Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR
GOTERM_CC_DIRECT,GO:0070062~extracellular exosome,170,37.94642857,1.01E-33,"FHIT, ALAD, CADM4, SLC22A13, THRB, SLC22A12, SLC44A4, SLC9A3, SLC7A8, BPHL, TSPAN8, SELENBP1, CALB1, AQP2, PRKAR2B, GSTM3, PVALB, TMEM52B, MIOX, GP2, AIF1L, RAB25, SLC4A1, RAPGEF3, F11, ALDH6A1, LAD1, SUCLG1, FBP1, NAPSA, PTPRO, NAPEPLD, RHCG, TACSTD2, ABAT, SH3GL2, WFDC2, FAM171A1, SMIM24, ENPP6, ACADSB, ASS1, PKHD1, ALDOB, PTH1R, UMOD, AGMAT, ATP6V1B1, GPD1L, ALB, FOLR1, ANGPTL1, NDRG2, EGF, DEFB1, MUC1, PLAT, CPNE6, EPHX2, C16ORF89, PTPN13, ABCB1, SLC6A19, ACPP, CEL, DNASE1, GGT6, C1ORF116, SFRP1, FAM151A, FREM2, PLCG2, CYFIP2, SLC13A2, QPRT, PAPPA2, SLC13A3, DCXR, MYH10, SLC5A2, MYO7B, SLC15A2, FGF9, FAM3B, NPNT, SUSD2, SAT2, BCAM, EPCAM, EFHD1, SLC23A1, GPC3, SERPINA5, PROZ, ACOT11, SLC22A6, TREH, DPP6, ATP6V0D2, CEACAM1, DPEP1, HPD, KNG1, HYAL1, DDC, PEPD, SLC22A8, PIGR, WLS, SLIT2, SLC26A4, ATP6V1C2, CTH, CLIC5, SCIN, HAO2, CNTN1, PLLP, CTSH, CHL1, C7, SORD, MAL2, FUT6, ADH6, PBLD, PRSS8, IGSF11, ANXA9, HSPA2, KRT7, SULT1C2, SUCNR1, HRG, NEDD4L, SCNN1G, PLA2R1, SCNN1B, SCNN1A, COBLL1, PTPRD, CR2, SLC12A1, KL, SLC12A3, TMC4, HOGA1, NFASC, ATP1A1, KLK1, PCK2, MAN1C1, PLG, ANXA3, PCK1, XPNPEP2, PROM1, CYP4A11, AFM, PROM2, CDH16, IRF6, FBLN5, NPHS2, NPHS1, PHGDH, PSAT1, IGFBP2, ATP6V0A4, HPGD",434,2811,18224,2.539463956,3.01E-31,3.01E-31,1.34E-30
GOTERM_CC_DIRECT,GO:0016324~apical plasma membrane,44,9.821428571,4.39E-22,"SHROOM3, SLC22A13, MAL2, SLC22A12, PKHD1, SLC9A3, ERBB2, PTH1R, SLC7A9, UMOD, ATP6V1B1, SLC52A3, AQP2, EPCAM, SLC23A1, ANK2, MARVELD2, FOLR1, TRPV5, SCNN1G, SCNN1B, SCNN1A, ATP6V0D2, DPEP1, CEACAM1, MUC1, TRPM6, SLC12A1, SLC12A3, KL, SLC34A1, MAL, ATP1A1, ABCB1, PTPRO, SLC26A4, PROM1, CYP4A11, PROM2, RHCG, SPTBN2, CYP4F2, IGFBP2, ATP6V0A4",434,291,18224,6.34912189,1.31E-19,6.56E-20,5.86E-19
GOTERM_CC_DIRECT,GO:0016323~basolateral plasma membrane,28,6.25,2.05E-14,"CLDN8, ENPP1, ERBB4, ERBB2, PTH1R, SLC7A8, RHBG, UMOD, KCNJ10, ATP12A, ATP6V1B1, AQP2, EPCAM, ANK2, ANK3, FOLR1, MARVELD2, SLC22A6, SLC4A1, SLC22A7, SLC22A8, ATP1A1, SLC4A11, PROM2, CDH16, RHCG, SLC26A7, HPGD",434,180,18224,6.531899642,6.14E-12,2.05E-12,2.74E-11
GOTERM_CC_DIRECT,GO:0005886~plasma membrane,162,36.16071429,2.99E-12,"CASR, SLC22A12, SLC44A4, SLC9A3, SLC9A2, SLC7A8, SLC7A9, L1CAM, SLC52A3, GLDC, AQP2, PRKAR2B, MCOLN3, ANK2, ANK3, GP2, SLC4A1, RAPGEF3, MUC15, F11, MAGI2, PLXNB1, SUCLG1, SLC34A1, C1ORF210, PTPRO, TMEM25, GRHL2, RHCG, PDGFRA, ATP6V1G3, GRB14, SH3GL2, FRAS1, SLC2A12, ABCA8, FGFR2, ENPP6, FXYD4, ENPP1, ERBB4, ERBB2, PTH1R, ATP12A, KCNJ1, LLGL2, PAQR5, GPD1L, SLC48A1, FOLR1, TMEM30B, SLC30A2, EGF, GABRA2, IL1RL1, CPNE6, NTN4, PTPN13, ABCB1, SLC6A19, ACPP, NPY5R, SFRP1, SEMA6D, FREM2, PLCG2, SLC13A2, SLC13A3, DIO1, DCXR, MYH10, CLDN8, SLC5A2, KCNJ15, ADGRF1, SLC15A2, SUSD2, KCNJ10, BCAM, KCNIP1, EPCAM, SLC23A1, GPC3, TRPV5, ANO5, STRA6, SLC22A6, TREH, SCN7A, DPP6, CEACAM1, DPEP1, KNG1, ZDHHC2, TRPM3, TRPM6, PARM1, PIK3C2G, PTGER3, SLC22A7, SLC22A8, PIGR, OXGR1, WLS, SLIT2, SLC26A4, SLC26A7, EPB41L5, CNTN1, SORT1, CNTN3, ARL4D, RASD1, CHL1, CLDN16, PLPP4, RHBG, CLCNKB, GPM6B, CLDN10, KIT, CDH3, SLC47A2, PRSS8, IGSF11, PLCL1, GPHN, STK32A, CDH9, TSPAN33, INPP5J, DNER, PLCD4, SUCNR1, HRG, NEDD4L, SLC4A9, SCNN1G, PLA2R1, SCNN1B, SCNN1A, PTPRD, CR2, SLC12A1, KL, SLC12A3, NFASC, ATP1A1, MAPK10, PLG, ANXA3, XPNPEP2, IYD, PROM1, CDH16, PRLR, SLC16A7, NPHS2, NPHS1, LIPH, BMPR1B, ATP6V0A4",434,4121,18224,1.650693257,8.93E-10,2.23E-10,3.99E-09
GOTERM_CC_DIRECT,GO:0005887~integral component of plasma membrane,76,16.96428571,3.16E-11,"TM7SF2, SLC5A2, KCNJ15, CASR, CADM4, SLC22A13, SLC15A2, SLC22A12, SLC7A8, SLC7A9, TSPAN7, TSPAN8, BCAM, KCNJ10, PLPPR1, SLC52A3, AQP2, KCNJ13, EPCAM, SLC23A1, GPC3, TRPV5, SLC22A6, SLC4A1, CEACAM1, ZDHHC2, PTGER3, PLXNB1, SLC22A7, SLC22A8, SCN2A, SLC34A1, PIGR, SLC7A13, PTPRO, SLC26A4, RHCG, SLC26A7, TACSTD2, PDGFRA, SLC2A12, FGFR2, PLPP4, FXYD4, ENPP1, PTH1R, RHBG, CLCNKB, TSPAN33, FOLR1, HS6ST1, SCNN1G, SLC4A9, SCNN1B, PLA2R1, SCNN1A, MUC1, PTPRD, KL, SLC12A3, MAL, SLC6A19, NPY5R, PROM1, CEL, SLC16A5, PROM2, SLC4A11, SEMA6D, SLC16A7, NPHS2, NPHS1, SLC13A2, SLC13A3, BMPR1B, CLCN5",434,1415,18224,2.255335363,9.45E-09,1.89E-09,4.22E-08
GOTERM_BP_DIRECT,GO:0007588~excretion,13,2.901785714,4.97E-11,"CLDN16, CLCNKB, UMOD, ATP6V1B1, AQP2, KCNJ1, NPHS2, NPHS1, SCNN1G, NEDD4L, SCNN1B, ATP6V0A4, CLCN5",418,37,16792,14.1145739,1.07E-07,1.07E-07,8.61E-08
KEGG_PATHWAY,hsa01100:Metabolic pathways,68,15.17857143,8.56E-08,"ACOX2, TM7SF2, ALAD, OGDHL, SAT2, ADH1C, ADH1B, GPAT3, GLDC, RGN, DAO, TREH, PDHA1, HADH, ATP6V0D2, HPD, HYAL1, DDC, ALDH6A1, PIK3C2G, SUCLG1, FBP1, ATP6V1C2, G6PC, CTH, HYKK, HAO2, ABAT, ATP6V1G3, ACAA1, ACADSB, SORD, ASS1, ENPP1, CYP2B6, FUT6, ALDOB, UPP2, ADH6, ATP6V1B1, AGMAT, PIPOX, INPP5J, PLCD4, ALDH4A1, BDH1, CHDH, NOS1, KL, HOGA1, EPHX2, PCK2, MAN1C1, PCK1, ACSM3, CEL, RDH10, CYP17A1, GGT6, HMGCS2, PLCG2, PHGDH, PRODH2, QPRT, CYP4F2, ATP6V0A4, PSAT1, DCXR",205,1219,6879,1.871874187,1.84E-05,1.84E-05,1.09E-04
GOTERM_BP_DIRECT,GO:0055078~sodium ion homeostasis,7,1.5625,9.41E-08,"CYP4A11, TFAP2B, SCNN1G, SCN7A, CYP4F2, SCNN1B, SCNN1A",418,11,16792,25.56415833,2.02E-04,1.01E-04,1.63E-04
GOTERM_CC_DIRECT,GO:0016021~integral component of membrane,171,38.16964286,4.63E-07,"CASR, SLC22A13, SLC22A12, SLC44A4, VTCN1, SLC9A3, SLC9A2, SLC7A8, TSPAN7, L1CAM, PLPPR1, GPAT3, AQP2, MCOLN3, PAPPA, TMEM52B, GP2, SMIM5, SLC4A1, SCD5, MUC15, HIGD1A, ATRNL1, SCN2A, SLC34A1, C1ORF210, PTPRO, TMEM25, TMEM207, CWH43, C14ORF37, RHCG, TACSTD2, HSD11B2, FAM171A1, FRAS1, ABCA8, SMIM24, FGFR2, ENPP1, ERBB4, PKHD1, ERBB2, PTH1R, MFSD4A, UMOD, SFXN2, ATP12A, TMEM178A, KCNJ1, PAQR5, SLC48A1, FOLR1, PACRG, TMEM30B, SLC30A2, NDRG2, EGF, MUC1, REEP6, GABRA2, IL1RL1, HRASLS2, ABCB1, SLC6A19, ACPP, GGT6, SLC4A11, RNF150, SFRP1, FAM151A, SEMA6D, FREM2, FREM1, SLC13A2, SLC13A3, DIO1, CLCN5, CLDN8, TM7SF2, SLC5A2, KCNJ15, ADGRF1, CLSTN2, SLC15A2, SUSD2, LRRC19, BCAM, KCNJ10, KCNJ13, EPCAM, TMEM174, TRPV5, ANO5, SLC22A6, STRA6, DPP6, LARGE2, CEACAM1, ZDHHC2, TRPM3, TRPM6, PARM1, PTGER3, CLMN, SLC22A7, SLC22A8, WLS, HEPACAM2, OXGR1, ST6GALNAC2, TMEM72, SLC26A4, G6PC, SLC26A7, SORT1, SUSD4, NRK, PLLP, CHL1, CLDN16, PLPP4, MAL2, FUT6, CTXN3, RHBG, CLCNKB, GPM6B, CLDN10, KIT, CDH3, UGT3A1, SLC47A2, FMO4, PRSS8, IGSF11, FMO5, CDH9, MARVELD2, SHISA3, TMEM252, DNER, HS6ST1, SUCNR1, PLA2R1, SCNN1B, SCNN1A, PTPRD, CR2, SLC12A1, TMEM45B, KL, SLC12A3, TMC4, HOGA1, NFASC, ATP1A1, MAL, IYD, TMPRSS4, PROM1, CYP4A11, SLC16A5, RDH10, PROM2, CDH16, PRLR, CYP4F2, CMTM4, BMPR1B, ATP6V0A4",434,5163,18224,1.390746458,1.38E-04,2.31E-05,6.18E-04
GOTERM_MF_DIRECT,GO:0015301~anion:anion antiporter activity,8,1.785714286,7.52E-07,"SLC26A4, SLC4A11, SLC26A7, SLC22A7, SLC22A8, SLC22A6, SLC4A1, SLC4A9",405,23,16881,14.4979066,5.28E-04,5.28E-04,0.001133987
GOTERM_CC_DIRECT,GO:0031526~brush border membrane,10,2.232142857,2.79E-06,"SLC26A4, TRPM6, FOLR1, SLC22A12, SLC9A3, PTH1R, SLC34A1, SLC7A9, ATP6V0A4, SLC6A19",434,51,18224,8.233486943,8.34E-04,1.19E-04,0.003725727
GOTERM_BP_DIRECT,GO:0001657~ureteric bud development,9,2.008928571,3.44E-06,"FGFR2, EPCAM, TCF21, SFRP1, LHX1, NPNT, WT1, SIM1, SLIT2",418,38,16792,9.51447998,0.007360108,0.002459413,0.005964592
GOTERM_BP_DIRECT,GO:0006814~sodium ion transport,12,2.678571429,4.94E-06,"SLC5A2, SLC23A1, SLC12A1, SLC4A11, SLC12A3, SCN2A, SLC13A2, SLC13A3, NEDD4L, SCNN1G, SCN7A, SCNN1B",418,81,16792,5.951444267,0.010547758,0.002647434,0.008561472
GOTERM_BP_DIRECT,GO:0034220~ion transmembrane transport,19,4.241071429,5.29E-06,"GABRA2, SLC12A1, FXYD4, CLCNKB, ATP1A1, SFXN2, ATP12A, ATP6V1B1, AQP2, ATP6V1C2, ANO5, NEDD4L, SCNN1G, ATP6V1G3, SCNN1B, ATP6V0A4, SCNN1A, ATP6V0D2, CLCN5",418,210,16792,3.634632035,0.011294284,0.002269131,0.009170842
GOTERM_BP_DIRECT,GO:0001822~kidney development,12,2.678571429,8.92E-06,"TCF21, ASS1, PKHD1, LHX1, GATA3, TFAP2B, SLC34A1, TFAP2A, RGN, STRA6, DCN, WT1",418,86,16792,5.605430066,0.018964001,0.003185935,0.015458011
KEGG_PATHWAY,hsa04960:Aldosterone-regulated sodium reabsorption,9,2.008928571,1.45E-05,"FXYD4, NR3C2, HSD11B2, ATP1A1, NEDD4L, SCNN1G, SCNN1B, SCNN1A, KCNJ1",205,39,6879,7.743714822,0.003121674,0.001562057,0.018441038
GOTERM_BP_DIRECT,GO:0006811~ion transport,14,3.125,1.66E-05,"CLDN16, GABRA2, SLC12A1, SLC15A2, SLC12A3, SLC9A3, SLC9A2, TMC4, CLDN10, SLC26A4, SLC26A7, WNK4, PLLP, PDZD3",418,127,16792,4.428436876,0.035002968,0.005077104,0.028764892
GOTERM_BP_DIRECT,GO:0014066~regulation of phosphatidylinositol 3-kinase signaling,11,2.455357143,2.23E-05,"FGFR2, ERBB4, KL, FGF9, ERBB2, PDGFRA, PTPN13, KIT, FGF1, EGF, CEACAM1",418,78,16792,5.665317139,0.046821688,0.005976232,0.038711555
GOTERM_BP_DIRECT,GO:0055114~oxidation-reduction process,33,7.366071429,3.33E-05,"TM7SF2, PHYHD1, ASPDH, SORD, CYP2B6, LDHD, PIPOX, GLDC, FMO4, GPD1L, FMO5, MIOX, ALDH4A1, DAO, SCD5, BDH1, HIGD1A, HPD, CHDH, ALDH6A1, NOS1, GMPR, IYD, CYP4A11, RDH10, CYP17A1, PHGDH, HSD11B2, PRODH2, DIO1, CYP4F2, HPGD, DCXR",418,592,16792,2.239331437,0.068942205,0.007905687,0.057661454
KEGG_PATHWAY,hsa04978:Mineral absorption,9,2.008928571,3.69E-05,"TRPM6, SLC9A3, MT1E, ATP1A1, SLC6A19, MT1H, MT1X, MT1G, MT1F",205,44,6879,6.863747228,0.007897553,0.002639478,0.046759597
KEGG_PATHWAY,hsa01130:Biosynthesis of antibiotics,19,4.241071429,5.17E-05,"TM7SF2, ASS1, SUCLG1, ALDOB, OGDHL, FBP1, PCK2, GLDC, PCK1, CTH, HMGCS2, HAO2, PHGDH, RGN, DAO, PDHA1, HADH, PSAT1, ACAA1",205,212,6879,3.007386102,0.011054658,0.002775196,0.065550155
GOTERM_BP_DIRECT,GO:0035725~sodium ion transmembrane transport,10,2.232142857,7.84E-05,"SLC23A1, SLC4A11, SLC12A3, SCN2A, SLC34A1, SCNN1G, SCN7A, SLC4A9, SCNN1B, SCNN1A",418,73,16792,5.503047781,0.154971696,0.01669754,0.135867292
GOTERM_BP_DIRECT,GO:0045926~negative regulation of growth,6,1.339285714,8.04E-05,"GPC3, MT1E, MT1H, MT1X, MT1G, MT1F",418,19,16792,12.68597331,0.158561057,0.015572191,0.139299537
GOTERM_MF_DIRECT,"GO:0046934~phosphatidylinositol-4,5-bisphosphate 3-kinase activity",9,2.008928571,1.10E-04,"FGFR2, ERBB4, KL, FGF9, ERBB2, PDGFRA, KIT, FGF1, EGF",405,62,16881,6.050537634,0.074188782,0.037809157,0.165318932
KEGG_PATHWAY,hsa04966:Collecting duct acid secretion,7,1.5625,1.11E-04,"ATP6V1C2, CLCNKB, SLC4A1, ATP6V1G3, ATP6V1B1, ATP6V0A4, ATP6V0D2",205,27,6879,8.699728997,0.023598348,0.004764862,0.140770077
GOTERM_MF_DIRECT,GO:0005452~inorganic anion exchanger activity,6,1.339285714,1.14E-04,"SLC4A11, SLC22A12, SLC22A8, SLC22A6, SLC4A1, SLC4A9",405,21,16881,11.90899471,0.076731262,0.026260674,0.171211614
GOTERM_CC_DIRECT,GO:0034706~sodium channel complex,4,0.892857143,1.29E-04,"SCN2A, SCNN1G, SCNN1B, SCNN1A",434,5,18224,33.59262673,0.037710809,0.004793507,0.171563853
GOTERM_BP_DIRECT,GO:0051453~regulation of intracellular pH,7,1.5625,2.34E-04,"SLC26A4, SLC4A11, SLC26A7, SLC9A3, SLC9A2, SLC4A1, SLC4A9",418,36,16792,7.811270601,0.395344187,0.041057973,0.40539211
GOTERM_CC_DIRECT,GO:0005923~bicellular tight junction,11,2.455357143,3.63E-04,"EPCAM, CLDN16, CLDN8, MAGI2, MARVELD2, CGN, ANK3, WNK4, CLDN10, MPP7, EPB41L4B",434,113,18224,4.087598385,0.102884144,0.011990892,0.483805166
GOTERM_CC_DIRECT,GO:0045177~apical part of cell,9,2.008928571,3.99E-04,"PLAT, REEP6, SLC4A9, EPB41L4B, ATP6V0A4, PDZD3, CHL1, DPEP1, CLCN5",434,75,18224,5.038894009,0.112572215,0.011871781,0.532060479
GOTERM_CC_DIRECT,GO:0046658~anchored component of plasma membrane,6,1.339285714,4.63E-04,"PRSS8, GPC3, FOLR1, RHBG, NTNG1, TREH",434,28,18224,8.998025016,0.129303966,0.012508595,0.616597291
GOTERM_BP_DIRECT,GO:1902476~chloride transmembrane transport,10,2.232142857,5.03E-04,"SLC26A4, GABRA2, SLC12A1, SLC12A3, SLC26A7, CLIC5, CLCNKB, ANO5, SLC4A1, CLCN5",418,93,16792,4.319596646,0.660154127,0.079667478,0.867646296
GOTERM_CC_DIRECT,GO:0005903~brush border,8,1.785714286,5.31E-04,"MYO7B, SLC9A3, SCIN, SLC34A1, ATP6V0A4, PDZD3, DCXR, MYH10",434,60,18224,5.598771121,0.146818239,0.013144733,0.706766786
GOTERM_BP_DIRECT,GO:0015698~inorganic anion transport,5,1.116071429,5.38E-04,"SLC26A4, SLC22A12, SLC22A8, SLC22A6, SLC4A9",418,16,16792,12.55382775,0.685220933,0.07924672,0.928956993
GOTERM_BP_DIRECT,GO:0006885~regulation of pH,5,1.116071429,5.38E-04,"SLC26A4, RHCG, ATP6V1B1, ATP6V0A4, ATP12A",418,16,16792,12.55382775,0.685220933,0.07924672,0.928956993
GOTERM_BP_DIRECT,GO:0046854~phosphatidylinositol phosphorylation,10,2.232142857,5.44E-04,"FGFR2, PIK3C2G, ERBB4, KL, FGF9, ERBB2, PDGFRA, KIT, FGF1, EGF",418,94,16792,4.27364349,0.688983063,0.074906557,0.938574625
GOTERM_BP_DIRECT,GO:0010107~potassium ion import,6,1.339285714,5.65E-04,"KCNJ15, ATP1A1, KCNJ10, ATP12A, KCNJ13, KCNJ1",418,28,16792,8.608339029,0.703041929,0.073077454,0.975566111
GOTERM_BP_DIRECT,GO:0071276~cellular response to cadmium ion,5,1.116071429,6.90E-04,"MT1E, MT1H, MT1X, MT1G, MT1F",418,17,16792,11.8153673,0.772861162,0.083495106,1.189638879
GOTERM_MF_DIRECT,GO:0042803~protein homodimerization activity,33,7.366071429,7.43E-04,"FGFR2, CADM4, RAP1GAP, ENPP1, ERBB4, KIT, GPD1L, GSTM3, ANXA9, PVALB, OXCT1, SLC22A6, SLC4A1, CEACAM1, CR2, HOGA1, SLC34A1, EPHX2, C16ORF89, TPD52L1, NR0B2, MECOM, PTPRO, TOX3, SLIT2, PRLR, FBLN5, TFAP2B, PDGFRA, TFAP2A, ABAT, QPRT, HPGD",405,730,16881,1.884231355,0.406971776,0.122456122,1.115261137
KEGG_PATHWAY,hsa00010:Glycolysis / Gluconeogenesis,9,2.008928571,7.57E-04,"G6PC, ALDOB, ADH1C, FBP1, ADH6, ADH1B, PDHA1, PCK2, PCK1",205,67,6879,4.507535493,0.150203715,0.02676182,0.955476656
GOTERM_CC_DIRECT,GO:0005759~mitochondrial matrix,19,4.241071429,8.74E-04,"ALDH6A1, ACADSB, PDP2, ERBB4, SUCLG1, OGDHL, BPHL, PCK2, ACSF2, GLDC, ACSM3, HYKK, HMGCS2, OXCT1, ABAT, ALDH4A1, PDHA1, HADH, BDH1",434,327,18224,2.439831452,0.230093086,0.019913339,1.161251436
KEGG_PATHWAY,"hsa00260:Glycine, serine and threonine metabolism",7,1.5625,9.10E-04,"CHDH, CTH, PHGDH, DAO, PSAT1, PIPOX, GLDC",205,39,6879,6.022889306,0.177789229,0.027578086,1.148086908
GOTERM_BP_DIRECT,GO:0042552~myelination,7,1.5625,9.14E-04,"KLK6, MAL2, ERBB2, SCN2A, NFASC, PLLP, MAL",418,46,16792,6.113168296,0.85968219,0.10336151,1.573167281
KEGG_PATHWAY,hsa00650:Butanoate metabolism,6,1.339285714,0.001034971,"ACSM3, HMGCS2, OXCT1, ABAT, HADH, BDH1",205,27,6879,7.456910569,0.199592286,0.027445588,1.30467443
GOTERM_BP_DIRECT,GO:0015991~ATP hydrolysis coupled proton transport,6,1.339285714,0.001067777,"ATP6V1C2, ATP1A1, ATP6V1B1, ATP6V0A4, ATP12A, ATP6V0D2",418,32,16792,7.532296651,0.899111828,0.113720836,1.834997763
GOTERM_BP_DIRECT,GO:0071294~cellular response to zinc ion,5,1.116071429,0.001080577,"MT1E, MT1H, MT1X, MT1G, MT1F",418,19,16792,10.57164442,0.901849562,0.109580603,1.856801254
GOTERM_BP_DIRECT,GO:0060539~diaphragm development,4,0.892857143,0.00114244,"TCF21, ASS1, STRA6, WT1",418,9,16792,17.8543328,0.9140699,0.110297082,1.962113274
GOTERM_BP_DIRECT,GO:0048015~phosphatidylinositol-mediated signaling,10,2.232142857,0.001294163,"FGFR2, PIK3C2G, ERBB4, KL, FGF9, ERBB2, PDGFRA, KIT, FGF1, EGF",418,106,16792,3.789834793,0.937984352,0.118720445,2.219948652
GOTERM_MF_DIRECT,GO:0015297~antiporter activity,5,1.116071429,0.001400344,"SLC7A8, SLC7A9, SLC7A13, SLC47A2, CLCN5",405,21,16881,9.924162257,0.626610029,0.17883103,2.092296498
GOTERM_BP_DIRECT,GO:0042493~response to drug,18,4.017857143,0.00161566,"ALAD, SORD, ASS1, EMX1, SLC22A12, SLC34A1, ABCB1, ATP1A1, CDH3, PPARGC1A, SFRP1, OXCT1, GATA3, TFAP2B, HSD11B2, ABAT, IGFBP2, HADH",418,304,16792,2.378619995,0.968933571,0.140100989,2.764182958
GOTERM_MF_DIRECT,GO:0005088~Ras guanyl-nucleotide exchange factor activity,10,2.232142857,0.001776456,"FGFR2, ERBB4, KL, FGF9, ERBB2, PDGFRA, SPTBN2, KIT, FGF1, EGF",405,115,16881,3.624476651,0.713483515,0.188058133,2.647252045
KEGG_PATHWAY,hsa01200:Carbon metabolism,11,2.455357143,0.001834005,"ALDH6A1, SUCLG1, OGDHL, ALDOB, HAO2, PHGDH, FBP1, RGN, PDHA1, PSAT1, GLDC",205,113,6879,3.266522771,0.326099654,0.042904938,2.301182638
GOTERM_CC_DIRECT,GO:0005615~extracellular space,50,11.16071429,0.001868339,"ALAD, SORD, ENPP1, FGF9, FAM3B, CRHBP, SELENBP1, KIT, DCN, PRSS8, GPC3, SPX, ALB, PAPPA, SERPINA5, SOSTDC1, PPP1R1A, PROZ, ANGPTL1, EGF, FGF1, DEFB1, DPEP1, F11, MUC1, KLK6, KNG1, PLAT, HYAL1, KLK7, KL, NAPSA, PIGR, SLIT2, ACPP, PLG, PROC, PROM1, C2ORF40, CEL, AFM, SFRP1, TACSTD2, FBLN5, SPTBN2, LIPH, IGFBP2, CMTM4, CTSH, WFDC2",434,1347,18224,1.558677929,0.428308546,0.039152627,2.46679301
GOTERM_BP_DIRECT,GO:0055074~calcium ion homeostasis,5,1.116071429,0.001922784,"KL, TFAP2B, TRPV5, ATP6V1B1, CALB1",418,22,16792,9.130056546,0.983952316,0.158167836,3.281419662
GOTERM_BP_DIRECT,GO:0010842~retina layer formation,5,1.116071429,0.001922784,"PROM1, LHX1, TFAP2B, TFAP2A, CALB1",418,22,16792,9.130056546,0.983952316,0.158167836,3.281419662
GOTERM_MF_DIRECT,GO:0015175~neutral amino acid transmembrane transporter activity,4,0.892857143,0.001945673,"SLC7A8, SLC7A9, SLC7A13, SLC6A19",405,11,16881,15.15690236,0.745674499,0.177651885,2.895973155
KEGG_PATHWAY,"hsa00280:Valine, leucine and isoleucine degradation",7,1.5625,0.002460425,"ALDH6A1, ACADSB, HMGCS2, OXCT1, ABAT, HADH, ACAA1",205,47,6879,4.997716658,0.411185051,0.05158616,3.075927993
GOTERM_CC_DIRECT,GO:0016471~vacuolar proton-transporting V-type ATPase complex,4,0.892857143,0.002497705,"ATP6V1G3, ATP6V1B1, ATP6V0A4, ATP6V0D2",434,12,18224,13.9969278,0.526568533,0.048627761,3.284995193
GOTERM_BP_DIRECT,GO:0006821~chloride transport,6,1.339285714,0.002966234,"GABRA2, SLC26A7, WNK4, CLIC5, ANO5, SLC4A1",418,40,16792,6.025837321,0.998301428,0.22517548,5.019425391
GOTERM_BP_DIRECT,GO:0008152~metabolic process,12,2.678571429,0.003221404,"ACSM3, ENPP6, GSTM3, OXCT1, SUCLG1, HOGA1, HDHD3, EPHX2, MAN1C1, UGT3A1, ACSF2, ACAA1",418,168,16792,2.869446343,0.999019569,0.233900338,5.439944501
GOTERM_MF_DIRECT,GO:0016491~oxidoreductase activity,13,2.901785714,0.003243864,"ASPDH, SORD, ADH1C, ADH1B, ADH6, PIPOX, IYD, HAO2, ALDH4A1, SCD5, HPGD, BDH1, DCXR",405,200,16881,2.709296296,0.898138659,0.248375075,4.784460593
GOTERM_MF_DIRECT,GO:0046983~protein dimerization activity,11,2.455357143,0.003310952,"TCF21, ATP6V1C2, SLC4A11, ERBB2, GATA3, TFAP2B, TFAP2A, ANO5, DAO, CEACAM1, GLDC",405,150,16881,3.056641975,0.902846298,0.228216511,4.881116389
GOTERM_CC_DIRECT,GO:0043235~receptor complex,10,2.232142857,0.003336878,"TM7SF2, CR2, ERBB4, ERBB2, PTH1R, NR3C2, PIGR, BMPR1B, EGF, PLA2R1",434,127,18224,3.306360898,0.631897825,0.060551399,4.366077087
KEGG_PATHWAY,hsa00330:Arginine and proline metabolism,7,1.5625,0.00338307,"NOS1, HOGA1, SAT2, ALDH4A1, PRODH2, DAO, AGMAT",205,50,6879,4.697853659,0.517412601,0.064089801,4.206735626
GOTERM_BP_DIRECT,GO:0006562~proline catabolic process,3,0.669642857,0.003570957,"ALDH4A1, PRODH2, DAO",418,4,16792,30.1291866,0.999538287,0.24758365,6.013159482
GOTERM_BP_DIRECT,GO:0015804~neutral amino acid transport,4,0.892857143,0.003612375,"SLC7A8, SLC7A9, SLC7A13, SLC6A19",418,13,16792,12.36069194,0.999577707,0.242319328,6.080860686
GOTERM_BP_DIRECT,GO:0043069~negative regulation of programmed cell death,4,0.892857143,0.003612375,"ALB, PLCG2, KIT, MECOM",418,13,16792,12.36069194,0.999577707,0.242319328,6.080860686
GOTERM_BP_DIRECT,GO:0060644~mammary gland epithelial cell differentiation,4,0.892857143,0.003612375,"PRLR, ERBB4, IRF6, ELF5",418,13,16792,12.36069194,0.999577707,0.242319328,6.080860686
GOTERM_BP_DIRECT,GO:0001658~branching involved in ureteric bud morphogenesis,6,1.339285714,0.003682707,"TCF21, GPC3, LHX1, NPNT, PBX1, WT1",418,42,16792,5.738892686,0.999637094,0.239021787,6.195719466
KEGG_PATHWAY,hsa04610:Complement and coagulation cascades,8,1.785714286,0.004136821,"PLAT, F11, KNG1, C7, CR2, SERPINA5, PLG, PROC",205,69,6879,3.890562036,0.589861891,0.071580663,5.121511217
GOTERM_BP_DIRECT,GO:0017144~drug metabolic process,5,1.116071429,0.00418359,"FMO4, FMO5, CYP2B6, EPHX2, CYP4F2",418,27,16792,7.439305334,0.999876715,0.259206692,7.009894003
GOTERM_BP_DIRECT,GO:0090383~phagosome acidification,5,1.116071429,0.00418359,"ATP6V1C2, ATP6V1G3, ATP6V1B1, ATP6V0A4, ATP6V0D2",418,27,16792,7.439305334,0.999876715,0.259206692,7.009894003
GOTERM_MF_DIRECT,GO:0050660~flavin adenine dinucleotide binding,7,1.5625,0.004213796,"FMO4, ACOX2, CHDH, FMO5, ACADSB, NOS1, LDHD",405,64,16881,4.558912037,0.948622618,0.256848777,6.172984196
GOTERM_BP_DIRECT,GO:0006094~gluconeogenesis,6,1.339285714,0.004515401,"G6PC, ALDOB, FBP1, PCK2, PPARGC1A, PCK1",418,44,16792,5.478033928,0.999939721,0.269068924,7.545573725
GOTERM_MF_DIRECT,GO:0015106~bicarbonate transmembrane transporter activity,4,0.892857143,0.004997098,"SLC26A4, SLC4A11, SLC26A7, SLC4A1",405,15,16881,11.11506173,0.970452807,0.273967568,7.280509842
GOTERM_MF_DIRECT,GO:0005272~sodium channel activity,4,0.892857143,0.004997098,"SLC4A11, SCNN1G, SCNN1B, SCNN1A",405,15,16881,11.11506173,0.970452807,0.273967568,7.280509842
GOTERM_MF_DIRECT,GO:0008201~heparin binding,11,2.455357143,0.005223416,"FGFR2, F11, KNG1, CEL, SFRP1, FGF9, SERPINA5, LIPH, HRG, FGF1, SLIT2",405,160,16881,2.865601852,0.974819503,0.264207498,7.598225249
GOTERM_CC_DIRECT,GO:0009986~cell surface,24,5.357142857,0.00552785,"PLAT, FGFR2, ENPP1, CLSTN2, SLC9A3, SLC34A1, ABCB1, L1CAM, PLG, SLIT2, PROM1, EPCAM, CEL, PROM2, ANXA9, TSPAN33, HSPA2, SFRP1, PRLR, ANK3, FOLR1, SORT1, PLA2R1, CEACAM1",434,542,18224,1.859370483,0.809368397,0.092892989,7.13617309
GOTERM_BP_DIRECT,GO:0015695~organic cation transport,4,0.892857143,0.00553906,"SLC22A13, RHCG, SLC7A8, RHBG",418,15,16792,10.71259968,0.99999338,0.311107061,9.179916815
GOTERM_BP_DIRECT,GO:0097070~ductus arteriosus closure,3,0.669642857,0.005853928,"TFAP2B, STRA6, HPGD",418,5,16792,24.10334928,0.999996646,0.317490762,9.677123927
GOTERM_BP_DIRECT,GO:0071356~cellular response to tumor necrosis factor,9,2.008928571,0.006123862,"HYAL1, ASS1, SFRP1, CRHBP, GATA3, NPNT, PCK2, PPARGC1A, PCK1",418,110,16792,3.286820357,0.999998128,0.321514902,10.10133348
GOTERM_BP_DIRECT,GO:0007565~female pregnancy,8,1.785714286,0.006655031,"MUC1, PAPPA, CRHBP, CLIC5, TFCP2L1, HSD11B2, IGFBP2, HPGD",418,89,16792,3.610988657,0.999999406,0.336086272,10.93060607
GOTERM_MF_DIRECT,GO:0017080~sodium channel regulator activity,5,1.116071429,0.006841547,"GPD1L, PRSS8, FXYD4, NOS1, NEDD4L",405,32,16881,6.512731481,0.991982556,0.310122476,9.840383553
KEGG_PATHWAY,hsa00071:Fatty acid degradation,6,1.339285714,0.007613061,"ACADSB, ADH1C, ADH6, ADH1B, HADH, ACAA1",205,42,6879,4.793728223,0.806614654,0.118728948,9.237178332
GOTERM_MF_DIRECT,GO:0005509~calcium ion binding,29,6.473214286,0.007768334,"CLSTN2, ENPP1, NELL1, NPNT, FSTL4, UMOD, CDH3, KCNIP1, CALB1, NECAB1, EFHD1, CDH9, ANXA9, PVALB, DNER, PROZ, AIF1L, PLCD4, RGN, EGF, CPNE6, MAN1C1, SLIT2, ANXA3, PROC, CDH16, FBLN5, VSNL1, SCIN",405,717,16881,1.685861873,0.99584092,0.324028514,11.1015964
GOTERM_BP_DIRECT,GO:0003091~renal water homeostasis,5,1.116071429,0.007777458,"PRKAR2B, CYP4A11, TFAP2B, CYP4F2, AQP2",418,32,16792,6.276913876,0.999999948,0.372274361,12.65931316
GOTERM_MF_DIRECT,"GO:0004024~alcohol dehydrogenase activity, zinc-dependent",3,0.669642857,0.008040563,"ADH1C, ADH6, ADH1B",405,6,16881,20.84074074,0.996570575,0.315014438,11.46891498
GOTERM_BP_DIRECT,GO:0055085~transmembrane transport,14,3.125,0.008160619,"ABCA8, SLC5A2, SLC16A5, SLC12A1, SLC22A13, SLC44A4, SLC15A2, SLC22A7, MFSD4A, SLC13A2, MAL, ABCB1, SLC13A3, SLC47A2",418,244,16792,2.304965095,0.999999977,0.378412884,13.24216497
GOTERM_BP_DIRECT,GO:0007568~aging,11,2.455357143,0.008276365,"NAPEPLD, ASS1, KL, PTH1R, RGN, ABAT, DCN, IGFBP2, PPARGC1A, NPY5R, PCK1",418,165,16792,2.67814992,0.999999982,0.374722933,13.41751129
GOTERM_CC_DIRECT,GO:0016328~lateral plasma membrane,6,1.339285714,0.008328751,"EPCAM, TACSTD2, ANK3, ATP6V1B1, PTPRO, CEACAM1",434,53,18224,4.753673594,0.917974486,0.129710325,10.56932501
GOTERM_BP_DIRECT,GO:0042472~inner ear morphogenesis,6,1.339285714,0.009198706,"FGFR2, FGF9, GATA3, TFAP2A, ATP6V1B1, FOXI1",418,52,16792,4.635259477,0.999999998,0.398749752,14.80290575
GOTERM_BP_DIRECT,GO:0006631~fatty acid metabolic process,6,1.339285714,0.009198706,"PRKAR2B, CYP4A11, ACADSB, ACOT11, HADH, ACSF2",418,52,16792,4.635259477,0.999999998,0.398749752,14.80290575
GOTERM_BP_DIRECT,GO:0019373~epoxygenase P450 pathway,4,0.892857143,0.009401339,"CYP4A11, CYP2B6, EPHX2, CYP4F2",418,18,16792,8.927166401,0.999999998,0.397702578,15.10445806
GOTERM_MF_DIRECT,GO:0050661~NADP binding,5,1.116071429,0.009418512,"TM7SF2, FMO4, FMO5, ASPDH, NOS1",405,35,16881,5.954497354,0.998709328,0.340179204,13.30654379
KEGG_PATHWAY,hsa04961:Endocrine and other factor-regulated calcium reabsorption,6,1.339285714,0.010180602,"KL, PTH1R, TRPV5, ATP1A1, KLK1, CALB1",205,45,6879,4.474146341,0.889202105,0.145420933,12.17070265
GOTERM_BP_DIRECT,GO:0030501~positive regulation of bone mineralization,5,1.116071429,0.0106846,"KL, NELL1, TFAP2A, GPM6B, BMPR1B",418,35,16792,5.738892686,1,0.430227855,16.99093465
GOTERM_BP_DIRECT,GO:0033572~transferrin transport,5,1.116071429,0.0106846,"ATP6V1C2, ATP6V1G3, ATP6V1B1, ATP6V0A4, ATP6V0D2",418,35,16792,5.738892686,1,0.430227855,16.99093465
GOTERM_MF_DIRECT,GO:0003707~steroid hormone receptor activity,6,1.339285714,0.010763843,"NR1I3, THRB, NR3C2, ESRRG, NR0B2, PAQR5",405,56,16881,4.465873016,0.999503537,0.360794618,15.06625937
GOTERM_BP_DIRECT,GO:0010765~positive regulation of sodium ion transport,4,0.892857143,0.010961482,"GPD1L, PRSS8, ANK3, CNTN1",418,19,16792,8.457315538,1,0.430749242,17.39275426
GOTERM_CC_DIRECT,GO:0005604~basement membrane,7,1.5625,0.011240402,"FRAS1, LAD1, FREM2, FGF9, FREM1, NPNT, NTN4",434,79,18224,3.720702327,0.965949536,0.162965579,14.01345716
KEGG_PATHWAY,hsa00020:Citrate cycle (TCA cycle),5,1.116071429,0.011245391,"SUCLG1, OGDHL, PDHA1, PCK2, PCK1",205,30,6879,5.592682927,0.912091266,0.149641348,13.36144386
GOTERM_CC_DIRECT,GO:0005902~microvillus,6,1.339285714,0.011254304,"PROM2, MYO7B, RAPGEF3, ATP6V1B1, DCXR, KIF13B",434,57,18224,4.420082464,0.966092389,0.155664869,14.02960373
GOTERM_MF_DIRECT,GO:0005242~inward rectifier potassium channel activity,4,0.892857143,0.011461155,"KCNJ15, KCNJ10, KCNJ13, KCNJ1",405,20,16881,8.336296296,0.999697588,0.362503614,15.96517697
GOTERM_MF_DIRECT,GO:0030506~ankyrin binding,4,0.892857143,0.011461155,"RHCG, RHBG, ATP1A1, SLC4A1",405,20,16881,8.336296296,0.999697588,0.362503614,15.96517697
GOTERM_BP_DIRECT,GO:0072112~glomerular visceral epithelial cell differentiation,3,0.669642857,0.01189432,"PROM1, PTPRO, WT1",418,7,16792,17.21667806,1,0.449785116,18.73307023
GOTERM_MF_DIRECT,GO:0004714~transmembrane receptor protein tyrosine kinase activity,5,1.116071429,0.012555691,"FGFR2, ERBB4, ERBB2, PDGFRA, KIT",405,38,16881,5.484405458,0.999861208,0.373434315,17.35826678
GOTERM_MF_DIRECT,GO:0051287~NAD binding,5,1.116071429,0.012555691,"GPD1L, SORD, PHGDH, HSD11B2, HPGD",405,38,16881,5.484405458,0.999861208,0.373434315,17.35826678
GOTERM_MF_DIRECT,GO:0015347~sodium-independent organic anion transmembrane transporter activity,4,0.892857143,0.013137957,"SLC22A12, SLC22A7, SLC22A8, SLC22A6",405,21,16881,7.939329806,0.999908319,0.371776673,18.09053833
GOTERM_BP_DIRECT,GO:0043401~steroid hormone mediated signaling pathway,6,1.339285714,0.013406931,"NR1I3, THRB, NR3C2, ESRRG, NR0B2, PAQR5",418,57,16792,4.228657769,1,0.482436101,20.86294667
KEGG_PATHWAY,hsa05120:Epithelial cell signaling in Helicobacter pylori infection,7,1.5625,0.014039,"ATP6V1C2, PLCG2, MAPK10, ATP6V1G3, ATP6V1B1, ATP6V0A4, ATP6V0D2",205,67,6879,3.505860939,0.952154248,0.173029131,16.41518072
GOTERM_CC_DIRECT,GO:0036057~slit diaphragm,3,0.669642857,0.014343507,"MAGI2, NPHS2, NPHS1",434,8,18224,15.74654378,0.986696971,0.185925201,17.54868708
GOTERM_MF_DIRECT,GO:0015280~ligand-gated sodium channel activity,3,0.669642857,0.014540405,"SCNN1G, SCNN1B, SCNN1A",405,8,16881,15.63055556,0.999966264,0.387576265,19.8294975
KEGG_PATHWAY,hsa00982:Drug metabolism - cytochrome P450,7,1.5625,0.015028835,"FMO4, FMO5, GSTM3, CYP2B6, ADH1C, ADH6, ADH1B",205,68,6879,3.454304161,0.961447186,0.174291361,17.47317443
GOTERM_BP_DIRECT,GO:0050891~multicellular organismal water homeostasis,3,0.669642857,0.015600464,"SCNN1G, SCNN1B, SCNN1A",418,8,16792,15.0645933,1,0.527719608,23.85835302
GOTERM_BP_DIRECT,GO:0033689~negative regulation of osteoblast proliferation,3,0.669642857,0.015600464,"SFRP1, PLXNB1, NELL1",418,8,16792,15.0645933,1,0.527719608,23.85835302
GOTERM_BP_DIRECT,GO:0001766~membrane raft polarization,3,0.669642857,0.015600464,"MAL2, PLLP, MAL",418,8,16792,15.0645933,1,0.527719608,23.85835302
GOTERM_BP_DIRECT,GO:0050679~positive regulation of epithelial cell proliferation,6,1.339285714,0.016470103,"FGFR2, HYAL1, SFRP1, FGF9, ERBB2, FGF1",418,60,16792,4.01722488,1,0.539353812,25.01605624
GOTERM_CC_DIRECT,GO:0031090~organelle membrane,7,1.5625,0.017458815,"TM7SF2, FMO4, FMO5, CYP4A11, RDH10, CYP2B6, CYP4F2",434,87,18224,3.37856878,0.994837283,0.212881858,20.96214709
GOTERM_BP_DIRECT,GO:0007411~axon guidance,10,2.232142857,0.017936588,"ANK3, GATA3, NFASC, SPTBN2, NTN4, L1CAM, PTPRO, SLIT2, CHL1, MYH10",418,159,16792,2.526556529,1,0.562551338,26.93082249
GOTERM_BP_DIRECT,GO:0007605~sensory perception of sound,9,2.008928571,0.01799701,"SLC26A4, THRB, MARVELD2, CLIC5, DCDC2, TFAP2A, ATP6V1B1, ATP6V0A4, SLC52A3",418,133,16792,2.718422851,1,0.556174168,27.00871705
GOTERM_CC_DIRECT,GO:0031225~anchored component of membrane,8,1.785714286,0.018283644,"ENPP6, GPC3, GP2, CNTN1, UMOD, CNTN3, DPEP1, XPNPEP2",434,113,18224,2.972798825,0.995983738,0.213283336,21.84376472
KEGG_PATHWAY,hsa05110:Vibrio cholerae infection,6,1.339285714,0.018344716,"ATP6V1C2, PLCG2, ATP6V1G3, ATP6V1B1, ATP6V0A4, ATP6V0D2",205,52,6879,3.871857411,0.981328173,0.198405326,20.92816389
GOTERM_MF_DIRECT,"GO:0008553~hydrogen-exporting ATPase activity, phosphorylative mechanism",3,0.669642857,0.018401518,"ATP6V1C2, ATP6V1G3, ATP6V0D2",405,9,16881,13.89382716,0.999997864,0.447603731,24.44064007
GOTERM_BP_DIRECT,GO:0043252~sodium-independent organic anion transport,4,0.892857143,0.018623183,"ALB, SLC22A12, SLC22A8, SLC22A6",418,23,16792,6.986478053,1,0.561192034,27.81137544
GOTERM_BP_DIRECT,GO:0009880~embryonic pattern specification,4,0.892857143,0.018623183,"FGFR2, ERBB4, LHX1, SIM2",418,23,16792,6.986478053,1,0.561192034,27.81137544
GOTERM_CC_DIRECT,GO:0043025~neuronal cell body,15,3.348214286,0.018767781,"DDC, GABRA2, RAP1GAP, CALB1, PPARGC1A, ANXA3, PRKAR2B, CYP17A1, PVALB, DNER, PDE1A, SPTBN2, SORT1, BMPR1B, MYH10",434,315,18224,1.999561115,0.996534482,0.210248719,22.35698918
GOTERM_BP_DIRECT,GO:0009636~response to toxic substance,7,1.5625,0.019091357,"TRPM6, SLC23A1, SLC22A8, SLC7A8, EPHX2, BPHL, PDZD3",418,85,16792,3.308302843,1,0.562950704,28.40606024
GOTERM_MF_DIRECT,GO:0016303~1-phosphatidylinositol-3-kinase activity,5,1.116071429,0.019130051,"FGFR2, PIK3C2G, KL, FGF9, FGF1",405,43,16881,4.846683893,0.999998733,0.445882954,25.2824263
KEGG_PATHWAY,hsa00350:Tyrosine metabolism,5,1.116071429,0.019159658,"DDC, ADH1C, ADH6, ADH1B, HPD",205,35,6879,4.793728223,0.984381518,0.196606416,21.75664387
GOTERM_BP_DIRECT,GO:0043583~ear development,3,0.669642857,0.019731328,"RDH10, GATA3, STRA6",418,9,16792,13.3907496,1,0.567837918,29.2115019
GOTERM_BP_DIRECT,GO:0032835~glomerulus development,3,0.669642857,0.019731328,"TCF21, PTPRO, WT1",418,9,16792,13.3907496,1,0.567837918,29.2115019
GOTERM_BP_DIRECT,GO:0034765~regulation of ion transmembrane transport,8,1.785714286,0.020728568,"KCNJ15, CLIC5, SCN2A, KCNJ10, NEDD4L, SCN7A, KCNJ13, KCNJ1",418,111,16792,2.895297211,1,0.578883377,30.44958705
GOTERM_BP_DIRECT,GO:0045880~positive regulation of smoothened signaling pathway,4,0.892857143,0.020899941,"GPC3, SFRP1, FGF9, DCDC2",418,24,16792,6.695374801,1,0.574979318,30.66028401
GOTERM_MF_DIRECT,GO:0019911~structural constituent of myelin sheath,3,0.669642857,0.022641775,"MAL2, PLLP, MAL",405,10,16881,12.50444444,0.999999898,0.488720467,29.21864315
GOTERM_MF_DIRECT,GO:0004716~receptor signaling protein tyrosine kinase activity,3,0.669642857,0.022641775,"ERBB4, ERBB2, KIT",405,10,16881,12.50444444,0.999999898,0.488720467,29.21864315
GOTERM_BP_DIRECT,GO:0015701~bicarbonate transport,5,1.116071429,0.02328913,"SLC26A4, SLC4A11, SLC26A7, SLC4A1, SLC4A9",418,44,16792,4.565028273,1,0.608163779,33.53575933
GOTERM_BP_DIRECT,GO:0070372~regulation of ERK1 and ERK2 cascade,4,0.892857143,0.023322355,"FGFR2, PKHD1, ERBB2, CEACAM1",418,25,16792,6.427559809,1,0.601960684,33.57494253
GOTERM_CC_DIRECT,GO:0005782~peroxisomal matrix,5,1.116071429,0.023391487,"ACOX2, HAO2, DAO, PIPOX, ACAA1",434,46,18224,4.564215588,0.999155827,0.246545121,27.10380842
GOTERM_BP_DIRECT,GO:0006000~fructose metabolic process,3,0.669642857,0.024263637,"PFKFB2, ALDOB, FBP1",418,10,16792,12.05167464,1,0.610044275,34.67603442
GOTERM_BP_DIRECT,GO:0010944~negative regulation of transcription by competitive promoter binding,3,0.669642857,0.024263637,"MUC1, TFAP2A, DACH1",418,10,16792,12.05167464,1,0.610044275,34.67603442
GOTERM_CC_DIRECT,GO:0045121~membrane raft,11,2.455357143,0.025637472,"PRKAR2B, PROM2, NOS1, ANK2, MAL2, NPHS2, SLC34A1, CNTN1, GPM6B, PLLP, MAL",434,206,18224,2.242226299,0.999575916,0.258200399,29.31137627
GOTERM_BP_DIRECT,GO:0046487~glyoxylate metabolic process,4,0.892857143,0.025890399,"HOGA1, DAO, PDHA1, GLDC",418,26,16792,6.18034597,1,0.627698571,36.53854432
GOTERM_MF_DIRECT,GO:0004177~aminopeptidase activity,4,0.892857143,0.026009142,"PEPD, DPP6, CTSH, XPNPEP2",405,27,16881,6.175034294,0.999999991,0.523389907,32.81045012
GOTERM_MF_DIRECT,GO:0004435~phosphatidylinositol phospholipase C activity,4,0.892857143,0.026009142,"PLCL1, CASR, PLCG2, PLCD4",405,27,16881,6.175034294,0.999999991,0.523389907,32.81045012
GOTERM_MF_DIRECT,GO:0005496~steroid binding,4,0.892857143,0.026009142,"NR3C2, ESRRG, HSD11B2, PAQR5",405,27,16881,6.175034294,0.999999991,0.523389907,32.81045012
GOTERM_CC_DIRECT,GO:0005796~Golgi lumen,7,1.5625,0.026893401,"MUC1, GPC3, PROZ, DCN, MUC15, DEFB1, PROC",434,96,18224,3.061827957,0.99971162,0.260586134,30.51869516
GOTERM_BP_DIRECT,GO:0044267~cellular protein metabolic process,8,1.785714286,0.027832925,"ZDHHC2, PAPPA, SLC34A1, PAPPA2, NAPSA, IGFBP2, CTSH, PLG",418,118,16792,2.723542292,1,0.648275798,38.69702538
GOTERM_BP_DIRECT,GO:0046839~phospholipid dephosphorylation,3,0.669642857,0.029175003,"PLPP4, EPHX2, PLPPR1",418,11,16792,10.95606786,1,0.659543714,40.14768911
KEGG_PATHWAY,hsa04964:Proximal tubule bicarbonate reclamation,4,0.892857143,0.029403706,"SLC9A3, ATP1A1, PCK2, PCK1",205,23,6879,5.835843054,0.9983658,0.274453487,31.51110669
GOTERM_BP_DIRECT,GO:0030855~epithelial cell differentiation,6,1.339285714,0.029917201,"FGFR2, MUC1, TCF21, RHCG, EHF, WT1",418,70,16792,3.443335612,1,0.662732075,40.9359833
GOTERM_BP_DIRECT,GO:0007417~central nervous system development,8,1.785714286,0.030132434,"KLK6, RPS6KA6, PCP4, DNER, ARNT2, CASZ1, MAL, SH3GL2",418,120,16792,2.67814992,1,0.659339868,41.16274816
GOTERM_BP_DIRECT,GO:0010628~positive regulation of gene expression,13,2.901785714,0.031312533,"STAP1, FGF9, ERBB2, EPHX2, NR0B2, EPB41L4B, KIT, CDH3, ANK2, ANK3, CNTN1, TFAP2A, CTSH",418,262,16792,1.993279521,1,0.667681718,42.39156177
GOTERM_CC_DIRECT,GO:0033270~paranode region of axon,3,0.669642857,0.031757359,"ANK3, NFASC, KIF13B",434,12,18224,10.49769585,0.999935542,0.291513905,35.01666554
GOTERM_MF_DIRECT,GO:0015643~toxic substance binding,3,0.669642857,0.032179403,"ASS1, ALB, EPHX2",405,12,16881,10.42037037,1,0.587033442,38.9542963
GOTERM_MF_DIRECT,GO:0008081~phosphoric diester hydrolase activity,3,0.669642857,0.032179403,"ENPP6, PLCXD3, PLCG2",405,12,16881,10.42037037,1,0.587033442,38.9542963
GOTERM_BP_DIRECT,GO:0036092~phosphatidylinositol-3-phosphate biosynthetic process,5,1.116071429,0.033030657,"FGFR2, PIK3C2G, KL, FGF9, FGF1",418,49,16792,4.099209062,1,0.681672425,44.13744465
GOTERM_BP_DIRECT,GO:0015992~proton transport,5,1.116071429,0.033030657,"SLC2A12, SLC4A11, SLC15A2, ATP6V1B1, ATP6V0A4",418,49,16792,4.099209062,1,0.681672425,44.13744465
GOTERM_CC_DIRECT,GO:0009925~basal plasma membrane,4,0.892857143,0.033651841,"SLC23A1, TACSTD2, ANK3, CEACAM1",434,30,18224,5.598771121,0.999964112,0.297376725,36.6945002
KEGG_PATHWAY,hsa00072:Synthesis and degradation of ketone bodies,3,0.669642857,0.033668688,"HMGCS2, OXCT1, BDH1",205,10,6879,10.06682927,0.999365983,0.29576257,35.2314316
GOTERM_BP_DIRECT,GO:0030195~negative regulation of blood coagulation,3,0.669642857,0.0344439,"KNG1, TSPAN8, PROC",418,12,16792,10.0430622,1,0.691444637,45.53602263
GOTERM_BP_DIRECT,GO:0006069~ethanol oxidation,3,0.669642857,0.0344439,"ADH1C, ADH6, ADH1B",418,12,16792,10.0430622,1,0.691444637,45.53602263
GOTERM_BP_DIRECT,GO:0097067~cellular response to thyroid hormone stimulus,3,0.669642857,0.0344439,"KIT, CTSH, PPARGC1A",418,12,16792,10.0430622,1,0.691444637,45.53602263
GOTERM_MF_DIRECT,GO:0017147~Wnt-protein binding,4,0.892857143,0.037280374,"SFRP1, WLS, EGF, PTPRO",405,31,16881,5.378255675,1,0.628135824,43.63302289
GOTERM_MF_DIRECT,GO:0003824~catalytic activity,10,2.232142857,0.037399048,"ACSM3, FHIT, CEL, ALAD, PFKFB2, EPHX2, HPGD, SUGCT, ACSF2, PBLD",405,188,16881,2.217100079,1,0.615953724,43.73777693
GOTERM_MF_DIRECT,GO:0004629~phospholipase C activity,3,0.669642857,0.037438464,"PLCL1, PLCG2, PLCD4",405,13,16881,9.618803419,1,0.603462683,43.77252916
GOTERM_BP_DIRECT,GO:0098656~anion transmembrane transport,4,0.892857143,0.037608324,"SLC22A7, SLC22A8, SLC22A6, SLC4A9",418,30,16792,5.356299841,1,0.718097409,48.54888197
GOTERM_BP_DIRECT,GO:0010468~regulation of gene expression,7,1.5625,0.038365459,"G6PC, LHX1, NELL1, PLCG2, PHGDH, SORT1, HRG",418,100,16792,2.812057416,1,0.719900766,49.24609633
GOTERM_CC_DIRECT,GO:0030424~axon,11,2.455357143,0.039626202,"DDC, CYP17A1, GABRA2, RAP1GAP, CPNE6, SCN2A, CALB1, PTPRO, ANXA3, KIF13B, MYH10",434,222,18224,2.080624403,0.999994381,0.331674011,41.72680067
GOTERM_BP_DIRECT,GO:0071320~cellular response to cAMP,5,1.116071429,0.039858342,"ASS1, CRHBP, RAPGEF3, WT1, PCK1",418,52,16792,3.862716231,1,0.728394189,50.59482785
GOTERM_MF_DIRECT,GO:0015078~hydrogen ion transmembrane transporter activity,4,0.892857143,0.040429218,"ATP6V1C2, ATP6V1B1, ATP6V0A4, ATP6V0D2",405,32,16881,5.210185185,1,0.619806463,46.35174363
GOTERM_BP_DIRECT,GO:0030324~lung development,6,1.339285714,0.040561252,"FGFR2, SLC23A1, GPC3, STRA6, FGF1, SIM2",418,76,16792,3.171493327,1,0.729466379,51.21810312
GOTERM_MF_DIRECT,GO:0016787~hydrolase activity,10,2.232142857,0.0406593,"FHIT, CEL, INPP5J, HRASLS2, HDHD3, EPHX2, MPPED2, BPHL, PROC, XPNPEP2",405,191,16881,2.182276517,1,0.60988629,46.54551696
GOTERM_BP_DIRECT,GO:0048701~embryonic cranial skeleton morphogenesis,4,0.892857143,0.04089435,"FGFR2, PDGFRA, TFAP2A, GRHL2",418,31,16792,5.183515975,1,0.727254563,51.5108694
GOTERM_CC_DIRECT,GO:0031093~platelet alpha granule lumen,5,1.116071429,0.041472117,"KNG1, ALB, HRG, EGF, PLG",434,55,18224,3.817343946,0.999996839,0.335377781,43.20513754
GOTERM_MF_DIRECT,GO:0031404~chloride ion binding,3,0.669642857,0.043000001,"CLCNKB, SLC22A6, CLCN5",405,14,16881,8.931746032,1,0.619233157,48.48004725
GOTERM_MF_DIRECT,GO:0043565~sequence-specific DNA binding,20,4.464285714,0.044255758,"THRB, EMX1, TFCP2L1, ELF5, NR3C2, ESRRG, EHF, PRDM16, PPARGC1A, GRHL2, WT1, NR1I3, HOXD8, LHX1, HOXA7, TFAP2B, TFAP2A, HOXB9, PBX1, FOXI1",405,518,16881,1.609323609,1,0.61874247,49.49075767
GOTERM_BP_DIRECT,GO:0070830~bicellular tight junction assembly,4,0.892857143,0.044320235,"MARVELD2, PTPN13, MPP7, GRHL2",418,32,16792,5.0215311,1,0.751026633,54.42739175
GOTERM_BP_DIRECT,GO:0006694~steroid biosynthetic process,4,0.892857143,0.044320235,"CYP17A1, PRLR, TFCP2L1, PBX1",418,32,16792,5.0215311,1,0.751026633,54.42739175
GOTERM_BP_DIRECT,GO:0008286~insulin receptor signaling pathway,6,1.339285714,0.044558434,"ATP6V1C2, KL, ATP6V1G3, ATP6V1B1, ATP6V0A4, ATP6V0D2",418,78,16792,3.090172985,1,0.748009556,54.62390244
GOTERM_BP_DIRECT,GO:0014912~negative regulation of smooth muscle cell migration,3,0.669642857,0.045972305,"SEMA6D, PPARGC1A, SLIT2",418,14,16792,8.608339029,1,0.754235108,55.77398731
GOTERM_BP_DIRECT,GO:1902043~positive regulation of extrinsic apoptotic signaling pathway via death domain receptors,3,0.669642857,0.045972305,"SFRP1, MAL, BMPR1B",418,14,16792,8.608339029,1,0.754235108,55.77398731
KEGG_PATHWAY,hsa04974:Protein digestion and absorption,7,1.5625,0.04597402,"SLC9A3, SLC7A8, SLC7A9, ATP1A1, SLC6A19, KCNJ13, XPNPEP2",205,88,6879,2.669235033,0.999959687,0.368683087,44.94755953
GOTERM_MF_DIRECT,GO:0004613~phosphoenolpyruvate carboxykinase (GTP) activity,2,0.446428571,0.047293095,"PCK2, PCK1",405,2,16881,41.68148148,1,0.632757572,51.85936469
GOTERM_MF_DIRECT,GO:0030170~pyridoxal phosphate binding,5,1.116071429,0.047321785,"DDC, CTH, ALB, ABAT, GLDC",405,57,16881,3.656270305,1,0.622323399,51.88123494
GOTERM_BP_DIRECT,GO:0010634~positive regulation of epithelial cell migration,4,0.892857143,0.047884246,"HYAL1, EPB41L5, RAB25, CTSH",418,33,16792,4.869363491,1,0.763818898,57.28558223
GOTERM_CC_DIRECT,GO:0033268~node of Ranvier,3,0.669642857,0.048221364,"ANK3, SCN2A, NFASC",434,15,18224,8.398156682,0.999999618,0.369848019,48.32011817
GOTERM_BP_DIRECT,GO:0001503~ossification,6,1.339285714,0.04878318,"CASR, SLC34A1, SORT1, GPM6B, ATP6V1B1, ATP6V0A4",418,80,16792,3.01291866,1,0.765678254,57.97933525
GOTERM_MF_DIRECT,GO:0008392~arachidonic acid epoxygenase activity,3,0.669642857,0.048846601,"CYP4A11, CYP2B6, CYP4F2",405,15,16881,8.336296296,1,0.623918607,53.03034939
GOTERM_BP_DIRECT,GO:0072156~distal tubule morphogenesis,2,0.446428571,0.04905126,"WNK4, KLHL3",418,2,16792,40.1722488,1,0.76302049,58.18416188
GOTERM_BP_DIRECT,GO:0090260~negative regulation of retinal ganglion cell axon guidance,2,0.446428571,0.04905126,"PTPRO, SLIT2",418,2,16792,40.1722488,1,0.76302049,58.18416188
GOTERM_BP_DIRECT,GO:0009448~gamma-aminobutyric acid metabolic process,2,0.446428571,0.04905126,"PHGDH, ABAT",418,2,16792,40.1722488,1,0.76302049,58.18416188
GOTERM_BP_DIRECT,GO:0032305~positive regulation of icosanoid secretion,2,0.446428571,0.04905126,"CYP4A11, CYP4F2",418,2,16792,40.1722488,1,0.76302049,58.18416188
GOTERM_BP_DIRECT,GO:0006116~NADH oxidation,2,0.446428571,0.04905126,"ALDOB, PCK2",418,2,16792,40.1722488,1,0.76302049,58.18416188