#node1 node2 node1_string_internal_id node2_string_internal_id node1_external_id node2_external_id neighborhood_on_chromosome gene_fusion phylogenetic_cooccurrence homology coexpression experimentally_determined_interaction database_annotated automated_textmining combined_score CCNA2 CDK6 4436109 4435642 9606.ENSP00000274026 9606.ENSP00000265734 0 0.003 0 0 0.163 0.994 0.720 0.769 0.999 AKT1 GSK3B 4450372 4439717 9606.ENSP00000451828 9606.ENSP00000324806 0 0 0.218 0.576 0.049 0.995 0.900 0.918 0.999 CCNA2 CDK2 4436109 4435732 9606.ENSP00000274026 9606.ENSP00000266970 0 0.006 0 0 0.403 0.998 0.900 0.973 0.999 HSPA8 HSP90AA1 4449616 4440643 9606.ENSP00000432083 9606.ENSP00000335153 0 0 0 0 0.771 0.730 0.900 0.929 0.999 XIAP CASP3 4443692 4438651 9606.ENSP00000360242 9606.ENSP00000311032 0 0 0 0 0.061 0.947 0.900 0.937 0.999 AKT1 HSP90AA1 4450372 4440643 9606.ENSP00000451828 9606.ENSP00000335153 0 0 0 0 0.061 0.806 0.900 0.920 0.998 RXRA RARA 4449061 4434338 9606.ENSP00000419692 9606.ENSP00000254066 0 0 0 0.773 0.088 0.979 0.900 0.747 0.998 HRAS EGFR 4448459 4436186 9606.ENSP00000407586 9606.ENSP00000275493 0 0 0 0 0.052 0.329 0.900 0.972 0.998 APAF1 CASP3 4450251 4438651 9606.ENSP00000448165 9606.ENSP00000311032 0 0 0 0 0.067 0.825 0.900 0.935 0.998 CDC42 TNK2 4446990 4445619 9606.ENSP00000383118 9606.ENSP00000371341 0 0 0 0 0 0.974 0.900 0.641 0.998 FKBP1A TGFBR1 4446979 4444485 9606.ENSP00000383003 9606.ENSP00000364133 0 0 0 0 0 0.972 0.900 0.639 0.998 MAPKAPK2 MAPK14 4442808 4433482 9606.ENSP00000356070 9606.ENSP00000229795 0 0 0.350 0.592 0.110 0.950 0.900 0.850 0.997 RXRA PPARG 4449061 4436745 9606.ENSP00000419692 9606.ENSP00000287820 0 0 0 0.694 0.061 0.961 0.900 0.821 0.997 PTPN11 EGFR 4441096 4436186 9606.ENSP00000340944 9606.ENSP00000275493 0 0 0 0 0 0.800 0.900 0.852 0.996 SHMT1 ATIC 4439233 4433672 9606.ENSP00000318868 9606.ENSP00000236959 0.122 0 0 0 0.737 0.406 0.900 0.721 0.995 HRAS MAP2K1 4448459 4437859 9606.ENSP00000407586 9606.ENSP00000302486 0 0 0 0 0.134 0.586 0.900 0.857 0.994 KIF11 AURKA 4434801 4432988 9606.ENSP00000260731 9606.ENSP00000216911 0 0 0 0 0.940 0.482 0 0.831 0.994 CDC42 MAPK8 4446990 4446429 9606.ENSP00000383118 9606.ENSP00000378974 0 0 0 0 0.063 0.574 0.900 0.861 0.993 RHOA MAPK8 4448110 4446429 9606.ENSP00000400175 9606.ENSP00000378974 0 0 0 0 0.062 0.735 0.900 0.765 0.993 NR1H4 RXRA 4450225 4449061 9606.ENSP00000447149 9606.ENSP00000419692 0 0 0 0.668 0.062 0.904 0.900 0.745 0.992 JAK2 PTPN11 4445579 4441096 9606.ENSP00000371067 9606.ENSP00000340944 0 0 0 0 0.062 0.525 0.900 0.849 0.992 HRAS SRC 4448459 4444215 9606.ENSP00000407586 9606.ENSP00000362680 0 0 0 0 0.107 0.472 0.900 0.833 0.991 AKT1 ESR1 4450372 4448358 9606.ENSP00000451828 9606.ENSP00000405330 0 0 0 0 0.055 0.407 0.900 0.867 0.991 PPARG FABP4 4436745 4434459 9606.ENSP00000287820 9606.ENSP00000256104 0 0 0 0 0.087 0.064 0.900 0.915 0.991 ESR1 SRC 4448358 4444215 9606.ENSP00000405330 9606.ENSP00000362680 0 0 0 0 0.061 0.520 0.900 0.803 0.990 AR SRC 4444436 4444215 9606.ENSP00000363822 9606.ENSP00000362680 0 0 0 0 0 0.407 0.900 0.857 0.990 CASP3 MAPK14 4438651 4433482 9606.ENSP00000311032 9606.ENSP00000229795 0 0 0 0 0.061 0.521 0.900 0.793 0.989 CCNA2 KIF11 4436109 4434801 9606.ENSP00000274026 9606.ENSP00000260731 0 0 0 0 0.977 0.150 0 0.478 0.989 HSP90AA1 EGFR 4440643 4436186 9606.ENSP00000335153 9606.ENSP00000275493 0 0 0 0 0 0.487 0.900 0.817 0.989 APAF1 XIAP 4450251 4443692 9606.ENSP00000448165 9606.ENSP00000360242 0 0 0 0 0.114 0.524 0.900 0.771 0.989 CDC42 SRC 4446990 4444215 9606.ENSP00000383118 9606.ENSP00000362680 0 0 0 0 0.066 0.160 0.900 0.864 0.988 AR HSP90AA1 4444436 4440643 9606.ENSP00000363822 9606.ENSP00000335153 0 0 0 0 0 0.474 0.900 0.803 0.988 AKT1 RHOA 4450372 4448110 9606.ENSP00000451828 9606.ENSP00000400175 0 0 0 0 0.061 0.160 0.900 0.858 0.987 NR1H3 RXRA 4451232 4449061 9606.ENSP00000477707 9606.ENSP00000419692 0 0 0 0.684 0.062 0.825 0.900 0.729 0.986 CCNA2 AURKA 4436109 4432988 9606.ENSP00000274026 9606.ENSP00000216911 0 0 0 0 0.964 0.177 0 0.582 0.986 RXRA NR1H2 4449061 4434320 9606.ENSP00000419692 9606.ENSP00000253727 0 0 0 0.694 0.061 0.825 0.900 0.713 0.985 HSP90AA1 PGR 4440643 4439740 9606.ENSP00000335153 9606.ENSP00000325120 0 0 0 0 0 0.523 0.900 0.720 0.985 TGFBR1 TGFB2 4444485 4442765 9606.ENSP00000364133 9606.ENSP00000355896 0 0 0 0 0.056 0.497 0.900 0.717 0.984 SERPINA1 ALB 4448813 4437206 9606.ENSP00000416066 9606.ENSP00000295897 0 0 0 0 0.292 0 0.900 0.789 0.983 DHFR SHMT1 4447922 4439233 9606.ENSP00000396308 9606.ENSP00000318868 0.071 0 0 0 0.173 0 0.900 0.813 0.983 HSP90AA1 NR3C1 4440643 4433539 9606.ENSP00000335153 9606.ENSP00000231509 0 0 0 0 0 0.474 0.900 0.710 0.983 HRAS PTPN11 4448459 4441096 9606.ENSP00000407586 9606.ENSP00000340944 0 0 0 0 0.086 0.186 0.900 0.790 0.982 SRC HSP90AA1 4444215 4440643 9606.ENSP00000362680 9606.ENSP00000335153 0 0 0 0 0 0.473 0.900 0.676 0.981 PTPN11 MAP2K1 4441096 4437859 9606.ENSP00000340944 9606.ENSP00000302486 0 0 0 0 0.064 0.468 0.900 0.667 0.981 CCNA2 CDK7 4436109 4434485 9606.ENSP00000274026 9606.ENSP00000256443 0 0.003 0 0 0.081 0.451 0.900 0.669 0.981 AKT1 RAC1 4450372 4441834 9606.ENSP00000451828 9606.ENSP00000348461 0 0 0 0 0.063 0.456 0.900 0.687 0.981 HRAS JAK2 4448459 4445579 9606.ENSP00000407586 9606.ENSP00000371067 0 0 0 0 0.055 0.160 0.900 0.790 0.981 HSP90AA1 KDR 4440643 4435337 9606.ENSP00000335153 9606.ENSP00000263923 0 0 0 0 0 0.391 0.900 0.710 0.980 RHOA SRC 4448110 4444215 9606.ENSP00000400175 9606.ENSP00000362680 0 0 0 0 0.084 0.160 0.900 0.772 0.980 ESR1 HSP90AA1 4448358 4440643 9606.ENSP00000405330 9606.ENSP00000335153 0 0 0 0 0 0.474 0.900 0.633 0.979 MAP2K1 MAPK14 4437859 4433482 9606.ENSP00000302486 9606.ENSP00000229795 0 0 0.364 0.632 0.064 0.676 0.900 0.788 0.979 SRC MMP9 4444215 4443919 9606.ENSP00000362680 9606.ENSP00000361405 0 0 0 0 0.088 0 0.900 0.796 0.979 AKT1 SRC 4450372 4444215 9606.ENSP00000451828 9606.ENSP00000362680 0 0 0.391 0.562 0.097 0.546 0.900 0.960 0.978 HDAC8 KAT2B 4444214 4435311 9606.ENSP00000362674 9606.ENSP00000263754 0 0 0 0 0.094 0.266 0.900 0.708 0.978 AKT1 IL2 4450372 4433376 9606.ENSP00000451828 9606.ENSP00000226730 0 0 0 0 0 0 0.900 0.793 0.978 ELANE RNASE3 4450799 4437847 9606.ENSP00000466090 9606.ENSP00000302324 0 0 0 0 0.557 0 0.900 0.542 0.977 GPI GCK 4448366 4433282 9606.ENSP00000405573 9606.ENSP00000223366 0 0 0 0 0.146 0 0.900 0.749 0.976 HRAS KIT 4448459 4436763 9606.ENSP00000407586 9606.ENSP00000288135 0 0 0 0 0 0.082 0.900 0.763 0.976 AKT1 PTPN11 4450372 4441096 9606.ENSP00000451828 9606.ENSP00000340944 0 0 0 0 0.088 0.160 0.900 0.727 0.976 MAPK8 IL2 4446429 4433376 9606.ENSP00000378974 9606.ENSP00000226730 0 0 0 0 0 0 0.900 0.769 0.975 HRAS FGFR1 4448459 4447790 9606.ENSP00000407586 9606.ENSP00000393312 0 0 0 0 0.064 0.186 0.900 0.716 0.975 CDK2 CDK6 4435732 4435642 9606.ENSP00000266970 9606.ENSP00000265734 0 0 0.439 0.927 0.108 0.711 0.900 0.908 0.974 HRAS MET 4448459 4439114 9606.ENSP00000407586 9606.ENSP00000317272 0 0 0 0 0 0.271 0.900 0.672 0.974 SRC NOS2 4444215 4439909 9606.ENSP00000362680 9606.ENSP00000327251 0 0 0 0 0.064 0.394 0.900 0.600 0.974 SRC MMP2 4444215 4433061 9606.ENSP00000362680 9606.ENSP00000219070 0 0 0 0 0.055 0 0.900 0.748 0.974 PTPN11 KIT 4441096 4436763 9606.ENSP00000340944 9606.ENSP00000288135 0 0 0 0 0.063 0.435 0.900 0.574 0.974 AKT1 APAF1 4450372 4450251 9606.ENSP00000451828 9606.ENSP00000448165 0 0 0 0 0.050 0.087 0.900 0.743 0.974 AKT1 SOD2 4450372 4450194 9606.ENSP00000451828 9606.ENSP00000446252 0 0 0 0 0 0 0.900 0.745 0.973 SRC PGR 4444215 4439740 9606.ENSP00000362680 9606.ENSP00000325120 0 0 0 0 0.062 0.407 0.900 0.560 0.972 CDC42 EGFR 4446990 4436186 9606.ENSP00000383118 9606.ENSP00000275493 0 0 0 0 0 0.126 0.900 0.714 0.972 PTPN11 MET 4441096 4439114 9606.ENSP00000340944 9606.ENSP00000317272 0 0 0 0 0.062 0.472 0.900 0.488 0.971 RXRA THRA 4449061 4435461 9606.ENSP00000419692 9606.ENSP00000264637 0 0 0 0.702 0.062 0.828 0.800 0.601 0.971 ERBB4 ADAM17 4441238 4438549 9606.ENSP00000342235 9606.ENSP00000309968 0 0 0 0 0 0.379 0.900 0.570 0.971 RHOA TGFBR1 4448110 4444485 9606.ENSP00000400175 9606.ENSP00000364133 0 0 0 0 0.051 0.208 0.900 0.639 0.969 MAPK8 RAC1 4446429 4441834 9606.ENSP00000378974 9606.ENSP00000348461 0 0 0 0 0.063 0.430 0.900 0.497 0.969 AKT1 CASP3 4450372 4438651 9606.ENSP00000451828 9606.ENSP00000311032 0 0 0 0 0.055 0.393 0 0.950 0.969 RHOA PTPN11 4448110 4441096 9606.ENSP00000400175 9606.ENSP00000340944 0 0 0 0 0.061 0.078 0.900 0.685 0.969 AR CDK6 4444436 4435642 9606.ENSP00000363822 9606.ENSP00000265734 0 0 0 0 0 0.524 0.900 0.399 0.968 RHOA EGFR 4448110 4436186 9606.ENSP00000400175 9606.ENSP00000275493 0 0 0 0 0 0.126 0.900 0.668 0.968 PTPN11 KDR 4441096 4435337 9606.ENSP00000340944 9606.ENSP00000263923 0 0 0 0 0.063 0.435 0.900 0.480 0.968 SRC PTPN11 4444215 4441096 9606.ENSP00000362680 9606.ENSP00000340944 0 0 0 0.550 0.063 0.469 0.900 0.930 0.968 PTPN11 IL2 4441096 4433376 9606.ENSP00000340944 9606.ENSP00000226730 0 0 0 0 0 0 0.900 0.694 0.968 ELANE MMP8 4450799 4433667 9606.ENSP00000466090 9606.ENSP00000236826 0 0 0 0 0.175 0 0.900 0.633 0.967 AR KAT2B 4444436 4435311 9606.ENSP00000363822 9606.ENSP00000263754 0 0 0 0 0 0.478 0.900 0.430 0.967 NR3C2 HSP90AA1 4442077 4440643 9606.ENSP00000350815 9606.ENSP00000335153 0 0 0 0 0 0.474 0.900 0.425 0.967 AR GSK3B 4444436 4439717 9606.ENSP00000363822 9606.ENSP00000324806 0 0 0 0 0 0.407 0.900 0.490 0.967 IMPDH2 ATIC 4439459 4433672 9606.ENSP00000321584 9606.ENSP00000236959 0.167 0 0 0 0.398 0 0.900 0.419 0.966 SRC ESR2 4444215 4441379 9606.ENSP00000362680 9606.ENSP00000343925 0 0 0 0 0 0.407 0.900 0.459 0.965 MAPK8 NR3C1 4446429 4433539 9606.ENSP00000378974 9606.ENSP00000231509 0 0 0 0 0.054 0.379 0.900 0.476 0.965 HRAS IL2 4448459 4433376 9606.ENSP00000407586 9606.ENSP00000226730 0 0 0 0 0 0 0.900 0.671 0.965 HRAS MAPK8 4448459 4446429 9606.ENSP00000407586 9606.ENSP00000378974 0 0 0 0 0.055 0.459 0.800 0.703 0.965 F7 F10 4444589 4444587 9606.ENSP00000364731 9606.ENSP00000364709 0 0 0.423 0.897 0.404 0.379 0.900 0.786 0.964 MMP9 MMP8 4443919 4433667 9606.ENSP00000361405 9606.ENSP00000236826 0 0 0 0.738 0.546 0 0.900 0.915 0.964 ESR1 PGR 4448358 4439740 9606.ENSP00000405330 9606.ENSP00000325120 0 0 0 0.679 0.102 0.472 0.900 0.964 0.964 SRC RAC1 4444215 4441834 9606.ENSP00000362680 9606.ENSP00000348461 0 0 0 0 0 0.160 0.900 0.607 0.964 BTK SYK 4451790 4444619 9606.ENSP00000483570 9606.ENSP00000364907 0 0 0 0.656 0.305 0.321 0.900 0.907 0.964 HRAS HSP90AA1 4448459 4440643 9606.ENSP00000407586 9606.ENSP00000335153 0 0 0 0 0.055 0.052 0.900 0.640 0.963 PNP DCK 4442485 4436686 9606.ENSP00000354532 9606.ENSP00000286648 0 0 0 0 0 0 0.900 0.647 0.963 CDC42 ABL1 4446990 4443923 9606.ENSP00000383118 9606.ENSP00000361423 0 0 0 0 0 0.160 0.900 0.600 0.963 SRC EGFR 4444215 4436186 9606.ENSP00000362680 9606.ENSP00000275493 0 0 0 0.671 0 0.484 0.900 0.954 0.963 HRAS INSR 4448459 4437994 9606.ENSP00000407586 9606.ENSP00000303830 0 0 0 0 0 0.456 0.900 0.357 0.962 ESR1 MAPK14 4448358 4433482 9606.ENSP00000405330 9606.ENSP00000229795 0 0 0 0 0 0.399 0.900 0.421 0.962 CHEK1 CDK2 4447561 4435732 9606.ENSP00000388648 9606.ENSP00000266970 0 0 0.308 0.719 0.325 0.261 0.900 0.885 0.962 F2 ALB 4438421 4437206 9606.ENSP00000308541 9606.ENSP00000295897 0 0 0 0 0.624 0.043 0 0.897 0.960 MAP2K1 IL2 4437859 4433376 9606.ENSP00000302486 9606.ENSP00000226730 0 0 0 0 0 0 0.900 0.625 0.960 SRC KDR 4444215 4435337 9606.ENSP00000362680 9606.ENSP00000263923 0 0 0 0.651 0.058 0.460 0.900 0.843 0.960 DHFR ATIC 4447922 4433672 9606.ENSP00000396308 9606.ENSP00000236959 0.044 0 0 0 0.097 0.050 0.900 0.594 0.960 JAK2 KIT 4445579 4436763 9606.ENSP00000371067 9606.ENSP00000288135 0 0 0 0.563 0 0.472 0.900 0.669 0.960 ESR2 HSP90AA1 4441379 4440643 9606.ENSP00000343925 9606.ENSP00000335153 0 0 0 0 0 0.474 0.900 0.293 0.959 MMP9 MMP3 4443919 4437610 9606.ENSP00000361405 9606.ENSP00000299855 0 0 0 0.791 0.518 0 0.900 0.911 0.959 CDC42 MAPK14 4446990 4433482 9606.ENSP00000383118 9606.ENSP00000229795 0 0 0 0 0.061 0.185 0.900 0.537 0.959 HSPA8 EGFR 4449616 4436186 9606.ENSP00000432083 9606.ENSP00000275493 0 0 0 0 0 0.393 0.900 0.386 0.959 JAK2 SRC 4445579 4444215 9606.ENSP00000371067 9606.ENSP00000362680 0 0 0 0.636 0.061 0.421 0.900 0.851 0.959 SRC F2 4444215 4438421 9606.ENSP00000362680 9606.ENSP00000308541 0 0 0 0 0 0.050 0.900 0.608 0.959 AKT1 RARA 4450372 4434338 9606.ENSP00000451828 9606.ENSP00000254066 0 0 0 0 0.088 0.407 0.900 0.325 0.958 CDK6 CDK7 4435642 4434485 9606.ENSP00000265734 9606.ENSP00000256443 0 0 0.393 0.846 0.063 0.504 0.900 0.805 0.958 CTSK MMP13 4435989 4434767 9606.ENSP00000271651 9606.ENSP00000260302 0 0 0 0 0.062 0 0.900 0.591 0.958 CDK2 CDK7 4435732 4434485 9606.ENSP00000266970 9606.ENSP00000256443 0 0 0.408 0.926 0.067 0.539 0.900 0.920 0.957 CDC42 SYK 4446990 4444619 9606.ENSP00000383118 9606.ENSP00000364907 0 0 0 0 0.064 0.160 0.900 0.513 0.956 PTPN11 INSR 4441096 4437994 9606.ENSP00000340944 9606.ENSP00000303830 0 0 0 0 0.062 0.456 0.900 0.247 0.956 HSD17B1 SULT1E1 4450822 4433371 9606.ENSP00000466799 9606.ENSP00000226444 0 0 0 0 0.060 0 0.900 0.571 0.956 CDC42 MET 4446990 4439114 9606.ENSP00000383118 9606.ENSP00000317272 0 0 0 0 0.063 0.271 0.900 0.429 0.955 KAT2B RARA 4435311 4434338 9606.ENSP00000263754 9606.ENSP00000254066 0 0 0 0 0 0.478 0.900 0.217 0.955 SHMT1 SDS 4439233 4434551 9606.ENSP00000318868 9606.ENSP00000257549 0 0 0 0 0.063 0 0.900 0.559 0.955 RXRA PPARD 4449061 4438644 9606.ENSP00000419692 9606.ENSP00000310928 0 0 0 0.705 0.062 0.467 0.900 0.604 0.955 RAC1 MAP2K1 4441834 4437859 9606.ENSP00000348461 9606.ENSP00000302486 0 0 0 0 0.061 0.185 0.900 0.490 0.955 VDR RXRA 4450226 4449061 9606.ENSP00000447173 9606.ENSP00000419692 0 0 0 0.635 0 0.438 0.900 0.677 0.955 TEK PTPN11 4445310 4441096 9606.ENSP00000369375 9606.ENSP00000340944 0 0 0 0 0.063 0.400 0.900 0.295 0.955 CDC42 KDR 4446990 4435337 9606.ENSP00000383118 9606.ENSP00000263923 0 0 0 0 0 0.182 0.900 0.501 0.955 HSP90AA1 RAB11A 4440643 4434975 9606.ENSP00000335153 9606.ENSP00000261890 0 0 0 0 0 0.052 0.900 0.568 0.955 RHOA CASP3 4448110 4438651 9606.ENSP00000400175 9606.ENSP00000311032 0 0 0 0 0.058 0.054 0.900 0.555 0.955 MMP3 EGFR 4437610 4436186 9606.ENSP00000299855 9606.ENSP00000275493 0 0 0 0 0.076 0 0.900 0.543 0.954 MAPK8 SRC 4446429 4444215 9606.ENSP00000378974 9606.ENSP00000362680 0 0 0.376 0.573 0.063 0.166 0.900 0.866 0.954 SRC MET 4444215 4439114 9606.ENSP00000362680 9606.ENSP00000317272 0 0 0 0.684 0.063 0.407 0.900 0.795 0.954 RHOA MET 4448110 4439114 9606.ENSP00000400175 9606.ENSP00000317272 0 0 0 0 0 0.271 0.900 0.421 0.954 SYK IL2 4444619 4433376 9606.ENSP00000364907 9606.ENSP00000226730 0 0 0 0 0 0 0.900 0.559 0.954 JAK2 IL2 4445579 4433376 9606.ENSP00000371067 9606.ENSP00000226730 0 0 0 0 0 0 0.900 0.561 0.954 GSK3B AURKA 4439717 4432988 9606.ENSP00000324806 9606.ENSP00000216911 0 0 0.326 0.624 0 0.394 0.900 0.485 0.953 CASP3 BIRC7 4438651 4433001 9606.ENSP00000311032 9606.ENSP00000217169 0 0 0 0 0.056 0.469 0.800 0.590 0.953 CHEK1 CCNA2 4447561 4436109 9606.ENSP00000388648 9606.ENSP00000274026 0 0 0 0 0.853 0.064 0 0.685 0.953 SYK SRC 4444619 4444215 9606.ENSP00000364907 9606.ENSP00000362680 0 0 0 0.729 0.054 0.393 0.900 0.913 0.953 NR1H4 ALB 4450225 4437206 9606.ENSP00000447149 9606.ENSP00000295897 0 0 0 0 0.232 0.074 0.900 0.420 0.953 CDC42 MAPK10 4446990 4442217 9606.ENSP00000383118 9606.ENSP00000352157 0 0 0 0 0.063 0.162 0.900 0.476 0.953 TGFBR1 XIAP 4444485 4443692 9606.ENSP00000364133 9606.ENSP00000360242 0 0 0 0 0.062 0.470 0.900 0.170 0.953 SRC MAP2K1 4444215 4437859 9606.ENSP00000362680 9606.ENSP00000302486 0 0 0.215 0.589 0.062 0.308 0.900 0.730 0.953 CRABP2 RARA 4451723 4434338 9606.ENSP00000482841 9606.ENSP00000254066 0 0 0 0 0 0.064 0.900 0.530 0.952 PLAU F2 4444017 4438421 9606.ENSP00000361850 9606.ENSP00000308541 0 0 0.415 0.645 0 0.379 0.900 0.434 0.952 RHOA KDR 4448110 4435337 9606.ENSP00000400175 9606.ENSP00000263923 0 0 0 0 0 0.080 0.900 0.528 0.952 DHFR AKR1B1 4447922 4436650 9606.ENSP00000396308 9606.ENSP00000285930 0 0 0 0 0 0 0.900 0.534 0.951 PLAU EGFR 4444017 4436186 9606.ENSP00000361850 9606.ENSP00000275493 0 0 0 0 0.088 0 0.900 0.513 0.951 BTK HRAS 4451790 4448459 9606.ENSP00000483570 9606.ENSP00000407586 0 0 0 0 0.061 0.160 0.900 0.451 0.950 HRAS AR 4448459 4444436 9606.ENSP00000407586 9606.ENSP00000363822 0 0 0 0 0 0.084 0.900 0.498 0.950 TEK MMP2 4445310 4433061 9606.ENSP00000369375 9606.ENSP00000219070 0 0 0 0 0.142 0 0.900 0.472 0.950 RARA NR3C1 4434338 4433539 9606.ENSP00000254066 9606.ENSP00000231509 0 0 0 0.614 0 0.430 0.900 0.377 0.948 AKT1 INSR 4450372 4437994 9606.ENSP00000451828 9606.ENSP00000303830 0 0 0 0.559 0.052 0.288 0.900 0.677 0.948 RHOA SYK 4448110 4444619 9606.ENSP00000400175 9606.ENSP00000364907 0 0 0 0 0 0.160 0.900 0.441 0.948 ESR1 KAT2B 4448358 4435311 9606.ENSP00000405330 9606.ENSP00000263754 0 0 0 0 0 0.194 0.900 0.398 0.947 HSP90AA1 AURKA 4440643 4432988 9606.ENSP00000335153 9606.ENSP00000216911 0 0 0 0 0.072 0.092 0.900 0.444 0.946 EIF4E CASP3 4449328 4438651 9606.ENSP00000425561 9606.ENSP00000311032 0 0 0 0 0 0 0.900 0.489 0.946 RHOA CDK2 4448110 4435732 9606.ENSP00000400175 9606.ENSP00000266970 0 0 0 0 0.052 0.095 0.900 0.446 0.946 BTK CDC42 4451790 4446990 9606.ENSP00000483570 9606.ENSP00000383118 0 0 0 0 0.052 0.160 0.900 0.405 0.946 RAC1 EGFR 4441834 4436186 9606.ENSP00000348461 9606.ENSP00000275493 0 0 0 0 0 0.126 0.900 0.440 0.946 AR MAPK14 4444436 4433482 9606.ENSP00000363822 9606.ENSP00000229795 0 0 0 0 0 0.073 0.900 0.462 0.945 ELANE SERPINA1 4450799 4448813 9606.ENSP00000466090 9606.ENSP00000416066 0 0 0 0 0.073 0.447 0 0.901 0.945 KAT2B NR3C1 4435311 4433539 9606.ENSP00000263754 9606.ENSP00000231509 0 0 0 0 0.083 0.194 0.900 0.349 0.945 MAPK8 AR 4446429 4444436 9606.ENSP00000378974 9606.ENSP00000363822 0 0 0 0 0 0 0.900 0.479 0.945 RXRA FABP4 4449061 4434459 9606.ENSP00000419692 9606.ENSP00000256104 0 0 0 0 0.061 0.064 0.900 0.455 0.945 HSD11B1 PPARG 4442791 4436745 9606.ENSP00000355995 9606.ENSP00000287820 0 0 0 0 0.061 0 0.900 0.462 0.945 AR NR3C2 4444436 4442077 9606.ENSP00000363822 9606.ENSP00000350815 0 0 0 0.779 0.061 0.379 0.900 0.670 0.945 HSPA8 NR3C1 4449616 4433539 9606.ENSP00000432083 9606.ENSP00000231509 0 0 0 0 0 0.166 0.900 0.386 0.944 KAT2B MAPK14 4435311 4433482 9606.ENSP00000263754 9606.ENSP00000229795 0 0 0 0 0.055 0.342 0.900 0.214 0.944 SYK RAC1 4444619 4441834 9606.ENSP00000364907 9606.ENSP00000348461 0 0 0 0 0.064 0.160 0.900 0.381 0.944 SRC PLAU 4444215 4444017 9606.ENSP00000362680 9606.ENSP00000361850 0 0 0 0 0.069 0.050 0.900 0.443 0.944 AR NR3C1 4444436 4433539 9606.ENSP00000363822 9606.ENSP00000231509 0 0 0 0.816 0 0.379 0.900 0.806 0.944 MAPK8 MAPKAPK2 4446429 4442808 9606.ENSP00000378974 9606.ENSP00000356070 0 0 0.370 0.586 0 0.179 0.900 0.594 0.944 MAPKAPK2 MAPK10 4442808 4442217 9606.ENSP00000356070 9606.ENSP00000352157 0 0 0.303 0.583 0 0.179 0.900 0.628 0.943 SYK PTPN11 4444619 4441096 9606.ENSP00000364907 9606.ENSP00000340944 0 0 0 0.550 0.062 0.160 0.900 0.776 0.943 HRAS RAC1 4448459 4441834 9606.ENSP00000407586 9606.ENSP00000348461 0 0 0.254 0.750 0.064 0.348 0.900 0.432 0.943 ESR1 EGFR 4448358 4436186 9606.ENSP00000405330 9606.ENSP00000275493 0 0 0 0 0 0.402 0 0.908 0.943 GSK3B NR3C1 4439717 4433539 9606.ENSP00000324806 9606.ENSP00000231509 0 0 0 0 0 0.085 0.900 0.432 0.943 NR3C2 NR3C1 4442077 4433539 9606.ENSP00000350815 9606.ENSP00000231509 0 0 0 0.861 0 0.379 0.900 0.942 0.943 CDK7 RARA 4434485 4434338 9606.ENSP00000256443 9606.ENSP00000254066 0 0 0 0 0 0.320 0.900 0.234 0.943 MAPK8 MAPK14 4446429 4433482 9606.ENSP00000378974 9606.ENSP00000229795 0 0 0.396 0.924 0.064 0.386 0.900 0.937 0.943 SRC ABL1 4444215 4443923 9606.ENSP00000362680 9606.ENSP00000361423 0 0 0 0.882 0.067 0.379 0.900 0.922 0.943 CRABP2 RXRA 4451723 4449061 9606.ENSP00000482841 9606.ENSP00000419692 0 0 0 0 0 0.064 0.900 0.432 0.942 SRC MAPK14 4444215 4433482 9606.ENSP00000362680 9606.ENSP00000229795 0 0 0.254 0.627 0 0.146 0.900 0.765 0.941 ESR1 ESR2 4448358 4441379 9606.ENSP00000405330 9606.ENSP00000343925 0 0 0 0.925 0.061 0.379 0.900 0.967 0.941 MAPK14 IL2 4433482 4433376 9606.ENSP00000229795 9606.ENSP00000226730 0 0 0 0 0 0 0.900 0.440 0.941 RAC1 MAPK14 4441834 4433482 9606.ENSP00000348461 9606.ENSP00000229795 0 0 0 0 0.061 0.185 0.900 0.320 0.941 JAK2 MAP2K1 4445579 4437859 9606.ENSP00000371067 9606.ENSP00000302486 0 0 0 0.601 0 0.261 0.900 0.581 0.940 RHOA CDC42 4448110 4446990 9606.ENSP00000400175 9606.ENSP00000383118 0 0 0.418 0.950 0.267 0.186 0.900 0.960 0.939 BTK SRC 4451790 4444215 9606.ENSP00000483570 9606.ENSP00000362680 0 0 0 0.850 0.062 0.315 0.900 0.935 0.939 HSP90AA1 IL2 4440643 4433376 9606.ENSP00000335153 9606.ENSP00000226730 0 0 0 0 0 0 0.900 0.416 0.939 AKT1 CDC42 4450372 4446990 9606.ENSP00000451828 9606.ENSP00000383118 0 0 0 0 0.063 0.160 0 0.928 0.939 F10 F2 4444587 4438421 9606.ENSP00000364709 9606.ENSP00000308541 0 0 0.391 0.763 0.200 0 0.900 0.806 0.938 HSPA8 AR 4449616 4444436 9606.ENSP00000432083 9606.ENSP00000363822 0 0 0 0 0 0.109 0.900 0.348 0.936 RHOA HSP90AA1 4448110 4440643 9606.ENSP00000400175 9606.ENSP00000335153 0 0 0 0 0 0.052 0.900 0.387 0.936 AKT1 AURKA 4450372 4432988 9606.ENSP00000451828 9606.ENSP00000216911 0 0 0.351 0.723 0 0.161 0.900 0.739 0.936 JAK2 NOS2 4445579 4439909 9606.ENSP00000371067 9606.ENSP00000327251 0 0 0 0 0 0.065 0.900 0.364 0.935 ERBB4 EGFR 4441238 4436186 9606.ENSP00000342235 9606.ENSP00000275493 0 0 0 0.946 0 0.347 0.900 0.905 0.935 DAPK1 CASP3 4447310 4438651 9606.ENSP00000386135 9606.ENSP00000311032 0 0 0 0 0 0 0.900 0.384 0.935 RAC1 MET 4441834 4439114 9606.ENSP00000348461 9606.ENSP00000317272 0 0 0 0 0.061 0.271 0.900 0.171 0.935 ABL1 RAC1 4443923 4441834 9606.ENSP00000361423 9606.ENSP00000348461 0 0 0 0 0 0.160 0.900 0.292 0.935 HRAS RHOA 4448459 4448110 9606.ENSP00000407586 9606.ENSP00000400175 0 0 0.415 0.768 0.064 0.170 0.900 0.655 0.934 NR3C1 MAPK14 4433539 4433482 9606.ENSP00000231509 9606.ENSP00000229795 0 0 0 0 0 0.073 0.900 0.347 0.934 HRAS F2 4448459 4438421 9606.ENSP00000407586 9606.ENSP00000308541 0 0 0 0 0 0.050 0.900 0.357 0.933 RXRA KAT2B 4449061 4435311 9606.ENSP00000419692 9606.ENSP00000263754 0 0 0 0 0.061 0.194 0.900 0.222 0.933 EIF4E MAPK14 4449328 4433482 9606.ENSP00000425561 9606.ENSP00000229795 0 0 0 0 0.062 0 0.900 0.351 0.933 HRAS TEK 4448459 4445310 9606.ENSP00000407586 9606.ENSP00000369375 0 0 0 0 0 0.082 0.900 0.325 0.932 RHOA IL2 4448110 4433376 9606.ENSP00000400175 9606.ENSP00000226730 0 0 0 0 0 0 0.900 0.348 0.932 CDK2 AURKA 4435732 4432988 9606.ENSP00000266970 9606.ENSP00000216911 0 0 0.431 0.760 0.303 0.880 0 0.587 0.932 AKT1 AR 4450372 4444436 9606.ENSP00000451828 9606.ENSP00000363822 0 0 0 0 0 0.407 0 0.890 0.932 BTK RAC1 4451790 4441834 9606.ENSP00000483570 9606.ENSP00000348461 0 0 0 0 0.093 0.160 0.900 0.213 0.932 AKT1 MAPK14 4450372 4433482 9606.ENSP00000451828 9606.ENSP00000229795 0 0 0.303 0.623 0.082 0.715 0.600 0.858 0.931 HSPA8 PGR 4449616 4439740 9606.ENSP00000432083 9606.ENSP00000325120 0 0 0 0 0 0.183 0.900 0.229 0.931 ABL1 CCNA2 4443923 4436109 9606.ENSP00000361423 9606.ENSP00000274026 0 0 0 0 0 0.090 0.900 0.297 0.930 ALB TTR 4437206 4433675 9606.ENSP00000295897 9606.ENSP00000237014 0 0 0 0 0.295 0.104 0 0.898 0.930 AKT1 RXRA 4450372 4449061 9606.ENSP00000451828 9606.ENSP00000419692 0 0 0 0 0.085 0.085 0.900 0.271 0.930 SYK MAPK14 4444619 4433482 9606.ENSP00000364907 9606.ENSP00000229795 0 0 0 0.574 0.061 0.146 0.900 0.507 0.930 ABL1 CDK6 4443923 4435642 9606.ENSP00000361423 9606.ENSP00000265734 0 0 0 0.616 0.062 0.093 0.900 0.628 0.929 ABL1 CDK2 4443923 4435732 9606.ENSP00000361423 9606.ENSP00000266970 0 0 0 0.658 0.085 0.149 0.900 0.494 0.929 MME DPP4 4448967 4442387 9606.ENSP00000418525 9606.ENSP00000353731 0 0 0 0 0.075 0 0.800 0.643 0.928 JAK2 EGFR 4445579 4436186 9606.ENSP00000371067 9606.ENSP00000275493 0 0 0 0.573 0 0.472 0.800 0.830 0.928 CASP1 CASP3 4449658 4438651 9606.ENSP00000433138 9606.ENSP00000311032 0 0 0 0.658 0 0 0.900 0.831 0.928 HRAS PIM1 4448459 4444200 9606.ENSP00000407586 9606.ENSP00000362608 0 0 0 0 0.061 0.157 0.900 0.198 0.928 BTK MAPK8 4451790 4446429 9606.ENSP00000483570 9606.ENSP00000378974 0 0 0 0.568 0.061 0.115 0.900 0.480 0.927 MAPK10 RAC1 4442217 4441834 9606.ENSP00000352157 9606.ENSP00000348461 0 0 0 0 0.063 0.162 0.900 0.169 0.926 JAK2 CDK6 4445579 4435642 9606.ENSP00000371067 9606.ENSP00000265734 0 0 0 0.640 0.062 0.175 0.900 0.372 0.926 JAK2 ERBB4 4445579 4441238 9606.ENSP00000371067 9606.ENSP00000342235 0 0 0 0.576 0 0.102 0.900 0.520 0.926 RAC1 KDR 4441834 4435337 9606.ENSP00000348461 9606.ENSP00000263923 0 0 0 0 0 0.131 0.900 0.224 0.926 CHEK1 CDK7 4447561 4434485 9606.ENSP00000388648 9606.ENSP00000256443 0 0 0.310 0.642 0.062 0 0.900 0.493 0.926 CASP1 RHOA 4449658 4448110 9606.ENSP00000433138 9606.ENSP00000400175 0 0 0 0 0 0.054 0.900 0.283 0.926 RHOA FKBP1A 4448110 4446979 9606.ENSP00000400175 9606.ENSP00000383003 0 0 0 0 0.136 0 0.900 0.204 0.925 MAPK8 ABL1 4446429 4443923 9606.ENSP00000378974 9606.ENSP00000361423 0 0 0 0.580 0 0.073 0.900 0.568 0.925 MAPK8 MAP2K1 4446429 4437859 9606.ENSP00000378974 9606.ENSP00000302486 0 0 0.361 0.591 0.063 0.348 0.800 0.862 0.925 MMP16 MMP2 4436682 4433061 9606.ENSP00000286614 9606.ENSP00000219070 0 0 0 0.768 0.098 0 0.900 0.879 0.925 ESR1 NR3C1 4448358 4433539 9606.ENSP00000405330 9606.ENSP00000231509 0 0 0 0.660 0 0 0.900 0.751 0.925 ABL1 MAPK14 4443923 4433482 9606.ENSP00000361423 9606.ENSP00000229795 0 0 0 0.623 0.061 0.146 0.900 0.384 0.924 RHOA RAC1 4448110 4441834 9606.ENSP00000400175 9606.ENSP00000348461 0 0 0.408 0.945 0.113 0.157 0.900 0.777 0.923 MAPK8 MET 4446429 4439114 9606.ENSP00000378974 9606.ENSP00000317272 0 0 0 0.560 0.062 0.073 0.900 0.447 0.923 RXRA MAPK8 4449061 4446429 9606.ENSP00000419692 9606.ENSP00000378974 0 0 0 0 0 0 0.900 0.262 0.923 RXRA NR3C1 4449061 4433539 9606.ENSP00000419692 9606.ENSP00000231509 0 0 0 0.632 0 0 0.900 0.641 0.923 MMP3 MMP2 4437610 4433061 9606.ENSP00000299855 9606.ENSP00000219070 0 0 0 0.880 0.181 0 0.900 0.892 0.923 GSK3B CDK6 4439717 4435642 9606.ENSP00000324806 9606.ENSP00000265734 0 0 0.304 0.730 0.063 0.093 0.900 0.386 0.922 MAPK8 KIT 4446429 4436763 9606.ENSP00000378974 9606.ENSP00000288135 0 0 0 0.566 0 0.087 0.900 0.447 0.922 TGFB2 ALB 4442765 4437206 9606.ENSP00000355896 9606.ENSP00000295897 0 0 0 0 0 0 0.900 0.255 0.922 HSP90AA1 MMP2 4440643 4433061 9606.ENSP00000335153 9606.ENSP00000219070 0 0 0 0 0 0.379 0 0.878 0.921 KDR MAPK14 4435337 4433482 9606.ENSP00000263923 9606.ENSP00000229795 0 0 0 0.579 0 0.084 0.900 0.442 0.921 CDC42 MAPKAPK2 4446990 4442808 9606.ENSP00000383118 9606.ENSP00000356070 0 0 0 0 0.063 0 0.900 0.220 0.920 AR PGR 4444436 4439740 9606.ENSP00000363822 9606.ENSP00000325120 0 0 0 0.813 0.069 0 0.900 0.904 0.919 MMP9 MMP13 4443919 4434767 9606.ENSP00000361405 9606.ENSP00000260302 0 0 0 0.797 0.064 0 0.900 0.878 0.919 BTK JAK2 4451790 4445579 9606.ENSP00000483570 9606.ENSP00000371067 0 0 0 0.618 0.080 0 0.900 0.448 0.919 ELANE TTR 4450799 4433675 9606.ENSP00000466090 9606.ENSP00000237014 0 0 0 0 0.062 0 0.900 0.211 0.919 HSPA8 NR3C2 4449616 4442077 9606.ENSP00000432083 9606.ENSP00000350815 0 0 0 0 0 0.109 0.900 0.163 0.919 RAC1 HSP90AA1 4441834 4440643 9606.ENSP00000348461 9606.ENSP00000335153 0 0 0 0 0 0.052 0.900 0.208 0.918 CASP1 EIF4E 4449658 4449328 9606.ENSP00000433138 9606.ENSP00000425561 0 0 0 0 0 0 0.900 0.219 0.918 MAPK8 RARA 4446429 4434338 9606.ENSP00000378974 9606.ENSP00000254066 0 0 0 0 0 0 0.900 0.218 0.918 MAPK8 TEK 4446429 4445310 9606.ENSP00000378974 9606.ENSP00000369375 0 0 0 0.566 0 0.087 0.900 0.328 0.917 RXRA NR1I2 4449061 4440710 9606.ENSP00000419692 9606.ENSP00000336528 0 0 0 0.631 0.061 0.890 0 0.639 0.917 RXRA ALB 4449061 4437206 9606.ENSP00000419692 9606.ENSP00000295897 0 0 0 0 0.062 0.074 0.900 0.167 0.917 SOD2 GSR 4450194 4433142 9606.ENSP00000446252 9606.ENSP00000221130 0.071 0 0 0 0.113 0 0 0.906 0.916 F2 MAP2K1 4438421 4437859 9606.ENSP00000308541 9606.ENSP00000302486 0 0 0 0 0 0 0.900 0.189 0.915 MAPK10 NR3C1 4442217 4433539 9606.ENSP00000352157 9606.ENSP00000231509 0 0 0 0 0.051 0 0.900 0.179 0.915 VDR RARA 4450226 4434338 9606.ENSP00000447173 9606.ENSP00000254066 0 0 0 0.697 0 0 0.900 0.497 0.914 RAC1 KIT 4441834 4436763 9606.ENSP00000348461 9606.ENSP00000288135 0 0 0 0 0 0.080 0.900 0.144 0.914 NR3C2 PGR 4442077 4439740 9606.ENSP00000350815 9606.ENSP00000325120 0 0 0 0.809 0.061 0 0.900 0.663 0.914 AKT1 XIAP 4450372 4443692 9606.ENSP00000451828 9606.ENSP00000360242 0 0 0 0 0 0.704 0 0.721 0.913 CHEK1 KIT 4447561 4436763 9606.ENSP00000388648 9606.ENSP00000288135 0 0 0 0.554 0 0.057 0.900 0.296 0.913 TEK MAPK14 4445310 4433482 9606.ENSP00000369375 9606.ENSP00000229795 0 0 0 0.585 0 0.084 0.900 0.257 0.913 THRA RARA 4435461 4434338 9606.ENSP00000264637 9606.ENSP00000254066 0 0 0 0.795 0.070 0 0.900 0.555 0.913 PGR NR3C1 4439740 4433539 9606.ENSP00000325120 9606.ENSP00000231509 0 0 0 0.839 0 0 0.900 0.780 0.912 PDE4D DCK 4441530 4436686 9606.ENSP00000345502 9606.ENSP00000286648 0 0 0 0 0.061 0 0.900 0.140 0.912 MMP13 MMP2 4434767 4433061 9606.ENSP00000260302 9606.ENSP00000219070 0 0 0 0.890 0.061 0 0.900 0.835 0.911 MMP3 MMP13 4437610 4434767 9606.ENSP00000299855 9606.ENSP00000260302 0 0 0.249 0.944 0.085 0 0.900 0.893 0.910 MAPK10 MAPK14 4442217 4433482 9606.ENSP00000352157 9606.ENSP00000229795 0 0 0.347 0.921 0.064 0.052 0.900 0.594 0.910 MMP16 MMP13 4436682 4434767 9606.ENSP00000286614 9606.ENSP00000260302 0 0 0 0.859 0 0 0.900 0.741 0.910 AKT1 NOS2 4450372 4439909 9606.ENSP00000451828 9606.ENSP00000327251 0 0 0 0 0.063 0.065 0.800 0.543 0.909 RXRA NOS2 4449061 4439909 9606.ENSP00000419692 9606.ENSP00000327251 0 0 0 0 0 0.091 0.900 0.087 0.909 MAPKAPK2 KDR 4442808 4435337 9606.ENSP00000356070 9606.ENSP00000263923 0 0 0 0.559 0 0 0.900 0.217 0.908 ESR1 MAPK8 4448358 4446429 9606.ENSP00000405330 9606.ENSP00000378974 0 0 0 0 0 0 0.800 0.559 0.908 HRAS MAPK10 4448459 4442217 9606.ENSP00000407586 9606.ENSP00000352157 0 0 0 0 0.055 0.166 0.800 0.487 0.908 MMP9 MMP2 4443919 4433061 9606.ENSP00000361405 9606.ENSP00000219070 0 0 0 0.929 0.061 0 0.900 0.958 0.908 RARA MAPK14 4434338 4433482 9606.ENSP00000254066 9606.ENSP00000229795 0 0 0 0 0 0.073 0.900 0.081 0.907 VDR GC 4450226 4449184 9606.ENSP00000447173 9606.ENSP00000421725 0 0 0 0 0.062 0.057 0 0.902 0.906 CDC42 RAC1 4446990 4441834 9606.ENSP00000383118 9606.ENSP00000348461 0 0 0.442 0.970 0.072 0 0.900 0.763 0.906 SERPINA1 TGFB2 4448813 4442765 9606.ENSP00000416066 9606.ENSP00000355896 0 0 0 0 0 0 0.900 0.107 0.906 RXRA HSD11B1 4449061 4442791 9606.ENSP00000419692 9606.ENSP00000355995 0 0 0 0 0 0 0.900 0.094 0.905 ERBB4 PTPN11 4441238 4441096 9606.ENSP00000342235 9606.ENSP00000340944 0 0 0 0 0 0.800 0 0.547 0.905 RNASE3 TTR 4437847 4433675 9606.ENSP00000302324 9606.ENSP00000237014 0 0 0 0 0 0 0.900 0.087 0.904 NR1H3 NR1H2 4451232 4434320 9606.ENSP00000477707 9606.ENSP00000253727 0 0 0 0.960 0 0 0.900 0.855 0.903 MAPK8 MAPK10 4446429 4442217 9606.ENSP00000378974 9606.ENSP00000352157 0 0 0.445 0.984 0.061 0 0.900 0.741 0.903 PDE4B DCK 4440326 4436686 9606.ENSP00000332116 9606.ENSP00000286648 0 0 0 0 0.061 0 0.900 0 0.902 AKT1 HRAS 4450372 4448459 9606.ENSP00000451828 9606.ENSP00000407586 0 0 0 0 0.076 0.160 0 0.883 0.901 MAPK8 CASP3 4446429 4438651 9606.ENSP00000378974 9606.ENSP00000311032 0 0 0 0 0.055 0.294 0 0.863 0.901