Pathway identifier,Pathway name,Pvalue,Gene list,Count
R-HSA-69190,DNA strand elongation,1.11E-16,ENSG00000163918;ENSG00000133119;ENSG00000132646;ENSG00000112118;ENSG00000198056;ENSG00000077514;ENSG00000073111;ENSG00000049541;ENSG00000076003;ENSG00000131153;ENSG00000111445;ENSG00000104738;ENSG00000062822;ENSG00000168496;ENSG00000166508;ENSG00000100297;ENSG00000105486;ENSG00000014138,18
R-HSA-453279,Mitotic G1 phase and G1/S transition,1.11E-16,ENSG00000132646;ENSG00000112118;ENSG00000198056;ENSG00000073111;ENSG00000123080;ENSG00000176890;ENSG00000131747;ENSG00000076003;ENSG00000134057;ENSG00000104738;ENSG00000135446;ENSG00000115233;ENSG00000145604;ENSG00000171848;ENSG00000101412;ENSG00000166508;ENSG00000167900;ENSG00000100297;ENSG00000101057;ENSG00000123374;ENSG00000162521;ENSG00000167513;ENSG00000014138,31
R-HSA-69278,"Cell Cycle, Mitotic",1.11E-16,ENSG00000163918;ENSG00000175063;ENSG00000072864;ENSG00000077514;ENSG00000073111;ENSG00000135446;ENSG00000115233;ENSG00000100749;ENSG00000062822;ENSG00000151725;ENSG00000168496;ENSG00000141577;ENSG00000147874;ENSG00000164611;ENSG00000058804;ENSG00000133119;ENSG00000136824;ENSG00000125450;ENSG00000112118;ENSG00000198056;ENSG00000154473;ENSG00000113569;ENSG00000075188;ENSG00000104738;ENSG00000113368;ENSG00000111581;ENSG00000145604;ENSG00000088325;ENSG00000132182;ENSG00000142856;ENSG00000101224;ENSG00000100297;ENSG00000162521;ENSG00000123080;ENSG00000049541;ENSG00000176890;ENSG00000152240;ENSG00000131747;ENSG00000076003;ENSG00000134057;ENSG00000131462;ENSG00000249115;ENSG00000117399;ENSG00000122952;ENSG00000120539;ENSG00000164032;ENSG00000095319;ENSG00000101412;ENSG00000087586;ENSG00000167900;ENSG00000149636;ENSG00000101057;ENSG00000120253;ENSG00000132646;ENSG00000010292;ENSG00000175216;ENSG00000135476;ENSG00000111445;ENSG00000131153;ENSG00000171848;ENSG00000123416;ENSG00000031691;ENSG00000186298;ENSG00000166508;ENSG00000123374;ENSG00000167513;ENSG00000149503;ENSG00000014138;ENSG00000105486,78
R-HSA-1640170,Cell Cycle,1.11E-16,ENSG00000163918;ENSG00000175063;ENSG00000072864;ENSG00000077514;ENSG00000073111;ENSG00000113456;ENSG00000135446;ENSG00000115233;ENSG00000100749;ENSG00000062822;ENSG00000151725;ENSG00000159055;ENSG00000168496;ENSG00000108384;ENSG00000141577;ENSG00000147874;ENSG00000164611;ENSG00000058804;ENSG00000133119;ENSG00000136824;ENSG00000125450;ENSG00000112118;ENSG00000198056;ENSG00000154473;ENSG00000113569;ENSG00000175792;ENSG00000075188;ENSG00000171792;ENSG00000104738;ENSG00000113368;ENSG00000111581;ENSG00000145604;ENSG00000088325;ENSG00000132182;ENSG00000142856;ENSG00000101224;ENSG00000100297;ENSG00000162521;ENSG00000121211;ENSG00000123080;ENSG00000049541;ENSG00000176890;ENSG00000152240;ENSG00000131747;ENSG00000076003;ENSG00000134057;ENSG00000175643;ENSG00000203760;ENSG00000131462;ENSG00000249115;ENSG00000117399;ENSG00000163781;ENSG00000122952;ENSG00000120539;ENSG00000164032;ENSG00000095319;ENSG00000101412;ENSG00000087586;ENSG00000167900;ENSG00000149636;ENSG00000101057;ENSG00000120253;ENSG00000102054;ENSG00000132646;ENSG00000010292;ENSG00000175216;ENSG00000135476;ENSG00000137337;ENSG00000111445;ENSG00000131153;ENSG00000178966;ENSG00000171848;ENSG00000123416;ENSG00000031691;ENSG00000186298;ENSG00000166508;ENSG00000123374;ENSG00000167513;ENSG00000149503;ENSG00000014138;ENSG00000105486,90
R-HSA-73894,DNA Repair,1.11E-16,ENSG00000136518;ENSG00000163918;ENSG00000221829;ENSG00000095002;ENSG00000077514;ENSG00000129484;ENSG00000049541;ENSG00000162607;ENSG00000175643;ENSG00000075131;ENSG00000113456;ENSG00000152422;ENSG00000077152;ENSG00000205581;ENSG00000062822;ENSG00000163781;ENSG00000118655;ENSG00000182481;ENSG00000100823;ENSG00000116062;ENSG00000168496;ENSG00000164032;ENSG00000108384;ENSG00000133119;ENSG00000132646;ENSG00000111602;ENSG00000175792;ENSG00000042088;ENSG00000171792;ENSG00000137337;ENSG00000132781;ENSG00000111445;ENSG00000111247;ENSG00000178966;ENSG00000188612;ENSG00000123374;ENSG00000105486,38
R-HSA-69620,Cell Cycle Checkpoints,1.11E-16,ENSG00000163918;ENSG00000175063;ENSG00000072864;ENSG00000073111;ENSG00000049541;ENSG00000076003;ENSG00000134057;ENSG00000175643;ENSG00000113456;ENSG00000115233;ENSG00000117399;ENSG00000163781;ENSG00000122952;ENSG00000151725;ENSG00000149636;ENSG00000120253;ENSG00000133119;ENSG00000125450;ENSG00000112118;ENSG00000154473;ENSG00000075188;ENSG00000175216;ENSG00000171792;ENSG00000137337;ENSG00000111445;ENSG00000104738;ENSG00000111581;ENSG00000178966;ENSG00000031691;ENSG00000186298;ENSG00000142856;ENSG00000166508;ENSG00000100297;ENSG00000123374;ENSG00000149503,35
R-HSA-69242,S Phase,2.22E-16,ENSG00000163918;ENSG00000175063;ENSG00000077514;ENSG00000073111;ENSG00000049541;ENSG00000076003;ENSG00000135446;ENSG00000115233;ENSG00000062822;ENSG00000168496;ENSG00000101412;ENSG00000133119;ENSG00000132646;ENSG00000112118;ENSG00000198056;ENSG00000111445;ENSG00000104738;ENSG00000131153;ENSG00000145604;ENSG00000166508;ENSG00000101224;ENSG00000100297;ENSG00000123374;ENSG00000162521;ENSG00000167513;ENSG00000105486;ENSG00000014138,27
R-HSA-69206,G1/S Transition,3.33E-16,ENSG00000132646;ENSG00000112118;ENSG00000198056;ENSG00000073111;ENSG00000176890;ENSG00000076003;ENSG00000134057;ENSG00000104738;ENSG00000135446;ENSG00000115233;ENSG00000145604;ENSG00000171848;ENSG00000101412;ENSG00000166508;ENSG00000167900;ENSG00000100297;ENSG00000123374;ENSG00000167513;ENSG00000162521;ENSG00000014138,25
R-HSA-69306,DNA Replication,8.88E-16,ENSG00000163918;ENSG00000133119;ENSG00000175063;ENSG00000132646;ENSG00000112118;ENSG00000198056;ENSG00000077514;ENSG00000073111;ENSG00000049541;ENSG00000076003;ENSG00000131153;ENSG00000111445;ENSG00000104738;ENSG00000115233;ENSG00000062822;ENSG00000145604;ENSG00000168496;ENSG00000101412;ENSG00000166508;ENSG00000100297;ENSG00000123374;ENSG00000167513;ENSG00000105486;ENSG00000014138,24
R-HSA-69239,Synthesis of DNA,2.33E-15,ENSG00000163918;ENSG00000133119;ENSG00000175063;ENSG00000132646;ENSG00000112118;ENSG00000198056;ENSG00000077514;ENSG00000073111;ENSG00000049541;ENSG00000076003;ENSG00000131153;ENSG00000111445;ENSG00000104738;ENSG00000115233;ENSG00000062822;ENSG00000145604;ENSG00000168496;ENSG00000166508;ENSG00000100297;ENSG00000123374;ENSG00000167513;ENSG00000105486;ENSG00000014138,23
R-HSA-68886,M Phase,8.33E-15,ENSG00000175063;ENSG00000072864;ENSG00000152240;ENSG00000134057;ENSG00000131462;ENSG00000249115;ENSG00000115233;ENSG00000100749;ENSG00000117399;ENSG00000122952;ENSG00000151725;ENSG00000120539;ENSG00000164032;ENSG00000095319;ENSG00000141577;ENSG00000149636;ENSG00000164611;ENSG00000147874;ENSG00000120253;ENSG00000058804;ENSG00000136824;ENSG00000125450;ENSG00000154473;ENSG00000113569;ENSG00000075188;ENSG00000175216;ENSG00000135476;ENSG00000010292;ENSG00000113368;ENSG00000111581;ENSG00000123416;ENSG00000132182;ENSG00000031691;ENSG00000186298;ENSG00000142856;ENSG00000149503,36
R-HSA-73886,Chromosome Maintenance,3.18E-14,ENSG00000102054;ENSG00000163918;ENSG00000133119;ENSG00000132646;ENSG00000198056;ENSG00000077514;ENSG00000049541;ENSG00000175792;ENSG00000111445;ENSG00000203760;ENSG00000062822;ENSG00000151725;ENSG00000031691;ENSG00000159055;ENSG00000168496;ENSG00000164032;ENSG00000142856;ENSG00000162521;ENSG00000105486;ENSG00000014138,20
R-HSA-5693532,DNA Double-Strand Break Repair,3.45E-14,ENSG00000163918;ENSG00000133119;ENSG00000132646;ENSG00000077514;ENSG00000129484;ENSG00000049541;ENSG00000111602;ENSG00000042088;ENSG00000137337;ENSG00000171792;ENSG00000111445;ENSG00000111247;ENSG00000175643;ENSG00000075131;ENSG00000113456;ENSG00000152422;ENSG00000178966;ENSG00000062822;ENSG00000163781;ENSG00000182481;ENSG00000168496;ENSG00000188612;ENSG00000108384;ENSG00000123374,24
R-HSA-5693538,Homology Directed Repair,1.63E-13,ENSG00000163918;ENSG00000133119;ENSG00000132646;ENSG00000077514;ENSG00000129484;ENSG00000049541;ENSG00000111602;ENSG00000137337;ENSG00000171792;ENSG00000111445;ENSG00000111247;ENSG00000175643;ENSG00000075131;ENSG00000113456;ENSG00000178966;ENSG00000062822;ENSG00000163781;ENSG00000168496;ENSG00000188612;ENSG00000108384;ENSG00000123374,21
R-HSA-68877,Mitotic Prometaphase,4.54E-12,ENSG00000136824;ENSG00000125450;ENSG00000072864;ENSG00000154473;ENSG00000152240;ENSG00000075188;ENSG00000010292;ENSG00000175216;ENSG00000134057;ENSG00000111581;ENSG00000131462;ENSG00000249115;ENSG00000117399;ENSG00000122952;ENSG00000151725;ENSG00000123416;ENSG00000031691;ENSG00000186298;ENSG00000142856;ENSG00000141577;ENSG00000149636;ENSG00000147874;ENSG00000120253;ENSG00000149503,24
R-HSA-69186,Lagging Strand Synthesis,5.40E-12,ENSG00000062822;ENSG00000163918;ENSG00000133119;ENSG00000132646;ENSG00000077514;ENSG00000198056;ENSG00000049541;ENSG00000168496;ENSG00000111445;ENSG00000014138;ENSG00000105486,11
R-HSA-5693567,HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA),5.88E-12,ENSG00000163918;ENSG00000133119;ENSG00000132646;ENSG00000077514;ENSG00000049541;ENSG00000111602;ENSG00000137337;ENSG00000171792;ENSG00000111445;ENSG00000111247;ENSG00000175643;ENSG00000075131;ENSG00000113456;ENSG00000178966;ENSG00000062822;ENSG00000163781;ENSG00000188612;ENSG00000108384;ENSG00000123374,19
R-HSA-73933,Resolution of Abasic Sites (AP sites),1.53E-11,ENSG00000062822;ENSG00000163918;ENSG00000133119;ENSG00000132646;ENSG00000077514;ENSG00000129484;ENSG00000100823;ENSG00000049541;ENSG00000168496;ENSG00000132781;ENSG00000111445;ENSG00000105486,13
R-HSA-176187,Activation of ATR in response to replication stress,2.21E-11,ENSG00000163918;ENSG00000133119;ENSG00000112118;ENSG00000073111;ENSG00000049541;ENSG00000076003;ENSG00000166508;ENSG00000111445;ENSG00000104738;ENSG00000113456;ENSG00000100297;ENSG00000123374,12
R-HSA-4615885,SUMOylation of DNA replication proteins,2.52E-11,ENSG00000132646;ENSG00000125450;ENSG00000113569;ENSG00000131747;ENSG00000075188;ENSG00000111581;ENSG00000132182;ENSG00000095319;ENSG00000087586;ENSG00000188612;ENSG00000120253;ENSG00000149503;ENSG00000058804,13
R-HSA-5651801,PCNA-Dependent Long Patch Base Excision Repair,3.87E-11,ENSG00000062822;ENSG00000163918;ENSG00000133119;ENSG00000132646;ENSG00000077514;ENSG00000100823;ENSG00000049541;ENSG00000168496;ENSG00000111445;ENSG00000105486,10
R-HSA-69091,Polymerase switching,3.95E-11,ENSG00000062822;ENSG00000163918;ENSG00000133119;ENSG00000132646;ENSG00000077514;ENSG00000198056;ENSG00000049541;ENSG00000111445;ENSG00000014138,9
R-HSA-69109,Leading Strand Synthesis,3.95E-11,ENSG00000062822;ENSG00000163918;ENSG00000133119;ENSG00000132646;ENSG00000077514;ENSG00000198056;ENSG00000049541;ENSG00000111445;ENSG00000014138,9
R-HSA-110373,Resolution of AP sites via the multiple-nucleotide patch replacement pathway,4.79E-11,ENSG00000062822;ENSG00000163918;ENSG00000133119;ENSG00000132646;ENSG00000077514;ENSG00000129484;ENSG00000100823;ENSG00000049541;ENSG00000168496;ENSG00000111445;ENSG00000105486,11
R-HSA-69205,G1/S-Specific Transcription,6.68E-11,ENSG00000132646;ENSG00000171848;ENSG00000176890;ENSG00000101412;ENSG00000167900;ENSG00000162521;ENSG00000167513,12
R-HSA-174411,Polymerase switching on the C-strand of the telomere,6.70E-11,ENSG00000062822;ENSG00000163918;ENSG00000133119;ENSG00000132646;ENSG00000077514;ENSG00000198056;ENSG00000049541;ENSG00000111445;ENSG00000014138,9
R-HSA-180786,Extension of Telomeres,1.12E-10,ENSG00000062822;ENSG00000163918;ENSG00000133119;ENSG00000132646;ENSG00000077514;ENSG00000198056;ENSG00000049541;ENSG00000175792;ENSG00000168496;ENSG00000111445;ENSG00000014138;ENSG00000105486,12
R-HSA-68882,Mitotic Anaphase,1.42E-10,ENSG00000175063;ENSG00000125450;ENSG00000072864;ENSG00000154473;ENSG00000135476;ENSG00000075188;ENSG00000175216;ENSG00000113368;ENSG00000111581;ENSG00000115233;ENSG00000100749;ENSG00000117399;ENSG00000122952;ENSG00000151725;ENSG00000123416;ENSG00000031691;ENSG00000186298;ENSG00000142856;ENSG00000149636;ENSG00000164611;ENSG00000120253;ENSG00000149503,22
R-HSA-2555396,Mitotic Metaphase and Anaphase,1.85E-10,ENSG00000175063;ENSG00000125450;ENSG00000072864;ENSG00000154473;ENSG00000135476;ENSG00000075188;ENSG00000175216;ENSG00000113368;ENSG00000111581;ENSG00000115233;ENSG00000100749;ENSG00000117399;ENSG00000122952;ENSG00000151725;ENSG00000123416;ENSG00000031691;ENSG00000186298;ENSG00000142856;ENSG00000149636;ENSG00000164611;ENSG00000120253;ENSG00000149503,22
R-HSA-5685942,HDR through Homologous Recombination (HRR),1.85E-10,ENSG00000163918;ENSG00000133119;ENSG00000132646;ENSG00000077514;ENSG00000049541;ENSG00000171792;ENSG00000111445;ENSG00000111247;ENSG00000175643;ENSG00000113456;ENSG00000178966;ENSG00000062822;ENSG00000163781;ENSG00000108384,14
R-HSA-69481,G2/M Checkpoints,2.18E-10,ENSG00000163918;ENSG00000133119;ENSG00000112118;ENSG00000073111;ENSG00000049541;ENSG00000076003;ENSG00000137337;ENSG00000134057;ENSG00000171792;ENSG00000111445;ENSG00000175643;ENSG00000104738;ENSG00000113456;ENSG00000115233;ENSG00000178966;ENSG00000163781;ENSG00000166508;ENSG00000100297;ENSG00000123374,19
R-HSA-174417,Telomere C-strand (Lagging Strand) Synthesis,2.87E-10,ENSG00000062822;ENSG00000163918;ENSG00000133119;ENSG00000132646;ENSG00000077514;ENSG00000198056;ENSG00000049541;ENSG00000168496;ENSG00000111445;ENSG00000014138;ENSG00000105486,11
R-HSA-69618,Mitotic Spindle Checkpoint,5.96E-10,ENSG00000175063;ENSG00000125450;ENSG00000072864;ENSG00000154473;ENSG00000075188;ENSG00000175216;ENSG00000111581;ENSG00000117399;ENSG00000122952;ENSG00000151725;ENSG00000031691;ENSG00000186298;ENSG00000142856;ENSG00000149636;ENSG00000120253;ENSG00000149503,16
R-HSA-141424,Amplification of signal from the kinetochores,6.00E-10,ENSG00000125450;ENSG00000072864;ENSG00000154473;ENSG00000075188;ENSG00000175216;ENSG00000111581;ENSG00000117399;ENSG00000122952;ENSG00000151725;ENSG00000031691;ENSG00000186298;ENSG00000142856;ENSG00000149636;ENSG00000120253;ENSG00000149503,15
R-HSA-141444,Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal,6.00E-10,ENSG00000125450;ENSG00000072864;ENSG00000154473;ENSG00000075188;ENSG00000175216;ENSG00000111581;ENSG00000117399;ENSG00000122952;ENSG00000151725;ENSG00000031691;ENSG00000186298;ENSG00000142856;ENSG00000149636;ENSG00000120253;ENSG00000149503,15
R-HSA-5693579,Homologous DNA Pairing and Strand Exchange,1.30E-09,ENSG00000163781;ENSG00000163918;ENSG00000133119;ENSG00000049541;ENSG00000171792;ENSG00000111445;ENSG00000111247;ENSG00000175643;ENSG00000108384;ENSG00000113456;ENSG00000178966,11
R-HSA-2500257,Resolution of Sister Chromatid Cohesion,1.32E-09,ENSG00000125450;ENSG00000072864;ENSG00000154473;ENSG00000075188;ENSG00000175216;ENSG00000134057;ENSG00000111581;ENSG00000117399;ENSG00000122952;ENSG00000151725;ENSG00000123416;ENSG00000031691;ENSG00000186298;ENSG00000142856;ENSG00000149636;ENSG00000120253;ENSG00000149503,17
R-HSA-2467813,Separation of Sister Chromatids,1.54E-09,ENSG00000175063;ENSG00000125450;ENSG00000072864;ENSG00000154473;ENSG00000135476;ENSG00000075188;ENSG00000175216;ENSG00000111581;ENSG00000115233;ENSG00000117399;ENSG00000122952;ENSG00000151725;ENSG00000123416;ENSG00000031691;ENSG00000186298;ENSG00000142856;ENSG00000149636;ENSG00000164611;ENSG00000120253;ENSG00000149503,20
R-HSA-9648025,EML4 and NUDC in mitotic spindle formation,2.28E-09,ENSG00000125450;ENSG00000072864;ENSG00000154473;ENSG00000075188;ENSG00000175216;ENSG00000111581;ENSG00000117399;ENSG00000122952;ENSG00000151725;ENSG00000123416;ENSG00000031691;ENSG00000186298;ENSG00000142856;ENSG00000149636;ENSG00000120253;ENSG00000149503,16
R-HSA-68962,Activation of the pre-replicative complex,2.76E-09,ENSG00000112118;ENSG00000198056;ENSG00000073111;ENSG00000076003;ENSG00000166508;ENSG00000104738;ENSG00000100297;ENSG00000123374;ENSG00000167513;ENSG00000014138,10
R-HSA-5693607,Processing of DNA double-strand break ends,3.11E-09,ENSG00000163918;ENSG00000133119;ENSG00000049541;ENSG00000111602;ENSG00000137337;ENSG00000171792;ENSG00000111445;ENSG00000175643;ENSG00000075131;ENSG00000113456;ENSG00000178966;ENSG00000163781;ENSG00000188612;ENSG00000123374,14
R-HSA-1538133,G0 and Early G1,4.58E-09,ENSG00000132646;ENSG00000131747;ENSG00000101412;ENSG00000101057;ENSG00000123374;ENSG00000162521,10
R-HSA-176974,Unwinding of DNA,4.70E-09,ENSG00000112118;ENSG00000073111;ENSG00000076003;ENSG00000166508;ENSG00000131153;ENSG00000104738;ENSG00000100297,7
R-HSA-157579,Telomere Maintenance,5.12E-09,ENSG00000163918;ENSG00000133119;ENSG00000132646;ENSG00000198056;ENSG00000077514;ENSG00000049541;ENSG00000175792;ENSG00000111445;ENSG00000062822;ENSG00000168496;ENSG00000164032;ENSG00000105486;ENSG00000014138,13
R-HSA-5693616,Presynaptic phase of homologous DNA pairing and strand exchange,9.32E-09,ENSG00000163781;ENSG00000163918;ENSG00000133119;ENSG00000049541;ENSG00000171792;ENSG00000111445;ENSG00000175643;ENSG00000108384;ENSG00000113456;ENSG00000178966,10
R-HSA-73884,Base Excision Repair,1.02E-08,ENSG00000163918;ENSG00000133119;ENSG00000132646;ENSG00000077514;ENSG00000129484;ENSG00000049541;ENSG00000132781;ENSG00000111445;ENSG00000062822;ENSG00000100823;ENSG00000168496;ENSG00000164032;ENSG00000105486,14
R-HSA-159234,Transport of Mature mRNAs Derived from Intronless Transcripts,3.31E-08,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000111581;ENSG00000163950;ENSG00000120253;ENSG00000058804;ENSG00000119203,10
R-HSA-5663220,RHO GTPases Activate Formins,3.98E-08,ENSG00000125450;ENSG00000072864;ENSG00000154473;ENSG00000075188;ENSG00000175216;ENSG00000111581;ENSG00000117399;ENSG00000122952;ENSG00000151725;ENSG00000123416;ENSG00000031691;ENSG00000186298;ENSG00000142856;ENSG00000149636;ENSG00000120253;ENSG00000149503,16
R-HSA-2990846,SUMOylation,4.26E-08,ENSG00000132646;ENSG00000125450;ENSG00000113569;ENSG00000131747;ENSG00000075188;ENSG00000137337;ENSG00000152422;ENSG00000111581;ENSG00000055044;ENSG00000142230;ENSG00000132182;ENSG00000095319;ENSG00000087586;ENSG00000130816;ENSG00000188612;ENSG00000120253;ENSG00000149503;ENSG00000058804,18
R-HSA-6804756,Regulation of TP53 Activity through Phosphorylation,5.00E-08,ENSG00000163918;ENSG00000133119;ENSG00000049541;ENSG00000171792;ENSG00000111445;ENSG00000175643;ENSG00000113456;ENSG00000178966;ENSG00000163781;ENSG00000148835;ENSG00000088325;ENSG00000087586;ENSG00000123374,13
R-HSA-5696397,Gap-filling DNA repair synthesis and ligation in GG-NER,6.67E-08,ENSG00000062822;ENSG00000163918;ENSG00000133119;ENSG00000132646;ENSG00000077514;ENSG00000049541;ENSG00000111445;ENSG00000105486,8
R-HSA-2980766,Nuclear Envelope Breakdown,6.73E-08,ENSG00000100749;ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000134057;ENSG00000113368;ENSG00000111581;ENSG00000120253;ENSG00000058804,11
R-HSA-4570464,SUMOylation of RNA binding proteins,7.01E-08,ENSG00000055044;ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000188612;ENSG00000111581;ENSG00000120253;ENSG00000058804,10
R-HSA-5685938,HDR through Single Strand Annealing (SSA),8.22E-08,ENSG00000163781;ENSG00000163918;ENSG00000133119;ENSG00000049541;ENSG00000171792;ENSG00000111445;ENSG00000175643;ENSG00000113456;ENSG00000178966,9
R-HSA-4085377,SUMOylation of SUMOylation proteins,8.22E-08,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000188612;ENSG00000111581;ENSG00000120253;ENSG00000058804,9
R-HSA-159230,Transport of the SLBP Dependant Mature mRNA,1.02E-07,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000111581;ENSG00000163950;ENSG00000120253;ENSG00000058804,9
R-HSA-69183,Processive synthesis on the lagging strand,1.05E-07,ENSG00000062822;ENSG00000132646;ENSG00000077514;ENSG00000198056;ENSG00000168496;ENSG00000014138;ENSG00000105486,7
R-HSA-3108232,SUMO E3 ligases SUMOylate target proteins,1.16E-07,ENSG00000132646;ENSG00000125450;ENSG00000113569;ENSG00000131747;ENSG00000075188;ENSG00000137337;ENSG00000152422;ENSG00000111581;ENSG00000055044;ENSG00000132182;ENSG00000095319;ENSG00000087586;ENSG00000130816;ENSG00000188612;ENSG00000120253;ENSG00000149503;ENSG00000058804,17
R-HSA-180746,Nuclear import of Rev protein,1.25E-07,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000132341;ENSG00000111581;ENSG00000120253;ENSG00000058804,9
R-HSA-110314,Recognition of DNA damage by PCNA-containing replication complex,1.47E-07,ENSG00000062822;ENSG00000163918;ENSG00000133119;ENSG00000132646;ENSG00000077514;ENSG00000049541;ENSG00000162607;ENSG00000111445,8
R-HSA-3301854,Nuclear Pore Complex (NPC) Disassembly,1.53E-07,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000134057;ENSG00000111581;ENSG00000120253;ENSG00000058804,9
R-HSA-69002,DNA Replication Pre-Initiation,1.71E-07,ENSG00000112118;ENSG00000198056;ENSG00000073111;ENSG00000076003;ENSG00000101412;ENSG00000166508;ENSG00000104738;ENSG00000100297;ENSG00000123374;ENSG00000167513;ENSG00000115233;ENSG00000014138,12
R-HSA-453274,Mitotic G2-G2/M phases,2.08E-07,ENSG00000072864;ENSG00000152240;ENSG00000175216;ENSG00000134057;ENSG00000131462;ENSG00000249115;ENSG00000115233;ENSG00000123416;ENSG00000088325;ENSG00000101412;ENSG00000101224;ENSG00000087586;ENSG00000141577;ENSG00000123374;ENSG00000101057;ENSG00000147874;ENSG00000162521,18
R-HSA-165054,Rev-mediated nuclear export of HIV RNA,2.24E-07,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000132341;ENSG00000111581;ENSG00000120253;ENSG00000058804,9
R-HSA-5696399,Global Genome Nucleotide Excision Repair (GG-NER),2.72E-07,ENSG00000136518;ENSG00000062822;ENSG00000163918;ENSG00000133119;ENSG00000132646;ENSG00000077514;ENSG00000129484;ENSG00000049541;ENSG00000175792;ENSG00000111445;ENSG00000188612;ENSG00000105486,12
R-HSA-159231,Transport of Mature mRNA Derived from an Intronless Transcript,3.24E-07,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000111581;ENSG00000120253;ENSG00000058804;ENSG00000119203,9
R-HSA-177243,Interactions of Rev with host cellular proteins,3.24E-07,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000132341;ENSG00000111581;ENSG00000120253;ENSG00000058804,9
R-HSA-168276,NS1 Mediated Effects on Host Pathways,3.24E-07,ENSG00000125450;ENSG00000182481;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000111581;ENSG00000120253;ENSG00000058804,9
R-HSA-5633007,Regulation of TP53 Activity,4.22E-07,ENSG00000102054;ENSG00000163918;ENSG00000133119;ENSG00000049541;ENSG00000171792;ENSG00000111445;ENSG00000175643;ENSG00000113456;ENSG00000170633;ENSG00000178966;ENSG00000163781;ENSG00000148835;ENSG00000088325;ENSG00000087586;ENSG00000123374;ENSG00000162521,16
R-HSA-68875,Mitotic Prophase,4.28E-07,ENSG00000136824;ENSG00000125450;ENSG00000113569;ENSG00000075188;ENSG00000134057;ENSG00000113368;ENSG00000111581;ENSG00000100749;ENSG00000120539;ENSG00000132182;ENSG00000164032;ENSG00000095319;ENSG00000120253;ENSG00000058804,14
R-HSA-5619107,Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC),5.75E-07,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000111581;ENSG00000120253;ENSG00000058804,8
R-HSA-3108214,SUMOylation of DNA damage response and repair proteins,5.81E-07,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000137337;ENSG00000188612;ENSG00000152422;ENSG00000111581;ENSG00000120253;ENSG00000058804,11
R-HSA-69473,G2/M DNA damage checkpoint,5.81E-07,ENSG00000163781;ENSG00000163918;ENSG00000133119;ENSG00000049541;ENSG00000134057;ENSG00000137337;ENSG00000171792;ENSG00000111445;ENSG00000175643;ENSG00000113456;ENSG00000178966,11
R-HSA-5696398,Nucleotide Excision Repair,6.27E-07,ENSG00000136518;ENSG00000163918;ENSG00000133119;ENSG00000132646;ENSG00000077514;ENSG00000129484;ENSG00000049541;ENSG00000175792;ENSG00000111445;ENSG00000205581;ENSG00000062822;ENSG00000188612;ENSG00000105486,13
R-HSA-168253,Host Interactions with Influenza Factors,6.42E-07,ENSG00000125450;ENSG00000182481;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000111581;ENSG00000120253;ENSG00000058804,9
R-HSA-1362277,Transcription of E2F targets under negative control by DREAM complex,6.49E-07,ENSG00000132646;ENSG00000131747;ENSG00000101412;ENSG00000162521,7
R-HSA-194441,Metabolism of non-coding RNA,7.21E-07,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000111581;ENSG00000092208;ENSG00000120253;ENSG00000058804;ENSG00000064703,10
R-HSA-191859,snRNP Assembly,7.21E-07,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000111581;ENSG00000092208;ENSG00000120253;ENSG00000058804;ENSG00000064703,10
R-HSA-69275,G2/M Transition,8.67E-07,ENSG00000072864;ENSG00000152240;ENSG00000175216;ENSG00000134057;ENSG00000131462;ENSG00000249115;ENSG00000115233;ENSG00000123416;ENSG00000088325;ENSG00000101224;ENSG00000087586;ENSG00000141577;ENSG00000123374;ENSG00000101057;ENSG00000147874;ENSG00000162521,17
R-HSA-168333,NEP/NS2 Interacts with the Cellular Export Machinery,1.03E-06,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000132341;ENSG00000111581;ENSG00000120253;ENSG00000058804,9
R-HSA-159227,Transport of the SLBP independent Mature mRNA,1.04E-06,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000111581;ENSG00000120253;ENSG00000058804,8
R-HSA-606279,Deposition of new CENPA-containing nucleosomes at the centromere,1.20E-06,ENSG00000102054;ENSG00000151725;ENSG00000159055;ENSG00000175792;ENSG00000164032;ENSG00000031691;ENSG00000142856;ENSG00000203760;ENSG00000162521,9
R-HSA-774815,Nucleosome assembly,1.20E-06,ENSG00000102054;ENSG00000151725;ENSG00000159055;ENSG00000175792;ENSG00000164032;ENSG00000031691;ENSG00000142856;ENSG00000203760;ENSG00000162521,9
R-HSA-168274,Export of Viral Ribonucleoproteins from Nucleus,1.20E-06,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000132341;ENSG00000111581;ENSG00000120253;ENSG00000058804,9
R-HSA-170822,Regulation of Glucokinase by Glucokinase Regulatory Protein,1.25E-06,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000111581;ENSG00000120253;ENSG00000058804,8
R-HSA-5696400,Dual Incision in GG-NER,1.50E-06,ENSG00000062822;ENSG00000163918;ENSG00000133119;ENSG00000132646;ENSG00000077514;ENSG00000129484;ENSG00000049541;ENSG00000111445,8
R-HSA-69166,Removal of the Flap Intermediate,1.54E-06,ENSG00000062822;ENSG00000132646;ENSG00000198056;ENSG00000077514;ENSG00000168496;ENSG00000014138,6
R-HSA-72202,Transport of Mature Transcript to Cytoplasm,1.60E-06,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000111581;ENSG00000163950;ENSG00000141543;ENSG00000120253;ENSG00000058804;ENSG00000119203,11
R-HSA-68949,Orc1 removal from chromatin,1.76E-06,ENSG00000145604;ENSG00000112118;ENSG00000073111;ENSG00000076003;ENSG00000166508;ENSG00000104738;ENSG00000100297;ENSG00000123374;ENSG00000167513;ENSG00000115233,10
R-HSA-69052,Switching of origins to a post-replicative state,1.97E-06,ENSG00000175063;ENSG00000145604;ENSG00000112118;ENSG00000073111;ENSG00000076003;ENSG00000166508;ENSG00000104738;ENSG00000100297;ENSG00000123374;ENSG00000167513;ENSG00000115233,11
R-HSA-3232142,SUMOylation of ubiquitinylation proteins,2.13E-06,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000111581;ENSG00000120253;ENSG00000058804,8
R-HSA-3371453,Regulation of HSF1-mediated heat shock response,2.26E-06,ENSG00000105993;ENSG00000125450;ENSG00000105821;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000187522;ENSG00000111581;ENSG00000120253;ENSG00000058804,12
R-HSA-3371556,Cellular response to heat stress,2.48E-06,ENSG00000105993;ENSG00000110958;ENSG00000125450;ENSG00000105821;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000187522;ENSG00000111581;ENSG00000120253;ENSG00000058804,13
R-HSA-180910,Vpr-mediated nuclear import of PICs,2.52E-06,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000111581;ENSG00000120253;ENSG00000058804,8
R-HSA-8953750,Transcriptional Regulation by E2F6,3.48E-06,ENSG00000102054;ENSG00000171848;ENSG00000101412;ENSG00000122565;ENSG00000162521,8
R-HSA-4551638,SUMOylation of chromatin organization proteins,3.66E-06,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000188612;ENSG00000111581;ENSG00000120253;ENSG00000058804,9
R-HSA-176033,Interactions of Vpr with host cellular proteins,4.06E-06,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000111581;ENSG00000120253;ENSG00000058804,8
R-HSA-5578749,Transcriptional regulation by small RNAs,4.36E-06,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000164032;ENSG00000075188;ENSG00000095319;ENSG00000132341;ENSG00000111581;ENSG00000120253;ENSG00000058804,10
R-HSA-168271,Transport of Ribonucleoproteins into the Host Nucleus,4.73E-06,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000111581;ENSG00000120253;ENSG00000058804,8
R-HSA-5358565,Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha),4.82E-06,ENSG00000062822;ENSG00000132646;ENSG00000095002;ENSG00000077514;ENSG00000116062;ENSG00000105486,6
R-HSA-1169408,ISG15 antiviral mechanism,5.39E-06,ENSG00000125450;ENSG00000182481;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000111581;ENSG00000141543;ENSG00000120253;ENSG00000058804,10
R-HSA-5656169,Termination of translesion DNA synthesis,5.83E-06,ENSG00000062822;ENSG00000163918;ENSG00000133119;ENSG00000132646;ENSG00000077514;ENSG00000049541;ENSG00000111445,7
R-HSA-6782210,Gap-filling DNA repair synthesis and ligation in TC-NER,6.02E-06,ENSG00000062822;ENSG00000163918;ENSG00000133119;ENSG00000132646;ENSG00000077514;ENSG00000049541;ENSG00000111445;ENSG00000105486;ENSG00000205581,9
R-HSA-5358508,Mismatch Repair,6.19E-06,ENSG00000062822;ENSG00000132646;ENSG00000095002;ENSG00000077514;ENSG00000116062;ENSG00000105486,6
R-HSA-68867,Assembly of the pre-replicative complex,7.62E-06,ENSG00000112118;ENSG00000073111;ENSG00000076003;ENSG00000101412;ENSG00000166508;ENSG00000104738;ENSG00000100297;ENSG00000167513;ENSG00000115233,9
R-HSA-3700989,Transcriptional Regulation by TP53,7.68E-06,ENSG00000102054;ENSG00000163918;ENSG00000133119;ENSG00000132646;ENSG00000095002;ENSG00000049541;ENSG00000137337;ENSG00000134057;ENSG00000171792;ENSG00000111445;ENSG00000175643;ENSG00000113456;ENSG00000170633;ENSG00000178966;ENSG00000163781;ENSG00000148835;ENSG00000088325;ENSG00000101412;ENSG00000087586;ENSG00000123374;ENSG00000182973;ENSG00000162521,25
R-HSA-162587,HIV Life Cycle,9.42E-06,ENSG00000125450;ENSG00000196262;ENSG00000113569;ENSG00000075188;ENSG00000132341;ENSG00000152422;ENSG00000111581;ENSG00000148835;ENSG00000132182;ENSG00000168496;ENSG00000095319;ENSG00000120253;ENSG00000058804;ENSG00000105486,14
R-HSA-6784531,tRNA processing in the nucleus,9.57E-06,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000132341;ENSG00000111581;ENSG00000120253;ENSG00000058804,9
R-HSA-8854518,AURKA Activation by TPX2,1.48E-05,ENSG00000072864;ENSG00000152240;ENSG00000088325;ENSG00000175216;ENSG00000087586;ENSG00000141577;ENSG00000131462;ENSG00000249115;ENSG00000147874,9
R-HSA-1169410,Antiviral mechanism by IFN-stimulated genes,1.56E-05,ENSG00000125450;ENSG00000182481;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000111581;ENSG00000141543;ENSG00000120253;ENSG00000058804,10
R-HSA-73893,DNA Damage Bypass,1.62E-05,ENSG00000062822;ENSG00000163918;ENSG00000133119;ENSG00000132646;ENSG00000077514;ENSG00000049541;ENSG00000162607;ENSG00000111445,8
R-HSA-159236,Transport of Mature mRNA derived from an Intron-Containing Transcript,2.98E-05,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000111581;ENSG00000141543;ENSG00000120253;ENSG00000058804,9
R-HSA-8869496,TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation,2.99E-05,ENSG00000111641;ENSG00000101057,4
R-HSA-110312,Translesion synthesis by REV1,3.59E-05,ENSG00000133119;ENSG00000163918;ENSG00000132646;ENSG00000049541;ENSG00000111445,5
R-HSA-6781827,Transcription-Coupled Nucleotide Excision Repair (TC-NER),4.30E-05,ENSG00000062822;ENSG00000163918;ENSG00000133119;ENSG00000132646;ENSG00000077514;ENSG00000049541;ENSG00000111445;ENSG00000105486;ENSG00000205581,9
R-HSA-110313,Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template,4.32E-05,ENSG00000062822;ENSG00000163918;ENSG00000133119;ENSG00000132646;ENSG00000077514;ENSG00000049541;ENSG00000111445,7
R-HSA-174414,Processive synthesis on the C-strand of the telomere,4.57E-05,ENSG00000062822;ENSG00000132646;ENSG00000077514;ENSG00000168496;ENSG00000105486,5
R-HSA-5656121,Translesion synthesis by POLI,4.57E-05,ENSG00000133119;ENSG00000163918;ENSG00000132646;ENSG00000049541;ENSG00000111445,5
R-HSA-1362300,Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1,4.57E-05,ENSG00000101412;ENSG00000101057;ENSG00000162521,5
R-HSA-6782135,Dual incision in TC-NER,5.55E-05,ENSG00000062822;ENSG00000163918;ENSG00000133119;ENSG00000132646;ENSG00000077514;ENSG00000049541;ENSG00000111445;ENSG00000205581,8
R-HSA-5655862,Translesion synthesis by POLK,5.75E-05,ENSG00000133119;ENSG00000163918;ENSG00000132646;ENSG00000049541;ENSG00000111445,5
R-HSA-195258,RHO GTPase Effectors,6.20E-05,ENSG00000125450;ENSG00000072864;ENSG00000154473;ENSG00000075188;ENSG00000175216;ENSG00000111581;ENSG00000117399;ENSG00000122952;ENSG00000151725;ENSG00000123416;ENSG00000112290;ENSG00000031691;ENSG00000186298;ENSG00000164032;ENSG00000142856;ENSG00000149636;ENSG00000120253;ENSG00000149503,18
R-HSA-453276,Regulation of mitotic cell cycle,6.63E-05,ENSG00000117399;ENSG00000175063;ENSG00000145604;ENSG00000154473;ENSG00000134057;ENSG00000087586;ENSG00000123374;ENSG00000164611;ENSG00000115233,9
R-HSA-174143,APC/C-mediated degradation of cell cycle proteins,6.63E-05,ENSG00000117399;ENSG00000175063;ENSG00000145604;ENSG00000154473;ENSG00000134057;ENSG00000087586;ENSG00000123374;ENSG00000164611;ENSG00000115233,9
R-HSA-5358606,Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta),7.14E-05,ENSG00000062822;ENSG00000132646;ENSG00000095002;ENSG00000077514;ENSG00000105486,5
R-HSA-2565942,Regulation of PLK1 Activity at G2/M Transition,7.83E-05,ENSG00000072864;ENSG00000152240;ENSG00000175216;ENSG00000134057;ENSG00000087586;ENSG00000141577;ENSG00000131462;ENSG00000249115;ENSG00000147874,9
R-HSA-168325,Viral Messenger RNA Synthesis,8.23E-05,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000111581;ENSG00000120253;ENSG00000058804,8
R-HSA-211000,Gene Silencing by RNA,9.56E-05,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000164032;ENSG00000075188;ENSG00000095319;ENSG00000132341;ENSG00000111581;ENSG00000120253;ENSG00000058804,10
R-HSA-110320,Translesion Synthesis by POLH,1.07E-04,ENSG00000133119;ENSG00000163918;ENSG00000132646;ENSG00000049541;ENSG00000111445,5
R-HSA-390450,Folding of actin by CCT/TriC,1.23E-04,ENSG00000115484;ENSG00000150753;ENSG00000146731;ENSG00000166226,4
R-HSA-74160,Gene expression (Transcription),1.35E-04,ENSG00000163918;ENSG00000175063;ENSG00000113456;ENSG00000135446;ENSG00000115233;ENSG00000115750;ENSG00000119203;ENSG00000119403;ENSG00000058804;ENSG00000124795;ENSG00000133119;ENSG00000125450;ENSG00000113569;ENSG00000075188;ENSG00000171792;ENSG00000132341;ENSG00000111581;ENSG00000133398;ENSG00000145604;ENSG00000148835;ENSG00000088325;ENSG00000132182;ENSG00000162521;ENSG00000136518;ENSG00000095002;ENSG00000049541;ENSG00000134057;ENSG00000175643;ENSG00000170633;ENSG00000163781;ENSG00000164032;ENSG00000095319;ENSG00000101412;ENSG00000087586;ENSG00000101057;ENSG00000120253;ENSG00000102054;ENSG00000132646;ENSG00000111641;ENSG00000137337;ENSG00000111445;ENSG00000178966;ENSG00000138385;ENSG00000171848;ENSG00000130816;ENSG00000163950;ENSG00000122565;ENSG00000182973;ENSG00000123374;ENSG00000141543,57
R-HSA-72203,Processing of Capped Intron-Containing Pre-mRNA,1.35E-04,ENSG00000089280;ENSG00000125450;ENSG00000113569;ENSG00000165819;ENSG00000075188;ENSG00000170144;ENSG00000111581;ENSG00000153015;ENSG00000119203;ENSG00000132182;ENSG00000095319;ENSG00000163950;ENSG00000120253;ENSG00000141543;ENSG00000058804,15
R-HSA-162909,Host Interactions of HIV factors,1.64E-04,ENSG00000196262;ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000132341;ENSG00000111581;ENSG00000115233;ENSG00000120253;ENSG00000058804,11
R-HSA-162906,HIV Infection,1.72E-04,ENSG00000125450;ENSG00000196262;ENSG00000113569;ENSG00000075188;ENSG00000132341;ENSG00000152422;ENSG00000111581;ENSG00000115233;ENSG00000148835;ENSG00000132182;ENSG00000168496;ENSG00000095319;ENSG00000120253;ENSG00000058804;ENSG00000105486,15
R-HSA-5617833,Cilium Assembly,2.03E-04,ENSG00000180104;ENSG00000072864;ENSG00000152240;ENSG00000175216;ENSG00000150753;ENSG00000131462;ENSG00000249115;ENSG00000115484;ENSG00000081870;ENSG00000123416;ENSG00000141577;ENSG00000166226;ENSG00000147874,13
R-HSA-174437,Removal of the Flap Intermediate from the C-strand,2.11E-04,ENSG00000062822;ENSG00000132646;ENSG00000077514;ENSG00000168496,4
R-HSA-110362,POLB-Dependent Long Patch Base Excision Repair,2.11E-04,ENSG00000100823;ENSG00000129484;ENSG00000168496;ENSG00000105486,4
R-HSA-6791312,TP53 Regulates Transcription of Cell Cycle Genes,2.75E-04,ENSG00000132646;ENSG00000134057;ENSG00000101412;ENSG00000087586;ENSG00000182973;ENSG00000123374,7
R-HSA-389960,Formation of tubulin folding intermediates by CCT/TriC,2.98E-04,ENSG00000115484;ENSG00000123416;ENSG00000150753;ENSG00000146731;ENSG00000166226,5
R-HSA-162599,Late Phase of HIV Life Cycle,3.30E-04,ENSG00000148835;ENSG00000196262;ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000132341;ENSG00000111581;ENSG00000120253;ENSG00000058804,11
R-HSA-380284,Loss of proteins required for interphase microtubule organization from the centrosome,4.64E-04,ENSG00000072864;ENSG00000152240;ENSG00000175216;ENSG00000141577;ENSG00000131462;ENSG00000249115;ENSG00000147874,7
R-HSA-380259,Loss of Nlp from mitotic centrosomes,4.64E-04,ENSG00000072864;ENSG00000152240;ENSG00000175216;ENSG00000141577;ENSG00000131462;ENSG00000249115;ENSG00000147874,7
R-HSA-194315,Signaling by Rho GTPases,5.16E-04,ENSG00000125450;ENSG00000072864;ENSG00000154473;ENSG00000075188;ENSG00000175216;ENSG00000114346;ENSG00000111581;ENSG00000117399;ENSG00000122952;ENSG00000151725;ENSG00000123416;ENSG00000112290;ENSG00000031691;ENSG00000186298;ENSG00000164032;ENSG00000142856;ENSG00000161800;ENSG00000149636;ENSG00000120253;ENSG00000149503,20
R-HSA-380320,Recruitment of NuMA to mitotic centrosomes,5.97E-04,ENSG00000072864;ENSG00000152240;ENSG00000123416;ENSG00000175216;ENSG00000141577;ENSG00000131462;ENSG00000249115;ENSG00000147874,8
R-HSA-9605310,Defective Base Excision Repair Associated with MUTYH,6.95E-04,ENSG00000132781,2
R-HSA-9608290,Defective MUTYH substrate processing,6.95E-04,ENSG00000132781,2
R-HSA-5632968,Defective Mismatch Repair Associated With MSH6,6.95E-04,ENSG00000095002;ENSG00000116062,2
R-HSA-389958,Cooperation of Prefoldin and TriC/CCT  in actin and tubulin folding,7.64E-04,ENSG00000115484;ENSG00000123416;ENSG00000150753;ENSG00000146731;ENSG00000166226,5
R-HSA-72306,tRNA processing,8.11E-04,ENSG00000089195;ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000132341;ENSG00000144034;ENSG00000111581;ENSG00000120253;ENSG00000058804,11
R-HSA-113510,E2F mediated regulation of DNA replication,8.82E-04,ENSG00000198056;ENSG00000134057;ENSG00000101412;ENSG00000014138,4
R-HSA-9609690,HCMV Early Events,9.43E-04,ENSG00000102054;ENSG00000108468;ENSG00000125450;ENSG00000113569;ENSG00000123416;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000111581;ENSG00000162521;ENSG00000120253;ENSG00000058804,12
R-HSA-110357,Displacement of DNA glycosylase by APEX1,9.70E-04,ENSG00000100823;ENSG00000132781,3
R-HSA-380270,Recruitment of mitotic centrosome proteins and complexes,9.97E-04,ENSG00000072864;ENSG00000152240;ENSG00000175216;ENSG00000141577;ENSG00000131462;ENSG00000249115;ENSG00000147874,7
R-HSA-8953854,Metabolism of RNA,0.001004244,ENSG00000089280;ENSG00000165819;ENSG00000115233;ENSG00000153015;ENSG00000119203;ENSG00000064703;ENSG00000095319;ENSG00000092208;ENSG00000120253;ENSG00000058804;ENSG00000089195;ENSG00000150990;ENSG00000125450;ENSG00000113569;ENSG00000011260;ENSG00000111641;ENSG00000075188;ENSG00000132341;ENSG00000170144;ENSG00000111581;ENSG00000135698;ENSG00000055044;ENSG00000132182;ENSG00000144034;ENSG00000163950;ENSG00000182973;ENSG00000141543;ENSG00000108651,28
R-HSA-156711,Polo-like kinase mediated events,0.001038477,ENSG00000134057;ENSG00000101057;ENSG00000162521,4
R-HSA-380287,Centrosome maturation,0.001145616,ENSG00000072864;ENSG00000152240;ENSG00000175216;ENSG00000141577;ENSG00000131462;ENSG00000249115;ENSG00000147874,7
R-HSA-70171,Glycolysis,0.001325953,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000111581;ENSG00000120253;ENSG00000058804,8
R-HSA-162594,Early Phase of HIV Life Cycle,0.001407596,ENSG00000196262;ENSG00000168496;ENSG00000152422;ENSG00000105486,4
R-HSA-5632928,Defective Mismatch Repair Associated With MSH2,0.001545108,ENSG00000095002;ENSG00000116062,2
R-HSA-2262752,Cellular responses to stress,0.001595338,ENSG00000102054;ENSG00000105993;ENSG00000175063;ENSG00000110958;ENSG00000125450;ENSG00000105821;ENSG00000123080;ENSG00000113569;ENSG00000075188;ENSG00000113368;ENSG00000111581;ENSG00000135446;ENSG00000115233;ENSG00000123416;ENSG00000132182;ENSG00000164032;ENSG00000095319;ENSG00000101412;ENSG00000187522;ENSG00000168439;ENSG00000123374;ENSG00000120253;ENSG00000162521;ENSG00000058804,25
R-HSA-212300,PRC2 methylates histones and DNA,0.001633297,ENSG00000102054;ENSG00000119403;ENSG00000164032;ENSG00000130816;ENSG00000162521,5
R-HSA-69656,Cyclin A:Cdk2-associated events at S phase entry,0.001807788,ENSG00000145604;ENSG00000101412;ENSG00000101224;ENSG00000135446;ENSG00000123374;ENSG00000162521;ENSG00000115233,7
R-HSA-113501,Inhibition of replication initiation of damaged DNA by RB1/E2F1,0.002044358,ENSG00000198056;ENSG00000101412;ENSG00000014138,3
R-HSA-8953897,Cellular responses to external stimuli,0.002244649,ENSG00000102054;ENSG00000105993;ENSG00000175063;ENSG00000110958;ENSG00000125450;ENSG00000105821;ENSG00000123080;ENSG00000113569;ENSG00000075188;ENSG00000113368;ENSG00000111581;ENSG00000135446;ENSG00000115233;ENSG00000123416;ENSG00000132182;ENSG00000164032;ENSG00000095319;ENSG00000101412;ENSG00000187522;ENSG00000168439;ENSG00000123374;ENSG00000120253;ENSG00000162521;ENSG00000058804,25
R-HSA-389957,Prefoldin mediated transfer of substrate  to CCT/TriC,0.002403384,ENSG00000115484;ENSG00000150753;ENSG00000146731;ENSG00000166226,4
R-HSA-174178,APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1,0.002709897,ENSG00000117399;ENSG00000175063;ENSG00000145604;ENSG00000087586;ENSG00000164611;ENSG00000115233,6
R-HSA-5693554,Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA),0.002712405,ENSG00000175643;ENSG00000111247;ENSG00000108384;ENSG00000178966,4
R-HSA-2514853,Condensation of Prometaphase Chromosomes,0.003054697,ENSG00000136824;ENSG00000010292;ENSG00000134057,3
R-HSA-5620912,Anchoring of the basal body to the plasma membrane,0.0030568,ENSG00000072864;ENSG00000152240;ENSG00000175216;ENSG00000141577;ENSG00000131462;ENSG00000249115;ENSG00000147874,7
R-HSA-176409,APC/C:Cdc20 mediated degradation of mitotic proteins,0.003304762,ENSG00000117399;ENSG00000175063;ENSG00000154473;ENSG00000134057;ENSG00000164611;ENSG00000115233,6
R-HSA-8864260,Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors,0.003335354,ENSG00000111641;ENSG00000101057;ENSG00000124795,5
R-HSA-176814,Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins,0.003523146,ENSG00000117399;ENSG00000175063;ENSG00000154473;ENSG00000134057;ENSG00000164611;ENSG00000115233,6
R-HSA-5423599,Diseases of Mismatch Repair (MMR),0.004186489,ENSG00000095002;ENSG00000116062,2
R-HSA-5250913,Positive epigenetic regulation of rRNA expression,0.004505263,ENSG00000102054;ENSG00000164032;ENSG00000122565;ENSG00000162521;ENSG00000115750;ENSG00000124795,6
R-HSA-176408,Regulation of APC/C activators between G1/S and early anaphase,0.005065752,ENSG00000117399;ENSG00000175063;ENSG00000154473;ENSG00000134057;ENSG00000123374;ENSG00000115233,6
R-HSA-168254,Influenza Infection,0.005096766,ENSG00000125450;ENSG00000182481;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000132341;ENSG00000111581;ENSG00000120253;ENSG00000058804,10
R-HSA-5693568,Resolution of D-loop Structures through Holliday Junction Intermediates,0.005152244,ENSG00000175643;ENSG00000111247;ENSG00000108384;ENSG00000178966,4
R-HSA-912446,Meiotic recombination,0.005258831,ENSG00000164032;ENSG00000108384;ENSG00000123374;ENSG00000135446;ENSG00000121211,5
R-HSA-212165,Epigenetic regulation of gene expression,0.005428291,ENSG00000102054;ENSG00000119403;ENSG00000164032;ENSG00000130816;ENSG00000122565;ENSG00000162521;ENSG00000115750;ENSG00000124795,8
R-HSA-70326,Glucose metabolism,0.005658073,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000111581;ENSG00000120253;ENSG00000058804,8
R-HSA-5693537,Resolution of D-Loop Structures,0.005665792,ENSG00000175643;ENSG00000111247;ENSG00000108384;ENSG00000178966,4
R-HSA-9609646,HCMV Infection,0.005886241,ENSG00000102054;ENSG00000108468;ENSG00000125450;ENSG00000113569;ENSG00000123416;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000111581;ENSG00000162521;ENSG00000120253;ENSG00000058804,12
R-HSA-141405,Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components,0.006757746,ENSG00000117399;ENSG00000175063;ENSG00000154473,3
R-HSA-141430,Inactivation of APC/C via direct inhibition of the APC/C complex,0.006757746,ENSG00000117399;ENSG00000175063;ENSG00000154473,3
R-HSA-6804116,TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest,0.006757746,ENSG00000101412;ENSG00000123374,3
R-HSA-69202,Cyclin E associated events during G1/S transition ,0.0070544,ENSG00000145604;ENSG00000101412;ENSG00000123374;ENSG00000135446;ENSG00000162521;ENSG00000115233,6
R-HSA-390471,Association of TriC/CCT with target proteins during biosynthesis,0.007408338,ENSG00000115484;ENSG00000150753;ENSG00000146731;ENSG00000166226,4
R-HSA-6804114,TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest,0.007715968,ENSG00000132646;ENSG00000134057;ENSG00000087586,3
R-HSA-3065678,"SUMO is transferred from E1 to E2 (UBE2I, UBC9)",0.008004476,ENSG00000142230;ENSG00000188612,2
R-HSA-68911,G2 Phase,0.008004476,ENSG00000101412;ENSG00000123374,2
R-HSA-1500620,Meiosis,0.00866054,ENSG00000164032;ENSG00000108384;ENSG00000113368;ENSG00000123374;ENSG00000135446;ENSG00000121211,6
R-HSA-6783310,Fanconi Anemia Pathway,0.008746828,ENSG00000221829;ENSG00000118655;ENSG00000162607;ENSG00000077152,4
R-HSA-174048,APC/C:Cdc20 mediated degradation of Cyclin B,0.009862222,ENSG00000117399;ENSG00000175063;ENSG00000134057,3
R-HSA-3065676,SUMO is conjugated to E1 (UBA2:SAE1),0.010326254,ENSG00000142230;ENSG00000188612,2
R-HSA-176417,Phosphorylation of Emi1,0.010326254,ENSG00000117399;ENSG00000134057,2
R-HSA-8849470,PTK6 Regulates Cell Cycle,0.010326254,ENSG00000123374;ENSG00000135446,2
R-HSA-9605308,Diseases of Base Excision Repair,0.010326254,ENSG00000132781,2
R-HSA-168255,Influenza Life Cycle,0.010332013,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000132341;ENSG00000111581;ENSG00000120253;ENSG00000058804,9
R-HSA-6814122,Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding,0.011035559,ENSG00000115484;ENSG00000150753;ENSG00000146731;ENSG00000166226,4
R-HSA-5620922,BBSome-mediated cargo-targeting to cilium,0.011052564,ENSG00000115484;ENSG00000150753;ENSG00000166226,3
R-HSA-6790901,rRNA modification in the nucleus and cytosol,0.011888457,ENSG00000055044;ENSG00000150990;ENSG00000011260;ENSG00000111641;ENSG00000108651,5
R-HSA-9616222,Transcriptional regulation of granulopoiesis,0.011888457,ENSG00000164032;ENSG00000101412;ENSG00000123374;ENSG00000135446;ENSG00000124795,5
R-HSA-1852241,Organelle biogenesis and maintenance,0.012295883,ENSG00000180104;ENSG00000072864;ENSG00000152240;ENSG00000175216;ENSG00000150753;ENSG00000131462;ENSG00000249115;ENSG00000115484;ENSG00000081870;ENSG00000123416;ENSG00000141577;ENSG00000166226;ENSG00000147874,13
R-HSA-179409,APC-Cdc20 mediated degradation of Nek2A,0.012322341,ENSG00000117399;ENSG00000175063;ENSG00000154473,3
R-HSA-69231,Cyclin D associated events in G1,0.013678513,ENSG00000145604;ENSG00000123080;ENSG00000101412;ENSG00000135446,4
R-HSA-69236,G1 Phase,0.013678513,ENSG00000145604;ENSG00000123080;ENSG00000101412;ENSG00000135446,4
R-HSA-427389,ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression,0.013678513,ENSG00000102054;ENSG00000164032;ENSG00000122565;ENSG00000162521,4
R-HSA-2559583,Cellular Senescence,0.014460908,ENSG00000102054;ENSG00000175063;ENSG00000123080;ENSG00000164032;ENSG00000101412;ENSG00000113368;ENSG00000135446;ENSG00000123374;ENSG00000162521,9
R-HSA-72731,Recycling of eIF2:GDP,0.015741282,ENSG00000111361;ENSG00000115211,2
R-HSA-212436,Generic Transcription Pathway,0.018194144,ENSG00000136518;ENSG00000163918;ENSG00000175063;ENSG00000095002;ENSG00000049541;ENSG00000134057;ENSG00000175643;ENSG00000113456;ENSG00000135446;ENSG00000115233;ENSG00000170633;ENSG00000163781;ENSG00000164032;ENSG00000101412;ENSG00000087586;ENSG00000101057;ENSG00000124795;ENSG00000102054;ENSG00000133119;ENSG00000132646;ENSG00000111641;ENSG00000171792;ENSG00000137337;ENSG00000111445;ENSG00000133398;ENSG00000178966;ENSG00000145604;ENSG00000148835;ENSG00000171848;ENSG00000088325;ENSG00000182973;ENSG00000122565;ENSG00000123374;ENSG00000162521,41
R-HSA-73857,RNA Polymerase II Transcription,0.018412385,ENSG00000136518;ENSG00000163918;ENSG00000175063;ENSG00000095002;ENSG00000049541;ENSG00000134057;ENSG00000175643;ENSG00000113456;ENSG00000135446;ENSG00000115233;ENSG00000170633;ENSG00000119203;ENSG00000163781;ENSG00000164032;ENSG00000101412;ENSG00000087586;ENSG00000101057;ENSG00000124795;ENSG00000102054;ENSG00000133119;ENSG00000132646;ENSG00000111641;ENSG00000171792;ENSG00000137337;ENSG00000111445;ENSG00000133398;ENSG00000178966;ENSG00000145604;ENSG00000148835;ENSG00000171848;ENSG00000088325;ENSG00000163950;ENSG00000182973;ENSG00000122565;ENSG00000123374;ENSG00000162521;ENSG00000141543,44
R-HSA-9608287,Defective MUTYH substrate binding,0.018737864,ENSG00000132781,1
R-HSA-3214858,RMTs methylate histone arginines,0.018915339,ENSG00000136518;ENSG00000102054;ENSG00000164032;ENSG00000135446,4
R-HSA-168273,Influenza Viral RNA Transcription and Replication,0.019389802,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000111581;ENSG00000120253;ENSG00000058804,8
R-HSA-9610379,HCMV Late Events,0.019389802,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000111581;ENSG00000120253;ENSG00000058804,8
R-HSA-5620920,Cargo trafficking to the periciliary membrane,0.021313118,ENSG00000180104;ENSG00000115484;ENSG00000150753;ENSG00000166226,4
R-HSA-2465910,MASTL Facilitates Mitotic Progression,0.022116359,ENSG00000120539;ENSG00000134057,2
R-HSA-2559580,Oxidative Stress Induced Senescence,0.022382805,ENSG00000102054;ENSG00000123080;ENSG00000164032;ENSG00000101412;ENSG00000135446;ENSG00000162521,6
R-HSA-69273,Cyclin A/B1/B2 associated events during G2/M transition,0.023485246,ENSG00000134057;ENSG00000101224;ENSG00000123374,3
R-HSA-3215018,Processing and activation of SUMO,0.025639297,ENSG00000142230;ENSG00000188612,2
R-HSA-5619102,SLC transporter disorders,0.025846106,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000111581;ENSG00000120253;ENSG00000058804,8
R-HSA-73854,RNA Polymerase I Promoter Clearance,0.025864311,ENSG00000102054;ENSG00000164032;ENSG00000122565;ENSG00000162521;ENSG00000115750,5
R-HSA-73864,RNA Polymerase I Transcription,0.028128819,ENSG00000102054;ENSG00000164032;ENSG00000122565;ENSG00000162521;ENSG00000115750,5
R-HSA-2559582,Senescence-Associated Secretory Phenotype (SASP),0.029306758,ENSG00000175063;ENSG00000123080;ENSG00000164032;ENSG00000123374;ENSG00000135446,5
R-HSA-1474165,Reproduction,0.030792473,ENSG00000164032;ENSG00000108384;ENSG00000113368;ENSG00000123374;ENSG00000135446;ENSG00000121211,6
R-HSA-187577,SCF(Skp2)-mediated degradation of p27/p21,0.031124613,ENSG00000145604;ENSG00000123374;ENSG00000135446;ENSG00000115233,4
R-HSA-5685939,HDR through MMEJ (alt-NHEJ),0.033309187,ENSG00000129484;ENSG00000168496,2
R-HSA-162592,Integration of provirus,0.033309187,ENSG00000196262;ENSG00000152422,2
R-HSA-9632697,Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4,0.037125882,ENSG00000135446,1
R-HSA-5632927,Defective Mismatch Repair Associated With MSH3,0.037125882,ENSG00000095002,1
R-HSA-9630791,Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4,0.037125882,ENSG00000135446,1
R-HSA-68952,DNA replication initiation,0.037438235,ENSG00000198056;ENSG00000014138,2
R-HSA-2995410,Nuclear Envelope Reassembly,0.037438235,ENSG00000100749;ENSG00000113368,2
R-HSA-2995383,Initiation of Nuclear Envelope Reformation,0.037438235,ENSG00000100749;ENSG00000113368,2
R-HSA-110330,Recognition and association of DNA glycosylase with site containing an affected purine,0.038663767,ENSG00000164032;ENSG00000132781,3
R-HSA-174154,APC/C:Cdc20 mediated degradation of Securin,0.039517385,ENSG00000117399;ENSG00000175063;ENSG00000164611;ENSG00000115233,4
R-HSA-5696394,DNA Damage Recognition in GG-NER,0.041155127,ENSG00000136518;ENSG00000129484;ENSG00000175792,3
R-HSA-379724,tRNA Aminoacylation,0.041336041,ENSG00000162396;ENSG00000116120;ENSG00000106105;ENSG00000166986,4
R-HSA-174430,Telomere C-strand synthesis initiation,0.041751849,ENSG00000198056;ENSG00000014138,2
R-HSA-390466,Chaperonin-mediated protein folding,0.042804809,ENSG00000115484;ENSG00000123416;ENSG00000150753;ENSG00000146731;ENSG00000166226,5
R-HSA-2559585,Oncogene Induced Senescence,0.046374318,ENSG00000123080;ENSG00000101412;ENSG00000135446,3
R-HSA-174184,Cdc20:Phospho-APC/C mediated degradation of Cyclin A,0.049078013,ENSG00000117399;ENSG00000175063;ENSG00000154473;ENSG00000115233,4
R-HSA-176412,Phosphorylation of the APC/C,0.050899775,ENSG00000175063;ENSG00000134057,2
R-HSA-179419,APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint,0.051130041,ENSG00000117399;ENSG00000175063;ENSG00000154473;ENSG00000115233,4
R-HSA-8950505,Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation,0.051130041,ENSG00000196262;ENSG00000113368,4
R-HSA-391251,Protein folding,0.052437496,ENSG00000115484;ENSG00000123416;ENSG00000150753;ENSG00000146731;ENSG00000166226,5
R-HSA-110331,Cleavage of the damaged purine,0.054782534,ENSG00000164032;ENSG00000132781,3
R-HSA-9632693,Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects,0.055170563,ENSG00000135446,1
R-HSA-73930,Abasic sugar-phosphate removal via the single-nucleotide replacement pathway,0.055170563,ENSG00000100823,1
R-HSA-9630750,Evasion of Oncogene Induced Senescence Due to p16INK4A Defects,0.055170563,ENSG00000135446,1
R-HSA-4724289,Defective ALG6 causes ALG6-CDG (CDG-1c),0.055170563,ENSG00000088035,1
R-HSA-9630794,Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6,0.055170563,ENSG00000135446,1
R-HSA-9632700,Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6,0.055170563,ENSG00000135446,1
R-HSA-352238,Breakdown of the nuclear lamina,0.055170563,ENSG00000113368,1
R-HSA-73927,Depurination,0.057736283,ENSG00000164032;ENSG00000132781,3
R-HSA-176407,Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase,0.06068937,ENSG00000117399;ENSG00000175063,2
R-HSA-3214841,PKMTs methylate histone lysines,0.06703682,ENSG00000102054;ENSG00000152455;ENSG00000162521,3
R-HSA-73762,RNA Polymerase I Transcription Initiation,0.070279887,ENSG00000102054;ENSG00000162521;ENSG00000115750,3
R-HSA-379716,Cytosolic tRNA aminoacylation,0.070279887,ENSG00000116120;ENSG00000106105;ENSG00000166986,3
R-HSA-4419969,Depolymerisation of the Nuclear Lamina,0.071060761,ENSG00000134057;ENSG00000113368,2
R-HSA-8854521,Interaction between PHLDA1 and AURKA,0.072878294,ENSG00000087586,1
R-HSA-9649913,RAS GTPase cycle mutants,0.072878294,ENSG00000213281,1
R-HSA-9630747,Diseases of Cellular Senescence,0.072878294,ENSG00000135446,1
R-HSA-9020591,Interleukin-12 signaling,0.076722575,ENSG00000196262;ENSG00000113368,4
R-HSA-5619115,Disorders of transmembrane transporters,0.087114372,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000111581;ENSG00000115233;ENSG00000120253;ENSG00000058804,9
R-HSA-2299718,Condensation of Prophase Chromosomes,0.087515268,ENSG00000136824;ENSG00000164032;ENSG00000134057,3
R-HSA-6796648,TP53 Regulates Transcription of DNA Repair Genes,0.090124696,ENSG00000095002;ENSG00000137337,4
R-HSA-5693571,Nonhomologous End-Joining (NHEJ),0.094862607,ENSG00000042088;ENSG00000137337;ENSG00000152422,3
R-HSA-429947,Deadenylation of mRNA,0.099173079,ENSG00000182973;ENSG00000141543,2
R-HSA-75067,Processing of Capped Intronless Pre-mRNA,0.099173079,ENSG00000163950;ENSG00000119203,2
R-HSA-69200,Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes,0.107307869,ENSG00000123374,1
R-HSA-111448,Activation of NOXA and translocation to mitochondria,0.107307869,ENSG00000101412,1
R-HSA-3065679,SUMO is proteolytically processed,0.107307869,ENSG00000188612,1
R-HSA-447115,Interleukin-12 family signaling,0.110623593,ENSG00000196262;ENSG00000113368,4
R-HSA-8863678,Neurodegenerative Diseases,0.111158678,ENSG00000101224;ENSG00000113368,2
R-HSA-8862803,Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models,0.111158678,ENSG00000101224;ENSG00000113368,2
R-HSA-5250924,B-WICH complex positively regulates rRNA expression,0.114273573,ENSG00000164032;ENSG00000115750;ENSG00000124795,3
R-HSA-73929,"Base-Excision Repair, AP Site Formation",0.114273573,ENSG00000164032;ENSG00000132781,3
R-HSA-5689603,UCH proteinases,0.116832584,ENSG00000136518;ENSG00000175792;ENSG00000141568;ENSG00000115233,4
R-HSA-73772,RNA Polymerase I Promoter Escape,0.122426808,ENSG00000164032;ENSG00000122565;ENSG00000115750,3
R-HSA-69478,G2/M DNA replication checkpoint,0.124041903,ENSG00000134057,1
R-HSA-110381,Resolution of AP sites via the single-nucleotide replacement pathway,0.124041903,ENSG00000100823,1
R-HSA-5663205,Infectious disease,0.126963785,ENSG00000102054;ENSG00000108468;ENSG00000125450;ENSG00000196262;ENSG00000113569;ENSG00000075188;ENSG00000132341;ENSG00000152422;ENSG00000111581;ENSG00000115233;ENSG00000148835;ENSG00000182481;ENSG00000123416;ENSG00000132182;ENSG00000168496;ENSG00000095319;ENSG00000120253;ENSG00000162521;ENSG00000058804;ENSG00000105486,20
R-HSA-8866652,Synthesis of active ubiquitin: roles of E1 and E2 enzymes,0.129786656,ENSG00000175063;ENSG00000077152,2
R-HSA-73856,RNA Polymerase II Transcription Termination,0.13503903,ENSG00000163950;ENSG00000141543;ENSG00000119203,3
R-HSA-164525,Plus-strand DNA synthesis,0.140463376,ENSG00000196262,1
R-HSA-8937144,Aryl hydrocarbon receptor signalling,0.140463376,ENSG00000110958,1
R-HSA-3371497,HSP90 chaperone cycle for steroid hormone receptors (SHR),0.148076849,ENSG00000110958;ENSG00000123416;ENSG00000168439,3
R-HSA-5334118,DNA methylation,0.149069524,ENSG00000164032;ENSG00000130816,2
R-HSA-597592,Post-translational protein modification,0.149205713,ENSG00000136518;ENSG00000175063;ENSG00000130338;ENSG00000131747;ENSG00000152422;ENSG00000115233;ENSG00000077152;ENSG00000117399;ENSG00000159593;ENSG00000163964;ENSG00000095319;ENSG00000087586;ENSG00000084693;ENSG00000088035;ENSG00000165501;ENSG00000120253;ENSG00000058804;ENSG00000144401;ENSG00000102054;ENSG00000132646;ENSG00000125450;ENSG00000132768;ENSG00000113569;ENSG00000175792;ENSG00000075188;ENSG00000137337;ENSG00000111581;ENSG00000055044;ENSG00000145604;ENSG00000142230;ENSG00000123416;ENSG00000132182;ENSG00000130816;ENSG00000141568;ENSG00000188612;ENSG00000149503,36
R-HSA-2559586,DNA Damage/Telomere Stress Induced Senescence,0.15251089,ENSG00000164032;ENSG00000113368;ENSG00000123374,3
R-HSA-9006927,Signaling by Non-Receptor Tyrosine Kinases,0.15251089,ENSG00000213281;ENSG00000123374;ENSG00000135446,3
R-HSA-8848021,Signaling by PTK6,0.15251089,ENSG00000213281;ENSG00000123374;ENSG00000135446,3
R-HSA-162585,Uncoating of the HIV Virion,0.156578105,ENSG00000196262,1
R-HSA-6802953,RAS signaling downstream of NF1 loss-of-function variants,0.156578105,ENSG00000213281,1
R-HSA-113507,E2F-enabled inhibition of pre-replication complex formation,0.156578105,ENSG00000134057,1
R-HSA-2980767,"Activation of NIMA Kinases NEK9, NEK6, NEK7",0.156578105,ENSG00000134057,1
R-HSA-69017,CDK-mediated phosphorylation and removal of Cdc6,0.166057951,ENSG00000175063;ENSG00000123374;ENSG00000115233,3
R-HSA-6804758,Regulation of TP53 Activity through Acetylation,0.168879017,ENSG00000102054;ENSG00000162521,2
R-HSA-162589,Reverse Transcription of HIV RNA,0.172391798,ENSG00000196262,1
R-HSA-164516,Minus-strand DNA synthesis,0.172391798,ENSG00000196262,1
R-HSA-112412,SOS-mediated signalling,0.172391798,ENSG00000213281,1
R-HSA-139915,Activation of PUMA and translocation to mitochondria,0.172391798,ENSG00000101412,1
R-HSA-77588,SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs,0.187910058,ENSG00000163950,1
R-HSA-68689,CDC6 association with the ORC:origin complex,0.187910058,ENSG00000101412,1
R-HSA-1169092,Activation of RAS in B cells,0.187910058,ENSG00000213281,1
R-HSA-442729,CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde,0.187910058,ENSG00000182481,1
R-HSA-427413,NoRC negatively regulates rRNA expression,0.194131211,ENSG00000164032;ENSG00000130816;ENSG00000115750,3
R-HSA-204998,"Cell death signalling via NRAGE, NRIF and NADE",0.194131211,ENSG00000275700;ENSG00000142856;ENSG00000114346,3
R-HSA-3371511,HSF1 activation,0.195911656,ENSG00000105993;ENSG00000110958,2
R-HSA-6804757,Regulation of TP53 Degradation,0.195911656,ENSG00000123374;ENSG00000170633,2
R-HSA-499943,Interconversion of nucleotide di- and triphosphates,0.19892129,ENSG00000167325;ENSG00000171848;ENSG00000176890,3
R-HSA-8868773,rRNA processing in the nucleus and cytosol,0.200587024,ENSG00000055044;ENSG00000150990;ENSG00000011260;ENSG00000111641;ENSG00000135698;ENSG00000108651,6
R-HSA-9634635,Estrogen-stimulated signaling through PRKCZ,0.203138386,ENSG00000213281,1
R-HSA-171319,Telomere Extension By Telomerase,0.203138386,ENSG00000175792,1
R-HSA-1236394,Signaling by ERBB4,0.203739613,ENSG00000213281;ENSG00000117632,3
R-HSA-8852276,The role of GTSE1 in G2/M progression after G2 checkpoint,0.208584882,ENSG00000123416;ENSG00000134057;ENSG00000115233,3
R-HSA-427359,SIRT1 negatively regulates rRNA expression,0.209624226,ENSG00000164032;ENSG00000115750,2
R-HSA-913531,Interferon Signaling,0.211437332,ENSG00000125450;ENSG00000182481;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000111581;ENSG00000141543;ENSG00000120253;ENSG00000058804,10
R-HSA-8852135,Protein ubiquitination,0.213455809,ENSG00000132646;ENSG00000175063;ENSG00000077152,3
R-HSA-3247509,Chromatin modifying enzymes,0.213657574,ENSG00000136518;ENSG00000102054;ENSG00000175792;ENSG00000164032;ENSG00000152455;ENSG00000135446;ENSG00000162521,7
R-HSA-4839726,Chromatin organization,0.213657574,ENSG00000136518;ENSG00000102054;ENSG00000175792;ENSG00000164032;ENSG00000152455;ENSG00000135446;ENSG00000162521,7
R-HSA-6806003,Regulation of TP53 Expression and Degradation,0.216517184,ENSG00000123374;ENSG00000170633,2
R-HSA-173107,Binding and entry of HIV virion,0.218082178,ENSG00000196262,1
R-HSA-164843,2-LTR circle formation,0.218082178,ENSG00000152422,1
R-HSA-140342,Apoptosis induced DNA fragmentation,0.218082178,ENSG00000164104,1
R-HSA-2179392,EGFR Transactivation by Gastrin,0.218082178,ENSG00000213281,1
R-HSA-111932,CaMK IV-mediated phosphorylation of CREB,0.218082178,ENSG00000182481,1
R-HSA-5696395,Formation of Incision Complex in GG-NER,0.22343019,ENSG00000129484;ENSG00000188612,2
R-HSA-3371568,Attenuation phase,0.22343019,ENSG00000105993;ENSG00000110958,2
R-HSA-379726,Mitochondrial tRNA aminoacylation,0.22343019,ENSG00000162396;ENSG00000106105,2
R-HSA-1251985,Nuclear signaling by ERBB4,0.22343019,ENSG00000117632,2
R-HSA-2025928,Calcineurin activates NFAT,0.232746732,ENSG00000196262,1
R-HSA-9034864,Activated NTRK3 signals through RAS,0.232746732,ENSG00000213281,1
R-HSA-196819,Vitamin B1 (thiamin) metabolism,0.232746732,ENSG00000125454,1
R-HSA-73817,Purine ribonucleoside monophosphate biosynthesis,0.237303827,ENSG00000138363;ENSG00000163655,2
R-HSA-5250941,Negative epigenetic regulation of rRNA expression,0.238151141,ENSG00000164032;ENSG00000130816;ENSG00000115750,3
R-HSA-180689,APOBEC3G mediated resistance to HIV-1 infection,0.247137247,ENSG00000196262,1
R-HSA-9026519,Activated NTRK2 signals through RAS,0.247137247,ENSG00000213281,1
R-HSA-5358493,Synthesis of diphthamide-EEF2,0.247137247,ENSG00000132768,1
R-HSA-5693548,Sensing of DNA Double Strand Breaks,0.247137247,ENSG00000182481,1
R-HSA-75035,Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex,0.247137247,ENSG00000134057,1
R-HSA-8955332,Carboxyterminal post-translational modifications of tubulin,0.258189236,ENSG00000123416;ENSG00000084693,2
R-HSA-1168372,Downstream signaling events of B Cell Receptor (BCR),0.258242768,ENSG00000196262;ENSG00000213281;ENSG00000115233,3
R-HSA-4655427,SUMOylation of DNA methylation proteins,0.261258825,ENSG00000130816,1
R-HSA-179812,GRB2 events in EGFR signaling,0.261258825,ENSG00000213281,1
R-HSA-8851805,MET activates RAS signaling,0.261258825,ENSG00000213281,1
R-HSA-2428933,SHC-related events triggered by IGF1R,0.261258825,ENSG00000213281,1
R-HSA-9028731,Activated NTRK2 signals through FRS2 and FRS3,0.261258825,ENSG00000213281,1
R-HSA-75815,Ubiquitin-dependent degradation of Cyclin D,0.272130903,ENSG00000135446;ENSG00000115233,2
R-HSA-75153,Apoptotic execution phase,0.272130903,ENSG00000113368;ENSG00000164104,2
R-HSA-438064,Post NMDA receptor activation events,0.273457683,ENSG00000182481;ENSG00000123416;ENSG00000213281,3
R-HSA-72163,mRNA Splicing - Major Pathway,0.273802999,ENSG00000089280;ENSG00000170144;ENSG00000153015;ENSG00000141543;ENSG00000119203,5
R-HSA-2559584,Formation of Senescence-Associated Heterochromatin Foci (SAHF),0.275116475,ENSG00000113368,1
R-HSA-162658,Golgi Cisternae Pericentriolar Stack Reorganization,0.275116475,ENSG00000134057,1
R-HSA-8853334,Signaling by FGFR3 fusions in cancer,0.275116475,ENSG00000213281,1
R-HSA-174113,SCF-beta-TrCP mediated degradation of Emi1,0.279099537,ENSG00000117399;ENSG00000115233,2
R-HSA-8854050,FBXL7 down-regulates AURKA during mitotic entry and in early mitosis,0.279099537,ENSG00000087586;ENSG00000115233,2
R-HSA-5620924,Intraflagellar transport,0.286063535,ENSG00000081870;ENSG00000123416,2
R-HSA-6791226,Major pathway of rRNA processing in the nucleolus and cytosol,0.288235894,ENSG00000055044;ENSG00000150990;ENSG00000011260;ENSG00000135698;ENSG00000108651,5
R-HSA-205043,NRIF signals cell death from the nucleus,0.28871511,ENSG00000142856,1
R-HSA-9604323,Negative regulation of NOTCH4 signaling,0.293020632,ENSG00000013810;ENSG00000115233,2
R-HSA-72187,mRNA 3'-end processing,0.299968649,ENSG00000141543;ENSG00000119203,2
R-HSA-77595,Processing of Intronless Pre-mRNAs,0.302059556,ENSG00000119203,1
R-HSA-171007,p38MAPK events,0.302059556,ENSG00000213281,1
R-HSA-180336,SHC1 events in EGFR signaling,0.302059556,ENSG00000213281,1
R-HSA-399997,Acetylcholine regulates insulin secretion,0.302059556,ENSG00000277443,1
R-HSA-9027284,Erythropoietin activates RAS,0.302059556,ENSG00000213281,1
R-HSA-8876725,Protein methylation,0.302059556,ENSG00000144401,1
R-HSA-5655291,Signaling by FGFR4 in disease,0.302059556,ENSG00000213281,1
R-HSA-8878166,Transcriptional regulation by RUNX2,0.303475591,ENSG00000145604;ENSG00000134057;ENSG00000135446;ENSG00000115233,4
R-HSA-8951664,Neddylation,0.306450124,ENSG00000102054;ENSG00000145604;ENSG00000159593;ENSG00000130338;ENSG00000165501;ENSG00000115233,6
R-HSA-983231,Factors involved in megakaryocyte development and platelet production,0.306465805,ENSG00000123416;ENSG00000108384;ENSG00000161800;ENSG00000123374;ENSG00000149679,5
R-HSA-68827,CDT1 association with the CDC6:ORC:origin complex,0.306905489,ENSG00000167513;ENSG00000115233,2
R-HSA-3371571,HSF1-dependent transactivation,0.306905489,ENSG00000105993;ENSG00000110958,2
R-HSA-392499,Metabolism of proteins,0.308145742,ENSG00000136518;ENSG00000175063;ENSG00000106105;ENSG00000130338;ENSG00000131747;ENSG00000152422;ENSG00000115211;ENSG00000115233;ENSG00000077152;ENSG00000117399;ENSG00000162396;ENSG00000116120;ENSG00000159593;ENSG00000164032;ENSG00000163964;ENSG00000095319;ENSG00000087586;ENSG00000084693;ENSG00000088035;ENSG00000165501;ENSG00000120253;ENSG00000058804;ENSG00000144401;ENSG00000180104;ENSG00000102054;ENSG00000132646;ENSG00000125450;ENSG00000132768;ENSG00000113569;ENSG00000175792;ENSG00000075188;ENSG00000150753;ENSG00000137337;ENSG00000111361;ENSG00000111581;ENSG00000115484;ENSG00000055044;ENSG00000145604;ENSG00000142230;ENSG00000123416;ENSG00000132182;ENSG00000130816;ENSG00000141568;ENSG00000188612;ENSG00000166986;ENSG00000146731;ENSG00000166226;ENSG00000149503,48
R-HSA-72172,mRNA Splicing,0.313806557,ENSG00000089280;ENSG00000170144;ENSG00000153015;ENSG00000141543;ENSG00000119203,5
R-HSA-3232118,SUMOylation of transcription factors,0.315154545,ENSG00000188612,1
R-HSA-8849471,"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases",0.315154545,ENSG00000213281,1
R-HSA-72312,rRNA processing,0.319595784,ENSG00000055044;ENSG00000150990;ENSG00000011260;ENSG00000111641;ENSG00000135698;ENSG00000108651,6
R-HSA-1221632,Meiotic synapsis,0.327629192,ENSG00000164032;ENSG00000113368,2
R-HSA-8956320,Nucleobase biosynthesis,0.327629192,ENSG00000138363;ENSG00000163655,2
R-HSA-1963640,GRB2 events in ERBB2 signaling,0.328004725,ENSG00000213281,1
R-HSA-1250347,SHC1 events in ERBB4 signaling,0.328004725,ENSG00000213281,1
R-HSA-196791,Vitamin D (calciferol) metabolism,0.328004725,ENSG00000188612,1
R-HSA-9018519,Estrogen-dependent gene expression,0.333157169,ENSG00000110958;ENSG00000182481;ENSG00000164032,4
R-HSA-174084,Autodegradation of Cdh1 by Cdh1:APC/C,0.334501954,ENSG00000175063;ENSG00000115233,2
R-HSA-193648,NRAGE signals death through JNK,0.334501954,ENSG00000275700;ENSG00000114346,2
R-HSA-3214815,HDACs deacetylate histones,0.334501954,ENSG00000102054;ENSG00000162521,2
R-HSA-193704,p75 NTR receptor-mediated signalling,0.340089947,ENSG00000275700;ENSG00000142856;ENSG00000114346,3
R-HSA-190840,Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane,0.340614656,ENSG00000123416,1
R-HSA-3214847,HATs acetylate histones,0.345223431,ENSG00000136518;ENSG00000102054;ENSG00000175792,3
R-HSA-429914,Deadenylation-dependent mRNA decay,0.348184382,ENSG00000182973;ENSG00000141543,2
R-HSA-15869,Metabolism of nucleotides,0.349454044,ENSG00000138363;ENSG00000167325;ENSG00000171848;ENSG00000176890;ENSG00000167900;ENSG00000163655,6
R-HSA-73980,RNA Polymerase III Transcription Termination,0.352988814,ENSG00000138385,1
R-HSA-2564830,Cytosolic iron-sulfur cluster assembly,0.352988814,ENSG00000062822,1
R-HSA-190872,Transport of connexons to the plasma membrane,0.352988814,ENSG00000123416,1
R-HSA-210993,Tie2 Signaling,0.352988814,ENSG00000213281,1
R-HSA-442755,Activation of NMDA receptors and postsynaptic events,0.360599933,ENSG00000182481;ENSG00000123416;ENSG00000213281,3
R-HSA-201722,Formation of the beta-catenin:TCF transactivating complex,0.361772073,ENSG00000164032;ENSG00000175792,2
R-HSA-881907,Gastrin-CREB signalling pathway via PKC and MAPK,0.36513159,ENSG00000213281,1
R-HSA-983189,Kinesins,0.368526662,ENSG00000123416;ENSG00000161800,2
R-HSA-5617472,Activation of anterior HOX genes in hindbrain development during early embryogenesis,0.375923321,ENSG00000102054;ENSG00000164032;ENSG00000162521,3
R-HSA-5619507,Activation of HOX genes during differentiation,0.375923321,ENSG00000102054;ENSG00000164032;ENSG00000162521,3
R-HSA-389977,Post-chaperonin tubulin folding pathway,0.377047295,ENSG00000123416,1
R-HSA-5620916,VxPx cargo-targeting to cilium,0.377047295,ENSG00000180104,1
R-HSA-9634285,Constitutive Signaling by Overexpressed ERBB2,0.377047295,ENSG00000213281,1
R-HSA-8943724,Regulation of PTEN gene transcription,0.381950422,ENSG00000102054;ENSG00000162521,2
R-HSA-69580,p53-Dependent G1/S DNA damage checkpoint,0.381950422,ENSG00000123374;ENSG00000115233,2
R-HSA-69563,p53-Dependent G1 DNA Damage Response,0.381950422,ENSG00000123374;ENSG00000115233,2
R-HSA-6782315,tRNA modification in the nucleus and cytosol,0.381950422,ENSG00000089195;ENSG00000144034,2
R-HSA-5658442,Regulation of RAS by GAPs,0.388617012,ENSG00000213281;ENSG00000115233,2
R-HSA-167044,Signalling to RAS,0.388740162,ENSG00000213281,1
R-HSA-5654704,SHC-mediated cascade:FGFR3,0.388740162,ENSG00000213281,1
R-HSA-210991,Basigin interactions,0.388740162,ENSG00000196262,1
R-HSA-69615,G1/S DNA Damage Checkpoints,0.395251784,ENSG00000123374;ENSG00000115233,2
R-HSA-442982,Ras activation upon Ca2+ influx through NMDA receptor,0.400214341,ENSG00000213281,1
R-HSA-5654719,SHC-mediated cascade:FGFR4,0.400214341,ENSG00000213281,1
R-HSA-5654706,FRS-mediated FGFR3 signaling,0.400214341,ENSG00000213281,1
R-HSA-5637812,Signaling by EGFRvIII in Cancer,0.400214341,ENSG00000213281,1
R-HSA-5637810,Constitutive Signaling by EGFRvIII,0.400214341,ENSG00000213281,1
R-HSA-175474,Assembly Of The HIV Virion,0.400214341,ENSG00000196262,1
R-HSA-9034015,Signaling by NTRK3 (TRKC),0.400214341,ENSG00000213281,1
R-HSA-6802952,Signaling by BRAF and RAF fusions,0.401853589,ENSG00000177674;ENSG00000213281,2
R-HSA-5693606,DNA Double Strand Break Response,0.408421333,ENSG00000182481;ENSG00000137337,2
R-HSA-5654712,FRS-mediated FGFR4 signaling,0.411473909,ENSG00000213281,1
R-HSA-2173788,Downregulation of TGF-beta receptor signaling,0.411473909,ENSG00000186298,1
R-HSA-6804115,TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain,0.411473909,ENSG00000182973,1
R-HSA-9013507,NOTCH3 Activation and Transmission of Signal to the Nucleus,0.411473909,ENSG00000013810,1
R-HSA-5621575,CD209 (DC-SIGN) signaling,0.433365132,ENSG00000213281,1
R-HSA-5654688,SHC-mediated cascade:FGFR1,0.433365132,ENSG00000213281,1
R-HSA-264876,Insulin processing,0.433365132,ENSG00000180104,1
R-HSA-1445148,Translocation of SLC2A4 (GLUT4) to the plasma membrane,0.440714395,ENSG00000180104;ENSG00000123416,2
R-HSA-203927,MicroRNA (miRNA) biogenesis,0.444004566,ENSG00000132341,1
R-HSA-5654693,FRS-mediated FGFR1 signaling,0.444004566,ENSG00000213281,1
R-HSA-5218921,VEGFR2 mediated cell proliferation,0.444004566,ENSG00000213281,1
R-HSA-5689901,Metalloprotease DUBs,0.454444947,ENSG00000115233,1
R-HSA-5688426,Deubiquitination,0.462839609,ENSG00000136518;ENSG00000117399;ENSG00000145604;ENSG00000175792;ENSG00000141568;ENSG00000115233,6
R-HSA-73863,RNA Polymerase I Transcription Termination,0.464689984,ENSG00000115750,1
R-HSA-5654699,SHC-mediated cascade:FGFR2,0.464689984,ENSG00000213281,1
R-HSA-9006115,Signaling by NTRK2 (TRKB),0.464689984,ENSG00000213281,1
R-HSA-8939902,Regulation of RUNX2 expression and activity,0.46584233,ENSG00000145604;ENSG00000115233,2
R-HSA-171306,Packaging Of Telomere Ends,0.474743321,ENSG00000164032,1
R-HSA-73728,RNA Polymerase I Promoter Opening,0.474743321,ENSG00000164032,1
R-HSA-9619483,Activation of AMPK downstream of NMDARs,0.474743321,ENSG00000123416,1
R-HSA-5654700,FRS-mediated FGFR2 signaling,0.474743321,ENSG00000213281,1
R-HSA-73614,Pyrimidine salvage,0.474743321,ENSG00000167900,1
R-HSA-109581,Apoptosis,0.480254889,ENSG00000101412;ENSG00000113368;ENSG00000164104;ENSG00000115233,4
R-HSA-5654708,Downstream signaling of activated FGFR3,0.48460853,ENSG00000213281,1
R-HSA-9006335,Signaling by Erythropoietin,0.48460853,ENSG00000213281,1
R-HSA-114452,Activation of BH3-only proteins,0.49428912,ENSG00000101412,1
R-HSA-5626467,RHO GTPases activate IQGAPs,0.49428912,ENSG00000123416,1
R-HSA-1250196,SHC1 events in ERBB2 signaling,0.49428912,ENSG00000213281,1
R-HSA-5654716,Downstream signaling of activated FGFR4,0.49428912,ENSG00000213281,1
R-HSA-162710,Synthesis of glycosylphosphatidylinositol (GPI),0.49428912,ENSG00000163964,1
R-HSA-2424491,DAP12 signaling,0.49428912,ENSG00000213281,1
R-HSA-2173789,TGF-beta receptor signaling activates SMADs,0.49428912,ENSG00000186298,1
R-HSA-6802957,Oncogenic MAPK signaling,0.502253051,ENSG00000177674;ENSG00000213281,2
R-HSA-1912408,Pre-NOTCH Transcription and Translation,0.502253051,ENSG00000164032;ENSG00000101412,2
R-HSA-162588,Budding and maturation of HIV virion,0.503788533,ENSG00000196262,1
R-HSA-5673000,RAF activation,0.503788533,ENSG00000213281,1
R-HSA-186763,Downstream signal transduction,0.503788533,ENSG00000213281,1
R-HSA-5357801,Programmed Cell Death,0.512349016,ENSG00000101412;ENSG00000113368;ENSG00000164104;ENSG00000115233,4
R-HSA-111465,Apoptotic cleavage of cellular proteins,0.513110148,ENSG00000113368,1
R-HSA-9013694,Signaling by NOTCH4,0.519851443,ENSG00000013810;ENSG00000115233,2
R-HSA-8939243,RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known,0.522257281,ENSG00000136518,1
R-HSA-442742,CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling,0.522257281,ENSG00000213281,1
R-HSA-3781860,Diseases associated with N-glycosylation of proteins,0.522257281,ENSG00000088035,1
R-HSA-4090294,SUMOylation of intracellular receptors,0.531233185,ENSG00000188612,1
R-HSA-5637815,Signaling by Ligand-Responsive EGFR Variants in Cancer,0.531233185,ENSG00000213281,1
R-HSA-1236382,Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants,0.531233185,ENSG00000213281,1
R-HSA-8939211,ESR-mediated signaling,0.532765024,ENSG00000110958;ENSG00000182481;ENSG00000164032;ENSG00000213281,5
R-HSA-5663213,RHO GTPases Activate WASPs and WAVEs,0.540041055,ENSG00000112290,1
R-HSA-190861,Gap junction assembly,0.540041055,ENSG00000123416,1
R-HSA-5689880,Ub-specific processing proteases,0.547341238,ENSG00000117399;ENSG00000145604;ENSG00000175792;ENSG00000115233,4
R-HSA-5654696,Downstream signaling of activated FGFR2,0.548684024,ENSG00000213281,1
R-HSA-5654687,Downstream signaling of activated FGFR1,0.548684024,ENSG00000213281,1
R-HSA-187687,Signalling to ERKs,0.548684024,ENSG00000213281,1
R-HSA-111933,Calmodulin induced events,0.548684024,ENSG00000182481,1
R-HSA-111997,CaM pathway,0.548684024,ENSG00000182481,1
R-HSA-5655332,Signaling by FGFR3 in disease,0.548684024,ENSG00000213281,1
R-HSA-163560,Triglyceride catabolism,0.548684024,ENSG00000186298,1
R-HSA-8853338,Signaling by FGFR3 point mutants in cancer,0.548684024,ENSG00000213281,1
R-HSA-110328,Recognition and association of DNA glycosylase with site containing an affected pyrimidine,0.548684024,ENSG00000164032,1
R-HSA-983168,Antigen processing: Ubiquitination & Proteasome degradation,0.549298315,ENSG00000117399;ENSG00000175063;ENSG00000145604;ENSG00000165501;ENSG00000115233;ENSG00000170633,6
R-HSA-432720,Lysosome Vesicle Biogenesis,0.55716517,ENSG00000134262,1
R-HSA-3899300,SUMOylation of transcription cofactors,0.56548751,ENSG00000188612,1
R-HSA-196757,Metabolism of folate and pterines,0.56548751,ENSG00000120254,1
R-HSA-73887,Death Receptor Signalling,0.571176989,ENSG00000275700;ENSG00000142856;ENSG00000114346,3
R-HSA-5675221,Negative regulation of MAPK pathway,0.581667572,ENSG00000213281,1
R-HSA-9664565,Signaling by ERBB2 KD Mutants,0.581667572,ENSG00000213281,1
R-HSA-749476,RNA Polymerase III Abortive And Retractive Initiation,0.581667572,ENSG00000138385,1
R-HSA-74158,RNA Polymerase III Transcription,0.581667572,ENSG00000138385,1
R-HSA-73779,RNA Polymerase II Transcription Pre-Initiation And Promoter Opening,0.589531055,ENSG00000148835,1
R-HSA-9646399,Aggrephagy,0.589531055,ENSG00000123416,1
R-HSA-1643713,Signaling by EGFR in Cancer,0.589531055,ENSG00000213281,1
R-HSA-1227990,Signaling by ERBB2 in Cancer,0.589531055,ENSG00000213281,1
R-HSA-111996,Ca-dependent events,0.589531055,ENSG00000182481,1
R-HSA-8853884,Transcriptional Regulation by VENTX,0.589531055,ENSG00000175063,1
R-HSA-8939236,RUNX1 regulates transcription of genes involved in differentiation of HSCs,0.596342806,ENSG00000164032;ENSG00000115233,2
R-HSA-9609736,Assembly and cell surface presentation of NMDA receptors,0.597247257,ENSG00000123416,1
R-HSA-6811434,COPI-dependent Golgi-to-ER retrograde traffic,0.601444265,ENSG00000123416;ENSG00000161800,2
R-HSA-5625886,Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3,0.604818928,ENSG00000164032,1
R-HSA-381340,Transcriptional regulation of white adipocyte differentiation,0.606497133,ENSG00000135446;ENSG00000133398,2
R-HSA-211733,Regulation of activated PAK-2p34 by proteasome mediated degradation,0.612248764,ENSG00000115233,1
R-HSA-350562,Regulation of ornithine decarboxylase (ODC),0.619539414,ENSG00000115233,1
R-HSA-5654743,Signaling by FGFR4,0.619539414,ENSG00000213281,1
R-HSA-110329,Cleavage of the damaged pyrimidine ,0.619539414,ENSG00000164032,1
R-HSA-73928,Depyrimidination,0.619539414,ENSG00000164032,1
R-HSA-1433557,Signaling by SCF-KIT,0.619539414,ENSG00000213281,1
R-HSA-72766,Translation,0.620556939,ENSG00000162396;ENSG00000116120;ENSG00000106105;ENSG00000166986;ENSG00000111361;ENSG00000115211,6
R-HSA-167161,HIV Transcription Initiation,0.626693474,ENSG00000148835,1
R-HSA-75953,RNA Polymerase II Transcription Initiation,0.626693474,ENSG00000148835,1
R-HSA-167162,RNA Polymerase II HIV Promoter Escape,0.626693474,ENSG00000148835,1
R-HSA-6802948,Signaling by high-kinase activity BRAF mutants,0.626693474,ENSG00000213281,1
R-HSA-190828,Gap junction trafficking,0.626693474,ENSG00000123416,1
R-HSA-1489509,DAG and IP3 signaling,0.626693474,ENSG00000182481,1
R-HSA-6807070,PTEN Regulation,0.6287579,ENSG00000102054;ENSG00000162521;ENSG00000115233,3
R-HSA-1912422,Pre-NOTCH Expression and Processing,0.631033963,ENSG00000164032;ENSG00000101412,2
R-HSA-73776,RNA Polymerase II Promoter Escape,0.633713495,ENSG00000148835,1
R-HSA-180534,Vpu mediated degradation of CD4,0.633713495,ENSG00000115233,1
R-HSA-1236978,Cross-presentation of soluble exogenous antigens (endosomes),0.633713495,ENSG00000115233,1
R-HSA-5654741,Signaling by FGFR3,0.633713495,ENSG00000213281,1
R-HSA-2172127,DAP12 interactions,0.633713495,ENSG00000213281,1
R-HSA-71387,Metabolism of carbohydrates,0.633736742,ENSG00000125450;ENSG00000113569;ENSG00000132182;ENSG00000075188;ENSG00000095319;ENSG00000111581;ENSG00000120253;ENSG00000058804,8
R-HSA-6802949,Signaling by RAS mutants,0.64060198,ENSG00000213281,1
R-HSA-6802946,Signaling by moderate kinase activity BRAF mutants,0.64060198,ENSG00000213281,1
R-HSA-9649948,Signaling downstream of RAS mutants,0.64060198,ENSG00000213281,1
R-HSA-69601,Ubiquitin Mediated Degradation of Phosphorylated Cdc25A,0.64060198,ENSG00000115233,1
R-HSA-69610,p53-Independent DNA Damage Response,0.64060198,ENSG00000115233,1
R-HSA-69613,p53-Independent G1/S DNA damage checkpoint,0.64060198,ENSG00000115233,1
R-HSA-349425,Autodegradation of the E3 ubiquitin ligase COP1,0.64060198,ENSG00000115233,1
R-HSA-169911,Regulation of Apoptosis,0.64060198,ENSG00000115233,1
R-HSA-6802955,Paradoxical activation of RAF signaling by kinase inactive BRAF,0.647361383,ENSG00000213281,1
R-HSA-76042,RNA Polymerase II Transcription Initiation And Promoter Clearance,0.647361383,ENSG00000148835,1
R-HSA-437239,Recycling pathway of L1,0.647361383,ENSG00000123416,1
R-HSA-6781823,Formation of TC-NER Pre-Incision Complex,0.653994116,ENSG00000205581,1
R-HSA-180585,Vif-mediated degradation of APOBEC3G,0.653994116,ENSG00000115233,1
R-HSA-450408,AUF1 (hnRNP D0) binds and destabilizes mRNA,0.653994116,ENSG00000115233,1
R-HSA-157858,Gap junction trafficking and regulation,0.653994116,ENSG00000123416,1
R-HSA-4641258,Degradation of DVL,0.660502542,ENSG00000115233,1
R-HSA-4641257,Degradation of AXIN,0.660502542,ENSG00000115233,1
R-HSA-8941858,Regulation of RUNX3 expression and activity,0.660502542,ENSG00000115233,1
R-HSA-2162123,Synthesis of Prostaglandins (PG) and Thromboxanes (TX),0.666888984,ENSG00000110958,1
R-HSA-5655302,Signaling by FGFR1 in disease,0.666888984,ENSG00000213281,1
R-HSA-69541,Stabilization of p53,0.67315572,ENSG00000115233,1
R-HSA-177929,Signaling by EGFR,0.679304984,ENSG00000213281,1
R-HSA-5610787,Hedgehog 'off' state,0.680797941,ENSG00000123416;ENSG00000115233,2
R-HSA-432722,Golgi Associated Vesicle Biogenesis,0.685338972,ENSG00000134262,1
R-HSA-8866654,E3 ubiquitin ligases ubiquitinate target proteins,0.685338972,ENSG00000132646,1
R-HSA-5362768,Hh mutants that don't undergo autocatalytic processing are degraded by ERAD,0.685338972,ENSG00000115233,1
R-HSA-5676590,NIK-->noncanonical NF-kB signaling,0.685338972,ENSG00000115233,1
R-HSA-109606,Intrinsic Pathway for Apoptosis,0.685338972,ENSG00000101412,1
R-HSA-4420097,VEGFA-VEGFR2 Pathway,0.689235386,ENSG00000112290;ENSG00000213281,2
R-HSA-5610780,Degradation of GLI1 by the proteasome,0.691259837,ENSG00000115233,1
R-HSA-5610783,Degradation of GLI2 by the proteasome,0.691259837,ENSG00000115233,1
R-HSA-5610785,GLI3 is processed to GLI3R by the proteasome,0.691259837,ENSG00000115233,1
R-HSA-5654736,Signaling by FGFR1,0.691259837,ENSG00000213281,1
R-HSA-5674135,MAP2K and MAPK activation,0.697069691,ENSG00000213281,1
R-HSA-6811436,COPI-independent Golgi-to-ER retrograde traffic,0.697069691,ENSG00000123416,1
R-HSA-9012852,Signaling by NOTCH3,0.697069691,ENSG00000013810,1
R-HSA-983705,Signaling by the B Cell Receptor (BCR),0.701397078,ENSG00000196262;ENSG00000213281;ENSG00000115233,3
R-HSA-5387390,Hh mutants abrogate ligand secretion,0.702770609,ENSG00000115233,1
R-HSA-5655253,Signaling by FGFR2 in disease,0.702770609,ENSG00000213281,1
R-HSA-72737,Cap-dependent Translation Initiation,0.705561206,ENSG00000111361;ENSG00000115211,2
R-HSA-72613,Eukaryotic Translation Initiation,0.705561206,ENSG00000111361;ENSG00000115211,2
R-HSA-112399,IRS-mediated signalling,0.708364625,ENSG00000213281,1
R-HSA-5693565,Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks,0.713853737,ENSG00000137337,1
R-HSA-4608870,Asymmetric localization of PCP proteins,0.713853737,ENSG00000115233,1
R-HSA-5607761,Dectin-1 mediated noncanonical NF-kB signaling,0.713853737,ENSG00000115233,1
R-HSA-8979227,Triglyceride metabolism,0.713853737,ENSG00000186298,1
R-HSA-157118,Signaling by NOTCH,0.71741731,ENSG00000013810;ENSG00000164032;ENSG00000101412;ENSG00000115233,4
R-HSA-5678895,Defective CFTR causes cystic fibrosis,0.719239906,ENSG00000115233,1
R-HSA-8956321,Nucleotide salvage,0.724525054,ENSG00000167900,1
R-HSA-194138,Signaling by VEGF,0.724960064,ENSG00000112290;ENSG00000213281,2
R-HSA-2428928,IRS-related events triggered by IGF1R,0.72971107,ENSG00000213281,1
R-HSA-163841,"Gamma carboxylation, hypusine formation and arylsulfatase activation",0.72971107,ENSG00000132768,1
R-HSA-114608,Platelet degranulation ,0.732412938,ENSG00000138430;ENSG00000196262,2
R-HSA-112043,PLC beta mediated events,0.734799806,ENSG00000182481,1
R-HSA-375165,NCAM signaling for neurite out-growth,0.734799806,ENSG00000213281,1
R-HSA-186797,Signaling by PDGF,0.734799806,ENSG00000213281,1
R-HSA-112040,G-protein mediated events,0.739793081,ENSG00000182481,1
R-HSA-2428924,IGF1R signaling cascade,0.744692679,ENSG00000213281,1
R-HSA-1169091,Activation of NF-kappaB in B cells,0.744692679,ENSG00000115233,1
R-HSA-1234176,Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha,0.744692679,ENSG00000115233,1
R-HSA-74751,Insulin receptor signalling cascade,0.744692679,ENSG00000213281,1
R-HSA-5358346,Hedgehog ligand biogenesis,0.744692679,ENSG00000115233,1
R-HSA-2404192,Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R),0.749500351,ENSG00000213281,1
R-HSA-8948751,Regulation of PTEN stability and activity,0.754217815,ENSG00000115233,1
R-HSA-194840,Rho GTPase cycle,0.757161594,ENSG00000114346;ENSG00000161800,2
R-HSA-76005,Response to elevated platelet cytosolic Ca2+,0.757161594,ENSG00000138430;ENSG00000196262,2
R-HSA-8856688,Golgi-to-ER retrograde transport,0.770400164,ENSG00000123416;ENSG00000161800,2
R-HSA-2132295,MHC class II antigen presentation,0.770400164,ENSG00000123416;ENSG00000161800,2
R-HSA-8936459,RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function,0.77221886,ENSG00000164032,1
R-HSA-1227986,Signaling by ERBB2,0.77221886,ENSG00000213281,1
R-HSA-201681,TCF dependent signaling in response to WNT,0.776381174,ENSG00000164032;ENSG00000175792;ENSG00000115233,3
R-HSA-5625740,RHO GTPases activate PKNs,0.78072052,ENSG00000164032,1
R-HSA-199992,trans-Golgi Network Vesicle Budding,0.78072052,ENSG00000134262,1
R-HSA-351202,Metabolism of polyamines,0.78072052,ENSG00000115233,1
R-HSA-167172,Transcription of the HIV genome,0.784852035,ENSG00000148835,1
R-HSA-9663891,Selective autophagy,0.792883824,ENSG00000123416,1
R-HSA-917937,Iron uptake and transport,0.792883824,ENSG00000108010,1
R-HSA-416482,G alpha (12/13) signalling events,0.800616832,ENSG00000114346,1
R-HSA-1234174,Cellular response to hypoxia,0.800616832,ENSG00000115233,1
R-HSA-170834,Signaling by TGF-beta Receptor Complex,0.800616832,ENSG00000186298,1
R-HSA-1655829,Regulation of cholesterol biosynthesis by SREBP (SREBF),0.80437477,ENSG00000132341,1
R-HSA-1643685,Disease,0.806055625,ENSG00000108468;ENSG00000196262;ENSG00000095002;ENSG00000152422;ENSG00000135446;ENSG00000115233;ENSG00000182481;ENSG00000116062;ENSG00000168496;ENSG00000213281;ENSG00000095319;ENSG00000088035;ENSG00000120253;ENSG00000058804;ENSG00000102054;ENSG00000177674;ENSG00000125450;ENSG00000113569;ENSG00000075188;ENSG00000132341;ENSG00000132781;ENSG00000113368;ENSG00000111581;ENSG00000148835;ENSG00000123416;ENSG00000132182;ENSG00000101224;ENSG00000162521;ENSG00000105486,30
R-HSA-674695,RNA Polymerase II Pre-transcription Events,0.811680244,ENSG00000148835,1
R-HSA-5654738,Signaling by FGFR2,0.811680244,ENSG00000213281,1
R-HSA-6806834,Signaling by MET,0.811680244,ENSG00000213281,1
R-HSA-977225,Amyloid fiber formation,0.811680244,ENSG00000164032,1
R-HSA-112314,Neurotransmitter receptors and postsynaptic signal transmission,0.815768769,ENSG00000182481;ENSG00000123416;ENSG00000213281,3
R-HSA-195253,Degradation of beta-catenin by the destruction complex,0.822131892,ENSG00000115233,1
R-HSA-5632684,Hedgehog 'on' state,0.825485707,ENSG00000115233,1
R-HSA-5358351,Signaling by Hedgehog,0.827554416,ENSG00000123416;ENSG00000115233,2
R-HSA-187037,Signaling by NTRK1 (TRKA),0.828776512,ENSG00000213281,1
R-HSA-450531,Regulation of mRNA stability by proteins that bind AU-rich elements,0.828776512,ENSG00000115233,1
R-HSA-6807505,RNA polymerase II transcribes snRNA genes,0.832005485,ENSG00000148835,1
R-HSA-1226099,Signaling by FGFR in disease,0.832005485,ENSG00000213281,1
R-HSA-74752,Signaling by Insulin receptor,0.841332883,ENSG00000213281,1
R-HSA-5619084,ABC transporter disorders,0.847262646,ENSG00000115233,1
R-HSA-4086400,PCP/CE pathway,0.847262646,ENSG00000115233,1
R-HSA-9006931,Signaling by Nuclear Receptors,0.854794448,ENSG00000110958;ENSG00000182481;ENSG00000164032;ENSG00000213281,5
R-HSA-5668541,TNFR2 non-canonical NF-kB pathway,0.861138773,ENSG00000115233,1
R-HSA-400253,Circadian Clock,0.861138773,ENSG00000186298,1
R-HSA-9010553,Regulation of expression of SLITs and ROBOs,0.861680301,ENSG00000115233;ENSG00000141543,2
R-HSA-422356,Regulation of insulin secretion,0.86633083,ENSG00000277443,1
R-HSA-5687128,MAPK6/MAPK4 signaling,0.86633083,ENSG00000115233,1
R-HSA-6807878,COPI-mediated anterograde transport,0.868853861,ENSG00000123416,1
R-HSA-190236,Signaling by FGFR,0.868853861,ENSG00000213281,1
R-HSA-8878171,Transcriptional regulation by RUNX1,0.872256758,ENSG00000136518;ENSG00000164032;ENSG00000115233,3
R-HSA-9020702,Interleukin-1 signaling,0.873758456,ENSG00000115233,1
R-HSA-983169,Class I MHC mediated antigen processing & presentation,0.875410373,ENSG00000117399;ENSG00000175063;ENSG00000145604;ENSG00000165501;ENSG00000115233;ENSG00000170633,6
R-HSA-9009391,Extra-nuclear estrogen signaling,0.876141783,ENSG00000213281,1
R-HSA-111885,Opioid Signalling,0.878480277,ENSG00000182481,1
R-HSA-9006936,Signaling by TGF-beta family members,0.885235083,ENSG00000186298,1
R-HSA-163125,Post-translational modification: synthesis of GPI-anchored proteins,0.887402491,ENSG00000163964,1
R-HSA-166520,Signaling by NTRKs,0.893663045,ENSG00000213281,1
R-HSA-8878159,Transcriptional regulation by RUNX3,0.893663045,ENSG00000115233,1
R-HSA-5621481,C-type lectin receptors (CLRs),0.897601703,ENSG00000213281;ENSG00000115233,2
R-HSA-5607764,CLEC7A (Dectin-1) signaling,0.897642826,ENSG00000115233,1
R-HSA-382556,ABC-family proteins mediated transport,0.901474185,ENSG00000115233,1
R-HSA-975957,Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC),0.905162637,ENSG00000141543,1
R-HSA-927802,Nonsense-Mediated Decay (NMD),0.905162637,ENSG00000141543,1
R-HSA-2871796,FCERI mediated MAPK activation,0.905162637,ENSG00000213281,1
R-HSA-202424,Downstream TCR signaling,0.905162637,ENSG00000115233,1
R-HSA-9006925,Intracellular signaling by second messengers,0.912666936,ENSG00000102054;ENSG00000182481;ENSG00000162521;ENSG00000115233,4
R-HSA-373760,L1CAM interactions,0.915422689,ENSG00000123416,1
R-HSA-6811442,Intra-Golgi and retrograde Golgi-to-ER traffic,0.918636357,ENSG00000123416;ENSG00000161800,2
R-HSA-1632852,Macroautophagy,0.935263932,ENSG00000123416,1
R-HSA-163685,Integration of energy metabolism,0.936489056,ENSG00000277443,1
R-HSA-376176,Signaling by ROBO receptors,0.937555902,ENSG00000115233;ENSG00000141543,2
R-HSA-2454202,Fc epsilon receptor (FCERI) signaling,0.937555902,ENSG00000213281;ENSG00000115233,2
R-HSA-202403,TCR signaling,0.938870432,ENSG00000115233,1
R-HSA-2980736,Peptide hormone metabolism,0.938870432,ENSG00000180104,1
R-HSA-1257604,PIP3 activates AKT signaling,0.938976316,ENSG00000102054;ENSG00000162521;ENSG00000115233,3
R-HSA-6798695,Neutrophil degranulation,0.95037399,ENSG00000196262;ENSG00000213281;ENSG00000166226;ENSG00000149636;ENSG00000115233,5
R-HSA-2029482,Regulation of actin dynamics for phagocytic cup formation,0.950463542,ENSG00000112290,1
R-HSA-195721,Signaling by WNT,0.951227905,ENSG00000164032;ENSG00000175792;ENSG00000115233,3
R-HSA-446193,"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein",0.951401926,ENSG00000088035,1
R-HSA-9612973,Autophagy,0.952322597,ENSG00000123416,1
R-HSA-196849,Metabolism of water-soluble vitamins and cofactors,0.95375715,ENSG00000125454;ENSG00000120254,2
R-HSA-446652,Interleukin-1 family signaling,0.954981638,ENSG00000115233,1
R-HSA-199977,ER to Golgi Anterograde Transport,0.95583473,ENSG00000123416,1
R-HSA-202733,Cell surface interactions at the vascular wall,0.955917034,ENSG00000196262;ENSG00000213281,2
R-HSA-1236974,ER-Phagosome pathway,0.956671714,ENSG00000115233,1
R-HSA-3858494,Beta-catenin independent WNT signaling,0.957492893,ENSG00000115233,1
R-HSA-2142753,Arachidonic acid metabolism,0.957492893,ENSG00000110958,1
R-HSA-1989781,PPARA activates gene expression,0.963527892,ENSG00000133398,1
R-HSA-112315,Transmission across Chemical Synapses,0.963853544,ENSG00000182481;ENSG00000123416;ENSG00000213281,3
R-HSA-2871837,FCERI mediated NF-kB activation,0.964219561,ENSG00000115233,1
R-HSA-400206,Regulation of lipid metabolism by PPARalpha,0.964898161,ENSG00000133398,1
R-HSA-2408522,Selenoamino acid metabolism,0.968103564,ENSG00000166986,1
R-HSA-1280215,Cytokine Signaling in Immune system,0.969264336,ENSG00000125450;ENSG00000196262;ENSG00000113569;ENSG00000075188;ENSG00000113368;ENSG00000111581;ENSG00000115233;ENSG00000182481;ENSG00000132182;ENSG00000213281;ENSG00000095319;ENSG00000120253;ENSG00000141543;ENSG00000058804,16
R-HSA-1236975,Antigen processing-Cross presentation,0.97156733,ENSG00000115233,1
R-HSA-5673001,RAF/MAP kinase cascade,0.974124638,ENSG00000213281;ENSG00000115233,2
R-HSA-2029480,Fcgamma receptor (FCGR) dependent phagocytosis,0.974656178,ENSG00000112290,1
R-HSA-76002,"Platelet activation, signaling and aggregation",0.975361864,ENSG00000138430;ENSG00000196262,2
R-HSA-5684996,MAPK1/MAPK3 signaling,0.976923101,ENSG00000213281;ENSG00000115233,2
R-HSA-3781865,Diseases of glycosylation,0.978673759,ENSG00000088035,1
R-HSA-9607240,FLT3 Signaling,0.981670179,ENSG00000213281;ENSG00000115233,2
R-HSA-948021,Transport to the Golgi and subsequent modification,0.984611441,ENSG00000123416,1
R-HSA-8957322,Metabolism of steroids,0.984723039,ENSG00000132341;ENSG00000188612,2
R-HSA-109582,Hemostasis,0.988609255,ENSG00000138430;ENSG00000196262;ENSG00000123416;ENSG00000213281;ENSG00000108384;ENSG00000161800;ENSG00000123374;ENSG00000149679,8
R-HSA-5683057,MAPK family signaling cascades,0.990107876,ENSG00000213281;ENSG00000115233,2
R-HSA-1280218,Adaptive Immune System,0.992337608,ENSG00000117399;ENSG00000175063;ENSG00000145604;ENSG00000196262;ENSG00000123416;ENSG00000213281;ENSG00000161800;ENSG00000165501;ENSG00000115233;ENSG00000170633,10
R-HSA-9006934,Signaling by Receptor Tyrosine Kinases,0.993494264,ENSG00000112290;ENSG00000213281;ENSG00000117632,4
R-HSA-449147,Signaling by Interleukins,0.993716805,ENSG00000196262;ENSG00000113368;ENSG00000115233,5
R-HSA-196854,Metabolism of vitamins and cofactors,0.994439253,ENSG00000125454;ENSG00000120254,2
R-HSA-416476,G alpha (q) signalling events,0.995510964,ENSG00000213281,1
R-HSA-422475,Axon guidance,0.995817579,ENSG00000123416;ENSG00000213281;ENSG00000115233;ENSG00000141543,4
R-HSA-5663202,Diseases of signal transduction,0.995875758,ENSG00000177674;ENSG00000213281;ENSG00000115233,3
R-HSA-112316,Neuronal System,0.99606725,ENSG00000182481;ENSG00000123416;ENSG00000213281,3
R-HSA-1266738,Developmental Biology,0.99636857,ENSG00000102054;ENSG00000123416;ENSG00000164032;ENSG00000213281;ENSG00000101412;ENSG00000135446;ENSG00000123374;ENSG00000162521;ENSG00000115233;ENSG00000141543;ENSG00000133398;ENSG00000124795,12
R-HSA-211945,Phase I - Functionalization of compounds,0.996639515,ENSG00000110958,1
R-HSA-446203,Asparagine N-linked glycosylation,0.997154985,ENSG00000123416;ENSG00000088035,2
R-HSA-199991,Membrane Trafficking,0.998776863,ENSG00000180104;ENSG00000134262;ENSG00000123416;ENSG00000161800,4
R-HSA-8978868,Fatty acid metabolism,0.999735474,ENSG00000110958,1
R-HSA-5653656,Vesicle-mediated transport,0.99990372,ENSG00000180104;ENSG00000134262;ENSG00000123416;ENSG00000161800,4
R-HSA-71291,Metabolism of amino acids and derivatives,0.999960271,ENSG00000166986;ENSG00000115233,2
R-HSA-211859,Biological oxidations,0.999972692,ENSG00000110958,1
R-HSA-418594,G alpha (i) signalling events,0.999982286,ENSG00000182481,1
R-HSA-162582,Signal Transduction,0.999991292,ENSG00000072864;ENSG00000114346;ENSG00000135446;ENSG00000117632;ENSG00000115233;ENSG00000117399;ENSG00000013810;ENSG00000122952;ENSG00000182481;ENSG00000151725;ENSG00000164032;ENSG00000213281;ENSG00000101412;ENSG00000161800;ENSG00000149636;ENSG00000120253;ENSG00000102054;ENSG00000110958;ENSG00000125450;ENSG00000154473;ENSG00000175792;ENSG00000075188;ENSG00000175216;ENSG00000111581;ENSG00000275700;ENSG00000123416;ENSG00000112290;ENSG00000031691;ENSG00000186298;ENSG00000142856;ENSG00000123374;ENSG00000149503;ENSG00000162521,35
R-HSA-168256,Immune System,0.999998044,ENSG00000175063;ENSG00000125450;ENSG00000196262;ENSG00000113569;ENSG00000075188;ENSG00000113368;ENSG00000111581;ENSG00000115233;ENSG00000170633;ENSG00000117399;ENSG00000145604;ENSG00000182481;ENSG00000123416;ENSG00000132182;ENSG00000112290;ENSG00000213281;ENSG00000095319;ENSG00000165501;ENSG00000161800;ENSG00000166226;ENSG00000149636;ENSG00000141543;ENSG00000120253;ENSG00000058804,26
R-HSA-168249,Innate Immune System,0.999999432,ENSG00000196262;ENSG00000112290;ENSG00000213281;ENSG00000166226;ENSG00000149636;ENSG00000115233,6
R-HSA-382551,Transport of small molecules,0.999999867,ENSG00000108010;ENSG00000115233,2
R-HSA-556833,Metabolism of lipids,0.999999988,ENSG00000110958;ENSG00000186298;ENSG00000132341;ENSG00000188612;ENSG00000133398,5
R-HSA-388396,GPCR downstream signalling,0.999999999,ENSG00000182481;ENSG00000213281;ENSG00000114346,3
R-HSA-372790,Signaling by GPCR,1,ENSG00000182481;ENSG00000213281;ENSG00000114346,3
R-HSA-1430728,Metabolism,1,ENSG00000176890;ENSG00000115233;ENSG00000062822;ENSG00000167325;ENSG00000095319;ENSG00000167900;ENSG00000120253;ENSG00000058804;ENSG00000120254;ENSG00000110958;ENSG00000125450;ENSG00000113569;ENSG00000075188;ENSG00000132341;ENSG00000111581;ENSG00000133398;ENSG00000138363;ENSG00000171848;ENSG00000132182;ENSG00000186298;ENSG00000188612;ENSG00000166986;ENSG00000277443;ENSG00000125454;ENSG00000163655,25