Supplementary Table S5 List of the proteins utilized for gene-enrichment analysis about plasma m/l EVs. ,
"We show the list which Log10(P-value) became lower than -20. Category: Classification of GO Terms, Term: GO term identifier, Description: Term name, Log10(P-value): -2 represents 0.01, the more negative the better, InTerm_InList: #Genes of Upload Hit List in this Term / #Genes of Genome in this Term, Symbols: List of Symbols of upload hits in this term.",
,
Category,GO Biological Processes
Term,GO:0045055
Description,regulated exocytosis
Log10(P-value),-73.2
InTerm_InList,128/789
Symbols,"A1BG,A2M,SERPINA3,ACTN4,ACTN1,AHSG,ALAD,ALB,ALDOA,ANXA3,ANXA5,APOA1,APOH,RHOA,RHOG,ATP2A2,AZU1,C3,CAMP,CAT,CD9,CD14,CD36,CD44,CD59,CHGA,CLU,CNN2,CRHBP,CTSD,CTSG,CYBA,CYBB,DEFA1,CYB5R3,EEF2,ELANE,SERPINB1,DMTN,STOM,F13A1,FCER1G,FGA,FGB,FGG,FLNA,FN1,GDI2,GNAI2,GSN,GSTP1,HBB,HCK,HP,HRG,HSPA6,HSPA8,ITGA2B,ITGAX,ITGB2,ITGB3,KNG1,KRT1,LAMP1,LGALS3BP,LTF,LYZ,MMP9,MPO,NFKB1,PNP,P2RX1,PECAM1,SERPINA1,PIGR,PKM,PLG,PLEK,PPBP,PPIA,PROS1,PSMA5,PSMD2,PTPN6,PTPRC,RAB6A,RAC1,RAC2,RAP1B,RNASE3,S100A8,SELENOP,SOD1,STK10,STXBP2,TF,THBS1,TLN1,TMSB4X,TTN,TTR,TUBA4A,VCL,VCP,VWF,TAGLN2,STX11,SNAP23,OTOF,WDR1,ACTR2,TUBB4B,CAP1,CCT2,TMED10,CORO1A,MMRN1,ENDOD1,COTL1,BRPF3,DBNL,BIN2,DOK3,TXNDC5,FERMT3,ATAD3B,TUBB,LY6G6F"
,
Category,Reactome Gene Sets
Term,R-HSA-109582
Description,Hemostasis 
Log10(P-value),-61.2
InTerm_InList,105/621
Symbols,"A1BG,A2M,SERPINA3,ACTB,ACTN4,ACTN1,AHSG,ALB,ALDOA,ANXA5,APOA1,APOB,APOH,RHOA,RHOG,SERPINC1,ATP2A2,ATP2A3,ATP2B4,KIF1A,BSG,CAPZA1,CD9,CD36,CD44,CDC42,CENPE,CFL1,CLU,COL1A1,CSK,F13A1,FCER1G,FGA,FGB,FGG,FLNA,FN1,GNAI2,GNAQ,GNB1,GNB2,GP1BA,GP1BB,GP9,GRB2,GYPA,GYPC,HBB,HBD,HRG,HSPA5,JCHAIN,ITGA6,ITGA2B,ITGAX,ITGB1,ITGB2,ITGB3,ITPK1,KNG1,LGALS3BP,P2RX1,PECAM1,PFN1,SERPINA1,PLG,PLEK,PPBP,PPIA,PROS1,PTPN6,RAC1,RAC2,RAP1B,SELENOP,SLC3A2,SOD1,SPN,SRC,STXBP2,TF,THBS1,TLN1,TMSB4X,TTN,TUBA4A,VCL,VWF,YWHAZ,TAGLN2,PDE5A,DOK2,WDR1,TUBA1B,TUBB4B,CAP1,EHD1,AKAP10,MMRN1,ENDOD1,BRPF3,TUBB1,FERMT3,LY6G6F"
,
Category,GO Biological Processes
Term,GO:0006897
Description,endocytosis
Log10(P-value),-32.9
InTerm_InList,84/788
Symbols,"ACTB,ACTN4,GRK2,AHSG,ALB,ANK2,ANXA3,APOA1,APOB,APOC1,APOC2,APOC3,APOE,AZU1,ADGRB1,BICD1,C3,C4A,C4BPA,CALR,CD5L,CD9,CD14,CD36,CD151,CDC42,CLU,CLTC,CSK,CYBA,ELANE,FCER1G,FCGR3A,FCN2,GRB2,GSN,HBA1,HBB,HCK,HP,HPR,HPX,JCHAIN,ITGB1,ITGB2,ITGB3,LBP,LGALS3BP,LRP4,MFGE8,MYH9,OPHN1,PECAM1,MASP1,PTPRC,RAC1,SORL1,SRC,TF,THBS1,HSP90B1,EZR,VTN,APOL1,FCN3,PDLIM7,ACTR3,ACTR2,FLOT1,PRG4,CAP1,EHD1,LMAN2,CORO1A,CORO1C,DBNL,BIN2,ANKFY1,STAB2,MYO1G,COLEC11,TXNDC5,CD163L1,IGLL5"
,
Category,KEGG Pathway
Term,hsa04610
Description,Complement and coagulation cascades
Log10(P-value),-28.7
InTerm_InList,30/79
Symbols,"A2M,SERPINC1,CFB,C1QA,C1QB,C1QC,C1R,C1S,C3,C4A,C4BPA,C8B,C9,CD59,CLU,F13A1,FGA,FGB,FGG,CFH,ITGAX,ITGB2,KNG1,SERPINA1,PLG,PROS1,MASP1,VTN,VWF,MASP2"
,
Category,GO Biological Processes
Term,GO:0002253
Description,activation of immune response
Log10(P-value),-25.3
InTerm_InList,67/648
Symbols,"A2M,ACTB,APOB,CFB,C1QA,C1QB,C1QC,C1R,C1S,C3,C4A,C4BPA,C8B,C9,CD14,CD36,CD59,CDC42,CLU,CPN2,CSK,CYBA,EP300,FCER1G,FCGR3A,FCN2,FGA,FGB,FGG,FLOT2,GRB2,HCK,CFH,CFHR1,HLA-DRB1,HSPD1,IFI16,IRF3,ITGB2,KRT1,LBP,LTF,NFKB1,PROS1,MASP1,PTPN6,PTPRC,RAC1,S100A8,SEC14L1,SRC,HSP90B1,UBA52,EZR,VTN,FCN3,ACTR3,ACTR2,FLOT1,MASP2,RC3H2,NLRC4,MYO1G,COLEC11,MUC16,PGLYRP2,IGLL5"
,
Category,GO Biological Processes
Term,GO:0030036
Description,actin cytoskeleton organization
Log10(P-value),-24.8
InTerm_InList,66/642
Symbols,"ACTB,ACTN4,ACTN1,ADD1,ALDOA,APOA1,RHOA,RHOG,ARHGDIA,ARHGDIB,CALR,CAPZA1,CDC42,CFL1,CNN2,DBN1,EPB41,DMTN,FLNA,GMFB,GRB2,GSN,HCK,HRG,ICAM1,ILK,ITGB1,LCP1,MYBPC3,MYH9,OPHN1,PFN1,PLEK,RAC1,RAC2,RALA,RAN,RDX,SPTA1,SPTB,SRC,TLN1,TMSB4X,TPM1,TPM3,TPM4,HSP90B1,TSC1,TTN,VASP,EZR,ZYX,ALMS1,TMSB10,PDLIM7,SLC9A3R1,WDR1,ACTR3,ACTR2,CAP1,CORO1A,CLASP2,CORO1C,TMOD3,SPTBN5,MTPN"
,
Category,GO Biological Processes
Term,GO:0031589
Description,cell-substrate adhesion
Log10(P-value),-21.3
InTerm_InList,45/340
Symbols,"ACTN4,ACTN1,APOA1,APOD,RHOA,CALR,CD36,CD44,CDC42,COL1A1,DMTN,FAT2,FGA,FGB,FGG,FLNA,FN1,HRG,ILK,ITGA6,ITGA2B,ITGB1,ITGB2,ITGB3,LGALS1,LIMS1,PECAM1,VIT,PLG,RAC1,RAC2,SRC,THBS1,TSC1,VCL,VTN,VWF,ZYX,CORO1A,MMRN1,CLASP2,MACF1,CORO1C,MYO1G,FERMT3"
,
Category,Reactome Gene Sets
Term,R-HSA-5653656
Description,Vesicle-mediated transport
Log10(P-value),-21
InTerm_InList,62/667
Symbols,"ACTB,GRK2,AP1B1,ALB,ANK1,ANK2,APOA1,APOB,APOE,KIF1A,BICD1,CALR,CAPZA1,CD36,CD59,CENPE,CLTC,COL1A1,GDI2,GRB2,HBA1,HBB,HP,HPR,HPX,HSPA8,JCHAIN,MYH9,SERPINA1,MASP1,RAB6A,RAC1,RALA,SPTA1,SPTB,SRC,TF,HSP90B1,TSC1,TUBA4A,UBA52,YWHAB,YWHAE,YWHAH,YWHAZ,APOL1,RAB11A,SNAP23,USP6NL,ACTR3,ACTR2,TUBA1B,TUBB4B,LMAN2,YWHAQ,TMED10,RAB35,SPTBN5,STAB2,COLEC11,TUBB1,TXNDC5"
,
Category,GO Biological Processes
Term,GO:0043062
Description,extracellular structure organization
Log10(P-value),-20.6
InTerm_InList,48/405
Symbols,"A2M,AGT,ALB,APOA1,APOA4,APOB,APOC1,APOC2,APOC3,APOE,BSG,CD36,CD44,COL1A1,COL6A1,COL9A3,COL12A1,COL19A1,CTSG,ELANE,FGA,FGB,FGG,FN1,GSN,ICAM1,ITGA6,ITGA2B,ITGAX,ITGB1,ITGB2,ITGB3,LCP1,LPA,MMP9,MPO,P4HB,PECAM1,VIT,PLG,PON1,THBS1,TTR,VTN,VWF,FLOT1,CLASP2,COL24A1"
,
Category,GO Biological Processes
Term,GO:0060627
Description,regulation of vesicle-mediated transport
Log10(P-value),-20.3
InTerm_InList,53/505
Symbols,"ACTN4,AHSG,APOC1,APOC2,APOC3,APOE,ARHGAP1,ATP2A2,AZU1,BICD1,C3,C4A,C4BPA,CALR,CD14,CD36,CD151,CLU,CSK,CYBA,FCER1G,FGA,FGB,FGG,GNAI2,HCK,ITGB2,ITGB3,LAMP1,MFGE8,MSN,OPHN1,P2RX1,PTPRC,RAC1,RAC2,RALA,RAP1B,RDX,SORL1,SRC,STXBP2,TF,EZR,VTN,RAB11A,FLOT1,EHD1,LMAN2,CORO1A,CLASP2,ANKFY1,SMPD3"