Table S3:GO enrichment results of differentially expressed genes in LCC and RCC Category Term Count % PValue Genes List Total Pop Hits Pop Total Fold Enrichment Bonferroni Benjamini FDR GOTERM_BP_DIRECT GO:0008306~associative learning 7 1.983002833 3.30E-06 NEUROD2, CHRNA7, CHRFAM7A, NPTX2, DRD2, TAC1, DRD5 303 24 16792 16.16391639 0.005159278 0.005172625 0.005159429 GOTERM_BP_DIRECT GO:0050482~arachidonic acid secretion 6 1.699716714 5.84E-05 PLA2G2D, PLA2G12B, PLA2G3, PLA2G4A, NMUR2, DRD2 303 24 16792 13.85478548 0.0875464 0.045807684 0.045690827 GOTERM_BP_DIRECT GO:0009952~anterior/posterior pattern specification 9 2.549575071 9.41E-05 HOXC5, HOXC4, HOXB2, HOXD3, HOXC9, HOXC8, HOXC11, HOXC10, HOXC6 303 80 16792 6.234653465 0.137198468 0.049187882 0.049062402 GOTERM_BP_DIRECT GO:0006811~ion transport 10 2.83286119 4.85E-04 SLCO1B1, GABRP, CLDN10, SLC15A1, CHRNA7, CHRFAM7A, HTR3A, SLC17A8, SLC26A9, SLC1A7 303 127 16792 4.363711962 0.532622322 0.169566964 0.169134396 GOTERM_BP_DIRECT GO:0006959~humoral immune response 7 1.983002833 5.41E-04 BST2, IFNG, AIRE, POU2AF1, PAX5, PDCD1, MS4A1 303 57 16792 6.805859533 0.571756843 0.169566964 0.169134396 GOTERM_BP_DIRECT GO:0007586~digestion 7 1.983002833 9.25E-04 PYY, SLC15A1, MEP1B, UGT1A1, TFF2, TFF1, CTSE 303 63 16792 6.157682435 0.765808987 0.214089872 0.213543724 GOTERM_BP_DIRECT GO:0010628~positive regulation of gene expression 14 3.966005666 9.56E-04 TFAP2A, ZNF683, FOXD1, CITED1, OSR1, ARX, SLC6A4, WNT11, IFNG, AGR2, HOXD3, SLC26A9, AMH, NKX3-1 303 262 16792 2.961328194 0.776723803 0.214089872 0.213543724 GOTERM_BP_DIRECT GO:0031424~keratinization 6 1.699716714 0.00165521 SPRR3, KRT16, KRT2, ABCA12, SPRR1A, SPRR1B 303 48 16792 6.927392739 0.925541924 0.304748665 0.303971245 GOTERM_BP_DIRECT GO:0006730~one-carbon metabolic process 5 1.416430595 0.00194355 ALDH1L1, CA5A, CA4, CA9, CA8 303 30 16792 9.236523652 0.952662475 0.304748665 0.303971245 GOTERM_BP_DIRECT GO:0048706~embryonic skeletal system development 5 1.416430595 0.00194355 DLX1, WNT11, HOXD1, HOXC5, HOXC6 303 30 16792 9.236523652 0.952662475 0.304748665 0.303971245 GOTERM_BP_DIRECT GO:0006816~calcium ion transport 7 1.983002833 0.002451805 SLN, TRPV6, CCL5, CHRNA7, NMUR2, CHRFAM7A, RAMP1 303 76 16792 5.10439465 0.978702178 0.349493624 0.348602059 GOTERM_BP_DIRECT GO:0042493~response to drug 14 3.966005666 0.003560011 EMX1, ABCG8, UGT1A1, GAD1, ABCA3, PAX4, SLC6A4, SLC22A12, FABP3, IFNG, CYP1A1, CA9, AMH, DRD2 303 304 16792 2.552197325 0.996272645 0.465174721 0.463988051 GOTERM_BP_DIRECT GO:0008544~epidermis development 7 1.983002833 0.00429005 SPRR3, KRT16, KRT2, GJB5, HOXB13, SPRR1A, SPRR1B 303 85 16792 4.563929334 0.998818853 0.51744608 0.516126064 GOTERM_BP_DIRECT GO:0006355~regulation of transcription, DNA-templated 42 11.898017 0.004751513 PRDM8, DLX1, HMX3, CIITA, DLX3, PRKAA2, ZNF492, CITED1, AIRE, HOXD1, GFI1, SP140, MYRFL, HOXB13, ELAVL2, HOXC10, SOX2, ZNF80, HOXC4, HOXC9, DRGX, VENTX, NKX3-1, ZNF683, BHLHA9, ZNF880, EMX1, IZUMO2, ZNF285, PAX4, PAX5, DMRTA2, POU2AF1, ZNF813, TRNP1, ZSCAN4, SP8, HOXB2, HOXD3, PTF1A, ZNF334, NEUROG3 303 1504 16792 1.547609016 0.999429005 0.532169497 0.530811921 GOTERM_BP_DIRECT GO:0009813~flavonoid biosynthetic process 4 1.133144476 0.005233427 UGT2B10, UGT1A1, UGT2B4, UGT2A3 303 20 16792 11.08382838 0.999732813 0.547067522 0.545671942 GOTERM_BP_DIRECT GO:0021796~cerebral cortex regionalization 3 0.849858357 0.006377772 EOMES, EMX1, DMRTA2 303 7 16792 23.75106082 0.999956046 0.625021627 0.623427184 GOTERM_BP_DIRECT GO:0052696~flavonoid glucuronidation 4 1.133144476 0.006884985 UGT2B10, UGT1A1, UGT2B4, UGT2A3 303 22 16792 10.07620762 0.999980263 0.635038623 0.633418626 GOTERM_BP_DIRECT GO:0007420~brain development 10 2.83286119 0.007567144 EOMES, DMBX1, HMX3, DMRTA2, CITED1, ZIC2, FOXG1, NNAT, SLC17A8, SLC38A3 303 190 16792 2.916796943 0.99999328 0.659182338 0.65750075 GOTERM_BP_DIRECT GO:0006690~icosanoid metabolic process 3 0.849858357 0.008403146 CYP4F2, PLA2G4A, CYP4F8 303 8 16792 20.78217822 0.999998207 0.690925452 0.689162887 GOTERM_BP_DIRECT GO:0009954~proximal/distal pattern formation 4 1.133144476 0.008812825 DLX1, SP8, HOXC11, HOXC10 303 24 16792 9.236523652 0.999999062 0.690925452 0.689162887 GOTERM_BP_DIRECT GO:0070234~positive regulation of T cell apoptotic process 3 0.849858357 0.010676485 CCL5, PDCD1, IDO1 303 9 16792 18.4730473 0.999999951 0.785859957 0.783855213 GOTERM_BP_DIRECT GO:0031018~endocrine pancreas development 4 1.133144476 0.011026096 RFX6, PAX4, INSM1, NEUROG3 303 26 16792 8.526021833 0.999999972 0.785859957 0.783855213 GOTERM_BP_DIRECT GO:0001656~metanephros development 4 1.133144476 0.012242054 FOXC2, CITED1, HOXC11, NKX3-1 303 27 16792 8.210243247 0.999999996 0.834588759 0.832459706 GOTERM_BP_DIRECT GO:0048149~behavioral response to ethanol 3 0.849858357 0.015929264 CHRNA7, CHRFAM7A, DRD2 303 11 16792 15.11431143 1 0.955491082 0.953053605 GOTERM_BP_DIRECT GO:0006644~phospholipid metabolic process 5 1.416430595 0.01603395 PLA2G2D, PLA2G12B, RARRES3, PLA2G3, PLA2G4A 303 54 16792 5.131402029 1 0.955491082 0.953053605 GOTERM_BP_DIRECT GO:0007267~cell-cell signaling 11 3.116147309 0.016937313 BST2, PYY, CCL5, PCDH8, TNFSF9, NMUR2, FASLG, CXCL13, AMH, TAC1, EREG 303 254 16792 2.400041579 1 0.955491082 0.953053605 GOTERM_BP_DIRECT GO:0015711~organic anion transport 3 0.849858357 0.018890449 SLCO1B1, SLC22A31, SLC22A11 303 12 16792 13.85478548 1 0.955491082 0.953053605 GOTERM_BP_DIRECT GO:0045744~negative regulation of G-protein coupled receptor protein signaling pathway 3 0.849858357 0.018890449 RGS13, CCL5, KLK14 303 12 16792 13.85478548 1 0.955491082 0.953053605 GOTERM_BP_DIRECT GO:0019725~cellular homeostasis 3 0.849858357 0.018890449 SLC22A12, MUC17, ABCA12 303 12 16792 13.85478548 1 0.955491082 0.953053605 GOTERM_BP_DIRECT GO:0043616~keratinocyte proliferation 3 0.849858357 0.018890449 SDR16C5, KRT2, EREG 303 12 16792 13.85478548 1 0.955491082 0.953053605 GOTERM_BP_DIRECT GO:0021846~cell proliferation in forebrain 3 0.849858357 0.018890449 FABP7, ARX, WNT7A 303 12 16792 13.85478548 1 0.955491082 0.953053605 GOTERM_BP_DIRECT GO:0006366~transcription from RNA polymerase II promoter 17 4.815864023 0.023543001 TFAP2A, FOXC2, DLX3, FOXD1, AIRE, ONECUT3, FOXI1, PAX5, BARX2, HOXC11, SOX2, NEUROD2, RFX6, POU2AF1, PAX9, PTF1A, NEUROG3 303 513 16792 1.836501779 1 1 0.998085514 GOTERM_BP_DIRECT GO:0002009~morphogenesis of an epithelium 3 0.849858357 0.025438641 KRT16, CA9, SERPINB5 303 14 16792 11.87553041 1 1 0.998085514 GOTERM_BP_DIRECT GO:0006874~cellular calcium ion homeostasis 6 1.699716714 0.026232587 CCL5, CHRNA7, CHRFAM7A, GRIK2, DRD2, DRD5 303 93 16792 3.575428511 1 1 0.998085514 GOTERM_BP_DIRECT GO:0007271~synaptic transmission, cholinergic 4 1.133144476 0.028526627 CHRM1, CHRNA7, CHRFAM7A, HTR3A 303 37 16792 5.991258585 1 1 0.998085514 GOTERM_BP_DIRECT GO:0045597~positive regulation of cell differentiation 4 1.133144476 0.028526627 EOMES, SOX2, PAX4, INSM1 303 37 16792 5.991258585 1 1 0.998085514 GOTERM_BP_DIRECT GO:0032496~response to lipopolysaccharide 8 2.266288952 0.02901214 UGT1A1, CITED1, GJB6, CYP1A1, FASLG, CXCL13, TAC1, IDO1 303 164 16792 2.703372776 1 1 0.998085514 GOTERM_BP_DIRECT GO:0007631~feeding behavior 4 1.133144476 0.030570781 PYY, NMUR2, GCG, DRD2 303 38 16792 5.833593886 1 1 0.998085514 GOTERM_BP_DIRECT GO:0001756~somitogenesis 4 1.133144476 0.032689992 FOXC2, PCDH8, TCAP, NKX3-1 303 39 16792 5.684014555 1 1 0.998085514 GOTERM_BP_DIRECT GO:0052695~cellular glucuronidation 3 0.849858357 0.0327657 UGT1A1, UGT2B4, UGT2A3 303 16 16792 10.39108911 1 1 0.998085514 GOTERM_BP_DIRECT GO:0001988~positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure 2 0.566572238 0.03564711 CHRNA7, CHRFAM7A 303 2 16792 55.41914191 1 1 0.998085514 GOTERM_BP_DIRECT GO:0002302~CD8-positive, alpha-beta T cell differentiation involved in immune response 2 0.566572238 0.03564711 EOMES, IFNG 303 2 16792 55.41914191 1 1 0.998085514 GOTERM_BP_DIRECT GO:0007218~neuropeptide signaling pathway 6 1.699716714 0.035674519 PYY, PCSK1N, GPR143, NXPH4, NMUR2, TAC1 303 101 16792 3.292226252 1 1 0.998085514 GOTERM_BP_DIRECT GO:0000122~negative regulation of transcription from RNA polymerase II promoter 21 5.949008499 0.036550299 EOMES, TFAP2A, ZNF683, DLX1, FOXC2, CIITA, OSR1, GFI1, ARX, NR1H4, PAX4, FASLG, PAX5, BARX2, SOX2, DMBX1, IFNG, INSM1, FEZF1, HOXC8, NEUROG3 303 720 16792 1.616391639 1 1 0.998085514 GOTERM_BP_DIRECT GO:0036148~phosphatidylglycerol acyl-chain remodeling 3 0.849858357 0.040808156 PLA2G2D, PLA2G3, PLA2G4A 303 18 16792 9.236523652 1 1 0.998085514 GOTERM_BP_DIRECT GO:0045954~positive regulation of natural killer cell mediated cytotoxicity 3 0.849858357 0.040808156 LAG3, KLRK1, CRTAM 303 18 16792 9.236523652 1 1 0.998085514 GOTERM_BP_DIRECT GO:0045089~positive regulation of innate immune response 3 0.849858357 0.040808156 GBP5, CCL5, EREG 303 18 16792 9.236523652 1 1 0.998085514 GOTERM_BP_DIRECT GO:0061436~establishment of skin barrier 3 0.849858357 0.040808156 KRT16, ABCA12, ALOXE3 303 18 16792 9.236523652 1 1 0.998085514 GOTERM_BP_DIRECT GO:0006955~immune response 14 3.966005666 0.041305919 SBSPON, CIITA, AIRE, GZMA, FASLG, CXCL13, KIR2DL3, GZMH, AIM2, IFNG, CCL5, ACKR4, TNFSF9, CEACAM8 303 421 16792 1.842916833 1 1 0.998085514 GOTERM_BP_DIRECT GO:0015701~bicarbonate transport 4 1.133144476 0.04439672 CA5A, CA4, CA9, SLC26A9 303 44 16792 5.03810381 1 1 0.998085514 GOTERM_BP_DIRECT GO:0030216~keratinocyte differentiation 5 1.416430595 0.048048234 SPRR3, KRT16, SPRR1A, SPRR1B, EREG 303 76 16792 3.645996179 1 1 0.998085514 GOTERM_BP_DIRECT GO:0009615~response to virus 6 1.699716714 0.048519665 BST2, IFNG, BTBD17, CCL5, CYP1A1, SPACA3 303 110 16792 3.022862286 1 1 0.998085514 GOTERM_BP_DIRECT GO:0030101~natural killer cell activation 3 0.849858357 0.049506052 NCR1, KLRK1, ULBP2 303 20 16792 8.312871287 1 1 0.998085514 GOTERM_BP_DIRECT GO:0045944~positive regulation of transcription from RNA polymerase II promoter 26 7.365439093 0.050027149 FOXC2, CIITA, DLX3, CITED1, AIRE, ONECUT3, FOXI1, BARX2, HOXC11, SOX2, NEUROD2, DRD2, NKX3-1, EOMES, TFAP2A, FOXD1, OSR1, NR1H4, WNT7A, PAX5, IFNG, RFX6, LMX1A, PAX9, PTF1A, NEUROG3 303 981 16792 1.468804984 1 1 0.998085514 GOTERM_BP_DIRECT GO:0045666~positive regulation of neuron differentiation 5 1.416430595 0.051981898 NEUROD2, IFNG, HOXD3, FEZF1, NEUROG3 303 78 16792 3.552509097 1 1 0.998085514 GOTERM_BP_DIRECT GO:0016055~Wnt signaling pathway 8 2.266288952 0.052593845 DKK4, WNT11, PRKAA2, WIF1, WNT7A, APCDD1, DRD2, RSPO4 303 187 16792 2.370872381 1 1 0.998085514 GOTERM_BP_DIRECT GO:0050954~sensory perception of mechanical stimulus 2 0.566572238 0.052992826 IFNG, DRGX 303 3 16792 36.94609461 1 1 0.998085514 GOTERM_BP_DIRECT GO:0051712~positive regulation of killing of cells of other organism 2 0.566572238 0.052992826 FCER2, IFNG 303 3 16792 36.94609461 1 1 0.998085514 GOTERM_BP_DIRECT GO:0031223~auditory behavior 2 0.566572238 0.052992826 SLITRK6, DRD2 303 3 16792 36.94609461 1 1 0.998085514 GOTERM_BP_DIRECT GO:0016338~calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules 3 0.849858357 0.05408297 CLDN10, CLDN8, CLDN18 303 21 16792 7.917020273 1 1 0.998085514 GOTERM_BP_DIRECT GO:0032094~response to food 3 0.849858357 0.05408297 CHRNA7, CYP1A1, CHRFAM7A 303 21 16792 7.917020273 1 1 0.998085514 GOTERM_BP_DIRECT GO:0042060~wound healing 5 1.416430595 0.05608619 SPRR3, TFF2, TFF1, EREG, DRD5 303 80 16792 3.46369637 1 1 0.998085514 GOTERM_BP_DIRECT GO:0043252~sodium-independent organic anion transport 3 0.849858357 0.063658866 SLC22A12, SLCO1B1, SLC22A11 303 23 16792 7.228583728 1 1 0.998085514 GOTERM_BP_DIRECT GO:0007417~central nervous system development 6 1.699716714 0.065613986 DMBX1, PCP4, VNN1, VNN2, NMUR2, NEUROG3 303 120 16792 2.770957096 1 1 0.998085514 GOTERM_BP_DIRECT GO:0030178~negative regulation of Wnt signaling pathway 4 1.133144476 0.066823109 DKK4, CITED1, WIF1, APCDD1 303 52 16792 4.263010916 1 1 0.998085514 GOTERM_BP_DIRECT GO:0019233~sensory perception of pain 4 1.133144476 0.066823109 MME, HOXD1, TAC1, ALOXE3 303 52 16792 4.263010916 1 1 0.998085514 GOTERM_BP_DIRECT GO:0050830~defense response to Gram-positive bacterium 5 1.416430595 0.067085018 KLRK1, SPACA3, REG3G, TAC1, LYZL4 303 85 16792 3.259949524 1 1 0.998085514 GOTERM_BP_DIRECT GO:0016042~lipid catabolic process 5 1.416430595 0.067085018 PLA2G2D, PLA2G12B, RARRES3, PNPLA3, PLA2G3 303 85 16792 3.259949524 1 1 0.998085514 GOTERM_BP_DIRECT GO:0010951~negative regulation of endopeptidase activity 6 1.699716714 0.06748686 BST2, PCSK1N, HMSD, KNG1, SERPINB5, WFDC13 303 121 16792 2.748056624 1 1 0.998085514 GOTERM_BP_DIRECT GO:0034341~response to interferon-gamma 3 0.849858357 0.068644869 BST2, CIITA, CITED1 303 24 16792 6.927392739 1 1 0.998085514 GOTERM_BP_DIRECT GO:0007548~sex differentiation 3 0.849858357 0.068644869 DMRTA2, WNT7A, AMH 303 24 16792 6.927392739 1 1 0.998085514 GOTERM_BP_DIRECT GO:0036152~phosphatidylethanolamine acyl-chain remodeling 3 0.849858357 0.068644869 PLA2G2D, PLA2G3, PLA2G4A 303 24 16792 6.927392739 1 1 0.998085514 GOTERM_BP_DIRECT GO:0003009~skeletal muscle contraction 3 0.849858357 0.068644869 TNNT1, TNNC2, TCAP 303 24 16792 6.927392739 1 1 0.998085514 GOTERM_BP_DIRECT GO:0006508~proteolysis 15 4.249291785 0.068991218 NAPSA, OVCH1, MME, F11, KLK14, KLK10, KLK11, CNDP1, MMP20, AGBL4, CAPN14, PRSS50, MEP1B, XPNPEP2, ANPEP 303 500 16792 1.662574257 1 1 0.998085514 GOTERM_BP_DIRECT GO:0006928~movement of cell or subcellular component 5 1.416430595 0.069409669 PYY, VNN1, IFNG, VNN2, SERPINB5 303 86 16792 3.222043135 1 1 0.998085514 GOTERM_BP_DIRECT GO:0021559~trigeminal nerve development 2 0.566572238 0.070027561 TFAP2A, DRGX 303 4 16792 27.70957096 1 1 0.998085514 GOTERM_BP_DIRECT GO:0070858~negative regulation of bile acid biosynthetic process 2 0.566572238 0.070027561 NR1H4, MALRD1 303 4 16792 27.70957096 1 1 0.998085514 GOTERM_BP_DIRECT GO:0060112~generation of ovulation cycle rhythm 2 0.566572238 0.070027561 CHRNA7, CHRFAM7A 303 4 16792 27.70957096 1 1 0.998085514 GOTERM_BP_DIRECT GO:0003310~pancreatic A cell differentiation 2 0.566572238 0.070027561 RFX6, INSM1 303 4 16792 27.70957096 1 1 0.998085514 GOTERM_BP_DIRECT GO:0032224~positive regulation of synaptic transmission, cholinergic 2 0.566572238 0.070027561 IFNG, TAC1 303 4 16792 27.70957096 1 1 0.998085514 GOTERM_BP_DIRECT GO:0007320~insemination 2 0.566572238 0.070027561 SEMG1, TAC1 303 4 16792 27.70957096 1 1 0.998085514 GOTERM_BP_DIRECT GO:0033634~positive regulation of cell-cell adhesion mediated by integrin 2 0.566572238 0.070027561 CCL5, CXCL13 303 4 16792 27.70957096 1 1 0.998085514 GOTERM_BP_DIRECT GO:0019369~arachidonic acid metabolic process 3 0.849858357 0.073754572 CYP4F2, PLA2G4A, ALOXE3 303 25 16792 6.65029703 1 1 0.998085514 GOTERM_BP_DIRECT GO:0019433~triglyceride catabolic process 3 0.849858357 0.073754572 FABP3, FABP7, PNPLA3 303 25 16792 6.65029703 1 1 0.998085514 GOTERM_BP_DIRECT GO:0007568~aging 7 1.983002833 0.07786397 CIITA, KRT16, FOXG1, GJB6, CYP1A1, PAX5, AMH 303 165 16792 2.351115112 1 1 0.998085514 GOTERM_BP_DIRECT GO:0006954~inflammatory response 12 3.399433428 0.0798816 GBP5, CIITA, PLA2G2D, AIM2, VNN1, MEP1B, KRT16, CCL5, NR1H4, CXCL13, TAC1, KNG1 303 379 16792 1.754695786 1 1 0.998085514 GOTERM_BP_DIRECT GO:0071346~cellular response to interferon-gamma 4 1.133144476 0.082985039 GBP5, CIITA, DAPK1, CCL5 303 57 16792 3.88906259 1 1 0.998085514 GOTERM_BP_DIRECT GO:0009887~organ morphogenesis 5 1.416430595 0.084209552 PAX9, APLP1, PAX4, PAX5, EREG 303 92 16792 3.011909887 1 1 0.998085514 GOTERM_BP_DIRECT GO:0042476~odontogenesis 3 0.849858357 0.084321136 OSR1, PAX9, AQP5 303 27 16792 6.157682435 1 1 0.998085514 GOTERM_BP_DIRECT GO:0036151~phosphatidylcholine acyl-chain remodeling 3 0.849858357 0.084321136 PLA2G2D, PLA2G3, PLA2G4A 303 27 16792 6.157682435 1 1 0.998085514 GOTERM_BP_DIRECT GO:0017144~drug metabolic process 3 0.849858357 0.084321136 UGT1A1, CYP4F2, CYP1A1 303 27 16792 6.157682435 1 1 0.998085514 GOTERM_BP_DIRECT GO:0046541~saliva secretion 2 0.566572238 0.086756872 CHRM1, AQP5 303 5 16792 22.16765677 1 1 0.998085514 GOTERM_BP_DIRECT GO:0045760~positive regulation of action potential 2 0.566572238 0.086756872 SCN5A, TAC1 303 5 16792 22.16765677 1 1 0.998085514 GOTERM_BP_DIRECT GO:0001714~endodermal cell fate specification 2 0.566572238 0.086756872 EOMES, SOX2 303 5 16792 22.16765677 1 1 0.998085514 GOTERM_BP_DIRECT GO:0051546~keratinocyte migration 2 0.566572238 0.086756872 KRT16, KRT2 303 5 16792 22.16765677 1 1 0.998085514 GOTERM_BP_DIRECT GO:0032225~regulation of synaptic transmission, dopaminergic 2 0.566572238 0.086756872 CHRNA7, CHRFAM7A 303 5 16792 22.16765677 1 1 0.998085514 GOTERM_BP_DIRECT GO:0032715~negative regulation of interleukin-6 production 3 0.849858357 0.089766464 CHRNA7, NR1H4, CHRFAM7A 303 28 16792 5.937765205 1 1 0.998085514 GOTERM_BP_DIRECT GO:0007275~multicellular organism development 15 4.249291785 0.090012144 BHLHA9, ST6GAL2, FZD10, PAX5, BST2, DKK4, TCL1A, WNT11, WIF1, HOXC4, HOXB2, PDCD1, VENTX, HOXC6, NKX3-1 303 521 16792 1.595560708 1 1 0.998085514 GOTERM_BP_DIRECT GO:0001666~response to hypoxia 7 1.983002833 0.09070379 PKLR, CHRNA7, CYP1A1, CA9, CHRFAM7A, DRD2, SLC6A4 303 172 16792 2.255430194 1 1 0.998085514 GOTERM_BP_DIRECT GO:0030182~neuron differentiation 5 1.416430595 0.092142716 WNT11, HOXD1, NNAT, FZD10, HOXC8 303 95 16792 2.916796943 1 1 0.998085514 GOTERM_BP_DIRECT GO:0006351~transcription, DNA-templated 44 12.46458924 0.094406047 PRDM8, HMX3, CIITA, PRKAA2, ZNF492, CITED1, HOXD1, GFI1, FOXG1, ARX, FASLG, HOXB13, HOXC10, DMBX1, ZNF80, ZIC2, HOXC5, HOXC4, HOXC9, HOXC8, FEZF1, DRGX, HOXC6, NKX3-1, EOMES, ZNF683, BHLHA9, ZNF285, OSR1, PAX4, NR1H4, PAX5, LMX1A, TBX10, ZNF813, TRNP1, PAX9, ZSCAN4, SP8, HOXB2, HOXD3, INSM1, ZNF334, FOXD4L1 303 1955 16792 1.247285035 1 1 0.998085514 GOTERM_BP_DIRECT GO:0042113~B cell activation 3 0.849858357 0.095312415 BST2, CHRNA7, CHRFAM7A 303 29 16792 5.733014681 1 1 0.998085514 GOTERM_BP_DIRECT GO:0035774~positive regulation of insulin secretion involved in cellular response to glucose stimulus 3 0.849858357 0.095312415 RFX6, NR1H4, GCG 303 29 16792 5.733014681 1 1 0.998085514 GOTERM_BP_DIRECT GO:0001662~behavioral fear response 3 0.849858357 0.095312415 NEUROD2, CCK, GRIK2 303 29 16792 5.733014681 1 1 0.998085514