KEGG Pathway Term ID KEGG Pathway Term Desc KEGG Pathway Term Level1 KEGG Pathway Term Level2 Term Candidate Gene Num Total Candidate Gene Num Term Gene Num Total Gene Num Rich Ratio P value Q value 4510 Focal adhesion Cellular Processes Cellular community - eukaryotes 153 3760 217 8888 0.705069124 1.79E-17 5.24E-15 4141 Protein processing in endoplasmic reticulum Genetic Information Processing "Folding, sorting and degradation" 131 3760 184 8888 0.711956522 1.12E-15 3.26E-13 4110 Cell cycle Cellular Processes Cell growth and death 101 3760 133 8888 0.759398496 2.04E-15 5.95E-13 4218 Cellular senescence Cellular Processes Cell growth and death 139 3760 203 8888 0.684729064 2.47E-14 7.22E-12 4144 Endocytosis Cellular Processes Transport and catabolism 194 3760 311 8888 0.623794212 3.32E-13 9.69E-11 4360 Axon guidance Organismal Systems Development 127 3760 187 8888 0.679144385 8.37E-13 2.44E-10 4151 PI3K-Akt signaling pathway Environmental Information Processing Signal transduction 235 3760 396 8888 0.593434343 2.29E-12 6.67E-10 1100 Metabolic pathways Metabolism Global and overview maps 741 3760 1470 8888 0.504081633 4.47E-12 1.30E-09 4114 Oocyte meiosis Cellular Processes Cell growth and death 88 3760 122 8888 0.721311475 1.83E-11 5.35E-09 4120 Ubiquitin mediated proteolysis Genetic Information Processing "Folding, sorting and degradation" 111 3760 164 8888 0.676829268 3.27E-11 9.54E-09 4010 MAPK signaling pathway Environmental Information Processing Signal transduction 200 3760 335 8888 0.597014925 5.03E-11 1.47E-08 4140 Autophagy - animal Cellular Processes Transport and catabolism 101 3760 149 8888 0.677852349 2.22E-10 6.48E-08 4115 p53 signaling pathway Cellular Processes Cell growth and death 59 3760 79 8888 0.746835443 4.53E-09 1.32E-06 4012 ErbB signaling pathway Environmental Information Processing Signal transduction 68 3760 96 8888 0.708333333 1.25E-08 3.66E-06 4390 Hippo signaling pathway Environmental Information Processing Signal transduction 107 3760 169 8888 0.633136095 2.29E-08 6.70E-06 4810 Regulation of actin cytoskeleton Cellular Processes Cell motility 140 3760 235 8888 0.595744681 5.06E-08 1.48E-05 3030 DNA replication Genetic Information Processing Replication and repair 31 3760 36 8888 0.861111111 6.71E-08 1.96E-05 4068 FoxO signaling pathway Environmental Information Processing Signal transduction 92 3760 143 8888 0.643356643 7.29E-08 2.13E-05 4150 mTOR signaling pathway Environmental Information Processing Signal transduction 102 3760 162 8888 0.62962963 7.38E-08 2.15E-05 4910 Insulin signaling pathway Organismal Systems Endocrine system 94 3760 147 8888 0.639455782 8.14E-08 2.38E-05 4013 MAPK signaling pathway - fly Environmental Information Processing Signal transduction 63 3760 90 8888 0.7 8.81E-08 2.57E-05 4550 Signaling pathways regulating pluripotency of stem cells Cellular Processes Cellular community - eukaryotes 94 3760 148 8888 0.635135135 1.31E-07 3.83E-05 4919 Thyroid hormone signaling pathway Organismal Systems Endocrine system 82 3760 127 8888 0.645669291 2.96E-07 8.66E-05 4350 TGF-beta signaling pathway Environmental Information Processing Signal transduction 64 3760 94 8888 0.680851064 3.53E-07 1.03E-04 4310 Wnt signaling pathway Environmental Information Processing Signal transduction 97 3760 156 8888 0.621794872 3.65E-07 1.07E-04 1130 Biosynthesis of antibiotics Metabolism Global and overview maps 156 3760 273 8888 0.571428571 3.87E-07 1.13E-04 4211 Longevity regulating pathway Organismal Systems Aging 65 3760 96 8888 0.677083333 3.92E-07 1.15E-04 4152 AMPK signaling pathway Environmental Information Processing Signal transduction 86 3760 137 8888 0.627737226 9.32E-07 2.72E-04 3050 Proteasome Genetic Information Processing "Folding, sorting and degradation" 38 3760 50 8888 0.76 1.26E-06 3.68E-04 4914 Progesterone-mediated oocyte maturation Organismal Systems Endocrine system 65 3760 99 8888 0.656565657 2.10E-06 6.14E-04 4611 Platelet activation Organismal Systems Immune system 87 3760 142 8888 0.612676056 3.51E-06 0.001024599 4728 Dopaminergic synapse Organismal Systems Nervous system 87 3760 142 8888 0.612676056 3.51E-06 0.001024599 4214 Apoptosis - fly Cellular Processes Cell growth and death 43 3760 60 8888 0.716666667 3.72E-06 0.001086812 1110 Biosynthesis of secondary metabolites Metabolism Global and overview maps 246 3760 470 8888 0.523404255 4.30E-06 0.001256893 4137 Mitophagy - animal Cellular Processes Transport and catabolism 50 3760 73 8888 0.684931507 5.15E-06 0.001504659 4520 Adherens junction Cellular Processes Cellular community - eukaryotes 56 3760 84 8888 0.666666667 5.24E-06 0.001529511 4070 Phosphatidylinositol signaling system Environmental Information Processing Signal transduction 65 3760 101 8888 0.643564356 5.86E-06 0.001710648 4512 ECM-receptor interaction Environmental Information Processing Signaling molecules and interaction 59 3760 90 8888 0.655555556 6.65E-06 0.001940712 4926 Relaxin signaling pathway Organismal Systems Endocrine system 87 3760 144 8888 0.604166667 7.84E-06 0.00228868 4921 Oxytocin signaling pathway Organismal Systems Endocrine system 98 3760 166 8888 0.590361446 8.79E-06 0.002565252 3060 Protein export Genetic Information Processing "Folding, sorting and degradation" 24 3760 29 8888 0.827586207 9.26E-06 0.002702863 4341 Hedgehog signaling pathway - fly Environmental Information Processing Signal transduction 24 3760 29 8888 0.827586207 9.26E-06 0.002702863 4138 Autophagy - yeast Cellular Processes Transport and catabolism 51 3760 76 8888 0.671052632 1.03E-05 0.003020322 4015 Rap1 signaling pathway Environmental Information Processing Signal transduction 141 3760 254 8888 0.55511811 1.18E-05 0.003440563 4261 Adrenergic signaling in cardiomyocytes Organismal Systems Circulatory system 90 3760 151 8888 0.59602649 1.19E-05 0.003481913 4713 Circadian entrainment Organismal Systems Environmental adaptation 64 3760 101 8888 0.633663366 1.46E-05 0.00425409 513 Various types of N-glycan biosynthesis Metabolism Glycan biosynthesis and metabolism 31 3760 41 8888 0.756097561 1.48E-05 0.004311894 4111 Cell cycle - yeast Cellular Processes Cell growth and death 49 3760 73 8888 0.671232877 1.52E-05 0.004442879 4212 Longevity regulating pathway - worm Organismal Systems Aging 56 3760 86 8888 0.651162791 1.53E-05 0.004479368 4071 Sphingolipid signaling pathway Environmental Information Processing Signal transduction 83 3760 138 8888 0.601449275 1.60E-05 0.004681443 3420 Nucleotide excision repair Genetic Information Processing Replication and repair 35 3760 48 8888 0.729166667 1.62E-05 0.004744232 4213 Longevity regulating pathway - multiple species Organismal Systems Aging 52 3760 79 8888 0.658227848 1.96E-05 0.005715006 4714 Thermogenesis Organismal Systems Environmental adaptation 138 3760 250 8888 0.552 2.13E-05 0.006230413 4722 Neurotrophin signaling pathway Organismal Systems Nervous system 80 3760 133 8888 0.601503759 2.26E-05 0.006596978 240 Pyrimidine metabolism Metabolism Nucleotide metabolism 66 3760 106 8888 0.622641509 2.48E-05 0.007236867 4668 TNF signaling pathway Environmental Information Processing Signal transduction 72 3760 118 8888 0.610169492 2.92E-05 0.008515751 4066 HIF-1 signaling pathway Environmental Information Processing Signal transduction 78 3760 130 8888 0.6 3.23E-05 0.009423515 4011 MAPK signaling pathway - yeast Environmental Information Processing Signal transduction 35 3760 49 8888 0.714285714 3.38E-05 0.009862058 4210 Apoptosis Cellular Processes Cell growth and death 93 3760 160 8888 0.58125 3.48E-05 0.01016765 520 Amino sugar and nucleotide sugar metabolism Metabolism Carbohydrate metabolism 36 3760 51 8888 0.705882353 3.95E-05 0.01154062 4113 Meiosis - yeast Cellular Processes Cell growth and death 42 3760 62 8888 0.677419355 4.41E-05 0.01286391 4380 Osteoclast differentiation Organismal Systems Development 84 3760 143 8888 0.587412587 4.87E-05 0.01422101 4340 Hedgehog signaling pathway Environmental Information Processing Signal transduction 33 3760 46 8888 0.717391304 4.92E-05 0.0143629 4371 Apelin signaling pathway Environmental Information Processing Signal transduction 87 3760 151 8888 0.57615894 9.54E-05 0.02786201 4142 Lysosome Cellular Processes Transport and catabolism 85 3760 147 8888 0.578231293 9.61E-05 0.02807483 4139 Mitophagy - yeast Cellular Processes Transport and catabolism 22 3760 28 8888 0.785714286 1.00E-04 0.02928345 4912 GnRH signaling pathway Organismal Systems Endocrine system 61 3760 100 8888 0.61 1.18E-04 0.03434577 230 Purine metabolism Metabolism Nucleotide metabolism 107 3760 193 8888 0.554404145 1.39E-04 0.0405294