DB ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count KEGG hsa05150 Staphylococcus aureus infection 25/230 68/7840 1.14537575092225e-21 2.46255786448284e-19 1.84465778832741e-19 FPR3/FCGR3A/ITGAM/HLA-DRB1/HLA-DMA/FCGR2A/FCGR2C/HLA-DQB1/HLA-DPA1/SELPLG/C3AR1/ITGB2/C1QA/HLA-DRA/HLA-DQA1/ITGAL/FPR1/HLA-DPB1/C1QC/HLA-DRB5/C5AR1/HLA-DMB/HLA-DOA/HLA-DQA2/C1QB 25 KEGG hsa04640 Hematopoietic cell lineage 28/230 97/7840 7.41503012894465e-21 7.9711573886155e-19 5.97105057751859e-19 FLT3LG/CD3D/ITGAM/HLA-DRB1/HLA-DMA/CD7/HLA-DQB1/HLA-DPA1/CD2/CD8A/CSF1R/CD38/CD14/CD3E/CSF1/HLA-DRA/HLA-DQA1/CD3G/IL7R/CD4/HLA-DPB1/HLA-DRB5/CD37/IL2RA/CD5/HLA-DMB/HLA-DOA/HLA-DQA2 28 KEGG hsa04514 Cell adhesion molecules (CAMs) 32/230 144/7840 6.50124032110835e-20 4.65922223012765e-18 3.49013954080554e-18 ITGAM/HLA-DRB1/HLA-DMA/CTLA4/PTPRC/HLA-DQB1/HLA-DPA1/CD2/PDCD1/CD8A/SIGLEC1/SELPLG/PDCD1LG2/ITGB7/SPN/ITGB2/HLA-DRA/HLA-E/HLA-DQA1/ITGAL/CD4/CD40/HLA-DPB1/TIGIT/CD274/HLA-DRB5/SELL/CD86/HLA-DMB/HLA-DOA/HLA-DQA2/CD6 32 KEGG hsa05323 Rheumatoid arthritis 25/230 91/7840 3.84067303897363e-18 2.06436175844833e-16 1.54637624990254e-16 TLR2/HLA-DRB1/HLA-DMA/CTLA4/HLA-DQB1/HLA-DPA1/CCL3L1/CCL3L3/ITGB2/CSF1/HLA-DRA/HLA-DQA1/TLR4/ITGAL/CCL3/HLA-DPB1/CCL5/HLA-DRB5/IL15/TNFSF13B/CD86/HLA-DMB/HLA-DOA/HLA-DQA2/ACP5 25 KEGG hsa04062 Chemokine signaling pathway 34/230 190/7840 5.80836981414116e-18 2.4975990200807e-16 1.87090648750231e-16 WAS/RAC2/CXCL9/CCL4L2/CCL4L1/DOCK2/GNGT2/PREX1/FGR/CCL3L1/CCL3L3/CXCR3/VAV1/CXCR6/PIK3CD/HCK/CCR1/PTK2B/GNG2/CXCL11/CXCL10/CCL13/ELMO1/CCR7/CCL3/PIK3R5/JAK3/XCL2/CCL5/CCR5/PLCB2/CCL4/CXCR4/CCL18 34 KEGG hsa04658 Th1 and Th2 cell differentiation 24/230 92/7840 6.95095223169454e-17 2.49075788302388e-15 1.86578191482327e-15 ZAP70/CD3D/HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DPA1/CD247/STAT4/IL2RB/CD3E/HLA-DRA/HLA-DQA1/CD3G/LCK/CD4/JAK3/IL12RB1/HLA-DPB1/HLA-DRB5/IL2RA/IL2RG/HLA-DMB/HLA-DOA/HLA-DQA2 24 KEGG hsa04672 Intestinal immune network for IgA production 18/230 49/7840 6.88126670462316e-16 2.11353191641997e-14 1.58320873053736e-14 HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DPA1/ITGB7/HLA-DRA/HLA-DQA1/CD40/HLA-DPB1/HLA-DRB5/IL15/TNFSF13B/CD86/CXCR4/HLA-DMB/HLA-DOA/HLA-DQA2/IL15RA 18 KEGG hsa05140 Leishmaniasis 21/230 74/7840 1.00638653668605e-15 2.70466381734375e-14 2.02601500148639e-14 TLR2/FCGR3A/ITGAM/HLA-DRB1/HLA-DMA/FCGR2A/FCGR2C/HLA-DQB1/NCF4/HLA-DPA1/PTPN6/CYBB/ITGB2/HLA-DRA/HLA-DQA1/TLR4/HLA-DPB1/HLA-DRB5/HLA-DMB/HLA-DOA/HLA-DQA2 21 KEGG hsa05330 Allograft rejection 16/230 38/7840 2.24525475155632e-15 5.36366412871786e-14 4.01782429225867e-14 HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DPA1/PRF1/HLA-DRA/HLA-E/HLA-DQA1/CD40/HLA-DPB1/HLA-DRB5/GZMB/CD86/HLA-DMB/HLA-DOA/HLA-DQA2 16 KEGG hsa04659 Th17 cell differentiation 24/230 107/7840 2.92662645698854e-15 6.29224688252536e-14 4.71340892546576e-14 ZAP70/CD3D/HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DPA1/CD247/FOXP3/IL2RB/CD3E/HLA-DRA/HLA-DQA1/CD3G/LCK/CD4/JAK3/IL12RB1/HLA-DPB1/HLA-DRB5/IL2RA/IL2RG/HLA-DMB/HLA-DOA/HLA-DQA2 24 KEGG hsa05416 Viral myocarditis 18/230 59/7840 2.97187489197216e-14 5.80866456158194e-13 4.35116610977741e-13 RAC2/HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DPA1/ITGB2/PRF1/HLA-DRA/HLA-E/HLA-DQA1/ITGAL/CD40/HLA-DPB1/HLA-DRB5/CD86/HLA-DMB/HLA-DOA/HLA-DQA2 18 KEGG hsa04612 Antigen processing and presentation 20/230 77/7840 3.27360265712276e-14 5.86520476067828e-13 4.39351935561212e-13 CD74/HLA-DRB1/HLA-DMA/HLA-DQB1/PSME2/HLA-DPA1/CTSS/CD8A/HLA-DRA/HLA-E/HLA-DQA1/CD4/HLA-DPB1/LGMN/HLA-DRB5/HLA-DMB/HLA-DOA/PSME1/IFI30/HLA-DQA2 20 KEGG hsa05320 Autoimmune thyroid disease 17/230 53/7840 6.19619704561736e-14 1.02475566523672e-12 7.67626030752597e-13 HLA-DRB1/HLA-DMA/CTLA4/HLA-DQB1/HLA-DPA1/PRF1/HLA-DRA/HLA-E/HLA-DQA1/CD40/HLA-DPB1/HLA-DRB5/GZMB/CD86/HLA-DMB/HLA-DOA/HLA-DQA2 17 KEGG hsa04060 Cytokine-cytokine receptor interaction 36/230 294/7840 1.3932693309089e-13 2.13966361532438e-12 1.60278351600798e-12 IL10RA/CXCL9/CCL4L2/CCL4L1/TNFRSF1B/CCL3L1/CCL3L3/CXCR3/CSF1R/CXCR6/IL2RB/CCR1/CXCL11/CSF1/CD27/CXCL10/CCL13/IL7R/CD4/CCR7/IL16/CCL3/TNFRSF4/CD40/IL12RB1/XCL2/CCL5/CCR5/IL2RA/IL15/CCL4/TNFSF13B/IL2RG/CXCR4/CCL18/IL15RA 36 KEGG hsa04145 Phagosome 26/230 152/7840 1.85855636536419e-13 2.66393079035533e-12 1.99550262386471e-12 TLR2/FCGR3A/ITGAM/HLA-DRB1/HLA-DMA/FCGR2A/FCGR2C/HLA-DQB1/NCF4/MSR1/HLA-DPA1/CTSS/CYBB/CD14/ITGB2/HLA-DRA/MRC1/HLA-E/HLA-DQA1/TLR4/CORO1A/HLA-DPB1/HLA-DRB5/HLA-DMB/HLA-DOA/HLA-DQA2 26 KEGG hsa05332 Graft-versus-host disease 15/230 41/7840 2.09902216626462e-13 2.82056103591808e-12 2.11283152262162e-12 HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DPA1/PRF1/HLA-DRA/HLA-E/HLA-DQA1/HLA-DPB1/HLA-DRB5/GZMB/CD86/HLA-DMB/HLA-DOA/HLA-DQA2 15 KEGG hsa04940 Type I diabetes mellitus 15/230 43/7840 4.759251129792e-13 6.01905289944282e-12 4.508764228224e-12 HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DPA1/PRF1/HLA-DRA/HLA-E/HLA-DQA1/HLA-DPB1/HLA-DRB5/GZMB/CD86/HLA-DMB/HLA-DOA/HLA-DQA2 15 KEGG hsa05310 Asthma 13/230 31/7840 1.09950812669798e-12 1.31330137355592e-11 9.83770429150822e-12 HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DPA1/HLA-DRA/HLA-DQA1/FCER1G/CD40/HLA-DPB1/HLA-DRB5/HLA-DMB/HLA-DOA/HLA-DQA2 13 KEGG hsa05152 Tuberculosis 27/230 179/7840 1.43400206851403e-12 1.62268655121324e-11 1.21552529907283e-11 IL10RA/TLR2/CD74/FCGR3A/ITGAM/HLA-DRB1/HLA-DMA/FCGR2A/FCGR2C/HLA-DQB1/HLA-DPA1/CTSS/ITGAX/CD14/ITGB2/HLA-DRA/MRC1/HLA-DQA1/TLR4/FCER1G/CORO1A/LSP1/HLA-DPB1/HLA-DRB5/HLA-DMB/HLA-DOA/HLA-DQA2 27 KEGG hsa05321 Inflammatory bowel disease (IBD) 17/230 65/7840 2.619362226492e-12 2.8158143934789e-11 2.10927589817514e-11 TLR2/HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DPA1/STAT4/FOXP3/HLA-DRA/HLA-DQA1/TLR4/IL12RB1/HLA-DPB1/HLA-DRB5/IL2RG/HLA-DMB/HLA-DOA/HLA-DQA2 17 KEGG hsa05166 Human T-cell leukemia virus 1 infection 29/230 219/7840 5.80564755749947e-12 5.94387726124945e-11 4.45245151026275e-11 SPI1/CD3D/HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DPA1/PIK3CD/IL2RB/CD3E/ITGB2/HLA-DRA/HLA-E/HLA-DQA1/CD3G/LCK/ITGAL/CD4/ETS1/JAK3/CD40/HLA-DPB1/HLA-DRB5/IL2RA/IL15/IL2RG/HLA-DMB/HLA-DOA/HLA-DQA2/IL15RA 29 KEGG hsa04380 Osteoclast differentiation 22/230 128/7840 1.35044251267606e-11 1.31975063738797e-10 9.88601456648024e-11 SPI1/LILRA5/LILRB1/FCGR3A/LCP2/FCGR2A/FCGR2C/LILRB2/SIRPG/NCF4/OSCAR/CSF1R/PIK3CD/BTK/CSF1/TYROBP/LCK/SOCS1/LILRB4/PLCG2/ACP5/TREM2 22 KEGG hsa05340 Primary immunodeficiency 12/230 37/7840 2.95796253180243e-10 2.76505193190227e-09 2.0712506515596e-09 ZAP70/CD3D/PTPRC/CD8A/CD3E/BTK/IL7R/LCK/CD4/JAK3/CD40/IL2RG 12 KEGG hsa05145 Toxoplasmosis 19/230 113/7840 5.28465879349516e-10 4.73417350250608e-09 3.54628419037175e-09 IL10RA/TLR2/HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DPA1/HLA-DRA/HLA-DQA1/TLR4/SOCS1/PIK3R5/CD40/HLA-DPB1/CCR5/HLA-DRB5/LY96/HLA-DMB/HLA-DOA/HLA-DQA2 19 KEGG hsa04650 Natural killer cell mediated cytotoxicity 20/230 131/7840 1.07679284238752e-09 9.26041844453266e-09 6.93681283727538e-09 RAC2/ZAP70/FCGR3A/HCST/LCP2/CD48/CD247/PTPN6/VAV1/PIK3CD/ITGB2/PTK2B/PRF1/HLA-E/TYROBP/LCK/ITGAL/FCER1G/GZMB/PLCG2 20 KEGG hsa05169 Epstein-Barr virus infection 24/230 201/7840 3.74060728262704e-09 3.09319448371082e-08 2.31705633296331e-08 TLR2/CD3D/HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DPA1/CD247/PIK3CD/CD3E/BTK/HLA-DRA/HLA-E/HLA-DQA1/CD3G/CXCL10/ITGAL/JAK3/CD40/HLA-DPB1/HLA-DRB5/HLA-DMB/HLA-DOA/PLCG2/HLA-DQA2 24 KEGG hsa04620 Toll-like receptor signaling pathway 17/230 104/7840 6.95972663967824e-09 5.54200454641045e-08 4.15141589033439e-08 CXCL9/CCL4L2/CCL4L1/TLR2/CCL3L1/CCL3L3/PIK3CD/CD14/CXCL11/CXCL10/TLR4/CCL3/CD40/CCL5/CCL4/LY96/CD86 17 KEGG hsa04660 T cell receptor signaling pathway 16/230 101/7840 3.11676153586207e-08 2.39322760789409e-07 1.79272374055225e-07 ZAP70/CD3D/LCP2/CTLA4/PTPRC/CD247/PDCD1/PTPN6/VAV1/CD8A/PIK3CD/CD3E/RASGRP1/CD3G/LCK/CD4 16 KEGG hsa05322 Systemic lupus erythematosus 18/230 133/7840 5.28640663329368e-08 3.91923250399359e-07 2.93582655133914e-07 FCGR3A/HLA-DRB1/HLA-DMA/FCGR2A/HLA-DQB1/HLA-DPA1/C1QA/HLA-DRA/HLA-DQA1/CD40/HLA-DPB1/C1QC/HLA-DRB5/CD86/HLA-DMB/HLA-DOA/HLA-DQA2/C1QB 18 KEGG hsa05142 Chagas disease (American trypanosomiasis) 15/230 103/7840 2.67776536942272e-07 1.91906518141962e-06 1.43753719832167e-06 TLR2/CD3D/CD247/CCL3L1/CCL3L3/PIK3CD/CD3E/C1QA/CD3G/TLR4/CCL3/CCL5/C1QC/PLCB2/C1QB 15 KEGG hsa05170 Human immunodeficiency virus 1 infection 21/230 212/7840 9.16922016395186e-07 6.35929785564403e-06 4.76363560300385e-06 RAC2/APOBEC3C/TLR2/GNGT2/CD3D/TNFRSF1B/CD247/APOBEC3D/PIK3CD/CD3E/PTK2B/GNG2/HLA-E/CD3G/APOBEC3G/TLR4/CD4/APOBEC3H/CCR5/CXCR4/PLCG2 21 KEGG hsa05133 Pertussis 12/230 76/7840 1.7982738474581e-06 1.20821524126091e-05 9.05052298227266e-06 IRF8/SERPING1/ITGAM/CD14/ITGB2/C1QA/TLR4/CASP1/C1QC/LY96/C1QB/IRF1 12 KEGG hsa04064 NF-kappa B signaling pathway 13/230 95/7840 3.51388906011715e-06 2.28935196340966e-05 1.7149123642677e-05 ZAP70/CCL4L2/CCL4L1/CD14/BTK/CCL13/LCK/TLR4/CD40/CCL4/TNFSF13B/LY96/PLCG2 13 KEGG hsa05132 Salmonella infection 11/230 86/7840 3.83930565843211e-05 0.000238447143987208 0.000178616465263367 WAS/CCL4L2/CCL4L1/CCL3L1/CCL3L3/CD14/TLR4/CASP1/CCL3/CCL4/RHOG 11 KEGG hsa05164 Influenza A 16/230 171/7840 3.88169769281501e-05 0.000238447143987208 0.000178616465263367 HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DPA1/PIK3CD/HLA-DRA/HLA-DQA1/CXCL10/TLR4/CASP1/HLA-DPB1/CCL5/HLA-DRB5/HLA-DMB/HLA-DOA/HLA-DQA2 16 KEGG hsa04666 Fc gamma R-mediated phagocytosis 11/230 91/7840 6.52881671764211e-05 0.000389915442859181 0.000292078642631357 WAS/RAC2/DOCK2/FCGR3A/FCGR2A/PTPRC/VAV1/INPP5D/PIK3CD/HCK/PLCG2 11 KEGG hsa04610 Complement and coagulation cascades 10/230 79/7840 9.48304629580108e-05 0.000551041879350604 0.000412775557114528 SERPING1/ITGAM/ITGAX/C3AR1/ITGB2/C1QA/VSIG4/C1QC/C5AR1/C1QB 10 KEGG hsa05163 Human cytomegalovirus infection 18/230 225/7840 0.000102077856714852 0.000577545768255084 0.000432629143417517 IL10RA/RAC2/CCL4L2/CCL4L1/GNGT2/CCL3L1/CCL3L3/PIK3CD/CCR1/PTK2B/GNG2/HLA-E/CCL3/CCL5/CCR5/PLCB2/CCL4/CXCR4 18 KEGG hsa04664 Fc epsilon RI signaling pathway 9/230 68/7840 0.000150188988547792 0.000827964936866036 0.00062021363691801 RAC2/LCP2/VAV1/INPP5D/PIK3CD/BTK/ALOX5AP/FCER1G/PLCG2 9 KEGG hsa04662 B cell receptor signaling pathway 9/230 71/7840 0.000210294749945874 0.00113033428095907 0.000846713072150492 CD79B/RAC2/PTPN6/VAV1/INPP5D/PIK3CD/CD72/BTK/PLCG2 9 KEGG hsa04611 Platelet activation 12/230 124/7840 0.000266480278964547 0.00139739658481409 0.00104676463880811 FERMT3/LCP2/TBXAS1/FCGR2A/PIK3CD/BTK/RASGRP1/PIK3R5/FCER1G/APBB1IP/PLCB2/PLCG2 12 KEGG hsa04670 Leukocyte transendothelial migration 11/230 112/7840 0.000421746692783546 0.00215894140353482 0.00161722416029781 RAC2/ITGAM/NCF4/VAV1/CYBB/PIK3CD/ITGB2/PTK2B/ITGAL/CXCR4/PLCG2 11 KEGG hsa04630 JAK-STAT signaling pathway 13/230 162/7840 0.000918855264688343 0.00456331384763408 0.00341829629712614 IL10RA/PTPN6/STAT4/PIK3CD/IL2RB/IL7R/SOCS1/JAK3/IL12RB1/IL2RA/IL15/IL2RG/IL15RA 13 KEGG hsa04142 Lysosome 11/230 123/7840 0.000933887485097207 0.00456331384763408 0.00341829629712614 PSAP/CTSW/CTSS/CTSZ/MAN2B1/LIPA/LAPTM5/LGMN/ACP2/SLC11A1/ACP5 11 KEGG hsa04621 NOD-like receptor signaling pathway 13/230 178/7840 0.00216468518865752 0.0103423847902526 0.00774729435940587 GBP5/PSTPIP1/GBP2/CARD16/GBP4/GBP1/CYBB/TLR4/CASP1/TRPV2/CCL5/PLCB2/TRPM2 13 KEGG hsa05144 Malaria 6/230 49/7840 0.00290689170283244 0.0135865590458473 0.0101774469229603 KLRB1/TLR2/ITGB2/TLR4/ITGAL/CD40 6 KEGG hsa04810 Regulation of actin cytoskeleton 14/230 214/7840 0.0040787184138888 0.0186579672124701 0.0139763475324745 WAS/RAC2/ITGAM/ITGAE/ARHGEF6/VAV1/ITGAX/PIK3CD/ITGB7/ITGB2/FGD3/ITGAL/NCKAP1L/CXCR4 14 KEGG hsa05134 Legionellosis 6/230 55/7840 0.00520964519115279 0.0233348690853719 0.0174797305755784 TLR2/ITGAM/CD14/ITGB2/TLR4/CASP1 6 KEGG hsa05162 Measles 10/230 132/7840 0.00531898271052391 0.0233383935257682 0.0174823706704653 TLR2/CD3D/PIK3CD/IL2RB/CD3E/CD3G/TLR4/JAK3/IL2RA/IL2RG 10 KEGG hsa04623 Cytosolic DNA-sensing pathway 6/230 63/7840 0.010063522841789 0.0432731482196928 0.0324151367324994 CCL4L2/CCL4L1/CXCL10/CASP1/CCL5/CCL4 6 BP GO:0042110 T cell activation 87/363 467/17381 3.76814028639088e-58 1.1221521772872e-54 8.17091472627916e-55 WAS/RAC2/ZAP70/NLRC3/SIT1/EBI3/LILRB1/DOCK2/CD74/DOCK8/LAG3/PREX1/CD3D/HLA-DRB1/CTLA4/LILRB2/SIRPG/PTPRC/CD7/HAVCR2/HLA-DQB1/BATF/HLA-DPA1/CD2/CD247/PDCD1/PTPN6/VAV1/CD8A/IDO1/PDCD1LG2/PIK3CD/FOXP3/PAG1/HLA-DQB2/SPN/CD3E/AIF1/LCP1/HLA-DRA/BTN3A1/RASGRP1/HLA-E/GPR183/HLA-DQA1/CD3G/RASAL3/CD27/CD300A/TNFAIP8L2/VSIG4/IL7R/LCK/JAML/ITGAL/CD4/CCR7/NCKAP1L/SOCS1/SLAMF6/FCER1G/TNFRSF4/JAK3/CORO1A/IL12RB1/HLA-DPB1/CCL5/APBB1IP/LILRB4/TIGIT/CD274/HLA-DRB5/ZNF683/IL2RA/IL15/CD5/RAB27A/TNFSF13B/CD86/SLA2/HLA-DMB/SLC11A1/HLA-DOA/SASH3/HLA-DQA2/IRF1/CD6 87 BP GO:0051249 regulation of lymphocyte activation 82/363 455/17381 1.7941436168525e-53 2.67147984549337e-50 1.94522939511376e-50 RAC2/FLT3LG/ZAP70/NFAM1/SIT1/EBI3/LILRB1/CD74/DOCK8/LAG3/CD3D/HLA-DRB1/CTLA4/LILRB2/SIRPG/PTPRC/HAVCR2/HLA-DQB1/MNDA/HLA-DPA1/CD2/CD247/PDCD1/LST1/PTPN6/VAV1/IDO1/PDCD1LG2/INPP5D/FOXP3/PAG1/HLA-DQB2/CD38/SPN/CD3E/AIF1/TBC1D10C/BTK/HLA-DRA/RASGRP1/HLA-E/GPR183/HLA-DQA1/CD3G/SAMSN1/RASAL3/CD27/CD300A/TNFAIP8L2/VSIG4/IL7R/LCK/TLR4/CD4/CCR7/NCKAP1L/SOCS1/TNFRSF4/JAK3/CD40/CORO1A/IL12RB1/HLA-DPB1/CCL5/LILRB4/TIGIT/CD274/HLA-DRB5/ZNF683/IL2RA/IKZF3/IL15/CD5/TNFSF13B/CD86/SLA2/HLA-DMB/HLA-DOA/SASH3/HLA-DQA2/IRF1/CD6 82 BP GO:0007159 leukocyte cell-cell adhesion 75/363 374/17381 2.66279330241169e-52 2.64326615152734e-49 1.92468568525196e-49 RAC2/ZAP70/SIT1/EBI3/LILRB1/CD74/DOCK8/LAG3/FERMT3/CD3D/HLA-DRB1/CTLA4/STK10/LILRB2/SIRPG/PTPRC/HAVCR2/HLA-DQB1/HLA-DPA1/CD2/CD247/PDCD1/PTPN6/SEMA4D/VAV1/SELPLG/IDO1/PDCD1LG2/FOXP3/PAG1/ITGB7/HLA-DQB2/SPN/CD3E/AIF1/ITGB2/HLA-DRA/RASGRP1/HLA-E/HLA-DQA1/CD3G/RASAL3/CD27/CD300A/TNFAIP8L2/VSIG4/IL7R/LCK/ITGAL/CD4/CCR7/NCKAP1L/SOCS1/ETS1/JAK3/CORO1A/IL12RB1/HLA-DPB1/CCL5/LILRB4/TIGIT/CD274/HLA-DRB5/ZNF683/IL2RA/IL15/CD5/TNFSF13B/CD86/HLA-DMB/HLA-DOA/SASH3/HLA-DQA2/IRF1/CD6 75 BP GO:0050863 regulation of T cell activation 67/363 322/17381 1.04515565875352e-47 7.78118387941997e-45 5.66584383429541e-45 RAC2/ZAP70/SIT1/EBI3/LILRB1/CD74/DOCK8/LAG3/CD3D/HLA-DRB1/CTLA4/LILRB2/SIRPG/PTPRC/HAVCR2/HLA-DQB1/HLA-DPA1/CD2/CD247/PDCD1/PTPN6/VAV1/IDO1/PDCD1LG2/FOXP3/PAG1/HLA-DQB2/SPN/CD3E/AIF1/HLA-DRA/RASGRP1/HLA-E/HLA-DQA1/CD3G/RASAL3/CD27/CD300A/TNFAIP8L2/VSIG4/IL7R/LCK/CD4/CCR7/NCKAP1L/SOCS1/JAK3/CORO1A/IL12RB1/HLA-DPB1/CCL5/LILRB4/TIGIT/CD274/HLA-DRB5/ZNF683/IL2RA/IL15/CD5/TNFSF13B/CD86/HLA-DMB/HLA-DOA/SASH3/HLA-DQA2/IRF1/CD6 67 BP GO:1903037 regulation of leukocyte cell-cell adhesion 68/363 343/17381 5.84572608547223e-47 3.48171445650726e-44 2.53519910233112e-44 RAC2/ZAP70/SIT1/EBI3/LILRB1/CD74/DOCK8/LAG3/CD3D/HLA-DRB1/CTLA4/LILRB2/SIRPG/PTPRC/HAVCR2/HLA-DQB1/HLA-DPA1/CD2/CD247/PDCD1/PTPN6/VAV1/IDO1/PDCD1LG2/FOXP3/PAG1/HLA-DQB2/SPN/CD3E/AIF1/HLA-DRA/RASGRP1/HLA-E/HLA-DQA1/CD3G/RASAL3/CD27/CD300A/TNFAIP8L2/VSIG4/IL7R/LCK/CD4/CCR7/NCKAP1L/SOCS1/ETS1/JAK3/CORO1A/IL12RB1/HLA-DPB1/CCL5/LILRB4/TIGIT/CD274/HLA-DRB5/ZNF683/IL2RA/IL15/CD5/TNFSF13B/CD86/HLA-DMB/HLA-DOA/SASH3/HLA-DQA2/IRF1/CD6 68 BP GO:0002696 positive regulation of leukocyte activation 67/363 347/17381 1.80400573667398e-45 8.95388180635852e-43 6.51974003078666e-43 FLT3LG/ZAP70/EBI3/LILRB1/CD74/DOCK8/CD3D/ITGAM/HLA-DRB1/CTLA4/LILRB2/SIRPG/PTPRC/HAVCR2/HLA-DQB1/HLA-DPA1/CD2/FGR/CD247/PDCD1/PTPN6/VAV1/PDCD1LG2/INPP5D/FOXP3/HLA-DQB2/CD38/SPN/CD3E/AIF1/ITGB2/BTK/HLA-DRA/RASGRP1/HLA-E/GPR183/HLA-DQA1/CD3G/RASAL3/CD27/IL7R/LCK/TLR4/CD4/CCR7/NCKAP1L/SOCS1/FCER1G/TNFRSF4/JAK3/CD40/CORO1A/IL12RB1/HLA-DPB1/CCL5/LILRB4/CD274/HLA-DRB5/IL2RA/IL15/CD5/TNFSF13B/CD86/HLA-DMB/SASH3/HLA-DQA2/CD6 67 BP GO:0050867 positive regulation of cell activation 67/363 359/17381 1.82659899635764e-44 7.77087401593292e-42 5.65833674059659e-42 FLT3LG/ZAP70/EBI3/LILRB1/CD74/DOCK8/CD3D/ITGAM/HLA-DRB1/CTLA4/LILRB2/SIRPG/PTPRC/HAVCR2/HLA-DQB1/HLA-DPA1/CD2/FGR/CD247/PDCD1/PTPN6/VAV1/PDCD1LG2/INPP5D/FOXP3/HLA-DQB2/CD38/SPN/CD3E/AIF1/ITGB2/BTK/HLA-DRA/RASGRP1/HLA-E/GPR183/HLA-DQA1/CD3G/RASAL3/CD27/IL7R/LCK/TLR4/CD4/CCR7/NCKAP1L/SOCS1/FCER1G/TNFRSF4/JAK3/CD40/CORO1A/IL12RB1/HLA-DPB1/CCL5/LILRB4/CD274/HLA-DRB5/IL2RA/IL15/CD5/TNFSF13B/CD86/HLA-DMB/SASH3/HLA-DQA2/CD6 67 BP GO:0050870 positive regulation of T cell activation 54/363 215/17381 4.85736200648048e-43 1.65073170869354e-40 1.20197494606366e-40 ZAP70/EBI3/LILRB1/CD74/DOCK8/CD3D/HLA-DRB1/CTLA4/LILRB2/SIRPG/PTPRC/HAVCR2/HLA-DQB1/HLA-DPA1/CD247/PDCD1/PTPN6/VAV1/PDCD1LG2/FOXP3/HLA-DQB2/SPN/CD3E/AIF1/HLA-DRA/RASGRP1/HLA-E/HLA-DQA1/CD3G/RASAL3/CD27/IL7R/LCK/CD4/CCR7/NCKAP1L/SOCS1/JAK3/CORO1A/IL12RB1/HLA-DPB1/CCL5/LILRB4/CD274/HLA-DRB5/IL2RA/IL15/CD5/TNFSF13B/CD86/HLA-DMB/SASH3/HLA-DQA2/CD6 54 BP GO:1903039 positive regulation of leukocyte cell-cell adhesion 55/363 226/17381 4.98877950914772e-43 1.65073170869354e-40 1.20197494606366e-40 ZAP70/EBI3/LILRB1/CD74/DOCK8/CD3D/HLA-DRB1/CTLA4/LILRB2/SIRPG/PTPRC/HAVCR2/HLA-DQB1/HLA-DPA1/CD247/PDCD1/PTPN6/VAV1/PDCD1LG2/FOXP3/HLA-DQB2/SPN/CD3E/AIF1/HLA-DRA/RASGRP1/HLA-E/HLA-DQA1/CD3G/RASAL3/CD27/IL7R/LCK/CD4/CCR7/NCKAP1L/SOCS1/ETS1/JAK3/CORO1A/IL12RB1/HLA-DPB1/CCL5/LILRB4/CD274/HLA-DRB5/IL2RA/IL15/CD5/TNFSF13B/CD86/HLA-DMB/SASH3/HLA-DQA2/CD6 55 BP GO:0051251 positive regulation of lymphocyte activation 62/363 315/17381 1.4727875709203e-42 4.38596138620065e-40 3.1936235748377e-40 FLT3LG/ZAP70/EBI3/LILRB1/CD74/DOCK8/CD3D/HLA-DRB1/CTLA4/LILRB2/SIRPG/PTPRC/HAVCR2/HLA-DQB1/HLA-DPA1/CD247/PDCD1/PTPN6/VAV1/PDCD1LG2/INPP5D/FOXP3/HLA-DQB2/CD38/SPN/CD3E/AIF1/BTK/HLA-DRA/RASGRP1/HLA-E/GPR183/HLA-DQA1/CD3G/RASAL3/CD27/IL7R/LCK/TLR4/CD4/CCR7/NCKAP1L/SOCS1/TNFRSF4/JAK3/CD40/CORO1A/IL12RB1/HLA-DPB1/CCL5/LILRB4/CD274/HLA-DRB5/IL2RA/IL15/CD5/TNFSF13B/CD86/HLA-DMB/SASH3/HLA-DQA2/CD6 62 BP GO:0022407 regulation of cell-cell adhesion 69/363 425/17381 1.1958513125418e-41 3.23749564431772e-39 2.35737196539341e-39 RAC2/ZAP70/SIT1/EBI3/LILRB1/CD74/DOCK8/LAG3/FERMT3/CD3D/HLA-DRB1/CTLA4/LILRB2/SIRPG/PTPRC/HAVCR2/HLA-DQB1/HLA-DPA1/CD2/CD247/PDCD1/PTPN6/VAV1/IDO1/PDCD1LG2/FOXP3/PAG1/HLA-DQB2/SPN/CD3E/AIF1/HLA-DRA/RASGRP1/HLA-E/HLA-DQA1/CD3G/RASAL3/CD27/CD300A/TNFAIP8L2/VSIG4/IL7R/LCK/CD4/CCR7/NCKAP1L/SOCS1/ETS1/JAK3/CORO1A/IL12RB1/HLA-DPB1/CCL5/LILRB4/TIGIT/CD274/HLA-DRB5/ZNF683/IL2RA/IL15/CD5/TNFSF13B/CD86/HLA-DMB/HLA-DOA/SASH3/HLA-DQA2/IRF1/CD6 69 BP GO:0022409 positive regulation of cell-cell adhesion 55/363 259/17381 1.34379707319453e-39 3.33485640331109e-37 2.42826488664976e-37 ZAP70/EBI3/LILRB1/CD74/DOCK8/CD3D/HLA-DRB1/CTLA4/LILRB2/SIRPG/PTPRC/HAVCR2/HLA-DQB1/HLA-DPA1/CD247/PDCD1/PTPN6/VAV1/PDCD1LG2/FOXP3/HLA-DQB2/SPN/CD3E/AIF1/HLA-DRA/RASGRP1/HLA-E/HLA-DQA1/CD3G/RASAL3/CD27/IL7R/LCK/CD4/CCR7/NCKAP1L/SOCS1/ETS1/JAK3/CORO1A/IL12RB1/HLA-DPB1/CCL5/LILRB4/CD274/HLA-DRB5/IL2RA/IL15/CD5/TNFSF13B/CD86/HLA-DMB/SASH3/HLA-DQA2/CD6 55 BP GO:0032943 mononuclear cell proliferation 54/363 270/17381 1.98141476480691e-37 4.53896397661152e-35 3.30503191538643e-35 RAC2/ZAP70/EBI3/LILRB1/DOCK2/CD74/DOCK8/CTLA4/LILRB2/PTPRC/HAVCR2/MNDA/HLA-DPA1/LST1/PTPN6/IDO1/PDCD1LG2/INPP5D/FOXP3/CD38/SPN/CD3E/AIF1/BTK/CSF1/BTN3A1/HLA-E/GPR183/RASAL3/CD300A/VSIG4/IL7R/TLR4/CD4/NCKAP1L/SLAMF6/TNFRSF4/JAK3/CD40/CORO1A/IL12RB1/HLA-DPB1/CCL5/CD274/IL2RA/IKZF3/IL15/TNFSF13B/CD86/HLA-DMB/SLC11A1/SASH3/IRF1/CD6 54 BP GO:0070661 leukocyte proliferation 55/363 286/17381 3.63304570742414e-37 7.72800722622078e-35 5.62712342653664e-35 RAC2/FLT3LG/ZAP70/EBI3/LILRB1/DOCK2/CD74/DOCK8/CTLA4/LILRB2/PTPRC/HAVCR2/MNDA/HLA-DPA1/LST1/PTPN6/IDO1/PDCD1LG2/INPP5D/FOXP3/CD38/SPN/CD3E/AIF1/BTK/CSF1/BTN3A1/HLA-E/GPR183/RASAL3/CD300A/VSIG4/IL7R/TLR4/CD4/NCKAP1L/SLAMF6/TNFRSF4/JAK3/CD40/CORO1A/IL12RB1/HLA-DPB1/CCL5/CD274/IL2RA/IKZF3/IL15/TNFSF13B/CD86/HLA-DMB/SLC11A1/SASH3/IRF1/CD6 55 BP GO:0070663 regulation of leukocyte proliferation 49/363 217/17381 1.16233605188351e-36 2.3076245083394e-34 1.68028931009125e-34 RAC2/FLT3LG/ZAP70/EBI3/LILRB1/CD74/CTLA4/LILRB2/PTPRC/HAVCR2/MNDA/HLA-DPA1/LST1/PTPN6/IDO1/PDCD1LG2/INPP5D/FOXP3/CD38/SPN/CD3E/AIF1/BTK/CSF1/HLA-E/GPR183/RASAL3/CD300A/VSIG4/TLR4/CD4/NCKAP1L/TNFRSF4/JAK3/CD40/CORO1A/IL12RB1/HLA-DPB1/CCL5/CD274/IL2RA/IKZF3/IL15/TNFSF13B/CD86/HLA-DMB/SASH3/IRF1/CD6 49 BP GO:0032944 regulation of mononuclear cell proliferation 48/363 207/17381 1.67200017170974e-36 3.11201031959476e-34 2.26600023271189e-34 RAC2/ZAP70/EBI3/LILRB1/CD74/CTLA4/LILRB2/PTPRC/HAVCR2/MNDA/HLA-DPA1/LST1/PTPN6/IDO1/PDCD1LG2/INPP5D/FOXP3/CD38/SPN/CD3E/AIF1/BTK/CSF1/HLA-E/GPR183/RASAL3/CD300A/VSIG4/TLR4/CD4/NCKAP1L/TNFRSF4/JAK3/CD40/CORO1A/IL12RB1/HLA-DPB1/CCL5/CD274/IL2RA/IKZF3/IL15/TNFSF13B/CD86/HLA-DMB/SASH3/IRF1/CD6 48 BP GO:0046651 lymphocyte proliferation 53/363 268/17381 1.79125652174403e-36 3.13785995397278e-34 2.28482256024316e-34 RAC2/ZAP70/EBI3/LILRB1/DOCK2/CD74/DOCK8/CTLA4/LILRB2/PTPRC/HAVCR2/MNDA/HLA-DPA1/LST1/PTPN6/IDO1/PDCD1LG2/INPP5D/FOXP3/CD38/SPN/CD3E/AIF1/BTK/BTN3A1/HLA-E/GPR183/RASAL3/CD300A/VSIG4/IL7R/TLR4/CD4/NCKAP1L/SLAMF6/TNFRSF4/JAK3/CD40/CORO1A/IL12RB1/HLA-DPB1/CCL5/CD274/IL2RA/IKZF3/IL15/TNFSF13B/CD86/HLA-DMB/SLC11A1/SASH3/IRF1/CD6 53 BP GO:0050670 regulation of lymphocyte proliferation 47/363 206/17381 2.11051618989518e-35 3.49173178528213e-33 2.54249318782694e-33 RAC2/ZAP70/EBI3/LILRB1/CD74/CTLA4/LILRB2/PTPRC/HAVCR2/MNDA/HLA-DPA1/LST1/PTPN6/IDO1/PDCD1LG2/INPP5D/FOXP3/CD38/SPN/CD3E/AIF1/BTK/HLA-E/GPR183/RASAL3/CD300A/VSIG4/TLR4/CD4/NCKAP1L/TNFRSF4/JAK3/CD40/CORO1A/IL12RB1/HLA-DPB1/CCL5/CD274/IL2RA/IKZF3/IL15/TNFSF13B/CD86/HLA-DMB/SASH3/IRF1/CD6 47 BP GO:0002768 immune response-regulating cell surface receptor signaling pathway 64/363 458/17381 1.49171281240013e-34 2.33806355543557e-32 1.70245340362564e-32 CD79B/WAS/FPR3/ZAP70/FYB1/NFAM1/LILRB1/CD3D/FCGR3A/LCP2/HLA-DRB1/FCGR2A/CTLA4/WIPF1/LILRB2/PSMB10/PTPRC/HLA-DQB1/PSME2/GBP1/MNDA/HLA-DPA1/FGR/CD247/PTPN6/THEMIS2/VAV1/LAT2/GCSAM/INPP5D/PIK3CD/FOXP3/HCK/PAG1/C3AR1/HLA-DQB2/CD38/LPXN/CD3E/BTK/CLEC4A/HLA-DRA/BTN3A1/HLA-DQA1/CD3G/MYO1G/CD300A/ELMO1/LCK/CD4/CCR7/FPR1/NCKAP1L/FCER1G/CD40/HLA-DPB1/LILRB4/HLA-DRB5/C5AR1/SLA2/PSMB9/PSME1/PLCG2/HLA-DQA2 64 BP GO:0002521 leukocyte differentiation 65/363 479/17381 2.58027383824809e-34 3.84202774515141e-32 2.79756005620582e-32 CD79B/DOCK10/SPI1/FLT3LG/ZAP70/NFAM1/LILRB1/DOCK2/TLR2/CD74/PREX1/POU2F2/CD3D/CTLA4/EVI2B/LILRB2/PTPRC/BATF/CD2/PTPN6/VAV1/CD8A/CSF1R/INPP5D/PIK3CD/FOXP3/SPN/CD3E/BTK/CCR1/PTK2B/CSF1/RASGRP1/GPR183/CD27/TYROBP/IL7R/LCK/TLR4/CD4/CCR7/NCKAP1L/CCL3/SOCS1/SLAMF6/FCER1G/JAK3/IL12RB1/LYL1/MFNG/C1QC/LILRB4/IKZF1/ZNF683/IL2RA/TRPM2/IKZF3/SNX10/IL15/CD86/HLA-DOA/SASH3/PLCG2/IRF1/TREM2 65 BP GO:0050900 leukocyte migration 64/363 471/17381 8.14460661577067e-34 1.15498278579834e-31 8.40996973859026e-32 MCOLN2/RAC2/FPR3/CXCL9/ZAP70/CCL4L1/CD74/DOCK8/PREX1/ITGAM/STK10/CD48/SIRPG/CD2/CCL3L1/CCL3L3/CXCR3/PTPN6/VAV1/GCSAM/SELPLG/ITGAX/INPP5D/PIK3CD/HCK/C3AR1/ITGB7/SPN/AIF1/GPSM3/ITGB2/CCR1/PTK2B/CXCL11/CSF1/SLC7A7/GPR183/MYO1G/CD300A/CXCL10/CCL13/LCK/JAML/ITGAL/CCR7/IL16/FPR1/NCKAP1L/CCL3/FCER1G/CORO1A/MPP1/PLA2G7/XCL2/CCL5/CCR5/CMKLR1/TRPM2/SELL/CCL4/C5AR1/DOK2/CXCR4/CCL18 64 BP GO:0002429 immune response-activating cell surface receptor signaling pathway 61/363 426/17381 1.55383045026517e-33 2.0354181660637e-31 1.48208314378821e-31 CD79B/WAS/FPR3/ZAP70/FYB1/NFAM1/CD3D/FCGR3A/LCP2/HLA-DRB1/FCGR2A/CTLA4/WIPF1/PSMB10/PTPRC/HLA-DQB1/PSME2/GBP1/MNDA/HLA-DPA1/FGR/CD247/PTPN6/THEMIS2/VAV1/LAT2/GCSAM/INPP5D/PIK3CD/FOXP3/HCK/PAG1/C3AR1/HLA-DQB2/CD38/LPXN/CD3E/BTK/CLEC4A/HLA-DRA/BTN3A1/HLA-DQA1/CD3G/MYO1G/CD300A/ELMO1/LCK/CD4/CCR7/FPR1/NCKAP1L/FCER1G/HLA-DPB1/LILRB4/HLA-DRB5/C5AR1/SLA2/PSMB9/PSME1/PLCG2/HLA-DQA2 61 BP GO:0045785 positive regulation of cell adhesion 59/363 394/17381 1.57201537338701e-33 2.0354181660637e-31 1.48208314378821e-31 ZAP70/EBI3/LILRB1/CD74/DOCK8/PREX1/CD3D/HLA-DRB1/CTLA4/LILRB2/SIRPG/PTPRC/HAVCR2/HLA-DQB1/HLA-DPA1/CD247/PDCD1/PTPN6/VAV1/PDCD1LG2/FOXP3/HLA-DQB2/SPN/CD3E/AIF1/PTK2B/CSF1/HLA-DRA/RASGRP1/HLA-E/HLA-DQA1/CD3G/RASAL3/CD27/IL7R/LCK/CD4/CCR7/NCKAP1L/SOCS1/ETS1/JAK3/CORO1A/IL12RB1/HLA-DPB1/CCL5/APBB1IP/LILRB4/CD274/HLA-DRB5/IL2RA/IL15/CD5/TNFSF13B/CD86/HLA-DMB/SASH3/HLA-DQA2/CD6 59 BP GO:0030098 lymphocyte differentiation 52/363 328/17381 8.24351776525251e-31 1.02288316270508e-28 7.44809061246499e-29 CD79B/DOCK10/SPI1/FLT3LG/ZAP70/NFAM1/DOCK2/CD74/PREX1/POU2F2/CD3D/CTLA4/LILRB2/PTPRC/BATF/CD2/PTPN6/VAV1/CD8A/INPP5D/PIK3CD/FOXP3/SPN/CD3E/BTK/PTK2B/RASGRP1/GPR183/CD27/IL7R/LCK/CD4/CCR7/NCKAP1L/SOCS1/SLAMF6/FCER1G/JAK3/IL12RB1/LYL1/MFNG/LILRB4/IKZF1/ZNF683/IL2RA/IKZF3/IL15/CD86/HLA-DOA/SASH3/PLCG2/IRF1 52 BP GO:0050851 antigen receptor-mediated signaling pathway 47/363 257/17381 9.15728251127712e-31 1.09081549274333e-28 7.94273767293931e-29 CD79B/WAS/ZAP70/FYB1/NFAM1/CD3D/LCP2/HLA-DRB1/CTLA4/PSMB10/PTPRC/HLA-DQB1/PSME2/GBP1/MNDA/HLA-DPA1/CD247/PTPN6/THEMIS2/LAT2/GCSAM/INPP5D/PIK3CD/FOXP3/PAG1/HLA-DQB2/CD38/LPXN/CD3E/BTK/HLA-DRA/BTN3A1/HLA-DQA1/CD3G/CD300A/LCK/CD4/CCR7/NCKAP1L/HLA-DPB1/LILRB4/HLA-DRB5/SLA2/PSMB9/PSME1/PLCG2/HLA-DQA2 47 BP GO:0042098 T cell proliferation 40/363 181/17381 1.22423610859678e-29 1.40222120438508e-27 1.0210228274127e-27 RAC2/ZAP70/EBI3/LILRB1/DOCK2/DOCK8/CTLA4/LILRB2/PTPRC/HAVCR2/HLA-DPA1/PTPN6/IDO1/PDCD1LG2/FOXP3/SPN/CD3E/AIF1/BTN3A1/HLA-E/RASAL3/VSIG4/CD4/NCKAP1L/TNFRSF4/JAK3/CORO1A/IL12RB1/HLA-DPB1/CCL5/CD274/IL2RA/IL15/TNFSF13B/CD86/HLA-DMB/SLC11A1/SASH3/IRF1/CD6 40 BP GO:0070665 positive regulation of leukocyte proliferation 36/363 144/17381 8.54035940504467e-29 9.41970011415668e-27 6.85892412256999e-27 FLT3LG/ZAP70/EBI3/CD74/LILRB2/PTPRC/HAVCR2/HLA-DPA1/PDCD1LG2/FOXP3/CD38/SPN/CD3E/AIF1/CSF1/HLA-E/GPR183/RASAL3/TLR4/CD4/NCKAP1L/TNFRSF4/JAK3/CD40/CORO1A/IL12RB1/HLA-DPB1/CCL5/CD274/IL2RA/IL15/TNFSF13B/CD86/HLA-DMB/SASH3/CD6 36 BP GO:0032946 positive regulation of mononuclear cell proliferation 35/363 137/17381 2.25265601390123e-28 2.39586057478495e-26 1.74453811602877e-26 ZAP70/EBI3/CD74/LILRB2/PTPRC/HAVCR2/HLA-DPA1/PDCD1LG2/FOXP3/CD38/SPN/CD3E/AIF1/CSF1/HLA-E/GPR183/RASAL3/TLR4/CD4/NCKAP1L/TNFRSF4/JAK3/CD40/CORO1A/IL12RB1/HLA-DPB1/CCL5/CD274/IL2RA/IL15/TNFSF13B/CD86/HLA-DMB/SASH3/CD6 35 BP GO:0050671 positive regulation of lymphocyte proliferation 34/363 136/17381 3.02207883989753e-27 3.10336233972926e-25 2.25970323418836e-25 ZAP70/EBI3/CD74/LILRB2/PTPRC/HAVCR2/HLA-DPA1/PDCD1LG2/FOXP3/CD38/SPN/CD3E/AIF1/HLA-E/GPR183/RASAL3/TLR4/CD4/NCKAP1L/TNFRSF4/JAK3/CD40/CORO1A/IL12RB1/HLA-DPB1/CCL5/CD274/IL2RA/IL15/TNFSF13B/CD86/HLA-DMB/SASH3/CD6 34 BP GO:0034341 response to interferon-gamma 36/363 165/17381 1.50361076026086e-26 1.49258428135228e-24 1.08682040917101e-24 GBP5/IRF8/GBP2/CCL4L1/HLA-DRB1/HLA-DQB1/GBP1/NUB1/HLA-DPA1/CCL3L1/CCL3L3/HCK/HLA-DQB2/AIF1/HLA-DRA/MRC1/HLA-E/HLA-DQA1/CCL13/CASP1/CCL3/SOCS1/CD40/IL12RB1/XCL2/HLA-DPB1/CCL5/NR1H3/HLA-DRB5/CCL4/CD86/CCL18/SLC11A1/IFI30/HLA-DQA2/IRF1 36 BP GO:0030595 leukocyte chemotaxis 39/363 203/17381 1.75671988798846e-26 1.6875844601386e-24 1.22880915764219e-24 RAC2/CXCL9/CCL4L1/CD74/PREX1/CCL3L1/CCL3L3/CXCR3/VAV1/PIK3CD/C3AR1/AIF1/GPSM3/ITGB2/CCR1/PTK2B/CXCL11/CSF1/GPR183/CXCL10/CCL13/JAML/CCR7/IL16/NCKAP1L/CCL3/FCER1G/CORO1A/MPP1/PLA2G7/XCL2/CCL5/CCR5/CMKLR1/TRPM2/CCL4/C5AR1/CXCR4/CCL18 39 BP GO:0042129 regulation of T cell proliferation 35/363 155/17381 2.21148560187313e-26 2.05806378824318e-24 1.49857248021666e-24 RAC2/ZAP70/EBI3/LILRB1/CTLA4/LILRB2/PTPRC/HAVCR2/HLA-DPA1/PTPN6/IDO1/PDCD1LG2/FOXP3/SPN/CD3E/AIF1/HLA-E/RASAL3/VSIG4/CD4/NCKAP1L/JAK3/CORO1A/IL12RB1/HLA-DPB1/CCL5/CD274/IL2RA/IL15/TNFSF13B/CD86/HLA-DMB/SASH3/IRF1/CD6 35 BP GO:0002683 negative regulation of immune system process 52/363 412/17381 6.34570514238749e-26 5.72651815576665e-24 4.16974564380167e-24 GPR171/CD96/NLRC3/LILRB1/CD74/LAG3/SERPING1/TRAFD1/CTLA4/LILRB2/PTPRC/CD300LF/HAVCR2/MILR1/GBP1/MNDA/PDCD1/LST1/PTPN6/GCSAM/IDO1/PDCD1LG2/INPP5D/FOXP3/PAG1/SPN/LPXN/CD14/TBC1D10C/BTK/PTK2B/HLA-E/SAMSN1/CD300A/TNFAIP8L2/VSIG4/IL7R/TLR4/CCL3/FCER1G/JAK3/C1QC/NR1H3/LILRB4/TIGIT/CD274/IL2RA/LY96/CD86/SLA2/HLA-DOA/IRF1 52 BP GO:0050852 T cell receptor signaling pathway 36/363 174/17381 1.08327848516674e-25 9.48824508478397e-24 6.90883492087765e-24 WAS/ZAP70/FYB1/CD3D/LCP2/HLA-DRB1/PSMB10/PTPRC/HLA-DQB1/PSME2/GBP1/HLA-DPA1/CD247/PTPN6/THEMIS2/INPP5D/PIK3CD/FOXP3/PAG1/HLA-DQB2/CD3E/HLA-DRA/BTN3A1/HLA-DQA1/CD3G/CD300A/LCK/CD4/CCR7/HLA-DPB1/LILRB4/HLA-DRB5/PSMB9/PSME1/PLCG2/HLA-DQA2 36 BP GO:0060326 cell chemotaxis 43/363 270/17381 1.19792033295032e-25 1.01925907186458e-23 7.421701912414e-24 RAC2/FPR3/CXCL9/CCL4L1/BIN2/CD74/PREX1/CCL3L1/CCL3L3/CXCR3/VAV1/PIK3CD/C3AR1/AIF1/GPSM3/ITGB2/CCR1/PTK2B/CXCL11/CSF1/GPR183/CXCL10/CCL13/JAML/CCR7/IL16/FPR1/NCKAP1L/CCL3/FCER1G/CORO1A/MPP1/PLA2G7/XCL2/CCL5/CCR5/CMKLR1/TRPM2/CCL4/C5AR1/CXCR4/CCL18/RHOG 43 BP GO:0042119 neutrophil activation 56/363 496/17381 2.01380725940965e-25 1.6658661162561e-23 1.21299501590172e-23 LYZ/CLEC5A/PLEKHO2/COTL1/LAIR1/NFAM1/DOCK2/TLR2/BIN2/PSAP/PREX1/ITGAM/KCNAB2/ADA2/FCGR2A/TNFRSF1B/STK10/LILRB2/PTPRC/MMP25/ARHGAP45/MNDA/GPR84/DOK3/FGR/PTPN6/CTSS/CYBB/OSCAR/FGL2/ITGAX/GMFG/C3AR1/CD14/TBC1D10C/ARHGAP9/ITGB2/CTSZ/MAN2B1/CD300A/TYROBP/ITGAL/FPR1/NCKAP1L/HVCN1/FCER1G/CD53/CCL5/TRPM2/SELL/RAB27A/SLC2A5/C5AR1/RHOG/SLC11A1/HK3 56 BP GO:0031295 T cell costimulation 26/363 76/17381 5.03545298050991e-25 4.05285918269149e-23 2.95107628445247e-23 CD3D/HLA-DRB1/CTLA4/HLA-DQB1/HLA-DPA1/CD247/PDCD1/PTPN6/VAV1/PDCD1LG2/HLA-DQB2/SPN/CD3E/HLA-DRA/HLA-DQA1/CD3G/LCK/CD4/CCR7/HLA-DPB1/CD274/HLA-DRB5/CD5/TNFSF13B/CD86/HLA-DQA2 26 BP GO:0031294 lymphocyte costimulation 26/363 79/17381 1.60609970168933e-24 1.25867497674496e-22 9.16500106781171e-23 CD3D/HLA-DRB1/CTLA4/HLA-DQB1/HLA-DPA1/CD247/PDCD1/PTPN6/VAV1/PDCD1LG2/HLA-DQB2/SPN/CD3E/HLA-DRA/HLA-DQA1/CD3G/LCK/CD4/CCR7/HLA-DPB1/CD274/HLA-DRB5/CD5/TNFSF13B/CD86/HLA-DQA2 26 BP GO:0043312 neutrophil degranulation 54/363 485/17381 3.13567970309851e-24 2.39437286046856e-22 1.74345484166881e-22 LYZ/CLEC5A/PLEKHO2/COTL1/LAIR1/NFAM1/DOCK2/TLR2/BIN2/PSAP/ITGAM/KCNAB2/ADA2/FCGR2A/TNFRSF1B/STK10/LILRB2/PTPRC/MMP25/ARHGAP45/MNDA/GPR84/DOK3/FGR/PTPN6/CTSS/CYBB/OSCAR/FGL2/ITGAX/GMFG/C3AR1/CD14/TBC1D10C/ARHGAP9/ITGB2/CTSZ/MAN2B1/CD300A/TYROBP/ITGAL/FPR1/NCKAP1L/HVCN1/FCER1G/CD53/TRPM2/SELL/RAB27A/SLC2A5/C5AR1/RHOG/SLC11A1/HK3 54 BP GO:0002283 neutrophil activation involved in immune response 54/363 486/17381 3.46452232227279e-24 2.57933686893209e-22 1.87813578523209e-22 LYZ/CLEC5A/PLEKHO2/COTL1/LAIR1/NFAM1/DOCK2/TLR2/BIN2/PSAP/ITGAM/KCNAB2/ADA2/FCGR2A/TNFRSF1B/STK10/LILRB2/PTPRC/MMP25/ARHGAP45/MNDA/GPR84/DOK3/FGR/PTPN6/CTSS/CYBB/OSCAR/FGL2/ITGAX/GMFG/C3AR1/CD14/TBC1D10C/ARHGAP9/ITGB2/CTSZ/MAN2B1/CD300A/TYROBP/ITGAL/FPR1/NCKAP1L/HVCN1/FCER1G/CD53/TRPM2/SELL/RAB27A/SLC2A5/C5AR1/RHOG/SLC11A1/HK3 54 BP GO:0042102 positive regulation of T cell proliferation 28/363 101/17381 5.53711302866625e-24 4.02183478033368e-22 2.92848596638061e-22 ZAP70/EBI3/LILRB2/PTPRC/HAVCR2/HLA-DPA1/PDCD1LG2/FOXP3/SPN/CD3E/AIF1/HLA-E/RASAL3/CD4/NCKAP1L/JAK3/CORO1A/IL12RB1/HLA-DPB1/CCL5/CD274/IL2RA/IL15/TNFSF13B/CD86/HLA-DMB/SASH3/CD6 28 BP GO:0071346 cellular response to interferon-gamma 32/363 144/17381 5.6765802618269e-24 4.02496571898107e-22 2.93076574921389e-22 GBP5/IRF8/GBP2/CCL4L1/HLA-DRB1/HLA-DQB1/GBP1/HLA-DPA1/CCL3L1/CCL3L3/HCK/HLA-DQB2/AIF1/HLA-DRA/MRC1/HLA-E/HLA-DQA1/CCL13/CASP1/CCL3/SOCS1/IL12RB1/XCL2/HLA-DPB1/CCL5/NR1H3/HLA-DRB5/CCL4/CCL18/IFI30/HLA-DQA2/IRF1 32 BP GO:0002446 neutrophil mediated immunity 54/363 499/17381 1.23791363069763e-23 8.57327160980821e-22 6.24259994917285e-22 LYZ/CLEC5A/PLEKHO2/COTL1/LAIR1/NFAM1/DOCK2/TLR2/BIN2/PSAP/ITGAM/KCNAB2/ADA2/FCGR2A/TNFRSF1B/STK10/LILRB2/PTPRC/MMP25/ARHGAP45/MNDA/GPR84/DOK3/FGR/PTPN6/CTSS/CYBB/OSCAR/FGL2/ITGAX/GMFG/C3AR1/CD14/TBC1D10C/ARHGAP9/ITGB2/CTSZ/MAN2B1/CD300A/TYROBP/ITGAL/FPR1/NCKAP1L/HVCN1/FCER1G/CD53/TRPM2/SELL/RAB27A/SLC2A5/C5AR1/RHOG/SLC11A1/HK3 54 BP GO:0030217 T cell differentiation 37/363 225/17381 1.10169505847661e-22 7.45647246396212e-21 5.42940626904739e-21 ZAP70/DOCK2/CD74/PREX1/CD3D/CTLA4/LILRB2/PTPRC/BATF/CD2/VAV1/CD8A/PIK3CD/FOXP3/SPN/CD3E/RASGRP1/GPR183/CD27/IL7R/LCK/CD4/CCR7/NCKAP1L/SOCS1/SLAMF6/FCER1G/JAK3/IL12RB1/LILRB4/ZNF683/IL2RA/IL15/CD86/HLA-DOA/SASH3/IRF1 37 BP GO:0002695 negative regulation of leukocyte activation 30/363 155/17381 1.07779772782347e-20 7.13262585212954e-19 5.19359840775754e-19 LILRB1/CD74/LAG3/CTLA4/LILRB2/CD300LF/HAVCR2/MILR1/MNDA/LST1/PTPN6/IDO1/PDCD1LG2/INPP5D/FOXP3/PAG1/SPN/TBC1D10C/BTK/SAMSN1/CD300A/TNFAIP8L2/VSIG4/JAK3/NR1H3/TIGIT/CD274/IL2RA/SLA2/IRF1 30 BP GO:0050866 negative regulation of cell activation 31/363 174/17381 3.13078724585466e-20 2.02684443872939e-18 1.47584021200471e-18 LILRB1/CD74/LAG3/CTLA4/LILRB2/CD300LF/HAVCR2/MILR1/MNDA/LST1/PTPN6/IDO1/PDCD1LG2/INPP5D/FOXP3/PAG1/SPN/TBC1D10C/BTK/SAMSN1/CD300A/TNFAIP8L2/VSIG4/APOE/JAK3/NR1H3/TIGIT/CD274/IL2RA/SLA2/IRF1 31 BP GO:0001819 positive regulation of cytokine production 45/363 409/17381 4.48763151750267e-20 2.84343971470701e-18 2.07044141680974e-18 MCOLN2/CLEC5A/GBP5/IRF8/NFAM1/EBI3/TLR2/CD74/LILRB2/HAVCR2/HLA-DPA1/CD2/FGR/CYBB/CSF1R/IDO1/FOXP3/C3AR1/SPN/CD14/CD3E/GPSM3/RASGRP1/HLA-E/TLR4/CASP1/CD4/CCR7/CCL3/SLAMF6/FCER1G/CD40/IL12RB1/HLA-DPB1/TIGIT/CD274/IL15/LY96/CD86/C5AR1/SLC11A1/SASH3/PLCG2/IRF1/CD6 45 BP GO:0072676 lymphocyte migration 24/363 92/17381 4.93706352827397e-20 3.06303649733331e-18 2.23034010268517e-18 CXCL9/ZAP70/CCL4L1/DOCK8/STK10/CCL3L1/CCL3L3/CXCR3/GCSAM/PIK3CD/ITGB7/AIF1/PTK2B/CXCL11/GPR183/MYO1G/CXCL10/CCL13/CCR7/CCL3/XCL2/CCL5/CCL4/CCL18 24 BP GO:1902105 regulation of leukocyte differentiation 36/363 254/17381 7.27163044812705e-20 4.41937050500457e-18 3.21795031646439e-18 FLT3LG/ZAP70/NFAM1/LILRB1/CD74/CTLA4/EVI2B/LILRB2/CD2/PTPN6/INPP5D/FOXP3/BTK/CCR1/CSF1/RASGRP1/CD27/TYROBP/IL7R/TLR4/CD4/NCKAP1L/CCL3/SOCS1/JAK3/IL12RB1/C1QC/LILRB4/ZNF683/IL2RA/IKZF3/IL15/CD86/HLA-DOA/SASH3/IRF1 36 BP GO:0097529 myeloid leukocyte migration 31/363 179/17381 7.46352148446773e-20 4.44527339614898e-18 3.23681142273758e-18 MCOLN2/RAC2/CCL4L1/CD74/PREX1/CCL3L1/CCL3L3/VAV1/PIK3CD/C3AR1/AIF1/ITGB2/CCR1/PTK2B/CSF1/CD300A/CXCL10/CCL13/JAML/CCR7/NCKAP1L/CCL3/FCER1G/MPP1/PLA2G7/XCL2/CCL5/CMKLR1/CCL4/C5AR1/CCL18 31 BP GO:0019882 antigen processing and presentation 34/363 223/17381 7.65185503883621e-20 4.4680831971871e-18 3.25342030547009e-18 WAS/CD74/LAG3/HLA-DRB1/HLA-DMA/LILRB2/PSMB10/HLA-DQB1/PSME2/NCF4/HLA-DPA1/CTSS/CYBB/CD8A/RAB33A/HLA-DQB2/HLA-DRA/HLA-E/HLA-DQA1/CCR7/FCER1G/MARCH1/HLA-DPB1/LGMN/HLA-DRB5/RAB27A/HLA-DMB/PSMB9/SLC11A1/HLA-DOA/PSME1/IFI30/HLA-DQA2/TREM2 34 BP GO:0042113 B cell activation 37/363 271/17381 7.96914512017806e-20 4.56386810920966e-18 3.32316577885968e-18 CD79B/DOCK10/ZAP70/NFAM1/CD74/POU2F2/CTLA4/PTPRC/BATF/MNDA/PTPN6/LAT2/INPP5D/PIK3CD/FOXP3/CD38/TBC1D10C/BTK/PTK2B/GPR183/SAMSN1/CD27/CD300A/IL7R/TLR4/NCKAP1L/TNFRSF4/JAK3/CD40/LYL1/MFNG/IKZF3/TNFSF13B/CD86/SLA2/SASH3/PLCG2 37 BP GO:0002449 lymphocyte mediated immunity 39/363 314/17381 2.31497913909467e-19 1.30075620306112e-17 9.47141415399209e-18 WAS/CD96/BTN3A2/LILRB1/CD74/LAG3/SERPING1/POU2F2/PTPRC/HAVCR2/HLA-DQB1/BATF/PTPN6/VAV1/CD8A/INPP5D/FOXP3/SPN/BTK/C1QA/SLAMF7/RASGRP1/HLA-E/MYO1G/CD27/IL7R/BTN3A3/SLAMF6/FCER1G/CD40/CORO1A/IL12RB1/C1QC/GZMB/RAB27A/SLA2/SLC11A1/SASH3/C1QB 39 BP GO:0051250 negative regulation of lymphocyte activation 27/363 133/17381 2.6352055581785e-19 1.45326706523251e-17 1.05819170562334e-17 LILRB1/CD74/LAG3/CTLA4/LILRB2/HAVCR2/MNDA/LST1/PTPN6/IDO1/PDCD1LG2/INPP5D/FOXP3/PAG1/SPN/TBC1D10C/BTK/SAMSN1/CD300A/TNFAIP8L2/VSIG4/JAK3/TIGIT/CD274/IL2RA/SLA2/IRF1 27 BP GO:0097530 granulocyte migration 26/363 124/17381 5.23456437228631e-19 2.83427867284884e-17 2.06377083385833e-17 MCOLN2/RAC2/CCL4L1/CD74/PREX1/CCL3L1/CCL3L3/VAV1/PIK3CD/C3AR1/ITGB2/CSF1/CD300A/CCL13/JAML/CCR7/NCKAP1L/CCL3/FCER1G/MPP1/XCL2/CCL5/CMKLR1/CCL4/C5AR1/CCL18 26 BP GO:0070098 chemokine-mediated signaling pathway 22/363 81/17381 6.98571657686908e-19 3.71490427962788e-17 2.7049955166072e-17 CXCL9/CCL4L1/CCL3L1/CCL3L3/CXCR3/CXCR6/CCRL2/CCR1/PTK2B/CXCL11/CXCL10/CCL13/CCR7/CCL3/XCL2/CCL5/CCR5/CMKLR1/CCL4/CXCR4/CCL18/TREM2 22 BP GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 38/363 314/17381 1.69356231236342e-18 8.84812029161098e-17 6.44273012644255e-17 WAS/IL18BP/EBI3/BTN3A2/LILRB1/CD74/SERPING1/POU2F2/PTPRC/HAVCR2/HLA-DQB1/BATF/PTPN6/CD8A/INPP5D/FOXP3/SPN/BTK/C1QA/HLA-E/MYO1G/CD27/IL7R/TLR4/CD4/BTN3A3/SLAMF6/FCER1G/JAK3/CD40/IL12RB1/C1QC/RAB27A/TNFSF13B/SLA2/SLC11A1/SASH3/C1QB 38 BP GO:0071621 granulocyte chemotaxis 24/363 110/17381 4.58724422839234e-18 2.35531264002628e-16 1.71501326869115e-16 RAC2/CCL4L1/CD74/PREX1/CCL3L1/CCL3L3/VAV1/PIK3CD/C3AR1/ITGB2/CSF1/CCL13/JAML/CCR7/NCKAP1L/CCL3/FCER1G/MPP1/XCL2/CCL5/CMKLR1/CCL4/C5AR1/CCL18 24 BP GO:1990266 neutrophil migration 23/363 101/17381 8.29266213998067e-18 4.18568607675634e-16 3.04779375706694e-16 MCOLN2/RAC2/CCL4L1/CD74/PREX1/CCL3L1/CCL3L3/VAV1/PIK3CD/C3AR1/ITGB2/CCL13/JAML/CCR7/NCKAP1L/CCL3/FCER1G/MPP1/XCL2/CCL5/CCL4/C5AR1/CCL18 23 BP GO:0030593 neutrophil chemotaxis 22/363 90/17381 8.43874197204781e-18 4.1884289321264e-16 3.04979095831903e-16 RAC2/CCL4L1/CD74/PREX1/CCL3L1/CCL3L3/VAV1/PIK3CD/C3AR1/ITGB2/CCL13/JAML/CCR7/NCKAP1L/CCL3/FCER1G/MPP1/XCL2/CCL5/CCL4/C5AR1/CCL18 22 BP GO:1903706 regulation of hemopoiesis 44/363 448/17381 9.64020120496284e-18 4.70631462104579e-16 3.42688774499111e-16 SPI1/GPR171/FLT3LG/ZAP70/NFAM1/LILRB1/CD74/CTLA4/EVI2B/LILRB2/PSMB10/PSME2/CD2/PTPN6/INPP5D/FOXP3/BTK/CCR1/PTK2B/CSF1/RASGRP1/CD27/TYROBP/IL7R/TLR4/CD4/NCKAP1L/CCL3/SOCS1/ETS1/JAK3/IL12RB1/C1QC/LILRB4/ZNF683/IL2RA/IKZF3/IL15/CD86/PSMB9/HLA-DOA/PSME1/SASH3/IRF1 44 BP GO:0045619 regulation of lymphocyte differentiation 27/363 156/17381 1.97443411422206e-17 9.48365289056984e-16 6.90549112953726e-16 FLT3LG/ZAP70/NFAM1/CD74/CTLA4/LILRB2/CD2/PTPN6/INPP5D/FOXP3/BTK/RASGRP1/CD27/IL7R/NCKAP1L/SOCS1/JAK3/IL12RB1/LILRB4/ZNF683/IL2RA/IKZF3/IL15/CD86/HLA-DOA/SASH3/IRF1 27 BP GO:0032496 response to lipopolysaccharide 36/363 316/17381 1.00864484639449e-16 4.76784817867108e-15 3.47169320563516e-15 IL10RA/IL18BP/CD96/LY86/CXCL9/IRF8/LILRB1/TLR2/TNFRSF1B/LILRB2/HAVCR2/CARD16/IDO1/HCK/CD14/CXCL11/MRC1/CD27/CXCL10/TLR4/CASP1/CCR7/CCL3/TNFRSF4/CD40/CCL5/CCR5/NR1H3/LY96/CD86/C5AR1/SLC11A1/PLCG2/CD6/ACP5/TREM2 36 BP GO:0032609 interferon-gamma production 22/363 102/17381 1.5066742749207e-16 7.01074373549037e-15 5.10485033936947e-15 CD96/IRF8/EBI3/BTN3A2/LILRB1/HAVCR2/HLA-DPA1/CD2/PDCD1LG2/FOXP3/CD14/CD3E/BTN3A1/RASGRP1/TLR4/CCR7/SLAMF6/IL12RB1/HLA-DPB1/CD274/SLC11A1/SASH3 22 BP GO:0002697 regulation of immune effector process 40/363 402/17381 2.10389736812123e-16 9.63908671117696e-15 7.0186697624773e-15 WAS/RAC2/CD96/LILRB1/CD74/LAG3/SERPING1/ITGAM/PTPRC/HAVCR2/FGR/PTPN6/VAV1/FOXP3/C3AR1/SPN/ITGB2/BTK/C1QA/RASGRP1/HLA-E/CD300A/APOBEC3G/IL7R/TLR4/SLAMF6/FCER1G/TNFRSF4/JAK3/CD40/IL12RB1/C1QC/ZNF683/IL2RA/IL15/CD86/C5AR1/HLA-DMB/SASH3/C1QB 40 BP GO:0048002 antigen processing and presentation of peptide antigen 28/363 187/17381 2.51862184882611e-16 1.13643270694002e-14 8.27489794032182e-15 CD74/LAG3/HLA-DRB1/HLA-DMA/PSMB10/HLA-DQB1/PSME2/NCF4/HLA-DPA1/CTSS/CYBB/HLA-DQB2/HLA-DRA/HLA-E/HLA-DQA1/FCER1G/MARCH1/HLA-DPB1/LGMN/HLA-DRB5/HLA-DMB/PSMB9/SLC11A1/HLA-DOA/PSME1/IFI30/HLA-DQA2/TREM2 28 BP GO:0002237 response to molecule of bacterial origin 36/363 333/17381 5.4003355510808e-16 2.40032824942069e-14 1.74779123884155e-14 IL10RA/IL18BP/CD96/LY86/CXCL9/IRF8/LILRB1/TLR2/TNFRSF1B/LILRB2/HAVCR2/CARD16/IDO1/HCK/CD14/CXCL11/MRC1/CD27/CXCL10/TLR4/CASP1/CCR7/CCL3/TNFRSF4/CD40/CCL5/CCR5/NR1H3/LY96/CD86/C5AR1/SLC11A1/PLCG2/CD6/ACP5/TREM2 36 BP GO:0002703 regulation of leukocyte mediated immunity 26/363 165/17381 8.50207832365374e-16 3.72341018350601e-14 2.71118906296079e-14 WAS/RAC2/CD96/LILRB1/LAG3/ITGAM/PTPRC/HAVCR2/FGR/PTPN6/VAV1/FOXP3/SPN/ITGB2/BTK/RASGRP1/HLA-E/CD300A/IL7R/TLR4/SLAMF6/FCER1G/JAK3/CD40/IL12RB1/SASH3 26 BP GO:0032649 regulation of interferon-gamma production 20/363 92/17381 3.14310227697581e-15 1.35654472185999e-13 9.87763644633129e-14 CD96/IRF8/EBI3/LILRB1/HAVCR2/HLA-DPA1/CD2/PDCD1LG2/FOXP3/CD14/CD3E/RASGRP1/TLR4/CCR7/SLAMF6/IL12RB1/HLA-DPB1/CD274/SLC11A1/SASH3 20 BP GO:0006909 phagocytosis 34/363 315/17381 3.83269893931621e-15 1.6305396344691e-13 1.18727215263028e-13 WAS/IRF8/DOCK2/TLR2/BIN2/FCGR3A/ITGAM/FCGR2A/WIPF1/CD300LF/NCF4/ARHGAP25/MSR1/FGR/MYO7A/CD247/VAV1/HCK/CD14/AIF1/ITGB2/CD3G/MYO1G/CD300A/ELMO1/ITGAL/NCKAP1L/FCER1G/CORO1A/NR1H3/RAB27A/SLC11A1/PLCG2/TREM2 34 BP GO:0032103 positive regulation of response to external stimulus 32/363 281/17381 5.60275721791299e-15 2.35000154858379e-13 1.71114601466283e-13 GBP5/RAC2/LY86/CXCL9/TLR2/CD74/HAVCR2/IDO1/C3AR1/AIF1/GPSM3/BTK/CCR1/PTK2B/CXCL11/CSF1/CXCL10/TLR4/CCR7/IL16/NCKAP1L/CCL3/FCER1G/ETS1/PLA2G7/CCL5/CMKLR1/IL15/CCL4/LY96/C5AR1/CD6 32 BP GO:0002685 regulation of leukocyte migration 25/363 171/17381 1.85492139822827e-14 7.67216100544969e-13 5.58645918179858e-13 RAC2/CXCL9/CD74/DOCK8/STK10/CXCR3/GCSAM/C3AR1/AIF1/GPSM3/CCR1/PTK2B/CXCL11/CSF1/CD300A/CXCL10/CCR7/NCKAP1L/CCL3/MPP1/PLA2G7/CCL5/CMKLR1/CCL4/C5AR1 25 BP GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 20/363 101/17381 2.12035302759664e-14 8.5329882651119e-13 6.21326776223199e-13 CD74/LAG3/HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DPA1/CTSS/HLA-DQB2/HLA-DRA/HLA-DQA1/FCER1G/MARCH1/HLA-DPB1/LGMN/HLA-DRB5/HLA-DMB/HLA-DOA/IFI30/HLA-DQA2/TREM2 20 BP GO:0050868 negative regulation of T cell activation 20/363 101/17381 2.12035302759664e-14 8.5329882651119e-13 6.21326776223199e-13 LILRB1/CD74/LAG3/CTLA4/LILRB2/HAVCR2/PTPN6/IDO1/PDCD1LG2/FOXP3/PAG1/SPN/CD300A/TNFAIP8L2/VSIG4/JAK3/TIGIT/CD274/IL2RA/IRF1 20 BP GO:0002690 positive regulation of leukocyte chemotaxis 19/363 89/17381 2.23538547474795e-14 8.87597059173251e-13 6.46300923225371e-13 RAC2/CXCL9/CD74/C3AR1/AIF1/GPSM3/CCR1/PTK2B/CXCL11/CSF1/CXCL10/CCR7/NCKAP1L/CCL3/PLA2G7/CCL5/CMKLR1/CCL4/C5AR1 19 BP GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 20/363 102/17381 2.58785215646076e-14 1.01402943709739e-12 7.38362249627307e-13 CD74/LAG3/HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DPA1/CTSS/HLA-DQB2/HLA-DRA/HLA-DQA1/FCER1G/MARCH1/HLA-DPB1/LGMN/HLA-DRB5/HLA-DMB/HLA-DOA/IFI30/HLA-DQA2/TREM2 20 BP GO:0002478 antigen processing and presentation of exogenous peptide antigen 25/363 174/17381 2.79877618892061e-14 1.08243577800072e-12 7.88172105150575e-13 CD74/LAG3/HLA-DRB1/HLA-DMA/PSMB10/HLA-DQB1/PSME2/NCF4/HLA-DPA1/CTSS/CYBB/HLA-DQB2/HLA-DRA/HLA-E/HLA-DQA1/FCER1G/HLA-DPB1/LGMN/HLA-DRB5/HLA-DMB/PSMB9/HLA-DOA/PSME1/IFI30/HLA-DQA2 25 BP GO:0045088 regulation of innate immune response 38/363 422/17381 3.15150797096287e-14 1.20322958173429e-12 8.76127722022067e-13 GBP5/CD96/NLRC3/LILRB1/TLR2/LAG3/SERPING1/ITGAM/TRAFD1/PSMB10/CD300LF/HAVCR2/PSME2/FGR/PTPN6/CTSS/VAV1/HCK/CD14/ITGB2/BTK/CLEC4A/RASGRP1/HLA-E/CD300A/TLR4/SOCS1/SLAMF6/FCER1G/CCL5/NR1H3/LGMN/LY96/CD86/PSMB9/PSME1/PLCG2/IRF1 38 BP GO:0002285 lymphocyte activation involved in immune response 24/363 161/17381 4.02592773277155e-14 1.51762187192325e-12 1.10505144963483e-12 DOCK10/LILRB1/HAVCR2/BATF/FOXP3/LCP1/PTK2B/GPR183/TLR4/ITGAL/SLAMF6/FCER1G/JAK3/CD40/CORO1A/IL12RB1/MFNG/APBB1IP/ZNF683/RAB27A/CD86/HLA-DMB/SLC11A1/PLCG2 24 BP GO:0032945 negative regulation of mononuclear cell proliferation 17/363 69/17381 4.18718944998045e-14 1.53943829407923e-12 1.1209370067524e-12 LILRB1/CTLA4/LILRB2/HAVCR2/MNDA/LST1/PTPN6/IDO1/PDCD1LG2/INPP5D/FOXP3/SPN/BTK/CD300A/VSIG4/CD274/IL2RA 17 BP GO:0050672 negative regulation of lymphocyte proliferation 17/363 69/17381 4.18718944998045e-14 1.53943829407923e-12 1.1209370067524e-12 LILRB1/CTLA4/LILRB2/HAVCR2/MNDA/LST1/PTPN6/IDO1/PDCD1LG2/INPP5D/FOXP3/SPN/BTK/CD300A/VSIG4/CD274/IL2RA 17 BP GO:0048247 lymphocyte chemotaxis 16/363 59/17381 4.57564700272813e-14 1.66174107001517e-12 1.20999137684467e-12 CXCL9/CCL4L1/CCL3L1/CCL3L3/CXCR3/PIK3CD/PTK2B/CXCL11/GPR183/CXCL10/CCL13/CCL3/XCL2/CCL5/CCL4/CCL18 16 BP GO:0043547 positive regulation of GTPase activity 37/363 407/17381 5.21997375799471e-14 1.86144315789446e-12 1.35540380518984e-12 DOCK10/ACAP1/ADAP2/CCL4L1/SMAP2/DOCK2/DOCK8/RGS1/RGS19/PREX1/ARHGAP45/ARHGAP25/AGAP2/ARHGEF6/CCL3L1/CCL3L3/TAGAP/SEMA4D/VAV1/GMIP/TBC1D10C/ARHGAP9/PTK2B/RASGRP1/ARHGDIB/RASAL3/CCL13/CCR7/NCKAP1L/CCL3/CD40/XCL2/CCL5/ARHGAP30/CCL4/CCL18/RHOG 37 BP GO:1902107 positive regulation of leukocyte differentiation 22/363 133/17381 5.25054483758008e-14 1.86144315789446e-12 1.35540380518984e-12 FLT3LG/ZAP70/CD74/EVI2B/LILRB2/INPP5D/FOXP3/BTK/CCR1/CSF1/RASGRP1/CD27/IL7R/CD4/NCKAP1L/SOCS1/IL12RB1/LILRB4/IL2RA/IL15/CD86/SASH3 22 BP GO:0043087 regulation of GTPase activity 40/363 475/17381 5.86255139811942e-14 2.05396212512937e-12 1.49558586750787e-12 DOCK10/ACAP1/ADAP2/CCL4L1/SMAP2/PLXNC1/FGD2/DOCK2/DOCK8/RGS1/RGS19/PREX1/ARHGAP45/ARHGAP25/AGAP2/ARHGEF6/CCL3L1/CCL3L3/TAGAP/SEMA4D/VAV1/GMIP/TBC1D10C/ARHGAP9/FGD3/PTK2B/RASGRP1/ARHGDIB/RASAL3/CCL13/CCR7/NCKAP1L/CCL3/CD40/XCL2/CCL5/ARHGAP30/CCL4/CCL18/RHOG 40 BP GO:0030888 regulation of B cell proliferation 16/363 60/17381 6.12224752746079e-14 2.12000617869514e-12 1.54367563115902e-12 CD74/CTLA4/PTPRC/MNDA/INPP5D/CD38/BTK/GPR183/CD300A/TLR4/NCKAP1L/TNFRSF4/CD40/IKZF3/TNFSF13B/SASH3 16 BP GO:0019884 antigen processing and presentation of exogenous antigen 25/363 181/17381 7.07066011866984e-14 2.42027883142515e-12 1.76231819049726e-12 CD74/LAG3/HLA-DRB1/HLA-DMA/PSMB10/HLA-DQB1/PSME2/NCF4/HLA-DPA1/CTSS/CYBB/HLA-DQB2/HLA-DRA/HLA-E/HLA-DQA1/FCER1G/HLA-DPB1/LGMN/HLA-DRB5/HLA-DMB/PSMB9/HLA-DOA/PSME1/IFI30/HLA-DQA2 25 BP GO:0071674 mononuclear cell migration 18/363 83/17381 8.1607523613731e-14 2.76167278774649e-12 2.01090309383117e-12 CCL4L1/CCL3L1/CCL3L3/C3AR1/AIF1/CCR1/CSF1/CXCL10/CCL13/JAML/CCL3/PLA2G7/XCL2/CCL5/CMKLR1/CCL4/C5AR1/CCL18 18 BP GO:0002688 regulation of leukocyte chemotaxis 20/363 109/17381 9.79684672169536e-14 3.27809095923694e-12 2.38693131244145e-12 RAC2/CXCL9/CD74/C3AR1/AIF1/GPSM3/CCR1/PTK2B/CXCL11/CSF1/CXCL10/CCR7/NCKAP1L/CCL3/MPP1/PLA2G7/CCL5/CMKLR1/CCL4/C5AR1 20 BP GO:0070664 negative regulation of leukocyte proliferation 17/363 73/17381 1.15007095194521e-13 3.80545699432536e-12 2.77093118246447e-12 LILRB1/CTLA4/LILRB2/HAVCR2/MNDA/LST1/PTPN6/IDO1/PDCD1LG2/INPP5D/FOXP3/SPN/BTK/CD300A/VSIG4/CD274/IL2RA 17 BP GO:0045621 positive regulation of lymphocyte differentiation 18/363 85/17381 1.26854475019371e-13 4.1513475451394e-12 3.02279026651132e-12 FLT3LG/ZAP70/CD74/LILRB2/INPP5D/FOXP3/BTK/RASGRP1/CD27/IL7R/NCKAP1L/SOCS1/IL12RB1/LILRB4/IL2RA/IL15/CD86/SASH3 18 BP GO:0050864 regulation of B cell activation 23/363 155/17381 1.53037763559524e-13 4.95376586826371e-12 3.6070685690231e-12 NFAM1/CD74/CTLA4/PTPRC/MNDA/PTPN6/INPP5D/FOXP3/CD38/TBC1D10C/BTK/GPR183/SAMSN1/CD27/CD300A/TLR4/NCKAP1L/TNFRSF4/CD40/IKZF3/TNFSF13B/SLA2/SASH3 23 BP GO:1903038 negative regulation of leukocyte cell-cell adhesion 20/363 112/17381 1.67950870475482e-13 5.37803970189233e-12 3.91600218652511e-12 LILRB1/CD74/LAG3/CTLA4/LILRB2/HAVCR2/PTPN6/IDO1/PDCD1LG2/FOXP3/PAG1/SPN/CD300A/TNFAIP8L2/VSIG4/JAK3/TIGIT/CD274/IL2RA/IRF1 20 BP GO:0031349 positive regulation of defense response 38/363 451/17381 2.56306622799625e-13 8.12001194358812e-12 5.9125603915703e-12 GBP5/TLR2/LAG3/ITGAM/PSMB10/CD300LF/HAVCR2/PSME2/CTSS/VAV1/IDO1/HCK/CD14/GPSM3/ITGB2/BTK/CLEC4A/RASGRP1/HLA-E/CD300A/TLR4/CCR7/CCL3/SLAMF6/FCER1G/ETS1/PLA2G7/CCL5/NR1H3/LGMN/IL15/LY96/CD86/PSMB9/PSME1/PLCG2/IRF1/CD6 38 BP GO:0045580 regulation of T cell differentiation 21/363 129/17381 2.75976192383065e-13 8.65112737807122e-12 6.29929037461621e-12 ZAP70/CD74/CTLA4/LILRB2/CD2/FOXP3/RASGRP1/CD27/IL7R/NCKAP1L/SOCS1/JAK3/IL12RB1/LILRB4/ZNF683/IL2RA/IL15/CD86/HLA-DOA/SASH3/IRF1 21 BP GO:0060333 interferon-gamma-mediated signaling pathway 18/363 89/17381 2.95443631752547e-13 9.16490765999048e-12 6.67339782248078e-12 IRF8/GBP2/HLA-DRB1/HLA-DQB1/GBP1/HLA-DPA1/HCK/HLA-DQB2/HLA-DRA/HLA-E/HLA-DQA1/SOCS1/HLA-DPB1/NR1H3/HLA-DRB5/IFI30/HLA-DQA2/IRF1 18 BP GO:0046631 alpha-beta T cell activation 20/363 119/17381 5.53234465200581e-13 1.69848684264673e-11 1.23674769214671e-11 ZAP70/EBI3/LILRB1/DOCK2/BATF/FOXP3/CD3E/HLA-E/GPR183/RASAL3/CD300A/NCKAP1L/SLAMF6/JAK3/IL12RB1/ZNF683/IL15/CD86/SASH3/IRF1 20 BP GO:0002819 regulation of adaptive immune response 21/363 135/17381 6.93547593696835e-13 2.10753544288691e-11 1.53459510527979e-11 WAS/LILRB1/CD48/PTPRC/HAVCR2/PTPN6/FOXP3/SPN/BTK/HLA-E/SAMSN1/IL7R/CD4/FCER1G/JAK3/CD40/IL12RB1/TNFSF13B/SLC11A1/SASH3/IRF1 21 BP GO:1903708 positive regulation of hemopoiesis 23/363 169/17381 9.95102633609877e-13 2.99334913423254e-11 2.17959747499877e-11 FLT3LG/ZAP70/CD74/EVI2B/LILRB2/INPP5D/FOXP3/BTK/CCR1/CSF1/RASGRP1/CD27/IL7R/CD4/NCKAP1L/SOCS1/ETS1/IL12RB1/LILRB4/IL2RA/IL15/CD86/SASH3 23 BP GO:0002687 positive regulation of leukocyte migration 20/363 123/17381 1.05283320610476e-12 3.13533728777998e-11 2.28298568902717e-11 RAC2/CXCL9/CD74/DOCK8/C3AR1/AIF1/GPSM3/CCR1/PTK2B/CXCL11/CSF1/CXCL10/CCR7/NCKAP1L/CCL3/PLA2G7/CCL5/CMKLR1/CCL4/C5AR1 20 BP GO:0006968 cellular defense response 15/363 60/17381 1.06704612687662e-12 3.14620135231541e-11 2.290896322424e-11 CLEC5A/CXCL9/FCMR/LILRB2/MNDA/GNLY/SPN/PTK2B/PRF1/CD300C/TYROBP/LSP1/CCR5/LY96/C5AR1 15 BP GO:0071219 cellular response to molecule of bacterial origin 23/363 173/17381 1.64068320315579e-12 4.79015154803719e-11 3.4879333317863e-11 LY86/IRF8/LILRB1/TLR2/TNFRSF1B/LILRB2/HAVCR2/CARD16/HCK/CD14/MRC1/CXCL10/TLR4/CASP1/CCL3/CD40/CCL5/CCR5/NR1H3/LY96/CD86/CD6/TREM2 23 BP GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 18/363 98/17381 1.68975083783668e-12 4.88551261658024e-11 3.55737018491934e-11 CD74/LAG3/HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DPA1/CTSS/HLA-DQB2/HLA-DRA/HLA-DQA1/FCER1G/HLA-DPB1/LGMN/HLA-DRB5/HLA-DMB/HLA-DOA/IFI30/HLA-DQA2 18 BP GO:0007162 negative regulation of cell adhesion 27/363 248/17381 2.36839293089148e-12 6.78180206557195e-11 4.93814720408548e-11 PLXNC1/LILRB1/CD74/LAG3/CTLA4/LILRB2/PTPRC/HAVCR2/GBP1/PTPN6/SEMA4D/IDO1/PDCD1LG2/FOXP3/PAG1/SPN/LPXN/ARHGDIB/CD300A/TNFAIP8L2/VSIG4/JAK3/ADAMDEC1/TIGIT/CD274/IL2RA/IRF1 27 BP GO:0071216 cellular response to biotic stimulus 24/363 195/17381 2.91153830357841e-12 8.20042845626313e-11 5.9711154147616e-11 LY86/IRF8/LILRB1/TLR2/TNFRSF1B/LILRB2/HAVCR2/CARD16/HCK/CD14/BTK/MRC1/CXCL10/TLR4/CASP1/CCL3/CD40/CCL5/CCR5/NR1H3/LY96/CD86/CD6/TREM2 24 BP GO:1903555 regulation of tumor necrosis factor superfamily cytokine production 19/363 115/17381 2.91888991391502e-12 8.20042845626313e-11 5.9711154147616e-11 NLRC3/LILRB1/TLR2/HAVCR2/CD2/CYBB/FOXP3/SPN/CD14/RASGRP1/HLA-E/TLR4/CCL3/FCER1G/CD274/LY96/CD86/SASH3/ACP5 19 BP GO:0050663 cytokine secretion 24/363 197/17381 3.63724023391258e-12 1.0123085436067e-10 7.37109186606976e-11 MCOLN2/CLEC5A/GBP5/BTN3A2/LILRB1/TLR2/LCP2/HAVCR2/CARD16/GBP1/CD2/FGR/CSF1R/SRGN/FOXP3/CD14/BTN3A1/RASGRP1/TLR4/CASP1/CCR7/CCL3/SOCS1/CD274 24 BP GO:0050777 negative regulation of immune response 20/363 132/17381 4.09690587945651e-12 1.11931978981848e-10 8.15029078868218e-11 CD96/NLRC3/LILRB1/SERPING1/TRAFD1/CTLA4/LILRB2/PTPRC/HAVCR2/PTPN6/INPP5D/FOXP3/SPN/HLA-E/SAMSN1/CD300A/IL7R/JAK3/NR1H3/IL2RA 20 BP GO:0050921 positive regulation of chemotaxis 20/363 132/17381 4.09690587945651e-12 1.11931978981848e-10 8.15029078868218e-11 RAC2/CXCL9/CD74/C3AR1/AIF1/GPSM3/CCR1/PTK2B/CXCL11/CSF1/CXCL10/CCR7/IL16/NCKAP1L/CCL3/PLA2G7/CCL5/CMKLR1/CCL4/C5AR1 20 BP GO:0071222 cellular response to lipopolysaccharide 22/363 165/17381 4.76760589253668e-12 1.29072094072493e-10 9.39834271638809e-11 LY86/IRF8/LILRB1/TLR2/TNFRSF1B/LILRB2/HAVCR2/CARD16/HCK/CD14/MRC1/CXCL10/TLR4/CASP1/CCL3/CD40/CCL5/CCR5/NR1H3/LY96/CD86/CD6 22 BP GO:0071706 tumor necrosis factor superfamily cytokine production 19/363 119/17381 5.47823609354477e-12 1.46974658437625e-10 1.07019121410168e-10 NLRC3/LILRB1/TLR2/HAVCR2/CD2/CYBB/FOXP3/SPN/CD14/RASGRP1/HLA-E/TLR4/CCL3/FCER1G/CD274/LY96/CD86/SASH3/ACP5 19 BP GO:0050920 regulation of chemotaxis 23/363 184/17381 6.04641721055185e-12 1.60769914759138e-10 1.17064092610308e-10 RAC2/CXCL9/CD74/C3AR1/AIF1/GPSM3/CCR1/PTK2B/CXCL11/CSF1/GPR183/CXCL10/CCR7/IL16/NCKAP1L/CCL3/MPP1/PLA2G7/CCL5/CMKLR1/CCL4/C5AR1/CXCR4 23 BP GO:0042100 B cell proliferation 17/363 93/17381 7.67672255729841e-12 2.02312210403847e-10 1.4731298060582e-10 CD74/CTLA4/PTPRC/MNDA/INPP5D/CD38/BTK/GPR183/CD300A/IL7R/TLR4/NCKAP1L/TNFRSF4/CD40/IKZF3/TNFSF13B/SASH3 17 BP GO:0045058 T cell selection 13/363 47/17381 8.60728075905582e-12 2.24846334214634e-10 1.6372112985831e-10 ZAP70/DOCK2/CD74/CD3D/BATF/FOXP3/SPN/CD3E/CD4/CCR7/SLAMF6/IL12RB1/IL15 13 BP GO:0002706 regulation of lymphocyte mediated immunity 19/363 124/17381 1.16156152302166e-11 3.00793931787696e-10 2.19022126995389e-10 WAS/CD96/LILRB1/LAG3/PTPRC/HAVCR2/PTPN6/VAV1/FOXP3/SPN/BTK/RASGRP1/HLA-E/IL7R/SLAMF6/FCER1G/CD40/IL12RB1/SASH3 19 BP GO:0002699 positive regulation of immune effector process 22/363 174/17381 1.39904787929127e-11 3.59169360735294e-10 2.61528006473686e-10 RAC2/LILRB1/CD74/LAG3/ITGAM/FGR/VAV1/FOXP3/ITGB2/BTK/RASGRP1/HLA-E/CD300A/TLR4/SLAMF6/FCER1G/TNFRSF4/CD40/IL12RB1/CD86/HLA-DMB/SASH3 22 BP GO:0072678 T cell migration 13/363 49/17381 1.54722256600595e-11 3.93814427484251e-10 2.86754699592646e-10 CXCL9/ZAP70/DOCK8/CXCR3/PIK3CD/ITGB7/AIF1/CXCL11/GPR183/MYO1G/CXCL10/CCL3/CCL5 13 BP GO:0032729 positive regulation of interferon-gamma production 14/363 63/17381 3.46585726014979e-11 8.7468838311238e-10 6.36901512569899e-10 IRF8/EBI3/HAVCR2/HLA-DPA1/CD2/CD14/CD3E/RASGRP1/TLR4/SLAMF6/IL12RB1/HLA-DPB1/SLC11A1/SASH3 14 BP GO:0045089 positive regulation of innate immune response 30/363 348/17381 5.40244113612772e-11 1.35197224398222e-09 9.84434209679179e-10 GBP5/TLR2/LAG3/ITGAM/PSMB10/CD300LF/HAVCR2/PSME2/CTSS/VAV1/HCK/CD14/ITGB2/BTK/CLEC4A/RASGRP1/HLA-E/CD300A/TLR4/SLAMF6/FCER1G/CCL5/NR1H3/LGMN/LY96/CD86/PSMB9/PSME1/PLCG2/IRF1 30 BP GO:0050853 B cell receptor signaling pathway 16/363 92/17381 7.03198488047913e-11 1.7451042478389e-09 1.27069200471816e-09 CD79B/NFAM1/CTLA4/PTPRC/MNDA/PTPN6/LAT2/GCSAM/PIK3CD/CD38/LPXN/BTK/CD300A/LCK/NCKAP1L/PLCG2 16 BP GO:0046634 regulation of alpha-beta T cell activation 15/363 79/17381 7.54683471319832e-11 1.85739452693426e-09 1.3524558076719e-09 ZAP70/EBI3/LILRB1/FOXP3/CD3E/HLA-E/RASAL3/CD300A/NCKAP1L/JAK3/IL12RB1/ZNF683/CD86/SASH3/IRF1 15 BP GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production 14/363 67/17381 8.411490473705e-11 2.05323103530275e-09 1.49505352681901e-09 TLR2/HAVCR2/CD2/CYBB/SPN/CD14/RASGRP1/HLA-E/TLR4/CCL3/FCER1G/LY96/CD86/SASH3 14 BP GO:0001906 cell killing 19/363 139/17381 9.01454372348674e-11 2.18254562671085e-09 1.58921352763224e-09 LYZ/LILRB1/LAG3/PTPRC/HAVCR2/GNLY/PTPN6/VAV1/PRF1/SLAMF7/RASGRP1/HLA-E/CCL13/IL7R/SLAMF6/CORO1A/IL12RB1/GZMB/RAB27A 19 BP GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 18/363 124/17381 1.02861214559384e-10 2.47032820127296e-09 1.7987614770147e-09 WAS/LILRB1/PTPRC/HAVCR2/PTPN6/FOXP3/SPN/BTK/HLA-E/IL7R/CD4/FCER1G/JAK3/CD40/IL12RB1/TNFSF13B/SLC11A1/SASH3 18 BP GO:0022408 negative regulation of cell-cell adhesion 20/363 157/17381 1.05238233646214e-10 2.50719567838739e-09 1.82560641104168e-09 LILRB1/CD74/LAG3/CTLA4/LILRB2/HAVCR2/PTPN6/IDO1/PDCD1LG2/FOXP3/PAG1/SPN/CD300A/TNFAIP8L2/VSIG4/JAK3/TIGIT/CD274/IL2RA/IRF1 20 BP GO:0002286 T cell activation involved in immune response 16/363 96/17381 1.36913075680222e-10 3.23592967758492e-09 2.35623171178994e-09 LILRB1/HAVCR2/BATF/FOXP3/LCP1/GPR183/ITGAL/SLAMF6/FCER1G/JAK3/IL12RB1/APBB1IP/RAB27A/CD86/HLA-DMB/SLC11A1 16 BP GO:0050727 regulation of inflammatory response 31/363 385/17381 1.42789640237828e-10 3.34824841439569e-09 2.43801623613697e-09 GBP5/NLRC3/TLR2/SERPING1/TNFRSF1B/IDO1/FOXP3/HCK/C3AR1/SPN/GPSM3/BTK/C1QA/TNFAIP8L2/TLR4/CASP1/CCR7/CCL3/APOE/FCER1G/ETS1/PLA2G7/CCL5/C1QC/NR1H3/IL2RA/IL15/C5AR1/C1QB/CD6/ACP5 31 BP GO:0002456 T cell mediated immunity 15/363 83/17381 1.57871071255539e-10 3.67296914217964e-09 2.67446058212508e-09 WAS/BTN3A2/LILRB1/PTPRC/CD8A/FOXP3/SPN/HLA-E/MYO1G/IL7R/BTN3A3/IL12RB1/RAB27A/SLC11A1/SASH3 15 BP GO:0032680 regulation of tumor necrosis factor production 17/363 112/17381 1.66756494107682e-10 3.84961891048587e-09 2.80308753865218e-09 NLRC3/LILRB1/TLR2/HAVCR2/CD2/CYBB/FOXP3/SPN/CD14/RASGRP1/HLA-E/TLR4/CCL3/FCER1G/LY96/SASH3/ACP5 17 BP GO:0030099 myeloid cell differentiation 31/363 390/17381 1.9697305597749e-10 4.51219815923819e-09 3.28554247217513e-09 SPI1/CLEC5A/GPR171/IRF8/LILRB1/TLR2/CD74/EVI2B/BATF/PTPN6/CSF1R/INPP5D/PIK3CD/CCR1/PTK2B/CSF1/GPR183/TYROBP/FLI1/TLR4/CD4/CCR7/NCKAP1L/CCL3/ETS1/JAK3/C1QC/LILRB4/IKZF1/SNX10/CD86 31 BP GO:0032640 tumor necrosis factor production 17/363 114/17381 2.2209495549144e-10 5.04884562941609e-09 3.67630058909093e-09 NLRC3/LILRB1/TLR2/HAVCR2/CD2/CYBB/FOXP3/SPN/CD14/RASGRP1/HLA-E/TLR4/CCL3/FCER1G/LY96/SASH3/ACP5 17 BP GO:0002228 natural killer cell mediated immunity 13/363 61/17381 3.08557932099316e-10 6.9612539529679e-09 5.06881451455017e-09 CD96/LILRB1/LAG3/HAVCR2/PTPN6/VAV1/SLAMF7/RASGRP1/HLA-E/SLAMF6/CORO1A/GZMB/RAB27A 13 BP GO:0032655 regulation of interleukin-12 production 12/363 50/17381 3.41704185927047e-10 7.63140016620488e-09 5.55677930874909e-09 IRF8/LILRB1/TLR2/IDO1/TLR4/CCR7/JAK3/CD40/CMKLR1/TIGIT/IRF1/ACP5 12 BP GO:0045582 positive regulation of T cell differentiation 14/363 74/17381 3.43387381555223e-10 7.63140016620488e-09 5.55677930874909e-09 ZAP70/CD74/LILRB2/FOXP3/RASGRP1/CD27/IL7R/NCKAP1L/SOCS1/IL12RB1/LILRB4/IL2RA/CD86/SASH3 14 BP GO:0001909 leukocyte mediated cytotoxicity 15/363 88/17381 3.7457281577405e-10 8.26279885463052e-09 6.01653021828104e-09 LILRB1/LAG3/PTPRC/HAVCR2/PTPN6/VAV1/SLAMF7/RASGRP1/HLA-E/IL7R/SLAMF6/CORO1A/IL12RB1/GZMB/RAB27A 15 BP GO:0002573 myeloid leukocyte differentiation 21/363 189/17381 4.7373308053592e-10 1.02976872207028e-08 7.49822758992183e-09 SPI1/LILRB1/TLR2/CD74/EVI2B/BATF/CSF1R/INPP5D/PIK3CD/CCR1/CSF1/GPR183/TYROBP/TLR4/CD4/CCR7/CCL3/C1QC/LILRB4/SNX10/CD86 21 BP GO:0002548 monocyte chemotaxis 13/363 63/17381 4.73735107198216e-10 1.02976872207028e-08 7.49822758992183e-09 CCL4L1/CCL3L1/CCL3L3/AIF1/CCR1/CXCL10/CCL13/CCL3/PLA2G7/XCL2/CCL5/CCL4/CCL18 13 BP GO:0032615 interleukin-12 production 12/363 52/17381 5.59480812148445e-10 1.20734337578121e-08 8.79123167830509e-09 IRF8/LILRB1/TLR2/IDO1/TLR4/CCR7/JAK3/CD40/CMKLR1/TIGIT/IRF1/ACP5 12 BP GO:0002643 regulation of tolerance induction 8/363 17/17381 6.9153146660203e-10 1.48156885434593e-08 1.07879956168132e-08 LILRB2/HAVCR2/PDCD1/IDO1/FOXP3/CD3E/IL2RA/CD86 8 BP GO:0032760 positive regulation of tumor necrosis factor production 13/363 65/17381 7.15632344575317e-10 1.52225223010378e-08 1.10842302994372e-08 TLR2/HAVCR2/CD2/CYBB/SPN/CD14/RASGRP1/HLA-E/TLR4/CCL3/FCER1G/LY96/SASH3 13 BP GO:0048872 homeostasis of number of cells 23/363 233/17381 7.42929764008697e-10 1.56910981362972e-08 1.14254222759083e-08 DOCK10/SPI1/FLT3LG/SIT1/CD74/CD7/INPP5D/PIK3CD/FOXP3/CSF1/LIPA/GPR183/IL7R/CCR7/NCKAP1L/FCER1G/ETS1/JAK3/CORO1A/IKZF1/IL2RA/TNFSF13B/SASH3 23 BP GO:0019932 second-messenger-mediated signaling 26/363 300/17381 9.69439996236653e-10 2.03309317520616e-08 1.48039020922721e-08 CXCL9/ZAP70/GBP1/CLIC2/CXCR3/LAT2/CD8A/CD3E/BTK/PTK2B/GNG2/CXCL11/CXCL10/CD4/FPR1/CCL3/APOE/CCR5/CMKLR1/S1PR4/TRPM2/CCL4/SLA2/CXCR4/PLCG2/TREM2 26 BP GO:0042130 negative regulation of T cell proliferation 12/363 55/17381 1.12421488378103e-09 2.34119714958036e-08 1.70473512005074e-08 LILRB1/CTLA4/LILRB2/HAVCR2/PTPN6/IDO1/PDCD1LG2/FOXP3/SPN/VSIG4/CD274/IL2RA 12 BP GO:0032653 regulation of interleukin-10 production 11/363 44/17381 1.17345567065331e-09 2.42677151889275e-08 1.76704581984344e-08 LILRB1/TLR2/IDO1/PDCD1LG2/FOXP3/TLR4/FCER1G/JAK3/TIGIT/CD274/SASH3 11 BP GO:2000106 regulation of leukocyte apoptotic process 14/363 81/17381 1.20295932321251e-09 2.47062956174265e-08 1.79898091166444e-08 LILRB1/CD74/DOCK8/PDCD1/IDO1/PIK3CD/BTK/CD3G/CD27/CCR7/FCER1G/JAK3/CCL5/CD274 14 BP GO:0070374 positive regulation of ERK1 and ERK2 cascade 21/363 199/17381 1.22824411252929e-09 2.50528148432345e-08 1.82421259683515e-08 CCL4L1/CD74/HAVCR2/CCL3L1/CCL3L3/CSF1R/CCR1/PTK2B/RASGRP1/GPR183/CCL13/TLR4/CD4/CCR7/CCL3/XCL2/CCL5/CCL4/C5AR1/CCL18/TREM2 21 BP GO:0007204 positive regulation of cytosolic calcium ion concentration 25/363 285/17381 1.60220446490895e-09 3.24582646020331e-08 2.36343802199244e-08 FPR3/CXCL9/PTPRC/CLIC2/CXCR3/PTPN6/C3AR1/CD38/CCR1/PTK2B/CXCL11/CXCL10/LCK/CD4/CCR7/FPR1/CCL3/CORO1A/CCR5/S1PR4/TRPM2/C5AR1/CXCR4/PLCG2/CD52 25 BP GO:0042267 natural killer cell mediated cytotoxicity 12/363 57/17381 1.74557683217758e-09 3.51238365285461e-08 2.55753077829716e-08 LILRB1/LAG3/HAVCR2/PTPN6/VAV1/SLAMF7/RASGRP1/HLA-E/SLAMF6/CORO1A/GZMB/RAB27A 12 BP GO:0032613 interleukin-10 production 11/363 46/17381 1.96630255363764e-09 3.92996577498851e-08 2.86159184775241e-08 LILRB1/TLR2/IDO1/PDCD1LG2/FOXP3/TLR4/FCER1G/JAK3/TIGIT/CD274/SASH3 11 BP GO:0019722 calcium-mediated signaling 19/363 167/17381 2.16672405453564e-09 4.30166948960476e-08 3.13224670339889e-08 ZAP70/GBP1/CLIC2/CXCR3/LAT2/CD8A/CD3E/BTK/PTK2B/CD4/CCL3/CCR5/CMKLR1/TRPM2/CCL4/SLA2/CXCR4/PLCG2/TREM2 19 BP GO:0071887 leukocyte apoptotic process 15/363 100/17381 2.38304481629913e-09 4.6998062668469e-08 3.42214870796529e-08 LILRB1/CD74/DOCK8/PDCD1/IDO1/PIK3CD/BTK/CD3G/CD27/CCR7/FCER1G/JAK3/CCL5/CD274/IL2RA 15 BP GO:0002704 negative regulation of leukocyte mediated immunity 11/363 47/17381 2.51957314607398e-09 4.93637422961074e-08 3.59440490367895e-08 CD96/LILRB1/PTPRC/HAVCR2/PTPN6/FOXP3/SPN/HLA-E/CD300A/IL7R/JAK3 11 BP GO:0030183 B cell differentiation 16/363 118/17381 3.1728853107061e-09 6.17572055900834e-08 4.49683091851019e-08 CD79B/DOCK10/NFAM1/POU2F2/PTPN6/INPP5D/BTK/PTK2B/GPR183/CD27/NCKAP1L/JAK3/LYL1/MFNG/IKZF3/PLCG2 16 BP GO:0070372 regulation of ERK1 and ERK2 cascade 24/363 274/17381 3.52972440354178e-09 6.82566186606976e-08 4.97008357573211e-08 CCL4L1/CD74/HAVCR2/GBP1/CCL3L1/CCL3L3/PTPN6/CSF1R/TBC1D10C/CCR1/PTK2B/RASGRP1/GPR183/CCL13/TLR4/CD4/CCR7/CCL3/XCL2/CCL5/CCL4/C5AR1/CCL18/TREM2 24 BP GO:0050707 regulation of cytokine secretion 19/363 172/17381 3.56390486510041e-09 6.84729592791549e-08 4.98583634778053e-08 CLEC5A/LILRB1/TLR2/HAVCR2/CARD16/GBP1/CD2/FGR/CSF1R/SRGN/FOXP3/CD14/RASGRP1/TLR4/CASP1/CCR7/CCL3/SOCS1/CD274 19 BP GO:0030335 positive regulation of cell migration 31/363 442/17381 4.12779750323911e-09 7.87985959272184e-08 5.73769423527163e-08 RAC2/CXCL9/CD74/DOCK8/FERMT3/PREX1/PTPRC/FGR/SEMA4D/CSF1R/PIK3CD/C3AR1/AIF1/GPSM3/CCR1/PTK2B/CXCL11/CSF1/CXCL10/CCR7/NCKAP1L/CCL3/ETS1/CD40/CORO1A/PLA2G7/CCL5/CMKLR1/CD274/CCL4/C5AR1 31 BP GO:0010818 T cell chemotaxis 8/363 22/17381 8.30121108136122e-09 1.57458640766202e-07 1.14652999179377e-07 CXCL9/CXCR3/PIK3CD/CXCL11/GPR183/CXCL10/CCL3/CCL5 8 BP GO:0072507 divalent inorganic cation homeostasis 31/363 456/17381 8.60890544547949e-09 1.62261521624291e-07 1.1815020131704e-07 FPR3/CXCL9/PTPRC/CLIC2/CXCR3/PTPN6/TMC8/C3AR1/CD38/CCR1/PTK2B/CXCL11/CXCL10/CCL13/LCK/CD4/CCR7/FPR1/CCL3/APOE/CD40/CORO1A/CCL5/CCR5/S1PR4/TRPM2/C5AR1/CXCR4/SLC11A1/PLCG2/CD52 31 BP GO:0030890 positive regulation of B cell proliferation 10/363 41/17381 8.7931483797876e-09 1.64691797956022e-07 1.19919799154998e-07 CD74/PTPRC/CD38/GPR183/TLR4/NCKAP1L/TNFRSF4/CD40/TNFSF13B/SASH3 10 BP GO:0050869 negative regulation of B cell activation 9/363 31/17381 9.20187756804363e-09 1.71269946235212e-07 1.24709656514276e-07 CTLA4/MNDA/INPP5D/FOXP3/TBC1D10C/BTK/SAMSN1/CD300A/SLA2 9 BP GO:0001818 negative regulation of cytokine production 22/363 245/17381 1.02098483429595e-08 1.88850486741202e-07 1.3751087013074e-07 CD96/NLRC3/LILRB1/LAG3/HAVCR2/CARD16/GBP1/SRGN/IDO1/PDCD1LG2/INPP5D/FOXP3/BTK/VSIG4/TLR4/NCKAP1L/JAK3/CMKLR1/TIGIT/CD274/SLC11A1/ACP5 22 BP GO:2000147 positive regulation of cell motility 31/363 460/17381 1.05588194825056e-08 1.9409978036359e-07 1.41333126276553e-07 RAC2/CXCL9/CD74/DOCK8/FERMT3/PREX1/PTPRC/FGR/SEMA4D/CSF1R/PIK3CD/C3AR1/AIF1/GPSM3/CCR1/PTK2B/CXCL11/CSF1/CXCL10/CCR7/NCKAP1L/CCL3/ETS1/CD40/CORO1A/PLA2G7/CCL5/CMKLR1/CD274/CCL4/C5AR1 31 BP GO:0070371 ERK1 and ERK2 cascade 24/363 290/17381 1.07825918239227e-08 1.96997291114367e-07 1.43442939343112e-07 CCL4L1/CD74/HAVCR2/GBP1/CCL3L1/CCL3L3/PTPN6/CSF1R/TBC1D10C/CCR1/PTK2B/RASGRP1/GPR183/CCL13/TLR4/CD4/CCR7/CCL3/XCL2/CCL5/CCL4/C5AR1/CCL18/TREM2 24 BP GO:0072503 cellular divalent inorganic cation homeostasis 30/363 438/17381 1.27635171833042e-08 2.31412352003963e-07 1.68502154440693e-07 FPR3/CXCL9/PTPRC/CLIC2/CXCR3/PTPN6/C3AR1/CD38/CCR1/PTK2B/CXCL11/CXCL10/CCL13/LCK/CD4/CCR7/FPR1/CCL3/APOE/CD40/CORO1A/CCL5/CCR5/S1PR4/TRPM2/C5AR1/CXCR4/SLC11A1/PLCG2/CD52 30 BP GO:0040017 positive regulation of locomotion 32/363 490/17381 1.28217051983391e-08 2.31412352003963e-07 1.68502154440693e-07 RAC2/CXCL9/CD74/DOCK8/FERMT3/PREX1/PTPRC/FGR/SEMA4D/CSF1R/PIK3CD/C3AR1/AIF1/GPSM3/CCR1/PTK2B/CXCL11/CSF1/CXCL10/CCR7/IL16/NCKAP1L/CCL3/ETS1/CD40/CORO1A/PLA2G7/CCL5/CMKLR1/CD274/CCL4/C5AR1 32 BP GO:0006874 cellular calcium ion homeostasis 29/363 413/17381 1.30118281969132e-08 2.33429062472334e-07 1.6997061563501e-07 FPR3/CXCL9/PTPRC/CLIC2/CXCR3/PTPN6/C3AR1/CD38/CCR1/PTK2B/CXCL11/CXCL10/CCL13/LCK/CD4/CCR7/FPR1/CCL3/APOE/CD40/CORO1A/CCL5/CCR5/S1PR4/TRPM2/C5AR1/CXCR4/PLCG2/CD52 29 BP GO:0002705 positive regulation of leukocyte mediated immunity 14/363 97/17381 1.3641020678635e-08 2.43251254975898e-07 1.77122613287034e-07 LAG3/ITGAM/FGR/VAV1/FOXP3/ITGB2/BTK/RASGRP1/HLA-E/SLAMF6/FCER1G/CD40/IL12RB1/SASH3 14 BP GO:0051480 regulation of cytosolic calcium ion concentration 25/363 318/17381 1.48599454635096e-08 2.63410223751973e-07 1.91801301095424e-07 FPR3/CXCL9/PTPRC/CLIC2/CXCR3/PTPN6/C3AR1/CD38/CCR1/PTK2B/CXCL11/CXCL10/LCK/CD4/CCR7/FPR1/CCL3/CORO1A/CCR5/S1PR4/TRPM2/C5AR1/CXCR4/PLCG2/CD52 25 BP GO:0034612 response to tumor necrosis factor 24/363 297/17381 1.71321321792759e-08 3.01890471182743e-07 2.19820568603602e-07 IL18BP/CCL4L1/TNFRSF1B/PSMB10/PSME2/CARD16/NUB1/CCL3L1/CCL3L3/CD14/PTK2B/CD27/CCL13/CASP1/CCL3/TNFRSF4/CD40/XCL2/CCL5/CCL4/TNFSF13B/CCL18/PSMB9/PSME1 24 BP GO:0045576 mast cell activation 11/363 56/17381 1.82061252364387e-08 3.18928476200673e-07 2.32226736762004e-07 RAC2/LCP2/CD300LF/MILR1/FGR/LAT2/PIK3CD/BTK/RASGRP1/CD300A/FCER1G 11 BP GO:0051272 positive regulation of cellular component movement 31/363 473/17381 2.01530531447225e-08 3.5096954540926e-07 2.55557337507715e-07 RAC2/CXCL9/CD74/DOCK8/FERMT3/PREX1/PTPRC/FGR/SEMA4D/CSF1R/PIK3CD/C3AR1/AIF1/GPSM3/CCR1/PTK2B/CXCL11/CSF1/CXCL10/CCR7/NCKAP1L/CCL3/ETS1/CD40/CORO1A/PLA2G7/CCL5/CMKLR1/CD274/CCL4/C5AR1 31 BP GO:0055074 calcium ion homeostasis 29/363 424/17381 2.32426929292395e-08 4.02422904321367e-07 2.93022934114035e-07 FPR3/CXCL9/PTPRC/CLIC2/CXCR3/PTPN6/C3AR1/CD38/CCR1/PTK2B/CXCL11/CXCL10/CCL13/LCK/CD4/CCR7/FPR1/CCL3/APOE/CD40/CORO1A/CCL5/CCR5/S1PR4/TRPM2/C5AR1/CXCR4/PLCG2/CD52 29 BP GO:0002577 regulation of antigen processing and presentation 7/363 17/17381 2.65742856192049e-08 4.54904344737571e-07 3.31237124937046e-07 WAS/CD74/LILRB2/CCR7/SLC11A1/HLA-DOA/TREM2 7 BP GO:0002507 tolerance induction 8/363 25/17381 2.65793673553853e-08 4.54904344737571e-07 3.31237124937046e-07 LILRB2/HAVCR2/PDCD1/IDO1/FOXP3/CD3E/IL2RA/CD86 8 BP GO:0002758 innate immune response-activating signal transduction 23/363 284/17381 3.28780508072345e-08 5.59490487451111e-07 4.07391185942275e-07 TLR2/ITGAM/PSMB10/CD300LF/HAVCR2/PSME2/CTSS/HCK/CD14/ITGB2/BTK/CLEC4A/CD300A/TLR4/FCER1G/NR1H3/LGMN/LY96/CD86/PSMB9/PSME1/PLCG2/IRF1 23 BP GO:0002664 regulation of T cell tolerance induction 6/363 11/17381 3.36831136357303e-08 5.67773077532204e-07 4.13422127077989e-07 LILRB2/IDO1/FOXP3/CD3E/IL2RA/CD86 6 BP GO:0002440 production of molecular mediator of immune response 20/363 218/17381 3.37460828486232e-08 5.67773077532204e-07 4.13422127077989e-07 CD96/LILRB1/TLR2/CD74/POU2F2/PTPRC/HLA-DQB1/BATF/FOXP3/BTK/HLA-E/IL7R/TLR4/FCER1G/TNFRSF4/JAK3/CD40/TNFSF13B/SLC11A1/SASH3 20 BP GO:0009615 response to virus 24/363 310/17381 3.89781497715453e-08 6.52117584380122e-07 4.74837306501379e-07 CXCL9/APOBEC3C/LILRB1/PTPRC/GBP1/FGR/CD8A/APOBEC3D/FOXP3/SPN/PRF1/RNASE6/CXCL10/APOBEC3G/CD40/IL12RB1/APOBEC3H/CCL5/IL2RA/IL15/CCL4/CD86/CXCR4/IRF1 24 BP GO:0008360 regulation of cell shape 16/363 142/17381 4.69641655818863e-08 7.81336788284119e-07 5.68927851212501e-07 PLXNC1/FGD2/FGR/LST1/SEMA4D/CSF1R/HCK/FMNL1/ITGB2/FGD3/PTK2B/S100B/CCL13/CCL3/CORO1A/PLEKHO1 16 BP GO:0002707 negative regulation of lymphocyte mediated immunity 9/363 37/17381 5.08341196961986e-08 8.41022269195997e-07 6.12387640784615e-07 CD96/LILRB1/PTPRC/HAVCR2/PTPN6/FOXP3/SPN/HLA-E/IL7R 9 BP GO:0046633 alpha-beta T cell proliferation 8/363 27/17381 5.26000522099713e-08 8.6543069326682e-07 6.30160555699569e-07 ZAP70/EBI3/DOCK2/CD3E/HLA-E/RASAL3/IL15/IRF1 8 BP GO:0038093 Fc receptor signaling pathway 21/363 246/17381 5.34984900244824e-08 8.72342271731213e-07 6.35193199168039e-07 WAS/FCGR3A/LCP2/FCGR2A/WIPF1/PSMB10/PSME2/FGR/CD247/VAV1/LAT2/HCK/BTK/CD3G/MYO1G/ELMO1/NCKAP1L/FCER1G/PSMB9/PSME1/PLCG2 21 BP GO:0030101 natural killer cell activation 12/363 76/17381 5.36059891627979e-08 8.72342271731213e-07 6.35193199168039e-07 FLT3LG/HAVCR2/CD2/PIK3CD/ITGB2/SLAMF7/RASGRP1/SLAMF6/CORO1A/ZNF683/IL15/RAB27A 12 BP GO:0045060 negative thymic T cell selection 6/363 12/17381 6.61817397639258e-08 1.07113707074441e-06 7.79944988064572e-07 ZAP70/DOCK2/CD74/SPN/CD3E/CCR7 6 BP GO:0071622 regulation of granulocyte chemotaxis 10/363 50/17381 6.81667645464691e-08 1.09730067469938e-06 7.98995931526181e-07 RAC2/CD74/C3AR1/CSF1/CCR7/NCKAP1L/MPP1/CCL5/CMKLR1/C5AR1 10 BP GO:0051209 release of sequestered calcium ion into cytosol 14/363 112/17381 8.83112391007278e-08 1.40636828899448e-06 1.02404251363636e-06 CXCL9/PTPRC/CLIC2/PTPN6/PTK2B/CXCL11/CXCL10/LCK/CCR7/CCL3/CORO1A/CCR5/TRPM2/PLCG2 14 BP GO:0051283 negative regulation of sequestering of calcium ion 14/363 112/17381 8.83112391007278e-08 1.40636828899448e-06 1.02404251363636e-06 CXCL9/PTPRC/CLIC2/PTPN6/PTK2B/CXCL11/CXCL10/LCK/CCR7/CCL3/CORO1A/CCR5/TRPM2/PLCG2 14 BP GO:0002218 activation of innate immune response 23/363 301/17381 9.55523546212222e-08 1.51358995777659e-06 1.10211562441051e-06 TLR2/ITGAM/PSMB10/CD300LF/HAVCR2/PSME2/CTSS/HCK/CD14/ITGB2/BTK/CLEC4A/CD300A/TLR4/FCER1G/NR1H3/LGMN/LY96/CD86/PSMB9/PSME1/PLCG2/IRF1 23 BP GO:0050848 regulation of calcium-mediated signaling 12/363 80/17381 9.65860637932222e-08 1.52186930146146e-06 1.10814420169333e-06 ZAP70/GBP1/CLIC2/CD8A/CD3E/PTK2B/CD4/CCL3/CMKLR1/CCL4/SLA2/TREM2 12 BP GO:0036336 dendritic cell migration 8/363 29/17381 9.80459489656704e-08 1.53022678494321e-06 1.11422967621611e-06 DOCK8/CCR1/GPR183/CCR7/CCL5/CCR5/TRPM2/CXCR4 8 BP GO:0007229 integrin-mediated signaling pathway 13/363 96/17381 9.81441624997153e-08 1.53022678494321e-06 1.11422967621611e-06 FERMT3/ITGAM/ITGAE/FGR/VAV1/ITGAX/HCK/ITGB7/ITGB2/PTK2B/TYROBP/ITGAL/FCER1G 13 BP GO:0051282 regulation of sequestering of calcium ion 14/363 113/17381 9.89168977406375e-08 1.53424229933135e-06 1.11715356000939e-06 CXCL9/PTPRC/CLIC2/PTPN6/PTK2B/CXCL11/CXCL10/LCK/CCR7/CCL3/CORO1A/CCR5/TRPM2/PLCG2 14 BP GO:0046635 positive regulation of alpha-beta T cell activation 10/363 52/17381 1.01156060927076e-07 1.56084326135146e-06 1.13652296432929e-06 ZAP70/EBI3/FOXP3/CD3E/HLA-E/RASAL3/NCKAP1L/IL12RB1/CD86/SASH3 10 BP GO:0071356 cellular response to tumor necrosis factor 22/363 279/17381 1.05363800534722e-07 1.61738864944538e-06 1.17769630548849e-06 IL18BP/CCL4L1/TNFRSF1B/PSMB10/PSME2/CARD16/CCL3L1/CCL3L3/PTK2B/CD27/CCL13/CASP1/CCL3/TNFRSF4/CD40/XCL2/CCL5/CCL4/TNFSF13B/CCL18/PSMB9/PSME1 22 BP GO:0001771 immunological synapse formation 6/363 13/17381 1.2074857503131e-07 1.80698118815699e-06 1.31574749835757e-06 DOCK2/DOCK8/HAVCR2/PRF1/CCR7/CD6 6 BP GO:0002517 T cell tolerance induction 6/363 13/17381 1.2074857503131e-07 1.80698118815699e-06 1.31574749835757e-06 LILRB2/IDO1/FOXP3/CD3E/IL2RA/CD86 6 BP GO:0035723 interleukin-15-mediated signaling pathway 6/363 13/17381 1.2074857503131e-07 1.80698118815699e-06 1.31574749835757e-06 IL2RB/CD4/JAK3/IL15/IL2RG/IL15RA 6 BP GO:0043383 negative T cell selection 6/363 13/17381 1.2074857503131e-07 1.80698118815699e-06 1.31574749835757e-06 ZAP70/DOCK2/CD74/SPN/CD3E/CCR7 6 BP GO:0071350 cellular response to interleukin-15 6/363 13/17381 1.2074857503131e-07 1.80698118815699e-06 1.31574749835757e-06 IL2RB/CD4/JAK3/IL15/IL2RG/IL15RA 6 BP GO:0031663 lipopolysaccharide-mediated signaling pathway 10/363 53/17381 1.22388402894562e-07 1.82236331910003e-06 1.32694794717262e-06 LY86/TLR2/CARD16/HCK/CD14/TLR4/CCL3/CCL5/LY96/CD6 10 BP GO:0031341 regulation of cell killing 11/363 67/17381 1.27957134972865e-07 1.89580272611539e-06 1.38042261348051e-06 LILRB1/LAG3/PTPRC/HAVCR2/VAV1/PRF1/RASGRP1/HLA-E/IL7R/SLAMF6/IL12RB1 11 BP GO:0002820 negative regulation of adaptive immune response 9/363 41/17381 1.32984119742548e-07 1.96052826036291e-06 1.42755230156148e-06 LILRB1/PTPRC/HAVCR2/PTPN6/FOXP3/SPN/SAMSN1/IL7R/JAK3 9 BP GO:0051208 sequestering of calcium ion 14/363 116/17381 1.37989518751338e-07 2.02429944256889e-06 1.47398708129508e-06 CXCL9/PTPRC/CLIC2/PTPN6/PTK2B/CXCL11/CXCL10/LCK/CCR7/CCL3/CORO1A/CCR5/TRPM2/PLCG2 14 BP GO:0001776 leukocyte homeostasis 12/363 83/17381 1.46782005248553e-07 2.12670084952771e-06 1.54855033403806e-06 DOCK10/SIT1/CD74/PIK3CD/FOXP3/GPR183/NCKAP1L/FCER1G/JAK3/CORO1A/IL2RA/TNFSF13B 12 BP GO:0050854 regulation of antigen receptor-mediated signaling pathway 10/363 54/17381 1.47442712340649e-07 2.12670084952771e-06 1.54855033403806e-06 NFAM1/PTPRC/GBP1/PTPN6/GCSAM/LPXN/CD300A/LCK/CCR7/LILRB4 10 BP GO:0070228 regulation of lymphocyte apoptotic process 10/363 54/17381 1.47442712340649e-07 2.12670084952771e-06 1.54855033403806e-06 CD74/DOCK8/PDCD1/IDO1/BTK/CD3G/CD27/JAK3/CCL5/CD274 10 BP GO:0045061 thymic T cell selection 7/363 21/17381 1.47826419023585e-07 2.12670084952771e-06 1.54855033403806e-06 ZAP70/DOCK2/CD74/CD3D/SPN/CD3E/CCR7 7 BP GO:0002224 toll-like receptor signaling pathway 15/363 135/17381 1.49274800829699e-07 2.13721325418674e-06 1.55620490743512e-06 TLR2/ITGAM/CD300LF/HAVCR2/CTSS/CD14/ITGB2/BTK/CD300A/TLR4/NR1H3/LGMN/LY96/CD86/IRF1 15 BP GO:0071675 regulation of mononuclear cell migration 9/363 42/17381 1.66162915583503e-07 2.36762278759651e-06 1.72397686276513e-06 C3AR1/AIF1/CCR1/CSF1/CXCL10/PLA2G7/CCL5/CMKLR1/C5AR1 9 BP GO:0070227 lymphocyte apoptotic process 11/363 69/17381 1.74950994207098e-07 2.47797537475926e-06 1.80432974161538e-06 CD74/DOCK8/PDCD1/IDO1/BTK/CD3G/CD27/JAK3/CCL5/CD274/IL2RA 11 BP GO:0032845 negative regulation of homeostatic process 18/363 197/17381 1.75571794517865e-07 2.47797537475926e-06 1.80432974161538e-06 CXCL9/CD74/PTPRC/CLIC2/PTPN6/INPP5D/CD38/PTK2B/CXCL11/CXCL10/LCK/CCR7/CCL3/FCER1G/CORO1A/CCR5/TRPM2/PLCG2 18 BP GO:0001910 regulation of leukocyte mediated cytotoxicity 10/363 55/17381 1.76895371095508e-07 2.48487931661521e-06 1.80935682451215e-06 LILRB1/LAG3/PTPRC/HAVCR2/VAV1/RASGRP1/HLA-E/IL7R/SLAMF6/IL12RB1 10 BP GO:0070672 response to interleukin-15 6/363 14/17381 2.07597043849935e-07 2.90246007786435e-06 2.11341690304357e-06 IL2RB/CD4/JAK3/IL15/IL2RG/IL15RA 6 BP GO:0043368 positive T cell selection 8/363 32/17381 2.27466627657521e-07 3.16540008020607e-06 2.30487581394242e-06 ZAP70/DOCK2/CD74/CD3D/BATF/FOXP3/SLAMF6/IL12RB1 8 BP GO:0006959 humoral immune response 23/363 321/17381 3.03064785220903e-07 4.19779967622256e-06 3.05661423527569e-06 LYZ/LY86/EBI3/SERPING1/POU2F2/PSMB10/HLA-DQB1/PDCD1/GNLY/PTPN6/C3AR1/C1QA/RNASE6/HLA-E/GPR183/CCL13/VSIG4/CCR7/C1QC/C5AR1/SLC11A1/C1QB/TREM2 23 BP GO:0051607 defense response to virus 19/363 227/17381 3.1581017000474e-07 4.35408651052832e-06 3.17041398737702e-06 CXCL9/APOBEC3C/LILRB1/PTPRC/GBP1/CD8A/APOBEC3D/SPN/PRF1/RNASE6/CXCL10/APOBEC3G/CD40/IL12RB1/APOBEC3H/IL2RA/IL15/CD86/IRF1 19 BP GO:0032623 interleukin-2 production 10/363 59/17381 3.52816240227381e-07 4.8418744857011e-06 3.52559522128743e-06 LAG3/HAVCR2/GBP1/FOXP3/CD3E/VSIG4/CD4/CD86/SLC11A1/SASH3 10 BP GO:0002279 mast cell activation involved in immune response 9/363 46/17381 3.81401998938254e-07 5.12962493558609e-06 3.73511977919032e-06 RAC2/MILR1/FGR/LAT2/PIK3CD/BTK/RASGRP1/CD300A/FCER1G 9 BP GO:0043303 mast cell degranulation 9/363 46/17381 3.81401998938254e-07 5.12962493558609e-06 3.73511977919032e-06 RAC2/MILR1/FGR/LAT2/PIK3CD/BTK/RASGRP1/CD300A/FCER1G 9 BP GO:2000107 negative regulation of leukocyte apoptotic process 9/363 46/17381 3.81401998938254e-07 5.12962493558609e-06 3.73511977919032e-06 LILRB1/CD74/DOCK8/IDO1/CD27/CCR7/FCER1G/JAK3/CCL5 9 BP GO:2000401 regulation of lymphocyte migration 9/363 46/17381 3.81401998938254e-07 5.12962493558609e-06 3.73511977919032e-06 DOCK8/STK10/GCSAM/AIF1/PTK2B/CXCL10/CCL3/CCL5/CCL4 9 BP GO:0060402 calcium ion transport into cytosol 15/363 145/17381 3.8239648613167e-07 5.12962493558609e-06 3.73511977919032e-06 CXCL9/PTPRC/CLIC2/PTPN6/PTK2B/CXCL11/CXCL10/LCK/CD4/CCR7/CCL3/CORO1A/CCR5/TRPM2/PLCG2 15 BP GO:0002698 negative regulation of immune effector process 13/363 108/17381 3.99614558638952e-07 5.33655675168968e-06 3.88579651072099e-06 CD96/LILRB1/SERPING1/PTPRC/HAVCR2/PTPN6/FOXP3/SPN/HLA-E/CD300A/IL7R/JAK3/IL2RA 13 BP GO:0046632 alpha-beta T cell differentiation 12/363 92/17381 4.64586417213886e-07 6.17651049313818e-06 4.4974061064878e-06 ZAP70/BATF/FOXP3/GPR183/NCKAP1L/SLAMF6/JAK3/IL12RB1/ZNF683/CD86/SASH3/IRF1 12 BP GO:0097553 calcium ion transmembrane import into cytosol 14/363 128/17381 4.72801792709692e-07 6.25779439417539e-06 4.5565927157051e-06 CXCL9/PTPRC/CLIC2/PTPN6/PTK2B/CXCL11/CXCL10/LCK/CCR7/CCL3/CORO1A/CCR5/TRPM2/PLCG2 14 BP GO:0002448 mast cell mediated immunity 9/363 48/17381 5.59610463873756e-07 7.37398213015949e-06 5.36934119972025e-06 RAC2/MILR1/FGR/LAT2/PIK3CD/BTK/RASGRP1/CD300A/FCER1G 9 BP GO:0002407 dendritic cell chemotaxis 7/363 25/17381 5.68608664103533e-07 7.45954450088247e-06 5.43164316277894e-06 CCR1/GPR183/CCR7/CCL5/CCR5/TRPM2/CXCR4 7 BP GO:0002715 regulation of natural killer cell mediated immunity 8/363 36/17381 6.08355315439662e-07 7.91127567414547e-06 5.76056975318641e-06 CD96/LILRB1/LAG3/HAVCR2/VAV1/RASGRP1/HLA-E/SLAMF6 8 BP GO:0002755 MyD88-dependent toll-like receptor signaling pathway 8/363 36/17381 6.08355315439662e-07 7.91127567414547e-06 5.76056975318641e-06 TLR2/CD300LF/CD14/BTK/CD300A/TLR4/LY96/IRF1 8 BP GO:0002708 positive regulation of lymphocyte mediated immunity 11/363 78/17381 6.30913548600568e-07 8.16895890318474e-06 5.94820096163464e-06 LAG3/VAV1/FOXP3/BTK/RASGRP1/HLA-E/SLAMF6/FCER1G/CD40/IL12RB1/SASH3 11 BP GO:0050729 positive regulation of inflammatory response 13/363 114/17381 7.51297810488929e-07 9.68556224950662e-06 7.0525107751524e-06 GBP5/TLR2/IDO1/GPSM3/BTK/TLR4/CCR7/CCL3/FCER1G/ETS1/PLA2G7/IL15/CD6 13 BP GO:0045577 regulation of B cell differentiation 7/363 26/17381 7.64207596409753e-07 9.80952681943209e-06 7.14277517515468e-06 NFAM1/PTPN6/INPP5D/BTK/CD27/NCKAP1L/IKZF3 7 BP GO:0031348 negative regulation of defense response 16/363 174/17381 7.82143236041689e-07 9.99666333447274e-06 7.27903802234416e-06 CD96/NLRC3/LILRB1/SERPING1/TRAFD1/TNFRSF1B/HAVCR2/FOXP3/SPN/HLA-E/TNFAIP8L2/APOE/ETS1/NR1H3/IL2RA/ACP5 16 BP GO:0032693 negative regulation of interleukin-10 production 6/363 17/17381 8.11269263564782e-07 1.03246148157945e-05 7.51783483105466e-06 LILRB1/IDO1/PDCD1LG2/FOXP3/JAK3/CD274 6 BP GO:0042035 regulation of cytokine biosynthetic process 12/363 97/17381 8.31238067392621e-07 1.05337317646605e-05 7.67010265992743e-06 EBI3/LILRB1/LAG3/CYBB/INPP5D/FOXP3/SPN/CD3E/TLR4/CD4/CD86/IRF1 12 BP GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 8/363 38/17381 9.47957125235868e-07 1.19619335548831e-05 8.7100431667524e-06 LILRB1/PTPRC/HAVCR2/PTPN6/FOXP3/SPN/IL7R/JAK3 8 BP GO:0038094 Fc-gamma receptor signaling pathway 14/363 136/17381 9.939228444463e-07 1.2489038948359e-05 9.09385325142962e-06 WAS/FCGR3A/FCGR2A/WIPF1/FGR/CD247/VAV1/HCK/CD3G/MYO1G/ELMO1/NCKAP1L/FCER1G/PLCG2 14 BP GO:0050871 positive regulation of B cell activation 13/363 117/17381 1.01441946745246e-06 1.26930301431657e-05 9.24238877908924e-06 CD74/PTPRC/INPP5D/CD38/BTK/GPR183/CD27/TLR4/NCKAP1L/TNFRSF4/CD40/TNFSF13B/SASH3 13 BP GO:0006911 phagocytosis, engulfment 11/363 82/17381 1.05415852368339e-06 1.31350798474022e-05 9.56426583918866e-06 BIN2/ITGAM/ARHGAP25/MSR1/AIF1/ITGB2/CD300A/ELMO1/NCKAP1L/FCER1G/TREM2 11 BP GO:0060401 cytosolic calcium ion transport 15/363 157/17381 1.06611720827013e-06 1.32287376926185e-05 9.63246249577394e-06 CXCL9/PTPRC/CLIC2/PTPN6/PTK2B/CXCL11/CXCL10/LCK/CD4/CCR7/CCL3/CORO1A/CCR5/TRPM2/PLCG2 15 BP GO:0002431 Fc receptor mediated stimulatory signaling pathway 14/363 137/17381 1.08640251737251e-06 1.34245091150844e-05 9.77501282283198e-06 WAS/FCGR3A/FCGR2A/WIPF1/FGR/CD247/VAV1/HCK/CD3G/MYO1G/ELMO1/NCKAP1L/FCER1G/PLCG2 14 BP GO:0032663 regulation of interleukin-2 production 9/363 52/17381 1.14052118509254e-06 1.39772513959077e-05 1.01774903239793e-05 LAG3/HAVCR2/GBP1/FOXP3/CD3E/VSIG4/CD4/CD86/SASH3 9 BP GO:0038083 peptidyl-tyrosine autophosphorylation 9/363 52/17381 1.14052118509254e-06 1.39772513959077e-05 1.01774903239793e-05 SLA/ZAP70/FGR/HCK/BTK/PTK2B/LCK/JAK3/SLA2 9 BP GO:0030168 platelet activation 15/363 158/17381 1.15592615415381e-06 1.41079839634019e-05 1.0272682819486e-05 RAC2/FERMT3/LCP2/PTPN6/VAV1/PIK3CD/GNG2/LCK/TLR4/APOE/PIK3R5/FCER1G/CD40/RHOG/PLCG2 15 BP GO:1905517 macrophage migration 8/363 39/17381 1.17105340275098e-06 1.42342736056834e-05 1.03646402133922e-05 MCOLN2/C3AR1/PTK2B/CSF1/CCL3/CCL5/CMKLR1/C5AR1 8 BP GO:0018108 peptidyl-tyrosine phosphorylation 24/363 375/17381 1.28302165364044e-06 1.55318637582977e-05 1.13094762794151e-05 SLA/ZAP70/CD74/FGR/PTPN6/SEMA4D/CSF1R/HCK/CD3E/ITGB2/BTK/PTK2B/SAMSN1/CD300A/LCK/CD4/SOCS1/JAK3/CD40/IL12RB1/CCL5/IL15/SLA2/TREM2 24 BP GO:0045589 regulation of regulatory T cell differentiation 7/363 28/17381 1.32692456823491e-06 1.5998305118233e-05 1.16491140445937e-05 CTLA4/LILRB2/FOXP3/SOCS1/LILRB4/IL2RA/IRF1 7 BP GO:0033077 T cell differentiation in thymus 10/363 68/17381 1.3819347191386e-06 1.65277172433524e-05 1.20346037684444e-05 ZAP70/DOCK2/CD74/CD3D/FOXP3/SPN/CD3E/RASGRP1/IL7R/CCR7 10 BP GO:0050764 regulation of phagocytosis 10/363 68/17381 1.3819347191386e-06 1.65277172433524e-05 1.20346037684444e-05 DOCK2/TLR2/CD300LF/FGR/HCK/CD300A/NCKAP1L/FCER1G/RAB27A/SLC11A1 10 BP GO:0018212 peptidyl-tyrosine modification 24/363 378/17381 1.47621847820113e-06 1.75847145123319e-05 1.28042529056604e-05 SLA/ZAP70/CD74/FGR/PTPN6/SEMA4D/CSF1R/HCK/CD3E/ITGB2/BTK/PTK2B/SAMSN1/CD300A/LCK/CD4/SOCS1/JAK3/CD40/IL12RB1/CCL5/IL15/SLA2/TREM2 24 BP GO:0001773 myeloid dendritic cell activation 7/363 29/17381 1.71793140163875e-06 2.03015861669849e-05 1.47825341995649e-05 SPI1/FLT3LG/DOCK2/HAVCR2/BATF/CD2/CD86 7 BP GO:2000403 positive regulation of lymphocyte migration 7/363 29/17381 1.71793140163875e-06 2.03015861669849e-05 1.47825341995649e-05 DOCK8/AIF1/PTK2B/CXCL10/CCL3/CCL5/CCL4 7 BP GO:0097028 dendritic cell differentiation 8/363 41/17381 1.75360473912886e-06 2.0641244715912e-05 1.50298554716266e-05 SPI1/LILRB1/LILRB2/BATF/CCR7/TRPM2/CD86/TREM2 8 BP GO:0002532 production of molecular mediator involved in inflammatory response 9/363 55/17381 1.86533179565595e-06 2.17841493626017e-05 1.58620577876213e-05 GBP5/CD96/NLRC3/IDO1/GPSM3/BTK/TLR4/FCER1G/CD6 9 BP GO:0002709 regulation of T cell mediated immunity 9/363 55/17381 1.86533179565595e-06 2.17841493626017e-05 1.58620577876213e-05 WAS/LILRB1/PTPRC/FOXP3/SPN/HLA-E/IL7R/IL12RB1/SASH3 9 BP GO:0002367 cytokine production involved in immune response 11/363 87/17381 1.92088358148582e-06 2.2345278537753e-05 1.62706421787039e-05 CD96/LILRB1/TLR2/CD74/FOXP3/BTK/TLR4/FCER1G/JAK3/SLC11A1/SASH3 11 BP GO:0030316 osteoclast differentiation 11/363 88/17381 2.154806569454e-06 2.49689259293152e-05 1.81810425274431e-05 LILRB1/CSF1R/INPP5D/CCR1/CSF1/GPR183/TYROBP/TLR4/CCL3/LILRB4/SNX10 11 BP GO:0045066 regulatory T cell differentiation 7/363 30/17381 2.20082527197426e-06 2.53052419302677e-05 1.84259299340255e-05 CTLA4/LILRB2/FOXP3/SOCS1/LILRB4/IL2RA/IRF1 7 BP GO:0045730 respiratory burst 7/363 30/17381 2.20082527197426e-06 2.53052419302677e-05 1.84259299340255e-05 RAC2/NCF4/CYBB/PIK3CD/HCK/SLC11A1/CD52 7 BP GO:0001779 natural killer cell differentiation 6/363 20/17381 2.40941148893675e-06 2.7597028515591e-05 2.00946869117802e-05 FLT3LG/PIK3CD/RASGRP1/SLAMF6/ZNF683/IL15 6 BP GO:0042089 cytokine biosynthetic process 12/363 108/17381 2.6470539819653e-06 3.02027845145312e-05 2.19920597009418e-05 EBI3/LILRB1/LAG3/CYBB/INPP5D/FOXP3/SPN/CD3E/TLR4/CD4/CD86/IRF1 12 BP GO:0032689 negative regulation of interferon-gamma production 7/363 31/17381 2.79205786133165e-06 3.17356805765101e-05 2.31082330025841e-05 CD96/LILRB1/HAVCR2/PDCD1LG2/FOXP3/TLR4/CD274 7 BP GO:0002791 regulation of peptide secretion 26/363 448/17381 2.85498654169007e-06 3.23275662401256e-05 2.35392126311049e-05 CLEC5A/LILRB1/TLR2/CD74/HAVCR2/CARD16/GBP1/CD2/FGR/CSF1R/SRGN/FOXP3/CD38/CD14/RASGRP1/HLA-E/TLR4/CASP1/CCR7/CCL3/SOCS1/TNFRSF4/CD40/CCL5/NR1H3/CD274 26 BP GO:0050708 regulation of protein secretion 25/363 421/17381 2.96857096496237e-06 3.34863800517346e-05 2.43829991539971e-05 CLEC5A/LILRB1/TLR2/HAVCR2/CARD16/GBP1/CD2/FGR/CSF1R/SRGN/FOXP3/CD38/CD14/RASGRP1/HLA-E/TLR4/CASP1/CCR7/CCL3/SOCS1/TNFRSF4/CD40/CCL5/NR1H3/CD274 25 BP GO:0099024 plasma membrane invagination 11/363 91/17381 3.0131577265399e-06 3.37337733444955e-05 2.4563137778679e-05 BIN2/ITGAM/ARHGAP25/MSR1/AIF1/ITGB2/CD300A/ELMO1/NCKAP1L/FCER1G/TREM2 11 BP GO:1902106 negative regulation of leukocyte differentiation 11/363 91/17381 3.0131577265399e-06 3.37337733444955e-05 2.4563137778679e-05 LILRB1/CD74/CTLA4/INPP5D/FOXP3/TLR4/CCL3/JAK3/C1QC/LILRB4/IRF1 11 BP GO:0042107 cytokine metabolic process 12/363 110/17381 3.21623879580753e-06 3.58725061195312e-05 2.61204491202977e-05 EBI3/LILRB1/LAG3/CYBB/INPP5D/FOXP3/SPN/CD3E/TLR4/CD4/CD86/IRF1 12 BP GO:0032735 positive regulation of interleukin-12 production 7/363 32/17381 3.5101434067604e-06 3.90045039751211e-05 2.84010032125939e-05 IRF8/TLR2/IDO1/TLR4/CCR7/CD40/IRF1 7 BP GO:0002761 regulation of myeloid leukocyte differentiation 12/363 111/17381 3.53931547310098e-06 3.91824590293484e-05 2.85305806088359e-05 LILRB1/CD74/EVI2B/INPP5D/CCR1/CSF1/TYROBP/TLR4/CD4/CCL3/C1QC/LILRB4 12 BP GO:0045824 negative regulation of innate immune response 8/363 45/17381 3.67818350184165e-06 4.05690017351276e-05 2.954018718828e-05 CD96/NLRC3/LILRB1/SERPING1/TRAFD1/HAVCR2/HLA-E/NR1H3 8 BP GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis 13/363 132/17381 3.98392453379344e-06 4.36181149324885e-05 3.17603890851954e-05 WAS/FCGR3A/FCGR2A/WIPF1/FGR/CD247/VAV1/HCK/CD3G/MYO1G/ELMO1/NCKAP1L/PLCG2 13 BP GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis 13/363 132/17381 3.98392453379344e-06 4.36181149324885e-05 3.17603890851954e-05 WAS/FCGR3A/FCGR2A/WIPF1/FGR/CD247/VAV1/HCK/CD3G/MYO1G/ELMO1/NCKAP1L/PLCG2 13 BP GO:0019724 B cell mediated immunity 16/363 197/17381 4.01985134152281e-06 4.38502465020327e-05 3.19294149355581e-05 CD74/SERPING1/POU2F2/HLA-DQB1/BATF/PTPN6/INPP5D/FOXP3/BTK/C1QA/CD27/FCER1G/CD40/C1QC/SLA2/C1QB 16 BP GO:0048246 macrophage chemotaxis 7/363 33/17381 4.3758055498923e-06 4.73859961002882e-05 3.45039595513039e-05 C3AR1/PTK2B/CSF1/CCL3/CCL5/CMKLR1/C5AR1 7 BP GO:0070232 regulation of T cell apoptotic process 7/363 33/17381 4.3758055498923e-06 4.73859961002882e-05 3.45039595513039e-05 DOCK8/PDCD1/IDO1/CD27/JAK3/CCL5/CD274 7 BP GO:0002335 mature B cell differentiation 6/363 22/17381 4.47696076721654e-06 4.79582344056506e-05 3.49206330195611e-05 DOCK10/POU2F2/PTK2B/GPR183/MFNG/PLCG2 6 BP GO:0010758 regulation of macrophage chemotaxis 6/363 22/17381 4.47696076721654e-06 4.79582344056506e-05 3.49206330195611e-05 C3AR1/PTK2B/CSF1/CCL5/CMKLR1/C5AR1 6 BP GO:0032753 positive regulation of interleukin-4 production 6/363 22/17381 4.47696076721654e-06 4.79582344056506e-05 3.49206330195611e-05 HAVCR2/FOXP3/CD3E/HLA-E/CD86/SASH3 6 BP GO:0050715 positive regulation of cytokine secretion 12/363 115/17381 5.13570654644385e-06 5.48176849294257e-05 3.99153196969414e-05 CLEC5A/TLR2/HAVCR2/CD2/FGR/CSF1R/CD14/RASGRP1/TLR4/CASP1/CCL3/CD274 12 BP GO:0042269 regulation of natural killer cell mediated cytotoxicity 7/363 34/17381 5.41212509039048e-06 5.73569698191561e-05 4.1764291763268e-05 LILRB1/LAG3/HAVCR2/VAV1/RASGRP1/HLA-E/SLAMF6 7 BP GO:0090022 regulation of neutrophil chemotaxis 7/363 34/17381 5.41212509039048e-06 5.73569698191561e-05 4.1764291763268e-05 RAC2/CD74/C3AR1/CCR7/NCKAP1L/MPP1/C5AR1 7 BP GO:0007599 hemostasis 22/363 353/17381 5.47602070225186e-06 5.78283320968299e-05 4.21075126787564e-05 WAS/RAC2/DOCK8/FERMT3/SERPING1/LCP2/PTPN6/VAV1/PIK3CD/GNG2/FLI1/LCK/TLR4/APOE/PIK3R5/FCER1G/CD40/MICAL1/RAB27A/RHOG/PLCG2/IRF1 22 BP GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 10/363 79/17381 5.5863398682126e-06 5.87848767757495e-05 4.2804017587941e-05 FOXP3/BTK/HLA-E/CD4/FCER1G/CD40/IL12RB1/TNFSF13B/SLC11A1/SASH3 10 BP GO:0051924 regulation of calcium ion transport 17/363 226/17381 5.67930887308273e-06 5.95527529015506e-05 4.33631441013729e-05 CXCL9/LILRB1/LILRB2/CLIC2/PTPN6/CCR1/PTK2B/CXCL11/CXCL10/CD4/IL16/CCL3/TRPV2/CORO1A/CCL5/CCL4/PLCG2 17 BP GO:0051235 maintenance of location 20/363 302/17381 5.98848266042359e-06 6.24162228790779e-05 4.54481704891664e-05 CXCL9/PTPRC/CLIC2/MSR1/PTPN6/SRGN/PTK2B/CXCL11/CD27/CXCL10/LCK/CD4/CCR7/CCL3/APOE/CORO1A/CCR5/NR1H3/TRPM2/PLCG2 20 BP GO:0002260 lymphocyte homeostasis 9/363 63/17381 5.99430481645947e-06 6.24162228790779e-05 4.54481704891664e-05 DOCK10/SIT1/CD74/FOXP3/NCKAP1L/JAK3/CORO1A/IL2RA/TNFSF13B 9 BP GO:0070231 T cell apoptotic process 8/363 48/17381 6.09701245951378e-06 6.32644707471499e-05 4.60658194263649e-05 DOCK8/PDCD1/IDO1/CD27/JAK3/CCL5/CD274/IL2RA 8 BP GO:0002700 regulation of production of molecular mediator of immune response 12/363 117/17381 6.14888485477002e-06 6.33611733477686e-05 4.61362331117328e-05 CD96/LILRB1/CD74/FOXP3/BTK/HLA-E/TLR4/FCER1G/TNFRSF4/JAK3/CD40/SASH3 12 BP GO:0070555 response to interleukin-1 12/363 117/17381 6.14888485477002e-06 6.33611733477686e-05 4.61362331117328e-05 CCL4L1/CCL3L1/CCL3L3/CD38/CCL13/CCL3/ETS1/CD40/XCL2/CCL5/CCL4/CCL18 12 BP GO:0002221 pattern recognition receptor signaling pathway 15/363 182/17381 6.72909730654165e-06 6.89323910304089e-05 5.01928972191306e-05 TLR2/ITGAM/CD300LF/HAVCR2/CTSS/CD14/ITGB2/BTK/CD300A/TLR4/NR1H3/LGMN/LY96/CD86/IRF1 15 BP GO:0043900 regulation of multi-organism process 23/363 385/17381 6.73583807583915e-06 6.89323910304089e-05 5.01928972191306e-05 LY86/IRF8/APOBEC3C/LILRB1/CD74/HAVCR2/CARD16/APOBEC3D/SPN/LHFPL2/PRF1/ARHGDIB/APOBEC3G/CD4/CCL3/APOE/IL12RB1/APOBEC3H/CCL5/IL2RA/IL15/CCL4/LY96 23 BP GO:0010324 membrane invagination 11/363 99/17381 6.91592608478787e-06 7.05329721934872e-05 5.13583552078696e-05 BIN2/ITGAM/ARHGAP25/MSR1/AIF1/ITGB2/CD300A/ELMO1/NCKAP1L/FCER1G/TREM2 11 BP GO:0032844 regulation of homeostatic process 26/363 473/17381 7.57654286330152e-06 7.70066370201772e-05 5.60721332796879e-05 SPI1/CXCL9/CD74/PTPRC/CLIC2/PTPN6/CSF1R/INPP5D/PIK3CD/CD38/PTK2B/CXCL11/CXCL10/LCK/CD4/CCR7/NCKAP1L/CCL3/FCER1G/ETS1/CORO1A/CCR5/NR1H3/IL2RA/TRPM2/PLCG2 26 BP GO:0046640 regulation of alpha-beta T cell proliferation 6/363 24/17381 7.79566595407881e-06 7.87846253401319e-05 5.73667697149877e-05 ZAP70/EBI3/CD3E/HLA-E/RASAL3/IRF1 6 BP GO:0042116 macrophage activation 9/363 65/17381 7.80438699642005e-06 7.87846253401319e-05 5.73667697149877e-05 TLR2/CD74/ITGAM/HAVCR2/AIF1/TYROBP/TLR4/NR1H3/SLC11A1 9 BP GO:1903707 negative regulation of hemopoiesis 13/363 141/17381 8.25803871724678e-06 8.30825652025707e-05 6.0496300702448e-05 GPR171/LILRB1/CD74/CTLA4/INPP5D/FOXP3/PTK2B/TLR4/CCL3/JAK3/C1QC/LILRB4/IRF1 13 BP GO:0002821 positive regulation of adaptive immune response 10/363 83/17381 8.75929276446701e-06 8.78288681905143e-05 6.39523058472516e-05 FOXP3/BTK/HLA-E/CD4/FCER1G/CD40/IL12RB1/TNFSF13B/SLC11A1/SASH3 10 BP GO:0043367 CD4-positive, alpha-beta T cell differentiation 9/363 66/17381 8.87234934101495e-06 8.86639474414179e-05 6.45603660985192e-05 BATF/FOXP3/GPR183/NCKAP1L/SLAMF6/JAK3/IL12RB1/CD86/SASH3 9 BP GO:0001911 negative regulation of leukocyte mediated cytotoxicity 5/363 15/17381 9.769972334872e-06 9.67781225423339e-05 7.04686764120066e-05 LILRB1/PTPRC/HAVCR2/HLA-E/IL7R 5 BP GO:0010759 positive regulation of macrophage chemotaxis 5/363 15/17381 9.769972334872e-06 9.67781225423339e-05 7.04686764120066e-05 C3AR1/CSF1/CCL5/CMKLR1/C5AR1 5 BP GO:0002534 cytokine production involved in inflammatory response 7/363 37/17381 9.81430255466247e-06 9.67781225423339e-05 7.04686764120066e-05 GBP5/CD96/NLRC3/IDO1/GPSM3/TLR4/CD6 7 BP GO:1902622 regulation of neutrophil migration 7/363 37/17381 9.81430255466247e-06 9.67781225423339e-05 7.04686764120066e-05 RAC2/CD74/C3AR1/CCR7/NCKAP1L/MPP1/C5AR1 7 BP GO:0002312 B cell activation involved in immune response 9/363 67/17381 1.00627710558531e-05 9.85754348826662e-05 7.17773835701433e-05 DOCK10/BATF/FOXP3/PTK2B/GPR183/TLR4/CD40/MFNG/PLCG2 9 BP GO:0002718 regulation of cytokine production involved in immune response 9/363 67/17381 1.00627710558531e-05 9.85754348826662e-05 7.17773835701433e-05 CD96/LILRB1/CD74/FOXP3/BTK/TLR4/FCER1G/JAK3/SASH3 9 BP GO:0032418 lysosome localization 9/363 68/17381 1.13869664292503e-05 0.000111181593528876 8.09565171501485e-05 RAC2/MILR1/FGR/LAT2/PIK3CD/BTK/RASGRP1/CD300A/FCER1G 9 BP GO:0030100 regulation of endocytosis 16/363 214/17381 1.15367714120713e-05 0.000112276160997217 8.17535229063187e-05 LILRB1/DOCK2/TLR2/APOC1/CD300LF/FGR/HCK/CD14/CD300A/NCKAP1L/APOE/FCER1G/NR1H3/RAB27A/SLC11A1/PLCG2 16 BP GO:0050850 positive regulation of calcium-mediated signaling 7/363 38/17381 1.18163805548556e-05 0.000114622740365994 8.34621770718416e-05 ZAP70/CD8A/CD3E/CD4/CCL3/CCL4/TREM2 7 BP GO:1905521 regulation of macrophage migration 6/363 26/17381 1.28720006646326e-05 0.000124457201231415 9.06231078918082e-05 C3AR1/PTK2B/CSF1/CCL5/CMKLR1/C5AR1 6 BP GO:0030889 negative regulation of B cell proliferation 5/363 16/17381 1.39679969894147e-05 0.000133599399109546 9.72799696601975e-05 CTLA4/MNDA/INPP5D/BTK/CD300A 5 BP GO:0032695 negative regulation of interleukin-12 production 5/363 16/17381 1.39679969894147e-05 0.000133599399109546 9.72799696601975e-05 LILRB1/JAK3/CMKLR1/TIGIT/ACP5 5 BP GO:1905523 positive regulation of macrophage migration 5/363 16/17381 1.39679969894147e-05 0.000133599399109546 9.72799696601975e-05 C3AR1/CSF1/CCL5/CMKLR1/C5AR1 5 BP GO:0045637 regulation of myeloid cell differentiation 17/363 242/17381 1.39969820423702e-05 0.000133599399109546 9.72799696601975e-05 SPI1/GPR171/LILRB1/CD74/EVI2B/INPP5D/CCR1/PTK2B/CSF1/TYROBP/TLR4/CD4/NCKAP1L/CCL3/ETS1/C1QC/LILRB4 17 BP GO:0007596 blood coagulation 21/363 348/17381 1.45953843564855e-05 0.000138865989180875 0.000101114820159274 WAS/RAC2/DOCK8/FERMT3/SERPING1/LCP2/PTPN6/VAV1/PIK3CD/GNG2/LCK/TLR4/APOE/PIK3R5/FCER1G/CD40/MICAL1/RAB27A/RHOG/PLCG2/IRF1 21 BP GO:0016064 immunoglobulin mediated immune response 15/363 195/17381 1.54402222198549e-05 0.000146436247677478 0.000106627079359374 CD74/SERPING1/POU2F2/HLA-DQB1/BATF/PTPN6/INPP5D/FOXP3/BTK/C1QA/CD27/FCER1G/CD40/C1QC/C1QB 15 BP GO:0032673 regulation of interleukin-4 production 6/363 27/17381 1.62602093582761e-05 0.00015372350307602 0.000111933270770422 HAVCR2/FOXP3/CD3E/HLA-E/CD86/SASH3 6 BP GO:0042088 T-helper 1 type immune response 7/363 40/17381 1.68406100667675e-05 0.000157708606222747 0.000114835010716786 IL18BP/EBI3/HAVCR2/TLR4/JAK3/IL12RB1/SLC11A1 7 BP GO:0098760 response to interleukin-7 7/363 40/17381 1.68406100667675e-05 0.000157708606222747 0.000114835010716786 BTK/PTK2B/IL7R/LCK/SOCS1/JAK3/IL2RG 7 BP GO:0098761 cellular response to interleukin-7 7/363 40/17381 1.68406100667675e-05 0.000157708606222747 0.000114835010716786 BTK/PTK2B/IL7R/LCK/SOCS1/JAK3/IL2RG 7 BP GO:0006816 calcium ion transport 23/363 408/17381 1.71708865291702e-05 0.000160297492425921 0.000116720099818811 MCOLN2/CXCL9/LILRB1/LILRB2/PTPRC/CLIC2/PTPN6/CCR1/PTK2B/CXCL11/CXCL10/LCK/CD4/CCR7/IL16/CCL3/TRPV2/CORO1A/CCL5/CCR5/TRPM2/CCL4/PLCG2 23 BP GO:0050817 coagulation 21/363 354/17381 1.88479728719222e-05 0.000175403947539326 0.000127719816171578 WAS/RAC2/DOCK8/FERMT3/SERPING1/LCP2/PTPN6/VAV1/PIK3CD/GNG2/LCK/TLR4/APOE/PIK3R5/FCER1G/CD40/MICAL1/RAB27A/RHOG/PLCG2/IRF1 21 BP GO:0046637 regulation of alpha-beta T cell differentiation 8/363 56/17381 1.98460797179952e-05 0.000184117213084704 0.000134064352251419 ZAP70/FOXP3/NCKAP1L/JAK3/IL12RB1/ZNF683/CD86/SASH3 8 BP GO:0071347 cellular response to interleukin-1 10/363 92/17381 2.19904336287796e-05 0.000203377364430142 0.000148088569059451 CCL4L1/CCL3L1/CCL3L3/CCL13/CCL3/CD40/XCL2/CCL5/CCL4/CCL18 10 BP GO:0050690 regulation of defense response to virus by virus 6/363 29/17381 2.51890082589546e-05 0.00023152119319496 0.000168581406801321 DOCK2/CD247/HCK/ELMO1/LCK/CD4 6 BP GO:0090023 positive regulation of neutrophil chemotaxis 6/363 29/17381 2.51890082589546e-05 0.00023152119319496 0.000168581406801321 RAC2/CD74/C3AR1/CCR7/NCKAP1L/C5AR1 6 BP GO:0035710 CD4-positive, alpha-beta T cell activation 9/363 75/17381 2.55261735365353e-05 0.000233898291667084 0.000170312283353078 BATF/FOXP3/GPR183/NCKAP1L/SLAMF6/JAK3/IL12RB1/CD86/SASH3 9 BP GO:0002313 mature B cell differentiation involved in immune response 5/363 18/17381 2.64708963752834e-05 0.000239605864454693 0.00017446823398843 DOCK10/PTK2B/GPR183/MFNG/PLCG2 5 BP GO:0031342 negative regulation of cell killing 5/363 18/17381 2.64708963752834e-05 0.000239605864454693 0.00017446823398843 LILRB1/PTPRC/HAVCR2/HLA-E/IL7R 5 BP GO:0045076 regulation of interleukin-2 biosynthetic process 5/363 18/17381 2.64708963752834e-05 0.000239605864454693 0.00017446823398843 LAG3/FOXP3/CD3E/CD4/CD86 5 BP GO:0072643 interferon-gamma secretion 5/363 18/17381 2.64708963752834e-05 0.000239605864454693 0.00017446823398843 BTN3A2/LILRB1/CD2/BTN3A1/RASGRP1 5 BP GO:0002437 inflammatory response to antigenic stimulus 7/363 43/17381 2.75832319739275e-05 0.000248165754738236 0.000180701090368232 SPN/BTK/RASGRP1/CCR7/FCER1G/IL2RA/CD6 7 BP GO:0019835 cytolysis 7/363 43/17381 2.75832319739275e-05 0.000248165754738236 0.000180701090368232 LYZ/LILRB1/GZMH/GZMA/GZMM/PRF1/GZMB 7 BP GO:0051056 regulation of small GTPase mediated signal transduction 19/363 309/17381 2.88276159718541e-05 0.000258580242060788 0.000188284365573936 RAC2/FGD2/PREX1/ARHGAP45/ARHGAP25/ARHGEF6/TAGAP/VAV1/GMIP/ARHGAP9/FGD3/CSF1/RASGRP1/ARHGDIB/RASAL3/APOE/ARHGAP30/RHOG/CYTH4 19 BP GO:0034121 regulation of toll-like receptor signaling pathway 8/363 59/17381 2.93389770083325e-05 0.000262376797389833 0.000191048815037664 TLR2/CD300LF/CD14/CD300A/TLR4/NR1H3/LY96/IRF1 8 BP GO:0001913 T cell mediated cytotoxicity 6/363 30/17381 3.09360540056998e-05 0.000274189192943375 0.000199649972593176 LILRB1/PTPRC/HLA-E/IL7R/IL12RB1/RAB27A 6 BP GO:0032733 positive regulation of interleukin-10 production 6/363 30/17381 3.09360540056998e-05 0.000274189192943375 0.000199649972593176 TLR2/TLR4/FCER1G/TIGIT/CD274/SASH3 6 BP GO:0070229 negative regulation of lymphocyte apoptotic process 6/363 30/17381 3.09360540056998e-05 0.000274189192943375 0.000199649972593176 CD74/DOCK8/IDO1/CD27/JAK3/CCL5 6 BP GO:0002886 regulation of myeloid leukocyte mediated immunity 7/363 44/17381 3.22190095364651e-05 0.00028387044496921 0.000206699344892925 RAC2/ITGAM/FGR/ITGB2/BTK/CD300A/FCER1G 7 BP GO:0031343 positive regulation of cell killing 7/363 44/17381 3.22190095364651e-05 0.00028387044496921 0.000206699344892925 LAG3/VAV1/PRF1/RASGRP1/HLA-E/SLAMF6/IL12RB1 7 BP GO:0042108 positive regulation of cytokine biosynthetic process 8/363 60/17381 3.32440255818759e-05 0.000292037487264975 0.000212646150283075 EBI3/CYBB/SPN/CD3E/TLR4/CD4/CD86/IRF1 8 BP GO:0070838 divalent metal ion transport 24/363 456/17381 3.4403187679732e-05 0.000301331449736005 0.000219413518948136 MCOLN2/CXCL9/LILRB1/LILRB2/PTPRC/CLIC2/PTPN6/CCR1/PTK2B/CXCL11/CXCL10/LCK/CD4/CCR7/IL16/CCL3/TRPV2/CORO1A/CCL5/CCR5/TRPM2/CCL4/SLC11A1/PLCG2 24 BP GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 9/363 78/17381 3.50825367836305e-05 0.000304428585037996 0.000221668687984968 PSMB10/PSME2/NCF4/CYBB/HLA-E/FCER1G/PSMB9/PSME1/IFI30 9 BP GO:0002710 negative regulation of T cell mediated immunity 5/363 19/17381 3.53116838901343e-05 0.000304428585037996 0.000221668687984968 LILRB1/PTPRC/FOXP3/SPN/IL7R 5 BP GO:0046641 positive regulation of alpha-beta T cell proliferation 5/363 19/17381 3.53116838901343e-05 0.000304428585037996 0.000221668687984968 ZAP70/EBI3/CD3E/HLA-E/RASAL3 5 BP GO:0070233 negative regulation of T cell apoptotic process 5/363 19/17381 3.53116838901343e-05 0.000304428585037996 0.000221668687984968 DOCK8/IDO1/CD27/JAK3/CCL5 5 BP GO:0090026 positive regulation of monocyte chemotaxis 5/363 19/17381 3.53116838901343e-05 0.000304428585037996 0.000221668687984968 AIF1/CCR1/CXCL10/PLA2G7/CCL5 5 BP GO:0002377 immunoglobulin production 12/363 139/17381 3.5462406402688e-05 0.000304428585037996 0.000221668687984968 POU2F2/PTPRC/HLA-DQB1/BATF/FOXP3/BTK/HLA-E/IL7R/TNFRSF4/CD40/TNFSF13B/SASH3 12 BP GO:0002524 hypersensitivity 4/363 10/17381 3.55745962368108e-05 0.000304428585037996 0.000221668687984968 SPN/BTK/CCR7/FCER1G 4 BP GO:0045059 positive thymic T cell selection 4/363 10/17381 3.55745962368108e-05 0.000304428585037996 0.000221668687984968 ZAP70/DOCK2/CD74/CD3D 4 BP GO:2000021 regulation of ion homeostasis 15/363 210/17381 3.68423160039834e-05 0.000314373687850609 0.000228910182380353 CXCL9/PTPRC/CLIC2/PTPN6/PTK2B/CXCL11/CXCL10/LCK/CD4/CCR7/CCL3/CORO1A/CCR5/TRPM2/PLCG2 15 BP GO:0048873 homeostasis of number of cells within a tissue 6/363 31/17381 3.76906130803483e-05 0.000320693273580792 0.000233511768257195 FLT3LG/CD7/CSF1/LIPA/CORO1A/SASH3 6 BP GO:0072511 divalent inorganic cation transport 24/363 460/17381 3.95335269122773e-05 0.000335415507534934 0.000244231715217548 MCOLN2/CXCL9/LILRB1/LILRB2/PTPRC/CLIC2/PTPN6/CCR1/PTK2B/CXCL11/CXCL10/LCK/CD4/CCR7/IL16/CCL3/TRPV2/CORO1A/CCL5/CCR5/TRPM2/CCL4/SLC11A1/PLCG2 24 BP GO:0002292 T cell differentiation involved in immune response 8/363 62/17381 4.236549623832e-05 0.000358421726698059 0.000260983619171469 BATF/FOXP3/GPR183/SLAMF6/FCER1G/JAK3/IL12RB1/CD86 8 BP GO:0034142 toll-like receptor 4 signaling pathway 6/363 32/17381 4.55784137742531e-05 0.000382345116111903 0.000278403357672235 ITGAM/CD14/ITGB2/TLR4/NR1H3/LY96 6 BP GO:0071624 positive regulation of granulocyte chemotaxis 6/363 32/17381 4.55784137742531e-05 0.000382345116111903 0.000278403357672235 RAC2/CD74/C3AR1/CCR7/NCKAP1L/C5AR1 6 BP GO:1902624 positive regulation of neutrophil migration 6/363 32/17381 4.55784137742531e-05 0.000382345116111903 0.000278403357672235 RAC2/CD74/C3AR1/CCR7/NCKAP1L/C5AR1 6 BP GO:0032703 negative regulation of interleukin-2 production 5/363 20/17381 4.62791080238669e-05 0.000387132538469313 0.000281889303752708 LAG3/HAVCR2/GBP1/FOXP3/VSIG4 5 BP GO:0045670 regulation of osteoclast differentiation 8/363 63/17381 4.7655851354227e-05 0.000397532563957669 0.000289462048620692 LILRB1/INPP5D/CCR1/CSF1/TYROBP/TLR4/CCL3/LILRB4 8 BP GO:0050798 activated T cell proliferation 7/363 47/17381 5.01110625915252e-05 0.000416845654741793 0.000303524813109503 PDCD1LG2/FOXP3/BTN3A1/IL12RB1/CD274/IL2RA/CD86 7 BP GO:0032633 interleukin-4 production 6/363 33/17381 5.47345489352222e-05 0.000451069785340019 0.00032844500293395 HAVCR2/FOXP3/CD3E/HLA-E/CD86/SASH3 6 BP GO:0032490 detection of molecule of bacterial origin 4/363 11/17381 5.49826501270741e-05 0.000451069785340019 0.00032844500293395 TLR2/TLR4/LY96/TREM2 4 BP GO:0035747 natural killer cell chemotaxis 4/363 11/17381 5.49826501270741e-05 0.000451069785340019 0.00032844500293395 PIK3CD/CCL3/CCL5/CCL4 4 BP GO:0070391 response to lipoteichoic acid 4/363 11/17381 5.49826501270741e-05 0.000451069785340019 0.00032844500293395 TLR2/CD14/TLR4/TREM2 4 BP GO:0071223 cellular response to lipoteichoic acid 4/363 11/17381 5.49826501270741e-05 0.000451069785340019 0.00032844500293395 TLR2/CD14/TLR4/TREM2 4 BP GO:0042094 interleukin-2 biosynthetic process 5/363 21/17381 5.97056900572935e-05 0.000484478324225123 0.000352771322294636 LAG3/FOXP3/CD3E/CD4/CD86 5 BP GO:0048305 immunoglobulin secretion 5/363 21/17381 5.97056900572935e-05 0.000484478324225123 0.000352771322294636 POU2F2/HLA-E/TNFRSF4/CD40/TNFSF13B 5 BP GO:0050855 regulation of B cell receptor signaling pathway 5/363 21/17381 5.97056900572935e-05 0.000484478324225123 0.000352771322294636 NFAM1/PTPN6/GCSAM/LPXN/CD300A 5 BP GO:1901623 regulation of lymphocyte chemotaxis 5/363 21/17381 5.97056900572935e-05 0.000484478324225123 0.000352771322294636 PTK2B/CXCL10/CCL3/CCL5/CCL4 5 BP GO:2000249 regulation of actin cytoskeleton reorganization 6/363 34/17381 6.53036397591149e-05 0.000528462606528924 0.000384798334965037 CSF1R/GMFG/HCK/PTK2B/ARHGDIB/TRPM2 6 BP GO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production 7/363 49/17381 6.60373739548719e-05 0.000532952031538235 0.000388067295241866 NLRC3/LILRB1/HAVCR2/FOXP3/TLR4/CD274/ACP5 7 BP GO:0002438 acute inflammatory response to antigenic stimulus 5/363 22/17381 7.59494339661396e-05 0.000608003802019257 0.000442715998783949 SPN/BTK/CCR7/FCER1G/CD6 5 BP GO:0002717 positive regulation of natural killer cell mediated immunity 5/363 22/17381 7.59494339661396e-05 0.000608003802019257 0.000442715998783949 LAG3/VAV1/RASGRP1/HLA-E/SLAMF6 5 BP GO:0050858 negative regulation of antigen receptor-mediated signaling pathway 5/363 22/17381 7.59494339661396e-05 0.000608003802019257 0.000442715998783949 GBP1/PTPN6/LPXN/CD300A/LILRB4 5 BP GO:0001912 positive regulation of leukocyte mediated cytotoxicity 6/363 35/17381 7.74399745826453e-05 0.000618274113423908 0.000450194292762098 LAG3/VAV1/RASGRP1/HLA-E/SLAMF6/IL12RB1 6 BP GO:0002430 complement receptor mediated signaling pathway 4/363 12/17381 8.11171813015128e-05 0.000638581906193963 0.000464981346279582 FPR3/C3AR1/FPR1/C5AR1 4 BP GO:0002716 negative regulation of natural killer cell mediated immunity 4/363 12/17381 8.11171813015128e-05 0.000638581906193963 0.000464981346279582 CD96/LILRB1/HAVCR2/HLA-E 4 BP GO:0032823 regulation of natural killer cell differentiation 4/363 12/17381 8.11171813015128e-05 0.000638581906193963 0.000464981346279582 FLT3LG/RASGRP1/ZNF683/IL15 4 BP GO:0045591 positive regulation of regulatory T cell differentiation 4/363 12/17381 8.11171813015128e-05 0.000638581906193963 0.000464981346279582 LILRB2/FOXP3/SOCS1/LILRB4 4 BP GO:0070486 leukocyte aggregation 4/363 12/17381 8.11171813015128e-05 0.000638581906193963 0.000464981346279582 RAC2/ZAP70/STK10/SEMA4D 4 BP GO:0051928 positive regulation of calcium ion transport 10/363 107/17381 8.12701620038657e-05 0.000638581906193963 0.000464981346279582 CXCL9/CCR1/CXCL11/CXCL10/CD4/CCL3/TRPV2/CCL5/CCL4/PLCG2 10 BP GO:0050856 regulation of T cell receptor signaling pathway 6/363 36/17381 9.13076227072727e-05 0.000715563422163837 0.000521035187747872 GBP1/PTPN6/CD300A/LCK/CCR7/LILRB4 6 BP GO:0001914 regulation of T cell mediated cytotoxicity 5/363 23/17381 9.53934546287304e-05 0.000741727696826003 0.000540086619582753 LILRB1/PTPRC/HLA-E/IL7R/IL12RB1 5 BP GO:0002888 positive regulation of myeloid leukocyte mediated immunity 5/363 23/17381 9.53934546287304e-05 0.000741727696826003 0.000540086619582753 ITGAM/FGR/ITGB2/BTK/FCER1G 5 BP GO:0032660 regulation of interleukin-17 production 5/363 23/17381 9.53934546287304e-05 0.000741727696826003 0.000540086619582753 FOXP3/TLR4/NCKAP1L/SLAMF6/IL15 5 BP GO:0042093 T-helper cell differentiation 7/363 53/17381 0.000110318568324918 0.000855543480394806 0.000622961213676894 BATF/FOXP3/GPR183/SLAMF6/JAK3/IL12RB1/CD86 7 BP GO:0042976 activation of Janus kinase activity 4/363 13/17381 0.00011524298975544 0.0008891026515329 0.000647397215424613 PTK2B/CD300A/SOCS1/CCL5 4 BP GO:0045579 positive regulation of B cell differentiation 4/363 13/17381 0.00011524298975544 0.0008891026515329 0.000647397215424613 INPP5D/BTK/CD27/NCKAP1L 4 BP GO:0071677 positive regulation of mononuclear cell migration 5/363 24/17381 0.000118445504279954 0.000909099772540473 0.000661958054304681 AIF1/CCR1/CXCL10/PLA2G7/CCL5 5 BP GO:0090025 regulation of monocyte chemotaxis 5/363 24/17381 0.000118445504279954 0.000909099772540473 0.000661958054304681 AIF1/CCR1/CXCL10/PLA2G7/CCL5 5 BP GO:0050730 regulation of peptidyl-tyrosine phosphorylation 15/363 233/17381 0.000119682426582202 0.000916232047202564 0.00066715139699455 CD74/PTPN6/SEMA4D/CSF1R/CD3E/ITGB2/PTK2B/SAMSN1/CD300A/CD4/SOCS1/CD40/CCL5/IL15/TREM2 15 BP GO:0032715 negative regulation of interleukin-6 production 6/363 38/17381 0.000124942550162055 0.000951608476681844 0.000692910629516312 NLRC3/HAVCR2/INPP5D/FOXP3/TLR4/NCKAP1L 6 BP GO:0033003 regulation of mast cell activation 6/363 38/17381 0.000124942550162055 0.000951608476681844 0.000692910629516312 RAC2/CD300LF/MILR1/FGR/CD300A/FCER1G 6 BP GO:0001894 tissue homeostasis 14/363 208/17381 0.000125840946507646 0.000956005966070839 0.000696112647169039 LYZ/RAC2/FLT3LG/CD7/CSF1R/INPP5D/CD38/PTK2B/CSF1/LIPA/TLR4/CORO1A/SASH3/ACP5 14 BP GO:0050714 positive regulation of protein secretion 15/363 235/17381 0.00013156255375499 0.000996929478581072 0.000725910970229758 CLEC5A/TLR2/HAVCR2/CD2/FGR/CSF1R/CD38/CD14/RASGRP1/HLA-E/TLR4/CASP1/CCL3/TNFRSF4/CD274 15 BP GO:0002294 CD4-positive, alpha-beta T cell differentiation involved in immune response 7/363 55/17381 0.000140134480628096 0.0010591890439352 0.000771245071049633 BATF/FOXP3/GPR183/SLAMF6/JAK3/IL12RB1/CD86 7 BP GO:0008154 actin polymerization or depolymerization 13/363 185/17381 0.000142279855105782 0.00107268204684815 0.00078106995740949 WAS/PREX1/WIPF1/GMFG/HCK/AIF1/PTK2B/EVL/CCR7/NCKAP1L/CORO1A/MICAL1/CORO7 13 BP GO:0038111 interleukin-7-mediated signaling pathway 6/363 39/17381 0.000145087550942543 0.00109108769370427 0.000794471969541834 PTK2B/IL7R/LCK/SOCS1/JAK3/IL2RG 6 BP GO:0001562 response to protozoan 5/363 25/17381 0.000145537406706952 0.00109171384678414 0.000794927900878485 IRF8/BATF/SPN/CD40/SLC11A1 5 BP GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 9/363 94/17381 0.000152731406021744 0.0011427993144039 0.000832125618632087 PSMB10/PSME2/NCF4/CYBB/HLA-E/FCER1G/PSMB9/PSME1/IFI30 9 BP GO:0002287 alpha-beta T cell activation involved in immune response 7/363 56/17381 0.000157318537900967 0.0011712365146727 0.000852832073884191 BATF/FOXP3/GPR183/SLAMF6/JAK3/IL12RB1/CD86 7 BP GO:0002293 alpha-beta T cell differentiation involved in immune response 7/363 56/17381 0.000157318537900967 0.0011712365146727 0.000852832073884191 BATF/FOXP3/GPR183/SLAMF6/JAK3/IL12RB1/CD86 7 BP GO:0002864 regulation of acute inflammatory response to antigenic stimulus 4/363 14/17381 0.000158689537359695 0.00117556577675913 0.000855984412047583 SPN/BTK/CCR7/FCER1G 4 BP GO:0070234 positive regulation of T cell apoptotic process 4/363 14/17381 0.000158689537359695 0.00117556577675913 0.000855984412047583 PDCD1/IDO1/CCL5/CD274 4 BP GO:0043029 T cell homeostasis 6/363 40/17381 0.000167719364038267 0.00123630758937119 0.000900213366125146 SIT1/FOXP3/NCKAP1L/JAK3/CORO1A/IL2RA 6 BP GO:0046638 positive regulation of alpha-beta T cell differentiation 6/363 40/17381 0.000167719364038267 0.00123630758937119 0.000900213366125146 ZAP70/FOXP3/NCKAP1L/IL12RB1/CD86/SASH3 6 BP GO:0032620 interleukin-17 production 5/363 26/17381 0.000177124408145599 0.00129920317107782 0.000946010580191688 FOXP3/TLR4/NCKAP1L/SLAMF6/IL15 5 BP GO:0045671 negative regulation of osteoclast differentiation 5/363 26/17381 0.000177124408145599 0.00129920317107782 0.000946010580191688 LILRB1/INPP5D/TLR4/CCL3/LILRB4 5 BP GO:1903532 positive regulation of secretion by cell 19/363 355/17381 0.000181589580632377 0.00132868248433223 0.000967475846638294 CLEC5A/TLR2/ITGAM/HAVCR2/CD2/FGR/CSF1R/CD38/CD14/ITGB2/RASGRP1/HLA-E/TLR4/CASP1/CCL3/FCER1G/TNFRSF4/CD274/RAB27A 19 BP GO:0046718 viral entry into host cell 10/363 118/17381 0.000184109074710935 0.00134053013322534 0.000976102673798807 CLEC5A/CD74/SELPLG/ITGB7/MRC1/CD4/TNFRSF4/CCR5/CD86/CXCR4 10 BP GO:0050728 negative regulation of inflammatory response 10/363 118/17381 0.000184109074710935 0.00134053013322534 0.000976102673798807 NLRC3/TNFRSF1B/FOXP3/SPN/TNFAIP8L2/APOE/ETS1/NR1H3/IL2RA/ACP5 10 BP GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation 6/363 41/17381 0.000193051810749549 0.00140221534734672 0.00102101856262919 FOXP3/NCKAP1L/JAK3/IL12RB1/CD86/SASH3 6 BP GO:0072677 eosinophil migration 4/363 15/17381 0.000212842106459631 0.00154080460532801 0.00112193188186197 CD300A/CCL13/CCL3/CCL5 4 BP GO:0032814 regulation of natural killer cell activation 5/363 27/17381 0.000213684453324537 0.00154080460532801 0.00112193188186197 FLT3LG/HAVCR2/RASGRP1/ZNF683/IL15 5 BP GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation 5/363 27/17381 0.000213684453324537 0.00154080460532801 0.00112193188186197 FOXP3/NCKAP1L/IL12RB1/CD86/SASH3 5 BP GO:0043901 negative regulation of multi-organism process 12/363 168/17381 0.000219010686206556 0.00157539570899305 0.00114711928193619 IRF8/APOBEC3C/HAVCR2/CARD16/APOBEC3D/ARHGDIB/APOBEC3G/CCL3/APOBEC3H/CCL5/IL2RA/CCL4 12 BP GO:0046006 regulation of activated T cell proliferation 6/363 43/17381 0.000252723599983108 0.00181352019457758 0.00132050885469931 PDCD1LG2/FOXP3/IL12RB1/CD274/IL2RA/CD86 6 BP GO:0001782 B cell homeostasis 5/363 28/17381 0.000255717394614235 0.00183059231048363 0.00133293986059039 DOCK10/CD74/FOXP3/NCKAP1L/TNFSF13B 5 BP GO:0061515 myeloid cell development 7/363 61/17381 0.000270677444130746 0.00193303939717353 0.00140753637488158 LILRB1/TLR2/EVI2B/PTPN6/TYROBP/FLI1/NCKAP1L 7 BP GO:0033209 tumor necrosis factor-mediated signaling pathway 12/363 172/17381 0.000272264910883851 0.00193972465218208 0.00141240422165886 TNFRSF1B/PSMB10/PSME2/CARD16/PTK2B/CD27/CASP1/TNFRSF4/CD40/TNFSF13B/PSMB9/PSME1 12 BP GO:0036037 CD8-positive, alpha-beta T cell activation 4/363 16/17381 0.000279133476283036 0.00197918926754972 0.00144114025349137 LILRB1/HLA-E/NCKAP1L/IRF1 4 BP GO:1900017 positive regulation of cytokine production involved in inflammatory response 4/363 16/17381 0.000279133476283036 0.00197918926754972 0.00144114025349137 GBP5/GPSM3/TLR4/CD6 4 BP GO:0043300 regulation of leukocyte degranulation 6/363 44/17381 0.000287540114264157 0.00203395358736023 0.00148101671554985 RAC2/ITGAM/FGR/ITGB2/CD300A/FCER1G 6 BP GO:0002831 regulation of response to biotic stimulus 10/363 125/17381 0.000294643207871259 0.00207925941478817 0.00151400600702119 LY86/LILRB1/HAVCR2/CARD16/SPN/APOBEC3G/IL12RB1/IL2RA/IL15/LY96 10 BP GO:2000108 positive regulation of leukocyte apoptotic process 5/363 29/17381 0.000303744141771584 0.00213841620377252 0.00155708083127899 PDCD1/IDO1/PIK3CD/CCL5/CD274 5 BP GO:0002793 positive regulation of peptide secretion 15/363 254/17381 0.000306102285048453 0.00214993538885446 0.00156546848857948 CLEC5A/TLR2/HAVCR2/CD2/FGR/CSF1R/CD38/CD14/RASGRP1/HLA-E/TLR4/CASP1/CCL3/TNFRSF4/CD274 15 BP GO:0014065 phosphatidylinositol 3-kinase signaling 10/363 126/17381 0.000314221679194599 0.00220176978974474 0.0016032115396678 NLRC3/HCST/PPP1R16B/FGR/PTPN6/SEMA4D/PIK3CD/RASGRP1/PIK3R5/CCL5 10 BP GO:0060627 regulation of vesicle-mediated transport 22/363 465/17381 0.00033016611288667 0.00230806263891198 0.00168060833344833 RAC2/LILRB1/DOCK2/TLR2/ITGAM/APOC1/CD300LF/FGR/HCK/CD14/TBC1D10C/ITGB2/CD300A/NCKAP1L/APOE/FCER1G/CORO1A/MICAL1/NR1H3/RAB27A/SLC11A1/PLCG2 22 BP GO:0019058 viral life cycle 17/363 313/17381 0.000332015027594213 0.00231555211282334 0.00168606176961439 CLEC5A/APOBEC3C/CD74/SELPLG/CXCR6/APOBEC3D/ITGB7/MRC1/APOBEC3G/CD4/APOE/TNFRSF4/APOBEC3H/CCL5/CCR5/CD86/CXCR4 17 BP GO:0032612 interleukin-1 production 8/363 83/17381 0.000338034425864361 0.00235202457996277 0.00171261907840773 GBP5/HAVCR2/CARD16/TLR4/CASP1/CCR7/CCL3/ACP5 8 BP GO:0009164 nucleoside catabolic process 5/363 30/17381 0.000358305759324761 0.00248653369675989 0.00181056145605506 TYMP/APOBEC3C/ADA2/APOBEC3G/APOBEC3H 5 BP GO:0043373 CD4-positive, alpha-beta T cell lineage commitment 4/363 17/17381 0.000359036094562375 0.00248653369675989 0.00181056145605506 BATF/FOXP3/SLAMF6/IL12RB1 4 BP GO:0002762 negative regulation of myeloid leukocyte differentiation 6/363 46/17381 0.000368400401343417 0.00253370991963209 0.00184491266990991 LILRB1/INPP5D/TLR4/CCL3/C1QC/LILRB4 6 BP GO:0050702 interleukin-1 beta secretion 6/363 46/17381 0.000368400401343417 0.00253370991963209 0.00184491266990991 GBP5/CARD16/TLR4/CASP1/CCR7/CCL3 6 BP GO:0050766 positive regulation of phagocytosis 6/363 46/17381 0.000368400401343417 0.00253370991963209 0.00184491266990991 DOCK2/CD300LF/NCKAP1L/FCER1G/RAB27A/SLC11A1 6 BP GO:0048015 phosphatidylinositol-mediated signaling 11/363 153/17381 0.000376207868822577 0.00258144477731252 0.00187967065189064 NLRC3/HCST/PPP1R16B/FGR/PTPN6/SEMA4D/CSF1R/PIK3CD/RASGRP1/PIK3R5/CCL5 11 BP GO:0006801 superoxide metabolic process 7/363 65/17381 0.00040222188028255 0.00275360174593433 0.00200502619088216 NRROS/PREX1/ITGAM/CYBB/NCF1C/ITGB2/ACP5 7 BP GO:0032720 negative regulation of tumor necrosis factor production 6/363 47/17381 0.000414979328965646 0.00283270792378469 0.00206262709801579 NLRC3/LILRB1/HAVCR2/FOXP3/TLR4/ACP5 6 BP GO:0042742 defense response to bacterium 16/363 290/17381 0.000415679436767599 0.00283270792378469 0.00206262709801579 LYZ/IRF8/TLR2/STAB1/HAVCR2/FGR/GNLY/SPN/RNASE6/HLA-E/TLR4/CD4/FCER1G/C5AR1/SLC11A1/ACP5 16 BP GO:0071353 cellular response to interleukin-4 5/363 31/17381 0.000419962518217917 0.00284885735592928 0.00207438625471504 CD300LF/MRC1/JAK3/CORO1A/IL2RG 5 BP GO:2000516 positive regulation of CD4-positive, alpha-beta T cell activation 5/363 31/17381 0.000419962518217917 0.00284885735592928 0.00207438625471504 FOXP3/NCKAP1L/IL12RB1/CD86/SASH3 5 BP GO:0045639 positive regulation of myeloid cell differentiation 8/363 86/17381 0.000430784822313955 0.00291563000193399 0.0021230065405903 CD74/EVI2B/INPP5D/CCR1/CSF1/CD4/NCKAP1L/ETS1 8 BP GO:0048017 inositol lipid-mediated signaling 11/363 156/17381 0.000443908198931248 0.00299763858598018 0.00218272082539294 NLRC3/HCST/PPP1R16B/FGR/PTPN6/SEMA4D/CSF1R/PIK3CD/RASGRP1/PIK3R5/CCL5 11 BP GO:0002363 alpha-beta T cell lineage commitment 4/363 18/17381 0.000454054722615829 0.00303178243038103 0.00220758255508286 BATF/FOXP3/SLAMF6/IL12RB1 4 BP GO:0030502 negative regulation of bone mineralization 4/363 18/17381 0.000454054722615829 0.00303178243038103 0.00220758255508286 SRGN/CCR1/PTK2B/CCL3 4 BP GO:0045655 regulation of monocyte differentiation 4/363 18/17381 0.000454054722615829 0.00303178243038103 0.00220758255508286 CD74/INPP5D/CSF1/CD4 4 BP GO:0097242 amyloid-beta clearance 4/363 18/17381 0.000454054722615829 0.00303178243038103 0.00220758255508286 ITGAM/MSR1/ITGB2/APOE 4 BP GO:0098581 detection of external biotic stimulus 4/363 18/17381 0.000454054722615829 0.00303178243038103 0.00220758255508286 TLR2/TLR4/LY96/TREM2 4 BP GO:0030041 actin filament polymerization 11/363 157/17381 0.000468626966507543 0.00312208301176614 0.00227333463088553 WAS/PREX1/GMFG/HCK/AIF1/PTK2B/EVL/CCR7/NCKAP1L/CORO1A/CORO7 11 BP GO:0045638 negative regulation of myeloid cell differentiation 8/363 88/17381 0.000503372551614778 0.00334607914890359 0.00243643669249634 GPR171/LILRB1/INPP5D/PTK2B/TLR4/CCL3/C1QC/LILRB4 8 BP GO:0030260 entry into host cell 10/363 134/17381 0.00051355065347988 0.00338352620810416 0.00246370364734176 CLEC5A/CD74/SELPLG/ITGB7/MRC1/CD4/TNFRSF4/CCR5/CD86/CXCR4 10 BP GO:0044409 entry into host 10/363 134/17381 0.00051355065347988 0.00338352620810416 0.00246370364734176 CLEC5A/CD74/SELPLG/ITGB7/MRC1/CD4/TNFRSF4/CCR5/CD86/CXCR4 10 BP GO:0051806 entry into cell of other organism involved in symbiotic interaction 10/363 134/17381 0.00051355065347988 0.00338352620810416 0.00246370364734176 CLEC5A/CD74/SELPLG/ITGB7/MRC1/CD4/TNFRSF4/CCR5/CD86/CXCR4 10 BP GO:0051828 entry into other organism involved in symbiotic interaction 10/363 134/17381 0.00051355065347988 0.00338352620810416 0.00246370364734176 CLEC5A/CD74/SELPLG/ITGB7/MRC1/CD4/TNFRSF4/CCR5/CD86/CXCR4 10 BP GO:0051047 positive regulation of secretion 19/363 386/17381 0.000516198684944741 0.00339346508557492 0.00247094060877464 CLEC5A/TLR2/ITGAM/HAVCR2/CD2/FGR/CSF1R/CD38/CD14/ITGB2/RASGRP1/HLA-E/TLR4/CASP1/CCL3/FCER1G/TNFRSF4/CD274/RAB27A 19 BP GO:0002381 immunoglobulin production involved in immunoglobulin mediated immune response 6/363 49/17381 0.000521842757737941 0.00340799941347278 0.00248152373254884 POU2F2/HLA-DQB1/BATF/FOXP3/BTK/CD40 6 BP GO:0045806 negative regulation of endocytosis 6/363 49/17381 0.000521842757737941 0.00340799941347278 0.00248152373254884 LILRB1/TLR2/APOC1/CD300LF/CD300A/NR1H3 6 BP GO:2000514 regulation of CD4-positive, alpha-beta T cell activation 6/363 49/17381 0.000521842757737941 0.00340799941347278 0.00248152373254884 FOXP3/NCKAP1L/JAK3/IL12RB1/CD86/SASH3 6 BP GO:0010959 regulation of metal ion transport 18/363 356/17381 0.000526573569151401 0.00343136999766493 0.00249854094771827 CXCL9/LILRB1/KCNAB2/LILRB2/CLIC2/PTPN6/CCR1/PTK2B/CXCL11/CXCL10/CD4/IL16/CCL3/TRPV2/CORO1A/CCL5/CCL4/PLCG2 18 BP GO:0032675 regulation of interleukin-6 production 9/363 111/17381 0.000532275773670743 0.00346095470303815 0.00252008295509476 NLRC3/TLR2/LILRB2/HAVCR2/INPP5D/FOXP3/TLR4/NCKAP1L/FCER1G 9 BP GO:0010528 regulation of transposition 4/363 19/17381 0.00056571953294268 0.00362276010118321 0.00263790103157803 APOBEC3C/APOBEC3D/APOBEC3G/APOBEC3H 4 BP GO:0010529 negative regulation of transposition 4/363 19/17381 0.00056571953294268 0.00362276010118321 0.00263790103157803 APOBEC3C/APOBEC3D/APOBEC3G/APOBEC3H 4 BP GO:0042454 ribonucleoside catabolic process 4/363 19/17381 0.00056571953294268 0.00362276010118321 0.00263790103157803 APOBEC3C/ADA2/APOBEC3G/APOBEC3H 4 BP GO:0042533 tumor necrosis factor biosynthetic process 4/363 19/17381 0.00056571953294268 0.00362276010118321 0.00263790103157803 LILRB1/CYBB/SPN/TLR4 4 BP GO:0042534 regulation of tumor necrosis factor biosynthetic process 4/363 19/17381 0.00056571953294268 0.00362276010118321 0.00263790103157803 LILRB1/CYBB/SPN/TLR4 4 BP GO:0070230 positive regulation of lymphocyte apoptotic process 4/363 19/17381 0.00056571953294268 0.00362276010118321 0.00263790103157803 PDCD1/IDO1/CCL5/CD274 4 BP GO:0030224 monocyte differentiation 5/363 33/17381 0.000566892614893008 0.00362276010118321 0.00263790103157803 CD74/CSF1R/INPP5D/CSF1/CD4 5 BP GO:1903131 mononuclear cell differentiation 5/363 33/17381 0.000566892614893008 0.00362276010118321 0.00263790103157803 CD74/CSF1R/INPP5D/CSF1/CD4 5 BP GO:0007249 I-kappaB kinase/NF-kappaB signaling 15/363 270/17381 0.000581607279229964 0.00370883614035724 0.0027005770206553 NLRC3/TLR2/CD74/CARD16/CD14/BTK/S100B/CD27/TLR4/CASP1/CD4/CCR7/CD40/APOL3/LY96 15 BP GO:0030838 positive regulation of actin filament polymerization 8/363 91/17381 0.000630547460304472 0.00400377470530217 0.00291533558125286 WAS/GMFG/HCK/PTK2B/EVL/CCR7/NCKAP1L/CORO1A 8 BP GO:0050830 defense response to Gram-positive bacterium 8/363 91/17381 0.000630547460304472 0.00400377470530217 0.00291533558125286 LYZ/TLR2/HAVCR2/FGR/RNASE6/HLA-E/C5AR1/ACP5 8 BP GO:0032611 interleukin-1 beta production 7/363 70/17381 0.00063362280083409 0.0040147419167743 0.0029233213207575 GBP5/CARD16/TLR4/CASP1/CCR7/CCL3/ACP5 7 BP GO:0070670 response to interleukin-4 5/363 34/17381 0.000653373472674714 0.00412234364751123 0.00300167117241283 CD300LF/MRC1/JAK3/CORO1A/IL2RG 5 BP GO:1900015 regulation of cytokine production involved in inflammatory response 5/363 34/17381 0.000653373472674714 0.00412234364751123 0.00300167117241283 GBP5/NLRC3/GPSM3/TLR4/CD6 5 BP GO:0009988 cell-cell recognition 7/363 71/17381 0.000690537946503864 0.00434761523189959 0.00316570194680752 DOCK2/DOCK8/HAVCR2/PRF1/CCR7/HVCN1/CD6 7 BP GO:0045954 positive regulation of natural killer cell mediated cytotoxicity 4/363 20/17381 0.000695579639172384 0.00436091824306392 0.00317538849129111 LAG3/VAV1/RASGRP1/SLAMF6 4 BP GO:0070168 negative regulation of biomineral tissue development 4/363 20/17381 0.000695579639172384 0.00436091824306392 0.00317538849129111 SRGN/CCR1/PTK2B/CCL3 4 BP GO:0001959 regulation of cytokine-mediated signaling pathway 11/363 165/17381 0.000711066907417586 0.00444864968548229 0.00323926985687799 CD74/PTPRC/CD300LF/CARD16/PTPN6/CSF1/CASP1/SOCS1/CCL5/NR1H3/TREM2 11 BP GO:0070588 calcium ion transmembrane transport 16/363 305/17381 0.000717803908560378 0.00448138373101217 0.00326310504608712 MCOLN2/CXCL9/PTPRC/CLIC2/PTPN6/PTK2B/CXCL11/CXCL10/LCK/CCR7/CCL3/TRPV2/CORO1A/CCR5/TRPM2/PLCG2 16 BP GO:0050701 interleukin-1 secretion 6/363 52/17381 0.000720896636883219 0.00449127653690005 0.00327030846064618 GBP5/CARD16/TLR4/CASP1/CCR7/CCL3 6 BP GO:0034122 negative regulation of toll-like receptor signaling pathway 5/363 35/17381 0.000749362389023392 0.00465887514511829 0.00339234484427687 CD300LF/CD14/CD300A/TLR4/LY96 5 BP GO:0032722 positive regulation of chemokine production 6/363 53/17381 0.000798842773294917 0.00494630091365195 0.00360163298650561 MCOLN2/TLR2/CD74/HAVCR2/CSF1R/TLR4 6 BP GO:0022604 regulation of cell morphogenesis 20/363 432/17381 0.000798915627759096 0.00494630091365195 0.00360163298650561 PLXNC1/FGD2/PREX1/GBP1/FGR/LST1/SEMA4D/CSF1R/HCK/FMNL1/ITGB2/FGD3/PTK2B/S100B/CCL13/CCL3/TRPV2/APOE/CORO1A/PLEKHO1 20 BP GO:0032652 regulation of interleukin-1 production 7/363 73/17381 0.000816487780900089 0.00504460707784329 0.00367321430149418 HAVCR2/CARD16/TLR4/CASP1/CCR7/CCL3/ACP5 7 BP GO:0009595 detection of biotic stimulus 4/363 21/17381 0.00084519703896417 0.00514938725040082 0.00374950964470174 TLR2/TLR4/LY96/TREM2 4 BP GO:0043369 CD4-positive or CD8-positive, alpha-beta T cell lineage commitment 4/363 21/17381 0.00084519703896417 0.00514938725040082 0.00374950964470174 BATF/FOXP3/SLAMF6/IL12RB1 4 BP GO:0046135 pyrimidine nucleoside catabolic process 4/363 21/17381 0.00084519703896417 0.00514938725040082 0.00374950964470174 TYMP/APOBEC3C/APOBEC3G/APOBEC3H 4 BP GO:0050857 positive regulation of antigen receptor-mediated signaling pathway 4/363 21/17381 0.00084519703896417 0.00514938725040082 0.00374950964470174 NFAM1/PTPRC/LCK/CCR7 4 BP GO:0072539 T-helper 17 cell differentiation 4/363 21/17381 0.00084519703896417 0.00514938725040082 0.00374950964470174 BATF/FOXP3/SLAMF6/IL12RB1 4 BP GO:1901739 regulation of myoblast fusion 4/363 21/17381 0.00084519703896417 0.00514938725040082 0.00374950964470174 CXCL9/FLT3LG/CXCL10/CD53 4 BP GO:0072593 reactive oxygen species metabolic process 14/363 251/17381 0.000845550827886501 0.00514938725040082 0.00374950964470174 RAC2/NRROS/TLR2/PREX1/ITGAM/VAV1/CYBB/AIF1/NCF1C/ITGB2/PTK2B/TLR4/RAB27A/ACP5 14 BP GO:0045807 positive regulation of endocytosis 9/363 119/17381 0.000880988974729047 0.00535425544233286 0.00389868375497709 DOCK2/CD300LF/CD14/NCKAP1L/APOE/FCER1G/RAB27A/SLC11A1/PLCG2 9 BP GO:0032635 interleukin-6 production 9/363 120/17381 0.000935283284666805 0.00567265503408909 0.00413052538624422 NLRC3/TLR2/LILRB2/HAVCR2/INPP5D/FOXP3/TLR4/NCKAP1L/FCER1G 9 BP GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent 7/363 75/17381 0.000959915181184345 0.00577807554239322 0.00420728698785127 PSMB10/PSME2/NCF4/CYBB/HLA-E/PSMB9/PSME1 7 BP GO:0002702 positive regulation of production of molecular mediator of immune response 7/363 75/17381 0.000959915181184345 0.00577807554239322 0.00420728698785127 CD74/HLA-E/TLR4/FCER1G/TNFRSF4/CD40/SASH3 7 BP GO:0010522 regulation of calcium ion transport into cytosol 8/363 97/17381 0.00096252342152377 0.00577807554239322 0.00420728698785127 CXCL9/CLIC2/PTPN6/PTK2B/CXCL11/CXCL10/CD4/CORO1A 8 BP GO:0014066 regulation of phosphatidylinositol 3-kinase signaling 8/363 97/17381 0.00096252342152377 0.00577807554239322 0.00420728698785127 NLRC3/HCST/PPP1R16B/FGR/PTPN6/SEMA4D/RASGRP1/CCL5 8 BP GO:0001768 establishment of T cell polarity 3/363 10/17381 0.000972067107702822 0.00577807554239322 0.00420728698785127 DOCK2/DOCK8/CCR7 3 BP GO:0002468 dendritic cell antigen processing and presentation 3/363 10/17381 0.000972067107702822 0.00577807554239322 0.00420728698785127 CD74/CCR7/SLC11A1 3 BP GO:0033089 positive regulation of T cell differentiation in thymus 3/363 10/17381 0.000972067107702822 0.00577807554239322 0.00420728698785127 FOXP3/RASGRP1/IL7R 3 BP GO:0045006 DNA deamination 3/363 10/17381 0.000972067107702822 0.00577807554239322 0.00420728698785127 APOBEC3D/APOBEC3G/APOBEC3H 3 BP GO:0051132 NK T cell activation 3/363 10/17381 0.000972067107702822 0.00577807554239322 0.00420728698785127 RASAL3/CD300A/IL15 3 BP GO:1900225 regulation of NLRP3 inflammasome complex assembly 3/363 10/17381 0.000972067107702822 0.00577807554239322 0.00420728698785127 GBP5/NLRC3/TLR4 3 BP GO:0002825 regulation of T-helper 1 type immune response 4/363 22/17381 0.00101614095118596 0.00599221337154807 0.004363210754441 HAVCR2/JAK3/IL12RB1/SLC11A1 4 BP GO:0043302 positive regulation of leukocyte degranulation 4/363 22/17381 0.00101614095118596 0.00599221337154807 0.004363210754441 ITGAM/FGR/ITGB2/FCER1G 4 BP GO:0071402 cellular response to lipoprotein particle stimulus 4/363 22/17381 0.00101614095118596 0.00599221337154807 0.004363210754441 ITGB2/TLR4/APOE/FCER1G 4 BP GO:0071800 podosome assembly 4/363 22/17381 0.00101614095118596 0.00599221337154807 0.004363210754441 BIN2/HCK/NCF1C/LCP1 4 BP GO:0060759 regulation of response to cytokine stimulus 11/363 173/17381 0.00104978546063431 0.00617838162404933 0.00449876856439915 CD74/PTPRC/CD300LF/CARD16/PTPN6/CSF1/CASP1/SOCS1/CCL5/NR1H3/TREM2 11 BP GO:0045453 bone resorption 6/363 56/17381 0.00107213035864875 0.00629744419734909 0.00458546359143866 RAC2/CSF1R/INPP5D/CD38/PTK2B/ACP5 6 BP GO:0030225 macrophage differentiation 5/363 38/17381 0.00110084966897765 0.00642809865532439 0.00468059921175223 SPI1/TLR2/CSF1R/CSF1/C1QC 5 BP GO:0045581 negative regulation of T cell differentiation 5/363 38/17381 0.00110084966897765 0.00642809865532439 0.00468059921175223 CD74/CTLA4/FOXP3/JAK3/IRF1 5 BP GO:1901658 glycosyl compound catabolic process 5/363 38/17381 0.00110084966897765 0.00642809865532439 0.00468059921175223 TYMP/APOBEC3C/ADA2/APOBEC3G/APOBEC3H 5 BP GO:0051279 regulation of release of sequestered calcium ion into cytosol 7/363 77/17381 0.00112246770141183 0.00654150452994998 0.00476317533197729 CXCL9/CLIC2/PTPN6/PTK2B/CXCL11/CXCL10/CORO1A 7 BP GO:0002861 regulation of inflammatory response to antigenic stimulus 4/363 23/17381 0.00120998252940853 0.00701036570540584 0.00510457507798807 SPN/BTK/CCR7/FCER1G 4 BP GO:0042832 defense response to protozoan 4/363 23/17381 0.00120998252940853 0.00701036570540584 0.00510457507798807 IRF8/BATF/CD40/SLC11A1 4 BP GO:0072538 T-helper 17 type immune response 4/363 23/17381 0.00120998252940853 0.00701036570540584 0.00510457507798807 BATF/FOXP3/SLAMF6/IL12RB1 4 BP GO:0002673 regulation of acute inflammatory response 10/363 150/17381 0.00122897877400191 0.00710659959024795 0.00517464746948173 SERPING1/C3AR1/SPN/BTK/C1QA/CCR7/FCER1G/C1QC/C5AR1/C1QB 10 BP GO:0033628 regulation of cell adhesion mediated by integrin 5/363 39/17381 0.00124140292162987 0.00715067292188346 0.00520673932313454 FERMT3/PTPN6/LPXN/NCKAP1L/CCL5 5 BP GO:0043030 regulation of macrophage activation 5/363 39/17381 0.00124140292162987 0.00715067292188346 0.00520673932313454 CD74/ITGAM/HAVCR2/TLR4/NR1H3 5 BP GO:0046427 positive regulation of JAK-STAT cascade 7/363 79/17381 0.00130586562462654 0.00736648480213668 0.00536388204460838 CSF1R/PTK2B/CD300A/SOCS1/CD40/CCL5/IL15 7 BP GO:1904894 positive regulation of STAT cascade 7/363 79/17381 0.00130586562462654 0.00736648480213668 0.00536388204460838 CSF1R/PTK2B/CD300A/SOCS1/CD40/CCL5/IL15 7 BP GO:0001767 establishment of lymphocyte polarity 3/363 11/17381 0.00131597377929373 0.00736648480213668 0.00536388204460838 DOCK2/DOCK8/CCR7 3 BP GO:0002676 regulation of chronic inflammatory response 3/363 11/17381 0.00131597377929373 0.00736648480213668 0.00536388204460838 IDO1/FOXP3/CCL5 3 BP GO:0002863 positive regulation of inflammatory response to antigenic stimulus 3/363 11/17381 0.00131597377929373 0.00736648480213668 0.00536388204460838 BTK/CCR7/FCER1G 3 BP GO:0033004 negative regulation of mast cell activation 3/363 11/17381 0.00131597377929373 0.00736648480213668 0.00536388204460838 CD300LF/MILR1/CD300A 3 BP GO:0039692 single stranded viral RNA replication via double stranded DNA intermediate 3/363 11/17381 0.00131597377929373 0.00736648480213668 0.00536388204460838 APOBEC3D/APOBEC3G/APOBEC3H 3 BP GO:0042535 positive regulation of tumor necrosis factor biosynthetic process 3/363 11/17381 0.00131597377929373 0.00736648480213668 0.00536388204460838 CYBB/SPN/TLR4 3 BP GO:0044546 NLRP3 inflammasome complex assembly 3/363 11/17381 0.00131597377929373 0.00736648480213668 0.00536388204460838 GBP5/NLRC3/TLR4 3 BP GO:0045953 negative regulation of natural killer cell mediated cytotoxicity 3/363 11/17381 0.00131597377929373 0.00736648480213668 0.00536388204460838 LILRB1/HAVCR2/HLA-E 3 BP GO:0046007 negative regulation of activated T cell proliferation 3/363 11/17381 0.00131597377929373 0.00736648480213668 0.00536388204460838 PDCD1LG2/FOXP3/CD274 3 BP GO:0046133 pyrimidine ribonucleoside catabolic process 3/363 11/17381 0.00131597377929373 0.00736648480213668 0.00536388204460838 APOBEC3C/APOBEC3G/APOBEC3H 3 BP GO:0048245 eosinophil chemotaxis 3/363 11/17381 0.00131597377929373 0.00736648480213668 0.00536388204460838 CCL13/CCL3/CCL5 3 BP GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response 3/363 11/17381 0.00131597377929373 0.00736648480213668 0.00536388204460838 CD74/TLR4/FCER1G 3 BP GO:1902563 regulation of neutrophil activation 3/363 11/17381 0.00131597377929373 0.00736648480213668 0.00536388204460838 ITGAM/ITGB2/CD300A 3 BP GO:0046777 protein autophosphorylation 13/363 234/17381 0.00132894511259314 0.00742513798368172 0.00540659016874071 SLA/ZAP70/STK10/MAP4K1/FGR/CSF1R/HCK/BTK/PTK2B/LCK/JAK3/STK17B/SLA2 13 BP GO:0007520 myoblast fusion 5/363 40/17381 0.0013947862870001 0.00776387581810521 0.00565324102551933 CXCL9/FLT3LG/CXCL10/PLEKHO1/CD53 5 BP GO:0050706 regulation of interleukin-1 beta secretion 5/363 40/17381 0.0013947862870001 0.00776387581810521 0.00565324102551933 CARD16/TLR4/CASP1/CCR7/CCL3 5 BP GO:0032196 transposition 4/363 24/17381 0.00142828993443424 0.00792075870529827 0.00576747479159961 APOBEC3C/APOBEC3D/APOBEC3G/APOBEC3H 4 BP GO:2000406 positive regulation of T cell migration 4/363 24/17381 0.00142828993443424 0.00792075870529827 0.00576747479159961 DOCK8/AIF1/CXCL10/CCL5 4 BP GO:0001961 positive regulation of cytokine-mediated signaling pathway 5/363 41/17381 0.00156169385314601 0.00864446894919854 0.00629444206120286 CD74/CD300LF/CSF1/CASP1/TREM2 5 BP GO:0002360 T cell lineage commitment 4/363 25/17381 0.00167262374923944 0.00922421023191677 0.0067165787981155 BATF/FOXP3/SLAMF6/IL12RB1 4 BP GO:0002719 negative regulation of cytokine production involved in immune response 4/363 25/17381 0.00167262374923944 0.00922421023191677 0.0067165787981155 CD96/LILRB1/FOXP3/JAK3 4 BP GO:0032651 regulation of interleukin-1 beta production 6/363 61/17381 0.00168043250206188 0.00925014416107258 0.00673546250461614 CARD16/TLR4/CASP1/CCR7/CCL3/ACP5 6 BP GO:0002526 acute inflammatory response 12/363 212/17381 0.00172094493401588 0.00943994660124217 0.00687366653655186 SERPING1/CD163/C3AR1/SPN/BTK/C1QA/CCR7/FCER1G/C1QC/C5AR1/C1QB/CD6 12 BP GO:0032700 negative regulation of interleukin-17 production 3/363 12/17381 0.00172759264529113 0.00943994660124217 0.00687366653655186 FOXP3/TLR4/NCKAP1L 3 BP GO:0043922 negative regulation by host of viral transcription 3/363 12/17381 0.00172759264529113 0.00943994660124217 0.00687366653655186 CCL3/CCL5/CCL4 3 BP GO:0045086 positive regulation of interleukin-2 biosynthetic process 3/363 12/17381 0.00172759264529113 0.00943994660124217 0.00687366653655186 CD3E/CD4/CD86 3 BP GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling 11/363 185/17381 0.00179883063450238 0.00981120444972177 0.00714399673621535 TLR2/CD74/CARD16/S100B/CD27/TLR4/CASP1/CD4/CCR7/CD40/APOL3 11 BP GO:0002262 myeloid cell homeostasis 9/363 133/17381 0.00192291878258861 0.0104688338840016 0.00762284747836532 SPI1/INPP5D/PIK3CD/FOXP3/NCKAP1L/FCER1G/ETS1/JAK3/IKZF1 9 BP GO:0033032 regulation of myeloid cell apoptotic process 4/363 26/17381 0.00194453272034741 0.0105671869364865 0.00769446293491294 CLEC5A/PIK3CD/FCER1G/CCL5 4 BP GO:0007265 Ras protein signal transduction 16/363 338/17381 0.00208197185480811 0.0112934648153343 0.00822329981958527 WAS/FGD2/PREX1/ARHGEF6/VAV1/AIF1/FGD3/CSF1/RASGRP1/ARHGDIB/RASAL3/ELMO1/APOE/DOK2/RHOG/CYTH4 16 BP GO:0045342 MHC class II biosynthetic process 3/363 13/17381 0.00221129754195184 0.0119082171427352 0.0086709297352637 SPI1/TLR4/SLC11A1 3 BP GO:0046629 gamma-delta T cell activation 3/363 13/17381 0.00221129754195184 0.0119082171427352 0.0086709297352637 LILRB1/JAML/NCKAP1L 3 BP GO:0072540 T-helper 17 cell lineage commitment 3/363 13/17381 0.00221129754195184 0.0119082171427352 0.0086709297352637 BATF/SLAMF6/IL12RB1 3 BP GO:1905809 negative regulation of synapse organization 3/363 13/17381 0.00221129754195184 0.0119082171427352 0.0086709297352637 TLR2/LILRB2/APOE 3 BP GO:0060142 regulation of syncytium formation by plasma membrane fusion 4/363 27/17381 0.00224554981026444 0.0120708435649233 0.00878934563774415 CXCL9/FLT3LG/CXCL10/CD53 4 BP GO:0050704 regulation of interleukin-1 secretion 5/363 45/17381 0.0023786793741139 0.0127404805325741 0.00927693962641923 CARD16/TLR4/CASP1/CCR7/CCL3 5 BP GO:0060760 positive regulation of response to cytokine stimulus 5/363 45/17381 0.0023786793741139 0.0127404805325741 0.00927693962641923 CD74/CD300LF/CSF1/CASP1/TREM2 5 BP GO:0048871 multicellular organismal homeostasis 16/363 343/17381 0.0024109824928524 0.0128903157337782 0.00938604164277794 LYZ/RAC2/FLT3LG/CD7/CSF1R/INPP5D/CD38/PTK2B/CSF1/LIPA/TLR4/CORO1A/TRPM2/SLC11A1/SASH3/ACP5 16 BP GO:1903305 regulation of regulated secretory pathway 8/363 112/17381 0.00241960347322016 0.0129132242710567 0.00940272241998404 RAC2/ITGAM/FGR/ITGB2/CD300A/FCER1G/MICAL1/RAB27A 8 BP GO:0032102 negative regulation of response to external stimulus 14/363 282/17381 0.00252551707137207 0.0134543646485618 0.00979675203281513 NLRC3/SERPING1/TNFRSF1B/HAVCR2/CARD16/FOXP3/SPN/AIF1/TNFAIP8L2/APOE/ETS1/NR1H3/IL2RA/ACP5 14 BP GO:0042036 negative regulation of cytokine biosynthetic process 4/363 28/17381 0.00257718854620613 0.0136806907140853 0.00996155062423236 LILRB1/LAG3/INPP5D/FOXP3 4 BP GO:0055094 response to lipoprotein particle 4/363 28/17381 0.00257718854620613 0.0136806907140853 0.00996155062423236 ITGB2/TLR4/APOE/FCER1G 4 BP GO:0045620 negative regulation of lymphocyte differentiation 5/363 46/17381 0.00262383534640298 0.013903526088235 0.010123807480034 CD74/CTLA4/FOXP3/JAK3/IRF1 5 BP GO:0031589 cell-substrate adhesion 15/363 316/17381 0.00276386348264787 0.0146059026214456 0.0106352406773101 RAC2/CD96/FERMT3/PREX1/GBP1/SIGLEC1/ITGB7/ITGB2/PARVG/PTK2B/CSF1/MYO1G/ITGAL/CCR7/CORO1A 15 BP GO:0031532 actin cytoskeleton reorganization 7/363 90/17381 0.00277035554320404 0.0146059026214456 0.0106352406773101 CSF1R/GMFG/HCK/PARVG/PTK2B/ARHGDIB/TRPM2 7 BP GO:0033033 negative regulation of myeloid cell apoptotic process 3/363 14/17381 0.00277109972502242 0.0146059026214456 0.0106352406773101 CLEC5A/FCER1G/CCL5 3 BP GO:0032273 positive regulation of protein polymerization 8/363 115/17381 0.00285251540723784 0.0150084644571631 0.0109283647738701 WAS/GMFG/HCK/PTK2B/EVL/CCR7/NCKAP1L/CORO1A 8 BP GO:0031529 ruffle organization 5/363 47/17381 0.00288679439609791 0.0151087411451311 0.011001380919363 CSF1R/AIF1/EVL/CCR7/RHOG 5 BP GO:0032648 regulation of interferon-beta production 5/363 47/17381 0.00288679439609791 0.0151087411451311 0.011001380919363 NLRC3/LILRB1/TLR2/TLR4/IRF1 5 BP GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation 5/363 47/17381 0.00288679439609791 0.0151087411451311 0.011001380919363 PTPN6/SEMA4D/SAMSN1/CD300A/SOCS1 5 BP GO:0035666 TRIF-dependent toll-like receptor signaling pathway 4/363 29/17381 0.00294093965091566 0.0153382106487335 0.0111684683950341 CD300LF/CD14/TLR4/LY96 4 BP GO:0042554 superoxide anion generation 4/363 29/17381 0.00294093965091566 0.0153382106487335 0.0111684683950341 ITGAM/CYBB/ITGB2/ACP5 4 BP GO:0048525 negative regulation of viral process 7/363 91/17381 0.00294867288344567 0.0153516570750021 0.0111782593667613 APOBEC3C/APOBEC3D/APOBEC3G/CCL3/APOBEC3H/CCL5/CCL4 7 BP GO:0030833 regulation of actin filament polymerization 9/363 142/17381 0.00299904284656243 0.0155866485114536 0.0113493676199478 WAS/PREX1/GMFG/HCK/PTK2B/EVL/CCR7/NCKAP1L/CORO1A 9 BP GO:0007015 actin filament organization 16/363 352/17381 0.00311224219065101 0.016146789623273 0.0117572325559161 WAS/RAC2/PREX1/WIPF1/ARHGAP25/GMFG/HCK/AIF1/LCP1/PTK2B/EVL/CCR7/NCKAP1L/CORO1A/MICAL1/CORO7 16 BP GO:0048010 vascular endothelial growth factor receptor signaling pathway 7/363 92/17381 0.00313564661964702 0.0162399228405371 0.0118250472063576 NCF4/VAV1/CYBB/PTK2B/ELMO1/NCKAP1L/SH2D2A 7 BP GO:0050688 regulation of defense response to virus 6/363 69/17381 0.00315689281076313 0.0162955678851146 0.011865564965302 LILRB1/SPN/APOBEC3G/IL12RB1/IL2RA/IL15 6 BP GO:0002712 regulation of B cell mediated immunity 5/363 48/17381 0.00316827864522543 0.0162955678851146 0.011865564965302 PTPN6/FOXP3/BTK/FCER1G/CD40 5 BP GO:0002889 regulation of immunoglobulin mediated immune response 5/363 48/17381 0.00316827864522543 0.0162955678851146 0.011865564965302 PTPN6/FOXP3/BTK/FCER1G/CD40 5 BP GO:1903307 positive regulation of regulated secretory pathway 5/363 48/17381 0.00316827864522543 0.0162955678851146 0.011865564965302 ITGAM/FGR/ITGB2/FCER1G/RAB27A 5 BP GO:0030851 granulocyte differentiation 4/363 30/17381 0.00333826794192965 0.0170228800189495 0.0123951549393927 SPI1/EVI2B/INPP5D/C1QC 4 BP GO:0032743 positive regulation of interleukin-2 production 4/363 30/17381 0.00333826794192965 0.0170228800189495 0.0123951549393927 CD3E/CD4/CD86/SASH3 4 BP GO:0033006 regulation of mast cell activation involved in immune response 4/363 30/17381 0.00333826794192965 0.0170228800189495 0.0123951549393927 RAC2/FGR/CD300A/FCER1G 4 BP GO:0043304 regulation of mast cell degranulation 4/363 30/17381 0.00333826794192965 0.0170228800189495 0.0123951549393927 RAC2/FGR/CD300A/FCER1G 4 BP GO:0046636 negative regulation of alpha-beta T cell activation 4/363 30/17381 0.00333826794192965 0.0170228800189495 0.0123951549393927 LILRB1/FOXP3/CD300A/JAK3 4 BP GO:0002830 positive regulation of type 2 immune response 3/363 15/17381 0.00341066412966312 0.0172737377179197 0.0125778161602328 CD74/IDO1/CD86 3 BP GO:0030852 regulation of granulocyte differentiation 3/363 15/17381 0.00341066412966312 0.0172737377179197 0.0125778161602328 EVI2B/INPP5D/C1QC 3 BP GO:0050765 negative regulation of phagocytosis 3/363 15/17381 0.00341066412966312 0.0172737377179197 0.0125778161602328 TLR2/CD300LF/CD300A 3 BP GO:2000484 positive regulation of interleukin-8 secretion 3/363 15/17381 0.00341066412966312 0.0172737377179197 0.0125778161602328 TLR2/CD2/CD14 3 BP GO:0032608 interferon-beta production 5/363 49/17381 0.00346900999607628 0.0175394087747286 0.0127712636795945 NLRC3/LILRB1/TLR2/TLR4/IRF1 5 BP GO:0031334 positive regulation of protein complex assembly 12/363 232/17381 0.00360995223499626 0.0182210809420659 0.0132676210599327 WAS/GBP5/IRF8/GMFG/HCK/LCP1/PTK2B/EVL/TLR4/CCR7/NCKAP1L/CORO1A 12 BP GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 10/363 174/17381 0.0036540177018651 0.0184122922439158 0.013406850949937 CD74/SEMA4D/CSF1R/CD3E/PTK2B/CD4/CD40/CCL5/IL15/TREM2 10 BP GO:0033028 myeloid cell apoptotic process 4/363 31/17381 0.00377060948618324 0.0189041102059942 0.0137649666057573 CLEC5A/PIK3CD/FCER1G/CCL5 4 BP GO:2000404 regulation of T cell migration 4/363 31/17381 0.00377060948618324 0.0189041102059942 0.0137649666057573 DOCK8/AIF1/CXCL10/CCL5 4 BP GO:0035821 modification of morphology or physiology of other organism 9/363 147/17381 0.00377520052235175 0.0189041102059942 0.0137649666057573 LYZ/GNLY/PRF1/CCL13/CD4/CCL3/APOE/CCL5/CCL4 9 BP GO:0002763 positive regulation of myeloid leukocyte differentiation 5/363 50/17381 0.00378970913128896 0.0189041102059942 0.0137649666057573 CD74/EVI2B/CCR1/CSF1/CD4 5 BP GO:0034113 heterotypic cell-cell adhesion 5/363 50/17381 0.00378970913128896 0.0189041102059942 0.0137649666057573 LILRB2/CD2/ITGAX/ITGB7/ITGB2 5 BP GO:0045123 cellular extravasation 5/363 50/17381 0.00378970913128896 0.0189041102059942 0.0137649666057573 SELPLG/PIK3CD/ITGB7/ITGB2/JAML 5 BP GO:0002295 T-helper cell lineage commitment 3/363 16/17381 0.00413332504967391 0.0205150699965482 0.0149379817584706 BATF/SLAMF6/IL12RB1 3 BP GO:0032816 positive regulation of natural killer cell activation 3/363 16/17381 0.00413332504967391 0.0205150699965482 0.0149379817584706 FLT3LG/RASGRP1/IL15 3 BP GO:0045072 regulation of interferon-gamma biosynthetic process 3/363 16/17381 0.00413332504967391 0.0205150699965482 0.0149379817584706 EBI3/LILRB1/FOXP3 3 BP GO:0032642 regulation of chemokine production 6/363 73/17381 0.00418247052137815 0.0207244545967789 0.0150904444768176 MCOLN2/TLR2/CD74/HAVCR2/CSF1R/TLR4 6 BP GO:0002711 positive regulation of T cell mediated immunity 4/363 32/17381 0.00423936899736231 0.0209714964686793 0.0152703272155383 FOXP3/HLA-E/IL12RB1/SASH3 4 BP GO:0038095 Fc-epsilon receptor signaling pathway 10/363 179/17381 0.00446254647589053 0.022038911119738 0.0160475617357677 LCP2/PSMB10/PSME2/VAV1/LAT2/BTK/FCER1G/PSMB9/PSME1/PLCG2 10 BP GO:0046209 nitric oxide metabolic process 6/363 74/17381 0.0044733430187978 0.0220556548178474 0.016059753605304 TLR2/AIF1/ITGB2/PTK2B/TLR4/ACP5 6 BP GO:1903428 positive regulation of reactive oxygen species biosynthetic process 5/363 52/17381 0.00449388154715784 0.0221202962767538 0.0161068220741977 AIF1/ITGB2/PTK2B/TLR4/RAB27A 5 BP GO:0046578 regulation of Ras protein signal transduction 11/363 209/17381 0.00459243957271859 0.0225681271411815 0.016432908667362 FGD2/PREX1/ARHGEF6/VAV1/FGD3/CSF1/RASGRP1/ARHGDIB/RASAL3/APOE/CYTH4 11 BP GO:0002920 regulation of humoral immune response 8/363 125/17381 0.00474429128406829 0.0231694134549564 0.0168707333488425 SERPING1/PTPN6/C3AR1/C1QA/CCR7/C1QC/C5AR1/C1QB 8 BP GO:0032479 regulation of type I interferon production 8/363 125/17381 0.00474429128406829 0.0231694134549564 0.0168707333488425 NLRC3/LILRB1/TLR2/HAVCR2/CD14/TLR4/PLCG2/IRF1 8 BP GO:0045622 regulation of T-helper cell differentiation 4/363 33/17381 0.00474591746390981 0.0231694134549564 0.0168707333488425 FOXP3/JAK3/IL12RB1/CD86 4 BP GO:0098751 bone cell development 4/363 33/17381 0.00474591746390981 0.0231694134549564 0.0168707333488425 LILRB1/PTPN6/TYROBP/FLI1 4 BP GO:0000768 syncytium formation by plasma membrane fusion 5/363 53/17381 0.00487878141943523 0.0237229921958942 0.0172738199157124 CXCL9/FLT3LG/CXCL10/PLEKHO1/CD53 5 BP GO:0045071 negative regulation of viral genome replication 5/363 53/17381 0.00487878141943523 0.0237229921958942 0.0172738199157124 APOBEC3C/APOBEC3D/APOBEC3G/APOBEC3H/CCL5 5 BP GO:0043270 positive regulation of ion transport 12/363 241/17381 0.00488320826597821 0.0237229921958942 0.0172738199157124 CXCL9/CTSS/CCR1/CXCL11/CXCL10/CD4/CCL3/TRPV2/APOE/CCL5/CCL4/PLCG2 12 BP GO:0033630 positive regulation of cell adhesion mediated by integrin 3/363 17/17381 0.00494210125434067 0.0238921713237443 0.0173970071495929 PTPN6/NCKAP1L/CCL5 3 BP GO:0042095 interferon-gamma biosynthetic process 3/363 17/17381 0.00494210125434067 0.0238921713237443 0.0173970071495929 EBI3/LILRB1/FOXP3 3 BP GO:0051023 regulation of immunoglobulin secretion 3/363 17/17381 0.00494210125434067 0.0238921713237443 0.0173970071495929 HLA-E/TNFRSF4/CD40 3 BP GO:0032606 type I interferon production 8/363 126/17381 0.00497638441688939 0.0240189186280334 0.0174892977886073 NLRC3/LILRB1/TLR2/HAVCR2/CD14/TLR4/PLCG2/IRF1 8 BP GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 12/363 243/17381 0.00520979047858997 0.0251047832447264 0.0182799665915437 NLRC3/TLR2/CD74/CARD16/S100B/CD27/TLR4/CASP1/CD4/CCR7/CD40/APOL3 12 BP GO:1903409 reactive oxygen species biosynthetic process 7/363 101/17381 0.00525314044706207 0.02527278231236 0.0184022945684004 CYBB/AIF1/ITGB2/PTK2B/TLR4/RAB27A/ACP5 7 BP GO:0009620 response to fungus 5/363 54/17381 0.00528650042809999 0.0253349758976042 0.018447580626017 COTL1/GNLY/BTK/TLR4/CD86 5 BP GO:0002701 negative regulation of production of molecular mediator of immune response 4/363 34/17381 0.00529158999607449 0.0253349758976042 0.018447580626017 CD96/LILRB1/FOXP3/JAK3 4 BP GO:0072529 pyrimidine-containing compound catabolic process 4/363 34/17381 0.00529158999607449 0.0253349758976042 0.018447580626017 TYMP/APOBEC3C/APOBEC3G/APOBEC3H 4 BP GO:0007260 tyrosine phosphorylation of STAT protein 6/363 77/17381 0.00543552642626473 0.0259407014381673 0.0188886377161021 CSF1R/SOCS1/JAK3/CD40/CCL5/IL15 6 BP GO:2001057 reactive nitrogen species metabolic process 6/363 77/17381 0.00543552642626473 0.0259407014381673 0.0188886377161021 TLR2/AIF1/ITGB2/PTK2B/TLR4/ACP5 6 BP GO:0006949 syncytium formation 5/363 55/17381 0.00571773899026741 0.027200362161368 0.0198058555909717 CXCL9/FLT3LG/CXCL10/PLEKHO1/CD53 5 BP GO:0033627 cell adhesion mediated by integrin 5/363 55/17381 0.00571773899026741 0.027200362161368 0.0198058555909717 FERMT3/PTPN6/LPXN/NCKAP1L/CCL5 5 BP GO:0032928 regulation of superoxide anion generation 3/363 18/17381 0.00583971056068563 0.0276921306524233 0.0201639352246269 ITGAM/ITGB2/ACP5 3 BP GO:0050860 negative regulation of T cell receptor signaling pathway 3/363 18/17381 0.00583971056068563 0.0276921306524233 0.0201639352246269 GBP1/PTPN6/LILRB4 3 BP GO:0006898 receptor-mediated endocytosis 15/363 343/17381 0.00587441433121758 0.0278124099815039 0.0202515162284465 LILRB1/STAB1/APOC1/CD163/MSR1/APOBR/CD14/ITGB2/MRC1/APOE/FCER1G/FOLR2/CD5/PLCG2/CD6 15 BP GO:0033238 regulation of cellular amine metabolic process 6/363 79/17381 0.00615588893696697 0.0290526739370644 0.0211546104097956 ITGAM/PSMB10/PSME2/SLC7A7/PSMB9/PSME1 6 BP GO:0046849 bone remodeling 6/363 79/17381 0.00615588893696697 0.0290526739370644 0.0211546104097956 RAC2/CSF1R/INPP5D/CD38/PTK2B/ACP5 6 BP GO:0034381 plasma lipoprotein particle clearance 5/363 56/17381 0.00617319081689669 0.029088231412529 0.0211805014703651 APOC1/MSR1/APOBR/LIPA/APOE 5 BP GO:0051222 positive regulation of protein transport 19/363 482/17381 0.00630482246475543 0.0296615502370326 0.0215979617151346 CLEC5A/RAC2/TLR2/ITGAM/HAVCR2/CD2/FGR/CSF1R/ITGAX/CD38/CD14/RASGRP1/HLA-E/CD27/TLR4/CASP1/CCL3/TNFRSF4/CD274 19 BP GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism 11/363 219/17381 0.00647676018526768 0.0304223845926296 0.0221519607864045 IRF8/APOBEC3C/CD74/APOBEC3D/APOBEC3G/CD4/CCL3/APOE/APOBEC3H/CCL5/CCL4 11 BP GO:0002720 positive regulation of cytokine production involved in immune response 4/363 36/17381 0.00650545683414241 0.0305090558300411 0.0222150701671502 CD74/TLR4/FCER1G/SASH3 4 BP GO:0032602 chemokine production 6/363 80/17381 0.00654102006550832 0.0306276065331506 0.0223013924775689 MCOLN2/TLR2/CD74/HAVCR2/CSF1R/TLR4 6 BP GO:0002637 regulation of immunoglobulin production 5/363 57/17381 0.00665354209226072 0.0309597630480506 0.022543251167857 FOXP3/HLA-E/TNFRSF4/CD40/SASH3 5 BP GO:0035722 interleukin-12-mediated signaling pathway 5/363 57/17381 0.00665354209226072 0.0309597630480506 0.022543251167857 EBI3/PSME2/STAT4/LCP1/IL12RB1 5 BP GO:0046847 filopodium assembly 5/363 57/17381 0.00665354209226072 0.0309597630480506 0.022543251167857 FGD2/PPP1R16B/FGD3/CCR7/TRPM2 5 BP GO:0071349 cellular response to interleukin-12 5/363 57/17381 0.00665354209226072 0.0309597630480506 0.022543251167857 EBI3/PSME2/STAT4/LCP1/IL12RB1 5 BP GO:0008064 regulation of actin polymerization or depolymerization 9/363 161/17381 0.00680161247417201 0.031599379014172 0.0230089854615229 WAS/PREX1/GMFG/HCK/PTK2B/EVL/CCR7/NCKAP1L/CORO1A 9 BP GO:0043011 myeloid dendritic cell differentiation 3/363 19/17381 0.00682858387838743 0.0316260074492034 0.0230283748702269 SPI1/BATF/CD86 3 BP GO:1901741 positive regulation of myoblast fusion 3/363 19/17381 0.00682858387838743 0.0316260074492034 0.0230283748702269 CXCL9/FLT3LG/CD53 3 BP GO:1903426 regulation of reactive oxygen species biosynthetic process 6/363 81/17381 0.00694334975539935 0.0321076018192225 0.0233790462506091 AIF1/ITGB2/PTK2B/TLR4/RAB27A/ACP5 6 BP GO:0030832 regulation of actin filament length 9/363 162/17381 0.00707340027764947 0.0326582729098297 0.0237800156213103 WAS/PREX1/GMFG/HCK/PTK2B/EVL/CCR7/NCKAP1L/CORO1A 9 BP GO:0070671 response to interleukin-12 5/363 58/17381 0.00715947068195427 0.033004494877492 0.0240321160254616 EBI3/PSME2/STAT4/LCP1/IL12RB1 5 BP GO:0042092 type 2 immune response 4/363 37/17381 0.00717612543978941 0.0330301415142084 0.0240507905409032 CD74/BATF/IDO1/CD86 4 BP GO:0050792 regulation of viral process 10/363 192/17381 0.00723216765805661 0.033236721119896 0.0242012108115605 APOBEC3C/CD74/APOBEC3D/APOBEC3G/CD4/CCL3/APOE/APOBEC3H/CCL5/CCL4 10 BP GO:0045428 regulation of nitric oxide biosynthetic process 5/363 59/17381 0.00769164536985663 0.0352938673519769 0.0256991151762301 AIF1/ITGB2/PTK2B/TLR4/ACP5 5 BP GO:0060191 regulation of lipase activity 6/363 83/17381 0.00780129021279596 0.0357419111595483 0.0260253568232545 APOC1/CCL5/PLCB2/NR1H3/S1PR4/C5AR1 6 BP GO:0002756 MyD88-independent toll-like receptor signaling pathway 4/363 38/17381 0.00789086376576727 0.0360413992246241 0.0262434280876341 CD300LF/CD14/TLR4/LY96 4 BP GO:0050691 regulation of defense response to virus by host 4/363 38/17381 0.00789086376576727 0.0360413992246241 0.0262434280876341 LILRB1/APOBEC3G/IL12RB1/IL15 4 BP GO:0050710 negative regulation of cytokine secretion 5/363 60/17381 0.00825072512437684 0.0376273498015226 0.0273982328624426 LILRB1/CARD16/GBP1/SRGN/FOXP3 5 BP GO:0043254 regulation of protein complex assembly 16/363 392/17381 0.0085582950793804 0.0389703405908178 0.0283761272549873 WAS/GBP5/IRF8/NLRC3/PREX1/TMC8/GMFG/HCK/LCP1/PTK2B/EVL/TLR4/CCR7/NCKAP1L/APOE/CORO1A 16 BP GO:0002639 positive regulation of immunoglobulin production 4/363 39/17381 0.0086508021479544 0.0393314332772644 0.028639055724847 HLA-E/TNFRSF4/CD40/SASH3 4 BP GO:0032535 regulation of cellular component size 14/363 325/17381 0.00867003341024445 0.039358779719067 0.0286589679478555 WAS/PREX1/SEMA4D/VAV1/GMFG/HCK/PTK2B/EVL/IL7R/CCR7/NCKAP1L/TRPV2/APOE/CORO1A 14 BP GO:0006521 regulation of cellular amino acid metabolic process 5/363 61/17381 0.0088373583942264 0.0399964335835961 0.0291232735436033 PSMB10/PSME2/SLC7A7/PSMB9/PSME1 5 BP GO:0060193 positive regulation of lipase activity 5/363 61/17381 0.0088373583942264 0.0399964335835961 0.0291232735436033 CCL5/PLCB2/NR1H3/S1PR4/C5AR1 5 BP GO:0043032 positive regulation of macrophage activation 3/363 21/17381 0.00908849236165913 0.0410706073642199 0.0299054297021289 ITGAM/HAVCR2/TLR4 3 BP GO:1903169 regulation of calcium ion transmembrane transport 8/363 142/17381 0.00999857611731737 0.0450649152640375 0.0328138720596364 CXCL9/CLIC2/PTPN6/PTK2B/CXCL11/CXCL10/CORO1A/PLCG2 8 BP GO:0019935 cyclic-nucleotide-mediated signaling 7/363 114/17381 0.0100026558057518 0.0450649152640375 0.0328138720596364 CXCL9/PTK2B/GNG2/CXCL11/CXCL10/APOE/S1PR4 7 BP GO:0002544 chronic inflammatory response 3/363 22/17381 0.0103630741633128 0.0464777633408817 0.0338426328098039 IDO1/FOXP3/CCL5 3 BP GO:0043949 regulation of cAMP-mediated signaling 3/363 22/17381 0.0103630741633128 0.0464777633408817 0.0338426328098039 CXCL9/CXCL11/CXCL10 3 BP GO:0061082 myeloid leukocyte cytokine production 3/363 22/17381 0.0103630741633128 0.0464777633408817 0.0338426328098039 CD74/TLR4/FCER1G 3 BP GO:0097006 regulation of plasma lipoprotein particle levels 6/363 89/17381 0.0108312317003754 0.0485043729379216 0.0353183020225932 APOC1/MSR1/APOBR/LIPA/APOE/PLA2G7 6 BP GO:0043902 positive regulation of multi-organism process 9/363 174/17381 0.0110229771618437 0.0492889279098658 0.0358895731838124 LY86/CD74/HAVCR2/LHFPL2/PRF1/CD4/APOE/CCL5/LY96 9 BP GO:0043551 regulation of phosphatidylinositol 3-kinase activity 4/363 42/17381 0.0112124438398397 0.0498368026194665 0.0362885063787427 FGR/PTK2B/CCR7/PIK3R5 4 BP GO:0045429 positive regulation of nitric oxide biosynthetic process 4/363 42/17381 0.0112124438398397 0.0498368026194665 0.0362885063787427 AIF1/ITGB2/PTK2B/TLR4 4 BP GO:0097300 programmed necrotic cell death 4/363 42/17381 0.0112124438398397 0.0498368026194665 0.0362885063787427 CD14/TLR4/CASP1/LY96 4 BP GO:1904407 positive regulation of nitric oxide metabolic process 4/363 42/17381 0.0112124438398397 0.0498368026194665 0.0362885063787427 AIF1/ITGB2/PTK2B/TLR4 4 CC GO:0098552 side of membrane 66/385 482/18511 4.48944827038084e-35 1.24357717089549e-32 8.50632303861633e-33 CD79B/SLA/CXCL9/FLT3LG/ZAP70/LILRB1/CD69/CD74/RGS1/RGS19/GNGT2/LAG3/FCGR3A/ITGAM/HLA-DRB1/KCNAB2/CTLA4/CD163/PTPRC/HLA-DQB1/HLA-DPA1/ITGAE/CD2/FGR/PDCD1/CXCR3/CD8A/IL2RB/HCK/HLA-DQB2/SPN/CD14/PTPN7/CD3E/ITGB2/BTK/CCR1/PTK2B/GNG2/HLA-DRA/HLA-E/HLA-DQA1/RASAL3/CD27/CXCL10/IL7R/LCK/TLR4/CD4/CCR7/FCER1G/JAK3/CD40/IL12RB1/HLA-DPB1/CCR5/FOLR2/CD274/HLA-DRB5/IL2RA/SELL/CD5/IL2RG/CD86/SLA2/HLA-DQA2 66 CC GO:0009897 external side of plasma membrane 40/385 270/18511 1.01020503014197e-22 1.39913396674662e-20 9.57036344345021e-21 CD79B/CXCL9/FLT3LG/LILRB1/CD69/CD74/LAG3/FCGR3A/ITGAM/CTLA4/CD163/PTPRC/ITGAE/CD2/PDCD1/CXCR3/CD8A/IL2RB/SPN/CD14/CD3E/ITGB2/CCR1/CD27/CXCL10/IL7R/TLR4/CD4/CCR7/FCER1G/CD40/IL12RB1/CCR5/FOLR2/CD274/IL2RA/SELL/CD5/IL2RG/CD86 40 CC GO:0042613 MHC class II protein complex 13/385 16/18511 5.90073158095667e-20 5.44834215974999e-18 3.72677784060421e-18 CD74/HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DPA1/HLA-DQB2/HLA-DRA/HLA-DQA1/HLA-DPB1/HLA-DRB5/HLA-DMB/HLA-DOA/HLA-DQA2 13 CC GO:0030667 secretory granule membrane 37/385 301/18511 2.74861411239295e-18 1.90341527283212e-16 1.30197510587034e-16 CLEC5A/LAIR1/NFAM1/TLR2/PSAP/ITGAM/KCNAB2/FCGR2A/TNFRSF1B/STK10/LILRB2/PTPRC/MMP25/GPR84/DOK3/CYBB/ITGAX/C3AR1/CD14/TBC1D10C/LHFPL2/ITGB2/CD300A/TYROBP/ITGAL/FPR1/NCKAP1L/HVCN1/FCER1G/CD53/TRPM2/SELL/RAB27A/SLC2A5/C5AR1/RHOG/SLC11A1 37 CC GO:0042611 MHC protein complex 14/385 25/18511 8.1192139693854e-18 4.49804453903951e-16 3.07675476734605e-16 CD74/HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DPA1/HLA-DQB2/HLA-DRA/HLA-E/HLA-DQA1/HLA-DPB1/HLA-DRB5/HLA-DMB/HLA-DOA/HLA-DQA2 14 CC GO:0042101 T cell receptor complex 10/385 19/18511 1.05459473906228e-12 4.86871237867087e-11 3.33029917598616e-11 ZAP70/CD3D/CD247/PTPN6/CD8A/CD3E/CD3G/CD4/APBB1IP/CD6 10 CC GO:0042581 specific granule 22/385 160/18511 2.41014229024927e-12 9.53727734855784e-11 6.52369341721608e-11 LYZ/CLEC5A/LAIR1/DOCK2/ITGAM/KCNAB2/TNFRSF1B/STK10/MMP25/GPR84/PTPN6/CYBB/OSCAR/C3AR1/ITGB2/CTSZ/ITGAL/HVCN1/CD53/TRPM2/RAB27A/SLC2A5 22 CC GO:0070820 tertiary granule 22/385 164/18511 3.99742044690405e-12 1.38410682974053e-10 9.46757474266747e-11 LYZ/CLEC5A/LAIR1/ITGAM/KCNAB2/LILRB2/GPR84/DOK3/PTPN6/CTSS/CYBB/OSCAR/ITGAX/TBC1D10C/ITGB2/CD300A/FPR1/NCKAP1L/FCER1G/CD53/TRPM2/SLC11A1 22 CC GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane 11/385 29/18511 6.75986536985478e-12 1.87248270744977e-10 1.28081659639354e-10 CD74/HLA-DRB1/HLA-DQB1/HLA-DPA1/HLA-DQB2/HLA-DRA/HLA-E/HLA-DQA1/HLA-DPB1/HLA-DRB5/HLA-DQA2 11 CC GO:0098553 lumenal side of endoplasmic reticulum membrane 11/385 29/18511 6.75986536985478e-12 1.87248270744977e-10 1.28081659639354e-10 CD74/HLA-DRB1/HLA-DQB1/HLA-DPA1/HLA-DQB2/HLA-DRA/HLA-E/HLA-DQA1/HLA-DPB1/HLA-DRB5/HLA-DQA2 11 CC GO:0098797 plasma membrane protein complex 25/385 241/18511 4.31189046922192e-11 1.08581241815861e-09 7.42717975559756e-10 CD79B/CD74/RGS19/GNGT2/ITGAM/HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DPA1/ITGAE/ITGAX/ITGB7/HLA-DQB2/ITGB2/GNG2/HLA-DRA/HLA-E/HLA-DQA1/ITGAL/FCER1G/HLA-DPB1/HLA-DRB5/HLA-DMB/HLA-DOA/HLA-DQA2 25 CC GO:0035579 specific granule membrane 16/385 91/18511 5.66018169071581e-11 1.30655860694023e-09 8.93712898534075e-10 CLEC5A/LAIR1/ITGAM/KCNAB2/TNFRSF1B/STK10/MMP25/GPR84/CYBB/C3AR1/ITGB2/ITGAL/HVCN1/CD53/TRPM2/SLC2A5 16 CC GO:0098802 plasma membrane receptor complex 21/385 177/18511 1.31522947466868e-10 2.8024504960248e-09 1.91693364729038e-09 CD79B/ZAP70/TLR2/CD3D/ITGAM/ITGAE/CD247/PTPN6/CD8A/ITGAX/ITGB7/CD3E/ITGB2/PTK2B/CD3G/ITGAL/CD4/CD40/IL12RB1/APBB1IP/CD6 21 CC GO:0070821 tertiary granule membrane 14/385 73/18511 2.72211448470763e-10 5.38589794474296e-09 3.68406471614567e-09 CLEC5A/LAIR1/ITGAM/KCNAB2/LILRB2/GPR84/CYBB/ITGAX/ITGB2/CD300A/FCER1G/CD53/TRPM2/SLC11A1 14 CC GO:0030666 endocytic vesicle membrane 20/385 169/18511 3.81943404811789e-10 7.05322154219103e-09 4.8245482713068e-09 RAC2/TLR2/CD74/STAB1/HLA-DRB1/CD163/HLA-DQB1/MSR1/HLA-DPA1/CYBB/HLA-DQB2/HLA-DRA/HLA-E/HLA-DQA1/APOE/CORO1A/HLA-DPB1/HLA-DRB5/SLC11A1/HLA-DQA2 20 CC GO:0001772 immunological synapse 10/385 33/18511 8.14817147056877e-10 1.41065218584222e-08 9.64915042567354e-09 ZAP70/GZMA/HAVCR2/CD3E/LCK/CORO1A/CD53/CD37/GZMB/CD6 10 CC GO:0043235 receptor complex 27/385 325/18511 1.10270577556751e-09 1.79676176371882e-08 1.22902191704119e-08 CD79B/ZAP70/TLR2/CD74/CD3D/ITGAM/GPR84/ITGAE/CD247/PTPN6/CD8A/ITGAX/ITGB7/CD14/CD3E/ITGB2/PTK2B/CD3G/TLR4/ITGAL/CD4/CD40/IL12RB1/APBB1IP/NR1H3/LY96/CD6 27 CC GO:0101002 ficolin-1-rich granule 20/385 185/18511 1.91168928466039e-09 2.94187739917182e-08 2.01230451016883e-08 PLEKHO2/COTL1/BIN2/LILRB2/MNDA/DOK3/CTSS/FGL2/ITGAX/GMFG/TBC1D10C/ITGB2/CTSZ/CD300A/FPR1/NCKAP1L/FCER1G/TRPM2/SLC11A1/HK3 20 CC GO:0030139 endocytic vesicle 24/385 277/18511 4.15767362425451e-09 6.06145049430789e-08 4.14615652280228e-08 RAC2/TLR2/CD74/STAB1/HLA-DRB1/CTLA4/CD163/HLA-DQB1/NCF4/MSR1/HLA-DPA1/GNLY/CYBB/HLA-DQB2/FMNL1/HLA-DRA/HLA-E/HLA-DQA1/APOE/CORO1A/HLA-DPB1/HLA-DRB5/SLC11A1/HLA-DQA2 24 CC GO:0030669 clathrin-coated endocytic vesicle membrane 11/385 51/18511 6.17262605821707e-09 8.54908709063064e-08 5.84775100252143e-08 CD74/HLA-DRB1/HLA-DQB1/HLA-DPA1/HLA-DQB2/HLA-DRA/HLA-DQA1/APOE/HLA-DPB1/HLA-DRB5/HLA-DQA2 11 CC GO:0045334 clathrin-coated endocytic vesicle 12/385 70/18511 1.98289936088634e-08 2.61553868078817e-07 1.78908213012301e-07 CD74/HLA-DRB1/CTLA4/HLA-DQB1/HLA-DPA1/HLA-DQB2/HLA-DRA/HLA-DQA1/APOE/HLA-DPB1/HLA-DRB5/HLA-DQA2 12 CC GO:0012507 ER to Golgi transport vesicle membrane 11/385 59/18511 3.12502037749057e-08 3.91372161910229e-07 2.67706589944295e-07 CD74/HLA-DRB1/HLA-DQB1/HLA-DPA1/HLA-DQB2/HLA-DRA/HLA-E/HLA-DQA1/HLA-DPB1/HLA-DRB5/HLA-DQA2 11 CC GO:0030136 clathrin-coated vesicle 18/385 177/18511 3.24966055015713e-08 3.91372161910229e-07 2.67706589944295e-07 CD74/RGS19/CD3D/HLA-DRB1/CTLA4/HLA-DQB1/HLA-DPA1/HLA-DQB2/DENND1C/HLA-DRA/HLA-DQA1/CD3G/CD4/APOE/HLA-DPB1/HLA-DRB5/RAB27A/HLA-DQA2 18 CC GO:0101003 ficolin-1-rich granule membrane 11/385 61/18511 4.49772625528456e-08 5.19112571964093e-07 3.55083651732991e-07 LILRB2/DOK3/ITGAX/TBC1D10C/ITGB2/CD300A/FPR1/NCKAP1L/FCER1G/TRPM2/SLC11A1 11 CC GO:0030665 clathrin-coated vesicle membrane 14/385 107/18511 4.71956270676605e-08 5.22927547909679e-07 3.57693173565427e-07 CD74/CD3D/HLA-DRB1/HLA-DQB1/HLA-DPA1/HLA-DQB2/HLA-DRA/HLA-DQA1/CD3G/CD4/APOE/HLA-DPB1/HLA-DRB5/HLA-DQA2 14 CC GO:0031234 extrinsic component of cytoplasmic side of plasma membrane 14/385 108/18511 5.32138650683589e-08 5.66932331689824e-07 3.877933486763e-07 SLA/ZAP70/RGS1/RGS19/GNGT2/KCNAB2/FGR/HCK/BTK/PTK2B/GNG2/LCK/JAK3/SLA2 14 CC GO:0030134 COPII-coated ER to Golgi transport vesicle 12/385 78/18511 6.96980864888427e-08 7.15050739163312e-07 4.89109378869072e-07 CD74/HLA-DRB1/HLA-DQB1/HLA-DPA1/HLA-DQB2/CTSZ/HLA-DRA/HLA-E/HLA-DQA1/HLA-DPB1/HLA-DRB5/HLA-DQA2 12 CC GO:0009898 cytoplasmic side of plasma membrane 17/385 170/18511 1.0050467442639e-07 9.94278386289642e-07 6.80106819426698e-07 SLA/ZAP70/RGS1/RGS19/GNGT2/KCNAB2/CD2/FGR/HCK/PTPN7/BTK/PTK2B/GNG2/RASAL3/LCK/JAK3/SLA2 17 CC GO:0044440 endosomal part 30/385 484/18511 1.11418394758077e-07 1.06423777062025e-06 7.2796047391847e-07 MCOLN2/ACAP1/FGD2/HLA-DRB1/HLA-DMA/HLA-DQB1/NCF4/HLA-DPA1/CTSS/HLA-DQB2/CD14/PRF1/HLA-DRA/MRC1/HLA-E/HLA-DQA1/TLR4/MARCH1/HLA-DPB1/LGMN/HLA-DRB5/SNX10/RAB27A/LY96/SLA2/HLA-DMB/SLC11A1/HLA-DOA/HLA-DQA2/SNX20 30 CC GO:0098562 cytoplasmic side of membrane 17/385 189/18511 4.63005277675845e-07 4.27508206387364e-06 2.92424385900534e-06 SLA/ZAP70/RGS1/RGS19/GNGT2/KCNAB2/CD2/FGR/HCK/PTPN7/BTK/PTK2B/GNG2/RASAL3/LCK/JAK3/SLA2 17 CC GO:0030135 coated vesicle 20/385 262/18511 6.44253383267627e-07 5.63269092135958e-06 3.85287617649525e-06 CD74/RGS19/CD3D/HLA-DRB1/CTLA4/HLA-DQB1/HLA-DPA1/HLA-DQB2/DENND1C/CTSZ/HLA-DRA/HLA-E/HLA-DQA1/CD3G/CD4/APOE/HLA-DPB1/HLA-DRB5/RAB27A/HLA-DQA2 20 CC GO:0010008 endosome membrane 27/385 442/18511 6.50707976474753e-07 5.63269092135958e-06 3.85287617649525e-06 MCOLN2/ACAP1/FGD2/HLA-DRB1/HLA-DMA/HLA-DQB1/NCF4/HLA-DPA1/HLA-DQB2/CD14/HLA-DRA/MRC1/HLA-E/HLA-DQA1/TLR4/MARCH1/HLA-DPB1/HLA-DRB5/SNX10/RAB27A/LY96/SLA2/HLA-DMB/SLC11A1/HLA-DOA/HLA-DQA2/SNX20 27 CC GO:0005765 lysosomal membrane 23/385 349/18511 1.23902678215458e-06 1.00944240781418e-05 6.90479321324536e-06 MCOLN2/NFAM1/CD74/PSAP/HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DPA1/MYO7A/C3AR1/HLA-DQB2/HLA-DRA/HLA-DQA1/LAPTM5/FPR1/MARCH1/HLA-DPB1/HLA-DRB5/TRPM2/ACP2/HLA-DMB/HLA-DOA/HLA-DQA2 23 CC GO:0098852 lytic vacuole membrane 23/385 349/18511 1.23902678215458e-06 1.00944240781418e-05 6.90479321324536e-06 MCOLN2/NFAM1/CD74/PSAP/HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DPA1/MYO7A/C3AR1/HLA-DQB2/HLA-DRA/HLA-DQA1/LAPTM5/FPR1/MARCH1/HLA-DPB1/HLA-DRB5/TRPM2/ACP2/HLA-DMB/HLA-DOA/HLA-DQA2 23 CC GO:0032588 trans-Golgi network membrane 11/385 84/18511 1.30275588925477e-06 1.03103823235306e-05 7.05251308468745e-06 CD74/HLA-DRB1/HLA-DQB1/HLA-DPA1/HLA-DQB2/HLA-DRA/HLA-DQA1/MARCH1/HLA-DPB1/HLA-DRB5/HLA-DQA2 11 CC GO:0045121 membrane raft 21/385 301/18511 1.46374200535454e-06 1.12626815412002e-05 7.70390529133969e-06 ZAP70/NFAM1/TLR2/RGS19/ITGAM/LCP2/TNFRSF1B/CD48/PTPRC/LAT2/CD8A/SELPLG/INPP5D/HCK/PAG1/CD14/ITGB2/BTK/PTK2B/LCK/CD4 21 CC GO:0098857 membrane microdomain 21/385 302/18511 1.54356915547249e-06 1.15559096234021e-05 7.90447931678656e-06 ZAP70/NFAM1/TLR2/RGS19/ITGAM/LCP2/TNFRSF1B/CD48/PTPRC/LAT2/CD8A/SELPLG/INPP5D/HCK/PAG1/CD14/ITGB2/BTK/PTK2B/LCK/CD4 21 CC GO:0060205 cytoplasmic vesicle lumen 22/385 338/18511 2.59126631079238e-06 1.8422830919546e-05 1.26015943968014e-05 LYZ/COTL1/DOCK2/BIN2/FERMT3/SERPING1/ADA2/CTSW/ARHGAP45/MNDA/FGR/GNLY/PTPN6/OSCAR/SRGN/GMFG/ARHGAP9/CTSZ/MAN2B1/APOE/RAB27A/HK3 22 CC GO:0030662 coated vesicle membrane 15/385 169/18511 2.59382818000828e-06 1.8422830919546e-05 1.26015943968014e-05 CD74/CD3D/HLA-DRB1/HLA-DQB1/HLA-DPA1/HLA-DQB2/HLA-DRA/HLA-E/HLA-DQA1/CD3G/CD4/APOE/HLA-DPB1/HLA-DRB5/HLA-DQA2 15 CC GO:0031983 vesicle lumen 22/385 339/18511 2.71900443165823e-06 1.88291056892332e-05 1.28794946762758e-05 LYZ/COTL1/DOCK2/BIN2/FERMT3/SERPING1/ADA2/CTSW/ARHGAP45/MNDA/FGR/GNLY/PTPN6/OSCAR/SRGN/GMFG/ARHGAP9/CTSZ/MAN2B1/APOE/RAB27A/HK3 22 CC GO:0019897 extrinsic component of plasma membrane 14/385 151/18511 3.350552384857e-06 2.26366587952534e-05 1.54839391341273e-05 SLA/ZAP70/RGS1/RGS19/GNGT2/KCNAB2/FGR/HCK/BTK/PTK2B/GNG2/LCK/JAK3/SLA2 14 CC GO:0042629 mast cell granule 6/385 22/18511 4.38116503866049e-06 2.8894826564499e-05 1.97646543097466e-05 MILR1/LAT2/SRGN/PIK3CD/BTK/RASGRP1 6 CC GO:0001891 phagocytic cup 6/385 23/18511 5.82395945750129e-06 3.75171341797176e-05 2.56624896536165e-05 BIN2/ARHGAP25/AIF1/LCP1/MYO1G/CORO1A 6 CC GO:0098636 protein complex involved in cell adhesion 7/385 35/18511 6.48586350223519e-06 4.08314588663443e-05 2.7929555751252e-05 ITGAM/CTLA4/ITGAE/ITGAX/ITGB7/ITGB2/ITGAL 7 CC GO:0005774 vacuolar membrane 23/385 398/18511 1.10094819649777e-05 6.77694778733073e-05 4.63557135367483e-05 MCOLN2/NFAM1/CD74/PSAP/HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DPA1/MYO7A/C3AR1/HLA-DQB2/HLA-DRA/HLA-DQA1/LAPTM5/FPR1/MARCH1/HLA-DPB1/HLA-DRB5/TRPM2/ACP2/HLA-DMB/HLA-DOA/HLA-DQA2 23 CC GO:0034774 secretory granule lumen 20/385 321/18511 1.40659667170807e-05 8.35987937476944e-05 5.71832904221357e-05 LYZ/COTL1/DOCK2/BIN2/FERMT3/SERPING1/ADA2/CTSW/ARHGAP45/MNDA/FGR/PTPN6/OSCAR/SRGN/GMFG/ARHGAP9/CTSZ/MAN2B1/RAB27A/HK3 20 CC GO:0030660 Golgi-associated vesicle membrane 11/385 107/18511 1.41846328741575e-05 8.35987937476944e-05 5.71832904221357e-05 CD74/HLA-DRB1/HLA-DQB1/HLA-DPA1/HLA-DQB2/HLA-DRA/HLA-E/HLA-DQA1/HLA-DPB1/HLA-DRB5/HLA-DQA2 11 CC GO:0031252 cell leading edge 21/385 369/18511 3.32244800670405e-05 0.000191732937053546 0.000131149263422528 RAC2/PSTPIP1/FGD2/DOCK8/WIPF1/ARHGAP45/FGR/ARHGEF6/AIF1/LCP1/FGD3/PTK2B/S100B/EVL/ABI3/MYO1G/SAMSN1/CORO1A/PLEKHO1/APBB1IP/CXCR4 21 CC GO:0019898 extrinsic component of membrane 17/385 261/18511 3.54065640036641e-05 0.00020015547406153 0.000136910451571634 SLA/ZAP70/RGS1/RGS19/GNGT2/KCNAB2/FGR/PIK3CD/HCK/BTK/PTK2B/GNG2/LCK/PIK3R5/JAK3/SNX10/SLA2 17 CC GO:0008305 integrin complex 6/385 32/18511 4.46288668397e-05 0.000247243922291938 0.000169119916445179 ITGAM/ITGAE/ITGAX/ITGB7/ITGB2/ITGAL 6 CC GO:0098589 membrane region 21/385 378/18511 4.71300773765836e-05 0.000255981008496346 0.000175096262699382 ZAP70/NFAM1/TLR2/RGS19/ITGAM/LCP2/TNFRSF1B/CD48/PTPRC/LAT2/CD8A/SELPLG/INPP5D/HCK/PAG1/CD14/ITGB2/BTK/PTK2B/LCK/CD4 21 CC GO:0005775 vacuolar lumen 13/385 170/18511 5.82601779696502e-05 0.000310347486492175 0.000212284049282126 LYZ/NAAA/CD74/PSAP/ADA2/ARHGAP45/MNDA/CTSS/MAN2B1/LIPA/LGMN/ACP2/IFI30 13 CC GO:0005802 trans-Golgi network 14/385 197/18511 6.7951508782244e-05 0.000355142791182672 0.000242924956917655 CD74/LAP3/HLA-DRB1/HLA-DQB1/NCF4/HLA-DPA1/HLA-DQB2/HLA-DRA/HLA-DQA1/MARCH1/HLA-DPB1/HLA-DRB5/CORO7/HLA-DQA2 14 CC GO:0005798 Golgi-associated vesicle 12/385 158/18511 0.000119080758451681 0.000610840186872513 0.000417827222637478 CD74/HLA-DRB1/HLA-DQB1/HLA-DPA1/HLA-DQB2/CTSZ/HLA-DRA/HLA-E/HLA-DQA1/HLA-DPB1/HLA-DRB5/HLA-DQA2 12 CC GO:0043202 lysosomal lumen 9/385 93/18511 0.000136866346473206 0.000680214038802471 0.000465280360951719 NAAA/CD74/PSAP/CTSS/MAN2B1/LIPA/LGMN/ACP2/IFI30 9 CC GO:0030027 lamellipodium 13/385 185/18511 0.000137516195570175 0.000680214038802471 0.000465280360951719 RAC2/PSTPIP1/FGD2/DOCK8/ARHGEF6/AIF1/FGD3/PTK2B/EVL/ABI3/MYO1G/CORO1A/APBB1IP 13 CC GO:0034362 low-density lipoprotein particle 4/385 14/18511 0.000156316190063217 0.000759641835921246 0.000519610604088255 MSR1/APOBR/APOE/PLA2G7 4 CC GO:0030176 integral component of endoplasmic reticulum membrane 11/385 143/18511 0.000203234931227228 0.000970621999136935 0.000663925365170618 CD74/HLA-DRB1/HLA-DQB1/HLA-DPA1/HLA-DQB2/HLA-DRA/HLA-E/HLA-DQA1/HLA-DPB1/HLA-DRB5/HLA-DQA2 11 CC GO:0031227 intrinsic component of endoplasmic reticulum membrane 11/385 147/18511 0.000258556031347319 0.00121389865564758 0.000830331590410659 CD74/HLA-DRB1/HLA-DQB1/HLA-DPA1/HLA-DQB2/HLA-DRA/HLA-E/HLA-DQA1/HLA-DPB1/HLA-DRB5/HLA-DQA2 11 CC GO:0045335 phagocytic vesicle 9/385 105/18511 0.000343792120711404 0.00158717362395098 0.00108565932856233 RAC2/TLR2/NCF4/GNLY/CYBB/FMNL1/HLA-E/CORO1A/SLC11A1 9 CC GO:0005770 late endosome 14/385 232/18511 0.000375201785590897 0.00170378515751932 0.00116542401046353 MCOLN2/CD74/HLA-DRB1/HLA-DMA/HLA-DRA/VAMP5/MARCH1/LGMN/HLA-DRB5/RAB27A/SLA2/CXCR4/HLA-DMB/SLC11A1 14 CC GO:0002102 podosome 5/385 32/18511 0.000480756327623038 0.00214789520567067 0.00146920439681064 BIN2/FERMT3/LPXN/NCF1C/LCP1 5 CC GO:0005884 actin filament 8/385 88/18511 0.000491218550456295 0.002159802198038 0.00147734902392871 WAS/RAC2/WIPF1/HCK/AIF1/LCP1/CORO1A/RCSD1 8 CC GO:0031902 late endosome membrane 9/385 124/18511 0.00115045899041865 0.00490272523609179 0.00335356466842684 MCOLN2/HLA-DRB1/HLA-DMA/HLA-DRA/MARCH1/HLA-DRB5/RAB27A/HLA-DMB/SLC11A1 9 CC GO:1904813 ficolin-1-rich granule lumen 9/385 124/18511 0.00115045899041865 0.00490272523609179 0.00335356466842684 PLEKHO2/COTL1/BIN2/MNDA/CTSS/FGL2/GMFG/CTSZ/HK3 9 CC GO:0034358 plasma lipoprotein particle 5/385 39/18511 0.00122024299118455 0.00504488520236001 0.00345080500256432 APOC1/MSR1/APOBR/APOE/PLA2G7 5 CC GO:1990777 lipoprotein particle 5/385 39/18511 0.00122024299118455 0.00504488520236001 0.00345080500256432 APOC1/MSR1/APOBR/APOE/PLA2G7 5 CC GO:0015629 actin cytoskeleton 20/385 457/18511 0.00151264459869517 0.0061618022623318 0.0042147991914107 WAS/RAC2/GBP2/FYB1/BIN2/FERMT3/WIPF1/FGR/MYO7A/MYO1F/HCK/LPXN/AIF1/NCF1C/LCP1/MYO1G/CORO1A/LSP1/STK17B/RCSD1 20 CC GO:0032994 protein-lipid complex 5/385 41/18511 0.00153525347438613 0.00616326394789796 0.00421579901433263 APOC1/MSR1/APOBR/APOE/PLA2G7 5 CC GO:0030658 transport vesicle membrane 11/385 183/18511 0.00160387839462495 0.00634677593301588 0.0043413249779322 CD74/HLA-DRB1/HLA-DQB1/HLA-DPA1/HLA-DQB2/HLA-DRA/HLA-E/HLA-DQA1/HLA-DPB1/HLA-DRB5/HLA-DQA2 11 CC GO:0035580 specific granule lumen 6/385 62/18511 0.00179337506844176 0.00699668864730097 0.0047858786111122 LYZ/DOCK2/PTPN6/OSCAR/CTSZ/RAB27A 6 CC GO:0001726 ruffle 10/385 162/18511 0.00212391735641097 0.00807447668191044 0.00552310774365905 FGD2/WIPF1/ARHGAP45/FGR/AIF1/LCP1/FGD3/S100B/SAMSN1/PLEKHO1 10 CC GO:0001931 uropod 3/385 13/18511 0.00218623014853171 0.00807447668191044 0.00552310774365905 PSTPIP1/SELPLG/SPN 3 CC GO:0031254 cell trailing edge 3/385 13/18511 0.00218623014853171 0.00807447668191044 0.00552310774365905 PSTPIP1/SELPLG/SPN 3 CC GO:0042627 chylomicron 3/385 13/18511 0.00218623014853171 0.00807447668191044 0.00552310774365905 APOC1/APOBR/APOE 3 CC GO:0030670 phagocytic vesicle membrane 6/385 72/18511 0.00383327731324927 0.0139712870496059 0.00955664704134166 RAC2/TLR2/CYBB/HLA-E/CORO1A/SLC11A1 6 CC GO:0005766 primary lysosome 9/385 155/18511 0.0052091884227376 0.0184992973474143 0.0126538990026015 LYZ/NFAM1/PSAP/ADA2/ARHGAP45/MNDA/C3AR1/MAN2B1/FPR1 9 CC GO:0042582 azurophil granule 9/385 155/18511 0.0052091884227376 0.0184992973474143 0.0126538990026015 LYZ/NFAM1/PSAP/ADA2/ARHGAP45/MNDA/C3AR1/MAN2B1/FPR1 9 CC GO:0030133 transport vesicle 15/385 354/18511 0.00752528758101094 0.0263861349359497 0.0180486577559223 SEPT6/STX11/CD74/HLA-DRB1/HLA-DQB1/HLA-DPA1/HCK/HLA-DQB2/HLA-DRA/HLA-E/HLA-DQA1/HLA-DPB1/HLA-DRB5/RAB27A/HLA-DQA2 15 CC GO:0031233 intrinsic component of external side of plasma membrane 3/385 20/18511 0.00782431740643385 0.0264309258729534 0.0180792956759704 FLT3LG/CD14/FOLR2 3 CC GO:0034361 very-low-density lipoprotein particle 3/385 20/18511 0.00782431740643385 0.0264309258729534 0.0180792956759704 APOC1/APOBR/APOE 3 CC GO:0034385 triglyceride-rich plasma lipoprotein particle 3/385 20/18511 0.00782431740643385 0.0264309258729534 0.0180792956759704 APOC1/APOBR/APOE 3 CC GO:0032587 ruffle membrane 6/385 88/18511 0.0100947762099098 0.0336897953029518 0.0230445113225587 FGD2/ARHGAP45/FGR/AIF1/LCP1/PLEKHO1 6 CC GO:0031256 leading edge membrane 8/385 149/18511 0.0128311945012722 0.0423123913910998 0.0289425439878319 FGD2/DOCK8/ARHGAP45/FGR/AIF1/LCP1/MYO1G/PLEKHO1 8 CC GO:0044853 plasma membrane raft 6/385 96/18511 0.0150580895159367 0.0490716564225231 0.033566019973605 ITGAM/LCP2/CD8A/SELPLG/HCK/ITGB2 6 MF GO:0004896 cytokine receptor activity 18/365 91/17354 4.99202119745304e-13 2.27636166603859e-10 1.77610859446224e-10 IL10RA/EBI3/CD74/CXCR3/CXCR6/IL2RB/CCRL2/CCR1/IL7R/CD4/CCR7/IL12RB1/CCR5/CMKLR1/IL2RA/IL2RG/CXCR4/IL15RA 18 MF GO:0032395 MHC class II receptor activity 7/365 10/17354 1.95472983351013e-10 3.03935335645456e-08 2.37142528735374e-08 HLA-DQB1/HLA-DPA1/HLA-DQB2/HLA-DRA/HLA-DQA1/HLA-DOA/HLA-DQA2 7 MF GO:0008009 chemokine activity 12/365 48/17354 2.2070649839553e-10 3.03935335645456e-08 2.37142528735374e-08 CXCL9/CCL4L1/CCL3L1/CCL3L3/CXCL11/CXCL10/CCL13/CCL3/XCL2/CCL5/CCL4/CCL18 12 MF GO:0042379 chemokine receptor binding 13/365 60/17354 2.69732108371612e-10 3.03935335645456e-08 2.37142528735374e-08 CXCL9/CCL4L1/CCL3L1/CCL3L3/CCRL2/CXCL11/CXCL10/CCL13/CCL3/XCL2/CCL5/CCL4/CCL18 13 MF GO:0019955 cytokine binding 16/365 101/17354 3.33262429435807e-10 3.03935335645456e-08 2.37142528735374e-08 IL10RA/IL18BP/CD74/GBP1/CXCR3/CSF1R/CXCR6/IL2RB/CCR1/CD4/CCR7/IL12RB1/CCR5/IL2RA/IL2RG/CXCR4 16 MF GO:0048020 CCR chemokine receptor binding 10/365 39/17354 5.53521547232648e-09 4.20676375896812e-07 3.28228566604623e-07 CCL4L1/CCL3L1/CCL3L3/CCRL2/CCL13/CCL3/XCL2/CCL5/CCL4/CCL18 10 MF GO:0042287 MHC protein binding 9/365 32/17354 1.33578757091116e-08 8.70170189050701e-07 6.78941652583419e-07 PILRA/LILRB1/CD74/LAG3/LILRB2/CD8A/HLA-E/CD4/MARCH1 9 MF GO:0001637 G-protein coupled chemoattractant receptor activity 8/365 26/17354 3.98062229814848e-08 1.81516376795571e-06 1.41626351239388e-06 CXCR3/CXCR6/CCRL2/CCR1/CCR7/CCR5/CMKLR1/CXCR4 8 MF GO:0004950 chemokine receptor activity 8/365 26/17354 3.98062229814848e-08 1.81516376795571e-06 1.41626351239388e-06 CXCR3/CXCR6/CCRL2/CCR1/CCR7/CCR5/CMKLR1/CXCR4 8 MF GO:0042605 peptide antigen binding 8/365 26/17354 3.98062229814848e-08 1.81516376795571e-06 1.41626351239388e-06 HLA-DRB1/HLA-DQB1/HLA-DPA1/HLA-DRA/HLA-E/HLA-DQA1/HLA-DPB1/HLA-DRB5 8 MF GO:0023026 MHC class II protein complex binding 6/365 16/17354 5.56816327775619e-07 2.30825677696075e-05 1.8009944381642e-05 CD74/HLA-DRB1/HLA-DMA/HLA-DRA/HLA-DMB/HLA-DOA 6 MF GO:0030695 GTPase regulator activity 22/365 313/17354 8.56434387837251e-07 3.25445067378156e-05 2.53925283411396e-05 WAS/ACAP1/ADAP2/SMAP2/DOCK2/RGS1/RGS19/PREX1/ARHGAP45/ARHGAP25/AGAP2/ARHGEF6/TAGAP/GMIP/TBC1D10C/GPSM3/ARHGAP9/RASGRP1/ARHGDIB/RASAL3/NCKAP1L/ARHGAP30 22 MF GO:0005125 cytokine activity 18/365 220/17354 9.98696832511426e-07 3.3170019556206e-05 2.58805785087664e-05 CXCL9/FLT3LG/CCL4L1/EBI3/CCL3L1/CCL3L3/CXCL11/CSF1/CXCL10/CCL13/IL16/CCL3/XCL2/CCL5/IL15/CCL4/TNFSF13B/CCL18 18 MF GO:0004715 non-membrane spanning protein tyrosine kinase activity 9/365 51/17354 1.01837779339229e-06 3.3170019556206e-05 2.58805785087664e-05 SLA/ZAP70/FGR/HCK/BTK/PTK2B/LCK/JAK3/SLA2 9 MF GO:0023023 MHC protein complex binding 6/365 20/17354 2.5095837120568e-06 7.49957229033912e-05 5.85146683779922e-05 CD74/HLA-DRB1/HLA-DMA/HLA-DRA/HLA-DMB/HLA-DOA 6 MF GO:0005096 GTPase activator activity 20/365 284/17354 2.6314288738032e-06 7.49957229033912e-05 5.85146683779922e-05 ACAP1/ADAP2/SMAP2/DOCK2/RGS1/RGS19/PREX1/ARHGAP45/ARHGAP25/AGAP2/ARHGEF6/TAGAP/GMIP/TBC1D10C/ARHGAP9/RASGRP1/ARHGDIB/RASAL3/NCKAP1L/ARHGAP30 20 MF GO:0005126 cytokine receptor binding 19/365 268/17354 4.25042225495738e-06 0.000114011326368269 8.89562057074672e-05 CXCL9/CCL4L1/EBI3/CD300LF/CCL3L1/CCL3L3/CCRL2/CXCL11/CSF1/CXCL10/CCL13/CCL3/IL12RB1/XCL2/CCL5/IL15/CCL4/TNFSF13B/CCL18 19 MF GO:0060589 nucleoside-triphosphatase regulator activity 22/365 350/17354 5.3445464555742e-06 0.000135395176874546 0.000105640742806087 WAS/ACAP1/ADAP2/SMAP2/DOCK2/RGS1/RGS19/PREX1/ARHGAP45/ARHGAP25/AGAP2/ARHGEF6/TAGAP/GMIP/TBC1D10C/GPSM3/ARHGAP9/RASGRP1/ARHGDIB/RASAL3/NCKAP1L/ARHGAP30 22 MF GO:0001784 phosphotyrosine residue binding 7/365 35/17354 6.95763693386003e-06 0.000166983286412641 0.000130287051725468 FGR/PTPN6/VAV1/HCK/SAMSN1/LCK/PLCG2 7 MF GO:0019956 chemokine binding 6/365 24/17354 8.11564862567635e-06 0.000185036788665421 0.000144373117656769 CXCR3/CXCR6/CCR1/CCR7/CCR5/CXCR4 6 MF GO:0015026 coreceptor activity 7/365 40/17354 1.76224019671088e-05 0.000382657871285792 0.000298565005758536 CD8A/CXCR6/CD4/CCR5/LY96/CD86/CXCR4 7 MF GO:0001618 virus receptor activity 9/365 73/17354 2.16348454361826e-05 0.000428934326908665 0.000334671750912116 CLEC5A/SELPLG/ITGB7/MRC1/CD4/TNFRSF4/CCR5/CD86/CXCR4 9 MF GO:0104005 hijacked molecular function 9/365 73/17354 2.16348454361826e-05 0.000428934326908665 0.000334671750912116 CLEC5A/SELPLG/ITGB7/MRC1/CD4/TNFRSF4/CCR5/CD86/CXCR4 9 MF GO:0045309 protein phosphorylated amino acid binding 7/365 44/17354 3.36973858836407e-05 0.000640250331789173 0.000499548966169761 FGR/PTPN6/VAV1/HCK/SAMSN1/LCK/PLCG2 7 MF GO:0042288 MHC class I protein binding 5/365 19/17354 3.65205359960883e-05 0.000666134576568651 0.000519744891228541 PILRA/LILRB1/LILRB2/CD8A/HLA-E 5 MF GO:0042169 SH2 domain binding 6/365 32/17354 4.74012629185248e-05 0.00083134522657105 0.000648648860990339 SIT1/LILRB1/PTPN6/LAT2/PAG1/LCK 6 MF GO:0005085 guanyl-nucleotide exchange factor activity 19/365 320/17354 5.09987414473802e-05 0.000858996956470815 0.000670223848769934 DOCK10/FGD2/DOCK2/DOCK8/PREX1/NCF4/ARHGEF6/TAGAP/VAV1/DENND2D/IL2RB/DENND1C/FGD3/RASGRP1/ELMO1/JAK3/IL2RA/IL2RG/CYTH4 19 MF GO:0033218 amide binding 18/365 294/17354 5.40402506968127e-05 0.000858996956470815 0.000670223848769934 TLR2/CD74/PSAP/HLA-DRB1/LILRB2/CD300LF/HLA-DQB1/MSR1/HLA-DPA1/CD14/ITGB2/HLA-DRA/HLA-E/HLA-DQA1/APOE/HLA-DPB1/FOLR2/HLA-DRB5 18 MF GO:0004875 complement receptor activity 4/365 11/17354 5.65129576625536e-05 0.000858996956470815 0.000670223848769934 FPR3/C3AR1/FPR1/C5AR1 4 MF GO:0019864 IgG binding 4/365 11/17354 5.65129576625536e-05 0.000858996956470815 0.000670223848769934 FCGR3A/FCGR2A/FCGR2C/FCER1G 4 MF GO:0008528 G-protein coupled peptide receptor activity 11/365 130/17354 9.54709582684528e-05 0.00140434699904563 0.0010957278062729 FPR3/GPR84/CXCR3/CXCR6/CCRL2/CCR1/CCR7/FPR1/CCR5/CMKLR1/CXCR4 11 MF GO:0019865 immunoglobulin binding 5/365 23/17354 9.86106028836491e-05 0.001405201091092 0.00109639420311426 FCGR3A/FCGR2A/FCGR2C/CD4/FCER1G 5 MF GO:0001653 peptide receptor activity 11/365 131/17354 0.00010229668245611 0.00141355415757533 0.00110291160032425 FPR3/GPR84/CXCR3/CXCR6/CCRL2/CCR1/CCR7/FPR1/CCR5/CMKLR1/CXCR4 11 MF GO:0003779 actin binding 21/365 403/17354 0.000134480326386193 0.00180361849506189 0.00140725542781837 WAS/COTL1/WIPF1/GBP1/MYO7A/GCSAM/GMFG/MYO1F/AIF1/FMNL1/LCP1/PARVG/EVL/MYO1G/CORO1A/LSP1/CCR5/MICAL1/RCSD1/CORO7/CXCR4 21 MF GO:0004435 phosphatidylinositol phospholipase C activity 5/365 27/17354 0.000220782782991007 0.00287648425839712 0.00224434829025445 CCR1/CCL5/CCR5/PLCB2/PLCG2 5 MF GO:0001530 lipopolysaccharide binding 5/365 28/17354 0.000264179737386625 0.00334627667356391 0.00261089915896723 TLR2/CD14/TLR4/CD6/TREM2 5 MF GO:0008329 signaling pattern recognition receptor activity 4/365 17/17354 0.000368767083440621 0.00421882938760001 0.00329169975302124 TLR2/CD14/TLR4/LY96 4 MF GO:0038187 pattern recognition receptor activity 4/365 17/17354 0.000368767083440621 0.00421882938760001 0.00329169975302124 TLR2/CD14/TLR4/LY96 4 MF GO:0046625 sphingolipid binding 4/365 17/17354 0.000368767083440621 0.00421882938760001 0.00329169975302124 PSAP/CD300LF/SELL/CERKL 4 MF GO:0004629 phospholipase C activity 5/365 30/17354 0.000370072753298246 0.00421882938760001 0.00329169975302124 CCR1/CCL5/CCR5/PLCB2/PLCG2 5 MF GO:0005543 phospholipid binding 19/365 375/17354 0.000394829325613353 0.00439127249950461 0.00342624677939187 ADAP2/FGD2/BIN2/PSAP/PREX1/APOC1/CD300LF/NCF4/NCF1C/ARHGAP9/BTK/RASGRP1/MYO1G/CD300A/APOE/PLA2G7/SNX10/SNX20/TREM2 19 MF GO:0042277 peptide binding 15/365 260/17354 0.000422078535325603 0.00458256695496369 0.00357550237944997 TLR2/CD74/HLA-DRB1/LILRB2/HLA-DQB1/MSR1/HLA-DPA1/CD14/ITGB2/HLA-DRA/HLA-E/HLA-DQA1/APOE/HLA-DPB1/HLA-DRB5 15 MF GO:0001664 G-protein coupled receptor binding 15/365 262/17354 0.000457409928256243 0.00485067272755457 0.00378468924726096 CXCL9/CCL4L1/PSAP/ADA2/CCL3L1/CCL3L3/CCRL2/CXCL11/CXCL10/CCL13/CCL3/XCL2/CCL5/CCL4/CCL18 15 MF GO:0038024 cargo receptor activity 7/365 68/17354 0.00055363519901301 0.00573767388068029 0.00447676309249755 STAB1/CD163/MSR1/APOBR/FOLR2/CD5/CD6 7 MF GO:0030545 receptor regulator activity 22/365 485/17354 0.000640046087779549 0.0064858003561661 0.00506048134899386 IL18BP/TYMP/CXCL9/FLT3LG/CCL4L1/EBI3/ADA2/CCL3L1/CCL3L3/GMFG/CXCL11/CSF1/CXCL10/CCL13/IL16/CCL3/XCL2/CCL5/IL15/CCL4/TNFSF13B/CCL18 22 MF GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 5/365 34/17354 0.000674502738018571 0.0066863749681841 0.00521697769909101 APOBEC3C/ADA2/APOBEC3D/APOBEC3G/APOBEC3H 5 MF GO:0048018 receptor ligand activity 21/365 456/17354 0.000697208817295761 0.00676440895078441 0.00527786293943936 TYMP/CXCL9/FLT3LG/CCL4L1/EBI3/ADA2/CCL3L1/CCL3L3/GMFG/CXCL11/CSF1/CXCL10/CCL13/IL16/CCL3/XCL2/CCL5/IL15/CCL4/TNFSF13B/CCL18 21 MF GO:0003823 antigen binding 12/365 193/17354 0.00081606487427298 0.00775261630559331 0.00604890191895323 LAG3/HLA-DRB1/HLA-DQB1/HLA-DPA1/HLA-DRA/HLA-E/HLA-DQA1/IL7R/CD40/HLA-DPB1/LILRB4/HLA-DRB5 12 MF GO:0005522 profilin binding 3/365 10/17354 0.000992112358484513 0.00923271909120282 0.00720373742573073 WIPF1/FMNL1/EVL 3 MF GO:0051219 phosphoprotein binding 7/365 77/17354 0.00116906759371015 0.0106618964546365 0.00831883887734799 FGR/PTPN6/VAV1/HCK/SAMSN1/LCK/PLCG2 7 MF GO:0017124 SH3 domain binding 9/365 125/17354 0.00131136402391739 0.0117251371550261 0.00914842187996035 WAS/WIPF1/PTPN6/INPP5D/CD3E/EVL/ELMO1/MICAL1/SH2D2A 9 MF GO:0005031 tumor necrosis factor-activated receptor activity 4/365 24/17354 0.00146579818634806 0.0126113957165041 0.00983991632543486 TNFRSF1B/CD27/TNFRSF4/CD40 4 MF GO:0005035 death receptor activity 4/365 24/17354 0.00146579818634806 0.0126113957165041 0.00983991632543486 TNFRSF1B/CD27/TNFRSF4/CD40 4 MF GO:0030246 carbohydrate binding 14/365 267/17354 0.00162777469281849 0.0137456529615783 0.0107249092821179 FBXO6/CLEC5A/KLRB1/CD69/CLEC2D/SIGLEC1/CD72/MAN2B1/CLEC4A/MRC1/SIGLEC10/SELL/SLC2A5/HK3 14 MF GO:0016493 C-C chemokine receptor activity 3/365 12/17354 0.00176282785213957 0.0146154454650117 0.0114035562492474 CCR1/CCR7/CCR5 3 MF GO:0048365 Rac GTPase binding 6/365 64/17354 0.00223084541660772 0.0180232982162718 0.0140624995316248 WAS/DOCK2/PREX1/VAV1/FMNL1/ARHGDIB 6 MF GO:0005525 GTP binding 17/365 370/17354 0.00225291227703397 0.0180232982162718 0.0140624995316248 GBP5/RAC2/SEPT6/GBP2/SEPT1/GIMAP7/GIMAP8/GBP4/GBP1/AGAP2/RAB33A/GIMAP2/GIMAP6/GIMAP1/RAB27A/RHOG/GIMAP4 17 MF GO:0005088 Ras guanyl-nucleotide exchange factor activity 13/365 248/17354 0.00236460515168595 0.0185906887787723 0.0145052003860227 FGD2/DOCK2/PREX1/ARHGEF6/VAV1/DENND2D/IL2RB/DENND1C/FGD3/RASGRP1/JAK3/IL2RA/IL2RG 13 MF GO:0032550 purine ribonucleoside binding 17/365 374/17354 0.0025180848009811 0.0194618079533454 0.0151848824751402 GBP5/RAC2/SEPT6/GBP2/SEPT1/GIMAP7/GIMAP8/GBP4/GBP1/AGAP2/RAB33A/GIMAP2/GIMAP6/GIMAP1/RAB27A/RHOG/GIMAP4 17 MF GO:0001883 purine nucleoside binding 17/365 377/17354 0.0027336429285979 0.0207756862573441 0.0162100229801069 GBP5/RAC2/SEPT6/GBP2/SEPT1/GIMAP7/GIMAP8/GBP4/GBP1/AGAP2/RAB33A/GIMAP2/GIMAP6/GIMAP1/RAB27A/RHOG/GIMAP4 17 MF GO:0032549 ribonucleoside binding 17/365 378/17354 0.00280882519286156 0.0209971194745061 0.0163827940498224 GBP5/RAC2/SEPT6/GBP2/SEPT1/GIMAP7/GIMAP8/GBP4/GBP1/AGAP2/RAB33A/GIMAP2/GIMAP6/GIMAP1/RAB27A/RHOG/GIMAP4 17 MF GO:0043548 phosphatidylinositol 3-kinase binding 4/365 29/17354 0.00301642021453194 0.0221852841584929 0.0173098477506247 NLRC3/HCST/LCK/CORO1A 4 MF GO:0001882 nucleoside binding 17/365 385/17354 0.0033847733448807 0.0244993118296127 0.0191153448716738 GBP5/RAC2/SEPT6/GBP2/SEPT1/GIMAP7/GIMAP8/GBP4/GBP1/AGAP2/RAB33A/GIMAP2/GIMAP6/GIMAP1/RAB27A/RHOG/GIMAP4 17 MF GO:0030676 Rac guanyl-nucleotide exchange factor activity 3/365 15/17354 0.00347907851051353 0.0247884343874089 0.0193409298775259 DOCK2/PREX1/VAV1 3 MF GO:0032561 guanyl ribonucleotide binding 17/365 389/17354 0.00375563834748022 0.0263472474838613 0.0205571783230496 GBP5/RAC2/SEPT6/GBP2/SEPT1/GIMAP7/GIMAP8/GBP4/GBP1/AGAP2/RAB33A/GIMAP2/GIMAP6/GIMAP1/RAB27A/RHOG/GIMAP4 17 MF GO:0019001 guanyl nucleotide binding 17/365 390/17354 0.00385341854836077 0.026575638254107 0.0207353779544972 GBP5/RAC2/SEPT6/GBP2/SEPT1/GIMAP7/GIMAP8/GBP4/GBP1/AGAP2/RAB33A/GIMAP2/GIMAP6/GIMAP1/RAB27A/RHOG/GIMAP4 17 MF GO:0005044 scavenger receptor activity 5/365 50/17354 0.00390475386628327 0.026575638254107 0.0207353779544972 STAB1/CD163/MSR1/CD5/CD6 5 MF GO:0045236 CXCR chemokine receptor binding 3/365 16/17354 0.00421577370713183 0.0282704825066487 0.0220577633592966 CXCL9/CXCL11/CXCL10 3 MF GO:0016298 lipase activity 8/365 123/17354 0.00448952122622952 0.0296698794081255 0.0231496289010767 CCR1/LIPA/PLA2G7/CCL5/CCR5/PLCB2/AOAH/PLCG2 8 MF GO:0004713 protein tyrosine kinase activity 10/365 179/17354 0.00468597180436835 0.0305257591827424 0.0238174205996467 SLA/ZAP70/FGR/CSF1R/HCK/BTK/PTK2B/LCK/JAK3/SLA2 10 MF GO:0005089 Rho guanyl-nucleotide exchange factor activity 6/365 77/17354 0.00562158455905178 0.0361048247736283 0.0281704311483988 FGD2/DOCK2/PREX1/ARHGEF6/VAV1/FGD3 6 MF GO:0001540 amyloid-beta binding 5/365 56/17354 0.00635607318485471 0.0402551301707465 0.0314086657380248 CD74/LILRB2/MSR1/ITGB2/APOE 5 MF GO:0017048 Rho GTPase binding 9/365 161/17354 0.00710871890265348 0.0444051482138354 0.0346466761225216 WAS/FGD2/DOCK2/PREX1/ARHGEF6/VAV1/FMNL1/FGD3/ARHGDIB 9 MF GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 4/365 37/17354 0.0073535441940274 0.0453137317902229 0.0353555894392782 ADAP2/ARHGAP9/BTK/MYO1G 4