain // 2.7E-9 /// IPR014799 // Apx/shroom, ASD2 // 4.3E-103"
"232424_at",-2.287253144,-1.637911662,-1.255202389,"DOWN","AI623202","chr1:3328263-3355183 (+) // 98.09 // p36.32","PR domain containing 16","PRDM16","ENSG00000142611 /// OTTHUMG00000000581","63976","605557 /// 615373","NP_071397 /// NP_955533 /// XP_005244829 /// XP_005244830 /// XP_005244831 /// XP_006710877","NM_022114 /// NM_199454 /// XM_005244772 /// XM_005244773 /// XM_005244774 /// XM_006710814","0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0022008 // neurogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0030853 // negative regulation of granulocyte differentiation // inferred from direct assay /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0043457 // regulation of cellular respiration // inferred from sequence or structural similarity /// 0043586 // tongue development // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0050872 // white fat cell differentiation // inferred from electronic annotation /// 0050873 // brown fat cell differentiation // inferred from sequence or structural similarity /// 0060021 // palate development // inferred from electronic annotation","0005634 // nucleus // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from sequence or structural similarity","0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046332 // SMAD binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR003656 // Zinc finger, BED-type // 2.1E-8 /// IPR007087 // Zinc finger, C2H2 // 2.2E-8 /// IPR007087 // Zinc finger, C2H2 // 5.5E-9 /// IPR007087 // Zinc finger, C2H2 // 7.0E-11 /// IPR007087 // Zinc finger, C2H2 // 6.9E-9"
"232617_at",1.448599032,1.188396995,1.134792706,"UP","AK024855","chr1:150703020-150705436 (-) // 36.63 // q21.3","cathepsin S","CTSS","ENSG00000163131 /// OTTHUMG00000035010","1520","116845","NP_001186668 /// NP_004070","NM_001199739 /// NM_004079","0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002250 // adaptive immune response // inferred from expression pattern /// 0002474 // antigen processing and presentation of peptide antigen via MHC class I // traceable author statement /// 0002480 // antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent // traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0006955 // immune response // traceable author statement /// 0019882 // antigen processing and presentation // traceable author statement /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030574 // collagen catabolic process // inferred from direct assay /// 0034769 // basement membrane disassembly // inferred from direct assay /// 0042590 // antigen processing and presentation of exogenous peptide antigen via MHC class I // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0051603 // proteolysis involved in cellular protein catabolic process // inferred from direct assay /// 0097067 // cellular response to thyroid hormone stimulus // inferred from expression pattern","0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0036021 // endolysosome lumen // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay","0001968 // fibronectin binding // inferred from physical interaction /// 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0005518 // collagen binding // inferred from direct assay /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0043236 // laminin binding // inferred from direct assay /// 0043394 // proteoglycan binding // inferred from physical interaction","---","IPR000668 // Peptidase C1A, papain C-terminal // 8.9E-87 /// IPR013201 // Proteinase inhibitor I29, cathepsin propeptide // 2.5E-17"
"233111_at",-1.333899854,-1.165007672,-1.844281739,"DOWN","AU159390","chr8:134067203-134070019 (+) // 67.06 // q24.22","papillary thyroid carcinoma susceptibility candidate 1 (non-protein coding)","PTCSC1","---","100302522","---","---","---","---","---","---","---","---"
"233338_at",1.678943093,2.364054112,1.395214887,"UP","AU145865","chr22:18743860-18745414 (+) // 65.73 // q11.21 /// chr22:21544891-21546445 (+) // 85.39 // q11.21 /// chr22:20348903-20350457 (+) // 66.43 // q11.21 /// chr22:20632124-20633678 (-) // 65.86 // q11.21 /// chr22:18852559-18854113 (-) // 65.92 // q11.21 /// chr22:21655278-21656832 (-) // 65.73 // q11.21 /// chr22:18660797-18662355 (-) // 65.53 // q11.21","family with sequence similarity 230, member B (non-protein coding) /// family with sequence similarity 230, member C /// uncharacterized LOC729461","FAM230B /// FAM230C /// LOC729461","ENSG00000187979 /// ENSG00000206142 /// ENSG00000215498 /// OTTHUMG00000150103 /// OTTHUMG00000150782 /// OTTHUMG00000150795","26080 /// 642633 /// 729461","---","XP_003403538 /// XP_006726884 /// XP_006726885 /// XP_006726886 /// XP_006726887 /// XP_006726888","NM_201401 /// NM_201565 /// NR_027278 /// NR_108107 /// XM_003403490 /// XM_006726821 /// XM_006726822 /// XM_006726823 /// XM_006726824 /// XM_006726825 /// XR_433733","---","---","---","---","---"
"233720_at",-1.304376192,-1.637975431,-1.15094015,"DOWN","AK000782","chr4:186557820-186560218 (-) // 67.12 // q35.1","sorbin and SH3 domain containing 2","SORBS2","---","8470","---","NP_001139142 /// NP_001139143 /// NP_001139144 /// NP_001139145 /// NP_001139146 /// NP_001139147 /// NP_001257700 /// NP_003594 /// NP_066547 /// XP_005263359 /// XP_005263362 /// XP_005263363 /// XP_005263364 /// XP_005263365 /// XP_005263367 /// XP_005263368 /// XP_005263369 /// XP_005263370 /// XP_006714408 /// XP_006714409 /// XP_006714410 /// XP_006714411 /// XP_006714412 /// XP_006714413 /// XP_006714414 /// XP_006714415 /// XP_006714416 /// XP_006714417 /// XP_006714418 /// XP_006714419 /// XP_006714420 /// XP_006714421 /// XP_006714422 /// XP_006714423 /// XP_006714424 /// XP_006714425 /// XP_006714426 /// XP_006714427 /// XP_006714428 /// XP_006714429 /// XP_006714430 /// XP_006714431 /// XP_006714432 /// XP_006714433 /// XP_006714434 /// XP_006714435 /// XP_006714436 /// XP_006714437 /// XP_006714438 /// XP_006714439 /// XP_006714440 /// XP_006714441 /// XP_006714442 /// XP_006714443 /// XP_006714444 /// XP_006714445 /// XP_006714446 /// XP_006714447 /// XP_006714448 /// XP_006714449 /// XP_006714450 /// XP_006714451 /// XP_006714452 /// XP_006714453","NM_001145670 /// NM_001145671 /// NM_001145672 /// NM_001145673 /// NM_001145674 /// NM_001145675 /// NM_001270771 /// NM_003603 /// NM_021069 /// XM_005263302 /// XM_005263305 /// XM_005263306 /// XM_005263307 /// XM_005263308 /// XM_005263310 /// XM_005263311 /// XM_005263312 /// XM_005263313 /// XM_006714345 /// XM_006714346 /// XM_006714347 /// XM_006714348 /// XM_006714349 /// XM_006714350 /// XM_006714351 /// XM_006714352 /// XM_006714353 /// XM_006714354 /// XM_006714355 /// XM_006714356 /// XM_006714357 /// XM_006714358 /// XM_006714359 /// XM_006714360 /// XM_006714361 /// XM_006714362 /// XM_006714363 /// XM_006714364 /// XM_006714365 /// XM_006714366 /// XM_006714367 /// XM_006714368 /// XM_006714369 /// XM_006714370 /// XM_006714371 /// XM_006714372 /// XM_006714373 /// XM_006714374 /// XM_006714375 /// XM_006714376 /// XM_006714377 /// XM_006714378 /// XM_006714379 /// XM_006714380 /// XM_006714381 /// XM_006714382 /// XM_006714383 /// XM_006714384 /// XM_006714385 /// XM_006714386 /// XM_006714387 /// XM_006714388 /// XM_006714389 /// XM_006714390","0007015 // actin filament organization // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation","0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030018 // Z disc // non-traceable author statement /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation","0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008093 // cytoskeletal adaptor activity // traceable author statement /// 0008307 // structural constituent of muscle // traceable author statement /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation","---","---"
"235085_at",-1.413584756,-1.035323007,-1.279511802,"DOWN","BF739767","chr8:8175257-8176263 (-) // 94.83 // p23.1","homolog of rat pragma of Rnd2","SGK223","OTTHUMG00000163709","157285","---","NP_001074295 /// XP_005272426 /// XP_005272427","NM_001080826 /// XM_005272369 /// XM_005272370","0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation","---","0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation","---","IPR000719 // Protein kinase domain // 9.8E-15 /// IPR001245 // Serine-threonine/tyrosine-protein kinase catalytic domain // 6.4E-9"
"235102_x_at",-2.035071055,-2.429470113,-1.818974284,"DOWN","AI684439","chr17:18966936-18967449 (-) // 52.78 // p11.2","small nucleolar RNA, C/D box 3A /// small nucleolar RNA, C/D box 3B-1 /// small nucleolar RNA, C/D box 3B-2 /// small nucleolar RNA, C/D box 3C /// small nucleolar RNA, C/D box 3D","SNORD3A /// SNORD3B-1 /// SNORD3B-2 /// SNORD3C /// SNORD3D","ENSG00000262074 /// ENSG00000262202 /// ENSG00000263934 /// ENSG00000264940 /// ENSG00000265185 /// OTTHUMG00000178152 /// OTTHUMG00000178158 /// OTTHUMG00000178445 /// OTTHUMG00000178446 /// OTTHUMG00000178499","26851 /// 780851 /// 780852 /// 780853 /// 780854","180710","---","NR_002906 /// NR_003271 /// NR_003924 /// NR_006880 /// NR_006881 /// NR_006882","---","---","---","---","---"
"235182_at",-1.213395269,-1.061983717,-1.612169495,"DOWN","AI816793","chr20:13280345-13281298 (+) // 98.45 // p12.1","isthmin 1, angiogenesis inhibitor","ISM1","ENSG00000101230 /// OTTHUMG00000031902","140862","615793","NP_543016","NM_080826","---","0005576 // extracellular region // inferred from electronic annotation","---","---","IPR000884 // Thrombospondin, type 1 repeat // 2.1E-10 /// IPR005533 // AMOP // 1.5E-44"
"235201_at",-2.390021172,-1.819165031,-1.142574696,"DOWN","AW167727","chr7:114331396-114331987 (+) // 99.49 // q31.1","forkhead box P2","FOXP2","ENSG00000128573 /// OTTHUMG00000023131","93986","602081 /// 605317","NP_001166237 /// NP_001166238 /// NP_055306 /// NP_683696 /// NP_683697 /// NP_683698 /// XP_006716242 /// XP_006716243","NM_001172766 /// NM_001172767 /// NM_014491 /// NM_148898 /// NM_148899 /// NM_148900 /// NR_033766 /// NR_033767 /// XM_006716179 /// XM_006716180 /// XR_428189","0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // not recorded /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007389 // pattern specification process // not recorded /// 0007519 // skeletal muscle tissue development // not recorded /// 0009790 // embryo development // inferred from electronic annotation /// 0009791 // post-embryonic development // not recorded /// 0021549 // cerebellum development // not recorded /// 0021757 // caudate nucleus development // inferred from mutant phenotype /// 0021758 // putamen development // inferred from mutant phenotype /// 0021987 // cerebral cortex development // inferred from expression pattern /// 0030324 // lung development // inferred from electronic annotation /// 0040007 // growth // not recorded /// 0042297 // vocal learning // not recorded /// 0043010 // camera-type eye development // not recorded /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048286 // lung alveolus development // not recorded /// 0048745 // smooth muscle tissue development // not recorded /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0060013 // righting reflex // not recorded /// 0060501 // positive regulation of epithelial cell proliferation involved in lung morphogenesis // not recorded","0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded","0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008301 // DNA binding, bending // not recorded /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // not recorded","---","IPR001766 // Transcription factor, fork head // 2.0E-29 /// IPR001766 // Transcription factor, fork head // 2.0E-29 /// IPR001766 // Transcription factor, fork head // 4.3E-24"
"235228_at",-2.000171045,-1.47938916,-1.366647792,"DOWN","AI376433","chr2:56611908-56613307 (+) // 99.01 // p16.1","coiled-coil domain containing 85A","CCDC85A","ENSG00000055813 /// ENSG00000271894 /// OTTHUMG00000152033 /// OTTHUMG00000185573","114800","---","NP_001073902 /// XP_005264182","NM_001080433 /// XM_005264125","---","---","---","---","IPR019359 // Protein of unknown function DUF2216, coiled-coil // 7.1E-104"
"235251_at",-1.032283815,-1.576710385,-1.762418118,"DOWN","AW292765","chr3:44163003-44163856 (+) // 55.23 // p21.32","Homo sapiens cDNA FLJ42786 fis, clone BRAWH3006761. /// ---","DQ592230 /// RP4-555D20.2","ENSG00000261786 /// OTTHUMG00000175704","---","---","---","---","---","---","---","---","---"
"235438_at",-1.421980047,-1.18966082,-1.36640855,"DOWN","AW162011","chr8:65503409-65504470 (-) // 97.86 // q12.3","---","---","---","---","---","---","---","---","---","---","---","---"
"235561_at",-2.101254817,-1.179648921,-1.229386836,"DOWN","T16544","chr18:54264396-54264879 (-) // 85.34 // q21.31","thioredoxin-like 1","TXNL1","ENSG00000091164 /// OTTHUMG00000132722","9352","603049","NP_004777 /// XP_006722643 /// XP_006722644","NM_004786 /// NR_024546 /// XM_006722580 /// XM_006722581 /// XR_430086","0006662 // glycerol ether metabolic process // inferred from electronic annotation /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation","0000502 // proteasome complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0015036 // disulfide oxidoreductase activity // inferred from direct assay","---","IPR010400 // PITH domain // 3.4E-41 /// IPR013766 // Thioredoxin domain // 3.6E-21"
"235629_at",3.166103085,3.834363079,3.387018387,"UP","AI333596","chr2:216230712-216231731 (-) // 84.32 // q35","---","---","---","---","---","---","---","---","---","---","---","---"
"235746_s_at",-3.140019831,-2.561355663,-3.370233108,"DOWN","BE048919","chr2:160788361-160798419 (-) // 76.94 // q24.2","phospholipase A2 receptor 1, 180kDa","PLA2R1","ENSG00000153246 /// OTTHUMG00000154087","22925","604939","NP_001007268 /// NP_001182570 /// NP_031392 /// XP_005246449 /// XP_005246450 /// XP_005246452 /// XP_006712432","NM_001007267 /// NM_001195641 /// NM_007366 /// XM_005246392 /// XM_005246393 /// XM_005246395 /// XM_006712369","0001816 // cytokine production // inferred from mutant phenotype /// 0006897 // endocytosis // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from direct assay /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0043517 // positive regulation of DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype /// 0072593 // reactive oxygen species metabolic process // inferred from direct assay /// 0090238 // positive regulation of arachidonic acid secretion // inferred from sequence or structural similarity /// 0090399 // replicative senescence // inferred from mutant phenotype /// 0090403 // oxidative stress-induced premature senescence // inferred from mutant phenotype /// 1900138 // negative regulation of phospholipase A2 activity // inferred from sequence or structural similarity /// 1900139 // negative regulation of arachidonic acid secretion // inferred from sequence or structural similarity","0005576 // extracellular region // inferred from sequence or structural similarity /// 0005576 // extracellular region // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0004872 // receptor activity // inferred from direct assay /// 0030246 // carbohydrate binding // inferred from electronic annotation /// 0043274 // phospholipase binding // inferred from electronic annotation /// 0043274 // phospholipase binding // inferred from physical interaction","---","---"
"235759_at",-1.912185517,-1.969794671,-1.858877154,"DOWN","AI095542","chr8:91968979-91969849 (-) // 84.87 // q21.3","---","---","---","---","---","---","---","---","---","---","---","---"
"235766_x_at",1.211665616,1.480921363,1.457587286,"UP","AA743462","chr15:55495166-55495613 (-) // 97.16 // q21.3","RAB27A, member RAS oncogene family","RAB27A","ENSG00000069974 /// OTTHUMG00000131959","5873","603868 /// 607624","NP_004571 /// NP_899057 /// NP_899058 /// NP_899059 /// XP_005254633 /// XP_005254634","NM_004580 /// NM_183234 /// NM_183235 /// NM_183236 /// XM_005254576 /// XM_005254577","0006184 // GTP catabolic process // inferred from electronic annotation /// 0006605 // protein targeting // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from mutant phenotype /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0032400 // melanosome localization // inferred from electronic annotation /// 0032402 // melanosome transport // inferred from electronic annotation /// 0043316 // cytotoxic T cell degranulation // inferred from electronic annotation /// 0043320 // natural killer cell degranulation // inferred from electronic annotation /// 0043473 // pigmentation // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045921 // positive regulation of exocytosis // inferred from mutant phenotype /// 0051875 // pigment granule localization // inferred from electronic annotation /// 0051904 // pigment granule transport // inferred from electronic annotation /// 0071985 // multivesicular body sorting pathway // inferred from mutant phenotype","0001750 // photoreceptor outer segment // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0030425 // dendrite // inferred from direct assay /// 0030667 // secretory granule membrane // inferred from electronic annotation /// 0032585 // multivesicular body membrane // inferred from direct assay /// 0042470 // melanosome // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070382 // exocytic vesicle // inferred from direct assay","0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from direct assay /// 0005525 // GTP binding // inferred from sequence or structural similarity /// 0019003 // GDP binding // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0031489 // myosin V binding // inferred from electronic annotation","---","IPR000795 // Elongation factor, GTP-binding domain // 2.4E-9 /// IPR001806 // Small GTPase superfamily // 8.3E-60 /// IPR006689 // Small GTPase superfamily, ARF/SAR type // 7.1E-15 /// IPR013684 // Mitochondrial Rho-like // 9.8E-20"
"235801_at",2.168720317,1.010327562,1.567424585,"UP","AI760262","chr8:15623040-15623494 (+) // 64.58 // p22","tumor suppressor candidate 3","TUSC3","ENSG00000104723 /// OTTHUMG00000094803","7991","601385 /// 611093","NP_006756 /// NP_839952 /// XP_005273703 /// XP_005273704 /// XP_005273705","NM_006765 /// NM_178234 /// XM_005273646 /// XM_005273647 /// XM_005273648","0006487 // protein N-linked glycosylation // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015693 // magnesium ion transport // inferred from genetic interaction /// 0015693 // magnesium ion transport // inferred from mutant phenotype /// 0018279 // protein N-linked glycosylation via asparagine // inferred from sequence or structural similarity /// 0018279 // protein N-linked glycosylation via asparagine // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0050890 // cognition // inferred from mutant phenotype","0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0008250 // oligosaccharyltransferase complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0004579 // dolichyl-diphosphooligosaccharide-protein glycotransferase activity // inferred from sequence or structural similarity /// 0015095 // magnesium ion transmembrane transporter activity // inferred from mutant phenotype","---","IPR013766 // Thioredoxin domain // 9.3E-9 /// IPR021149 // Oligosaccharyl transferase complex, subunit OST3/OST6 // 4.3E-57"
"235867_at",-1.8843048,-1.060490017,-1.533415563,"DOWN","AI459140","---","glutathione S-transferase mu 3 (brain)","GSTM3","ENSG00000134202","2947","138390","NP_000840","NM_000849 /// NR_024537","0006749 // glutathione metabolic process // inferred from direct assay /// 0006805 // xenobiotic metabolic process // traceable author statement /// 0008065 // establishment of blood-nerve barrier // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0018916 // nitrobenzene metabolic process // inferred from direct assay /// 0042178 // xenobiotic catabolic process // inferred from direct assay /// 0043627 // response to estrogen // inferred from expression pattern /// 0044281 // small molecule metabolic process // traceable author statement /// 0070458 // cellular detoxification of nitrogen compound // inferred from direct assay /// 1901687 // glutathione derivative biosynthetic process // traceable author statement","0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0004364 // glutathione transferase activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0043295 // glutathione binding // inferred from direct assay","Circadian_Exercise // GenMAPP /// PWY-4061 // HumanCyc","IPR004045 // Glutathione S-transferase, N-terminal // 1.1E-24 /// IPR004046 // Glutathione S-transferase, C-terminal // 2.3E-21"
"236038_at",-2.222658897,-1.755500785,-2.12456834,"DOWN","N50714","chr4:141780961-141781407 (-) // 98.45 // q31.21","ring finger protein 150","RNF150","ENSG00000170153 /// OTTHUMG00000161380","57484","---","NP_065775 /// XP_005263207","NM_020724 /// XM_005263150","---","0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR003137 // Protease-associated domain, PA // 2.2E-11 /// IPR018957 // Zinc finger, C3HC4 RING-type // 1.9E-11"
"236065_at",3.177822379,2.061696544,1.467668652,"UP","BF431214","chr12:40616879-40617324 (-) // 51.3 // q12","---","---","---","---","---","---","---","---","---","---","---","---"
"236277_at",-1.112305378,-2.278961706,-2.123021418,"DOWN","H23551","chrX:110371892-110372427 (+) // 82.31 // q23","Homo sapiens primary neuroblastoma cDNA, clone:Nbla04246, full insert sequence.","AF070581","---","---","---","---","---","---","---","---","---","---"
"236313_at",2.408180713,1.435712694,2.988378311,"UP","AW444761","chr9:22002898-22003475 (-) // 94.51 // p21.3","cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)","CDKN2B","ENSG00000147883 /// OTTHUMG00000019691","1030","600431","NP_004927 /// NP_511042","NM_004936 /// NM_078487","0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0000086 // G2/M transition of mitotic cell cycle // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0001889 // liver development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from mutant phenotype /// 0007093 // mitotic cell cycle checkpoint // inferred from mutant phenotype /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0010467 // gene expression // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0030219 // megakaryocyte differentiation // inferred from expression pattern /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from mutant phenotype /// 0030858 // positive regulation of epithelial cell differentiation // inferred from electronic annotation /// 0031668 // cellular response to extracellular stimulus // inferred from mutant phenotype /// 0031670 // cellular response to nutrient // inferred from mutant phenotype /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042326 // negative regulation of phosphorylation // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0048536 // spleen development // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from mutant phenotype /// 0071901 // negative regulation of protein serine/threonine kinase activity // inferred from direct assay /// 0071901 // negative regulation of protein serine/threonine kinase activity // non-traceable author statement /// 2000134 // negative regulation of G1/S transition of mitotic cell cycle // inferred from electronic annotation","0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement","0004861 // cyclin-dependent protein serine/threonine kinase inhibitor activity // inferred from direct assay /// 0004861 // cyclin-dependent protein serine/threonine kinase inhibitor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction","G1_to_S_cell_cycle_Reactome // GenMAPP","---"
"236451_at",-1.590879154,-1.16149666,-1.142578283,"DOWN","AA825510","chr2:162104788-162105560 (+) // 94.66 // q24.2","uncharacterized LOC100996579","LOC100996579","ENSG00000227403 /// OTTHUMG00000151885","100996579","---","---","NR_110163 /// NR_110164","---","---","---","---","---"
"236640_at",1.599533548,1.272051746,1.528410205,"UP","AI638169","chr11:121899034-121899389 (-) // 83.91 // q24.1","uncharacterized LOC100507165","LOC100507165","ENSG00000255248 /// OTTHUMG00000166058","100507165","---","---","XR_110530 /// XR_171923","---","---","---","---","---"
"236783_at",-2.115564395,-1.122311314,-1.481139613,"DOWN","AI732844","chr4:20730228-20731219 (-) // 92.17 // p15.31","Kv channel interacting protein 4","KCNIP4","ENSG00000185774 /// OTTHUMG00000128557","80333","608182","NP_001030175 /// NP_001030176 /// NP_079497 /// NP_671710 /// NP_671711 /// NP_671712 /// XP_005248247","NM_001035003 /// NM_001035004 /// NM_025221 /// NM_147181 /// NM_147182 /// NM_147183 /// XM_005248190","0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0034765 // regulation of ion transmembrane transport // inferred from electronic annotation /// 0071805 // potassium ion transmembrane transport // inferred from electronic annotation","0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation","0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005267 // potassium channel activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR002048 // EF-hand domain // 5.2E-12 /// IPR002048 // EF-hand domain // 4.0E-12 /// IPR019577 // SPARC/Testican, calcium-binding domain // 2.5E-9 /// IPR019577 // SPARC/Testican, calcium-binding domain // 1.8E-9"
"237400_at",-1.072246792,-1.086350076,-1.082819009,"DOWN","AI308101","chr14:50793060-50793482 (-) // 94.76 // q21.3","---","RP11-247L20.4","ENSG00000259071 /// OTTHUMG00000170886","---","---","---","---","---","---","---","---","---"
"238047_at",3.567404328,3.348001753,2.835511294,"UP","AA405456","chrX:130223249-130223857 (+) // 96.49 // q26.1","Rho GTPase activating protein 36","ARHGAP36","ENSG00000147256 /// OTTHUMG00000022402","158763","---","NP_001269536 /// NP_659404 /// XP_006724792","NM_001282607 /// NM_144967 /// XM_006724729","0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement","0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement","0005096 // GTPase activator activity // inferred from electronic annotation","---","IPR000198 // Rho GTPase-activating protein domain // 7.5E-43 /// IPR000198 // Rho GTPase-activating protein domain // 7.1E-43 /// IPR000198 // Rho GTPase-activating protein domain // 6.7E-43 /// IPR000198 // Rho GTPase-activating protein domain // 4.2E-43"
"238116_at",-1.803982016,-1.228660031,-1.080322451,"DOWN","AW959427","chr16:80574853-80584541 (+) // 81.44 // q23.2","dynein, light chain, roadblock-type 2","DYNLRB2","ENSG00000168589 /// OTTHUMG00000137622","83657","607168","NP_570967 /// XP_005256245 /// XP_006721358 /// XP_006721359","NM_130897 /// XM_005256188 /// XM_006721295 /// XM_006721296","0006810 // transport // inferred from electronic annotation /// 0007018 // microtubule-based movement // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement","0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005868 // cytoplasmic dynein complex // inferred from sequence or structural similarity /// 0005868 // cytoplasmic dynein complex // non-traceable author statement /// 0005874 // microtubule // inferred from electronic annotation /// 0030286 // dynein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0003774 // motor activity // inferred from electronic annotation /// 0003777 // microtubule motor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation","---","IPR004942 // Dynein light chain-related // 8.8E-33 /// IPR004942 // Dynein light chain-related // 3.5E-33 /// IPR004942 // Dynein light chain-related // 4.0E-10"
"238178_at",-1.011835755,-1.220875277,-1.1933726,"DOWN","BF110268","chr1:56956665-56957120 (-) // 35.56 // p32.2","---","---","---","---","---","---","---","---","---","---","---","---"
"238692_at",-1.896655083,-1.800571399,-1.358550805,"DOWN","AL040935","chr12:108035875-108052530 (+) // 90.33 // q23.3","BTB (POZ) domain containing 11","BTBD11","ENSG00000151136 /// OTTHUMG00000150413","121551","---","NP_001017523 /// NP_001018082 /// XP_005268702","NM_001017523 /// NM_001018072 /// NM_152322 /// XM_005268645","---","0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0005515 // protein binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation","---","IPR002110 // Ankyrin repeat // 5.0E-13 /// IPR002110 // Ankyrin repeat // 3.2E-8 /// IPR002110 // Ankyrin repeat // 3.0E-9 /// IPR002110 // Ankyrin repeat // 2.6E-13 /// IPR002110 // Ankyrin repeat // 1.7E-8 /// IPR002110 // Ankyrin repeat // 1.6E-9 /// IPR013069 // BTB/POZ // 8.7E-24 /// IPR013069 // BTB/POZ // 4.0E-24"
"238727_at",-2.557044224,-1.611517314,-1.367832291,"DOWN","AA031832","chr2:223181851-223183070 (-) // 95.24 // q36.1","uncharacterized LOC440934","LOC440934","ENSG00000267034 /// OTTHUMG00000180633","440934","---","---","XR_108436 /// XR_171351","---","---","---","---","---"
"238784_at",-1.036003468,-1.855697733,-1.872013338,"DOWN","AI039361","chr12:63953964-63963131 (-) // 93.22 // q14.2","dpy-19-like 2 (C. elegans)","DPY19L2","ENSG00000177990 /// OTTHUMG00000168712","283417","613893 /// 613958","NP_776173 /// XP_006719411 /// XP_006719412 /// XP_006719413 /// XP_006719414 /// XP_006719415 /// XP_006719416 /// XP_006719417 /// XP_006719418 /// XP_006719419","NM_173812 /// XM_006719348 /// XM_006719349 /// XM_006719350 /// XM_006719351 /// XM_006719352 /// XM_006719353 /// XM_006719354 /// XM_006719355 /// XM_006719356 /// XR_429091 /// XR_429092","0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007286 // spermatid development // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation","0005634 // nucleus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation","---","IPR018732 // Dpy-19 // 3.8E-256 /// IPR018732 // Dpy-19 // 1.2E-89"
"238835_at",-2.632245595,-2.992861947,-2.401162026,"DOWN","AV707318","chr12:63536907-63537467 (-) // 94.11 // q14.2","arginine vasopressin receptor 1A","AVPR1A","ENSG00000166148 /// OTTHUMG00000169980","552","600821","NP_000697 /// XP_005269059","NM_000706 /// XM_005269002","0001992 // regulation of systemic arterial blood pressure by vasopressin // inferred from electronic annotation /// 0002125 // maternal aggressive behavior // inferred from electronic annotation /// 0003084 // positive regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007621 // negative regulation of female receptivity // inferred from electronic annotation /// 0007625 // grooming behavior // inferred from electronic annotation /// 0008015 // blood circulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010460 // positive regulation of heart rate // inferred from electronic annotation /// 0014049 // positive regulation of glutamate secretion // inferred from electronic annotation /// 0014902 // myotube differentiation // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0021537 // telencephalon development // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0031394 // positive regulation of prostaglandin biosynthetic process // inferred from electronic annotation /// 0032849 // positive regulation of cellular pH reduction // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0035815 // positive regulation of renal sodium excretion // inferred from electronic annotation /// 0042631 // cellular response to water deprivation // inferred from electronic annotation /// 0042711 // maternal behavior // inferred from electronic annotation /// 0042713 // sperm ejaculation // inferred from electronic annotation /// 0043084 // penile erection // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051970 // negative regulation of transmission of nerve impulse // inferred from electronic annotation","0005768 // endosome // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation","0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005000 // vasopressin receptor activity // inferred from electronic annotation /// 0005080 // protein kinase C binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017046 // peptide hormone binding // inferred from electronic annotation /// 0031894 // V1A vasopressin receptor binding // inferred from electronic annotation","GPCRDB_Class_A_Rhodopsin-like // GenMAPP /// Peptide_GPCRs // GenMAPP","IPR000276 // G protein-coupled receptor, rhodopsin-like // 4.1E-54 /// IPR015076 // Domain of unknown function DUF1856 // 2.9E-21 /// IPR019424 // 7TM GPCR, olfactory receptor/chemoreceptor Srsx // 1.4E-10 /// IPR019426 // 7TM GPCR, serpentine receptor class v (Srv) // 1.5E-9"
"238967_at",2.477334375,2.097498226,1.016027914,"UP","AI924046","chr3:190032351-190032987 (-) // 69.24 // q28","---","---","---","---","---","---","---","---","---","---","---","---"
"239006_at",-2.63391659,-1.866344722,-2.553693998,"DOWN","AI758950","chr8:92409938-92410378 (+) // 93.02 // q21.3","solute carrier family 26 (anion exchanger), member 7","SLC26A7","ENSG00000147606 /// OTTHUMG00000164062","115111","608479","NP_001269285 /// NP_001269286 /// NP_439897 /// NP_599028","NM_001282356 /// NM_001282357 /// NM_052832 /// NM_134266","0001696 // gastric acid secretion // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // traceable author statement /// 0006820 // anion transport // inferred from direct assay /// 0006821 // chloride transport // inferred from direct assay /// 0008272 // sulfate transport // inferred from direct assay /// 0015701 // bicarbonate transport // inferred from sequence or structural similarity /// 0019532 // oxalate transport // inferred from direct assay /// 0055085 // transmembrane transport // traceable author statement /// 1902358 // sulfate transmembrane transport // inferred from direct assay /// 1902358 // sulfate transmembrane transport // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from direct assay /// 1902476 // chloride transmembrane transport // inferred from electronic annotation","0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from mutant phenotype /// 0055038 // recycling endosome membrane // inferred from electronic annotation","0005253 // anion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from direct assay /// 0015106 // bicarbonate transmembrane transporter activity // inferred from sequence or structural similarity /// 0015116 // sulfate transmembrane transporter activity // inferred from direct assay /// 0015301 // anion:anion antiporter activity // inferred from electronic annotation /// 0019531 // oxalate transmembrane transporter activity // inferred from direct assay","---","IPR002645 // STAS domain // 1.4E-22 /// IPR011547 // Sulphate transporter // 1.1E-67"
"239183_at",-2.100351585,-1.510911011,-2.1920987,"DOWN","W67461","chr1:178818673-178819322 (-) // 97.89 // q25.2","angiopoietin-like 1","ANGPTL1","ENSG00000116194 /// OTTHUMG00000035075","9068","603874","NP_004664 /// XP_005245634","NM_004673 /// XM_005245577 /// XR_241102","0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation","0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005102 // receptor binding // inferred from electronic annotation","---","IPR002181 // Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain // 2.5E-78"
"239262_at",-1.433892671,-1.190438923,-1.231984785,"DOWN","AI498395","chr11:86620943-86621413 (-) // 96.51 // q14.2","---","---","---","---","---","---","---","---","---","---","---","---"
"239297_at",-2.039063575,-1.653413378,-1.805161882,"DOWN","BE932011","chr8:12886663-12887286 (+) // 90.61 // p22","KIAA1456 /// uncharacterized LOC101927137","KIAA1456 /// LOC101927137","ENSG00000250305 /// OTTHUMG00000165477","57604 /// 101927137","615666","NP_001093147 /// NP_065895 /// XP_005273641 /// XP_005273642 /// XP_005273643 /// XP_005273644 /// XP_005273645 /// XP_005273646 /// XP_005273647 /// XP_005273648 /// XP_005273649 /// XP_005273650 /// XP_006716434 /// XP_006716435 /// XP_006716436 /// XP_006716437 /// XP_006716438 /// XP_006716439 /// XP_006716440","NM_001099677 /// NM_020844 /// XM_005273584 /// XM_005273585 /// XM_005273586 /// XM_005273587 /// XM_005273588 /// XM_005273589 /// XM_005273590 /// XM_005273591 /// XM_005273592 /// XM_005273593 /// XM_006716371 /// XM_006716372 /// XM_006716373 /// XM_006716374 /// XM_006716375 /// XM_006716376 /// XM_006716377 /// XR_246167 /// XR_246168 /// XR_246169 /// XR_246170 /// XR_246171 /// XR_246172 /// XR_246173 /// XR_252798 /// XR_252799 /// XR_252800 /// XR_252801 /// XR_252802 /// XR_252803 /// XR_252804 /// XR_428788 /// XR_428789 /// XR_428790 /// XR_428791 /// XR_428792 /// XR_428793 /// XR_428794 /// XR_428795 /// XR_428796 /// XR_432624 /// XR_432625 /// XR_432626 /// XR_432627 /// XR_432628 /// XR_432629 /// XR_432630 /// XR_432631 /// XR_432632","0008152 // metabolic process // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation","---","0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation","---","IPR004033 // UbiE/COQ5 methyltransferase // 1.2E-9 /// IPR007823 // Methyltransferase-related // 2.2E-9 /// IPR013216 // Methyltransferase type 11 // 1.3E-20 /// IPR013217 // Methyltransferase type 12 // 5.4E-13"
"239353_at",1.513033643,1.100473649,1.452706791,"UP","AW204033","chr5:146764755-146765702 (+) // 66.82 // q32","serine/threonine kinase 32A","STK32A","ENSG00000169302 /// OTTHUMG00000163411","202374","---","NP_001106195 /// NP_001274669 /// NP_659438","NM_001112724 /// NM_001287740 /// NM_145001","0006468 // protein phosphorylation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation","---","0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000719 // Protein kinase domain // 2.3E-67 /// IPR001245 // Serine-threonine/tyrosine-protein kinase catalytic domain // 1.3E-43"
"239381_at",1.097763381,1.294552274,4.533526441,"UP","AU155415","chr19:51479734-51480160 (-) // 36.12 // q13.41","kallikrein-related peptidase 7","KLK7","ENSG00000169035 /// OTTHUMG00000182917","5650","604438","NP_001193982 /// NP_001230055 /// NP_005037 /// NP_644806","NM_001207053 /// NM_001243126 /// NM_005046 /// NM_139277","0006508 // proteolysis // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement","0005576 // extracellular region // traceable author statement /// 0097209 // epidermal lamellar body // inferred from direct assay","0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation","---","IPR001254 // Peptidase S1 // 2.4E-72"
"240236_at",-2.967991261,-1.573163448,-2.465778782,"DOWN","N50117","chr3:121143257-121143607 (+) // 95.11 // q13.33","syntaxin binding protein 5-like","STXBP5L","ENSG00000145087 /// OTTHUMG00000159426","9515","609381","NP_055795 /// XP_005247964 /// XP_006713888 /// XP_006713889","NM_014980 /// XM_005247907 /// XM_006713825 /// XM_006713826","0006810 // transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0017157 // regulation of exocytosis // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from electronic annotation","0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","0005515 // protein binding // inferred from electronic annotation /// 0019905 // syntaxin binding // inferred from electronic annotation","---","IPR001680 // WD40 repeat // 2.1E-5 /// IPR001680 // WD40 repeat // 1.4E-6 /// IPR013577 // Lethal giant larvae homologue 2 // 3.7E-45 /// IPR013905 // Lethal giant larvae (Lgl)-like, C-terminal domain // 1.7E-9"
"240502_at",1.359236592,2.001083398,1.396744307,"UP","AW015920","chr15:44410213-44410664 (-) // 96.15 // q15.3","---","---","---","---","---","---","---","---","---","---","---","---"
"240770_at",-1.440634144,-1.794133449,-3.060004948,"DOWN","AW058459","chr5:72427203-72427641 (+) // 88.07 // q13.2","transmembrane protein 171","TMEM171","ENSG00000157111 /// OTTHUMG00000131269","134285","---","NP_001154814 /// NP_775761 /// XP_005248488 /// XP_005248489","NM_001161342 /// NM_173490 /// XM_005248431 /// XM_005248432","---","0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","---","---","---"
"241017_at",-1.797683722,-1.219288169,-1.38465458,"DOWN","AA779927","chr2:101640001-101640499 (+) // 99.0 // q11.2","ribosomal protein L31 /// TBC1 domain family, member 8 (with GRAM domain)","RPL31 /// TBC1D8","ENSG00000071082 /// OTTHUMG00000130687","6160 /// 11138","---","NP_000984 /// NP_001092047 /// NP_001093163 /// NP_001095896 /// XP_005263919 /// XP_005263920 /// XP_005263921","NM_000993 /// NM_001098577 /// NM_001099693 /// NM_001102426 /// NM_007063 /// XM_005263862 /// XM_005263863 /// XM_005263864","0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0006412 // translation // non-traceable author statement /// 0006412 // translation // traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // traceable author statement /// 0006415 // translational termination // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // traceable author statement /// 0008015 // blood circulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0019058 // viral life cycle // traceable author statement /// 0019083 // viral transcription // traceable author statement /// 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation /// 0032851 // positive regulation of Rab GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement","0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0044822 // poly(A) RNA binding // inferred from direct assay","Cell_cycle_KEGG // GenMAPP /// Ribosomal_Proteins // GenMAPP /// Ribosomal_Proteins // GenMAPP /// Ribosomal_Proteins // GenMAPP","IPR000054 // Ribosomal protein L31e // 6.7E-46"
"241031_at",1.067021168,1.166495489,2.190839518,"UP","BE218239","chr15:62362676-62363183 (+) // 100.0 // q22.2","C2 calcium-dependent domain containing 4A","C2CD4A","ENSG00000198535 /// OTTHUMG00000171942","145741","610343","NP_997205","NM_207322","---","0005634 // nucleus // inferred from electronic annotation","0005515 // protein binding // inferred from electronic annotation","---","---"
"241470_x_at",-1.91384639,-1.469585961,-1.934353276,"DOWN","R97781","chr12:86194480-86194775 (-) // 88.26 // q21.31","Ras association (RalGDS/AF-6) domain family (N-terminal) member 9","RASSF9","ENSG00000198774 /// OTTHUMG00000169831","9182","610383","NP_005438","NM_005447","0006605 // protein targeting // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0016197 // endosomal transport // non-traceable author statement","0005768 // endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0012510 // trans-Golgi network transport vesicle membrane // inferred from direct assay","0005215 // transporter activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction","---","---"
"241672_at",-2.843414384,-1.824088806,-2.487073998,"DOWN","BG413606","chr13:37271527-37271976 (+) // 94.29 // q13.3","serine-rich and transmembrane domain containing 1","SERTM1","ENSG00000180440 /// OTTHUMG00000016735","400120","---","NP_982276","NM_203451","---","0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation","---","---","---"
"241884_at",1.322641166,1.037396215,1.084574754,"UP","AI057052","chr7:30505285-30505580 (-) // 96.72 // p14.3","---","---","---","---","---","---","---","---","---","---","---","---"
"241898_at",2.057766721,2.195888666,3.454313488,"UP","AA991267","chr3:185224049-185224489 (-) // 66.67 // q27.2","lipase, member H","LIPH","ENSG00000163898 /// OTTHUMG00000156657","200879","604379 /// 607365","NP_640341 /// XP_006713592 /// XP_006713593","NM_139248 /// XM_006713529 /// XM_006713530","0006629 // lipid metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from direct assay","0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation","0003824 // catalytic activity // inferred from electronic annotation /// 0004620 // phospholipase activity // inferred from direct assay /// 0008201 // heparin binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation","Statin_Pathway_PharmGKB // GenMAPP","IPR013818 // Lipase, N-terminal // 6.6E-83"
"241981_at",2.70668446,1.649052433,2.024922812,"UP","AW291369","chr17:66531257-66531713 (-) // 97.44 // q24.2","family with sequence similarity 20, member A","FAM20A","ENSG00000108950 /// OTTHUMG00000180152","54757","611062 /// 614253","NP_001230675 /// NP_060035 /// XP_006722021 /// XP_006722022 /// XP_006722023","NM_001243746 /// NM_017565 /// NR_027751 /// XM_006721958 /// XM_006721959 /// XM_006721960 /// XR_429905","0044691 // tooth eruption // inferred from mutant phenotype /// 0055074 // calcium ion homeostasis // inferred from mutant phenotype /// 0070166 // enamel mineralization // inferred from mutant phenotype","0005576 // extracellular region // inferred from electronic annotation /// 0005623 // cell // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay","---","---","---"
"242057_at",-1.276705288,-1.095553747,-1.506417635,"DOWN","AI301859","chr7:143913279-143914164 (+) // 93.99 // q35 /// chr7:144031012-144031897 (-) // 93.99 // q35","---","---","---","---","---","---","---","---","---","---","---","---"
"242093_at",3.717911655,2.907906916,3.336874472,"UP","AW263497","chrX:37987684-37988064 (+) // 96.94 // p11.4","synaptotagmin-like 5","SYTL5","ENSG00000147041 /// OTTHUMG00000033176","94122","---","NP_001156806 /// NP_001156807 /// NP_620135","NM_001163334 /// NM_001163335 /// NM_138780","0006886 // intracellular protein transport // inferred from electronic annotation /// 0006887 // exocytosis // inferred from electronic annotation","0016020 // membrane // inferred from electronic annotation","0005515 // protein binding // inferred from physical interaction /// 0017137 // Rab GTPase binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","IPR000008 // C2 domain // 1.8E-19 /// IPR000008 // C2 domain // 1.2E-23 /// IPR000008 // C2 domain // 1.8E-19 /// IPR000008 // C2 domain // 1.3E-23"
"242344_at",5.264201219,4.777348406,4.241216757,"UP","AA772920","chr5:160715511-160716008 (-) // 95.18 // q34","gamma-aminobutyric acid (GABA) A receptor, beta 2","GABRB2","ENSG00000145864 /// OTTHUMG00000130349","2561","600232","NP_000804 /// NP_068711","NM_000813 /// NM_021911","0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007214 // gamma-aminobutyric acid signaling pathway // traceable author statement /// 0007268 // synaptic transmission // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0043523 // regulation of neuron apoptotic process // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0048666 // neuron development // inferred from electronic annotation /// 0051932 // synaptic transmission, GABAergic // inferred from sequence or structural similarity /// 0055085 // transmembrane transport // traceable author statement /// 0060119 // inner ear receptor cell development // inferred from electronic annotation /// 0060384 // innervation // inferred from electronic annotation /// 0071420 // cellular response to histamine // inferred from sequence or structural similarity /// 0090102 // cochlea development // inferred from electronic annotation /// 1901215 // negative regulation of neuron death // inferred from electronic annotation /// 1902476 // chloride transmembrane transport // inferred from electronic annotation","0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0034707 // chloride channel complex // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 1902711 // GABA-A receptor complex // inferred from sequence or structural similarity","0004890 // GABA-A receptor activity // inferred from sequence or structural similarity /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005230 // extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005237 // inhibitory extracellular ligand-gated ion channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation","---","IPR006029 // Neurotransmitter-gated ion-channel transmembrane domain // 9.7E-57 /// IPR006202 // Neurotransmitter-gated ion-channel ligand-binding // 6.0E-56"
"242680_at",-2.104265708,-2.445894306,-1.935858927,"DOWN","AW242409","chr12:63536538-63537055 (-) // 90.67 // q14.2","arginine vasopressin receptor 1A","AVPR1A","ENSG00000166148 /// OTTHUMG00000169980","552","600821","NP_000697 /// XP_005269059","NM_000706 /// XM_005269002","0001992 // regulation of systemic arterial blood pressure by vasopressin // inferred from electronic annotation /// 0002125 // maternal aggressive behavior // inferred from electronic annotation /// 0003084 // positive regulation of systemic arterial blood pressure // inferred from electronic annotation /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // traceable author statement /// 0007204 // positive regulation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007621 // negative regulation of female receptivity // inferred from electronic annotation /// 0007625 // grooming behavior // inferred from electronic annotation /// 0008015 // blood circulation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0010035 // response to inorganic substance // inferred from electronic annotation /// 0010460 // positive regulation of heart rate // inferred from electronic annotation /// 0014049 // positive regulation of glutamate secretion // inferred from electronic annotation /// 0014902 // myotube differentiation // inferred from electronic annotation /// 0019722 // calcium-mediated signaling // inferred from electronic annotation /// 0021537 // telencephalon development // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0031394 // positive regulation of prostaglandin biosynthetic process // inferred from electronic annotation /// 0032849 // positive regulation of cellular pH reduction // inferred from electronic annotation /// 0035176 // social behavior // inferred from electronic annotation /// 0035815 // positive regulation of renal sodium excretion // inferred from electronic annotation /// 0042631 // cellular response to water deprivation // inferred from electronic annotation /// 0042711 // maternal behavior // inferred from electronic annotation /// 0042713 // sperm ejaculation // inferred from electronic annotation /// 0043084 // penile erection // inferred from electronic annotation /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0045907 // positive regulation of vasoconstriction // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051970 // negative regulation of transmission of nerve impulse // inferred from electronic annotation","0005768 // endosome // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation","0004871 // signal transducer activity // inferred from electronic annotation /// 0004930 // G-protein coupled receptor activity // inferred from electronic annotation /// 0005000 // vasopressin receptor activity // inferred from electronic annotation /// 0005080 // protein kinase C binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0017046 // peptide hormone binding // inferred from electronic annotation /// 0031894 // V1A vasopressin receptor binding // inferred from electronic annotation","GPCRDB_Class_A_Rhodopsin-like // GenMAPP /// Peptide_GPCRs // GenMAPP","IPR000276 // G protein-coupled receptor, rhodopsin-like // 4.1E-54 /// IPR015076 // Domain of unknown function DUF1856 // 2.9E-21 /// IPR019424 // 7TM GPCR, olfactory receptor/chemoreceptor Srsx // 1.4E-10 /// IPR019426 // 7TM GPCR, serpentine receptor class v (Srv) // 1.5E-9"
"242763_at",-1.07948326,-1.943627275,-2.000877775,"DOWN","N39188","chr8:110512339-110512750 (+) // 16.02 // q23.2","---","---","---","---","---","---","---","---","---","---","---","---"
"242883_at",-2.02043222,-2.066327031,-3.033016519,"DOWN","AW772596","chr2:241078442-241079787 (-) // 90.67 // q37.3","otospiralin","OTOS","ENSG00000178602 /// OTTHUMG00000133351","150677","607877","NP_683764","NM_148961","0007605 // sensory perception of sound // inferred from electronic annotation","0005576 // extracellular region // inferred from electronic annotation","---","---","---"
"242931_at",-1.431760403,-1.290501674,-1.425903408,"DOWN","AI218358","chrX:118156471-118156887 (+) // 98.11 // q24","---","---","---","---","---","---","---","---","---","---","---","---"
"242945_at",2.288476061,1.204849647,1.391439199,"UP","AI860568","chr17:66531823-66532436 (-) // 78.62 // q24.2","family with sequence similarity 20, member A","FAM20A","ENSG00000108950 /// OTTHUMG00000180152","54757","611062 /// 614253","NP_001230675 /// NP_060035 /// XP_006722021 /// XP_006722022 /// XP_006722023","NM_001243746 /// NM_017565 /// NR_027751 /// XM_006721958 /// XM_006721959 /// XM_006721960 /// XR_429905","0044691 // tooth eruption // inferred from mutant phenotype /// 0055074 // calcium ion homeostasis // inferred from mutant phenotype /// 0070166 // enamel mineralization // inferred from mutant phenotype","0005576 // extracellular region // inferred from electronic annotation /// 0005623 // cell // inferred from sequence or structural similarity /// 0070062 // extracellular vesicular exosome // inferred from direct assay","---","---","---"
"242979_at",-1.380694624,-1.802212174,-1.447342866,"DOWN","AI474666","chr2:227596033-227596685 (-) // 94.74 // q36.3","insulin receptor substrate 1","IRS1","ENSG00000169047 /// OTTHUMG00000133179","3667","125853 /// 147545","NP_005535 /// XP_005246591 /// XP_006712575","NM_005544 /// XM_005246534 /// XM_006712512","0002053 // positive regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008284 // positive regulation of cell proliferation // non-traceable author statement /// 0008286 // insulin receptor signaling pathway // inferred from direct assay /// 0008286 // insulin receptor signaling pathway // inferred from mutant phenotype /// 0008286 // insulin receptor signaling pathway // inferred from physical interaction /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010907 // positive regulation of glucose metabolic process // inferred from mutant phenotype /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from direct assay /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030879 // mammary gland development // inferred from electronic annotation /// 0032000 // positive regulation of fatty acid beta-oxidation // inferred from mutant phenotype /// 0032868 // response to insulin // inferred from direct assay /// 0032869 // cellular response to insulin stimulus // inferred from mutant phenotype /// 0034504 // protein localization to nucleus // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0042593 // glucose homeostasis // traceable author statement /// 0043434 // response to peptide hormone // inferred from sequence or structural similarity /// 0043491 // protein kinase B signaling // inferred from electronic annotation /// 0043552 // positive regulation of phosphatidylinositol 3-kinase activity // inferred from sequence or structural similarity /// 0045087 // innate immune response // traceable author statement /// 0045725 // positive regulation of glycogen biosynthetic process // inferred from mutant phenotype /// 0045725 // positive regulation of glycogen biosynthetic process // non-traceable author statement /// 0046326 // positive regulation of glucose import // inferred from mutant phenotype /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0046628 // positive regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0046676 // negative regulation of insulin secretion // inferred from direct assay /// 0048009 // insulin-like growth factor receptor signaling pathway // inferred from physical interaction /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0060397 // JAK-STAT cascade involved in growth hormone signaling pathway // traceable author statement /// 2001275 // positive regulation of glucose import in response to insulin stimulus // inferred from direct assay","0005634 // nucleus // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005899 // insulin receptor complex // inferred from sequence or structural similarity /// 0005901 // caveola // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from sequence or structural similarity","0004871 // signal transducer activity // inferred from electronic annotation /// 0005068 // transmembrane receptor protein tyrosine kinase adaptor activity // inferred from sequence or structural similarity /// 0005080 // protein kinase C binding // inferred from sequence or structural similarity /// 0005158 // insulin receptor binding // inferred from physical interaction /// 0005159 // insulin-like growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0042169 // SH2 domain binding // inferred from sequence or structural similarity /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from physical interaction /// 0043548 // phosphatidylinositol 3-kinase binding // inferred from sequence or structural similarity","---","IPR001849 // Pleckstrin homology domain // 3.3E-17 /// IPR002404 // Insulin receptor substrate-1, PTB // 3.6E-33"
"243172_at",1.799502865,1.615428136,1.534912587,"UP","AI079944","chrX:50331939-50332378 (-) // 61.8 // p11.22","Homo sapiens cDNA FLJ36394 fis, clone THYMU2009104.","AX748273","---","---","---","---","---","---","---","---","---","---"
"243278_at",-2.769582902,-2.559436879,-1.963019721,"DOWN","AW291402","chr7:114332549-114333058 (+) // 100.0 // q31.1","forkhead box P2","FOXP2","ENSG00000128573 /// OTTHUMG00000023131","93986","602081 /// 605317","NP_001166237 /// NP_001166238 /// NP_055306 /// NP_683696 /// NP_683697 /// NP_683698 /// XP_006716242 /// XP_006716243","NM_001172766 /// NM_001172767 /// NM_014491 /// NM_148898 /// NM_148899 /// NM_148900 /// NR_033766 /// NR_033767 /// XM_006716179 /// XM_006716180 /// XR_428189","0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0002053 // positive regulation of mesenchymal cell proliferation // not recorded /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007389 // pattern specification process // not recorded /// 0007519 // skeletal muscle tissue development // not recorded /// 0009790 // embryo development // inferred from electronic annotation /// 0009791 // post-embryonic development // not recorded /// 0021549 // cerebellum development // not recorded /// 0021757 // caudate nucleus development // inferred from mutant phenotype /// 0021758 // putamen development // inferred from mutant phenotype /// 0021987 // cerebral cortex development // inferred from expression pattern /// 0030324 // lung development // inferred from electronic annotation /// 0040007 // growth // not recorded /// 0042297 // vocal learning // not recorded /// 0043010 // camera-type eye development // not recorded /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048286 // lung alveolus development // not recorded /// 0048745 // smooth muscle tissue development // not recorded /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation /// 0060013 // righting reflex // not recorded /// 0060501 // positive regulation of epithelial cell proliferation involved in lung morphogenesis // not recorded","0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // not recorded","0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // not recorded /// 0003700 // sequence-specific DNA binding transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0008301 // DNA binding, bending // not recorded /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // not recorded","---","IPR001766 // Transcription factor, fork head // 2.0E-29 /// IPR001766 // Transcription factor, fork head // 2.0E-29 /// IPR001766 // Transcription factor, fork head // 4.3E-24"
"243386_at",-1.455039633,-1.239724701,-1.833006857,"DOWN","AI085338","chr1:10696666-10697246 (-) // 62.68 // p36.22","castor zinc finger 1","CASZ1","ENSG00000130940 /// OTTHUMG00000002035","54897","609895","NP_001073312 /// NP_060236 /// XP_005263536 /// XP_006710775","NM_001039183 /// NM_001079843 /// NM_017766 /// XM_005263479 /// XM_006710712","0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation","0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay","0003677 // DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","---","---"
"243681_at",-1.671142406,-1.884943511,-1.960368588,"DOWN","AA464273","chr11:70313958-70314249 (-) // 100.0 // q13.3","SH3 and multiple ankyrin repeat domains 2","SHANK2","ENSG00000162105 /// ENSG00000268430 /// OTTHUMG00000154615","22941","603290 /// 613436","NP_036441 /// NP_573573 /// XP_005277987 /// XP_005277989 /// XP_006718540 /// XP_006718541","NM_012309 /// NM_133266 /// NR_110766 /// XM_005277930 /// XM_005277932 /// XM_006718477 /// XM_006718478","0007416 // synapse assembly // inferred from sequence or structural similarity /// 0007612 // learning // inferred from mutant phenotype /// 0030534 // adult behavior // inferred from mutant phenotype /// 0035176 // social behavior // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0060291 // long-term synaptic potentiation // inferred from sequence or structural similarity /// 0060292 // long term synaptic depression // inferred from sequence or structural similarity /// 0071625 // vocalization behavior // inferred from mutant phenotype","0001750 // photoreceptor outer segment // inferred from sequence or structural similarity /// 0001917 // photoreceptor inner segment // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005883 // neurofilament // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0008328 // ionotropic glutamate receptor complex // inferred from sequence or structural similarity /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from sequence or structural similarity /// 0030054 // cell junction // inferred from electronic annotation /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031526 // brush border membrane // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from sequence or structural similarity /// 0043025 // neuronal cell body // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from sequence or structural similarity /// 0060170 // ciliary membrane // inferred from sequence or structural similarity","0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation /// 0030160 // GKAP/Homer scaffold activity // non-traceable author statement /// 0035255 // ionotropic glutamate receptor binding // inferred from sequence or structural similarity","---","IPR001452 // SH3 domain // 3.2E-9 /// IPR001452 // SH3 domain // 5.0E-9 /// IPR001478 // PDZ domain // 6.9E-12 /// IPR001478 // PDZ domain // 1.4E-11 /// IPR001478 // PDZ domain // 6.9E-12 /// IPR001478 // PDZ domain // 2.2E-11 /// IPR011510 // Sterile alpha motif, type 2 // 3.5E-22 /// IPR011510 // Sterile alpha motif, type 2 // 7.0E-22 /// IPR011510 // Sterile alpha motif, type 2 // 3.5E-22 /// IPR011510 // Sterile alpha motif, type 2 // 1.1E-21 /// IPR011511 // Variant SH3 domain // 1.0E-15 /// IPR011511 // Variant SH3 domain // 1.6E-15 /// IPR021129 // Sterile alpha motif, type 1 // 2.8E-23 /// IPR021129 // Sterile alpha motif, type 1 // 5.7E-23 /// IPR021129 // Sterile alpha motif, type 1 // 2.8E-23 /// IPR021129 // Sterile alpha motif, type 1 // 8.8E-23"
"244297_at",-1.372603835,-1.83043379,-1.774841916,"DOWN","AI806762","chr9:38541452-38543614 (-) // 82.73 // p13.1","ankyrin repeat domain 18A","ANKRD18A","ENSG00000273036 /// ENSG00000273170 /// OTTHUMG00000186324 /// OTTHUMG00000186350","253650","---","NP_671728 /// XP_006716812","NM_147195 /// XM_006716749","---","---","---","---","IPR021885 // Protein of unknown function DUF3496 // 7.9E-49 /// IPR021885 // Protein of unknown function DUF3496 // 1.9E-48"
"244675_at",-2.919241623,-1.772378277,-1.424617926,"DOWN","R37101","chr1:182610950-182611295 (-) // 93.46 // q25.3","regulator of G-protein signaling 8","RGS8","ENSG00000261185 /// OTTHUMG00000176159","85397","607189","NP_001095920 /// NP_203131 /// XP_005245612 /// XP_006711660","NM_001102450 /// NM_033345 /// XM_005245555 /// XM_006711597","0009968 // negative regulation of signal transduction // inferred from electronic annotation /// 0038032 // termination of G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // not recorded","0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // not recorded","0005096 // GTPase activator activity // not recorded","---","---"
"32128_at",1.550665869,2.26811676,1.759742482,"UP","Y13710","chr17:34391630-34398829 (+) // 96.25 // q12","chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)","CCL18","---","6362","603757","NP_002979","NM_002988","0006935 // chemotaxis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007154 // cell communication // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0009607 // response to biotic stimulus // traceable author statement /// 0060326 // cell chemotaxis // inferred from electronic annotation /// 0060326 // cell chemotaxis // traceable author statement","0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation","0005125 // cytokine activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008009 // chemokine activity // inferred from electronic annotation","---","---"
"33323_r_at",2.289871375,1.521114219,2.307707437,"UP","X57348","chr1:27189648-27190947 (+) // 58.96 // p36.11","stratifin","SFN","ENSG00000175793 /// OTTHUMG00000004093","2810","601290","NP_006133","NM_006142","0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from direct assay /// 0006469 // negative regulation of protein kinase activity // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 0010482 // regulation of epidermal cell division // inferred from sequence or structural similarity /// 0030216 // keratinocyte differentiation // inferred from electronic annotation /// 0030307 // positive regulation of cell growth // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043588 // skin development // inferred from electronic annotation /// 0043616 // keratinocyte proliferation // inferred from electronic annotation /// 0045606 // positive regulation of epidermal cell differentiation // inferred from sequence or structural similarity /// 0046827 // positive regulation of protein export from nucleus // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0061024 // membrane organization // traceable author statement /// 0061436 // establishment of skin barrier // inferred from sequence or structural similarity /// 0071901 // negative regulation of protein serine/threonine kinase activity // traceable author statement /// 0097193 // intrinsic apoptotic signaling pathway // traceable author statement /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // traceable author statement","0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0030659 // cytoplasmic vesicle membrane // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay","0005515 // protein binding // inferred from physical interaction /// 0008426 // protein kinase C inhibitor activity // traceable author statement /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation","Calcium_regulation_in_cardiac_cells // GenMAPP /// Smooth_muscle_contraction // GenMAPP","IPR023410 // 14-3-3 domain // 1.9E-111"
"37004_at",2.781860632,3.690260352,3.767892388,"UP","J02761","chr2:85886032-85894300 (-) // 71.94 // p11.2","surfactant protein B","SFTPB","ENSG00000168878 /// OTTHUMG00000130181","6439","178640 /// 265120","NP_000533 /// NP_942140 /// XP_005264544 /// XP_005264545 /// XP_005264546 /// XP_005264547 /// XP_006712139","NM_000542 /// NM_198843 /// XM_005264487 /// XM_005264488 /// XM_005264489 /// XM_005264490 /// XM_006712076","0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // inferred from electronic annotation /// 0007585 // respiratory gaseous exchange // inferred from electronic annotation /// 0009887 // organ morphogenesis // traceable author statement","0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation","---","---","IPR003119 // Saposin type A // 1.7E-18 /// IPR003119 // Saposin type A // 1.8E-18 /// IPR007856 // Saposin-like type B, 1 // 3.8E-9 /// IPR007856 // Saposin-like type B, 1 // 4.0E-9 /// IPR008138 // Saposin-like type B, 2 // 5.7E-14 /// IPR008138 // Saposin-like type B, 2 // 6.1E-8 /// IPR008138 // Saposin-like type B, 2 // 2.7E-14 /// IPR008138 // Saposin-like type B, 2 // 6.0E-14 /// IPR008138 // Saposin-like type B, 2 // 6.3E-8 /// IPR008138 // Saposin-like type B, 2 // 2.8E-14"
"37408_at",1.97149266,1.350521939,2.001866383,"UP","AB014609","chr17:60705042-60770958 (+) // 94.3 // q23.2","mannose receptor, C type 2","MRC2","ENSG00000011028 /// OTTHUMG00000179178","9902","612264","NP_006030","NM_006039","0001649 // osteoblast differentiation // inferred from direct assay /// 0006897 // endocytosis // inferred from electronic annotation /// 0030574 // collagen catabolic process // inferred from direct assay","0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation","0005515 // protein binding // inferred from physical interaction /// 0005518 // collagen binding // inferred from direct assay /// 0030246 // carbohydrate binding // inferred from electronic annotation","---","IPR000562 // Fibronectin, type II, collagen-binding // 3.9E-19 /// IPR001304 // C-type lectin // 1.6E-29 /// IPR001304 // C-type lectin // 1.2E-30 /// IPR001304 // C-type lectin // 2.1E-23 /// IPR001304 // C-type lectin // 8.3E-19 /// IPR001304 // C-type lectin // 2.0E-25 /// IPR001304 // C-type lectin // 1.1E-22 /// IPR001304 // C-type lectin // 1.5E-17 /// IPR001304 // C-type lectin // 4.8E-14 /// IPR001304 // C-type lectin // 1.3E-15 /// IPR008646 // Herpesvirus UL45-like // 5.9E-8"
"37512_at",-2.197570743,-1.795396738,-1.529438955,"DOWN","U89281","chr12:57157117-57181571 (+) // 75.65 // q13.3","hydroxysteroid (17-beta) dehydrogenase 6","HSD17B6","ENSG00000025423 /// OTTHUMG00000170854","8630","606623","NP_003716 /// XP_005269264 /// XP_005269265 /// XP_005269266 /// XP_006719735","NM_003725 /// XM_005269207 /// XM_005269208 /// XM_005269209 /// XM_006719672 /// XR_245961","0006629 // lipid metabolic process // inferred from electronic annotation /// 0006702 // androgen biosynthetic process // non-traceable author statement /// 0006710 // androgen catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0055114 // oxidation-reduction process // inferred from electronic annotation","0005622 // intracellular // non-traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031090 // organelle membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation","0003824 // catalytic activity // traceable author statement /// 0004303 // estradiol 17-beta-dehydrogenase activity // inferred from electronic annotation /// 0004745 // retinol dehydrogenase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // non-traceable author statement /// 0047035 // testosterone dehydrogenase (NAD+) activity // inferred from electronic annotation","---","IPR002198 // Short-chain dehydrogenase/reductase SDR // 7.0E-26"
"37892_at",2.288304036,1.321626398,2.342692845,"UP","J04177","chr1:103342947-103573895 (-) // 91.11 // p21.1","collagen, type XI, alpha 1","COL11A1","ENSG00000060718 /// OTTHUMG00000010872","1301","120280 /// 154780 /// 228520 /// 603932 /// 604841","NP_001177638 /// NP_001845 /// NP_542196 /// NP_542197","NM_001190709 /// NM_001854 /// NM_080629 /// NM_080630","0001502 // cartilage condensation // inferred from electronic annotation /// 0002063 // chondrocyte development // inferred from electronic annotation /// 0003007 // heart morphogenesis // inferred from electronic annotation /// 0006029 // proteoglycan metabolic process // inferred from electronic annotation /// 0007601 // visual perception // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // traceable author statement /// 0030198 // extracellular matrix organization // non-traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0030199 // collagen fibril organization // non-traceable author statement /// 0030574 // collagen catabolic process // traceable author statement /// 0035989 // tendon development // inferred from electronic annotation /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048705 // skeletal system morphogenesis // inferred from electronic annotation /// 0050910 // detection of mechanical stimulus involved in sensory perception of sound // inferred from mutant phenotype /// 0051216 // cartilage development // inferred from electronic annotation /// 0055010 // ventricular cardiac muscle tissue morphogenesis // inferred from electronic annotation","0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005592 // collagen type XI trimer // inferred from direct assay /// 0005592 // collagen type XI trimer // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0031012 // extracellular matrix // inferred from electronic annotation","0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0030674 // protein binding, bridging // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050840 // extracellular matrix binding // non-traceable author statement","---","IPR000885 // Fibrillar collagen, C-terminal // 1.1E-87 /// IPR000885 // Fibrillar collagen, C-terminal // 1.1E-87 /// IPR000885 // Fibrillar collagen, C-terminal // 1.0E-87 /// IPR001791 // Laminin G domain // 2.1E-15 /// IPR001791 // Laminin G domain // 2.0E-15 /// IPR008160 // Collagen triple helix repeat // 2.4E-11 /// IPR008160 // Collagen triple helix repeat // 3.9E-11 /// IPR008160 // Collagen triple helix repeat // 4.8E-9 /// IPR008160 // Collagen triple helix repeat // 2.3E-10 /// IPR008160 // Collagen triple helix repeat // 8.9E-11 /// IPR008160 // Collagen triple helix repeat // 1.8E-9 /// IPR008160 // Collagen triple helix repeat // 3.3E-9 /// IPR008160 // Collagen triple helix repeat // 5.4E-11 /// IPR008160 // Collagen triple helix repeat // 2.4E-11 /// IPR008160 // Collagen triple helix repeat // 4.2E-11 /// IPR008160 // Collagen triple helix repeat // 1.1E-10 /// IPR008160 // Collagen triple helix repeat // 2.3E-10 /// IPR008160 // Collagen triple helix repeat // 5.4E-9 /// IPR008160 // Collagen triple helix repeat // 4.9E-9 /// IPR008160 // Collagen triple helix repeat // 1.9E-9 /// IPR008160 // Collagen triple helix repeat // 3.9E-9 /// IPR008160 // Collagen triple helix repeat // 3.6E-11 /// IPR008160 // Collagen triple helix repeat // 2.3E-11 /// IPR008160 // Collagen triple helix repeat // 3.2E-11 /// IPR008160 // Collagen triple helix repeat // 1.2E-11 /// IPR008160 // Collagen triple helix repeat // 3.7E-11"
"43427_at",-1.274790576,-1.051289686,-1.38648922,"DOWN","AI970898","chr12:109705647-109706028 (+) // 99.74 // q24.11","acetyl-CoA carboxylase beta","ACACB","ENSG00000076555 /// OTTHUMG00000169250","32","601557","NP_001084 /// XP_005253933 /// XP_006719428 /// XP_006719429 /// XP_006719430","NM_001093 /// XM_005253876 /// XM_006719365 /// XM_006719366 /// XM_006719367 /// XR_243001 /// XR_429096 /// XR_429097 /// XR_429098","0006084 // acetyl-CoA metabolic process // inferred from direct assay /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006768 // biotin metabolic process // traceable author statement /// 0006853 // carnitine shuttle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0031325 // positive regulation of cellular metabolic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051289 // protein homotetramerization // inferred from direct assay /// 2001295 // malonyl-CoA biosynthetic process // inferred from electronic annotation","0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation","0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003989 // acetyl-CoA carboxylase activity // inferred from direct assay /// 0004075 // biotin carboxylase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0009374 // biotin binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","Fatty_Acid_Synthesis // GenMAPP /// PWY-4381 // HumanCyc /// PWY0-1264 // HumanCyc","IPR000022 // Carboxyl transferase // 5.3E-181 /// IPR000089 // Biotin/lipoyl attachment // 1.4E-17 /// IPR005479 // Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain // 3.2E-52 /// IPR005481 // Carbamoyl-phosphate synthase, large subunit, N-terminal // 4.9E-31 /// IPR005482 // Biotin carboxylase, C-terminal // 2.2E-25 /// IPR013537 // Acetyl-CoA carboxylase, central domain // 7.8E-251"
"49452_at",-1.389917503,-1.178052474,-1.422999204,"DOWN","AI057637","chr12:109705008-109706031 (+) // 66.94 // q24.11","acetyl-CoA carboxylase beta","ACACB","ENSG00000076555 /// OTTHUMG00000169250","32","601557","NP_001084 /// XP_005253933 /// XP_006719428 /// XP_006719429 /// XP_006719430","NM_001093 /// XM_005253876 /// XM_006719365 /// XM_006719366 /// XM_006719367 /// XR_243001 /// XR_429096 /// XR_429097 /// XR_429098","0006084 // acetyl-CoA metabolic process // inferred from direct assay /// 0006112 // energy reserve metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006766 // vitamin metabolic process // traceable author statement /// 0006767 // water-soluble vitamin metabolic process // traceable author statement /// 0006768 // biotin metabolic process // traceable author statement /// 0006853 // carnitine shuttle // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0031325 // positive regulation of cellular metabolic process // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051289 // protein homotetramerization // inferred from direct assay /// 2001295 // malonyl-CoA biosynthetic process // inferred from electronic annotation","0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation","0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003989 // acetyl-CoA carboxylase activity // inferred from direct assay /// 0004075 // biotin carboxylase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0009374 // biotin binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation","Fatty_Acid_Synthesis // GenMAPP /// PWY-4381 // HumanCyc /// PWY0-1264 // HumanCyc","IPR000022 // Carboxyl transferase // 5.3E-181 /// IPR000089 // Biotin/lipoyl attachment // 1.4E-17 /// IPR005479 // Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain // 3.2E-52 /// IPR005481 // Carbamoyl-phosphate synthase, large subunit, N-terminal // 4.9E-31 /// IPR005482 // Biotin carboxylase, C-terminal // 2.2E-25 /// IPR013537 // Acetyl-CoA carboxylase, central domain // 7.8E-251"