Gene Symbol,Description,Relevance score
BECN1,Beclin 1,56.6
ATG5,Autophagy Related 5,48.3
VMA21,Vacuolar ATPase Assembly Factor VMA21,45.58
ATG14,Autophagy Related 14,40.84
ATG16L1,Autophagy Related 16 Like 1,38.36
ULK1,Unc-51 Like Autophagy Activating Kinase 1,36.84
ATG7,Autophagy Related 7,36.19
ATG12,Autophagy Related 12,35.99
ATG3,Autophagy Related 3,34.99
EPG5,Ectopic P-Granules Autophagy Protein 5 Homolog,33.88
SQSTM1,Sequestosome 1,31.37
LAMP2,Lysosomal Associated Membrane Protein 2,30.55
ATG4B,Autophagy Related 4B Cysteine Peptidase,30.38
ATG13,Autophagy Related 13,29.5
MTOR,Mechanistic Target Of Rapamycin Kinase,29.48
AMBRA1,Autophagy And Beclin 1 Regulator 1,27.87
ATG4A,Autophagy Related 4A Cysteine Peptidase,27.62
ATG4C,Autophagy Related 4C Cysteine Peptidase,26.89
ATG10,Autophagy Related 10,26.86
ATG4D,Autophagy Related 4D Cysteine Peptidase,26.82
ATG9A,Autophagy Related 9A,26.75
ATG9B,Autophagy Related 9B,25.63
PIK3C3,Phosphatidylinositol 3-Kinase Catalytic Subunit Type 3,24.84
ATG2B,Autophagy Related 2B,23.85
MAP1LC3A,Microtubule Associated Protein 1 Light Chain 3 Alpha,23.07
MAP1LC3B,Microtubule Associated Protein 1 Light Chain 3 Beta,22.96
ULK2,Unc-51 Like Autophagy Activating Kinase 2,22.88
HMGB1,High Mobility Group Box 1,22.21
ATG16L2,Autophagy Related 16 Like 2,22.19
DRAM1,DNA Damage Regulated Autophagy Modulator 1,21.13
ATG2A,Autophagy Related 2A,21.01
GABARAP,GABA Type A Receptor-Associated Protein,18.65
DRAM2,DNA Damage Regulated Autophagy Modulator 2,18.64
PIK3R4,Phosphoinositide-3-Kinase Regulatory Subunit 4,18.64
RB1CC1,RB1 Inducible Coiled-Coil 1,18.26
WIPI1,"WD Repeat Domain, Phosphoinositide Interacting 1",18.02
GABARAPL1,GABA Type A Receptor Associated Protein Like 1,17.87
TP53,Tumor Protein P53,17.86
ATG101,Autophagy Related 101,17.29
BCL2,BCL2 Apoptosis Regulator,16.87
UVRAG,UV Radiation Resistance Associated,16.72
MAP1LC3C,Microtubule Associated Protein 1 Light Chain 3 Gamma,16.52
TFEB,Transcription Factor EB,16.03
GABARAPL2,GABA Type A Receptor Associated Protein Like 2,15.7
RUBCNL,Rubicon Like Autophagy Enhancer,15.7
WIPI2,"WD Repeat Domain, Phosphoinositide Interacting 2",15.69
C9orf72,C9orf72-SMCR8 Complex Subunit,15.45
RUBCN,Rubicon Autophagy Regulator,15.39
AKT1,AKT Serine/Threonine Kinase 1,14.99
SH3GLB1,"SH3 Domain Containing GRB2 Like, Endophilin B1",14.82
HTT,Huntingtin,14.8
SIRT1,Sirtuin 1,14.73
APP,Amyloid Beta Precursor Protein,14.51
PRKN,Parkin RBR E3 Ubiquitin Protein Ligase,14.12
LRRK2,Leucine Rich Repeat Kinase 2,13.94
NBR1,NBR1 Autophagy Cargo Receptor,13.54
TP53INP2,Tumor Protein P53 Inducible Nuclear Protein 2,13.49
PRKAA1,Protein Kinase AMP-Activated Catalytic Subunit Alpha 1,13.36
PINK1,PTEN Induced Kinase 1,13.2
GSK3B,Glycogen Synthase Kinase 3 Beta,12.94
SNCA,Synuclein Alpha,12.94
CASP3,Caspase 3,12.85
SOGA1,"Suppressor Of Glucose, Autophagy Associated 1",12.71
MAPK8,Mitogen-Activated Protein Kinase 8,12.7
HDAC6,Histone Deacetylase 6,12.65
NRBF2,Nuclear Receptor Binding Factor 2,12.59
PRKAA2,Protein Kinase AMP-Activated Catalytic Subunit Alpha 2,12.45
PSEN1,Presenilin 1,12.13
IRGM,Immunity Related GTPase M,11.97
MAPK14,Mitogen-Activated Protein Kinase 14,11.94
WDR45,WD Repeat Domain 45,11.71
STX17,Syntaxin 17,11.66
OPTN,Optineurin,11.41
KEAP1,Kelch Like ECH Associated Protein 1,11.3
CALCOCO2,Calcium Binding And Coiled-Coil Domain 2,11.2
ITPR1,"Inositol 1,4,5-Trisphosphate Receptor Type 1",11.14
FOXO3,Forkhead Box O3,11.1
DAPK1,Death Associated Protein Kinase 1,11.08
TECPR2,Tectonin Beta-Propeller Repeat Containing 2,11.06
VCP,Valosin Containing Protein,11
UBQLN1,Ubiquilin 1,10.97
IL1B,Interleukin 1 Beta,10.92
MTMR14,Myotubularin Related Protein 14,10.88
MAPK1,Mitogen-Activated Protein Kinase 1,10.85
VMP1,Vacuole Membrane Protein 1,10.82
CTSD,Cathepsin D,10.75
PIK3CA,"Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha",10.7
ELAPOR1,Endosome-Lysosome Associated Apoptosis And Autophagy Regulator 1,10.62
SNAP29,Synaptosome Associated Protein 29,10.6
RAB7A,"RAB7A, Member RAS Oncogene Family",10.51
BNIP3,BCL2 Interacting Protein 3,10.46
WDFY3,WD Repeat And FYVE Domain Containing 3,10.44
KRAS,"KRAS Proto-Oncogene, GTPase",10.43
CASP8,Caspase 8,10.37
ATXN3,Ataxin 3,10.37
TP53INP1,Tumor Protein P53 Inducible Nuclear Protein 1,10.32
MIR29A,MicroRNA 29a,10.23
CTSB,Cathepsin B,10.23
RPTOR,Regulatory Associated Protein Of MTOR Complex 1,10.13
NFE2L2,"Nuclear Factor, Erythroid 2 Like 2",10.11
ULK3,Unc-51 Like Kinase 3,10.08
GAA,"Glucosidase Alpha, Acid",10.06
TNF,Tumor Necrosis Factor,9.95
CISD2,CDGSH Iron Sulfur Domain 2,9.87
XBP1,X-Box Binding Protein 1,9.82
MAPT,Microtubule Associated Protein Tau,9.76
USP10,Ubiquitin Specific Peptidase 10,9.69
TBK1,TANK Binding Kinase 1,9.69
HSPA8,Heat Shock Protein Family A (Hsp70) Member 8,9.65
PIK3R1,Phosphoinositide-3-Kinase Regulatory Subunit 1,9.64
RPS6KB1,Ribosomal Protein S6 Kinase B1,9.62
LAMP1,Lysosomal Associated Membrane Protein 1,9.6
BAD,BCL2 Associated Agonist Of Cell Death,9.56
GSK3A,Glycogen Synthase Kinase 3 Alpha,9.5
EI24,EI24 Autophagy Associated Transmembrane Protein,9.41
RAB5A,"RAB5A, Member RAS Oncogene Family",9.4
BECN2,Beclin 2,9.33
CYCS,"Cytochrome C, Somatic",9.29
HIF1A,Hypoxia Inducible Factor 1 Subunit Alpha,9.17
TBC1D5,TBC1 Domain Family Member 5,9.13
EIF2AK3,Eukaryotic Translation Initiation Factor 2 Alpha Kinase 3,9.13
MIR34A,MicroRNA 34a,9.1
TECPR1,Tectonin Beta-Propeller Repeat Containing 1,9.1
SMCR8,SMCR8-C9orf72 Complex Subunit,9.01
ERN1,Endoplasmic Reticulum To Nucleus Signaling 1,9
DEPP1,DEPP1 Autophagy Regulator,8.91
TMEM59,Transmembrane Protein 59,8.84
MIR132,MicroRNA 132,8.84
DNM1L,Dynamin 1 Like,8.8
WDR41,WD Repeat Domain 41,8.8
MCOLN1,Mucolipin 1,8.79
STK11,Serine/Threonine Kinase 11,8.74
HRAS,"HRas Proto-Oncogene, GTPase",8.73
SIRT2,Sirtuin 2,8.64
DAP,Death Associated Protein,8.63
PIK3CB,"Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Beta",8.57
IL6,Interleukin 6,8.55
DAPK3,Death Associated Protein Kinase 3,8.52
WDR45B,WD Repeat Domain 45B,8.51
RAB33B,"RAB33B, Member RAS Oncogene Family",8.36
SOD1,Superoxide Dismutase 1,8.35
RAB8A,"RAB8A, Member RAS Oncogene Family",8.31
PLAU,"Plasminogen Activator, Urokinase",8.19
HSPA5,Heat Shock Protein Family A (Hsp70) Member 5,8.16
PICALM,Phosphatidylinositol Binding Clathrin Assembly Protein,8.14
RAF1,"Raf-1 Proto-Oncogene, Serine/Threonine Kinase",8.14
STING1,Stimulator Of Interferon Response CGAMP Interactor 1,8.09
TRIM5,Tripartite Motif Containing 5,8.08
INS,Insulin,8.07
MAPK3,Mitogen-Activated Protein Kinase 3,8.06
EIF2S1,Eukaryotic Translation Initiation Factor 2 Subunit Alpha,8.04
RAB39B,"RAB39B, Member RAS Oncogene Family",8
CASP1,Caspase 1,7.96
GNE,Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase,7.9
MAP3K5,Mitogen-Activated Protein Kinase Kinase Kinase 5,7.82
NOS3,Nitric Oxide Synthase 3,7.74
MIR107,MicroRNA 107,7.72
MAPK9,Mitogen-Activated Protein Kinase 9,7.7
DAPK2,Death Associated Protein Kinase 2,7.69
MIR29B1,MicroRNA 29b-1,7.65
MIR29C,MicroRNA 29c,7.63
JUN,"Jun Proto-Oncogene, AP-1 Transcription Factor Subunit",7.62
MIR146A,MicroRNA 146a,7.6
VDAC1,Voltage Dependent Anion Channel 1,7.6
MIR106B,MicroRNA 106b,7.59
IGF1,Insulin Like Growth Factor 1,7.58
USP13,Ubiquitin Specific Peptidase 13,7.57
ATP12A,ATPase H+/K+ Transporting Non-Gastric Alpha2 Subunit,7.56
ATP4A,ATPase H+/K+ Transporting Subunit Alpha,7.56
SRPK3,SRSF Protein Kinase 3,7.56
CCDC115,Coiled-Coil Domain Containing 115,7.56
TMEM199,Transmembrane Protein 199,7.56
PIK3R2,Phosphoinositide-3-Kinase Regulatory Subunit 2,7.55
FAS,Fas Cell Surface Death Receptor,7.48
FLCN,Folliculin,7.48
CASP7,Caspase 7,7.46
CASP9,Caspase 9,7.45
CASP2,Caspase 2,7.43
TARDBP,TAR DNA Binding Protein,7.39
NFKB1,Nuclear Factor Kappa B Subunit 1,7.38
VPS13A,Vacuolar Protein Sorting 13 Homolog A,7.36
MIR22,MicroRNA 22,7.34
VAMP8,Vesicle Associated Membrane Protein 8,7.33
ZKSCAN3,Zinc Finger With KRAB And SCAN Domains 3,7.25
PDPK1,3-Phosphoinositide Dependent Protein Kinase 1,7.24
BCL2L1,BCL2 Like 1,7.23
RNASEL,Ribonuclease L,7.23
MCL1,"MCL1 Apoptosis Regulator, BCL2 Family Member",7.23
MAP2K1,Mitogen-Activated Protein Kinase Kinase 1,7.23
NOD2,Nucleotide Binding Oligomerization Domain Containing 2,7.21
TRAF6,TNF Receptor Associated Factor 6,7.21
MAPK15,Mitogen-Activated Protein Kinase 15,7.18
KAT5,Lysine Acetyltransferase 5,7.17
NUPR1,"Nuclear Protein 1, Transcriptional Regulator",7.16
EIF2AK4,Eukaryotic Translation Initiation Factor 2 Alpha Kinase 4,7.15
TRAF2,TNF Receptor Associated Factor 2,7.13
PTEN,Phosphatase And Tensin Homolog,7.11
TMEM208,Transmembrane Protein 208,7.1
PRKCD,Protein Kinase C Delta,7.06
GAPDH,Glyceraldehyde-3-Phosphate Dehydrogenase,7.05
DDIT3,DNA Damage Inducible Transcript 3,6.97
IFNG,Interferon Gamma,6.97
CLTC,Clathrin Heavy Chain,6.93
RPS27A,Ribosomal Protein S27a,6.91
TRIM21,Tripartite Motif Containing 21,6.87
TUFM,"Tu Translation Elongation Factor, Mitochondrial",6.84
MEFV,"MEFV Innate Immuity Regulator, Pyrin",6.83
PARK7,Parkinsonism Associated Deglycase,6.81
TNFRSF1A,TNF Receptor Superfamily Member 1A,6.8
FOXO1,Forkhead Box O1,6.77
UCHL1,Ubiquitin C-Terminal Hydrolase L1,6.75
CDKN2A,Cyclin Dependent Kinase Inhibitor 2A,6.74
HSPA4,Heat Shock Protein Family A (Hsp70) Member 4,6.73
SBF2,SET Binding Factor 2,6.73
STUB1,STIP1 Homology And U-Box Containing Protein 1,6.73
CASP6,Caspase 6,6.72
ATP13A2,ATPase Cation Transporting 13A2,6.72
SUPT20H,"SPT20 Homolog, SAGA Complex Component",6.71
MAPK10,Mitogen-Activated Protein Kinase 10,6.69
PHF23,PHD Finger Protein 23,6.69
BRAF,"B-Raf Proto-Oncogene, Serine/Threonine Kinase",6.69
USP36,Ubiquitin Specific Peptidase 36,6.67
CAV1,Caveolin 1,6.66
FIG4,FIG4 Phosphoinositide 5-Phosphatase,6.65
VAC14,VAC14 Component Of PIKFYVE Complex,6.65
PPARG,Peroxisome Proliferator Activated Receptor Gamma,6.65
LGALS8,Galectin 8,6.65
MFN2,Mitofusin 2,6.65
SLC2A3,Solute Carrier Family 2 Member 3,6.61
UBQLN2,Ubiquilin 2,6.6
RELA,"RELA Proto-Oncogene, NF-KB Subunit",6.59
INSR,Insulin Receptor,6.5
IFI16,Interferon Gamma Inducible Protein 16,6.49
STAT3,Signal Transducer And Activator Of Transcription 3,6.47
HDAC10,Histone Deacetylase 10,6.47
PRNP,Prion Protein,6.47
CTNNB1,Catenin Beta 1,6.44
ABL1,"ABL Proto-Oncogene 1, Non-Receptor Tyrosine Kinase",6.4
TUBA1B,Tubulin Alpha 1b,6.36
FOXK1,Forkhead Box K1,6.34
IRS1,Insulin Receptor Substrate 1,6.34
CDK5,Cyclin Dependent Kinase 5,6.33
TMEM74,Transmembrane Protein 74,6.33
BOK,BCL2 Family Apoptosis Regulator BOK,6.33
IL10,Interleukin 10,6.28
HFE,Homeostatic Iron Regulator,6.28
TTR,Transthyretin,6.28
ATF4,Activating Transcription Factor 4,6.28
NPC1,NPC Intracellular Cholesterol Transporter 1,6.26
UBC,Ubiquitin C,6.26
BAX,"BCL2 Associated X, Apoptosis Regulator",6.25
ACBD5,Acyl-CoA Binding Domain Containing 5,6.23
TSC2,TSC Complex Subunit 2,6.22
AR,Androgen Receptor,6.2
HMOX1,Heme Oxygenase 1,6.19
TUBB,Tubulin Beta Class I,6.18
IL10RA,Interleukin 10 Receptor Subunit Alpha,6.18
MPO,Myeloperoxidase,6.17
A2M,Alpha-2-Macroglobulin,6.17
UNC5C,Unc-5 Netrin Receptor C,6.17
MIR328,MicroRNA 328,6.17
MIR298,MicroRNA 298,6.17
SCA18,Spinocerebellar Ataxia 18 (Sensory With Neurogenic Muscular Atrophy),6.17
SCA25,Spinocerebellar Ataxia 25,6.17
SCA30,Spinocerebellar Ataxia 30,6.17
AD10,Alzheimer Disease-10,6.17
AD11,Alzheimer Disease-11,6.17
AD12,Alzheimer Disease 12,6.17
AD13,Alzheimer Disease-13,6.17
AD14,Alzheimer Disease 14,6.17
AD15,Alzheimer Disease-15,6.17
AD16,Alzheimer Disease 16,6.17
AD17,Alzheimer Disease 17,6.17
AD5,Alzheimer Disease 5,6.17
AD6,Alzheimer Disease 6,6.17
AD7,Alzheimer Disease 7,6.17
AD8,Alzheimer Disease 8,6.17
ATN1,Atrophin 1,6.17
PARP1,Poly(ADP-Ribose) Polymerase 1,6.15
NDRG2,NDRG Family Member 2,6.13
BNIP3L,BCL2 Interacting Protein 3 Like,6.13
HDAC1,Histone Deacetylase 1,6.12
APAF1,Apoptotic Peptidase Activating Factor 1,6.11
EGFR,Epidermal Growth Factor Receptor,6.1
SOD2,Superoxide Dismutase 2,6.08
PLEKHM2,Pleckstrin Homology And RUN Domain Containing M2,6.06
AGER,Advanced Glycosylation End-Product Specific Receptor,6.05
GFAP,Glial Fibrillary Acidic Protein,6.01
MLST8,"MTOR Associated Protein, LST8 Homolog",5.96
TBC1D17,TBC1 Domain Family Member 17,5.96
CLU,Clusterin,5.91
RAB1A,"RAB1A, Member RAS Oncogene Family",5.9
NQO1,NAD(P)H Quinone Dehydrogenase 1,5.9
ATXN7,Ataxin 7,5.88
ELAPOR2,Endosome-Lysosome Associated Apoptosis And Autophagy Regulator Family Member 2,5.86
CFLAR,CASP8 And FADD Like Apoptosis Regulator,5.84
LGALS3,Galectin 3,5.8
ITPR3,"Inositol 1,4,5-Trisphosphate Receptor Type 3",5.78
TGM2,Transglutaminase 2,5.76
CXCR4,C-X-C Motif Chemokine Receptor 4,5.76
PPARGC1A,PPARG Coactivator 1 Alpha,5.73
BAG3,BAG Cochaperone 3,5.71
SH3BP4,SH3 Domain Binding Protein 4,5.7
OLR1,Oxidized Low Density Lipoprotein Receptor 1,5.69
NGF,Nerve Growth Factor,5.68
RAB7B,"RAB7B, Member RAS Oncogene Family",5.66
CHUK,Component Of Inhibitor Of Nuclear Factor Kappa B Kinase Complex,5.64
NOTCH1,Notch Receptor 1,5.63
TRIM16,Tripartite Motif Containing 16,5.6
S100A8,S100 Calcium Binding Protein A8,5.6
IRS2,Insulin Receptor Substrate 2,5.58
BCL2L11,BCL2 Like 11,5.57
EVA1A,"Eva-1 Homolog A, Regulator Of Programmed Cell Death",5.56
PIM2,"Pim-2 Proto-Oncogene, Serine/Threonine Kinase",5.55
REST,RE1 Silencing Transcription Factor,5.53
CSNK2A2,Casein Kinase 2 Alpha 2,5.53
GSN,Gelsolin,5.51
TP73,Tumor Protein P73,5.5
NGFR,Nerve Growth Factor Receptor,5.5
NTF3,Neurotrophin 3,5.48
DRD2,Dopamine Receptor D2,5.48
TSPO,Translocator Protein,5.48
HCRT,Hypocretin Neuropeptide Precursor,5.46
CREB1,CAMP Responsive Element Binding Protein 1,5.46
DNAJB1,DnaJ Heat Shock Protein Family (Hsp40) Member B1,5.46
RIPK1,Receptor Interacting Serine/Threonine Kinase 1,5.46
EIF2AK2,Eukaryotic Translation Initiation Factor 2 Alpha Kinase 2,5.45
PRKCA,Protein Kinase C Alpha,5.43
PPARA,Peroxisome Proliferator Activated Receptor Alpha,5.43
TPCN2,Two Pore Segment Channel 2,5.43
SLC1A3,Solute Carrier Family 1 Member 3,5.43
TGFB1,Transforming Growth Factor Beta 1,5.43
USP14,Ubiquitin Specific Peptidase 14,5.42
HSP90AA1,Heat Shock Protein 90 Alpha Family Class A Member 1,5.42
MIR93,MicroRNA 93,5.41
TXN,Thioredoxin,5.41
NDUFS4,NADH:Ubiquinone Oxidoreductase Subunit S4,5.37
ESR2,Estrogen Receptor 2,5.35
CALB1,Calbindin 1,5.35
NLRX1,NLR Family Member X1,5.34
TOLLIP,Toll Interacting Protein,5.33
UBQLN4,Ubiquilin 4,5.33
CDK1,Cyclin Dependent Kinase 1,5.31
CLEC16A,C-Type Lectin Domain Containing 16A,5.31
SP1,Sp1 Transcription Factor,5.3
CSNK2A1,Casein Kinase 2 Alpha 1,5.3
ACER2,Alkaline Ceramidase 2,5.24
CACNA1C,Calcium Voltage-Gated Channel Subunit Alpha1 C,5.23
CCT3,Chaperonin Containing TCP1 Subunit 3,5.22
CAMKK2,Calcium/Calmodulin Dependent Protein Kinase Kinase 2,5.2
TIGAR,TP53 Induced Glycolysis Regulatory Phosphatase,5.19
DIRAS3,DIRAS Family GTPase 3,5.18
TLR2,Toll Like Receptor 2,5.18
MAP1B,Microtubule Associated Protein 1B,5.18
TSC1,TSC Complex Subunit 1,5.15
MAP2K2,Mitogen-Activated Protein Kinase Kinase 2,5.15
IL1A,Interleukin 1 Alpha,5.15
WASHC1,WASH Complex Subunit 1,5.14
DCN,Decorin,5.13
BSN,Bassoon Presynaptic Cytomatrix Protein,5.13
NTRK2,Neurotrophic Receptor Tyrosine Kinase 2,5.12
RNF166,Ring Finger Protein 166,5.12
RAB12,"RAB12, Member RAS Oncogene Family",5.12
MIR210,MicroRNA 210,5.11
CSNK1A1,Casein Kinase 1 Alpha 1,5.11
MEG3,Maternally Expressed 3,5.1
FYCO1,FYVE And Coiled-Coil Domain Autophagy Adaptor 1,5.1
DRD3,Dopamine Receptor D3,5.09
MTMR3,Myotubularin Related Protein 3,5.09
FUS,FUS RNA Binding Protein,5.06
SRC,"SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase",5.05
NOS2,Nitric Oxide Synthase 2,5.05
ATXN1,Ataxin 1,5.04
TRIM13,Tripartite Motif Containing 13,5.04
ALB,Albumin,5.03
TRIM23,Tripartite Motif Containing 23,5.02
BIRC5,Baculoviral IAP Repeat Containing 5,5.02
LEP,Leptin,5.01
RETREG1,Reticulophagy Regulator 1,5.01
MT3,Metallothionein 3,5.01