1. Up-regulated CDC20 ACSL4 NCAPG RACGAP1 SQLE TOP2A ECM1 MUC13 GPC3 CAP2 CDKN3 PLVAP PTTG1 NUSAP1 SPINK1 MELK REG3A CCNB2 MDK RFC4 ASPM MCM6 MCM2 AURKA TXNRD1 PRC1 2. Down-regulated VIPR1 ACSM3 MT1M AQP9 MT1X ACSM5 GBA3 ENO3 CRHBP FAM134B TDO2 C8orf4 SDS ACSL1 UPB1 CYP39A1 MT1F MT1G CYP2E1 SKAP1 CETP SLC22A1 PLAC8 C6 C7 C9 RDH16 APOF CD14 PCK1 HAO2 EGR1 AKR1B10 SLC10A1 CYP4F2 IGF1 CYP2C9 CYP26A1 MARCO CYP2C8 BHMT FXYD1 CYP1A2 ID1 PEMT CPEB3 HAMP PTH1R CSAD PHGDH FOS F9 RDH5 CHST4 DNASE1L3 SAA4 AKR1D1 AFM SPP2 BCHE GCGR BBOX1 GNMT FOSB KLKB1 FCN2 FCN3 STEAP3 FAM13A OGDHL AKR7A3 ACAA1 PHLDA1 PAMR1 ZGPAT ANXA10 KMO PLA2G16 MASP2 IGFALS SLC27A5 LY6E NNMT PROZ GLYAT SOCS2 SLCO1B3 SRD5A2 DNAJC12 RCL1 RCAN1 CXCL12 NAT2 SHBG TAT LECT2 PZP RND3 CYR61 FTCD GHR CLEC1B HGFAC MBL2 CYP4A11 DCN CDHR2 FBP1 GLS2 PON1 LCAT CYP3A4 APOC4 GSTZ1 CTH ALDH8A1